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CAKLQF020000006.1__CAH1080356.1__SAMEA5780031_01570__00211

Bact-Vir

CAKLQF020000006.1__CAH1080356.1__SAMEA5780031_01570__00211

Identity

Kingdom:
phage

Quality

97.2 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 3-151
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02670.23 best DXP_reductoisom 152.7 1.20e-44 86.6% 100.0%
CATH (90)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1q0qA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.98 96.0 9.61e-01 100.0% 99.3%
6mh4A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.95 89.0 9.12e-01 100.0% 99.3%
4kp7A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.94 92.0 9.04e-01 100.0% 99.4%
3a06B01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.93 85.0 8.73e-01 100.0% 98.6%
2jcxA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.93 85.0 8.75e-01 100.0% 98.6%
6o15A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.85 65.0 7.25e-01 100.0% 98.3%
3q2iA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.84 66.0 6.39e-01 100.0% 74.1%
3e82B01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.84 64.0 6.53e-01 100.0% 80.8%
3fhlA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.83 64.0 6.64e-01 100.0% 85.5%
3ec7A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.82 65.0 5.71e-01 100.0% 57.7%
3ohsX01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.81 63.0 6.99e-01 98.7% 99.2%
3mtjA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.80 66.0 6.16e-01 100.0% 70.9%
3evnA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.80 60.0 6.73e-01 98.7% 99.1%
4pg4A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.79 65.0 6.37e-01 100.0% 79.4%
4gqaD01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.79 65.0 6.89e-01 100.0% 94.8%
4ydrA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.76 63.0 6.04e-01 100.0% 76.6%
4wesB04 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.76 49.0 5.98e-01 82.6% 100.0%
4xb1A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.74 65.0 6.04e-01 100.0% 75.1%
4isbA01 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.74 50.0 3.59e-01 100.0% 25.5%
3do5A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.73 64.0 6.01e-01 100.0% 77.6%
4inaA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.73 65.0 5.87e-01 100.0% 71.4%
3c8mA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.73 66.0 6.31e-01 100.0% 83.9%
3r5tA01 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.73 45.0 5.12e-01 81.9% 81.6%
4rlqA01 3.40.50.980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.72 45.0 3.79e-01 100.0% 38.2%
3cw9A01 3.40.50.980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.72 40.0 3.77e-01 100.0% 45.4%
1mdbA01 3.40.50.980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.72 44.0 4.38e-01 100.0% 58.2%
3etcA01 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.71 49.0 3.43e-01 100.0% 23.3%
3b7wA01 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.71 50.0 3.53e-01 100.0% 24.9%
2v7bA01 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.71 50.0 3.60e-01 100.0% 27.3%
4fuqC01 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.70 48.0 3.47e-01 100.0% 26.3%
4oo3A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.70 60.0 6.15e-01 98.7% 93.8%
3crnA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.70 47.0 5.01e-01 100.0% 78.3%
7pvaB01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.70 46.0 5.07e-01 99.3% 83.2%
4wv3B01 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.69 49.0 3.52e-01 100.0% 26.2%
1h1lD03 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.69 51.0 5.39e-01 100.0% 85.0%
4gvpA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.69 47.0 4.22e-01 100.0% 50.0%
1lciA01 3.40.50.980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.69 42.0 4.25e-01 100.0% 59.5%
1ebfA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.69 60.0 5.62e-01 100.0% 76.0%
2qsjB00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.69 44.0 4.81e-01 100.0% 77.9%
1pswA01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.69 51.0 5.26e-01 99.3% 80.4%
4w8oB00 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.68 47.0 3.38e-01 100.0% 25.5%
