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CAKLQF020000003.1__CAH1076665.1__SAMEA5780031_00894__00221

Bact-Vir

CAKLQF020000003.1__CAH1076665.1__SAMEA5780031_00894__00221

Identity

Kingdom:
phage

Quality

92.4 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1-67
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF16078.11 best 2-oxogl_dehyd_N 57.3 1.30e-15 61.2% 90.2%
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2xz2A00 1.20.960.50 Mainly Alpha › Up-down Bundle › Mitochondrial Import Receptor Subunit Tom20; Chain A › Cleavage stimulation factor subunit 1, dimerisation domain 0.53 37.0 3.75e-01 74.6% 81.8%
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3946273 7574.1.1.0 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) 0.71 58.0 3.40e-01 86.6% 11.3%
D2 high residues 84-163
PDB
Domain cluster: representative
CATH (9)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2jgdA01 1.10.287.1150 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › TPP helical domain 0.98 86.0 8.89e-01 100.0% 96.1%
5ygqA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.59 44.0 3.21e-01 88.7% 28.8%
1hyuA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.58 41.0 3.19e-01 90.0% 32.4%
2rd9B01 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.55 41.0 3.18e-01 78.8% 72.6%
3p4tA01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.53 46.0 4.09e-01 100.0% 66.4%
4mloA03 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.53 37.0 3.97e-01 100.0% 96.7%
2obpA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 40.0 4.02e-01 97.5% 84.0%
2f22A00 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.51 38.0 3.18e-01 100.0% 45.1%
3ipiA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.50 44.0 3.09e-01 100.0% 30.6%
ECOD (9)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3946273 7574.1.1.0 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) 0.99 96.0 5.58e-01 100.0% 15.1%
3258899 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.92 57.0 3.48e-01 92.5% 12.1%
4442719 7574.1.1.14 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh+Transket_pyr 0.92 87.0 4.89e-01 100.0% 11.0%
4532425 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.91 86.0 5.08e-01 100.0% 16.0%
3698185 3817.1.1.1 alpha bundles › Peroxisomal biogenesis factor 19 › Peroxisomal biogenesis factor 19 › Peroxisomal biogenesis factor 19 › Pex19 0.57 39.0 3.49e-01 87.5% 49.6%
3572552 109.4.1.908 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_DOP1 0.51 42.0 2.99e-01 93.8% 29.6%
4028 620.1.1.2 alpha bundles › YfiT-like putative metal-dependent hydrolases › YfiT-like putative metal-dependent hydrolases › YfiT-like putative metal-dependent hydrolases › DinB 0.51 38.0 3.19e-01 100.0% 45.4%
3691994 109.4.1.356 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.51 43.0 2.97e-01 100.0% 25.1%
5061554 304.111.1.1 a+b two layers › Alpha-beta plaits › PurM C-terminal domain-like › PurM C-terminal domain-like › AIRS_C 0.50 38.0 3.04e-01 86.3% 64.7%
D3 high residues 805-935
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF16870.11 best OxoGdeHyase_C 161.1 2.30e-47 100.0% 87.4%
CATH (96)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2jgdA04 3.40.50.11610 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain 0.96 91.0 8.39e-01 100.0% 80.5%
7wgrA03 3.40.50.11610 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain 0.93 89.0 8.95e-01 100.0% 99.2%
1umdB02 3.40.50.920 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.79 69.0 7.05e-01 100.0% 95.3%
4kxwA03 3.40.50.920 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.79 69.0 6.91e-01 100.0% 91.0%
2bfdB02 3.40.50.920 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.79 69.0 7.11e-01 100.0% 98.4%
2ozlB02 3.40.50.920 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.79 70.0 7.00e-01 100.0% 93.3%
2c42A02 3.40.50.920 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.79 68.0 6.33e-01 100.0% 75.8%
6n2nC03 3.40.50.920 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.77 61.0 6.56e-01 100.0% 97.3%
5exeA02 3.40.50.920 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.77 66.0 6.40e-01 100.0% 82.6%
1gpuA03 3.40.50.920 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.75 62.0 6.15e-01 100.0% 83.9%
2pjuC01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.74 50.0 5.58e-01 92.4% 89.0%
4tkzA00 3.40.50.510 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphotransferase system, mannose-type IIA component 0.73 53.0 5.34e-01 92.4% 74.6%
3l84A03 3.40.50.920 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.73 60.0 6.31e-01 100.0% 96.6%
3iprA00 3.40.50.510 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphotransferase system, mannose-type IIA component 0.71 54.0 5.32e-01 92.4% 75.2%
1pdoA00 3.40.50.510 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphotransferase system, mannose-type IIA component 0.71 51.0 5.19e-01 92.4% 76.0%
1ae1A00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.70 60.0 4.85e-01 93.1% 87.3%
2oqrA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.69 42.0 5.19e-01 71.8% 100.0%
1bgwA02 3.40.50.670 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.68 62.0 5.69e-01 100.0% 88.9%
1d3yB02 3.40.1360.10 Alpha Beta › 3-Layer(aba) Sandwich › Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 › 0.68 62.0 5.24e-01 100.0% 95.9%
4h08A00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.68 63.0 5.41e-01 100.0% 92.0%
6s8oB02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.68 50.0 4.30e-01 77.9% 59.4%
3p94A00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.68 61.0 5.29e-01 100.0% 91.2%
4iuyA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.67 57.0 4.62e-01 92.4% 87.7%
2hsjD00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.67 61.0 5.18e-01 100.0% 90.2%
4impA02 3.40.50.11460 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.67 57.0 4.89e-01 92.4% 77.3%
5im4F00 3.40.50.510 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphotransferase system, mannose-type IIA component 0.67 50.0 5.03e-01 92.4% 77.9%
1oi2A01 3.40.50.10440 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Dihydroxyacetone kinase; domain 1 0.66 58.0 5.33e-01 100.0% 72.8%
7ntgA01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.66 56.0 5.07e-01 91.6% 74.0%
1zzgA02 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.66 56.0 5.17e-01 92.4% 79.3%
1di0A00 3.40.50.960 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Lumazine/riboflavin synthase 0.66 57.0 5.50e-01 94.7% 87.8%
6q2eA01 3.40.50.11840 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Diphthamide synthesis DPH1/DPH2 domain 1 0.65 38.0 4.51e-01 70.2% 85.1%
2vptA00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.65 55.0 4.81e-01 92.4% 93.5%
8alzB05 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.65 48.0 4.17e-01 77.1% 62.4%
3nutC01 3.40.1010.10 Alpha Beta › 3-Layer(aba) Sandwich › Cobalt-precorrin-4 Transmethylase; domain 1 › Tetrapyrrole methylase, N-terminal domain 0.65 42.0 4.51e-01 73.3% 75.4%
3h7aA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.64 55.0 4.74e-01 94.7% 91.0%
2b99C00 3.40.50.960 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Lumazine/riboflavin synthase 0.64 54.0 5.21e-01 93.1% 80.3%
6iubA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.64 55.0 4.36e-01 93.1% 98.5%
5owvD01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.64 55.0 4.59e-01 93.1% 91.0%
2jh3A02 3.40.50.1400 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.63 47.0 4.90e-01 87.8% 83.7%
4c6sA00 3.40.50.10140 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Toll/interleukin-1 receptor homology (TIR) domain 0.63 54.0 5.30e-01 93.1% 93.0%
1eucB03 3.40.50.261 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Succinyl-CoA synthetase domains 0.63 57.0 5.49e-01 100.0% 87.7%
3s99A01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.63 51.0 5.06e-01 92.4% 82.4%
3l41A02 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.63 42.0 4.45e-01 92.4% 77.9%
