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CAKLQF020000004.1__CAH1076763.1__SAMEA5780031_00992__00086

Bact-Vir

CAKLQF020000004.1__CAH1076763.1__SAMEA5780031_00992__00086

Identity

Kingdom:
phage

Quality

90.2 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 35-256
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02405.22 best MlaE 238.1 1.10e-70 96.0% 99.5%
CATH (24)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2oerA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.72 44.0 4.85e-01 97.3% 74.3%
2dg7A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.68 43.0 4.66e-01 95.5% 73.7%
4mk6A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.67 42.0 4.51e-01 100.0% 71.8%
3mnlB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.65 40.0 4.44e-01 94.6% 74.7%
1vi0A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.64 40.0 4.85e-01 96.4% 95.2%
1gqeA01 1.20.58.410 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor 0.61 26.0 3.55e-01 85.6% 75.2%
3kkdA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.60 42.0 4.49e-01 99.5% 79.8%
2lyiA01 1.10.274.60 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain 0.58 28.0 3.41e-01 79.3% 67.6%
3lwjA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.57 43.0 4.59e-01 100.0% 88.6%
4f4cA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.56 47.0 3.34e-01 89.6% 74.0%
2nwlC00 1.10.3860.10 Mainly Alpha › Orthogonal Bundle › Proton glutamate symport protein › Sodium:dicarboxylate symporter 0.56 45.0 3.68e-01 83.3% 84.6%
1uw4B00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.54 25.0 2.48e-01 91.0% 36.7%
5fglA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 43.0 4.51e-01 100.0% 92.0%
3rlfF04 1.10.3720.10 Mainly Alpha › Orthogonal Bundle › MetI-like fold › MetI-like 0.54 35.0 3.44e-01 95.0% 60.3%
7metA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.53 39.0 3.54e-01 74.3% 96.8%
3snhA02 1.20.120.1240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain 0.52 41.0 4.15e-01 80.2% 88.0%
5llmA00 1.10.3860.10 Mainly Alpha › Orthogonal Bundle › Proton glutamate symport protein › Sodium:dicarboxylate symporter 0.52 41.0 3.42e-01 83.8% 80.2%
1aepA00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.52 28.0 3.24e-01 84.2% 71.2%
2bl2A00 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.51 32.0 3.71e-01 75.2% 85.9%
2jbyA00 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.50 27.0 3.33e-01 87.8% 83.5%
4iu9B02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.50 36.0 3.75e-01 71.6% 94.6%
2ccyA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.50 28.0 3.56e-01 88.3% 92.1%
4p9fA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.50 32.0 3.97e-01 75.7% 100.0%
2onkC00 1.10.3720.10 Mainly Alpha › Orthogonal Bundle › MetI-like fold › MetI-like 0.50 37.0 3.61e-01 76.6% 70.2%
ECOD (65)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3979848 1075.1.1.22 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › MlaE 0.99 98.0 9.70e-01 100.0% 97.0%
4154209 1075.1.1.22 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › MlaE 0.98 86.0 8.54e-01 98.6% 86.1%
3957965 1075.1.1.22 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › MlaE 0.98 93.0 9.50e-01 97.3% 100.0%
3282320 1075.1.1.22 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › MlaE 0.97 95.0 8.82e-01 100.0% 83.4%
3972993 1075.1.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.97 94.0 9.17e-01 98.6% 92.8%
3829425 1075.1.1.22 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › MlaE 0.97 95.0 9.11e-01 100.0% 90.2%
3958909 1075.1.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.97 92.0 9.43e-01 97.3% 100.0%
3386556 1075.1.1.22 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › MlaE 0.97 95.0 8.91e-01 99.5% 86.7%
3284091 1075.1.2.24 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › MlaE 0.96 94.0 8.70e-01 100.0% 86.8%
3954305 1075.1.1.22 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › MlaE 0.95 93.0 8.62e-01 99.5% 86.4%
3282370 1075.1.1.22 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › MlaE 0.95 91.0 8.67e-01 98.6% 90.8%
3959628 1075.1.2.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain 0.93 66.0 7.89e-01 72.5% 100.0%
4979261 5079.1.1.1 alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE 0.75 52.0 5.71e-01 75.2% 85.2%
4975214 1075.1.1.3 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_2 0.73 68.0 6.10e-01 100.0% 90.2%
4977935 1075.1.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.72 66.0 6.43e-01 100.0% 88.6%
5032630 1075.1.1.3 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_2 0.72 64.0 6.27e-01 100.0% 87.1%
4974012 1075.1.1.3 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_2 0.72 67.0 6.13e-01 100.0% 86.1%
5018956 1075.1.1.12 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › CcmB 0.71 62.0 6.19e-01 100.0% 90.2%
