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CAKLQF020000005.1__CAH1077933.1__SAMEA5780031_01166__00014
Bact-VirCAKLQF020000005.1__CAH1077933.1__SAMEA5780031_01166__00014
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 75-219_251-265
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03553.22 best | Na_H_antiporter | 32.3 | 8.90e-08 | 52.5% | 23.8% |
CATH (24)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4huqS00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.62 | 43.0 | 4.28e-01 | 90.6% | 67.7% |
| 5tgtA02 | 1.10.10.350 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.61 | 33.0 | 3.74e-01 | 100.0% | 67.5% |
| 3u8vA00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.60 | 31.0 | 4.23e-01 | 99.4% | 97.6% |
| 3kavA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.59 | 29.0 | 3.48e-01 | 75.0% | 69.6% |
| 4dveA00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.59 | 45.0 | 4.32e-01 | 90.6% | 68.3% |
| 3wscA00 | 1.20.1420.20 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › M75 peptidase, HXXE motif | 0.58 | 48.0 | 4.15e-01 | 89.4% | 81.7% |
| 6todA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.57 | 43.0 | 3.52e-01 | 78.1% | 85.6% |
| 4g12A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 46.0 | 4.72e-01 | 90.6% | 92.6% |
| 3owaA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.56 | 39.0 | 4.17e-01 | 87.5% | 82.6% |
| 3snhA02 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.56 | 41.0 | 3.74e-01 | 95.6% | 56.5% |
| 3l39A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.56 | 40.0 | 3.75e-01 | 74.4% | 100.0% |
| 4ecgA00 | 1.20.1420.20 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › M75 peptidase, HXXE motif | 0.55 | 45.0 | 3.52e-01 | 88.7% | 82.6% |
| 1m2vB01 | 1.20.120.730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Sec23/Sec24 helical domain | 0.54 | 38.0 | 3.73e-01 | 100.0% | 66.9% |
| 8h4pA01 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.53 | 43.0 | 3.55e-01 | 87.5% | 50.3% |
| 1ug7A00 | 1.20.120.360 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Axin interactor, dorsalization-associated protein, N-terminal domain | 0.52 | 33.0 | 3.68e-01 | 78.8% | 79.7% |
| 2id6A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 43.0 | 4.42e-01 | 90.6% | 92.9% |
| 4g10A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.51 | 38.0 | 4.10e-01 | 94.4% | 89.7% |
| 1ileA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.51 | 38.0 | 3.56e-01 | 100.0% | 63.9% |
| 8h8jC01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.51 | 39.0 | 3.30e-01 | 90.6% | 47.6% |
| 3nrhA00 | 1.20.120.1550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Protein of unknown function DUF5063 | 0.51 | 39.0 | 4.01e-01 | 91.3% | 82.3% |
| 4rajA00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.50 | 38.0 | 3.48e-01 | 78.8% | 84.3% |
| 1sxjE03 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.50 | 31.0 | 3.78e-01 | 91.3% | 99.0% |
| 6i9kA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.50 | 40.0 | 3.22e-01 | 90.6% | 43.2% |
| 3iqcA00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.50 | 33.0 | 3.72e-01 | 100.0% | 88.2% |
ECOD (29)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3963976 | 3355.1.1.8 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_H_antiporter | 0.87 | 85.0 | 5.83e-01 | 100.0% | 36.3% |
| 3971875 | 3355.1.1.0 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter | 0.84 | 81.0 | 5.67e-01 | 100.0% | 38.0% |
| 3839299 | 3355.1.1.8 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_H_antiporter | 0.83 | 78.0 | 5.51e-01 | 100.0% | 36.9% |
| 4030857 | 3355.1.1.16 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › DcuC | 0.75 | 57.0 | 4.11e-01 | 90.6% | 28.6% |
| 3976407 | 3355.1.1.4 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › DctM | 0.68 | 58.0 | 4.21e-01 | 90.6% | 98.1% |
| 4994403 | 109.3.1.480 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Na_H_antiporter | 0.67 | 51.0 | 5.37e-01 | 90.6% | 89.0% |
| 3502277 | 3355.1.1.1 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_sulph_symp | 0.65 | 60.0 | 4.19e-01 | 100.0% | 34.1% |
| 3163671 | 3355.1.1.11 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › GntP_permease | 0.64 | 52.0 | 3.87e-01 | 100.0% | 33.3% |
| 5014566 | 3355.1.1.4 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › DctM | 0.64 | 53.0 | 3.92e-01 | 88.7% | 84.1% |
| 5014453 | 1075.1.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain | 0.61 | 45.0 | 4.56e-01 | 90.6% | 78.1% |
| 3330299 | 4070.1.1.4 ↗ | alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like › Peptidase_M50B | 0.57 | 42.0 | 3.80e-01 | 76.9% | 96.9% |
| 5060515 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.56 | 42.0 | 3.76e-01 | 77.5% | 66.2% |
| 5065168 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.56 | 41.0 | 3.97e-01 | 77.5% | 69.7% |
| 4497291 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.55 | 41.0 | 3.55e-01 | 76.2% | 60.8% |
| 4003906 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.55 | 41.0 | 4.51e-01 | 78.1% | 100.0% |
| 3744662 | 604.5.1.8 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › ArAE_2 | 0.55 | 41.0 | 3.88e-01 | 79.4% | 100.0% |
| 5063888 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.54 | 40.0 | 3.65e-01 | 77.5% | 67.4% |
| 5073876 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.54 | 32.0 | 2.31e-01 | 85.0% | 19.6% |