2p6rA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.63 50.0 4.37e-01 84.7% 70.1%
2vhaA02 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.62 38.0 4.28e-01 88.5% 81.2%
2ex2A02 3.50.80.20 Alpha Beta › 3-Layer(bba) Sandwich › D-tyrosyl-trna(Tyr) Deacylase; Chain: A; › D-Ala-D-Ala carboxypeptidase C, peptidase S13 0.62 43.0 4.73e-01 100.0% 89.3%
1m32A02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.62 52.0 4.18e-01 90.1% 58.5%
5di3B00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.62 53.0 4.56e-01 93.1% 78.4%
3g0tA03 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.61 52.0 4.48e-01 92.4% 81.6%
3brsA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.61 51.0 5.09e-01 92.4% 86.1%
1zghA01 3.40.50.170 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Formyl transferase, N-terminal domain 0.61 52.0 4.83e-01 92.4% 87.3%
4c6rA00 3.40.50.10140 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Toll/interleukin-1 receptor homology (TIR) domain 0.61 52.0 4.87e-01 93.9% 95.1%
1dcfA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.60 50.0 4.98e-01 92.4% 87.2%
3a0uA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.60 48.0 5.09e-01 94.7% 96.5%
7e7gA01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.60 50.0 4.05e-01 90.1% 56.9%
3breB01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.60 50.0 4.89e-01 93.9% 81.8%
1t3gB00 3.40.50.10140 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Toll/interleukin-1 receptor homology (TIR) domain 0.60 51.0 4.91e-01 93.1% 98.7%
2dr1A02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.60 50.0 4.08e-01 90.8% 58.9%
3oy2A01 3.40.50.11930 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.59 51.0 4.74e-01 91.6% 100.0%
4o5aA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.59 47.0 4.74e-01 93.9% 84.8%
3f0hA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.59 49.0 3.93e-01 90.1% 53.8%
1eluA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.59 50.0 3.99e-01 91.6% 54.2%
3om0A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.59 50.0 4.69e-01 90.1% 86.9%
3ilhA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.59 51.0 5.09e-01 93.1% 94.0%
2ftyA02 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.59 49.0 3.51e-01 90.8% 80.8%
3eodA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.59 46.0 4.86e-01 92.4% 93.9%
2mr5A00 3.40.50.11230 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.58 49.0 4.92e-01 91.6% 88.2%
2yc4C00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 50.0 4.55e-01 93.1% 82.5%
2ymbA00 3.30.870.30 Alpha Beta › 2-Layer Sandwich › Endonuclease; Chain A › MITD, C-terminal phospholipase D-like domain 0.58 41.0 3.93e-01 100.0% 62.1%
2csuA02 3.40.50.261 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Succinyl-CoA synthetase domains 0.58 53.0 5.21e-01 100.0% 93.6%
4rk0A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.58 45.0 4.50e-01 88.5% 80.6%
2z9vA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.58 48.0 3.93e-01 90.1% 59.8%
4joqA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.58 49.0 4.82e-01 94.7% 86.5%
2pv7A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.57 50.0 4.66e-01 93.1% 84.9%
3iwtA00 3.40.980.10 Alpha Beta › 3-Layer(aba) Sandwich › Molybdenum Cofactor Biosythetic Enzyme; Chain A › MoaB/Mog-like domain 0.57 48.0 4.44e-01 92.4% 91.0%
8gj8A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 47.0 3.85e-01 90.8% 73.2%
1wy5A01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.56 45.0 3.83e-01 100.0% 51.6%
3ju3A00 3.40.50.920 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.56 44.0 4.63e-01 100.0% 93.1%
2l82A00 3.40.50.11230 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.56 47.0 4.45e-01 92.4% 90.1%
1np3B01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 47.0 4.27e-01 92.4% 85.2%
2f6uA00 3.20.20.390 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › FMN-linked oxidoreductases 0.56 48.0 3.97e-01 93.1% 58.9%
2ynmD03 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.55 47.0 4.26e-01 92.4% 70.1%
4lw2A02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.55 45.0 3.66e-01 89.3% 49.0%
3cr8C02 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.55 46.0 4.12e-01 95.4% 94.9%
3ly1A02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.55 45.0 3.88e-01 92.4% 64.9%
1gu7A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 46.0 4.13e-01 91.6% 83.4%
5ahkA01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.54 45.0 4.08e-01 91.6% 88.5%
2bgwB01 3.40.50.10130 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.53 44.0 4.48e-01 98.5% 90.1%
4am8E01 3.40.50.1370 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase 0.53 44.0 4.10e-01 92.4% 71.3%
3uwpA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.53 44.0 3.77e-01 91.6% 72.7%
5cxpA02 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.53 48.0 3.75e-01 100.0% 75.6%
1knwA02 3.20.20.10 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase 0.52 45.0 3.70e-01 95.4% 71.0%
2pgnA01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.52 43.0 3.92e-01 92.4% 82.9%
1losA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.52 40.0 3.42e-01 82.4% 81.9%
4dzrA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 45.0 4.26e-01 98.5% 96.9%
4m1bA00 3.20.20.370 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycoside hydrolase/deacetylase 0.51 41.0 3.61e-01 87.8% 88.5%
ECOD (99)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3182560 7522.1.1.3 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › OxoGdeHyase_C 0.98 95.0 8.91e-01 100.0% 90.2%
4029893 7522.1.1.3 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › OxoGdeHyase_C 0.97 95.0 8.70e-01 100.0% 88.7%
4318842 7522.1.1.3 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › OxoGdeHyase_C 0.97 93.0 9.07e-01 100.0% 92.1%
4302576 7522.1.1.3 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › OxoGdeHyase_C 0.97 91.0 9.09e-01 100.0% 94.8%
1308391 7522.1.1.3 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › OxoGdeHyase_C 0.96 91.0 8.12e-01 100.0% 74.4%
3595935 7522.1.1.0 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like 0.95 88.0 8.90e-01 99.2% 96.2%
3771364 7522.1.1.3 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › OxoGdeHyase_C 0.95 90.0 8.91e-01 100.0% 94.1%
3940898 7522.1.1.3 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › OxoGdeHyase_C 0.95 90.0 8.61e-01 100.0% 88.2%
3600351 7522.1.1.0 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like 0.94 92.0 8.79e-01 100.0% 96.6%
3320245 7522.1.1.3 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › OxoGdeHyase_C 0.94 92.0 8.53e-01 100.0% 86.5%
3567975 7522.1.1.3 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › OxoGdeHyase_C 0.94 91.0 8.85e-01 100.0% 92.9%
3611621 7522.1.1.3 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › OxoGdeHyase_C 0.94 91.0 8.63e-01 100.0% 95.9%
1306682 7522.1.1.3 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › OxoGdeHyase_C 0.94 91.0 8.54e-01 100.0% 87.5%
4082717 7522.1.1.3 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › OxoGdeHyase_C 0.93 90.0 8.49e-01 100.0% 88.7%
3607589 7522.1.1.3 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › OxoGdeHyase_C 0.92 86.0 8.72e-01 100.0% 97.7%
3723137 7522.1.1.3 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › OxoGdeHyase_C 0.86 74.0 7.03e-01 93.1% 77.3%
3340289 7522.1.1.1 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › Transketolase_C 0.82 72.0 6.95e-01 100.0% 83.4%
4937007 7522.1.1.1 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › Transketolase_C 0.81 70.0 7.11e-01 100.0% 92.3%
4385053 7522.1.1.6 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › PF30897 0.81 65.0 5.94e-01 100.0% 66.1%
5037551 7522.1.1.0 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like 0.81 65.0 6.44e-01 100.0% 81.5%
4995481 7522.1.1.6 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › PF30897 0.79 64.0 6.09e-01 100.0% 73.3%
5014869 7522.1.1.0 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like 0.79 62.0 6.61e-01 96.9% 93.0%
