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CAKLQF020000005.1__CAH1078001.1__SAMEA5780031_01189__00037

Bact-Vir

CAKLQF020000005.1__CAH1078001.1__SAMEA5780031_01189__00037

Identity

Kingdom:
phage

Quality

85.7 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 171-347
PDB
Domain cluster: representative
CATH (51)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3kmiA00 1.20.120.940 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Putative aromatic acid exporter, C-terminal domain 0.79 73.0 7.45e-01 98.3% 100.0%
1xwmA00 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.77 72.0 6.77e-01 100.0% 94.8%
4k0dA00 1.20.120.1730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.77 49.0 5.37e-01 100.0% 77.6%
4iggB02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.75 49.0 5.80e-01 100.0% 95.0%
1zvzA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.75 50.0 5.90e-01 100.0% 96.8%
1dowA00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.74 49.0 4.63e-01 100.0% 56.6%
2kbbA00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.74 49.0 5.02e-01 100.0% 67.8%
3dyjA01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.74 52.0 5.40e-01 100.0% 75.9%
1st6A04 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.73 47.0 5.69e-01 100.0% 98.3%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.72 51.0 5.91e-01 100.0% 99.2%
2l10A00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.72 48.0 5.07e-01 100.0% 74.7%
4hkrA00 1.20.140.140 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Calcium release-activated calcium channel protein Orai 0.71 41.0 4.31e-01 85.3% 60.6%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.71 48.0 5.44e-01 100.0% 91.5%
2xq9A02 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.71 48.0 5.68e-01 100.0% 99.2%
1b68A00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.71 52.0 5.82e-01 100.0% 96.4%
2hfiA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.70 45.0 5.31e-01 99.4% 91.9%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.70 46.0 5.45e-01 100.0% 98.3%
2d4uB00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.70 47.0 5.03e-01 100.0% 78.1%
5h5mA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.68 49.0 5.58e-01 98.9% 99.2%
1m56C02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.67 51.0 4.93e-01 100.0% 70.4%
1yjgA00 1.20.120.240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 0.66 51.0 5.39e-01 100.0% 90.4%
1xioA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.65 46.0 4.30e-01 100.0% 58.1%
6nsjA00 1.25.40.600 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › AmiS/UreI transporter 0.65 45.0 4.45e-01 100.0% 67.6%
1dlcA01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.65 47.0 4.26e-01 98.9% 56.8%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.65 38.0 4.83e-01 98.9% 96.3%
5d91A02 1.20.120.1760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain 0.64 40.0 3.91e-01 94.4% 55.6%
6t0bc02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.63 47.0 4.57e-01 100.0% 70.7%
3i9yA00 1.20.58.920 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 57.0 5.17e-01 100.0% 81.7%
5azpB01 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.60 44.0 3.40e-01 73.4% 84.0%
3caxA01 1.20.120.520 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like 0.60 44.0 4.14e-01 100.0% 61.3%
2cmrA00 1.20.58.1860 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 47.0 4.58e-01 81.9% 96.9%
1q16C01 1.20.950.20 Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C 0.59 52.0 4.93e-01 100.0% 78.5%
4e40A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.59 50.0 4.44e-01 89.3% 79.6%
4mycA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.57 52.0 4.24e-01 98.9% 93.9%
4mt4A00 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.57 41.0 3.04e-01 74.6% 83.9%
2d1lA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.57 47.0 4.17e-01 87.0% 79.1%
1c17M00 1.20.120.220 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ATP synthase, F0 complex, subunit A 0.56 41.0 4.50e-01 100.0% 93.7%
2y44A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.56 47.0 4.71e-01 89.3% 92.4%
1wdzA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.54 45.0 4.10e-01 87.0% 85.7%
3pltA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.54 45.0 4.20e-01 87.0% 77.6%
4f4cA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.53 49.0 3.24e-01 100.0% 44.3%
3ok8A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.53 44.0 4.11e-01 87.6% 85.4%
1q90B00 1.20.810.10 Mainly Alpha › Up-down Bundle › Cytochrome Bc1 Complex; Chain C › Cytochrome Bc1 Complex; Chain C 0.53 49.0 4.62e-01 100.0% 83.0%
1x04A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.53 44.0 4.21e-01 87.0% 86.0%
6h2dS01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.53 44.0 4.08e-01 88.7% 88.3%
6v9zA02 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.52 48.0 3.92e-01 99.4% 93.2%
1i4dA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.52 43.0 4.29e-01 88.1% 89.9%
2v0oB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.52 43.0 3.70e-01 87.0% 77.1%
3qhbA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.52 45.0 4.52e-01 99.4% 92.2%
6xj1A01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.51 42.0 3.74e-01 87.0% 86.9%
4nswB01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.51 42.0 3.69e-01 87.0% 71.1%
ECOD (70)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3975942 601.4.1.6 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TorS_sensor_domain 0.86 51.0 5.94e-01 100.0% 80.8%
3943935 601.1.1.89 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › FUSC 0.84 73.0 7.60e-01 100.0% 97.6%
3982841 604.5.1.33 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › FUSC 0.83 72.0 7.62e-01 99.4% 100.0%
4174741 601.1.2.77 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › FUSC 0.83 73.0 7.36e-01 100.0% 92.0%
3966859 604.5.1.33 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › FUSC 0.82 78.0 7.50e-01 100.0% 95.5%
4949599 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.82 58.0 6.42e-01 100.0% 87.6%
3973008 601.14.1.0 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin 0.81 76.0 7.43e-01 98.9% 99.5%