3rosA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.67 54.0 4.41e-01 100.0% 47.0%
3grzB00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.67 57.0 5.27e-01 94.6% 71.0%
3qyaA00 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.67 47.0 3.33e-01 100.0% 24.8%
1up7A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.66 57.0 5.94e-01 98.7% 98.5%
4jgiB02 3.40.50.280 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cobalamin-binding domain 0.66 47.0 5.08e-01 100.0% 85.7%
1j6uA03 3.90.190.20 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain 0.66 50.0 5.31e-01 96.0% 90.2%
3ntvA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.66 58.0 5.17e-01 95.3% 78.6%
6mprB01 3.40.1080.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaconate Coenzyme A-transferase › Glutaconate Coenzyme A-transferase 0.66 60.0 5.36e-01 100.0% 79.1%
5je6A01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.65 56.0 4.87e-01 94.6% 84.1%
4r0mB01 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.64 49.0 3.50e-01 100.0% 27.7%
1reqA02 3.40.50.280 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cobalamin-binding domain 0.64 46.0 4.48e-01 100.0% 67.1%
1y8cA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.64 55.0 5.18e-01 94.6% 76.9%
3gqwB01 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.64 48.0 3.43e-01 100.0% 26.8%
2nxcA03 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.64 53.0 5.33e-01 94.6% 88.9%
3bkwB00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.62 54.0 4.80e-01 95.3% 86.1%
5c3mC01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.62 57.0 5.52e-01 98.7% 99.4%
5h02A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.62 54.0 5.09e-01 94.6% 82.0%
1jg1A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.62 54.0 4.74e-01 95.3% 64.7%
1x7dA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.62 58.0 5.55e-01 100.0% 97.1%
2esrA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.62 52.0 5.17e-01 94.6% 85.6%
1xcjA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.61 54.0 4.68e-01 96.0% 82.1%
2zsgA01 3.40.350.10 Alpha Beta › 3-Layer(aba) Sandwich › Creatine Amidinohydrolase; Chain A, domain 1 › Creatinase/prolidase N-terminal domain 0.61 43.0 4.55e-01 71.1% 91.4%
3frhA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.61 53.0 4.99e-01 96.0% 79.2%
2gm3A00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.60 48.0 4.79e-01 83.2% 91.5%
4hh3C02 3.40.50.280 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cobalamin-binding domain 0.60 44.0 4.65e-01 100.0% 84.8%
2q5cA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.60 37.0 4.42e-01 97.3% 92.8%
2q5cA02 3.40.50.10660 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › PrpR receptor domain-like 0.58 35.0 4.30e-01 78.5% 100.0%
1kjnA00 3.40.50.10160 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › MTH777-like 0.57 46.0 4.62e-01 100.0% 84.2%
5ywwA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 42.0 3.89e-01 100.0% 60.4%
4ifeA02 3.30.420.240 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.57 40.0 3.49e-01 72.5% 77.5%
3l0gA02 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.57 39.0 3.95e-01 76.5% 68.6%
7pliF02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 49.0 4.88e-01 94.0% 94.0%
3huuC02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.55 43.0 4.56e-01 95.3% 93.2%
4c5yA02 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.55 48.0 3.74e-01 94.0% 65.1%
1j09A01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.55 41.0 4.46e-01 100.0% 95.9%
3a9uA02 3.40.50.980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.54 37.0 3.76e-01 94.6% 70.1%
4mp8A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 48.0 4.60e-01 99.3% 100.0%
1vliA01 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.54 47.0 3.82e-01 96.6% 72.0%
3e53A00 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.54 46.0 3.38e-01 94.6% 35.8%
1mjhB00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.54 47.0 4.81e-01 100.0% 97.9%
4hheA01 3.40.50.10800 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NadA-like 0.53 36.0 4.05e-01 89.9% 92.7%
3ivrA00 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.53 44.0 3.27e-01 89.3% 77.2%
