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CAKLQF020000007.1__CAH1081678.1__SAMEA5780031_01631__00038
Bact-VirCAKLQF020000007.1__CAH1081678.1__SAMEA5780031_01631__00038
Identity
- Kingdom:
- phage
Quality
93.2
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-35_121-205
Domain cluster:
rep: DQ372923.1__ABD94166.1__X__00001__D3-29_112-184
CATH (30)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2cveA02 | 3.30.70.240 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.68 | 38.0 | 4.93e-01 | 84.2% | 100.0% |
| 1srqA01 | 3.30.1120.160 | Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › | 0.67 | 44.0 | 4.18e-01 | 80.8% | 57.2% |
| 2fpnA01 | 3.30.2030.10 | Alpha Beta › 2-Layer Sandwich › TBP-like › YwmB-like | 0.64 | 51.0 | 4.91e-01 | 86.7% | 78.6% |
| 1kyfA02 | 3.30.310.10 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › TATA-Binding Protein | 0.63 | 48.0 | 4.97e-01 | 80.8% | 85.8% |
| 6ka3A01 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.63 | 48.0 | 4.54e-01 | 81.7% | 97.3% |
| 5e4bA00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.62 | 50.0 | 4.43e-01 | 86.7% | 96.0% |
| 3q63F00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.62 | 48.0 | 4.60e-01 | 82.5% | 95.0% |
| 2pwwA00 | 3.30.310.100 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › YugN-like | 0.61 | 47.0 | 4.77e-01 | 80.8% | 97.4% |
| 5i8fA00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.61 | 47.0 | 4.28e-01 | 82.5% | 87.2% |
| 1fm4A00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.60 | 47.0 | 4.28e-01 | 82.5% | 91.8% |
| 2ns9A01 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.59 | 46.0 | 4.29e-01 | 81.7% | 95.3% |
| 2wqlA00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.59 | 45.0 | 4.18e-01 | 81.7% | 96.7% |
| 1z94B00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.58 | 44.0 | 4.23e-01 | 81.7% | 94.4% |
| 4h5bA00 | 3.30.1460.70 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.57 | 42.0 | 3.87e-01 | 75.0% | 80.3% |
| 2cztA00 | 2.40.128.20 | Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain | 0.56 | 46.0 | 4.21e-01 | 86.7% | 87.1% |
| 2ynkA00 | 2.40.160.130 | Mainly Beta › Beta Barrel › Porin › Capsule assembly protein Wzi | 0.53 | 44.0 | 3.11e-01 | 95.0% | 71.7% |
| 3vskA03 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.53 | 45.0 | 3.20e-01 | 92.5% | 95.0% |
| 1m6kA00 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.53 | 46.0 | 3.56e-01 | 93.3% | 96.4% |
| 7rd0A02 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.53 | 44.0 | 3.28e-01 | 92.5% | 96.0% |
| 1hq0A00 | 3.60.100.10 | Alpha Beta › 4-Layer Sandwich › Cytotoxic necrotizing factor 1 (CNF1) › Cytotoxic necrotizing factor, Rho-activating domain | 0.52 | 42.0 | 3.24e-01 | 88.3% | 86.4% |
| 3bnvD00 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.52 | 40.0 | 3.75e-01 | 79.2% | 90.2% |
| 6f1uK02 | 3.90.1150.210 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › F-actin capping protein, beta subunit | 0.52 | 39.0 | 3.69e-01 | 78.3% | 89.0% |
| 1h7zA00 | 2.60.90.10 | Mainly Beta › Sandwich › Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) › Adenovirus pIV-related, attachment domain | 0.52 | 38.0 | 3.28e-01 | 76.7% | 64.9% |
| 3kg7B00 | 3.10.129.110 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Polyketide synthase dehydratase | 0.52 | 38.0 | 2.88e-01 | 75.8% | 50.9% |
| 1ln1A00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.52 | 43.0 | 3.62e-01 | 90.0% | 96.6% |