3276293 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.81 77.0 6.94e-01 100.0% 93.9%
3740474 604.5.1.16 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › ArAE_2_N 0.81 76.0 6.76e-01 100.0% 97.6%
3967618 604.5.1.33 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › FUSC 0.79 75.0 7.36e-01 100.0% 98.4%
4184759 601.1.1.89 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › FUSC 0.79 67.0 5.35e-01 100.0% 48.1%
4993153 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.79 74.0 7.06e-01 100.0% 97.6%
5032558 604.5.1.1 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div 0.79 74.0 6.99e-01 100.0% 97.6%
4039850 601.1.1.89 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › FUSC 0.79 67.0 6.73e-01 100.0% 88.0%
3650756 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.79 75.0 6.90e-01 100.0% 93.6%
4009779 601.4.1.1 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TarH 0.79 54.0 6.19e-01 100.0% 91.1%
5044306 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.79 73.0 7.03e-01 98.3% 100.0%
3943375 192.29.1.120 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › FUSC 0.79 66.0 6.79e-01 100.0% 90.6%
4681963 633.10.1.16 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › FUSC 0.79 66.0 6.79e-01 100.0% 90.6%
4078334 604.5.1.33 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › FUSC 0.79 66.0 6.78e-01 100.0% 90.6%
5026989 604.5.1.1 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div 0.78 74.0 6.77e-01 100.0% 99.1%
4260974 601.4.1.53 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › FUSC 0.78 66.0 6.77e-01 100.0% 90.6%
3272683 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.78 74.0 6.49e-01 100.0% 97.2%
3266289 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.78 74.0 6.93e-01 99.4% 99.0%
4643195 601.4.1.53 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › FUSC 0.78 65.0 6.69e-01 100.0% 90.0%
4999600 604.5.1.1 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div 0.78 73.0 6.92e-01 100.0% 99.5%
3991480 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.78 55.0 6.04e-01 100.0% 87.6%
4976786 604.5.1.1 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div 0.77 73.0 6.84e-01 100.0% 97.6%
4993201 604.5.1.1 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div 0.77 73.0 6.72e-01 100.0% 94.1%
4934608 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.77 56.0 6.27e-01 100.0% 94.3%
3969777 601.1.1.89 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › FUSC 0.76 65.0 6.80e-01 97.7% 100.0%
4927274 604.5.1.1 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div 0.76 71.0 6.65e-01 100.0% 97.6%
4681797 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.76 71.0 6.80e-01 100.0% 96.0%
4479929 601.1.1.89 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › FUSC 0.75 71.0 6.87e-01 100.0% 94.4%
4950112 604.5.1.1 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div 0.75 71.0 6.72e-01 100.0% 97.1%
3964451 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.75 71.0 6.81e-01 100.0% 89.0%
4946592 604.5.1.1 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div 0.75 70.0 6.61e-01 100.0% 98.1%
4992506 604.5.1.1 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div 0.75 69.0 6.63e-01 98.9% 99.5%
5047777 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.74 69.0 6.62e-01 98.3% 99.5%
5023678 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.74 69.0 6.79e-01 99.4% 100.0%
3965437 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.74 69.0 6.87e-01 100.0% 97.3%
4934327 604.5.1.1 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div 0.73 68.0 6.34e-01 100.0% 96.3%
5026318 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.73 68.0 6.77e-01 100.0% 98.9%
4928241 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.73 67.0 6.74e-01 97.2% 100.0%
4991795 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.73 67.0 6.83e-01 100.0% 100.0%
5039563 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.72 67.0 6.36e-01 100.0% 96.1%
4952094 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.72 52.0 5.47e-01 100.0% 81.2%
4360597 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.72 64.0 6.56e-01 98.9% 98.8%
4032906 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.71 54.0 6.00e-01 100.0% 100.0%
3453285 3562.1.1.11 alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › PGG 0.71 39.0 4.44e-01 85.3% 70.4%
3243897 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.70 49.0 5.50e-01 100.0% 90.7%
3233670 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.68 48.0 5.30e-01 100.0% 88.3%
3949780 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.68 38.0 3.79e-01 90.4% 51.9%
3838201 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.65 40.0 4.04e-01 92.7% 61.1%
4928414 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.65 39.0 3.90e-01 90.4% 56.2%
4972007 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.64 44.0 4.88e-01 100.0% 87.1%
5051714 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.61 52.0 5.08e-01 87.6% 98.4%
3811131 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.60 42.0 3.50e-01 81.4% 42.6%
3721596 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.59 41.0 4.75e-01 100.0% 96.2%
1824764 1189.1.1.4 alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › HpHbR 0.58 50.0 4.39e-01 89.3% 78.3%
3556381 3755.3.1.530 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PPP1R21_helical 0.57 53.0 4.57e-01 100.0% 66.2%
4043617 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.57 52.0 4.37e-01 99.4% 60.0%
4524452 150.1.1.186 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › PPP1R21_helical 0.57 53.0 4.66e-01 100.0% 70.2%
3620083 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.56 49.0 5.06e-01 99.4% 97.1%
3202451 3567.1.1.51 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › Fung_rhodopsin 0.54 44.0 4.33e-01 100.0% 79.5%
3299452 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.54 38.0 4.03e-01 78.5% 83.3%
3273901 4177.1.1.8 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3 0.54 45.0 3.90e-01 87.0% 71.5%