| 3228529 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.54 | 40.0 | 4.12e-01 | 76.9% | 98.7% |
| 3218716 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.54 | 39.0 | 4.11e-01 | 75.0% | 100.0% |
| 3212831 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.53 | 40.0 | 3.90e-01 | 80.0% | 85.4% |
| 3680258 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.53 | 39.0 | 3.56e-01 | 76.9% | 66.4% |
| 3973147 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.53 | 38.0 | 3.60e-01 | 73.1% | 98.4% |
| 3503653 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.52 | 39.0 | 3.18e-01 | 78.1% | 81.6% |
| 3507361 | 5001.1.1.60 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srx | 0.52 | 47.0 | 3.75e-01 | 98.1% | 62.9% |
| 3936174 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.52 | 40.0 | 3.20e-01 | 81.2% | 76.4% |
| 3596751 | 1075.4.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold | 0.51 | 45.0 | 3.47e-01 | 94.4% | 76.6% |
| 3385850 | 1075.5.1.2 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ | 0.51 | 41.0 | 3.62e-01 | 85.6% | 92.9% |
| 3292475 | 5001.1.1.32 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Solute_trans_a | 0.51 | 43.0 | 3.58e-01 | 90.6% | 66.4% |
D2
medium
residues 1-52
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF13726.13 best | Na_H_antiport_2 | 60.8 | 1.60e-16 | 98.1% | 58.6% |
CATH (63)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2qhpA00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.91 | 64.0 | 3.83e-01 | 73.1% | 85.4% |
| 4e84B00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.90 | 61.0 | 3.67e-01 | 71.2% | 77.7% |
| 6ilsA00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.89 | 62.0 | 3.71e-01 | 73.1% | 79.8% |
| 2hlzA00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.87 | 61.0 | 3.69e-01 | 73.1% | 12.8% |
| 2aplA01 | 1.10.8.330 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › PG0816-like | 0.87 | 59.0 | 5.34e-01 | 71.2% | 54.4% |
| 4e69A00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.86 | 60.0 | 3.63e-01 | 73.1% | 83.2% |
| 1z2iA01 | 1.10.1530.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 › Malate/L-lactate/L-sulpholactate dehydrogenase, four-helix barrel | 0.86 | 61.0 | 4.95e-01 | 75.0% | 41.9% |
| 1rfmA01 | 1.10.1530.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 › Malate/L-lactate/L-sulpholactate dehydrogenase, four-helix barrel | 0.83 | 59.0 | 4.31e-01 | 75.0% | 29.5% |
| 3ktnA00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.82 | 59.0 | 3.53e-01 | 76.9% | 85.3% |
| 2g8yA01 | 1.10.1530.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 › Malate/L-lactate/L-sulpholactate dehydrogenase, four-helix barrel | 0.81 | 57.0 | 4.41e-01 | 75.0% | 34.5% |
| 2q0yA01 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.80 | 56.0 | 4.03e-01 | 73.1% | 29.0% |
| 6m36O01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.80 | 62.0 | 5.01e-01 | 84.6% | 75.0% |
| 3of4A00 | 3.40.109.10 | Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase | 0.79 | 55.0 | 3.61e-01 | 73.1% | 19.3% |
| 4m5bA00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.79 | 71.0 | 4.63e-01 | 100.0% | 42.5% |
| 4gm6A00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.78 | 62.0 | 3.67e-01 | 84.6% | 88.1% |
| 2c5qA00 | 3.50.30.40 | Alpha Beta › 3-Layer(bba) Sandwich › Glucose Oxidase; domain 1 › Ribonuclease E inhibitor RraA/RraA-like | 0.77 | 52.0 | 3.32e-01 | 82.7% | 15.9% |
| 1dcnA03 | 1.10.40.30 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) | 0.76 | 52.0 | 4.65e-01 | 76.9% | 51.4% |
| 2x3mA00 | 1.25.40.670 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.76 | 65.0 | 4.47e-01 | 94.2% | 86.1% |
| 2afbB00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.76 | 60.0 | 3.57e-01 | 84.6% | 88.0% |
| 4h8aB01 | 1.10.1530.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 › Malate/L-lactate/L-sulpholactate dehydrogenase, four-helix barrel | 0.75 | 53.0 | 5.12e-01 | 75.0% | 65.0% |
| 7vtgA01 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.75 | 59.0 | 3.57e-01 | 84.6% | 88.1% |
| 1ynbA00 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.74 | 60.0 | 4.10e-01 | 86.5% | 41.3% |
| 1un8A02 | 1.25.40.340 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › DhaL domain | 0.74 | 65.0 | 4.40e-01 | 100.0% | 35.9% |
| 4o1gA00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.74 | 58.0 | 3.48e-01 | 84.6% | 80.2% |
| 1ss3A00 | 1.10.287.720 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Pollen allergen ole e 6 | 0.73 | 49.0 | 5.02e-01 | 78.8% | 72.0% |
| 1yqgA02 | 1.10.3730.10 | Mainly Alpha › Orthogonal Bundle › ProC C-terminal domain-like fold › ProC C-terminal domain-like | 0.73 | 50.0 | 3.84e-01 | 71.2% | 35.4% |
| 1vibA00 | 1.10.287.120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Neurotoxin B-IV-like | 0.73 | 50.0 | 4.99e-01 | 73.1% | 74.5% |
| 2c4eA00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.73 | 56.0 | 3.44e-01 | 84.6% | 86.6% |
| 3ci0K02 | 1.10.40.60 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › EpsJ-like | 0.72 | 56.0 | 4.37e-01 | 86.5% | 48.7% |
| 3triA02 | 1.10.3730.10 | Mainly Alpha › Orthogonal Bundle › ProC C-terminal domain-like fold › ProC C-terminal domain-like | 0.71 | 52.0 | 4.11e-01 | 76.9% | 38.8% |
| 1fc3B00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.70 | 58.0 | 4.81e-01 | 98.1% | 57.4% |
| 3ie7A00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.70 | 64.0 | 3.88e-01 | 100.0% | 86.1% |