| 3hlzB01 | 3.40.1000.10 | Alpha Beta › 3-Layer(aba) Sandwich › Protein Transport Mog1p; Chain A › Mog1/PsbP, alpha/beta/alpha sandwich | 0.51 | 46.0 | 4.40e-01 | 97.5% | 87.1% |
| 4fnvA02 | 2.70.98.70 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › | 0.51 | 42.0 | 3.26e-01 | 90.0% | 79.8% |
| 1pn2B01 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.51 | 35.0 | 3.31e-01 | 84.2% | 57.4% |
| 3ub1D02 | 3.10.450.540 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.51 | 35.0 | 3.58e-01 | 70.0% | 97.4% |
| 5o16B00 | 3.10.129.110 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Polyketide synthase dehydratase | 0.50 | 38.0 | 2.95e-01 | 80.8% | 49.6% |
ECOD (48)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3972144 | 868.1.1.1 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › CYTH | 0.94 | 87.0 | 7.01e-01 | 95.8% | 99.5% |
| 3513698 | 868.1.1.1 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › CYTH | 0.93 | 89.0 | 7.22e-01 | 99.2% | 99.5% |
| 5002666 | 868.1.1.1 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › CYTH | 0.91 | 81.0 | 6.60e-01 | 92.5% | 100.0% |
| 3253396 | 868.1.1.2 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA_triPase | 0.87 | 67.0 | 5.48e-01 | 80.0% | 89.8% |
| 3677170 | 868.1.1.11 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › DUF7903 | 0.78 | 61.0 | 4.57e-01 | 81.7% | 89.6% |
| 3722183 | 868.1.1.0 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related | 0.76 | 68.0 | 5.20e-01 | 96.7% | 99.6% |
| 3291496 | 868.1.1.0 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related | 0.75 | 67.0 | 5.17e-01 | 95.0% | 99.6% |
| 5037261 | 331.4.1.0 ↗ | a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 | 0.73 | 57.0 | 5.25e-01 | 82.5% | 78.7% |
| 3474976 | 331.9.1.0 ↗ | a+b two layers › TBP-like › Subdomain of clathrin and coatomer appendage domain › Subdomain of clathrin and coatomer appendage domain | 0.70 | 55.0 | 5.34e-01 | 82.5% | 87.7% |
| 3725715 | 331.4.1.4 ↗ | a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 › Fungal_KA1 | 0.67 | 57.0 | 5.46e-01 | 92.5% | 95.7% |
| 4026900 | 331.9.1.0 ↗ | a+b two layers › TBP-like › Subdomain of clathrin and coatomer appendage domain › Subdomain of clathrin and coatomer appendage domain | 0.66 | 51.0 | 5.26e-01 | 84.2% | 84.3% |
| 6336 | 331.13.1.1 ↗ | a+b two layers › TBP-like › YwmB-like › YwmB-like › DUF1779 | 0.65 | 52.0 | 4.36e-01 | 85.0% | 53.7% |
| 3614126 | 868.1.1.0 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related | 0.65 | 50.0 | 4.24e-01 | 82.5% | 87.3% |
| 5044863 | 331.9.1.0 ↗ | a+b two layers › TBP-like › Subdomain of clathrin and coatomer appendage domain › Subdomain of clathrin and coatomer appendage domain | 0.64 | 51.0 | 5.00e-01 | 85.0% | 86.9% |
| 3784816 | 331.9.1.1 ↗ | a+b two layers › TBP-like › Subdomain of clathrin and coatomer appendage domain › Subdomain of clathrin and coatomer appendage domain › Alpha_adaptin_C | 0.64 | 50.0 | 4.95e-01 | 82.5% | 83.2% |
| 5038083 | 331.9.1.0 ↗ | a+b two layers › TBP-like › Subdomain of clathrin and coatomer appendage domain › Subdomain of clathrin and coatomer appendage domain | 0.64 | 49.0 | 4.93e-01 | 82.5% | 80.6% |
| 3281686 | 331.3.1.27 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › DUF2505 | 0.63 | 49.0 | 4.38e-01 | 81.7% | 93.9% |
| 4997740 | 331.9.1.0 ↗ | a+b two layers › TBP-like › Subdomain of clathrin and coatomer appendage domain › Subdomain of clathrin and coatomer appendage domain | 0.63 | 49.0 | 4.66e-01 | 82.5% | 80.7% |