3402136 4177.1.1.8 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3 0.51 42.0 3.76e-01 87.0% 75.1%
3232199 4177.1.1.10 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › GMIP-like_FCH 0.51 42.0 3.61e-01 87.0% 77.4%
4191633 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.50 40.0 3.71e-01 84.7% 79.1%
D2 medium residues 15-170
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF04632.19 best FUSC 201.4 4.10e-59 100.0% 23.1%
PF13515.13 FUSC_2 50.9 2.30e-13 87.8% 99.2%
CATH (24)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.77 33.0 3.93e-01 74.4% 58.3%
8bb6A01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.70 51.0 3.64e-01 75.6% 90.6%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.67 38.0 4.52e-01 80.1% 81.3%
5x9vA01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.66 59.0 5.03e-01 95.5% 98.4%
3p9dG01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.65 59.0 4.99e-01 97.4% 94.9%
2xq2A01 1.20.1730.10 Mainly Alpha › Up-down Bundle › Sodium/glucose cotransporter › Sodium/glucose cotransporter 0.64 52.0 3.58e-01 86.5% 50.7%
6ks6q01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.64 58.0 4.77e-01 97.4% 90.5%
3kttB01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.64 57.0 4.79e-01 96.2% 95.7%
4cqiA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 35.0 4.14e-01 75.0% 77.6%
4f4cA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.59 45.0 2.88e-01 79.5% 69.4%
5aexJ00 1.10.3430.10 Mainly Alpha › Orthogonal Bundle › Ammonium transporter fold › Ammonium transporter AmtB like domains 0.57 51.0 3.77e-01 100.0% 60.7%
1sziA02 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.57 40.0 4.22e-01 71.2% 92.0%
5nx5B00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.56 40.0 3.26e-01 72.4% 95.9%
3zdqA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.55 39.0 3.00e-01 70.5% 85.6%
2odvA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 32.0 3.69e-01 76.3% 79.5%
7dfeA01 1.10.274.60 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain 0.54 32.0 3.52e-01 97.4% 70.1%
4gkfA00 1.10.520.30 Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › AF1862-like domain 0.54 42.0 4.34e-01 81.4% 97.3%
7uzqK01 1.10.3430.10 Mainly Alpha › Orthogonal Bundle › Ammonium transporter fold › Ammonium transporter AmtB like domains 0.54 48.0 3.73e-01 100.0% 65.8%
1sgmA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.53 33.0 3.14e-01 82.7% 50.5%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.52 32.0 2.76e-01 97.4% 39.0%
6v9zA02 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.52 37.0 2.89e-01 71.8% 87.4%
5dz2A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.52 39.0 3.15e-01 78.8% 68.3%
2zopA00 1.10.520.30 Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › AF1862-like domain 0.51 36.0 4.07e-01 83.3% 100.0%
1foeA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.51 36.0 3.34e-01 73.1% 88.5%
ECOD (43)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4377602 109.4.1.3456 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › FUSC 0.95 90.0 6.77e-01 96.8% 47.2%
3805429 3562.1.1.33 alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › ALMT 0.90 84.0 8.40e-01 97.4% 99.4%
3314927 7064.1.1.5 alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › ALMT 0.90 84.0 8.21e-01 96.8% 98.8%
3834034 5067.1.1.13 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ALMT 0.90 86.0 8.42e-01 99.4% 98.2%
3835030 604.5.1.7 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › ALMT 0.89 84.0 8.26e-01 98.1% 100.0%
3264196 5067.1.1.13 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ALMT 0.89 86.0 8.40e-01 100.0% 99.4%
3663646 7064.1.1.5 alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › ALMT 0.89 69.0 7.67e-01 78.8% 100.0%
3330538 5067.1.1.13 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ALMT 0.89 83.0 7.69e-01 97.4% 84.7%
3297362 5067.1.1.13 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ALMT 0.89 84.0 8.21e-01 98.1% 98.2%
3175660 5067.1.1.14 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › FUSC_2 0.88 83.0 6.20e-01 97.4% 46.2%
3696827 604.5.1.27 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › FUSC_2 0.88 85.0 5.18e-01 100.0% 21.6%
3277315 1075.1.1.59 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ALMT 0.88 84.0 6.39e-01 99.4% 50.0%
3367916 5067.1.1.13 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ALMT 0.88 79.0 7.97e-01 93.6% 98.7%
3248399 3921.1.1.7 alpha complex topology › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › ALMT 0.87 81.0 6.20e-01 96.8% 48.9%
3267773 3921.1.1.6 alpha complex topology › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › FUSC_2 0.84 77.0 5.89e-01 96.8% 48.3%
3757364 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.70 52.0 3.80e-01 77.6% 85.8%
3192289 7064.1.1.1 alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 0.68 49.0 4.77e-01 75.0% 72.6%
5071140 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.67 31.0 3.20e-01 73.7% 44.7%
3587934 1075.1.2.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain 0.66 49.0 4.28e-01 75.6% 75.4%
3285186 5067.1.1.2 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › SecD_SecF 0.66 49.0 4.37e-01 76.3% 85.0%
4306505 5067.1.1.2 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › SecD_SecF 0.65 48.0 4.31e-01 75.0% 88.6%
3719714 1188.1.1.0 alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter 0.65 47.0 3.99e-01 73.7% 77.1%
4620700 5050.1.1.81 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › TerC 0.64 56.0 4.75e-01 93.6% 68.4%
3653751 5058.1.1.11 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › TerC 0.62 53.0 4.64e-01 91.0% 71.7%
3946069 1079.1.1.1 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › DsbD 0.61 49.0 4.40e-01 85.3% 81.9%
4397663 5067.1.1.0 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain 0.60 45.0 4.20e-01 77.6% 84.0%
4958586 1079.1.1.5 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › DsbD_2 0.60 48.0 4.27e-01 85.9% 81.3%
3282116 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.59 46.0 3.32e-01 81.4% 59.8%
5029675 3236.1.1.1 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.59 44.0 3.31e-01 77.6% 42.5%
