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CAKLQF020000006.1__CAH1079931.1__SAMEA5780031_01440__00082
Bact-VirCAKLQF020000006.1__CAH1079931.1__SAMEA5780031_01440__00082
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 9-217
Domain cluster:
rep: IMGVR_UViG_3300001567_000010-3300001567-Draft_1000075920__D1-206
CATH (33)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4mk6A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.71 | 40.0 | 4.22e-01 | 81.8% | 60.6% |
| 1j8yF01 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.70 | 31.0 | 4.60e-01 | 77.0% | 97.7% |
| 2iu5B00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.70 | 38.0 | 4.11e-01 | 89.5% | 61.0% |
| 1c17M00 | 1.20.120.220 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ATP synthase, F0 complex, subunit A | 0.68 | 46.0 | 5.44e-01 | 92.3% | 98.6% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.68 | 33.0 | 4.48e-01 | 87.1% | 88.0% |
| 3vr4B04 | 1.10.1140.10 | Mainly Alpha › Orthogonal Bundle › Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain; Chain D, domain3 › Bovine Mitochondrial F1-atpase; Atp Synthase Beta Chain; Chain D, domain 3 | 0.68 | 32.0 | 3.74e-01 | 82.8% | 60.9% |
| 4f4cA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.66 | 57.0 | 3.89e-01 | 92.3% | 72.3% |
| 3crjC00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.64 | 37.0 | 4.02e-01 | 83.7% | 64.8% |
| 3bhqA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.64 | 39.0 | 4.00e-01 | 87.6% | 60.9% |
| 1zkeA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 26.0 | 4.20e-01 | 85.6% | 98.8% |
| 1jadA00 | 1.20.1230.10 | Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain | 0.63 | 47.0 | 4.51e-01 | 76.6% | 94.6% |
| 4tkrA00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.63 | 36.0 | 3.84e-01 | 90.4% | 61.7% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.63 | 40.0 | 4.92e-01 | 73.7% | 99.2% |
| 4bejB02 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.62 | 56.0 | 5.53e-01 | 100.0% | 92.8% |
| 3s84A02 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.61 | 44.0 | 5.00e-01 | 79.4% | 97.5% |
| 4fjqA01 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.61 | 42.0 | 3.44e-01 | 85.2% | 39.7% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.59 | 37.0 | 4.44e-01 | 90.0% | 96.2% |
| 1wmwB00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.59 | 40.0 | 3.43e-01 | 87.6% | 43.9% |
| 3t9oB00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.59 | 34.0 | 4.29e-01 | 91.9% | 95.8% |
| 2b5uA02 | 1.10.287.620 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins | 0.59 | 31.0 | 3.50e-01 | 93.8% | 65.2% |
| 2nx4C00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.59 | 34.0 | 3.58e-01 | 84.7% | 61.0% |
| 3mpiA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.57 | 28.0 | 3.58e-01 | 82.8% | 77.7% |
| 4yjwA00 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.56 | 35.0 | 4.07e-01 | 91.4% | 85.0% |
| 1f1mA00 | 1.20.120.240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 | 0.54 | 36.0 | 4.05e-01 | 91.9% | 85.8% |
| 1yjgA00 | 1.20.120.240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 | 0.54 | 36.0 | 4.08e-01 | 91.9% | 89.2% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.52 | 30.0 | 3.44e-01 | 84.2% | 73.5% |
| 2wdqC00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.52 | 28.0 | 3.63e-01 | 77.5% | 90.1% |
| 1cnt200 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.52 | 32.0 | 3.90e-01 | 83.7% | 96.9% |
| 1q16C01 | 1.20.950.20 | Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C | 0.51 | 34.0 | 3.41e-01 | 81.8% | 64.0% |
| 1fntc01 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.51 | 38.0 | 3.96e-01 | 93.3% | 85.1% |
| 5tl8A00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.50 | 42.0 | 3.30e-01 | 89.0% | 67.6% |
| 2ijeS00 | 1.10.840.10 | Mainly Alpha › Orthogonal Bundle › Son of Sevenless (SoS) protein; Chain S, domain 2 › Ras guanine-nucleotide exchange factors catalytic domain | 0.50 | 38.0 | 3.64e-01 | 77.0% | 86.5% |
| 3fhnA01 | 6.10.280.210 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain A | 0.50 | 28.0 | 3.05e-01 | 86.1% | 61.4% |
ECOD (37)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3946757 | 601.19.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Phage_Mu_F | 0.79 | 61.0 | 5.98e-01 | 86.1% | 74.2% |
