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CAKLQF020000004.1__CAH1076805.1__SAMEA5780031_01034__00128
Bact-VirCAKLQF020000004.1__CAH1076805.1__SAMEA5780031_01034__00128
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 195-304
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01594.23 best | AI-2E_transport | 62.9 | 4.80e-17 | 100.0% | 32.5% |
CATH (41)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1t72A02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.73 | 44.0 | 4.64e-01 | 89.1% | 67.3% |
| 2xq9A02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.69 | 44.0 | 4.30e-01 | 92.7% | 58.7% |
| 2ot4A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.67 | 49.0 | 4.98e-01 | 75.5% | 100.0% |
| 2wl8C00 | 1.20.120.900 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pex19, mPTS binding domain | 0.67 | 36.0 | 3.67e-01 | 80.9% | 51.4% |
| 1m5iA00 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.67 | 42.0 | 4.32e-01 | 90.9% | 65.7% |
| 2k3nA00 | 1.10.274.60 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain | 0.66 | 47.0 | 4.16e-01 | 73.6% | 58.7% |
| 2kj8A00 | 1.10.150.130 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain | 0.65 | 46.0 | 4.54e-01 | 73.6% | 75.4% |
| 1x04A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.65 | 45.0 | 3.77e-01 | 72.7% | 94.0% |
| 4jioA01 | 1.20.120.560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain | 0.64 | 45.0 | 4.02e-01 | 72.7% | 95.7% |
| 1h6gA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.63 | 39.0 | 3.85e-01 | 91.8% | 57.1% |
| 2k3oA00 | 1.10.274.60 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain | 0.62 | 47.0 | 4.47e-01 | 79.1% | 78.3% |
| 2zy9A03 | 1.10.357.20 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › SLC41 divalent cation transporters, integral membrane domain | 0.61 | 38.0 | 3.23e-01 | 96.4% | 39.1% |
| 4rflA02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.61 | 44.0 | 3.63e-01 | 75.5% | 74.9% |
| 2b5uA02 | 1.10.287.620 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins | 0.61 | 42.0 | 3.70e-01 | 99.1% | 47.8% |
| 2bnlC00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.60 | 47.0 | 4.48e-01 | 85.5% | 71.6% |
| 2qgaB01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.60 | 45.0 | 4.45e-01 | 79.1% | 98.2% |
| 1rj1A00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.60 | 44.0 | 4.02e-01 | 78.2% | 76.4% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.59 | 41.0 | 4.07e-01 | 72.7% | 81.2% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 42.0 | 4.34e-01 | 91.8% | 77.6% |
| 3caxA01 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.58 | 50.0 | 4.04e-01 | 94.5% | 61.3% |
| 4iu9B01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.58 | 52.0 | 4.15e-01 | 100.0% | 96.9% |
| 1u5kA02 | 1.20.1440.120 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Recombination protein O, C-terminal domain | 0.58 | 43.0 | 4.11e-01 | 77.3% | 100.0% |
| 3l1nA02 | 1.20.1280.140 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.58 | 32.0 | 3.55e-01 | 80.0% | 66.7% |
| 1t3dA01 | 1.10.3130.10 | Mainly Alpha › Orthogonal Bundle › serine acetyltransferase, domain 1 › serine acetyltransferase, domain 1 | 0.57 | 41.0 | 3.80e-01 | 73.6% | 85.0% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.57 | 44.0 | 4.42e-01 | 84.5% | 90.4% |
| 2vixA02 | 1.10.150.630 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › | 0.57 | 40.0 | 4.38e-01 | 86.4% | 92.1% |
| 3vprA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 43.0 | 3.97e-01 | 81.8% | 80.0% |
| 2q14B01 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.56 | 45.0 | 3.57e-01 | 88.2% | 53.6% |
| 1hw1A02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.55 | 38.0 | 3.41e-01 | 70.0% | 88.7% |
| 1u3dA02 | 1.25.40.80 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.55 | 38.0 | 3.57e-01 | 70.9% | 61.9% |
| 1dbhA01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.54 | 46.0 | 3.76e-01 | 92.7% | 68.7% |
| 1q2lA04 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.54 | 42.0 | 3.35e-01 | 82.7% | 51.8% |
| 1b0bA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.54 | 40.0 | 3.75e-01 | 79.1% | 78.0% |
| 1sqgA01 | 1.10.940.10 | Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like | 0.54 | 38.0 | 3.59e-01 | 74.5% | 59.6% |