4013168 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.58 44.0 3.23e-01 78.8% 76.6%
5048105 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.58 48.0 3.87e-01 87.8% 90.0%
3288182 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.57 44.0 3.68e-01 82.7% 88.4%
3189424 5050.1.1.12 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › TRI12 0.56 41.0 3.54e-01 74.4% 81.6%
4972429 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.54 44.0 3.72e-01 86.5% 60.8%
5052013 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.54 42.0 3.43e-01 82.1% 91.8%
3693274 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.54 39.0 3.13e-01 74.4% 76.5%
3959831 5067.1.1.0 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain 0.53 46.0 4.70e-01 98.1% 96.0%
4938615 5067.1.1.4 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › MMPL 0.53 45.0 4.33e-01 94.9% 78.9%
4997475 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.53 41.0 3.44e-01 82.7% 91.4%
4344623 3758.2.1.1 alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB 0.52 38.0 3.46e-01 74.4% 71.0%
5030859 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.51 37.0 4.15e-01 96.2% 99.2%
5048217 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.50 44.0 3.71e-01 94.2% 87.8%
4507521 304.107.1.3 a+b two layers › Alpha-beta plaits › Aminomethyltransferase folate-binding domain › Aminomethyltransferase folate-binding domain › TrmE_N 0.50 37.0 3.16e-01 77.6% 93.5%
D3 medium residues 361-525
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04632.19 best FUSC 128.6 4.30e-37 99.4% 24.3%
CATH (16)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6ks6Z01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.65 58.0 4.85e-01 93.9% 93.3%
3p9dE01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.65 57.0 4.84e-01 93.9% 94.7%
6ks6q01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.64 56.0 4.74e-01 93.9% 90.1%
5x9vA01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.63 56.0 4.88e-01 94.5% 99.2%
3tl4X02 1.10.10.2420 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.62 28.0 4.02e-01 78.2% 94.4%
5nl6A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 33.0 4.13e-01 75.8% 81.5%
1e1dA02 1.20.1270.20 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.60 26.0 3.52e-01 93.3% 77.4%
6wbvA01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.60 43.0 3.20e-01 74.5% 77.8%
1u5pA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 32.0 3.94e-01 73.9% 81.5%
6tqfA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.58 43.0 3.30e-01 76.4% 96.9%
4ocqA01 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.57 38.0 3.34e-01 83.6% 45.0%
8h72B01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.57 41.0 3.40e-01 74.5% 94.5%
3pe0A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 30.0 3.68e-01 75.8% 89.1%
1kmiZ02 1.10.287.500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.52 28.0 3.06e-01 95.2% 61.2%
4cqiA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.52 30.0 3.69e-01 95.8% 88.8%
5nl6B01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 30.0 3.48e-01 73.3% 78.5%
ECOD (38)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4377602 109.4.1.3456 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › FUSC 0.92 85.0 6.57e-01 95.8% 66.3%
3835030 604.5.1.7 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › ALMT 0.84 77.0 7.74e-01 95.2% 97.6%
3805429 3562.1.1.33 alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › ALMT 0.82 75.0 7.62e-01 95.8% 98.1%
3314927 7064.1.1.5 alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › ALMT 0.82 75.0 7.57e-01 96.4% 98.8%
3248399 3921.1.1.7 alpha complex topology › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › ALMT 0.82 76.0 5.98e-01 97.6% 67.9%
3277315 1075.1.1.59 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ALMT 0.82 76.0 5.95e-01 97.6% 68.1%
3297362 5067.1.1.13 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ALMT 0.81 76.0 7.61e-01 97.0% 97.6%
3834034 5067.1.1.13 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ALMT 0.81 75.0 7.55e-01 97.0% 96.4%
3264196 5067.1.1.13 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ALMT 0.81 74.0 7.43e-01 95.8% 95.8%
3367916 5067.1.1.13 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ALMT 0.80 72.0 7.45e-01 94.5% 100.0%
3663646 7064.1.1.5 alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › ALMT 0.79 58.0 6.60e-01 75.2% 100.0%
3175660 5067.1.1.14 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › FUSC_2 0.78 72.0 5.57e-01 97.6% 62.1%
3267773 3921.1.1.6 alpha complex topology › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › FUSC_2 0.78 70.0 5.54e-01 96.4% 66.5%
3337402 5067.1.1.14 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › FUSC_2 0.77 70.0 5.46e-01 98.2% 47.8%
3600444 7064.1.1.0 alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 0.74 62.0 6.56e-01 91.5% 100.0%
4013519 593.1.1.0 alpha bundles › GroEL equatorial domain-like › GroEL equatorial domain-like › GroEL equatorial domain-like 0.68 60.0 5.00e-01 93.3% 95.9%
4104623 1079.1.1.8 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › LysE 0.66 50.0 4.67e-01 78.2% 86.5%
4279461 593.1.1.1 alpha bundles › GroEL equatorial domain-like › GroEL equatorial domain-like › GroEL equatorial domain-like › Cpn60_TCP1 0.65 57.0 4.70e-01 93.9% 93.2%
3838292 1079.1.1.5 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › DsbD_2 0.65 49.0 4.53e-01 78.8% 82.3%
3567727 593.1.1.1 alpha bundles › GroEL equatorial domain-like › GroEL equatorial domain-like › GroEL equatorial domain-like › Cpn60_TCP1 0.64 56.0 4.73e-01 93.9% 90.0%
5003109 1079.1.1.1 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › DsbD 0.62 47.0 4.29e-01 79.4% 84.0%
3334905 3745.1.1.1 alpha bundles › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Na_Ca_ex 0.62 49.0 3.70e-01 81.8% 67.0%
3943261 5050.1.1.53 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MarC 0.59 45.0 4.14e-01 79.4% 83.7%
1148047 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.56 36.0 3.74e-01 89.7% 68.9%
3382499 3755.3.1.308 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF629 0.54 41.0 4.08e-01 93.9% 74.3%