6ulwA01 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.53 44.0 3.34e-01 91.3% 38.5%
2vsqA04 3.40.50.980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.52 33.0 3.49e-01 77.9% 69.1%
2wqpA01 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.51 46.0 3.84e-01 100.0% 63.5%
1npyA01 3.40.50.10860 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Leucine Dehydrogenase, chain A, domain 1 0.51 33.0 3.82e-01 98.7% 95.0%
2lleA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.51 46.0 3.97e-01 100.0% 88.0%
3ni2A01 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.51 42.0 3.04e-01 89.3% 65.3%
3eucA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.51 43.0 3.88e-01 93.3% 71.0%
ECOD (79)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4343081 2003.1.1.33 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DXP_reductoisom 0.98 96.0 8.54e-01 100.0% 76.4%
4135086 2003.1.1.33 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DXP_reductoisom 0.98 96.0 8.83e-01 100.0% 82.8%
4057998 2003.1.1.33 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DXP_reductoisom 0.98 96.0 8.50e-01 100.0% 84.1%
4396120 2003.1.1.33 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DXP_reductoisom 0.97 95.0 8.96e-01 100.0% 90.6%
4091632 2003.1.1.33 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DXP_reductoisom 0.96 94.0 8.65e-01 100.0% 84.4%
4452496 2003.1.1.33 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DXP_reductoisom 0.96 94.0 8.52e-01 100.0% 80.5%
3972331 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.96 93.0 8.80e-01 99.3% 90.0%
4261607 2003.1.1.33 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DXP_reductoisom 0.95 93.0 8.56e-01 100.0% 82.8%
4865111 2003.1.1.33 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DXP_reductoisom 0.95 84.0 8.63e-01 90.6% 99.3%
4417525 2003.1.1.33 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DXP_reductoisom 0.94 81.0 7.72e-01 100.0% 77.6%
3681218 2003.1.1.33 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DXP_reductoisom 0.94 92.0 8.19e-01 100.0% 88.7%
4464105 2003.1.1.33 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DXP_reductoisom 0.94 76.0 7.93e-01 100.0% 88.6%
4026142 2003.1.1.33 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DXP_reductoisom 0.94 90.0 8.26e-01 100.0% 84.3%
None 0.93 91.0 8.41e-01 100.0% 83.9%
None 0.93 91.0 8.20e-01 100.0% 79.5%
4327067 2003.1.1.33 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DXP_reductoisom 0.93 89.0 8.41e-01 99.3% 85.9%
4056964 2003.1.1.33 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DXP_reductoisom 0.93 89.0 8.30e-01 99.3% 84.0%
4170642 2003.1.1.33 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DXP_reductoisom 0.92 90.0 8.31e-01 100.0% 83.9%
4084494 2003.1.1.33 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DXP_reductoisom 0.92 89.0 8.58e-01 100.0% 91.5%
4410002 2003.1.1.33 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DXP_reductoisom 0.92 90.0 8.48e-01 100.0% 87.6%
4237201 2003.1.1.33 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DXP_reductoisom 0.91 89.0 8.52e-01 100.0% 91.5%
None 0.91 87.0 8.03e-01 98.7% 86.7%
4118896 2003.1.1.33 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DXP_reductoisom 0.91 81.0 8.10e-01 98.7% 90.7%
4117583 2003.1.1.33 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DXP_reductoisom 0.90 79.0 7.92e-01 100.0% 90.0%
4047953 2003.1.1.33 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DXP_reductoisom 0.89 79.0 7.36e-01 98.7% 77.1%
4347920 2003.1.1.33 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DXP_reductoisom 0.89 80.0 7.91e-01 100.0% 89.7%
4107625 2003.1.1.33 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DXP_reductoisom 0.88 78.0 7.82e-01 100.0% 90.7%
4406006 2003.1.1.33 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DXP_reductoisom 0.88 85.0 8.17e-01 100.0% 90.9%
4318536 2003.1.1.33 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DXP_reductoisom 0.87 84.0 8.05e-01 100.0% 91.5%
4093647 2003.1.1.22 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › GFO_IDH_MocA 0.83 69.0 6.00e-01 100.0% 59.5%
None 0.83 63.0 6.33e-01 100.0% 77.3%
None 0.83 69.0 5.98e-01 100.0% 59.5%
2101826 2003.1.1.12 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DapB_N 0.83 57.0 6.69e-01 100.0% 98.1%