5017188 7522.1.1.6 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › PF30897 0.79 63.0 5.75e-01 100.0% 66.1%
4980832 7522.1.1.0 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like 0.79 67.0 6.32e-01 100.0% 76.1%
3676650 7522.1.1.1 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › Transketolase_C 0.78 69.0 6.72e-01 100.0% 85.5%
3170897 7522.1.1.0 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like 0.78 67.0 6.68e-01 100.0% 88.1%
3599418 7522.1.1.0 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like 0.78 69.0 6.89e-01 100.0% 92.6%
4352329 7522.1.1.1 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › Transketolase_C 0.77 70.0 6.83e-01 100.0% 90.0%
3741295 7522.1.1.0 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like 0.77 63.0 6.38e-01 100.0% 86.9%
4038962 7522.1.1.1 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › Transketolase_C 0.77 68.0 6.59e-01 100.0% 85.5%
4497015 7522.1.1.1 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › Transketolase_C 0.77 68.0 6.68e-01 100.0% 88.6%
1564347 7522.1.1.4 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › PFOR_II 0.77 66.0 6.37e-01 100.0% 82.1%
4488757 7522.1.1.1 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › Transketolase_C 0.77 68.0 6.69e-01 100.0% 89.3%
4493970 7522.1.1.1 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › Transketolase_C 0.77 70.0 6.82e-01 100.0% 89.7%
5064772 7522.1.1.4 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › PFOR_II 0.76 67.0 5.81e-01 100.0% 63.7%
4946545 7522.1.1.0 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like 0.76 59.0 6.31e-01 100.0% 93.0%
3953569 7522.1.1.1 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › Transketolase_C 0.76 69.0 6.79e-01 100.0% 92.1%
4400778 7522.1.1.1 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › Transketolase_C 0.75 70.0 6.87e-01 100.0% 94.9%
5060027 7522.1.1.6 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › PF30897 0.75 61.0 6.12e-01 100.0% 84.4%
5056335 7522.1.1.1 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › Transketolase_C 0.75 66.0 6.60e-01 100.0% 92.6%
3978164 2010.1.1.3 a/b three-layered sandwiches › EDD domain › EDD domain › EDD domain › EIIA-man 0.74 53.0 5.26e-01 93.1% 71.1%
5021609 7522.1.1.4 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › PFOR_II 0.73 58.0 6.22e-01 100.0% 96.5%
3989133 2010.1.1.3 a/b three-layered sandwiches › EDD domain › EDD domain › EDD domain › EIIA-man 0.72 54.0 5.20e-01 93.1% 69.7%
5019274 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.72 52.0 4.81e-01 75.6% 75.9%
4448610 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.70 48.0 4.24e-01 90.1% 47.2%
4588442 7591.1.1.1 a/b three-layered sandwiches › Tetraacyldisaccharide 4'-kinase C-terminal domain › Tetraacyldisaccharide 4'-kinase C-terminal domain › Tetraacyldisaccharide 4'-kinase C-terminal domain › LpxK 0.68 48.0 4.89e-01 83.2% 74.4%
5079125 2004.1.1.29 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.68 49.0 4.08e-01 74.8% 55.2%
5072840 2006.1.3.11 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › TOP6A-Spo11_Toprim 0.68 61.0 5.11e-01 99.2% 98.2%
3838443 2006.1.3.6 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim_2 0.67 57.0 5.90e-01 98.5% 96.0%
5047978 7576.1.1.0 a/b three-layered sandwiches › Gingipain R extra N-terminal alpha/beta domain › Gingipain R extra N-terminal alpha/beta domain › Gingipain R extra N-terminal alpha/beta domain 0.67 55.0 5.70e-01 92.4% 93.3%
3828982 7510.1.1.0 a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like 0.67 52.0 4.96e-01 94.7% 69.5%
4972048 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.67 55.0 3.74e-01 87.0% 60.2%
3383505 2006.1.3.11 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › TOP6A-Spo11_Toprim 0.67 58.0 5.29e-01 94.7% 98.3%
4975785 2007.1.13.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Lumazine synthase › DMRL_synthase 0.66 56.0 5.35e-01 93.1% 78.7%
4952313 2007.22.1.1 a/b three-layered sandwiches › Flavodoxin-like › Methyl-viologen reducing hydrogenase subunit D › Methyl-viologen reducing hydrogenase subunit D › FlpD 0.66 52.0 5.37e-01 93.1% 91.7%
4956039 2007.1.13.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Lumazine synthase › DMRL_synthase 0.65 55.0 5.44e-01 92.4% 89.3%
5059861 2007.6.1.5 a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › bact-PGI_C 0.65 53.0 4.95e-01 92.4% 69.0%
5038863 2007.1.13.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Lumazine synthase › DMRL_synthase 0.65 55.0 5.16e-01 93.1% 77.0%
3185671 7568.1.1.0 a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain 0.65 46.0 4.92e-01 92.4% 83.5%
3841808 2007.1.6.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Aminoacid dehydrogenase-like, N-terminal domain 0.64 43.0 4.63e-01 71.0% 80.9%
3823490 2007.1.2.4 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ANF_receptor 0.64 53.0 4.67e-01 87.8% 66.5%
3609036 2004.1.1.211 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › CLP1_P 0.64 51.0 4.11e-01 84.7% 80.0%
3595184 7577.1.1.0 a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases 0.63 53.0 4.22e-01 90.8% 55.1%
3596496 2007.25.1.0 a/b three-layered sandwiches › Flavodoxin-like › Rossmann-like domain in Ribosomal protein L1 › Rossmann-like domain in Ribosomal protein L1 0.63 53.0 5.46e-01 93.1% 94.4%
3958965 323.1.1.0 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.63 44.0 4.26e-01 72.5% 90.0%
3246245 2005.1.1.36 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › SLC12 0.63 51.0 4.62e-01 87.0% 99.4%
4937009 2007.6.1.0 a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain 0.63 54.0 5.21e-01 92.4% 85.5%
3366498 2007.1.3.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like 0.62 55.0 5.21e-01 96.2% 85.8%
4996168 2007.1.13.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Lumazine synthase 0.62 53.0 5.12e-01 100.0% 84.1%
4385737 2007.1.9.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) › AIRC 0.62 53.0 5.17e-01 98.5% 83.4%
3967791 2007.3.1.3 a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains › Succ_CoA_lig 0.62 56.0 5.15e-01 100.0% 91.2%
4951984 2007.3.1.3 a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains › Succ_CoA_lig 0.61 56.0 5.13e-01 100.0% 88.8%
4983543 2007.3.1.3 a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains › Succ_CoA_lig 0.61 56.0 4.98e-01 100.0% 89.2%
4275162 2005.1.1.11 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › ATP_bind_3 0.61 45.0 3.72e-01 77.1% 86.5%
4938803 2007.3.1.3 a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains › Succ_CoA_lig 0.61 55.0 5.02e-01 100.0% 88.6%
5044161 2007.3.1.3 a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains › Succ_CoA_lig 0.61 55.0 5.03e-01 100.0% 88.6%
5065635 2007.3.1.3 a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains › Succ_CoA_lig 0.61 56.0 5.04e-01 100.0% 86.3%
4946606 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.61 52.0 4.76e-01 93.1% 84.5%
3395584 2005.1.1.36 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › SLC12 0.61 49.0 4.62e-01 86.3% 100.0%
4989268 2007.22.1.1 a/b three-layered sandwiches › Flavodoxin-like › Methyl-viologen reducing hydrogenase subunit D › Methyl-viologen reducing hydrogenase subunit D › FlpD 0.61 50.0 4.81e-01 100.0% 78.7%
3652604 2007.9.1.0 a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain 0.60 52.0 4.64e-01 94.7% 83.7%
4980310 2007.3.1.0 a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains 0.60 55.0 5.07e-01 100.0% 94.5%
4944763 2007.3.1.3 a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains › Succ_CoA_lig 0.60 54.0 5.07e-01 100.0% 95.0%
4957000 2007.3.1.3 a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains › Succ_CoA_lig 0.60 54.0 5.29e-01 100.0% 91.7%
4991138 7577.1.1.3 a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_5 0.59 49.0 3.88e-01 90.1% 48.9%
5006460 2007.3.1.3 a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains › Succ_CoA_lig 0.59 54.0 4.98e-01 100.0% 92.7%