| 3vayA02 | 1.20.120.1600 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.69 | 56.0 | 4.88e-01 | 98.1% | 71.3% |
| 3sk9A00 | 1.10.3210.30 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › | 0.68 | 57.0 | 3.66e-01 | 90.4% | 20.9% |
| 1rr7A01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.67 | 44.0 | 4.68e-01 | 75.0% | 76.1% |
| 3kzhB00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.67 | 59.0 | 3.61e-01 | 100.0% | 85.4% |
| 4jndA01 | 1.10.1740.220 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › | 0.67 | 52.0 | 3.87e-01 | 84.6% | 68.5% |
| 4s1hA00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.67 | 60.0 | 3.70e-01 | 100.0% | 92.0% |
| 2h9dD00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.67 | 46.0 | 3.76e-01 | 75.0% | 38.0% |
| 2om6A02 | 1.10.150.400 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › | 0.66 | 55.0 | 4.90e-01 | 98.1% | 64.6% |
| 3ibyD02 | 1.10.287.1770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.65 | 56.0 | 4.75e-01 | 94.2% | 86.9% |
| 4irfB00 | 1.10.1780.10 | Mainly Alpha › Orthogonal Bundle › Double Clp-N motif › Clp, N-terminal domain | 0.64 | 50.0 | 3.62e-01 | 86.5% | 30.6% |
| 3mbhA00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.64 | 57.0 | 3.54e-01 | 100.0% | 93.4% |
| 2nwhA00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.64 | 56.0 | 3.43e-01 | 98.1% | 86.0% |
| 3bf5A01 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.64 | 53.0 | 3.42e-01 | 92.3% | 93.3% |
| 2abqA00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.64 | 56.0 | 3.47e-01 | 100.0% | 20.3% |
| 3o8jA02 | 1.10.230.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450-Terp; domain 2 › Cytochrome P450-Terp, domain 2 | 0.63 | 41.0 | 3.35e-01 | 92.3% | 35.4% |
| 2ddmB00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.63 | 54.0 | 3.45e-01 | 100.0% | 87.8% |
| 1ug7A00 | 1.20.120.360 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Axin interactor, dorsalization-associated protein, N-terminal domain | 0.63 | 46.0 | 3.53e-01 | 80.8% | 56.2% |
| 1j09A05 | 1.10.10.350 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.63 | 43.0 | 3.55e-01 | 73.1% | 49.0% |
| 1ku9B01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.62 | 53.0 | 4.58e-01 | 100.0% | 59.8% |
| 3nqxA02 | 1.10.390.10 | Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2 | 0.62 | 48.0 | 3.61e-01 | 98.1% | 32.2% |
| 2w3sB02 | 3.30.365.10 | Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain | 0.61 | 51.0 | 3.67e-01 | 98.1% | 82.6% |
| 3rmiA00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.61 | 43.0 | 3.52e-01 | 76.9% | 38.1% |
| 3b4qA00 | 1.10.1200.100 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › conserved protein domain from corynebacterium diphtheriae | 0.61 | 49.0 | 4.30e-01 | 96.2% | 72.4% |
| 3v5uA01 | 6.10.280.80 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region | 0.61 | 42.0 | 3.68e-01 | 73.1% | 93.4% |
| 5ts9B00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.59 | 44.0 | 3.24e-01 | 84.6% | 76.4% |
| 1b0bA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.59 | 40.0 | 3.10e-01 | 73.1% | 29.1% |
| 2jifA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.59 | 48.0 | 3.46e-01 | 90.4% | 75.3% |
| 4chgA00 | 3.40.50.1010 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease | 0.56 | 44.0 | 3.34e-01 | 84.6% | 33.1% |
| 3h49B00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.55 | 45.0 | 2.90e-01 | 100.0% | 93.0% |
| 2x26A01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.54 | 45.0 | 3.17e-01 | 98.1% | 74.6% |
| 1irxA05 | 1.10.10.350 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.54 | 43.0 | 3.73e-01 | 98.1% | 62.4% |
ECOD (59)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3810884 | 621.1.1.3 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB | 0.94 | 66.0 | 4.59e-01 | 73.1% | 27.6% |
| 3163671 | 3355.1.1.11 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › GntP_permease | 0.94 | 88.0 | 5.04e-01 | 100.0% | 12.5% |
| 4582471 | 3355.1.1.11 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › GntP_permease | 0.91 | 83.0 | 4.76e-01 | 100.0% | 12.6% |
| 3632302 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.88 | 62.0 | 5.23e-01 | 73.1% | 47.5% |
| 3649222 | 2004.1.1.23 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom | 0.87 | 61.0 | 3.57e-01 | 73.1% | 11.3% |
| 4982432 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.86 | 62.0 | 5.39e-01 | 75.0% | 54.7% |
| 4012810 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.86 | 60.0 | 4.99e-01 | 73.1% | 47.1% |
| 4981035 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.86 | 60.0 | 5.51e-01 | 73.1% | 61.5% |
| 5071140 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.86 | 60.0 | 4.17e-01 | 73.1% | 26.0% |
| 3833866 | 2004.1.1.24 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom,Helicase_C | 0.85 | 59.0 | 3.21e-01 | 73.1% | 5.1% |
| 5072602 | 225.1.1.6 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_2 | 0.85 | 68.0 | 4.90e-01 | 84.6% | 76.2% |
| 3244718 | 103.4.1.0 ↗ | alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein | 0.84 | 59.0 | 4.91e-01 | 73.1% | 44.7% |
| 3588797 | 4084.1.1.0 ↗ | alpha bundles › ChaB-like › ChaB-like › ChaB-like | 0.84 | 57.0 | 5.26e-01 | 71.2% | 56.9% |
| 3334228 | 5076.1.1.1 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr | 0.83 | 75.0 | 4.65e-01 | 100.0% | 43.9% |