5043808 3236.1.1.1 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.54 41.0 3.15e-01 78.8% 39.8%
3924181 3236.1.1.1 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.54 42.0 3.16e-01 82.4% 38.1%
3218650 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.54 30.0 3.75e-01 75.8% 86.7%
3748413 604.1.1.7 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › SR_plectin_7 0.54 32.0 3.76e-01 75.8% 81.7%
3675420 3755.3.1.308 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF629 0.54 42.0 3.71e-01 82.4% 75.5%
4999626 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.54 40.0 3.37e-01 77.6% 85.5%
3188194 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.53 45.0 4.09e-01 90.3% 92.9%
3588638 3236.1.1.1 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.53 41.0 3.13e-01 81.2% 36.5%
4643581 603.2.1.0 alpha bundles › STAT-like › STAT › STAT 0.52 40.0 3.71e-01 93.9% 63.7%
3286912 632.18.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › hypothetical protein PA2901 › hypothetical protein PA2901 0.52 25.0 3.25e-01 91.5% 78.9%
3689936 3236.1.1.1 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.52 40.0 2.95e-01 81.2% 36.4%
4008353 5050.1.1.10 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_2 0.51 41.0 3.00e-01 84.2% 82.7%
3833759 3684.1.1.2 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 0.50 42.0 3.84e-01 90.3% 99.6%
D4 medium residues 526-602
PDB
Domain cluster: representative
CATH (62)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4a4kA01 1.20.1500.20 Mainly Alpha › Up-down Bundle › YheA-like fold › 0.84 58.0 5.05e-01 71.4% 54.0%
3kkbA00 1.20.120.880 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase (KinB), sensor domain 0.82 75.0 6.30e-01 100.0% 66.7%
3na7A00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.82 58.0 4.01e-01 74.0% 76.4%
5j1gA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.82 75.0 5.23e-01 100.0% 82.9%
2pihA00 1.20.1500.10 Mainly Alpha › Up-down Bundle › YheA-like fold › YheA/YmcA-like 0.81 56.0 4.67e-01 71.4% 49.6%
3qc1A01 1.25.40.540 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TAP42-like family 0.80 62.0 4.91e-01 83.1% 54.3%
1m62A00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.79 71.0 6.84e-01 98.7% 93.1%
4iggB02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.78 69.0 5.97e-01 98.7% 70.2%
5jrcA00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 70.0 5.24e-01 100.0% 42.5%
3a8pA02 6.10.140.680 Special › Helix non-globular › Helix Hairpins › 0.78 61.0 5.26e-01 81.8% 68.4%
1j1jA01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.77 64.0 5.35e-01 90.9% 65.9%
2v0cA04 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.77 64.0 4.98e-01 90.9% 43.4%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.77 68.0 6.15e-01 100.0% 92.5%
3fhnA01 6.10.280.210 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain A 0.77 66.0 4.97e-01 94.8% 58.7%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.77 66.0 6.42e-01 94.8% 98.8%
1hciA03 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 66.0 5.76e-01 98.7% 91.7%
1wkbA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.75 63.0 5.39e-01 90.9% 62.8%
2qywA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.75 67.0 6.26e-01 98.7% 95.8%
1jnrA03 1.20.58.100 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain 0.75 66.0 5.75e-01 100.0% 86.0%
3caxA01 1.20.120.520 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like 0.75 65.0 4.70e-01 96.1% 48.4%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.74 62.0 5.50e-01 94.8% 68.1%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 66.0 5.09e-01 100.0% 76.3%
3nbxX03 1.20.58.1510 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 60.0 5.44e-01 87.0% 85.1%
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.74 65.0 5.27e-01 98.7% 58.5%
2crbA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.74 64.0 5.91e-01 94.8% 79.4%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.74 65.0 6.29e-01 98.7% 95.3%
3pjaJ01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.73 67.0 5.59e-01 100.0% 69.5%
2uubT00 1.20.58.110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 0.73 64.0 5.93e-01 100.0% 76.8%
1zu2A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.72 63.0 5.01e-01 100.0% 47.5%
1xioA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.72 63.0 4.57e-01 97.4% 44.7%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.72 53.0 5.00e-01 76.6% 73.6%
2mpkA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.72 56.0 5.70e-01 84.4% 97.3%
1nafA02 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 62.0 6.00e-01 96.1% 98.8%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.71 48.0 4.74e-01 70.1% 76.8%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.71 63.0 5.94e-01 100.0% 100.0%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.71 57.0 5.84e-01 88.3% 94.6%
2odmA00 1.10.287.750 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like 0.70 61.0 6.09e-01 98.7% 98.7%
3a98A02 1.20.1270.350 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Dedicator of cytokinesis N-terminal subdomain 0.70 50.0 4.78e-01 85.7% 65.5%
1j5wA02 1.20.58.180 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 0.69 61.0 6.16e-01 100.0% 100.0%
4adnA01 1.20.1280.250 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.69 54.0 5.25e-01 90.9% 76.5%
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.69 59.0 5.24e-01 100.0% 73.1%
4epzA00 1.25.40.810 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › UpxZ 0.69 53.0 4.33e-01 85.7% 42.9%
2pfdA03 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.69 59.0 4.43e-01 98.7% 47.3%
2jx0A00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.69 59.0 5.02e-01 97.4% 74.0%
1tqgA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.69 59.0 5.25e-01 92.2% 72.4%
1kt1A03 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.68 57.0 4.52e-01 92.2% 46.2%
2v6yA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.68 58.0 5.86e-01 98.7% 98.7%
3pe0A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 58.0 5.31e-01 100.0% 98.1%
2vs0A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.68 47.0 4.64e-01 72.7% 100.0%