5075408 2007.3.1.3 a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains › Succ_CoA_lig 0.59 53.0 4.99e-01 99.2% 92.5%
5010556 7577.1.1.3 a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_5 0.59 49.0 3.81e-01 90.1% 50.0%
5076202 7577.1.1.3 a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_5 0.59 48.0 3.70e-01 90.1% 46.7%
3289646 2007.9.1.4 a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR_2 0.59 50.0 4.97e-01 94.7% 90.7%
4948004 7577.1.1.3 a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_5 0.59 48.0 3.96e-01 90.1% 58.4%
3777637 2007.9.1.1 a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR 0.58 50.0 4.42e-01 93.9% 83.7%
3926234 323.1.1.0 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.58 50.0 4.20e-01 94.7% 85.3%
4970052 2007.3.1.3 a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains › Succ_CoA_lig 0.57 51.0 4.69e-01 99.2% 82.3%
2754667 2007.3.1.3 a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains › Succ_CoA_lig 0.57 51.0 4.81e-01 100.0% 93.9%
4965658 2004.1.1.1217 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF7125 0.57 47.0 4.11e-01 90.8% 75.1%
3549056 2005.1.1.36 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › SLC12 0.56 46.0 4.12e-01 86.3% 77.2%
3664605 207.1.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.56 44.0 4.05e-01 100.0% 62.9%
3272173 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.55 46.0 4.60e-01 92.4% 87.4%
D4 medium residues 179-189_372-480
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00676.26 best E1_dh 105.1 5.00e-30 94.2% 35.3%
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6sy1A02 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.97 94.0 6.32e-01 100.0% 83.7%
1qs0A00 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.77 72.0 4.86e-01 100.0% 73.2%
2nxwA01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.76 47.0 4.05e-01 70.8% 41.1%
2jgdB02 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.74 73.0 5.01e-01 100.0% 80.2%
2ihuA01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.69 46.0 3.97e-01 71.7% 43.8%
3qdnA01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.62 36.0 3.71e-01 70.8% 59.3%
5kwaA03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.59 46.0 4.09e-01 82.5% 88.8%
7r5yA01 3.40.50.1240 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphoglycerate mutase-like 0.59 40.0 2.84e-01 70.8% 77.5%
1r85A00 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.56 39.0 2.84e-01 72.5% 88.9%
3gfoA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 40.0 3.14e-01 74.2% 84.9%
5e7pA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 41.0 3.68e-01 80.0% 89.6%
2zshA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.54 47.0 3.51e-01 100.0% 54.4%
2vdwG00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.53 36.0 2.87e-01 70.0% 65.6%
1yawB01 3.30.1330.10 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › PurM-like, N-terminal domain 0.53 28.0 2.79e-01 75.0% 44.8%
1nlfA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 40.0 3.17e-01 79.2% 76.4%
3lkbA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 37.0 3.31e-01 71.7% 94.6%
3qh4A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.52 46.0 3.45e-01 100.0% 52.2%
1g6hA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 41.0 3.23e-01 85.0% 99.2%
5hn3A00 3.40.718.10 Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase 0.52 36.0 2.69e-01 72.5% 87.7%
3upuA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 36.0 3.25e-01 74.2% 88.1%
4evsA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.50 36.0 3.22e-01 73.3% 96.5%
ECOD (54)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3946273 7574.1.1.0 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) 1.00 98.0 6.05e-01 100.0% 57.0%
4652217 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.99 98.0 6.25e-01 100.0% 67.6%
4532425 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.98 96.0 6.01e-01 100.0% 62.6%
4442719 7574.1.1.14 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh+Transket_pyr 0.98 96.0 5.63e-01 100.0% 42.2%
4027848 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.98 96.0 6.06e-01 100.0% 64.4%
3723138 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.98 96.0 6.07e-01 100.0% 64.7%
4199309 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.98 96.0 6.07e-01 100.0% 68.6%
4852210 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.97 95.0 6.11e-01 100.0% 69.0%
3258899 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.97 95.0 6.17e-01 100.0% 72.6%
3933130 7574.1.1.14 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh+Transket_pyr 0.97 95.0 5.53e-01 100.0% 40.9%
4554292 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.97 95.0 5.98e-01 100.0% 66.0%
3897384 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.97 95.0 6.05e-01 100.0% 68.8%
3595923 7574.1.1.0 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) 0.97 94.0 6.00e-01 100.0% 66.7%
3611613 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.96 94.0 5.92e-01 100.0% 62.3%
3703007 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.96 93.0 5.90e-01 100.0% 64.8%
3717974 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.89 73.0 6.19e-01 90.8% 56.7%
3817925 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.88 74.0 5.77e-01 90.8% 45.1%
None 0.87 73.0 5.18e-01 90.8% 32.8%
4034009 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.87 73.0 5.17e-01 90.8% 32.8%
3594591 7574.1.1.0 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) 0.85 77.0 5.02e-01 95.0% 62.9%
5052546 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.85 72.0 5.08e-01 90.8% 32.3%
None 0.85 71.0 4.96e-01 90.8% 30.0%
None 0.85 71.0 4.94e-01 90.8% 29.7%
3708583 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.85 75.0 4.99e-01 92.5% 66.6%
None 0.84 75.0 5.02e-01 93.3% 67.8%
3215665 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.83 73.0 4.87e-01 92.5% 64.1%
10703 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.82 75.0 5.15e-01 95.8% 80.1%
4073613 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.82 72.0 5.02e-01 92.5% 72.4%
3286832 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.81 73.0 5.09e-01 95.0% 74.6%
3328499 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.79 75.0 5.09e-01 100.0% 76.1%
10705 7574.1.1.3 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh,OxoDH_E1alpha_N 0.77 72.0 4.86e-01 100.0% 73.2%
1170918 7574.1.1.7 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_N 0.76 47.0 4.16e-01 70.8% 44.3%
3960028 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.75 59.0 5.71e-01 90.8% 73.3%
3970093 7574.1.1.0 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) 0.72 47.0 4.04e-01 72.5% 42.7%
5023835 7574.1.1.0 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) 0.71 47.0 4.18e-01 90.8% 47.6%
3290887 7574.1.1.5 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_C 0.71 53.0 4.18e-01 76.7% 47.0%
5005751 7574.1.1.7 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_N 0.71 47.0 4.03e-01 71.7% 44.4%
4054013 7574.1.1.7 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_N 0.70 49.0 4.23e-01 75.8% 46.5%
4360859 7574.1.1.7 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_N 0.70 48.0 4.74e-01 70.8% 65.4%
5018381 7574.1.1.7 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_N 0.69 46.0 3.88e-01 71.7% 42.1%
3665198 2485.1.1.1 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › Thioredoxin 0.67 38.0 3.75e-01 70.8% 51.5%
2703489 7523.1.1.23 a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › PBP_like_2 0.62 26.0 3.04e-01 79.2% 51.7%
2475239 2485.1.1.42 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › Thioredoxin_5 0.62 27.0 3.82e-01 85.8% 95.9%
3498980 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.61 39.0 3.85e-01 70.8% 58.5%
3602784 2007.1.16.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Iron-sulphur enzyme Dph2 › Diphthamide_syn 0.58 29.0 3.08e-01 75.8% 53.3%
4979458 2004.1.1.98 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Rad17 0.57 42.0 3.84e-01 76.7% 73.8%
