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CAKLQF020000006.1__CAH1079910.1__SAMEA5780031_01433__00075

Bact-Vir

CAKLQF020000006.1__CAH1079910.1__SAMEA5780031_01433__00075

Identity

Kingdom:
phage

Quality

83.5 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-78_95-113_145-181
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01810.25 best LysE 35.2 1.30e-08 52.2% 33.2%
CATH (25)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6ynwH01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.64 33.0 4.29e-01 76.9% 89.2%
2zy9A03 1.10.357.20 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › SLC41 divalent cation transporters, integral membrane domain 0.63 47.0 4.34e-01 97.8% 60.3%
7dwqL01 1.20.1240.10 Mainly Alpha › Up-down Bundle › Photosystem 1 Reaction Centre Subunit Xi; Chain: L; › Photosystem I PsaL, reaction centre subunit XI 0.63 49.0 5.06e-01 94.8% 88.0%
4lqkA00 1.10.437.20 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › dsDNA poxvirus 0.62 32.0 3.32e-01 91.8% 50.0%
1st6A04 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.62 39.0 4.18e-01 84.3% 72.6%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.61 35.0 3.69e-01 77.6% 60.7%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.60 38.0 4.11e-01 85.1% 73.5%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.60 38.0 3.88e-01 83.6% 63.4%
1quuA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 40.0 4.14e-01 82.1% 72.2%
1hs7A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 35.0 4.02e-01 81.3% 79.4%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.59 38.0 4.24e-01 83.6% 82.2%
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.58 35.0 3.71e-01 84.3% 66.4%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 39.0 3.90e-01 82.1% 66.9%
4x28A01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.55 34.0 3.64e-01 88.8% 70.8%
3ddlA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.54 40.0 3.26e-01 77.6% 85.3%
7dfeA01 1.10.274.60 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain 0.54 31.0 3.24e-01 89.6% 59.1%
3v0aB02 1.20.1120.10 Mainly Alpha › Up-down Bundle › "Clostridium botulinum neurotoxin B, ""coiled-coil"" domain" › "Clostridium botulinum neurotoxin b, ""coiled-coil"" domain" 0.54 47.0 3.52e-01 95.5% 59.2%
4bjaA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.52 47.0 4.20e-01 96.3% 92.3%
2gtaA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.52 31.0 3.57e-01 85.8% 79.4%
1hciA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.52 36.0 3.69e-01 81.3% 74.6%
1wkbA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.52 32.0 3.37e-01 91.0% 66.9%
7p3rA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.51 41.0 3.14e-01 87.3% 99.4%
2l81A00 1.20.120.830 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain 0.51 39.0 3.56e-01 84.3% 60.8%
2nrjA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.51 43.0 3.23e-01 91.0% 90.9%
3ucaA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.51 32.0 2.56e-01 82.1% 29.9%
ECOD (44)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3968454 1079.1.1.8 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › LysE 0.84 78.0 6.59e-01 97.0% 88.3%
3278851 3538.1.1.4 extended segments › MerF › MerF › MerF › LysE 0.82 78.0 6.54e-01 99.3% 87.5%
3281450 5086.1.1.183 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › LysE 0.72 65.0 6.61e-01 93.3% 100.0%
4562109 1079.1.1.0 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA 0.72 67.0 6.34e-01 98.5% 98.7%
3253929 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.71 44.0 4.67e-01 85.1% 70.0%
3667987 1079.1.1.0 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA 0.69 65.0 5.58e-01 100.0% 83.5%
5003109 1079.1.1.1 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › DsbD 0.69 62.0 5.24e-01 100.0% 88.4%
3839115 1079.1.1.8 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › LysE 0.68 64.0 5.45e-01 100.0% 87.8%
4060033 1079.1.1.0 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA 0.68 63.0 5.39e-01 100.0% 93.3%
4169514 5050.1.1.54 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Mntp 0.68 63.0 5.60e-01 99.3% 87.6%
3935488 5051.1.1.6 alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Aa_trans 0.67 61.0 4.32e-01 99.3% 65.6%
4958934 1079.1.1.8 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › LysE 0.66 62.0 5.44e-01 100.0% 88.4%
4662559 1079.1.1.0 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA 0.65 59.0 4.75e-01 97.0% 88.2%
4955097 1188.1.1.3 alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter › Mntp 0.64 58.0 5.23e-01 100.0% 89.2%
3253937 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.63 40.0 4.25e-01 85.1% 70.8%
3952992 1079.1.1.7 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › SfLAP 0.63 57.0 5.30e-01 98.5% 90.0%
4223336 1079.1.1.0 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA 0.63 57.0 4.94e-01 97.0% 86.0%
5084032 5050.1.1.53 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MarC 0.63 56.0 4.81e-01 97.8% 82.2%
4554168 1079.1.1.13 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Mntp 0.62 58.0 5.23e-01 99.3% 86.9%
4989697 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.62 52.0 4.70e-01 100.0% 67.2%
5078462 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.61 57.0 4.47e-01 100.0% 50.2%
5058529 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.61 52.0 4.45e-01 96.3% 59.0%
5050364 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.60 56.0 4.83e-01 100.0% 69.5%
4985682 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.60 54.0 5.39e-01 96.3% 97.0%