| 4411911 | 198.2.1.3 ↗ | alpha arrays › Saposin-like › Bacteriocin AS-48-related › Bacteriocin AS-48-related › SseC | 0.83 | 56.0 | 4.08e-01 | 71.2% | 27.4% |
| 3984466 | 2003.6.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Ribokinase-like › Ribokinase-like › PfkB | 0.82 | 57.0 | 3.69e-01 | 73.1% | 18.1% |
| 3925650 | 5076.1.1.1 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr | 0.81 | 72.0 | 4.47e-01 | 100.0% | 36.5% |
| 3735660 | 2004.1.1.499 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD_2, Helicase_C_2 | 0.81 | 59.0 | 3.25e-01 | 76.9% | 43.2% |
| 3482541 | 5076.1.1.1 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr | 0.80 | 72.0 | 4.50e-01 | 100.0% | 35.6% |
| 4351255 | 191.1.1.91 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › PF29842 | 0.79 | 63.0 | 5.13e-01 | 84.6% | 83.3% |
| 4560524 | 2498.1.1.9 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M1 | 0.78 | 61.0 | 3.77e-01 | 84.6% | 69.8% |
| 4987541 | 611.8.1.0 ↗ | alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 | 0.76 | 53.0 | 4.16e-01 | 73.1% | 37.3% |
| 4635506 | 230.3.1.1 ↗ | a+b two layers › T-fold › Elongation factor Ts (EF-Ts), dimerisation domain › Elongation factor Ts (EF-Ts), dimerisation domain › EF_TS | 0.75 | 53.0 | 3.84e-01 | 75.0% | 38.6% |
| 4149 | 590.1.1.1 ↗ | alpha bundles › Citrobacter dihydroxyacetone kinase extra ATP-binding domain › Citrobacter dihydroxyacetone kinase extra ATP-binding domain › Citrobacter dihydroxyacetone kinase extra ATP-binding domain › Dak2 | 0.74 | 65.0 | 4.32e-01 | 100.0% | 33.3% |
| 4065157 | 2005.1.1.25 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › HIGH_NTase1 | 0.74 | 64.0 | 3.76e-01 | 94.2% | 13.5% |
| 3973020 | 1197.1.1.0 ↗ | alpha bundles › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY | 0.74 | 65.0 | 4.43e-01 | 98.1% | 31.7% |
| 5032477 | 129.1.1.15 ↗ | alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › P5CR_dimer | 0.74 | 54.0 | 4.16e-01 | 76.9% | 36.4% |
| 2407303 | 2005.1.1.25 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › HIGH_NTase1 | 0.73 | 63.0 | 3.88e-01 | 94.2% | 17.8% |
| 4190432 | 1197.1.1.1 ↗ | alpha bundles › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › G3P_acyltransf | 0.73 | 63.0 | 4.30e-01 | 98.1% | 31.4% |
| 3455488 | 2006.1.4.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like | 0.73 | 49.0 | 4.76e-01 | 71.2% | 61.7% |
| 4106875 | 2005.1.1.25 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › HIGH_NTase1 | 0.73 | 61.0 | 3.60e-01 | 94.2% | 12.0% |
| 3688172 | 2004.1.1.73 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 | 0.72 | 61.0 | 3.60e-01 | 100.0% | 40.0% |
| 3202292 | 101.38.1.3 ↗ | alpha arrays › HTH › DNA-binding domain of the replication initiator protein ColE2-Rep › DNA-binding domain of the replication initiator protein ColE2-Rep › DUF6891 | 0.71 | 57.0 | 5.16e-01 | 98.1% | 65.7% |
| 5060609 | 632.8.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 | 0.71 | 49.0 | 4.35e-01 | 73.1% | 70.7% |
| 4547786 | 3236.1.1.12 ↗ | alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Cons_hypoth698 | 0.70 | 63.0 | 3.82e-01 | 100.0% | 45.7% |
| 5082058 | 164.1.1.1 ↗ | alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › CM_2 | 0.70 | 48.0 | 4.33e-01 | 73.1% | 56.0% |
| 4060628 | 230.3.1.1 ↗ | a+b two layers › T-fold › Elongation factor Ts (EF-Ts), dimerisation domain › Elongation factor Ts (EF-Ts), dimerisation domain › EF_TS | 0.70 | 49.0 | 3.71e-01 | 75.0% | 40.8% |
| 4990523 | 129.1.1.15 ↗ | alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › P5CR_dimer | 0.69 | 50.0 | 4.11e-01 | 76.9% | 42.1% |
| 5049143 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.69 | 58.0 | 4.58e-01 | 100.0% | 45.5% |
| 4948274 | 164.1.1.1 ↗ | alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › CM_2 | 0.68 | 47.0 | 4.22e-01 | 76.9% | 50.7% |
| 1693526 | 2008.1.1.70 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RE_BsaWI | 0.68 | 60.0 | 3.69e-01 | 96.2% | 21.0% |
| 5039471 | 164.1.1.1 ↗ | alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › CM_2 | 0.67 | 46.0 | 3.96e-01 | 75.0% | 42.2% |
| 4972595 | 102.1.1.0 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like | 0.67 | 58.0 | 4.59e-01 | 96.2% | 80.0% |
| 4502561 | 283.1.1.3 ↗ | a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › Creatinase/aminopeptidase › Creatinase/aminopeptidase › Pantoate_ligase | 0.67 | 60.0 | 4.71e-01 | 96.2% | 60.0% |
| 174462 | 2003.6.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Ribokinase-like › Ribokinase-like › PfkB | 0.67 | 59.0 | 3.62e-01 | 100.0% | 85.4% |
| 3284812 | 131.1.1.0 ↗ | alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like | 0.65 | 54.0 | 3.76e-01 | 96.2% | 90.0% |
| 3953159 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.65 | 57.0 | 4.22e-01 | 96.2% | 64.6% |
| 3704777 | 7064.1.1.1 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 | 0.64 | 57.0 | 3.94e-01 | 98.1% | 50.6% |
| 4992636 | 164.1.1.1 ↗ | alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › CM_2 | 0.64 | 46.0 | 3.72e-01 | 76.9% | 38.1% |
| 4926851 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.63 | 46.0 | 4.45e-01 | 78.8% | 90.0% |
| 4991198 | 2.1.1.359 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › HupF_HypC | 0.62 | 45.0 | 3.52e-01 | 75.0% | 33.9% |
| 3519655 | 101.1.10.33 ↗ | alpha arrays › HTH › HTH › Cyclin-like › Rrn7_cyclin_C | 0.62 | 51.0 | 3.76e-01 | 98.1% | 77.4% |