5037011 1075.1.1.3 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_2 0.70 66.0 6.27e-01 100.0% 90.8%
5013354 1075.1.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.70 65.0 6.25e-01 100.0% 88.1%
4970353 1075.1.1.3 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_2 0.70 65.0 6.13e-01 100.0% 86.8%
3567090 5079.1.1.1 alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE 0.69 50.0 5.00e-01 84.2% 70.9%
3956898 1075.1.1.38 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › FLQE3_permease 0.69 58.0 5.76e-01 100.0% 83.4%
5047488 1075.1.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.69 59.0 5.73e-01 100.0% 82.8%
5009388 1075.1.1.3 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_2 0.69 64.0 6.01e-01 100.0% 83.3%
5075344 1075.1.1.3 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_2 0.68 63.0 6.00e-01 100.0% 91.5%
4119940 1075.1.1.65 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › DUF2705 0.67 61.0 5.89e-01 99.1% 86.0%
4955447 1075.1.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.67 61.0 5.86e-01 100.0% 86.0%
4959404 1075.1.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.64 60.0 5.66e-01 100.0% 87.9%
3280380 1075.1.1.28 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › PF30402 0.64 59.0 5.61e-01 100.0% 84.5%
4946745 1075.1.2.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain 0.64 51.0 5.47e-01 84.7% 97.4%
4606646 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.64 42.0 4.28e-01 79.7% 66.5%
4943717 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.62 56.0 4.88e-01 95.0% 85.8%
4997682 1075.5.1.8 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 0.61 37.0 3.83e-01 80.6% 61.9%
4955062 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.60 34.0 3.82e-01 75.2% 70.0%
4995294 1075.1.2.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain 0.60 46.0 5.03e-01 82.9% 97.3%
3719779 109.4.1.818 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › EXOC6_Sec15_N 0.59 41.0 2.86e-01 83.8% 22.0%
4962588 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.59 41.0 4.08e-01 77.0% 67.6%
4032097 1075.5.1.2 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ 0.59 51.0 4.58e-01 92.8% 77.0%
3280492 1075.3.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 0.57 36.0 3.52e-01 97.7% 57.0%
5057940 1075.5.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt 0.57 37.0 3.87e-01 79.7% 68.1%
5063387 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.57 50.0 4.80e-01 93.7% 85.5%
4996790 1075.5.1.8 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 0.57 51.0 4.78e-01 95.0% 83.4%
4202769 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.57 40.0 4.11e-01 82.0% 73.8%
3599645 1075.1.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_3 0.56 48.0 4.50e-01 100.0% 73.8%
5020613 1075.5.1.2 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ 0.56 49.0 4.70e-01 93.2% 85.5%
5058083 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.56 50.0 4.63e-01 95.5% 81.1%
4446544 1079.1.1.8 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › LysE 0.55 35.0 3.71e-01 75.2% 70.7%
5028176 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.55 49.0 4.57e-01 94.6% 80.7%
4936739 3921.1.1.1 alpha complex topology › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › Rnf-Nqr 0.55 38.0 4.03e-01 73.4% 76.4%
5025473 1075.5.1.8 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 0.55 49.0 4.56e-01 94.1% 80.7%
5038204 1075.5.1.8 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 0.55 50.0 4.62e-01 97.7% 85.3%
4952397 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.55 39.0 3.96e-01 82.4% 72.1%
4974561 1075.5.1.8 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 0.55 48.0 4.53e-01 93.7% 80.7%
5014653 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.55 41.0 4.15e-01 83.8% 77.3%
4950955 1075.5.1.2 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ 0.55 48.0 4.57e-01 93.2% 85.0%
4968080 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.54 47.0 4.47e-01 94.1% 82.2%
5056483 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.54 47.0 4.49e-01 94.1% 83.8%
5065783 1075.5.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt 0.53 47.0 4.43e-01 94.1% 82.2%
5063852 3921.1.1.1 alpha complex topology › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › Rnf-Nqr 0.53 33.0 3.48e-01 79.7% 67.5%
4996694 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.53 39.0 3.19e-01 75.2% 68.5%
3967503 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.53 45.0 4.38e-01 100.0% 81.2%
3283437 3615.1.1.0 alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain 0.53 41.0 3.54e-01 81.1% 59.4%
3589119 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.51 45.0 4.38e-01 96.8% 85.7%
3597541 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.50 35.0 3.35e-01 70.3% 86.4%