6d5xA00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.67 59.0 4.76e-01 98.7% 94.7%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.67 58.0 5.07e-01 98.7% 74.2%
2gscC00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.67 56.0 5.05e-01 94.8% 70.9%
2y1vA04 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.66 57.0 4.34e-01 96.1% 75.1%
4wzxA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.65 54.0 5.51e-01 94.8% 100.0%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.64 51.0 4.81e-01 88.3% 74.2%
3ihvA03 1.25.40.900 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.63 54.0 4.40e-01 93.5% 100.0%
2lxlA00 1.25.40.270 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 0.62 54.0 4.32e-01 100.0% 49.7%
1foeA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.62 51.0 3.88e-01 93.5% 60.0%
4dwlA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.62 51.0 4.70e-01 97.4% 86.1%
7shlA02 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.59 47.0 4.13e-01 90.9% 95.9%
2cdqA02 1.20.120.1320 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartokinase, catalytic domain 0.58 45.0 4.27e-01 87.0% 69.1%
4h33A00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.57 41.0 3.96e-01 100.0% 65.9%
ECOD (63)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3927006 603.1.1.99 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 0.88 76.0 7.13e-01 90.9% 98.9%
3224585 603.1.1.99 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 0.87 81.0 7.02e-01 98.7% 89.1%
4511937 603.1.1.139 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE_C, PF27021 0.86 81.0 6.29e-01 100.0% 65.3%
3303315 603.1.1.3 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE 0.85 77.0 6.01e-01 96.1% 63.3%
3510367 603.1.1.99 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 0.85 79.0 6.13e-01 100.0% 63.2%
3276921 603.1.1.3 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE 0.85 79.0 6.26e-01 100.0% 66.9%
3251544 109.4.1.192 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.84 70.0 5.27e-01 90.9% 40.0%
3706209 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.84 77.0 6.11e-01 98.7% 66.2%
4066169 109.4.1.359 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exo70_C 0.84 71.0 4.08e-01 90.9% 18.0%
3816000 109.4.1.1353 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_11, TPR_16 0.84 70.0 4.69e-01 90.9% 26.2%
3302294 109.4.1.5 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1 0.84 69.0 4.67e-01 90.9% 26.2%
4018129 109.4.1.148 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › EST1_DNA_bind,EST1 0.82 76.0 4.45e-01 100.0% 15.8%
3719058 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.82 76.0 7.32e-01 100.0% 92.9%
3407072 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.82 72.0 7.18e-01 96.1% 96.2%
3829016 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.82 72.0 6.02e-01 94.8% 70.4%
3581264 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.82 75.0 6.34e-01 98.7% 82.5%
3713576 603.1.1.116 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27980 0.81 70.0 6.64e-01 93.5% 98.9%
3524429 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.81 70.0 6.35e-01 93.5% 93.0%
3401264 109.4.1.1290 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_19 0.81 66.0 4.51e-01 90.9% 26.7%
3689275 109.4.1.356 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.81 73.0 4.45e-01 100.0% 88.8%
3584478 1134.1.1.0 alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain 0.79 68.0 6.43e-01 93.5% 85.6%
3283506 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.78 66.0 5.99e-01 93.5% 76.2%
3384607 109.4.1.90 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TOM20_plant 0.78 72.0 5.17e-01 100.0% 72.2%
3648998 604.3.1.1 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG 0.78 69.0 6.60e-01 98.7% 91.1%
3232756 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.78 67.0 6.47e-01 93.5% 87.1%
3389963 1134.1.1.0 alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain 0.77 64.0 6.71e-01 92.2% 100.0%
3184710 1134.1.1.7 alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain › ALA1 0.77 61.0 6.36e-01 90.9% 92.9%
3740089 1134.1.1.7 alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain › ALA1 0.77 58.0 6.21e-01 85.7% 93.8%
3926031 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.76 66.0 6.14e-01 94.8% 80.0%
3551884 109.4.1.2087 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2, TPR_8, TPR_16, TPR_19, ARM_TT21_4th 0.75 69.0 4.27e-01 100.0% 56.6%
3596136 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.75 68.0 4.16e-01 98.7% 19.1%
4012164 1134.1.1.0 alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain 0.75 59.0 6.26e-01 94.8% 100.0%
3218730 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.74 61.0 6.18e-01 89.6% 96.0%
3724761 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.74 56.0 5.84e-01 81.8% 90.0%
3213161 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.74 63.0 4.66e-01 93.5% 43.1%
3676953 109.4.1.87 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec6 0.74 64.0 3.75e-01 100.0% 13.3%
3624728 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.73 65.0 6.31e-01 98.7% 92.9%
3739242 3291.1.1.1 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 0.73 64.0 4.81e-01 92.2% 89.1%
3329616 109.4.1.359 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exo70_C 0.73 64.0 4.71e-01 100.0% 37.1%
4022775 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.73 65.0 3.74e-01 94.8% 35.1%
3720908 109.4.1.22 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N 0.72 52.0 3.44e-01 77.9% 18.2%
3245731 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.71 60.0 6.00e-01 94.8% 97.5%
3473134 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.71 62.0 4.73e-01 96.1% 62.3%
5072449 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.70 62.0 5.90e-01 98.7% 90.0%
3188613 604.12.1.2 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 0.70 62.0 5.68e-01 97.4% 88.0%
3694135 109.4.1.356 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.69 61.0 4.09e-01 100.0% 45.2%