| 3688820 | 210.2.1.1 ↗ | a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C | 0.61 | 49.0 | 3.10e-01 | 98.1% | 68.8% |
| 4986992 | 2005.1.1.17 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › tRNA-synt_1f | 0.60 | 47.0 | 2.74e-01 | 96.2% | 9.0% |
| 5039558 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.60 | 52.0 | 3.89e-01 | 100.0% | 88.9% |
| 3241203 | 544.1.1.0 ↗ | alpha bundles › Functional domain of the splicing factor Prp18 › Functional domain of the splicing factor Prp18 › Functional domain of the splicing factor Prp18 | 0.59 | 48.0 | 3.72e-01 | 92.3% | 69.2% |
| 5076993 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.56 | 44.0 | 3.29e-01 | 88.5% | 75.2% |
| 3924569 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.55 | 43.0 | 3.32e-01 | 94.2% | 88.6% |
| 2796737 | 3009.1.1.0 ↗ | alpha arrays › Insertion subdomain in DsbA-like › Insertion subdomain in DsbA-like › Insertion subdomain in DsbA-like | 0.51 | 40.0 | 3.80e-01 | 86.5% | 71.0% |
D3
medium
residues 53-74_268-347
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03553.22 best | Na_H_antiporter | 43.8 | 2.80e-11 | 97.1% | 27.7% |
CATH (33)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2x2vA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.65 | 40.0 | 4.71e-01 | 96.1% | 92.6% |
| 2lyiA01 | 1.10.274.60 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain | 0.64 | 51.0 | 4.49e-01 | 84.3% | 81.8% |
| 3wvoC02 | 1.10.132.100 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.63 | 45.0 | 4.20e-01 | 74.5% | 96.9% |
| 2o1eB01 | 3.40.50.1980 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain | 0.63 | 48.0 | 4.28e-01 | 82.4% | 92.1% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.63 | 46.0 | 4.38e-01 | 77.5% | 91.0% |
| 2nrlA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.62 | 45.0 | 4.05e-01 | 76.5% | 97.2% |
| 4d2dA00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.62 | 54.0 | 3.52e-01 | 97.1% | 83.8% |
| 4jd9G00 | 1.10.238.20 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain | 0.62 | 47.0 | 4.48e-01 | 81.4% | 92.5% |
| 3ljbA00 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.62 | 45.0 | 3.60e-01 | 78.4% | 77.2% |
| 3rzeA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.61 | 44.0 | 3.29e-01 | 75.5% | 98.5% |
| 6ig5A01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.61 | 46.0 | 4.24e-01 | 81.4% | 69.6% |
| 1t6jA03 | 1.10.274.20 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Phenylalanine ammonia-lyase 1; domain 3 | 0.61 | 44.0 | 4.41e-01 | 75.5% | 85.4% |
| 1ichA00 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.61 | 41.0 | 4.34e-01 | 79.4% | 80.5% |
| 6o7uc01 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.60 | 38.0 | 3.10e-01 | 100.0% | 33.2% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.60 | 44.0 | 4.29e-01 | 76.5% | 99.1% |
| 1wxpA01 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.60 | 40.0 | 4.37e-01 | 79.4% | 84.5% |
| 6k41R00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.59 | 43.0 | 3.27e-01 | 75.5% | 97.9% |
| 3emlA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.58 | 43.0 | 3.16e-01 | 78.4% | 96.5% |
| 1wp7A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.58 | 34.0 | 3.98e-01 | 93.1% | 89.1% |
| 2b5uA02 | 1.10.287.620 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins | 0.58 | 37.0 | 3.21e-01 | 100.0% | 41.0% |
| 1eq1A00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.58 | 47.0 | 4.05e-01 | 89.2% | 80.1% |
| 3ezuA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.57 | 41.0 | 3.48e-01 | 77.5% | 76.4% |
| 3ihuA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.56 | 46.0 | 4.18e-01 | 90.2% | 96.4% |
| 4hd1A00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.55 | 42.0 | 3.19e-01 | 82.4% | 65.4% |
| 1t72A02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.55 | 36.0 | 3.64e-01 | 100.0% | 67.3% |
| 4qicC01 | 1.20.140.160 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › PhyR, sigma-like (SL) domain | 0.55 | 40.0 | 3.78e-01 | 76.5% | 68.8% |
| 1wpaA01 | 6.10.140.340 | Special › Helix non-globular › Helix Hairpins › | 0.54 | 41.0 | 4.16e-01 | 100.0% | 80.8% |
| 2c41C01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.54 | 40.0 | 3.54e-01 | 77.5% | 69.1% |
| 3h4cA01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.53 | 37.0 | 3.83e-01 | 72.5% | 78.1% |
| 2ddhA04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.52 | 36.0 | 3.35e-01 | 70.6% | 79.5% |
| 4iu9B02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.52 | 41.0 | 3.35e-01 | 87.3% | 94.6% |
| 2ntxA01 | 1.20.58.2010 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › PRONE domain, subdomain 1 | 0.50 | 39.0 | 3.13e-01 | 84.3% | 67.1% |
| 2di3B02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.50 | 36.0 | 3.24e-01 | 76.5% | 53.5% |
ECOD (44)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3963976 | 3355.1.1.8 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_H_antiporter | 0.97 | 94.0 | 5.83e-01 | 100.0% | 58.9% |
| 3971875 | 3355.1.1.0 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter | 0.96 | 93.0 | 5.81e-01 | 100.0% | 59.5% |
| 4329689 | 140.1.1.14 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e | 0.65 | 48.0 | 4.15e-01 | 77.5% | 85.2% |
| 4168957 | 1197.1.1.1 ↗ | alpha bundles › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › G3P_acyltransf | 0.64 | 48.0 | 3.82e-01 | 77.5% | 73.3% |