| 4032640 | 601.19.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Phage_Mu_F | 0.78 | 75.0 | 6.44e-01 | 100.0% | 78.1% |
| 1546262 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.68 | 56.0 | 5.93e-01 | 99.0% | 96.3% |
| 5064029 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.67 | 47.0 | 4.91e-01 | 75.1% | 75.9% |
| 3274502 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.66 | 62.0 | 5.10e-01 | 99.5% | 61.1% |
| 3495555 | 5079.1.1.0 ↗ | alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain | 0.65 | 53.0 | 5.30e-01 | 95.7% | 83.3% |
| 3294656 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.63 | 30.0 | 2.45e-01 | 96.2% | 24.6% |
| 4959549 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.63 | 39.0 | 4.15e-01 | 91.9% | 68.6% |
| 4946169 | 7064.1.1.0 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 | 0.62 | 47.0 | 4.77e-01 | 86.1% | 79.4% |
| 3175468 | 109.4.1.119 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TRF | 0.62 | 35.0 | 3.32e-01 | 78.9% | 44.4% |
| 4956930 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.61 | 33.0 | 3.20e-01 | 95.7% | 45.8% |
| 3282000 | 3615.1.1.0 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain | 0.60 | 55.0 | 4.66e-01 | 100.0% | 60.9% |
| 3774515 | 1075.1.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_3 | 0.60 | 51.0 | 4.57e-01 | 98.1% | 65.1% |
| 3731685 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.58 | 47.0 | 5.00e-01 | 91.9% | 95.7% |
| 5022368 | 1075.5.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt | 0.58 | 41.0 | 4.20e-01 | 90.4% | 72.2% |
| 4380034 | 1075.5.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt | 0.58 | 42.0 | 4.13e-01 | 91.9% | 68.6% |
| 5048539 | 1075.5.1.8 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 | 0.57 | 40.0 | 3.98e-01 | 90.0% | 67.4% |
| 4652128 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.56 | 41.0 | 4.13e-01 | 93.8% | 72.9% |
| 4983398 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.56 | 34.0 | 3.57e-01 | 90.4% | 63.7% |
| 4998150 | 1075.5.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt | 0.56 | 40.0 | 4.01e-01 | 90.4% | 69.8% |
| 3973659 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.56 | 45.0 | 3.16e-01 | 94.3% | 27.1% |
| 3373563 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.55 | 41.0 | 3.89e-01 | 90.9% | 63.3% |
| 5058662 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.55 | 41.0 | 4.08e-01 | 90.9% | 71.8% |
| 4202769 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.55 | 40.0 | 4.08e-01 | 94.3% | 74.8% |
| 3653914 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.55 | 40.0 | 3.85e-01 | 90.9% | 63.7% |
| 3882432 | 3758.1.1.0 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins | 0.55 | 44.0 | 3.62e-01 | 83.7% | 89.3% |
| 4962588 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.55 | 40.0 | 3.95e-01 | 90.9% | 69.3% |
| 5046307 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.54 | 38.0 | 3.80e-01 | 90.4% | 67.9% |
| 3922539 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.54 | 37.0 | 3.38e-01 | 85.2% | 49.7% |
| 3293363 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.54 | 41.0 | 3.98e-01 | 78.0% | 84.8% |
| 4026287 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.53 | 40.0 | 3.87e-01 | 87.1% | 67.1% |
| 4458494 | 3684.1.1.23 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › CA109-like | 0.53 | 39.0 | 4.26e-01 | 86.6% | 91.4% |
| 4030773 | 1075.5.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt | 0.53 | 41.0 | 3.96e-01 | 93.8% | 71.1% |
| 3971610 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.53 | 41.0 | 4.07e-01 | 80.4% | 86.8% |
| 3746558 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.52 | 32.0 | 3.24e-01 | 97.6% | 59.5% |
| 3535926 | 192.29.1.25 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › CA109-like | 0.51 | 39.0 | 4.21e-01 | 88.5% | 93.7% |
| 3697423 | 192.29.1.145 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › SHR3_chaperone | 0.50 | 34.0 | 3.96e-01 | 88.5% | 96.0% |
D2
medium
residues 219-306
Domain cluster:
rep: KY606587.1__ARB06098.1__vBDshSR5C_44__00044__D213-301
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04233.20 best | Phage_Mu_F | 34.7 | 3.70e-08 | 54.5% | 41.1% |
D3
medium
residues 307-368
Domain cluster:
rep: KR093632.1__AKI27357.1__X__00019__D263-326