1146575 109.39.1.1 alpha superhelices › Repetitive alpha hairpins › transcription anti-terminator antagonist UpxZ › transcription anti-terminator antagonist UpxZ › UpxZ 0.69 53.0 4.33e-01 85.7% 42.9%
4681537 3718.1.1.1 alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT › FliT 0.67 58.0 5.40e-01 98.7% 81.0%
3994389 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.67 59.0 3.89e-01 98.7% 27.2%
3276944 604.12.1.2 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 0.67 56.0 5.70e-01 94.8% 96.0%
3264196 5067.1.1.13 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ALMT 0.67 53.0 4.18e-01 87.0% 77.0%
4990309 150.2.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Cobalamin adenosyltransferase › Cobalamin adenosyltransferase › Cob_adeno_trans 0.66 55.0 4.40e-01 94.8% 87.9%
3925416 109.4.1.1361 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_CAND1 0.65 52.0 3.82e-01 89.6% 35.6%
4024570 604.12.1.2 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 0.65 55.0 5.14e-01 94.8% 82.1%
3186555 109.4.1.22 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N 0.65 51.0 3.11e-01 90.9% 12.9%
3108769 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.65 52.0 5.40e-01 94.8% 98.6%
4943123 604.12.1.134 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › AAA 0.63 53.0 5.24e-01 98.7% 90.6%
3499593 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.63 52.0 5.22e-01 97.4% 92.5%
4946174 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.60 48.0 4.55e-01 88.3% 72.2%
4947816 601.28.1.0 alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like 0.59 49.0 4.59e-01 97.4% 78.0%
3231747 6155.1.1.7 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › CLPTM1 0.58 51.0 3.60e-01 98.7% 35.6%
4997044 601.28.1.0 alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like 0.55 47.0 4.35e-01 100.0% 76.2%
4024393 6155.1.1.2 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.54 46.0 4.56e-01 97.4% 98.8%
D5 medium residues 603-686
PDB
Domain cluster: representative
CATH (48)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3onjA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.89 73.0 6.91e-01 85.7% 88.7%
2v6yA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.86 68.0 7.18e-01 88.1% 92.0%
2qywA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.84 72.0 6.90e-01 90.5% 91.6%
2bvlA01 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.83 63.0 6.31e-01 94.0% 77.9%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.83 70.0 6.02e-01 90.5% 65.6%
3kkbA00 1.20.120.880 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase (KinB), sensor domain 0.79 66.0 5.70e-01 88.1% 58.7%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.79 52.0 4.91e-01 88.1% 56.0%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.79 67.0 6.37e-01 90.5% 84.7%
2pfdA03 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.78 71.0 5.31e-01 100.0% 75.9%
6t0bc02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.78 67.0 5.09e-01 92.9% 64.4%
4cqiA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 65.0 5.95e-01 88.1% 100.0%
2ra1A02 1.20.58.780 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 59.0 6.40e-01 79.8% 100.0%
2ra1A01 1.20.58.790 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 64.0 6.12e-01 89.3% 83.7%
3lmfA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.77 66.0 6.06e-01 94.0% 75.2%
4hwhE00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.77 64.0 6.35e-01 90.5% 89.8%
5figA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.76 66.0 6.25e-01 95.2% 80.0%
2uxwA04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.76 52.0 4.46e-01 70.2% 54.6%
8f76A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.76 65.0 4.35e-01 91.7% 69.2%
2crbA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.75 59.0 5.62e-01 94.0% 73.2%
3ucaA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.75 64.0 4.38e-01 91.7% 82.5%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.74 57.0 5.72e-01 84.5% 81.2%
4l8iB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.74 63.0 5.69e-01 91.7% 89.3%
1wcrA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.74 61.0 5.69e-01 89.3% 87.4%
3ismC01 1.25.40.240 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ku, C-terminal domain 0.74 61.0 4.98e-01 90.5% 53.9%
5dqqA01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.74 65.0 5.57e-01 95.2% 68.8%
1vcsA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.73 58.0 5.45e-01 85.7% 77.5%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 60.0 5.11e-01 90.5% 72.1%
3nbxX03 1.20.58.1510 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 61.0 5.75e-01 92.9% 87.1%
3cqcB01 1.20.58.1380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 50.0 4.94e-01 88.1% 67.8%
3m6jA01 1.20.1260.40 Mainly Alpha › Up-down Bundle › Ferritin › 0.71 59.0 5.27e-01 90.5% 94.9%
1sumB02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.70 61.0 5.50e-01 97.6% 89.8%
5jrcA00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 61.0 4.70e-01 95.2% 48.4%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 57.0 5.28e-01 90.5% 88.2%
2b1eA01 1.20.58.1150 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 53.0 5.29e-01 85.7% 79.1%
2fupA00 1.20.58.300 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like 0.70 61.0 5.23e-01 92.9% 91.3%
1jogA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.69 58.0 4.91e-01 90.5% 85.9%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.68 54.0 5.41e-01 88.1% 85.9%
4it4A02 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.68 54.0 5.29e-01 85.7% 80.2%
2p5tA00 1.10.8.130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.67 45.0 4.45e-01 70.2% 67.4%
4b94A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.67 54.0 4.54e-01 92.9% 51.8%
4k7bA00 1.20.120.1740 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Sodium ion translocating NADH-quinone reductase subunit C-like 0.66 49.0 4.57e-01 91.7% 61.3%
2d2sA01 1.20.58.1210 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain 0.66 55.0 4.89e-01 90.5% 79.3%
4wqoD00 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.65 54.0 4.59e-01 91.7% 86.5%
2oerA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.65 57.0 4.46e-01 96.4% 63.1%