| 3280449 | 5065.1.1.3 ↗ | alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › BPD_transp_2 | 0.64 | 55.0 | 3.91e-01 | 96.1% | 80.0% |
| 3285171 | 604.39.1.0 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters | 0.63 | 43.0 | 3.53e-01 | 70.6% | 42.5% |
| 4046776 | 1197.1.1.1 ↗ | alpha bundles › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › G3P_acyltransf | 0.63 | 48.0 | 3.85e-01 | 80.4% | 73.3% |
| 3219915 | 2485.1.1.49 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › Thioredoxin_12 | 0.62 | 45.0 | 3.74e-01 | 76.5% | 98.3% |
| 4637554 | 140.1.1.7 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_2 | 0.61 | 47.0 | 3.84e-01 | 81.4% | 83.2% |
| 4003656 | 5048.1.1.1 ↗ | alpha complex topology › Aquaporin-like › Aquaporin-like › Aquaporin-like › MIP | 0.61 | 44.0 | 3.66e-01 | 75.5% | 96.7% |
| 3601315 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.60 | 39.0 | 3.09e-01 | 100.0% | 32.7% |
| 5039082 | 3646.1.1.1 ↗ | alpha complex topology › T-component of energy-coupling factor (ECF) transporters › T-component of energy-coupling factor (ECF) transporters › T-component of energy-coupling factor (ECF) transporters › CbiQ | 0.60 | 48.0 | 3.59e-01 | 85.3% | 82.4% |
| 4150655 | 3758.2.1.1 ↗ | alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB | 0.59 | 43.0 | 3.39e-01 | 78.4% | 87.6% |
| 3360734 | 101.1.10.21 ↗ | alpha arrays › HTH › HTH › Cyclin-like › Cyclin_N,Cyclin_C | 0.58 | 42.0 | 3.15e-01 | 74.5% | 33.2% |
| 4033275 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.58 | 37.0 | 3.74e-01 | 100.0% | 64.0% |
| 3999676 | 188.1.1.0 ↗ | alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain | 0.58 | 40.0 | 3.41e-01 | 72.5% | 96.1% |
| 3170063 | 180.1.1.1 ↗ | alpha bundles › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › PAP2 | 0.58 | 44.0 | 3.67e-01 | 82.4% | 65.3% |
| 3866994 | 601.19.1.36 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › DUF4455 | 0.57 | 42.0 | 3.61e-01 | 78.4% | 91.4% |
| 3948470 | 5065.1.1.1 ↗ | alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › ABC-3 | 0.57 | 50.0 | 3.73e-01 | 100.0% | 86.8% |
| 3285842 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.57 | 48.0 | 4.00e-01 | 95.1% | 93.2% |
| 4011226 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.57 | 46.0 | 3.79e-01 | 91.2% | 93.5% |
| 4045493 | 5065.1.1.1 ↗ | alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › ABC-3 | 0.56 | 50.0 | 3.69e-01 | 100.0% | 85.4% |
| 3599346 | 3236.1.1.0 ↗ | alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) | 0.56 | 41.0 | 2.74e-01 | 85.3% | 18.4% |
| 3589723 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.56 | 40.0 | 3.74e-01 | 100.0% | 60.8% |
| 4110399 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.56 | 48.0 | 3.66e-01 | 96.1% | 76.4% |
| 3713124 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.56 | 45.0 | 3.85e-01 | 91.2% | 97.8% |
| 4960932 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.55 | 43.0 | 3.59e-01 | 85.3% | 94.2% |
| 3264853 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.55 | 40.0 | 3.74e-01 | 78.4% | 97.8% |
| 3504306 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.55 | 39.0 | 3.94e-01 | 75.5% | 98.1% |
| 3709809 | 4156.1.1.4 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_C | 0.54 | 45.0 | 4.08e-01 | 92.2% | 69.3% |
| 4929352 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.54 | 44.0 | 3.56e-01 | 90.2% | 65.9% |
| 4360664 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.54 | 46.0 | 3.62e-01 | 95.1% | 80.4% |
| 3515796 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.54 | 39.0 | 3.32e-01 | 100.0% | 45.9% |
| 4679675 | 628.1.1.1 ↗ | alpha bundles › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › FCD | 0.54 | 46.0 | 4.02e-01 | 97.1% | 92.5% |
| 4124062 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.53 | 41.0 | 3.28e-01 | 83.3% | 82.8% |
| 3722161 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.52 | 43.0 | 3.35e-01 | 91.2% | 70.9% |
| 3286850 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.52 | 45.0 | 3.66e-01 | 99.0% | 90.6% |
| 4436109 | 140.1.1.14 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e | 0.52 | 40.0 | 3.41e-01 | 81.4% | 93.3% |
| 312606 | 5065.1.1.2 ↗ | alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › FecCD | 0.51 | 45.0 | 3.30e-01 | 100.0% | 77.7% |
| 3515403 | 5050.1.1.6 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › OATP | 0.51 | 43.0 | 3.35e-01 | 96.1% | 71.2% |
| None | — | 0.51 | 43.0 | 3.01e-01 | 100.0% | 26.2% | |
| 3829426 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.51 | 44.0 | 3.48e-01 | 98.0% | 90.2% |
| 5012015 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.51 | 39.0 | 3.36e-01 | 84.3% | 93.1% |
| 4964442 | 2003.1.1.24 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Shikimate_DH | 0.50 | 44.0 | 3.32e-01 | 99.0% | 62.7% |
D4
medium
residues 348-474
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03553.22 best | Na_H_antiporter | 144.3 | 7.00e-42 | 95.3% | 40.6% |
CATH (24)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2b8iA00 | 1.20.1280.100 | Mainly Alpha › Up-down Bundle › Monooxygenase › Pas factor, saposin domain | 0.73 | 45.0 | 5.48e-01 | 85.8% | 100.0% |
| 2kjgA00 | 1.20.120.970 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.71 | 42.0 | 4.66e-01 | 86.6% | 73.7% |