3569927 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.74 40.0 3.86e-01 83.2% 46.7%
3600358 323.1.1.0 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.74 48.0 4.01e-01 100.0% 39.6%
5064493 2003.1.1.7 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › ELFV_dehydrog 0.74 64.0 6.06e-01 100.0% 77.5%
5045595 7584.1.1.1 a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › AMP-binding 0.73 43.0 4.10e-01 100.0% 49.7%
3059315 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.72 52.0 5.36e-01 100.0% 78.4%
3285194 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.72 42.0 4.02e-01 100.0% 49.1%
4572461 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.72 44.0 4.01e-01 100.0% 46.2%
5014838 2003.1.1.43 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_3 0.72 67.0 6.15e-01 100.0% 79.3%
5053828 7584.1.1.1 a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › AMP-binding 0.71 44.0 4.36e-01 100.0% 58.1%
4983830 2003.1.1.43 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_3 0.71 67.0 6.12e-01 100.0% 79.5%
5032949 2003.1.1.7 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › ELFV_dehydrog 0.71 67.0 6.22e-01 100.0% 83.3%
3618864 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.71 48.0 4.15e-01 100.0% 45.8%
5065833 2003.1.1.7 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › ELFV_dehydrog 0.70 66.0 6.23e-01 100.0% 85.3%
4988371 2003.1.1.43 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_3 0.70 66.0 6.25e-01 100.0% 85.1%
3725701 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.69 42.0 3.81e-01 100.0% 44.5%
4213191 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.68 44.0 3.91e-01 100.0% 45.7%
4966633 2003.1.1.43 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_3 0.67 63.0 6.17e-01 100.0% 91.9%
3691560 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.67 42.0 3.94e-01 100.0% 50.3%
4421875 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.67 42.0 2.97e-01 100.0% 21.1%
3648473 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.67 41.0 3.91e-01 100.0% 52.0%
4471476 2003.1.1.22 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › GFO_IDH_MocA 0.67 52.0 4.19e-01 83.9% 64.9%
3202057 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.66 36.0 3.34e-01 83.2% 40.0%
5076942 7584.1.1.1 a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › AMP-binding 0.66 42.0 4.14e-01 100.0% 58.7%
3723455 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.66 42.0 3.93e-01 100.0% 52.2%
3939081 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.66 39.0 3.76e-01 98.7% 51.2%
3724541 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.65 43.0 4.04e-01 100.0% 55.0%
4628503 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.63 34.0 3.51e-01 100.0% 52.4%
4360328 323.1.1.0 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.62 35.0 3.31e-01 100.0% 43.2%
1381996 2007.1.3.17 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › AppA_SCHIC 0.60 44.0 4.61e-01 100.0% 83.0%
4990047 7512.1.1.0 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.60 46.0 4.37e-01 81.9% 68.0%
4992673 7597.1.1.1 a/b three-layered sandwiches › Endolysin C-terminal domain › Endolysin C-terminal domain › Endolysin C-terminal domain › CW_binding_2 0.59 37.0 4.26e-01 100.0% 85.5%
3250890 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.59 37.0 3.67e-01 77.2% 58.1%
3700317 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.59 42.0 3.66e-01 91.9% 47.2%
3166357 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.57 40.0 3.83e-01 91.9% 60.6%
3626589 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.56 45.0 4.24e-01 94.6% 70.0%
3786454 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.56 37.0 3.44e-01 90.6% 51.6%
3735229 323.1.1.0 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.56 37.0 3.52e-01 77.2% 55.4%
3735434 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.56 41.0 3.85e-01 94.6% 62.2%
3282865 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.55 38.0 3.49e-01 91.9% 52.2%
4943918 2005.1.1.0 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.55 43.0 4.27e-01 82.6% 81.9%
3695089 323.1.1.0 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.54 38.0 3.71e-01 94.0% 64.7%