3252498 2004.1.1.194 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C_2 0.56 42.0 3.40e-01 77.5% 48.0%
5052848 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.56 41.0 3.52e-01 75.8% 48.4%
3580753 2004.1.1.194 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C_2 0.56 42.0 3.21e-01 80.0% 38.0%
3742314 2004.1.1.499 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD_2, Helicase_C_2 0.55 42.0 2.70e-01 80.0% 18.4%
3735660 2004.1.1.499 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD_2, Helicase_C_2 0.54 41.0 2.59e-01 80.0% 16.6%
4545908 2004.1.1.429 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_15 0.53 41.0 2.94e-01 82.5% 98.9%
4024569 2006.1.1.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like 0.52 35.0 2.96e-01 70.0% 77.2%
3940856 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.50 39.0 3.67e-01 81.7% 82.8%
D5 medium residues 190-224_481-520
PDB
Domain cluster: representative
CATH (31)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2jgdB02 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.95 92.0 5.74e-01 100.0% 89.3%
1ni4A00 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.84 74.0 4.65e-01 96.0% 82.9%
2odmA00 1.10.287.750 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like 0.72 55.0 5.46e-01 81.3% 89.9%
1hs7A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 49.0 4.57e-01 80.0% 83.5%
3rq9A00 1.10.287.2500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.66 53.0 5.24e-01 86.7% 100.0%
2uubT00 1.20.58.110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 0.66 51.0 4.65e-01 81.3% 67.7%
2dofA00 1.10.10.440 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › FF domain 0.66 54.0 5.22e-01 90.7% 78.8%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.65 49.0 4.32e-01 80.0% 89.9%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 44.0 4.03e-01 70.7% 93.1%
1q6aA00 1.10.1240.30 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › KaiA/RbsU domain 0.64 52.0 4.71e-01 90.7% 64.5%
5d0yA00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.64 51.0 4.04e-01 86.7% 41.9%
1owaA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 47.0 4.23e-01 80.0% 85.8%
2hxoA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.62 53.0 4.33e-01 96.0% 83.3%
1vkeB00 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.62 48.0 4.36e-01 88.0% 62.4%
1f2eA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.61 45.0 4.00e-01 77.3% 69.8%
4zqeA03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.61 51.0 4.64e-01 89.3% 85.4%
2gtvX00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.61 49.0 4.42e-01 89.3% 67.3%
2w9zA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.60 51.0 4.30e-01 97.3% 94.7%
1u61A00 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.59 43.0 3.55e-01 74.7% 78.0%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.59 47.0 4.06e-01 86.7% 92.3%
2kjfA00 1.20.225.10 Mainly Alpha › Up-down Bundle › Bacteriocin As-48; Chain A › Bacteriocin AS-48 0.59 39.0 4.18e-01 90.7% 83.3%
3a06B03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.58 48.0 4.59e-01 89.3% 83.0%
3lgdA00 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.58 50.0 3.04e-01 96.0% 30.1%
3pubA01 1.10.10.2400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Lepidopteran low molecular weight (30 kD) lipoprotein, N-terminal domain 0.57 39.0 4.00e-01 81.3% 73.0%
2ptfB02 1.20.58.290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121. 0.57 41.0 4.49e-01 82.7% 100.0%
2w02B01 1.10.150.640 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › AcsD, thumb domain, helical bundle 0.56 39.0 3.95e-01 86.7% 74.3%
2nn4A00 1.10.287.760 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YqgQ-like 0.56 37.0 4.01e-01 84.0% 82.3%
3hl1A02 6.10.140.1530 Special › Helix non-globular › Helix Hairpins › 0.56 39.0 4.14e-01 74.7% 87.7%
3ilkA02 1.10.8.590 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.52 35.0 3.70e-01 72.0% 76.5%
2qvwA04 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.52 41.0 3.25e-01 84.0% 73.8%
2vkzA02 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.51 38.0 2.64e-01 78.7% 30.9%
ECOD (34)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3306390 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.72 56.0 4.93e-01 81.3% 71.4%
4201754 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.71 52.0 4.78e-01 77.3% 66.3%
4095914 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.68 50.0 4.93e-01 77.3% 78.8%
4193935 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.68 53.0 5.08e-01 81.3% 77.6%
4474310 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.67 52.0 5.15e-01 81.3% 82.5%
3957298 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.67 52.0 4.89e-01 81.3% 73.3%
4270503 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.67 52.0 4.98e-01 81.3% 77.6%
4061821 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.67 51.0 4.97e-01 81.3% 73.8%
4563321 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.67 50.0 4.85e-01 81.3% 70.2%
4063100 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.66 51.0 5.03e-01 81.3% 82.5%
4181805 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.66 51.0 5.07e-01 81.3% 80.8%
4297853 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.66 48.0 3.96e-01 77.3% 79.3%
4231435 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.65 50.0 4.82e-01 81.3% 77.6%
4668964 604.9.1.0 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 0.65 50.0 4.84e-01 81.3% 77.6%
3596553 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.65 56.0 4.45e-01 100.0% 78.2%
5056430 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.65 46.0 4.81e-01 76.0% 91.4%
4955816 140.1.1.7 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_2 0.63 47.0 4.15e-01 78.7% 62.7%
5061688 5069.1.1.7 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 0.61 44.0 3.69e-01 78.7% 85.0%
3755118 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.61 45.0 3.97e-01 81.3% 81.7%
3593388 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 51.0 3.33e-01 94.7% 58.8%
4248372 1037.1.1.1 alpha bundles › Prolipoprotein diacylglyceryl transferase › Prolipoprotein diacylglyceryl transferase › Prolipoprotein diacylglyceryl transferase › LGT 0.60 44.0 2.96e-01 78.7% 30.5%
3515268 186.2.1.0 alpha arrays › lambda integrase-N-like › VEFS domain › VEFS domain 0.59 47.0 4.27e-01 88.0% 95.2%
3783238 5041.1.1.15 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › Tmemb_170 0.57 46.0 4.02e-01 88.0% 77.4%
4940854 2488.1.1.1 a/b three-layered sandwiches › alpha/beta knot › alpha/beta knot › alpha/beta knot › SpoU_methylase 0.57 43.0 3.01e-01 81.3% 35.7%
3459313 616.1.1.1 alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › Ribosomal_S15 0.56 40.0 3.83e-01 76.0% 74.4%
3242517 4009.1.1.3 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › KTI12 0.56 45.0 4.58e-01 86.7% 86.7%
4998579 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.54 46.0 3.51e-01 100.0% 91.3%
3616358 4009.1.1.0 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.54 43.0 4.51e-01 86.7% 92.9%
5039066 2488.1.1.1 a/b three-layered sandwiches › alpha/beta knot › alpha/beta knot › alpha/beta knot › SpoU_methylase 0.53 40.0 2.82e-01 81.3% 35.8%
3646270 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.52 39.0 3.97e-01 96.0% 78.7%
3744631 632.2.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains 0.52 38.0 3.92e-01 76.0% 82.9%
4969123 2488.1.1.1 a/b three-layered sandwiches › alpha/beta knot › alpha/beta knot › alpha/beta knot › SpoU_methylase 0.51 39.0 2.79e-01 84.0% 37.1%
4975796 4953.1.1.0 beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like 0.51 40.0 3.74e-01 88.0% 74.7%
3245209 103.1.1.0 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.50 37.0 4.09e-01 89.3% 98.3%
D6 medium residues 225-371
PDB
Domain cluster: representative
CATH (38)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2jgdB02 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.98 94.0 6.84e-01 100.0% 43.6%