| 2zy9A03 | 1.10.357.20 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › SLC41 divalent cation transporters, integral membrane domain | 0.64 | 51.0 | 4.66e-01 | 87.4% | 79.9% |
| 4zvaA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.63 | 38.0 | 3.64e-01 | 74.0% | 51.0% |
| 4uiqB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.61 | 38.0 | 3.58e-01 | 73.2% | 51.0% |
| 3p5nA00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.60 | 50.0 | 4.59e-01 | 98.4% | 68.5% |
| 1w98B02 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.60 | 33.0 | 3.49e-01 | 74.8% | 59.6% |
| 2zcxA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.60 | 53.0 | 4.54e-01 | 98.4% | 68.3% |
| 6kd7A00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.58 | 52.0 | 3.85e-01 | 98.4% | 89.6% |
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.58 | 43.0 | 3.78e-01 | 77.2% | 85.6% |
| 5dqqA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.57 | 36.0 | 3.64e-01 | 74.8% | 61.4% |
| 5iduC03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.56 | 38.0 | 3.54e-01 | 82.7% | 54.7% |
| 1e6vB02 | 1.20.840.10 | Mainly Alpha › Up-down Bundle › Methyl-coenzyme M Reductase; Chain B, domain 2 › Methyl-coenzyme M reductase, alpha/beta subunit, C-terminal | 0.56 | 46.0 | 3.58e-01 | 89.8% | 57.4% |
| 4mbsA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.55 | 46.0 | 3.45e-01 | 92.1% | 84.1% |
| 4rocA01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.54 | 30.0 | 3.30e-01 | 70.1% | 65.0% |
| 5zw7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.54 | 36.0 | 3.49e-01 | 75.6% | 57.9% |
| 6o7uc01 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.53 | 39.0 | 3.49e-01 | 78.0% | 71.6% |
| 3we9A00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.53 | 48.0 | 3.86e-01 | 100.0% | 77.3% |
| 1hw1A02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.53 | 46.0 | 4.40e-01 | 96.1% | 97.4% |
| 2nwlC00 | 1.10.3860.10 | Mainly Alpha › Orthogonal Bundle › Proton glutamate symport protein › Sodium:dicarboxylate symporter | 0.52 | 45.0 | 3.29e-01 | 100.0% | 54.1% |
| 2j9wB00 | 1.20.120.1130 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vps28 C-terminal domain | 0.51 | 37.0 | 4.11e-01 | 94.5% | 97.0% |
| 2y44A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.51 | 37.0 | 3.33e-01 | 76.4% | 85.3% |
| 2zcaA00 | 1.10.520.40 | Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › CRISPR-associated protein Cse2 | 0.50 | 41.0 | 3.86e-01 | 87.4% | 88.4% |
| 2wbiB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.50 | 35.0 | 3.28e-01 | 72.4% | 57.0% |
ECOD (69)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3963976 | 3355.1.1.8 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_H_antiporter | 0.99 | 95.0 | 6.13e-01 | 98.4% | 27.4% |
| 3971875 | 3355.1.1.0 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter | 0.94 | 88.0 | 5.77e-01 | 97.6% | 28.0% |
| 3839299 | 3355.1.1.8 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_H_antiporter | 0.93 | 87.0 | 5.74e-01 | 97.6% | 29.0% |
| 3973556 | 3355.1.1.0 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter | 0.87 | 78.0 | 5.25e-01 | 100.0% | 28.9% |
| 5079301 | 3355.1.1.4 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › DctM | 0.87 | 77.0 | 5.30e-01 | 100.0% | 30.4% |
| 4955460 | 3355.1.1.4 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › DctM | 0.86 | 79.0 | 5.41e-01 | 100.0% | 31.5% |
| 3386573 | 3355.1.1.12 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › DcuA_DcuB | 0.84 | 79.0 | 5.23e-01 | 100.0% | 28.3% |
| 3290255 | 3355.1.1.4 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › DctM | 0.84 | 80.0 | 5.38e-01 | 100.0% | 32.0% |
| 3941743 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.83 | 75.0 | 5.13e-01 | 100.0% | 29.8% |
| 4965099 | 3355.1.1.8 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_H_antiporter | 0.83 | 76.0 | 4.99e-01 | 100.0% | 25.5% |
| 5050449 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.83 | 76.0 | 5.15e-01 | 99.2% | 29.8% |
| 3964662 | 3355.1.1.11 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › GntP_permease | 0.82 | 72.0 | 4.82e-01 | 100.0% | 26.4% |
| 5050010 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.82 | 75.0 | 4.98e-01 | 100.0% | 27.6% |
| 4335348 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.82 | 74.0 | 5.07e-01 | 100.0% | 30.9% |
| 3942409 | 3355.1.1.3 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › ABG_transport | 0.81 | 75.0 | 5.00e-01 | 100.0% | 28.5% |
| 3976891 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.81 | 74.0 | 5.06e-01 | 100.0% | 29.9% |
| 5063799 | 3355.1.1.8 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_H_antiporter | 0.81 | 75.0 | 4.95e-01 | 100.0% | 26.2% |
| None | — | 0.81 | 75.0 | 4.96e-01 | 100.0% | 26.7% | |
| 4998532 | 3355.1.1.1 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_sulph_symp | 0.81 | 76.0 | 5.05e-01 | 100.0% | 94.5% |
| 3943055 | 3355.1.1.16 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › DcuC | 0.81 | 75.0 | 4.99e-01 | 100.0% | 28.0% |
| 4047576 | 3355.1.1.21 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_sulph_symp, CitMHS | 0.81 | 73.0 | 4.95e-01 | 100.0% | 28.5% |
| 4994403 | 109.3.1.480 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Na_H_antiporter | 0.80 | 71.0 | 6.77e-01 | 99.2% | 83.4% |
| 5047110 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.80 | 70.0 | 4.73e-01 | 100.0% | 27.7% |
| 5064843 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.80 | 73.0 | 5.02e-01 | 100.0% | 30.7% |