3722517 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.53 39.0 3.57e-01 94.6% 57.4%
4343882 2003.6.1.3 a/b three-layered sandwiches › Rossmann-like › Ribokinase-like › Ribokinase-like › HK 0.53 46.0 3.83e-01 95.3% 87.3%
3722431 323.1.1.0 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.52 41.0 3.91e-01 94.6% 70.9%
3645849 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.51 36.0 3.37e-01 77.2% 56.4%
3636565 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.50 33.0 3.08e-01 97.3% 51.1%
D2 high residues 316-396
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF13288.13 best DXPR_C 79.6 3.20e-22 90.1% 62.6%
CATH (40)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3iieB03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.98 94.0 9.28e-01 100.0% 95.3%
4zqeA03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.97 94.0 8.77e-01 100.0% 93.8%
2y1eA03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.97 94.0 9.11e-01 100.0% 95.4%
5jazA03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.96 93.0 8.83e-01 100.0% 94.5%
6mh4A03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.94 84.0 8.54e-01 93.8% 94.9%
3a06B03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.94 91.0 8.77e-01 100.0% 92.0%
5dicA00 1.10.238.20 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain 0.68 45.0 4.00e-01 80.2% 47.8%
2i5uA00 1.10.10.630 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › DnaD domain-like 0.65 54.0 5.53e-01 98.8% 97.4%
1dcnA03 1.10.40.30 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) 0.65 43.0 4.53e-01 79.0% 76.4%
3cxbA03 1.10.1740.30 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Secreted effector protein SifA helical domain 0.65 52.0 5.26e-01 88.9% 87.7%
2mqaA00 1.10.274.60 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain 0.64 48.0 4.27e-01 85.2% 53.6%
2k3oA00 1.10.274.60 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain 0.64 46.0 4.04e-01 88.9% 48.8%
1fc6A01 3.30.750.44 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › 0.64 45.0 4.28e-01 87.7% 61.2%
1zp2A02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.64 47.0 4.28e-01 87.7% 57.1%
3vs8H00 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.64 47.0 3.06e-01 79.0% 49.2%
1yfmA01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.64 49.0 4.34e-01 86.4% 64.3%
7jv7B01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.63 52.0 4.29e-01 91.4% 52.1%
6qumA04 1.10.1140.10 Mainly Alpha › Orthogonal Bundle › Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain; Chain D, domain3 › Bovine Mitochondrial F1-atpase; Atp Synthase Beta Chain; Chain D, domain 3 0.62 53.0 4.40e-01 97.5% 63.1%
3h0dB02 1.10.1200.150 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Transcriptional repressor of class III stress genes, C-terminal domain 0.62 42.0 4.29e-01 77.8% 71.6%
1j8yF01 1.20.120.140 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain 0.61 46.0 4.55e-01 82.7% 76.7%
5xs2B02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.60 48.0 4.12e-01 87.7% 56.8%
2pgsA03 1.10.3410.10 Mainly Alpha › Orthogonal Bundle › putative deoxyguanosinetriphosphate triphosphohydrolase fold › putative deoxyguanosinetriphosphate triphosphohydrolase like domain 0.60 41.0 3.94e-01 72.8% 91.8%
4fzlA01 1.10.150.790 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.59 46.0 4.53e-01 88.9% 78.2%
1or7B01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.59 46.0 4.48e-01 90.1% 75.5%
2h09A02 1.10.60.10 Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › Iron dependent repressor, metal binding and dimerisation domain 0.58 35.0 4.02e-01 79.0% 85.7%
5l3wA01 1.20.120.140 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain 0.57 42.0 4.18e-01 90.1% 76.2%
2bl2A00 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.57 49.0 4.07e-01 100.0% 69.2%
2hs5A02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.56 43.0 3.63e-01 82.7% 63.6%
1tj7A01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.55 43.0 3.98e-01 84.0% 68.6%
1n5uA05 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.55 41.0 3.74e-01 95.1% 58.0%
4m0mA03 1.20.1270.430 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.54 40.0 4.04e-01 79.0% 78.5%