| 5047424 | 331.9.1.0 ↗ | a+b two layers › TBP-like › Subdomain of clathrin and coatomer appendage domain › Subdomain of clathrin and coatomer appendage domain | 0.63 | 48.0 | 4.88e-01 | 81.7% | 85.8% |
| 3711119 | 331.9.1.0 ↗ | a+b two layers › TBP-like › Subdomain of clathrin and coatomer appendage domain › Subdomain of clathrin and coatomer appendage domain | 0.63 | 47.0 | 4.83e-01 | 80.8% | 82.6% |
| 5047426 | 331.9.1.0 ↗ | a+b two layers › TBP-like › Subdomain of clathrin and coatomer appendage domain › Subdomain of clathrin and coatomer appendage domain | 0.62 | 48.0 | 4.89e-01 | 80.8% | 88.7% |
| 4970968 | 331.10.2.0 ↗ | a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › Bacterial S-adenosylmethionine decarboxylase | 0.62 | 48.0 | 4.96e-01 | 80.8% | 93.8% |
| 3993872 | 331.3.1.0 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like | 0.62 | 48.0 | 4.09e-01 | 81.7% | 75.3% |
| 3707067 | 331.3.1.0 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like | 0.62 | 55.0 | 4.46e-01 | 97.5% | 83.1% |
| 5047928 | 331.9.1.0 ↗ | a+b two layers › TBP-like › Subdomain of clathrin and coatomer appendage domain › Subdomain of clathrin and coatomer appendage domain | 0.62 | 48.0 | 4.85e-01 | 82.5% | 86.7% |
| 5047469 | 331.10.2.0 ↗ | a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › Bacterial S-adenosylmethionine decarboxylase | 0.62 | 49.0 | 4.86e-01 | 86.7% | 96.9% |
| 3897847 | 216.1.1.2 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like › Autophagy_act_C | 0.61 | 43.0 | 3.88e-01 | 72.5% | 57.4% |
| 3230598 | 216.1.1.0 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like | 0.61 | 44.0 | 4.10e-01 | 75.0% | 60.7% |
| 4445572 | 4099.1.1.22 ↗ | a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › CENP-P | 0.60 | 42.0 | 4.12e-01 | 70.8% | 85.4% |
| 5005014 | 881.1.1.0 ↗ | a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like | 0.60 | 45.0 | 3.61e-01 | 78.3% | 78.7% |
| 6333 | 331.3.1.7 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › COXG | 0.59 | 46.0 | 4.30e-01 | 81.7% | 95.9% |
| 3175088 | 331.3.1.5 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Polyketide_cyc | 0.59 | 45.0 | 4.10e-01 | 81.7% | 86.7% |
| 3280926 | 881.1.1.6 ↗ | a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like › Lpp-LpqN | 0.59 | 41.0 | 3.63e-01 | 71.7% | 81.0% |
| 5010189 | 331.3.1.0 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like | 0.59 | 45.0 | 4.32e-01 | 81.7% | 92.8% |
| 3939338 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.58 | 40.0 | 3.41e-01 | 70.0% | 93.3% |
| 3258216 | 12.3.1.46 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › ComC_SSD | 0.58 | 43.0 | 3.54e-01 | 78.3% | 90.7% |
| 3794870 | 216.1.1.2 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like › Autophagy_act_C | 0.58 | 45.0 | 4.09e-01 | 81.7% | 71.2% |
| 3838939 | 5084.5.1.0 ↗ | beta barrels › Outer membrane meander beta-barrels › Porins › Porin | 0.56 | 43.0 | 2.99e-01 | 80.0% | 81.5% |
| 4254174 | 4099.1.1.22 ↗ | a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › CENP-P | 0.56 | 39.0 | 3.72e-01 | 71.7% | 71.0% |
| 3283330 | 331.3.1.20 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › KshA_C | 0.56 | 43.0 | 3.40e-01 | 81.7% | 60.0% |
| 5037445 | 2003.1.5.81 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 | 0.53 | 37.0 | 2.85e-01 | 71.7% | 75.0% |
| 5034702 | 881.1.1.0 ↗ | a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like | 0.52 | 44.0 | 4.11e-01 | 89.2% | 85.9% |
| 3228525 | 241.15.1.0 ↗ | a+b two layers › Type III secretory system chaperone-like › FP (Fbxo7/PI31) dimerization domain › FP (Fbxo7/PI31) dimerization domain | 0.52 | 37.0 | 3.92e-01 | 75.0% | 90.9% |