3c18A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.63 56.0 4.93e-01 95.2% 68.6%
4zvaA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.62 53.0 4.43e-01 94.0% 85.9%
1hu3A00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.61 47.0 3.55e-01 83.3% 39.2%
4bpxD00 1.20.930.80 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › 0.56 46.0 3.50e-01 92.9% 83.1%
ECOD (54)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3514842 603.1.1.3 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE 0.85 71.0 6.53e-01 88.1% 81.0%
3591222 604.1.1.198 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › BAG 0.84 73.0 6.99e-01 91.7% 87.4%
3703141 109.4.1.3264 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Flagellar_rod 0.84 76.0 5.42e-01 96.4% 71.1%
54315 633.16.1.0 alpha bundles › Bromodomain-like › PMT helical bundle domain-like › PMT helical bundle domain-like 0.83 63.0 6.19e-01 94.0% 74.4%
5082279 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.81 70.0 6.10e-01 91.7% 67.5%
4358621 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.81 62.0 6.39e-01 90.5% 84.8%
3227250 601.3.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain 0.81 69.0 5.57e-01 91.7% 97.4%
3592036 3291.1.1.16 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Flagellar_rod 0.80 72.0 5.32e-01 97.6% 78.6%
3892002 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.80 72.0 5.79e-01 96.4% 100.0%
3699444 3755.3.1.6 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Flagellar_rod 0.80 72.0 5.26e-01 97.6% 74.4%
5061228 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.80 65.0 6.12e-01 86.9% 82.0%
4949854 601.18.1.0 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 0.80 67.0 6.06e-01 90.5% 68.1%
3962252 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.80 66.0 5.39e-01 89.3% 52.0%
3577937 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.79 66.0 5.91e-01 89.3% 77.4%
3608075 603.1.1.218 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Flagellar_rod 0.78 69.0 5.39e-01 95.2% 80.0%
3828970 604.3.1.1 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG 0.78 65.0 6.28e-01 90.5% 83.2%
3725456 604.3.1.24 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › PF27980 0.78 63.0 6.30e-01 86.9% 98.8%
2813237 633.21.1.1 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › DUF326 0.77 67.0 6.13e-01 95.2% 76.9%
3590053 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.77 61.0 6.12e-01 90.5% 83.5%
4975245 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.77 63.0 6.28e-01 90.5% 85.2%
3333216 604.3.1.1 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG 0.76 63.0 6.08e-01 90.5% 83.2%
3716214 3755.3.1.6 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Flagellar_rod 0.76 59.0 4.52e-01 81.0% 62.9%
3734418 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.75 62.0 4.12e-01 90.5% 38.8%
None 0.75 60.0 6.36e-01 90.5% 96.0%
3938725 109.4.1.1276 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › FAT, HEAT_ATR 0.75 64.0 4.34e-01 94.0% 48.5%
4982185 604.12.1.144 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › PF27307 0.74 60.0 5.58e-01 86.9% 87.5%
3926978 109.4.1.148 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › EST1_DNA_bind,EST1 0.74 61.0 3.63e-01 90.5% 16.9%
3312027 603.1.1.156 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PGG 0.74 65.0 5.56e-01 95.2% 81.5%
3678146 604.3.1.1 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG 0.73 63.0 5.36e-01 96.4% 77.1%
3498448 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.73 60.0 6.11e-01 90.5% 93.8%
3964011 633.21.1.1 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › DUF326 0.72 64.0 5.87e-01 98.8% 81.8%
3226751 604.3.1.13 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › DUF19 0.72 56.0 4.62e-01 88.1% 47.3%
3333578 109.4.1.578 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF3730 0.71 62.0 4.90e-01 96.4% 49.1%
5070202 109.4.1.210 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_19 0.71 64.0 4.97e-01 96.4% 49.4%
5030299 633.16.1.0 alpha bundles › Bromodomain-like › PMT helical bundle domain-like › PMT helical bundle domain-like 0.71 59.0 6.03e-01 86.9% 95.0%
3403082 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.70 63.0 4.70e-01 98.8% 56.7%
4028818 603.1.1.17 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE 0.70 63.0 4.64e-01 98.8% 85.7%
3725615 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.70 55.0 5.65e-01 90.5% 91.3%
3406711 632.11.1.2 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like › DOCK_N 0.69 54.0 5.39e-01 100.0% 80.0%
3321233 604.12.1.2 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 0.69 52.0 5.25e-01 95.2% 80.0%
4032823 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.69 56.0 5.76e-01 89.3% 95.0%
3240455 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.68 55.0 5.46e-01 90.5% 95.6%
4978936 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.68 55.0 4.21e-01 89.3% 54.5%
3626462 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.67 56.0 5.03e-01 90.5% 92.2%
3591867 3543.1.1.6 alpha complex topology › Acid-activated urea channel › Acid-activated urea channel › Acid-activated urea channel › PEX11 0.67 60.0 4.40e-01 98.8% 61.8%
5051493 109.3.1.473 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › TPR_8 0.67 59.0 4.00e-01 94.0% 32.9%
3772686 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.66 58.0 3.87e-01 98.8% 68.1%
3791248 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.65 56.0 4.39e-01 96.4% 71.4%
3663421 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.65 60.0 3.59e-01 100.0% 50.2%
5061713 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.65 57.0 3.82e-01 95.2% 28.9%
3867041 109.3.1.6 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › TRP_2 0.62 52.0 3.60e-01 92.9% 27.2%
4116939 2004.1.1.525 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23, AAA_27, SbcC_Walker_B 0.60 54.0 3.32e-01 100.0% 24.1%
3595100 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.58 48.0 4.54e-01 91.7% 94.0%
3347270 3843.1.1.0 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.52 46.0 4.30e-01 98.8% 83.8%