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CAKLQF020000007.1__CAH1081674.1__SAMEA5780031_01627__00034

Bact-Vir

CAKLQF020000007.1__CAH1081674.1__SAMEA5780031_01627__00034

Identity

Kingdom:
phage

Quality

92.2 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 276-412
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF09611.16 best Cas_Csy1 83.6 2.20e-23 92.7% 33.9%
CATH (29)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5d18A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.63 42.0 3.72e-01 83.2% 45.5%
3a8pA02 6.10.140.680 Special › Helix non-globular › Helix Hairpins › 0.59 41.0 4.49e-01 97.1% 86.0%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.59 44.0 4.70e-01 87.6% 90.6%
3fayA00 1.10.506.10 Mainly Alpha › Orthogonal Bundle › GTPase Activation - p120GAP; domain 1 › GTPase Activation - p120gap; domain 1 0.58 52.0 3.83e-01 100.0% 56.2%
3k66A01 1.20.120.770 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Amyloid precursor protein, E2 domain 0.58 46.0 3.98e-01 97.1% 54.5%
4nn1A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 38.0 3.36e-01 100.0% 44.4%
2pvqA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.57 36.0 3.99e-01 95.6% 79.2%
4hteA03 1.10.167.30 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › 0.57 33.0 4.29e-01 82.5% 100.0%
1fntc01 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.56 42.0 3.80e-01 77.4% 82.4%
1f7uA02 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.55 36.0 3.78e-01 99.3% 71.2%
1n2aA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.55 34.0 3.81e-01 95.6% 79.2%
4g80T00 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.55 40.0 4.01e-01 89.1% 73.4%
7ae2A01 1.20.120.580 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like 0.55 39.0 3.98e-01 99.3% 73.7%
1wrdA00 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 32.0 3.72e-01 80.3% 80.6%
3rv0C02 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.54 39.0 3.93e-01 90.5% 72.2%
2qvaA01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.54 39.0 3.99e-01 100.0% 79.1%
3behB01 1.20.120.540 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels 0.53 37.0 3.94e-01 78.1% 82.9%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.53 37.0 4.08e-01 73.0% 99.1%
1gwcA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.52 38.0 3.82e-01 97.1% 73.8%
5h5mA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.52 40.0 4.16e-01 89.8% 85.4%
3f0cA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 41.0 4.10e-01 100.0% 81.9%
3m0fB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.51 34.0 3.63e-01 95.6% 74.8%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.51 40.0 4.11e-01 94.9% 84.3%
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.51 35.0 3.79e-01 86.9% 81.5%
4fwvA02 1.20.120.1680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.51 37.0 3.78e-01 75.2% 89.6%
3tp3A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.51 41.0 4.07e-01 99.3% 81.8%
2v5cA03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.50 34.0 3.56e-01 97.1% 73.8%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.50 37.0 3.85e-01 90.5% 81.5%
3dcfA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.50 37.0 3.75e-01 100.0% 76.1%
ECOD (31)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4002021 7111.1.1.1 alpha bundles › Ubiquinol-cytochrome C chaperone, C-terminal domain › Ubiquinol-cytochrome C chaperone, C-terminal domain › Ubiquinol-cytochrome C chaperone, C-terminal domain › Ubiq_cyt_C_chap 0.66 46.0 4.28e-01 81.8% 57.1%
3821192 3843.1.1.0 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.65 32.0 4.01e-01 86.9% 76.5%
3740972 109.4.1.821 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › COG3_C 0.64 46.0 3.67e-01 94.9% 36.8%
3933401 3843.1.1.0 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.64 39.0 4.46e-01 88.3% 83.0%
3215718 5069.1.3.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.62 35.0 4.39e-01 95.6% 93.8%
3324184 109.4.1.2 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Arm 0.61 39.0 2.40e-01 94.9% 10.8%
3289317 191.1.1.41 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › EthR_C 0.61 41.0 3.96e-01 83.2% 61.3%
3741819 601.1.2.80 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Yip1 0.61 41.0 4.13e-01 86.9% 68.9%
5074225 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.60 36.0 4.32e-01 89.1% 90.0%
4456477 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.59 45.0 4.18e-01 79.6% 84.0%
3884008 5054.1.1.80 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › PF29331 0.58 40.0 3.89e-01 86.1% 62.6%
3533723 3914.1.1.4 alpha bundles › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › TMC 0.57 51.0 3.45e-01 99.3% 66.4%
5057603 5054.1.1.2 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans 0.57 39.0 3.78e-01 77.4% 62.7%
4945390 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.56 38.0 3.88e-01 97.1% 69.6%
3903804 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.55 41.0 3.73e-01 98.5% 57.8%
3506590 109.4.1.615 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › FANCI_S3,FANCI_S4 0.55 42.0 3.03e-01 95.6% 27.9%
3598036 601.14.1.0 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin 0.55 41.0 4.07e-01 78.1% 84.1%
3629641 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 34.0 2.79e-01 82.5% 34.3%
4446405 1075.5.1.5 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Rft-1 0.54 48.0 3.82e-01 100.0% 69.1%