| 4941093 | 881.1.1.0 ↗ | a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like | 0.52 | 44.0 | 4.11e-01 | 91.7% | 89.3% |
| 4675848 | 9.2.1.1 ↗ | beta barrels › Lipocalins/Streptavidin › Avidin/Streptavidin › Avidin/Streptavidin › Avidin | 0.51 | 39.0 | 3.71e-01 | 79.2% | 79.1% |
| 3962319 | 881.1.1.0 ↗ | a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like | 0.51 | 42.0 | 3.94e-01 | 89.2% | 78.0% |
| 2123690 | 881.1.1.9 ↗ | a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like › Tli4_C | 0.51 | 44.0 | 4.04e-01 | 95.8% | 79.1% |
| 1286181 | 881.1.1.7 ↗ | a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like › DUF3805 | 0.50 | 45.0 | 4.34e-01 | 96.7% | 86.8% |
D2
medium
residues 36-120
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01928.27 best | CYTH | 31.9 | 1.70e-07 | 94.1% | 24.6% |
CATH (24)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2acaA00 | 2.40.320.10 | Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 | 0.79 | 57.0 | 4.35e-01 | 100.0% | 36.2% |
| 2gfgA00 | 2.40.320.10 | Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 | 0.77 | 69.0 | 5.18e-01 | 100.0% | 42.4% |
| 1hkgA02 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.64 | 50.0 | 4.42e-01 | 87.1% | 96.2% |
| 4z9cB00 | 2.40.50.110 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › | 0.62 | 43.0 | 3.84e-01 | 75.3% | 52.2% |
| 7oufB01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.62 | 50.0 | 4.11e-01 | 87.1% | 61.1% |
| 3zs7A00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.59 | 44.0 | 3.15e-01 | 81.2% | 43.7% |
| 4l8hB00 | 3.30.380.10 | Alpha Beta › 2-Layer Sandwich › MS2 Viral Coat Protein › MS2 Viral Coat Protein | 0.59 | 44.0 | 3.88e-01 | 78.8% | 87.0% |
| 4htgA03 | 3.30.160.40 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain | 0.58 | 43.0 | 4.47e-01 | 80.0% | 87.3% |
| 1bf5A04 | 3.30.505.10 | Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain | 0.57 | 44.0 | 4.09e-01 | 85.9% | 75.2% |
| 1ah5A03 | 3.30.160.40 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain | 0.56 | 44.0 | 4.41e-01 | 85.9% | 87.2% |
| 3ecrB03 | 3.30.160.40 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain | 0.56 | 44.0 | 4.18e-01 | 85.9% | 88.2% |
| 3zt9A00 | 3.60.40.10 | Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain | 0.55 | 47.0 | 3.71e-01 | 97.6% | 96.4% |
| 3ke6B01 | 3.60.40.10 | Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain | 0.55 | 47.0 | 3.57e-01 | 97.6% | 97.3% |
| 2xepB02 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.55 | 41.0 | 2.96e-01 | 80.0% | 29.7% |
| 2giaB00 | 2.30.31.40 | Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › | 0.55 | 48.0 | 4.05e-01 | 100.0% | 83.6% |
| 1a1xA00 | 2.40.15.10 | Mainly Beta › Beta Barrel › Proto-oncogene - Oncogene Product P14tcl1 › TCL1/MTCP1 | 0.54 | 30.0 | 2.81e-01 | 100.0% | 39.6% |
| 2zf3C00 | 2.50.20.30 | Mainly Beta › Clam › outer membrane lipoprotein receptor (LolB), chain A › | 0.53 | 40.0 | 3.12e-01 | 80.0% | 92.3% |
| 2vsmA00 | 2.120.10.10 | Mainly Beta › 6 Propeller › Neuraminidase › | 0.52 | 45.0 | 2.96e-01 | 100.0% | 90.3% |
| 3b5hA01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.52 | 41.0 | 4.15e-01 | 84.7% | 95.1% |
| 1whqA01 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.52 | 38.0 | 4.06e-01 | 80.0% | 98.6% |
| 3wasA00 | 2.115.10.20 | Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 | 0.51 | 42.0 | 2.79e-01 | 94.1% | 70.7% |