6sy1A02 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.95 92.0 6.53e-01 100.0% 42.3%
1zu4A02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.71 49.0 4.32e-01 95.9% 48.2%
5l3qB02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.67 52.0 4.37e-01 95.9% 49.8%
4q6bA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.66 43.0 4.48e-01 93.2% 70.9%
5di3B00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.66 44.0 3.91e-01 85.0% 48.0%
3oesA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.65 43.0 4.24e-01 83.0% 61.8%
5ksoA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.63 43.0 4.19e-01 83.0% 62.0%
1ryhA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.62 39.0 3.77e-01 83.0% 54.4%
3t0qA00 3.40.850.10 Alpha Beta › 3-Layer(aba) Sandwich › Kinesin › Kinesin motor domain 0.62 56.0 4.42e-01 98.6% 97.0%
2rbgA00 3.40.50.11100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.61 41.0 4.42e-01 98.0% 80.6%
2bmjA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.61 39.0 3.75e-01 83.0% 54.6%
1u8zA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 41.0 4.00e-01 82.3% 61.8%
2clsA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 43.0 4.03e-01 85.0% 59.8%
1d5cA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 41.0 3.99e-01 81.6% 62.3%
3regA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 43.0 4.08e-01 83.0% 62.6%
1z06A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 42.0 4.09e-01 81.6% 64.2%
3c5cB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 42.0 4.00e-01 81.6% 62.3%
3w5jA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.59 41.0 3.73e-01 82.3% 53.6%
6mzoA01 3.40.50.11970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.59 39.0 4.20e-01 93.9% 79.4%
1z2aA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 40.0 3.90e-01 81.6% 64.0%
3vu9B00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 45.0 4.16e-01 95.2% 64.9%
2gj8D00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 42.0 4.04e-01 85.0% 66.3%
6jmgB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 41.0 3.89e-01 81.6% 63.0%
2nlkA02 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.57 49.0 4.02e-01 97.3% 51.9%
4qt4A00 3.40.50.1470 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Peptidyl-tRNA hydrolase 0.57 44.0 4.07e-01 81.6% 66.7%
3cioA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 49.0 4.11e-01 96.6% 60.0%
2qagB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 43.0 3.63e-01 84.4% 48.8%
3kzwA01 3.40.220.10 Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 0.55 43.0 4.25e-01 88.4% 78.5%
3bs4A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 47.0 4.02e-01 96.6% 57.6%
1wcv100 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 48.0 4.05e-01 96.6% 63.4%
2xtmA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 40.0 3.64e-01 83.0% 56.0%
6fgcA01 3.40.980.10 Alpha Beta › 3-Layer(aba) Sandwich › Molybdenum Cofactor Biosythetic Enzyme; Chain A › MoaB/Mog-like domain 0.53 40.0 3.78e-01 80.3% 79.0%
3d02A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 42.0 4.20e-01 96.6% 83.7%
2y27A02 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.52 28.0 3.29e-01 71.4% 74.8%
1mkzB00 3.40.980.10 Alpha Beta › 3-Layer(aba) Sandwich › Molybdenum Cofactor Biosythetic Enzyme; Chain A › MoaB/Mog-like domain 0.52 40.0 3.84e-01 81.6% 88.3%
1zunB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 41.0 3.74e-01 84.4% 73.7%
5tcdA01 3.40.720.10 Alpha Beta › 3-Layer(aba) Sandwich › Alkaline Phosphatase, subunit A › Alkaline Phosphatase, subunit A 0.51 45.0 3.58e-01 95.2% 53.9%
ECOD (84)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3946273 7574.1.1.0 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) 0.99 97.0 6.25e-01 100.0% 27.7%
4027848 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.98 96.0 6.35e-01 100.0% 32.2%
4532425 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.98 96.0 6.25e-01 100.0% 31.8%
4852210 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.97 95.0 6.40e-01 100.0% 34.2%
4442719 7574.1.1.14 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh+Transket_pyr 0.97 95.0 5.75e-01 100.0% 21.5%
3258899 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.97 94.0 6.45e-01 100.0% 36.2%
3723138 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.97 94.0 6.27e-01 100.0% 32.1%
3611613 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.97 94.0 6.22e-01 100.0% 30.9%
3897384 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.96 94.0 6.29e-01 100.0% 35.2%
4652217 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.96 94.0 6.31e-01 100.0% 33.0%
3703007 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.96 93.0 6.17e-01 100.0% 31.7%
3595923 7574.1.1.0 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) 0.95 93.0 6.18e-01 100.0% 32.7%
4554292 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.94 92.0 6.10e-01 100.0% 34.2%
3919594 7574.1.1.0 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) 0.94 89.0 7.38e-01 97.3% 67.2%
4199309 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.94 91.0 6.09e-01 100.0% 35.5%
3931753 2004.1.1.16 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Arf 0.64 39.0 3.72e-01 79.6% 50.3%
3995288 2004.1.1.16 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Arf 0.64 43.0 4.07e-01 83.7% 56.6%
None 0.64 51.0 3.89e-01 83.7% 40.9%
3774352 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.63 43.0 3.99e-01 84.4% 55.7%
4174475 2004.1.1.73 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.61 43.0 4.16e-01 82.3% 62.9%
5028425 2004.1.1.73 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.60 42.0 4.35e-01 83.0% 76.3%
3786027 2004.1.1.54 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Septin 0.60 48.0 3.84e-01 84.4% 47.8%
3273535 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.60 41.0 3.74e-01 82.3% 51.5%
3957958 7579.1.1.0 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases 0.60 34.0 3.60e-01 76.9% 60.8%
5052444 2004.1.1.16 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Arf 0.60 40.0 3.82e-01 83.7% 56.6%
3922917 2004.1.1.54 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Septin 0.60 48.0 3.58e-01 85.0% 70.0%
3254543 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.59 41.0 3.78e-01 82.3% 53.8%
4020791 2004.1.1.118 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 0.59 45.0 4.12e-01 83.7% 60.0%
None 0.59 47.0 3.84e-01 85.0% 48.9%
3409620 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.59 42.0 3.85e-01 83.0% 55.4%
3253475 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.59 42.0 3.71e-01 82.3% 50.2%
3514086 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.59 41.0 3.83e-01 83.0% 56.8%
3711821 2004.1.1.132 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DLIC 0.59 46.0 3.92e-01 83.0% 51.5%
3261865 2004.1.1.73 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.58 43.0 3.88e-01 81.6% 56.0%
5050657 2004.1.1.67 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › CbiA 0.58 51.0 4.30e-01 95.9% 59.6%
3887584 2004.1.1.118 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 0.58 41.0 2.93e-01 83.7% 24.0%
4009532 2004.1.1.73 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.58 42.0 3.45e-01 85.0% 40.4%
3915883 2004.1.1.118 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 0.58 44.0 3.03e-01 84.4% 23.2%
3903692 2004.1.1.118 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 0.57 42.0 3.90e-01 83.0% 57.9%
4025442 2004.1.1.16 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Arf 0.57 43.0 3.25e-01 83.0% 33.7%
3728046 2004.1.1.73 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.57 45.0 3.84e-01 83.0% 85.0%
4642902 2004.1.1.563 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1, PduV-EutP 0.57 41.0 3.96e-01 82.3% 65.5%
3855297 2004.1.1.118 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 0.57 43.0 3.83e-01 83.7% 54.0%
3270940 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.57 41.0 3.83e-01 82.3% 58.4%