| 2clbA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.53 | 46.0 | 4.06e-01 | 93.6% | 72.3% |
| 4nleA02 | 1.10.275.60 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › | 0.53 | 38.0 | 3.64e-01 | 78.2% | 63.6% |
| 4etrB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.52 | 40.0 | 3.93e-01 | 86.4% | 75.4% |
| 1pw4A02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.52 | 44.0 | 3.62e-01 | 95.5% | 87.7% |
| 3pwxA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.52 | 45.0 | 3.86e-01 | 98.2% | 77.2% |
| 2c42A06 | 3.40.50.970 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains | 0.52 | 41.0 | 2.84e-01 | 86.4% | 29.4% |
| 2wbiB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.50 | 44.0 | 3.99e-01 | 100.0% | 84.2% |
ECOD (62)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3602989 | 5054.1.1.68 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › AI-2E_transport | 0.93 | 89.0 | 6.54e-01 | 100.0% | 43.9% |
| 5016189 | 5054.1.1.68 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › AI-2E_transport | 0.91 | 86.0 | 6.26e-01 | 100.0% | 43.3% |
| 5018340 | 5054.1.1.68 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › AI-2E_transport | 0.90 | 85.0 | 6.13e-01 | 100.0% | 40.0% |
| 4048768 | 5054.1.1.68 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › AI-2E_transport | 0.90 | 85.0 | 6.09e-01 | 100.0% | 39.6% |
| 5035991 | 3567.1.1.112 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › AI-2E_transport | 0.90 | 85.0 | 7.32e-01 | 100.0% | 70.6% |
| 4957839 | 5069.1.3.130 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › AI-2E_transport | 0.89 | 84.0 | 6.13e-01 | 100.0% | 42.6% |
| 4953656 | 5054.1.1.68 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › AI-2E_transport | 0.89 | 84.0 | 7.24e-01 | 100.0% | 69.4% |
| 4005919 | 5054.1.1.68 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › AI-2E_transport | 0.88 | 83.0 | 5.99e-01 | 100.0% | 50.4% |
| 4496831 | 3755.4.1.49 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › AI-2E_transport | 0.88 | 83.0 | 6.10e-01 | 100.0% | 43.1% |
| 4603896 | 1075.4.1.38 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › AI-2E_transport | 0.87 | 82.0 | 5.82e-01 | 100.0% | 50.0% |
| 3942099 | 605.1.1.209 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › AI-2E_transport | 0.86 | 74.0 | 7.79e-01 | 90.9% | 100.0% |
| 3588155 | 1075.4.1.38 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › AI-2E_transport | 0.86 | 81.0 | 5.61e-01 | 100.0% | 35.6% |
| 5006067 | 5054.1.1.68 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › AI-2E_transport | 0.86 | 80.0 | 5.91e-01 | 100.0% | 43.8% |
| 4008134 | 5054.1.1.68 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › AI-2E_transport | 0.86 | 80.0 | 5.97e-01 | 100.0% | 44.3% |
| 3589352 | 192.2.1.50 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › AI-2E_transport | 0.86 | 80.0 | 5.89e-01 | 100.0% | 43.0% |
| 4457750 | 3567.1.1.112 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › AI-2E_transport | 0.85 | 76.0 | 7.62e-01 | 93.6% | 100.0% |
| 3283708 | 1075.4.1.38 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › AI-2E_transport | 0.85 | 79.0 | 5.95e-01 | 100.0% | 44.8% |
| 5014863 | 3755.3.1.524 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › AI-2E_transport | 0.85 | 79.0 | 5.56e-01 | 100.0% | 48.7% |
| 3988246 | 5054.1.1.68 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › AI-2E_transport | 0.85 | 79.0 | 5.52e-01 | 100.0% | 34.8% |
| 5053975 | 5054.1.1.68 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › AI-2E_transport | 0.83 | 77.0 | 5.56e-01 | 100.0% | 38.9% |
| 3986989 | 5054.1.1.68 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › AI-2E_transport | 0.82 | 76.0 | 6.50e-01 | 100.0% | 95.3% |
| 3590978 | 102.1.2.30 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › DNA-glycosylase › AI-2E_transport | 0.82 | 75.0 | 5.50e-01 | 100.0% | 51.1% |
| 3294533 | 4953.1.1.0 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like | 0.80 | 72.0 | 6.28e-01 | 96.4% | 87.5% |
| 3240315 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.76 | 47.0 | 4.98e-01 | 94.5% | 69.0% |
| 4964311 | 5039.1.1.2 ↗ | alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › DUF420 | 0.72 | 42.0 | 3.52e-01 | 85.5% | 35.0% |
| 4296017 | 632.22.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA | 0.72 | 51.0 | 4.84e-01 | 73.6% | 93.8% |