| 3a7rA02 | 3.30.390.50 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › CO dehydrogenase flavoprotein, C-terminal domain | 0.51 | 42.0 | 4.24e-01 | 97.6% | 92.1% |
| 4ikcA00 | 3.90.190.10 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily | 0.50 | 35.0 | 2.55e-01 | 74.1% | 53.3% |
| 1t17A00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.50 | 41.0 | 3.56e-01 | 95.3% | 79.7% |
ECOD (63)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3972144 | 868.1.1.1 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › CYTH | 0.84 | 75.0 | 5.49e-01 | 100.0% | 39.0% |
| 3513698 | 868.1.1.1 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › CYTH | 0.81 | 73.0 | 5.35e-01 | 100.0% | 39.5% |
| 3588533 | 868.1.1.1 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › CYTH | 0.79 | 71.0 | 5.35e-01 | 100.0% | 43.2% |
| 3987480 | 868.1.1.1 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › CYTH | 0.78 | 70.0 | 5.30e-01 | 100.0% | 43.8% |
| 160441 | 868.1.1.1 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › CYTH | 0.77 | 69.0 | 5.18e-01 | 100.0% | 42.4% |
| 4033840 | 868.1.1.1 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › CYTH | 0.76 | 69.0 | 5.16e-01 | 100.0% | 43.2% |
| 4985112 | 868.1.1.1 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › CYTH | 0.73 | 57.0 | 4.36e-01 | 100.0% | 38.3% |
| 3695594 | 2484.1.1.176 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hexokinase_1+Hexokinase_2 | 0.71 | 58.0 | 3.56e-01 | 88.2% | 27.4% |
| 5002666 | 868.1.1.1 ↗ | a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › CYTH | 0.70 | 60.0 | 4.57e-01 | 100.0% | 40.5% |
| 4096100 | 2484.1.1.176 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hexokinase_1+Hexokinase_2 | 0.66 | 54.0 | 3.33e-01 | 88.2% | 26.5% |
| 3734443 | 2484.1.1.5 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hexokinase_1 | 0.66 | 54.0 | 3.95e-01 | 88.2% | 57.8% |
| 3507037 | 2484.1.1.176 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hexokinase_1+Hexokinase_2 | 0.64 | 52.0 | 3.25e-01 | 88.2% | 27.5% |
| 3416070 | 5.1.4.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed | 0.63 | 43.0 | 2.83e-01 | 70.6% | 69.3% |
| 3482455 | 10.1.1.17 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Laminin_G_2 | 0.62 | 54.0 | 4.16e-01 | 100.0% | 85.2% |
| 5005723 | 223.1.1.14 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_4 | 0.61 | 47.0 | 3.30e-01 | 82.4% | 67.5% |
| 3924626 | 2484.1.1.4 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H | 0.61 | 46.0 | 4.69e-01 | 82.4% | 91.8% |
| 3393619 | 284.4.1.2 ↗ | a+b two layers › FKBP-like › Archaeal FKBP insertion domain › Archaeal FKBP insertion domain › PF28923 | 0.60 | 36.0 | 4.39e-01 | 88.2% | 100.0% |
| 3601539 | 2484.1.1.26 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Piwi | 0.59 | 49.0 | 3.63e-01 | 91.8% | 46.5% |
| 4161565 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.59 | 47.0 | 4.59e-01 | 88.2% | 93.7% |
| 4058654 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.58 | 46.0 | 4.42e-01 | 87.1% | 77.8% |
| 3605420 | 2484.1.1.26 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Piwi | 0.58 | 46.0 | 3.39e-01 | 89.4% | 42.0% |
| 4975692 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.58 | 46.0 | 4.56e-01 | 88.2% | 86.7% |
| 4048220 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.58 | 46.0 | 4.76e-01 | 88.2% | 97.5% |
| 4558929 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.58 | 43.0 | 4.45e-01 | 81.2% | 87.5% |
| 3794870 | 216.1.1.2 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like › Autophagy_act_C | 0.58 | 48.0 | 3.90e-01 | 91.8% | 90.0% |