4978236 2004.1.1.73 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.57 45.0 3.50e-01 83.0% 56.5%
3757760 2004.1.1.118 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 0.57 44.0 3.86e-01 83.7% 54.6%
3844846 2004.1.1.118 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 0.57 43.0 3.85e-01 84.4% 55.2%
3914056 2004.1.1.118 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 0.57 44.0 3.84e-01 85.0% 54.1%
3330912 2004.1.1.14 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › GTP_EFTU 0.57 45.0 3.97e-01 83.7% 70.2%
3934739 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.57 34.0 3.91e-01 86.4% 84.0%
3917579 2004.1.1.118 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 0.57 42.0 3.20e-01 85.0% 31.8%
3879061 2004.1.1.118 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 0.57 43.0 3.65e-01 83.0% 47.9%
5045290 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.56 43.0 3.93e-01 83.0% 60.0%
4249598 2004.1.1.73 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.56 40.0 3.87e-01 82.3% 63.5%
3918963 2004.1.1.118 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 0.56 42.0 3.35e-01 83.7% 37.4%
3917662 2004.1.1.118 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 0.56 42.0 3.04e-01 83.7% 26.9%
4374414 2004.1.1.54 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Septin 0.56 44.0 3.54e-01 85.0% 82.0%
3909100 2004.1.1.118 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 0.56 42.0 3.39e-01 84.4% 39.0%
4027421 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.56 44.0 4.09e-01 82.3% 85.6%
5037984 2004.1.1.73 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.55 40.0 3.86e-01 82.3% 67.1%
3499431 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.54 47.0 4.15e-01 94.6% 85.9%
4611584 2004.1.1.414 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › GTP_EFTU, MMR_HSR1 0.54 39.0 3.72e-01 82.3% 63.5%
3920857 2004.1.1.118 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 0.54 42.0 3.96e-01 84.4% 68.0%
3838532 327.9.1.0 a+b two layers › Alpha-lytic protease prodomain-like › Probable GTPase Der, C-terminal domain › Probable GTPase Der, C-terminal domain 0.54 38.0 2.73e-01 82.3% 23.6%
3204296 2004.1.1.54 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Septin 0.54 42.0 3.25e-01 82.3% 52.4%
4011930 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.54 42.0 3.29e-01 82.3% 56.5%
4041544 2004.1.1.73 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.54 40.0 3.68e-01 83.0% 59.5%
4639471 2004.1.1.73 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.54 42.0 3.96e-01 81.6% 82.3%
3194303 2004.1.1.54 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Septin 0.54 42.0 3.37e-01 82.3% 50.4%
3273060 2004.1.1.47 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › G-alpha 0.54 43.0 3.73e-01 85.0% 56.4%
None 0.53 38.0 2.66e-01 82.3% 23.6%
3192116 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.53 42.0 3.46e-01 83.0% 62.2%
3258300 2004.1.1.118 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 0.53 44.0 3.56e-01 91.8% 45.5%
4254001 2011.2.1.3 a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like › Pept_tRNA_hydro 0.53 43.0 3.95e-01 86.4% 66.3%
None 0.53 42.0 3.73e-01 85.0% 75.8%
3670862 2004.1.1.118 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 0.53 44.0 3.46e-01 89.1% 52.6%
3873738 2004.1.1.118 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 0.53 41.0 3.39e-01 83.7% 84.3%
3845616 2004.1.1.118 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 0.53 41.0 3.42e-01 83.0% 88.7%
4625556 2004.1.1.73 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.53 39.0 3.73e-01 83.0% 66.5%
4027323 2004.1.1.73 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.52 41.0 3.52e-01 83.0% 54.0%
None 0.51 41.0 3.69e-01 85.0% 95.1%
3607363 7529.1.1.0 a/b three-layered sandwiches › Macro domain-like › Macro domain-like › Macro domain-like 0.51 44.0 3.81e-01 95.2% 70.2%
5052305 2004.1.1.119 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Gtr1_RagA 0.51 40.0 3.79e-01 84.4% 82.6%
3252642 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.50 38.0 3.43e-01 83.0% 57.1%
D7 medium residues 612-804
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02779.30 best Transket_pyr 157.9 2.90e-46 91.2% 86.8%
CATH (52)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2jgdA03 3.40.50.12470 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.99 84.0 7.57e-01 99.0% 67.9%
7wgrA02 3.40.50.12470 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.97 90.0 7.87e-01 93.8% 77.4%
2ozlB01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.86 75.0 7.59e-01 99.0% 90.2%
2o1sA02 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.84 66.0 6.92e-01 99.5% 88.7%
4kxvA02 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.84 66.0 6.61e-01 99.5% 80.4%
1gpuA02 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.77 65.0 6.30e-01 99.5% 79.7%
1ybhA01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.76 63.0 6.28e-01 100.0% 84.1%
1powA01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.76 61.0 6.26e-01 97.4% 87.5%
4qq8A01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.76 61.0 6.30e-01 97.9% 89.0%
1pi3A01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.75 61.0 6.34e-01 98.4% 91.0%
2nxwA01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.73 57.0 5.94e-01 98.4% 86.7%
1ovmA03 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.70 55.0 5.66e-01 90.2% 84.6%
7pt4A01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.68 52.0 5.20e-01 87.6% 77.8%
1poxA03 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.66 53.0 5.42e-01 90.2% 85.3%
4y9tA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.60 40.0 4.18e-01 100.0% 72.7%
3jy6D02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.60 37.0 4.26e-01 99.5% 85.2%
2h3hA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.58 40.0 4.44e-01 100.0% 89.2%
1abeA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.58 40.0 4.61e-01 91.2% 98.6%
3k9cA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.58 37.0 4.23e-01 82.4% 87.2%
3c3kA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.58 36.0 4.17e-01 99.5% 87.0%
3brsA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.57 40.0 4.54e-01 89.1% 98.5%
2xauA03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 35.0 3.59e-01 75.6% 61.7%
3ctpA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.57 36.0 4.13e-01 98.4% 87.7%
4yv7A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.56 36.0 3.98e-01 92.2% 77.7%
1nrjB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 43.0 4.40e-01 81.3% 97.9%
2pueA03 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.55 37.0 4.15e-01 97.4% 87.8%
4tkzA00 3.40.50.510 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphotransferase system, mannose-type IIA component 0.55 37.0 4.27e-01 92.7% 98.5%
6jimB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 36.0 4.10e-01 80.8% 87.4%
4m9rB00 3.40.50.1460 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.54 43.0 4.09e-01 100.0% 71.3%
6nazA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 41.0 4.50e-01 82.4% 98.1%
2rjoA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.54 35.0 3.71e-01 92.2% 71.7%
3wdsA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.53 48.0 4.40e-01 100.0% 97.3%
2b99C00 3.40.50.960 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Lumazine/riboflavin synthase 0.53 40.0 4.42e-01 100.0% 98.7%
1bqcA00 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.53 44.0 3.85e-01 90.2% 91.4%
4impA02 3.40.50.11460 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.53 45.0 4.45e-01 100.0% 85.8%
3alfA01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.53 45.0 4.00e-01 91.2% 97.8%
3d7nA00 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.53 40.0 4.38e-01 82.4% 98.7%
8g3hA01 3.20.20.330 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Homocysteine-binding-like domain 0.52 45.0 3.95e-01 94.3% 95.4%
3l2oB02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 41.0 4.28e-01 82.4% 99.4%