| 5017720 | 2484.1.1.199 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Transposase_mut | 0.70 | 45.0 | 3.50e-01 | 73.6% | 30.4% |
| 4026102 | 592.1.1.1 ↗ | alpha arrays › PWI domain-like › PWI domain › PWI domain › PWI | 0.68 | 45.0 | 5.21e-01 | 73.6% | 97.3% |
| 3905988 | 4982.1.1.4 ↗ | alpha arrays › KaiA/RbsU domain-like › KaiA/RbsU domain › KaiA/RbsU domain › SYS1 | 0.68 | 48.0 | 4.55e-01 | 90.9% | 61.5% |
| 4465966 | 632.11.1.10 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like › EzrA | 0.68 | 48.0 | 4.60e-01 | 74.5% | 94.6% |
| 4952530 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.67 | 42.0 | 3.98e-01 | 90.0% | 51.9% |
| 5070606 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.65 | 49.0 | 4.59e-01 | 79.1% | 97.8% |
| 4011174 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.65 | 55.0 | 5.68e-01 | 97.3% | 100.0% |
| 3972434 | 604.5.1.33 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › FUSC | 0.65 | 50.0 | 4.47e-01 | 81.8% | 94.8% |
| 5014639 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.63 | 41.0 | 4.25e-01 | 93.6% | 71.0% |
| 4085606 | 632.22.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA | 0.63 | 43.0 | 4.40e-01 | 94.5% | 70.9% |
| 5016669 | 604.39.1.0 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters | 0.62 | 45.0 | 3.82e-01 | 75.5% | 74.6% |
| 3609403 | 1189.1.1.1 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › Trypan_glycop | 0.62 | 51.0 | 3.50e-01 | 88.2% | 91.3% |
| 3423128 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.58 | 46.0 | 4.25e-01 | 89.1% | 82.0% |
| 3989633 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 39.0 | 3.02e-01 | 70.0% | 47.5% |
| 3711200 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.57 | 49.0 | 3.25e-01 | 95.5% | 39.6% |
| 3929481 | 109.49.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Helical domain in acetyl-CoA carboxylase › Helical domain in acetyl-CoA carboxylase › ACC_central | 0.56 | 44.0 | 3.44e-01 | 84.5% | 60.8% |
| 3502455 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.56 | 51.0 | 4.08e-01 | 100.0% | 62.4% |
| 4138073 | 1002.1.1.1 ↗ | alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB | 0.56 | 42.0 | 4.00e-01 | 79.1% | 87.7% |
| 3964217 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.56 | 45.0 | 3.48e-01 | 88.2% | 76.1% |
| 3367930 | 1002.1.1.1 ↗ | alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB | 0.55 | 42.0 | 3.70e-01 | 79.1% | 74.4% |
| 4208599 | 1002.1.1.1 ↗ | alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB | 0.55 | 41.0 | 3.94e-01 | 78.2% | 88.5% |
| 4097792 | 1002.1.1.1 ↗ | alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB | 0.55 | 41.0 | 3.93e-01 | 77.3% | 91.2% |
| 3447070 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.55 | 48.0 | 4.62e-01 | 97.3% | 96.2% |
| 4982649 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.55 | 47.0 | 3.90e-01 | 91.8% | 92.6% |
| 4359404 | 1002.1.1.1 ↗ | alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB | 0.55 | 41.0 | 3.93e-01 | 78.2% | 88.5% |
| 4393414 | 1002.1.1.1 ↗ | alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB | 0.55 | 40.0 | 3.91e-01 | 77.3% | 89.5% |
| 4680489 | 1002.1.1.1 ↗ | alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB | 0.55 | 41.0 | 3.96e-01 | 78.2% | 88.8% |
| 3593589 | 1128.1.1.0 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein | 0.54 | 38.0 | 3.63e-01 | 70.9% | 93.6% |
| 3969002 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.54 | 47.0 | 3.96e-01 | 96.4% | 92.6% |
| 3735343 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.54 | 47.0 | 3.75e-01 | 98.2% | 92.8% |
| 3988314 | 1002.1.1.4 ↗ | alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › ThrE_2 | 0.54 | 38.0 | 3.59e-01 | 75.5% | 70.8% |
| 4598975 | 1002.1.1.0 ↗ | alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel | 0.54 | 41.0 | 4.14e-01 | 80.9% | 94.7% |
| 5024553 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.53 | 47.0 | 4.00e-01 | 98.2% | 97.2% |
| 3822894 | 109.4.1.2392 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › F-box | 0.53 | 38.0 | 3.50e-01 | 74.5% | 58.6% |
| 3235605 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.52 | 42.0 | 3.26e-01 | 87.3% | 74.8% |
| 3593820 | 1002.1.1.0 ↗ | alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel | 0.50 | 37.0 | 3.74e-01 | 79.1% | 95.7% |