| 4999175 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.79 | 73.0 | 5.00e-01 | 100.0% | 30.5% |
| 4033812 | 3355.1.1.8 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_H_antiporter | 0.79 | 74.0 | 4.96e-01 | 100.0% | 78.0% |
| 4948122 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.79 | 69.0 | 4.75e-01 | 98.4% | 28.6% |
| 4238771 | 3355.1.1.8 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_H_antiporter | 0.78 | 73.0 | 4.87e-01 | 100.0% | 74.7% |
| 5020409 | 3355.1.1.11 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › GntP_permease | 0.78 | 68.0 | 4.55e-01 | 99.2% | 26.3% |
| 4030857 | 3355.1.1.16 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › DcuC | 0.78 | 71.0 | 4.80e-01 | 100.0% | 28.4% |
| 4140252 | 3355.1.1.8 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_H_antiporter | 0.78 | 72.0 | 4.91e-01 | 100.0% | 80.7% |
| 3591004 | 3355.1.1.8 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_H_antiporter | 0.78 | 73.0 | 4.85e-01 | 100.0% | 75.3% |
| None | — | 0.78 | 71.0 | 4.92e-01 | 100.0% | 31.5% | |
| 3164464 | 3355.1.1.8 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_H_antiporter | 0.78 | 73.0 | 4.84e-01 | 100.0% | 77.0% |
| 4944772 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.78 | 72.0 | 4.88e-01 | 100.0% | 31.0% |
| 3163671 | 3355.1.1.11 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › GntP_permease | 0.77 | 70.0 | 4.82e-01 | 98.4% | 99.8% |
| 5007958 | 3355.1.1.4 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › DctM | 0.77 | 66.0 | 4.39e-01 | 92.9% | 24.9% |
| 5044722 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.77 | 72.0 | 4.85e-01 | 100.0% | 99.1% |
| 5009976 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.77 | 68.0 | 4.76e-01 | 99.2% | 31.3% |
| 3965474 | 3355.1.1.8 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_H_antiporter | 0.77 | 71.0 | 4.80e-01 | 100.0% | 77.0% |
| 3415460 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.76 | 70.0 | 4.56e-01 | 98.4% | 24.8% |
| 4982640 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.76 | 67.0 | 4.56e-01 | 98.4% | 28.3% |
| 4230575 | 3355.1.1.16 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › DcuC | 0.76 | 70.0 | 4.69e-01 | 100.0% | 88.8% |
| 5074711 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.76 | 69.0 | 4.77e-01 | 100.0% | 30.2% |
| 5020524 | 3355.1.1.42 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › DUF1646 | 0.75 | 65.0 | 4.66e-01 | 100.0% | 32.7% |
| 4622106 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.74 | 68.0 | 4.61e-01 | 100.0% | 99.5% |
| 4945009 | 5079.1.1.1 ↗ | alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE | 0.67 | 54.0 | 4.86e-01 | 87.4% | 83.3% |
| 4955719 | 5079.1.1.1 ↗ | alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE | 0.66 | 54.0 | 4.69e-01 | 87.4% | 75.9% |
| 4979261 | 5079.1.1.1 ↗ | alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE | 0.66 | 53.0 | 4.73e-01 | 87.4% | 85.8% |
| 4954003 | 5079.1.1.1 ↗ | alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE | 0.65 | 53.0 | 4.72e-01 | 88.2% | 78.9% |
| 5018946 | 5079.1.1.1 ↗ | alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE | 0.64 | 52.0 | 4.61e-01 | 87.4% | 81.4% |
| 4871311 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.64 | 45.0 | 4.56e-01 | 73.2% | 73.4% |
| 4965550 | 5079.1.1.1 ↗ | alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE | 0.64 | 51.0 | 4.58e-01 | 87.4% | 81.6% |
| 4965551 | 5079.1.1.1 ↗ | alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE | 0.63 | 51.0 | 4.58e-01 | 88.2% | 81.7% |
| 3889250 | 5001.1.1.31 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › GPR180-TMEM145_TM | 0.63 | 52.0 | 3.96e-01 | 89.0% | 72.9% |
| 4942128 | 604.39.1.0 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters | 0.61 | 49.0 | 4.64e-01 | 99.2% | 71.6% |
| 3615254 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 50.0 | 3.65e-01 | 87.4% | 87.4% |
| 4264622 | 604.39.1.5 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › ECF_trnsprt | 0.60 | 49.0 | 4.38e-01 | 98.4% | 61.2% |
| 4941726 | 5079.1.1.1 ↗ | alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE | 0.60 | 48.0 | 4.05e-01 | 87.4% | 66.4% |
| 3927814 | 5001.1.1.35 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srsx | 0.59 | 43.0 | 3.35e-01 | 76.4% | 42.8% |
| 3963990 | 1075.3.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 | 0.57 | 46.0 | 3.91e-01 | 89.0% | 61.8% |
| 3213286 | 5001.1.1.63 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srab | 0.56 | 45.0 | 3.53e-01 | 86.6% | 85.6% |
| 4579440 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.56 | 48.0 | 4.09e-01 | 96.9% | 96.3% |
| 3810020 | 5076.1.1.1 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr | 0.55 | 43.0 | 3.26e-01 | 85.8% | 69.9% |
| 5025769 | 1076.1.1.0 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related | 0.55 | 42.0 | 3.64e-01 | 82.7% | 84.4% |
| 4580475 | 3684.1.1.28 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PF26154 | 0.53 | 44.0 | 4.49e-01 | 96.9% | 92.8% |
| 3516718 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.52 | 43.0 | 3.73e-01 | 89.0% | 61.0% |
| 5037027 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.52 | 39.0 | 3.77e-01 | 81.1% | 92.0% |
| 5081839 | 109.10.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin | 0.51 | 37.0 | 3.21e-01 | 75.6% | 49.8% |