1ryhA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 41.0 4.38e-01 83.4% 95.3%
1b0zA02 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.52 36.0 3.73e-01 90.7% 73.4%
2z5lA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 47.0 3.62e-01 100.0% 93.6%
1q7zA01 3.20.20.330 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Homocysteine-binding-like domain 0.52 47.0 4.09e-01 100.0% 98.3%
5lddC00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 41.0 4.31e-01 83.4% 97.6%
2yhaA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.51 34.0 3.92e-01 98.4% 92.1%
7ntgA01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.51 36.0 3.71e-01 95.9% 76.3%
3h5tA03 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.51 36.0 3.93e-01 99.0% 87.9%
4kq9A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.51 39.0 3.91e-01 100.0% 77.5%
4xjvA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.51 40.0 3.88e-01 83.4% 98.6%
3igfA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.50 46.0 4.19e-01 100.0% 88.4%
1itxA01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.50 46.0 3.80e-01 100.0% 94.5%
2a4aA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.50 41.0 3.78e-01 87.0% 92.8%
ECOD (61)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4442719 7574.1.1.14 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh+Transket_pyr 0.99 96.0 6.11e-01 98.4% 26.7%
3959979 7574.1.1.8 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Transket_pyr 0.99 95.0 7.61e-01 97.9% 59.1%
4001564 7574.1.1.8 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Transket_pyr 0.99 96.0 7.78e-01 98.4% 72.7%
3933130 7574.1.1.14 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh+Transket_pyr 0.99 96.0 6.03e-01 98.4% 26.4%
3600652 7574.1.1.0 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) 0.98 95.0 7.88e-01 97.4% 68.5%
3667621 7574.1.1.8 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Transket_pyr 0.98 93.0 7.69e-01 96.4% 74.4%
3607587 7574.1.1.8 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Transket_pyr 0.98 96.0 8.11e-01 99.0% 71.9%
3712681 7574.1.1.8 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Transket_pyr 0.97 83.0 8.41e-01 87.0% 100.0%
3592505 7574.1.1.0 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) 0.87 75.0 7.38e-01 99.0% 85.0%
3288635 7574.1.1.8 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Transket_pyr 0.86 74.0 7.50e-01 97.4% 89.5%
4197752 7574.1.1.8 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Transket_pyr 0.86 75.0 7.40e-01 98.4% 86.0%
3598677 7574.1.1.0 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) 0.86 75.0 7.44e-01 99.0% 86.5%
3737817 7574.1.1.8 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Transket_pyr 0.86 76.0 7.41e-01 99.5% 85.4%
4963535 7574.1.1.8 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Transket_pyr 0.85 75.0 7.50e-01 96.9% 89.7%
4559367 7574.1.1.8 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Transket_pyr 0.85 67.0 6.78e-01 98.4% 82.1%
4651760 7574.1.1.8 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Transket_pyr 0.84 66.0 6.80e-01 97.9% 83.8%
4457808 7574.1.1.8 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Transket_pyr 0.84 66.0 6.88e-01 97.9% 86.7%
4326273 7574.1.1.13 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Transket_pyr+DXP_synthase_N 0.84 66.0 4.77e-01 98.4% 32.2%
3953563 7574.1.1.8 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Transket_pyr 0.83 63.0 6.73e-01 99.0% 87.6%
3799585 7574.1.1.8 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Transket_pyr 0.83 65.0 6.52e-01 98.4% 79.0%
3381421 7574.1.1.8 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Transket_pyr 0.83 61.0 5.99e-01 100.0% 70.2%
4392995 7574.1.1.8 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Transket_pyr 0.83 63.0 6.73e-01 95.3% 88.8%
3284302 7574.1.1.8 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Transket_pyr 0.82 75.0 6.98e-01 97.4% 79.1%
4489486 7574.1.1.8 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Transket_pyr 0.80 75.0 7.27e-01 99.0% 89.0%
2392863 7574.1.1.7 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_N 0.76 62.0 6.13e-01 98.4% 81.1%
3305109 7574.1.1.8 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Transket_pyr 0.76 53.0 5.45e-01 98.4% 74.1%
4015790 7574.1.1.0 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) 0.74 61.0 6.22e-01 97.9% 88.1%
5005751 7574.1.1.7 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_N 0.74 61.0 6.30e-01 98.4% 91.1%
3968407 7574.1.1.9 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › XFP 0.74 65.0 6.32e-01 97.4% 84.3%
4456672 7574.1.1.9 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › XFP 0.74 68.0 6.43e-01 99.0% 83.1%
3283728 7574.1.1.5 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_C 0.73 55.0 5.60e-01 90.2% 78.9%
3188302 7574.1.1.9 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › XFP 0.73 67.0 6.24e-01 97.4% 79.6%
3602473 7574.1.1.5 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_C 0.73 55.0 5.85e-01 90.2% 88.2%
4876191 7574.1.1.5 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_C 0.73 53.0 5.74e-01 87.6% 88.8%
3284314 7574.1.1.2 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › E1_dh 0.72 65.0 5.31e-01 93.8% 71.5%
4028611 7574.1.1.13 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Transket_pyr+DXP_synthase_N 0.72 67.0 4.52e-01 98.4% 30.0%
4157073 7574.1.1.0 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) 0.70 56.0 5.61e-01 90.2% 81.5%
3187686 7574.1.1.0 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) 0.68 63.0 5.78e-01 100.0% 88.4%
4682602 7574.1.1.5 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_C 0.67 55.0 5.47e-01 91.2% 82.5%
4974376 7574.1.1.0 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) 0.66 53.0 5.20e-01 90.2% 77.1%
4942416 7574.1.1.1 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Transketolase_N 0.66 57.0 5.23e-01 90.7% 73.1%
3670409 7574.1.1.5 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_C 0.66 56.0 5.31e-01 90.7% 79.6%
3739463 7574.1.1.0 a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) 0.66 61.0 5.87e-01 100.0% 90.0%
4247326 2004.1.1.105 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinase-PPPase 0.61 33.0 4.18e-01 91.2% 91.4%
3895610 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.58 46.0 4.44e-01 82.9% 92.7%
3512874 2004.1.1.14 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › GTP_EFTU 0.57 51.0 4.75e-01 96.4% 97.1%
3840702 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.57 45.0 4.38e-01 82.4% 91.2%
3620417 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.57 45.0 4.41e-01 83.4% 95.7%
3733890 2003.1.11.1 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Formate/glycerate dehydrogenase catalytic domain-like › 2-Hacid_dh 0.55 41.0 4.37e-01 100.0% 89.1%
3798403 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.54 43.0 4.41e-01 82.9% 97.8%
4944358 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.54 42.0 4.55e-01 82.9% 97.6%
4434054 2004.1.1.523 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › URGCP_GTPase 0.53 42.0 3.57e-01 83.9% 67.9%
5001118 2004.1.1.16 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Arf 0.53 42.0 4.52e-01 97.9% 99.4%
3790157 2006.1.6.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.52 47.0 4.46e-01 99.0% 94.0%
8744 2002.1.1.96 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › S-methyl_trans 0.52 47.0 4.09e-01 100.0% 98.3%
5050327 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.52 41.0 4.13e-01 81.9% 86.8%
3498699 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.52 41.0 4.13e-01 83.4% 85.1%
4580130 2004.1.1.73 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.51 40.0 4.20e-01 83.4% 94.4%
4534207 2004.1.1.73 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.51 41.0 3.98e-01 82.9% 93.8%
3464712 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.51 40.0 4.04e-01 83.4% 89.2%
4971408 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.50 44.0 4.40e-01 100.0% 93.8%