4972695 7064.1.1.1 alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 0.59 52.0 4.63e-01 92.5% 87.2%
3506410 604.13.1.1 alpha bundles › Spectrin repeat-like › USP8 N-terminal domain-like › USP8 N-terminal domain-like › USP8_dimer 0.59 33.0 3.41e-01 94.8% 55.4%
5018146 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.59 54.0 4.37e-01 99.3% 56.8%
4208599 1002.1.1.1 alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB 0.57 39.0 3.94e-01 91.0% 69.2%
3760737 601.16.1.17 alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › PF27561 0.57 38.0 3.79e-01 84.3% 64.3%
4009525 628.1.1.1 alpha bundles › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › FCD 0.57 41.0 3.96e-01 73.9% 100.0%
5028340 3236.1.1.1 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.57 38.0 2.73e-01 91.0% 23.0%
3638493 601.16.1.0 alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase 0.56 37.0 3.49e-01 84.3% 55.0%
3601375 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 38.0 3.22e-01 85.8% 41.3%
3734873 601.14.1.1 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.54 37.0 3.00e-01 79.9% 37.1%
3963135 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.53 44.0 3.93e-01 88.8% 67.4%
4977934 1076.1.1.0 alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related 0.53 42.0 3.48e-01 91.8% 47.5%
3567414 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.51 38.0 3.81e-01 82.8% 76.3%
3498332 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.51 40.0 3.88e-01 82.8% 91.3%
5079638 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.51 29.0 3.36e-01 82.1% 76.0%
3735933 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.51 43.0 4.26e-01 91.8% 96.6%
2966920 5037.1.1.2 alpha bundles › Bacterial photosystem II reaction centre L and M subunits-like › Bacterial photosystem II reaction centre L and M subunits-like › Bacterial photosystem II reaction centre L and M subunits-like › PsaA_PsaB 0.51 40.0 3.09e-01 83.6% 47.4%
3663646 7064.1.1.5 alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › ALMT 0.50 41.0 4.22e-01 85.8% 100.0%
5081189 5059.1.1.0 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter 0.50 35.0 3.47e-01 97.0% 67.1%
5071393 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.50 37.0 3.59e-01 97.0% 68.0%
D2 medium residues 79-94_114-144_182-205
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01810.25 best LysE 28.5 1.40e-06 64.8% 16.6%
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4l8jA04 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.69 45.0 4.91e-01 100.0% 81.4%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.63 43.0 4.06e-01 100.0% 58.8%
3ck6C02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.62 48.0 3.96e-01 81.7% 79.8%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.61 41.0 3.87e-01 100.0% 57.5%
1vf7A03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.59 35.0 3.78e-01 100.0% 70.0%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.57 44.0 3.68e-01 81.7% 82.2%
3pe0A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 44.0 3.81e-01 81.7% 87.7%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.56 37.0 3.56e-01 100.0% 58.8%
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.55 45.0 3.51e-01 87.3% 69.4%
4gkfA00 1.10.520.30 Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › AF1862-like domain 0.54 48.0 3.82e-01 100.0% 76.0%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.54 40.0 3.53e-01 80.3% 85.8%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.53 45.0 3.88e-01 100.0% 60.7%
5hayA02 1.25.40.440 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Nucleoporin, helical domain, central subdomain 0.52 36.0 3.55e-01 73.2% 98.7%
3rguB00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.52 39.0 3.70e-01 83.1% 95.4%
4okvE00 6.10.140.1890 Special › Helix non-globular › Helix Hairpins › 0.51 38.0 4.04e-01 100.0% 86.2%
4dwlA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.51 40.0 3.45e-01 83.1% 67.6%
1rp3G02 1.20.140.160 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › PhyR, sigma-like (SL) domain 0.51 44.0 3.58e-01 98.6% 93.0%
2ot4A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.51 39.0 3.42e-01 83.1% 80.4%
2x2vA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.51 42.0 4.30e-01 98.6% 92.6%
2zxqA06 1.20.1270.70 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle 0.50 39.0 4.04e-01 84.5% 98.5%
1dk8A02 1.10.167.10 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 0.50 43.0 4.15e-01 100.0% 95.3%
ECOD (9)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3924442 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.67 41.0 3.53e-01 100.0% 40.0%
3624728 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.62 41.0 3.83e-01 100.0% 56.5%
3633174 604.1.1.55 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › RasGAP_C 0.59 46.0 4.09e-01 83.1% 81.0%
5029063 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.59 42.0 2.84e-01 76.1% 51.4%
4013477 1025.1.1.0 alpha bundles › Stonustoxin helical domain › Stonustoxin helical domain › Stonustoxin helical domain 0.59 46.0 3.94e-01 83.1% 89.1%
4561291 632.22.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA 0.57 44.0 3.84e-01 81.7% 91.4%
4982026 150.1.1.209 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › DUF7121 0.55 40.0 3.25e-01 78.9% 55.7%
4993414 3563.1.1.1 alpha bundles › Twin arginine protein translocation system component TatC › Twin arginine protein translocation system component TatC › Twin arginine protein translocation system component TatC › TatC 0.55 37.0 2.56e-01 70.4% 63.9%
5040466 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.52 35.0 3.46e-01 100.0% 66.2%