1w36C06 1.10.10.990 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.54 33.0 3.47e-01 77.8% 68.1%
2eucA00 1.10.8.570 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Hypothetical protein YfmB 0.54 39.0 3.57e-01 76.5% 71.0%
3n00A00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.53 43.0 3.39e-01 92.6% 88.0%
1aepA00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.52 38.0 3.18e-01 79.0% 93.5%
2pejA00 1.10.1200.210 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Chaperonin-like RbcX 0.52 36.0 3.31e-01 72.8% 61.5%
2wzkA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.52 44.0 4.00e-01 92.6% 95.5%
3i01A01 1.20.1270.30 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.51 42.0 3.28e-01 90.1% 88.7%
2hg2A01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.51 39.0 2.69e-01 82.7% 63.3%
6ruiB04 3.90.1110.10 Alpha Beta › Alpha-Beta Complex › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3 › RNA polymerase Rpb2, domain 2 0.51 42.0 3.33e-01 95.1% 62.6%
ECOD (66)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4508763 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 1.00 95.0 9.05e-01 97.5% 87.8%
4263712 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.99 94.0 8.77e-01 97.5% 83.2%
4109098 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.99 96.0 8.98e-01 100.0% 86.2%
4201591 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.98 96.0 8.73e-01 100.0% 82.0%
60261 166.1.1.0 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C 0.98 93.0 8.71e-01 98.8% 84.2%
3963621 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.97 94.0 8.62e-01 100.0% 81.8%
3950299 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.97 94.0 8.09e-01 100.0% 75.7%
4048455 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.97 93.0 8.66e-01 98.8% 84.2%
4225289 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.97 94.0 8.07e-01 100.0% 81.7%
4398165 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.97 93.0 8.21e-01 100.0% 73.6%
4224947 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.97 93.0 8.34e-01 100.0% 81.9%
4185708 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.97 89.0 8.37e-01 96.3% 82.1%
1671339 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.96 93.0 8.43e-01 100.0% 84.3%
4682059 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.96 93.0 8.74e-01 100.0% 87.1%
4164998 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.96 91.0 8.36e-01 98.8% 84.0%
4076702 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.96 91.0 8.34e-01 98.8% 82.0%
4096174 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.96 87.0 8.22e-01 95.1% 81.9%
4573573 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.96 92.0 8.80e-01 100.0% 90.0%
4462943 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.95 89.0 8.53e-01 97.5% 91.1%
4144086 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.95 90.0 8.25e-01 98.8% 80.0%
4122932 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.95 90.0 8.59e-01 98.8% 88.9%
2596903 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.94 85.0 8.12e-01 97.5% 83.5%
4478129 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.94 87.0 8.34e-01 96.3% 90.0%
3654522 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.94 91.0 8.15e-01 100.0% 81.9%
4159969 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.94 91.0 8.12e-01 100.0% 82.9%
4080592 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.93 86.0 8.28e-01 97.5% 88.9%
4315742 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.92 86.0 8.09e-01 98.8% 85.3%
4275352 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.92 82.0 7.69e-01 95.1% 80.0%
4118286 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.91 81.0 8.00e-01 96.3% 89.4%
3610347 103.2.1.0 alpha arrays › RuvA-C › ATP cone › ATP cone 0.89 59.0 5.79e-01 79.0% 64.7%
4257656 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.86 76.0 7.34e-01 93.8% 90.0%
4093318 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.86 77.0 7.29e-01 96.3% 82.1%
3207847 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.85 68.0 6.68e-01 84.0% 83.5%
4047291 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.83 74.0 7.20e-01 98.8% 90.0%