3640724 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 41.0 3.28e-01 95.6% 41.5%
4117811 316.1.1.2 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 0.53 47.0 4.10e-01 96.4% 70.5%
3233827 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.52 37.0 3.96e-01 86.9% 82.5%
3897905 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.52 39.0 3.43e-01 79.6% 72.1%
None 0.52 47.0 4.18e-01 100.0% 81.0%
3842813 4177.1.1.140 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › DUF4456 0.52 44.0 3.91e-01 91.2% 85.6%
3496091 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.52 39.0 3.99e-01 80.3% 82.2%
3471385 5054.1.1.9 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › PKD_channel 0.51 39.0 2.93e-01 79.6% 45.4%
3529785 601.1.2.6 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_IBS2B 0.51 37.0 3.91e-01 90.5% 84.0%
5044690 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.50 44.0 3.87e-01 100.0% 86.4%
3878141 601.1.1.7 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B 0.50 37.0 3.87e-01 90.5% 84.0%
3529790 601.1.1.57 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_VBS2 0.50 38.0 3.89e-01 93.4% 83.1%
D2 medium residues 1-61_97-155
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF09611.16 best Cas_Csy1 40.4 2.80e-10 51.7% 15.6%
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2gslF00 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.64 44.0 4.40e-01 96.7% 66.9%
1jfzA00 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.59 36.0 3.38e-01 89.2% 47.3%
3rv0C02 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.58 37.0 3.51e-01 93.3% 53.5%
3triA02 1.10.3730.10 Mainly Alpha › Orthogonal Bundle › ProC C-terminal domain-like fold › ProC C-terminal domain-like 0.56 38.0 4.08e-01 70.0% 90.3%
4gf0A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.52 35.0 3.58e-01 88.3% 71.7%
ECOD (16)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3858695 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.68 37.0 4.37e-01 99.2% 75.3%
3347379 3470.1.1.26 extended segments › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain › DUF543 0.67 33.0 4.39e-01 92.5% 87.7%
3764064 4009.1.1.0 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.66 37.0 4.35e-01 99.2% 78.8%
3643105 6026.1.1.1 alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain › cwf21 0.63 43.0 4.01e-01 78.3% 54.2%
4501780 310.2.1.5 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › DUF842 0.62 34.0 3.35e-01 80.0% 49.6%
3882597 4009.1.1.0 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.61 34.0 3.89e-01 72.5% 72.2%
3988447 5043.1.1.0 extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like 0.61 29.0 3.83e-01 90.8% 92.7%
3962550 5067.1.1.0 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain 0.61 46.0 3.86e-01 79.2% 84.5%
4003423 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.60 29.0 2.83e-01 96.7% 38.6%
3659606 3361.1.1.5 alpha bundles › C-terminal Pdr1-activating domain of J-protein Zuo1 › C-terminal Pdr1-activating domain of J-protein Zuo1 › C-terminal Pdr1-activating domain of J-protein Zuo1 › PF28983 0.59 31.0 3.18e-01 95.0% 51.3%
3299872 5063.1.1.3 alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › NADH-u_ox-rdase 0.54 31.0 3.56e-01 81.7% 77.6%
4998875 141.1.1.1 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › polyprenyl_synt 0.53 42.0 3.10e-01 87.5% 37.3%
3449004 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.51 36.0 3.22e-01 99.2% 52.1%
3612308 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.51 37.0 3.88e-01 77.5% 92.0%
3584845 150.1.1.80 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Myelin_PLP 0.51 38.0 3.35e-01 78.3% 84.4%
4026102 592.1.1.1 alpha arrays › PWI domain-like › PWI domain › PWI domain › PWI 0.50 30.0 3.56e-01 78.3% 93.3%
D3 medium residues 62-96_161-192
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF09611.16 best Cas_Csy1 35.9 6.90e-09 52.2% 8.7%
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1yfbA00 2.10.260.10 Mainly Beta › Ribbon › Pemi-like Protein 1; Chain: D › 0.57 28.0 3.12e-01 74.6% 53.8%
2rblA01 2.20.25.10 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › 0.52 24.0 3.03e-01 79.1% 85.7%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5050197 1.1.3.2 beta barrels › cradle loop barrel › RIFT-related › AbrB › MazE_antitoxin 0.63 34.0 3.30e-01 79.1% 45.3%
3886839 391.1.1.1 few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › Fibronectin type I module › fn1 0.60 26.0 3.22e-01 88.1% 57.5%
4965853 1.1.3.9 beta barrels › cradle loop barrel › RIFT-related › AbrB › PF26227 0.55 31.0 3.16e-01 77.6% 55.4%
3738506 4325.1.1.4 mixed a+b and a/b › YegP-like › YegP-like › YegP-like › DIPSY 0.55 25.0 3.10e-01 91.0% 62.5%
3590853 1.1.3.0 beta barrels › cradle loop barrel › RIFT-related › AbrB 0.54 30.0 3.26e-01 83.6% 61.8%
4792723 3223.1.1.1 beta sandwiches › Amiloride-sensitive cation channel 2 › Amiloride-sensitive cation channel 2 › Amiloride-sensitive cation channel 2 › ASC 0.53 28.0 2.83e-01 91.0% 47.1%
D4 medium residues 193-256
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF09611.16 best Cas_Csy1 84.6 1.00e-23 100.0% 16.7%
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2704926 3576.2.1.1 a+b complex topology › Cas8-like › Cas8f/Csy1 › Cas8f/Csy1 › Cas_Csy1 0.91 84.0 4.96e-01 100.0% 15.0%
2324061 3576.2.1.0 a+b complex topology › Cas8-like › Cas8f/Csy1 › Cas8f/Csy1 0.88 81.0 4.78e-01 100.0% 15.1%