3499902 181.1.1.12 alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SCAF11-like_C 0.80 62.0 6.43e-01 87.7% 89.2%
3190824 166.1.1.0 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C 0.79 66.0 6.83e-01 90.1% 98.7%
4017306 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.79 64.0 6.48e-01 87.7% 95.0%
3824733 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.78 64.0 6.31e-01 88.9% 92.9%
3680449 142.1.1.22 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › SCAF11-like_C 0.78 64.0 6.07e-01 88.9% 84.0%
3469007 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.78 63.0 6.28e-01 88.9% 94.1%
5000181 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.77 63.0 5.71e-01 100.0% 65.5%
3242517 4009.1.1.3 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › KTI12 0.76 57.0 5.95e-01 86.4% 85.3%
4397033 103.1.1.6 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › RuvA_C 0.74 51.0 5.75e-01 97.5% 96.6%
4203116 181.1.1.0 alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins 0.73 55.0 5.98e-01 87.7% 100.0%
5070580 181.1.1.0 alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins 0.73 50.0 5.63e-01 80.2% 98.3%
3171507 181.1.1.1 alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N 0.72 54.0 5.47e-01 84.0% 80.0%
3483004 181.1.1.1 alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N 0.72 54.0 5.51e-01 84.0% 81.2%
5003589 181.1.1.0 alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins 0.72 58.0 5.71e-01 87.7% 84.7%
3432597 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.69 49.0 4.51e-01 80.2% 57.1%
3593162 2003.1.5.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.65 53.0 3.42e-01 87.7% 22.6%
4131202 181.1.1.1 alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N 0.64 47.0 4.41e-01 91.4% 63.0%
3990885 164.1.1.0 alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II 0.61 37.0 3.62e-01 100.0% 55.6%
5027801 181.1.1.1 alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N 0.60 46.0 4.30e-01 84.0% 64.8%
5038476 181.1.1.1 alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N 0.60 45.0 4.71e-01 87.7% 94.3%
4931148 2007.1.2.49 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › TfuA 0.59 48.0 3.60e-01 98.8% 34.8%
3237068 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.59 43.0 3.47e-01 75.3% 44.1%
4013358 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.59 48.0 4.34e-01 98.8% 64.5%
3310282 101.1.10.7 alpha arrays › HTH › HTH › Cyclin-like › Cyclin_C 0.58 50.0 4.47e-01 98.8% 97.5%
4993593 198.1.1.27 alpha arrays › Saposin-like › Saposin-like › Saposin-like › PF27234 0.57 42.0 4.26e-01 86.4% 77.5%
55361 4044.1.1.1 alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Prismane 0.54 42.0 3.80e-01 82.7% 62.2%
4948638 601.28.1.0 alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like 0.53 38.0 3.83e-01 75.3% 73.8%
3442186 3755.4.1.17 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Rx_N 0.53 47.0 3.99e-01 97.5% 82.3%
4028015 101.1.17.0 alpha arrays › HTH › HTH › FF domain 0.51 35.0 3.94e-01 85.2% 89.2%
3643152 611.7.1.11 alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › DUF7032 0.50 43.0 3.77e-01 100.0% 84.6%
3251160 5054.1.1.6 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TrkH 0.50 36.0 3.43e-01 77.8% 62.0%
3414776 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.50 37.0 3.10e-01 80.2% 44.1%
D3 medium residues 187-258
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF08436.18 best DXP_redisom_C 88.9 2.70e-25 73.6% 63.1%
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1tk5A04 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.50 36.0 3.30e-01 100.0% 55.6%
ECOD (8)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
None 1.00 97.0 7.60e-01 100.0% 55.4%
3811969 298.1.1.10 a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › DXP_redisom_C 0.98 95.0 7.04e-01 100.0% 46.5%
4666962 298.1.1.0 a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 0.98 94.0 7.78e-01 100.0% 62.6%
None 0.97 94.0 7.39e-01 100.0% 55.4%
None 0.97 91.0 6.89e-01 100.0% 48.3%
None 0.96 92.0 7.27e-01 100.0% 55.4%
None 0.94 90.0 6.74e-01 100.0% 47.1%
3817339 2007.1.19.2 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › FabD/lysophospholipase-like › Patatin 0.51 43.0 2.79e-01 100.0% 95.9%