| 4609498 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.57 | 46.0 | 4.77e-01 | 90.6% | 98.8% |
| 4025734 | 2006.1.6.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like | 0.57 | 51.0 | 3.76e-01 | 100.0% | 87.1% |
| 4132764 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.56 | 44.0 | 4.41e-01 | 85.9% | 88.2% |
| 4964031 | 7089.1.1.7 ↗ | a+b two layers › Methane monooxygenase hydroxylase, MmoD › Methane monooxygenase hydroxylase, MmoD › Methane monooxygenase hydroxylase, MmoD › DUF7543 | 0.56 | 42.0 | 4.62e-01 | 81.2% | 97.1% |
| 4336488 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.56 | 41.0 | 4.37e-01 | 81.2% | 92.9% |
| 3618372 | 2484.1.1.99 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Peptidase_A17 | 0.56 | 46.0 | 4.14e-01 | 90.6% | 87.5% |
| 2698437 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.56 | 44.0 | 3.78e-01 | 87.1% | 73.6% |
| 4935472 | 330.4.1.0 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain | 0.56 | 42.0 | 4.57e-01 | 83.5% | 100.0% |
| 3839010 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.56 | 44.0 | 4.41e-01 | 87.1% | 87.1% |
| 3675483 | 5.1.4.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed | 0.56 | 40.0 | 2.63e-01 | 76.5% | 38.7% |
| 4961150 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.55 | 43.0 | 4.19e-01 | 85.9% | 80.6% |
| 4262169 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.55 | 43.0 | 4.24e-01 | 87.1% | 84.9% |
| 4365325 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.55 | 43.0 | 4.34e-01 | 85.9% | 85.9% |
| 4638542 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.55 | 45.0 | 4.43e-01 | 94.1% | 90.5% |
| 3832419 | 319.1.1.13 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › PF26144 | 0.55 | 37.0 | 3.59e-01 | 70.6% | 61.0% |
| 4036906 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.55 | 42.0 | 4.36e-01 | 85.9% | 91.3% |
| 4157358 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.55 | 42.0 | 4.32e-01 | 84.7% | 91.0% |
| 3937910 | 319.1.1.1 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 | 0.55 | 37.0 | 3.70e-01 | 87.1% | 69.4% |
| 3897847 | 216.1.1.2 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like › Autophagy_act_C | 0.54 | 46.0 | 3.70e-01 | 94.1% | 90.5% |
| 4460237 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.54 | 40.0 | 4.17e-01 | 81.2% | 89.3% |
| 4187672 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.54 | 41.0 | 4.33e-01 | 84.7% | 97.3% |
| 3479176 | 319.1.1.0 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones | 0.54 | 35.0 | 3.62e-01 | 84.7% | 70.0% |
| 3498230 | 319.1.1.1 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 | 0.54 | 35.0 | 3.61e-01 | 84.7% | 70.0% |
| 4965501 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.54 | 42.0 | 4.14e-01 | 88.2% | 86.7% |
| 3279407 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.53 | 38.0 | 3.51e-01 | 74.1% | 71.8% |
| 3223921 | 2484.1.1.259 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF26742 | 0.53 | 44.0 | 4.33e-01 | 91.8% | 87.8% |
| 4438684 | 330.4.1.1 ↗ | a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC | 0.53 | 40.0 | 4.06e-01 | 84.7% | 84.5% |
| 3282063 | 331.3.1.11 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Polyketide_cyc2 | 0.53 | 44.0 | 4.01e-01 | 97.6% | 93.6% |
| 3789856 | 330.1.1.1 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm | 0.53 | 43.0 | 3.91e-01 | 89.4% | 71.3% |
| 3265841 | 216.1.1.20 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like › UBC_like | 0.53 | 41.0 | 3.94e-01 | 84.7% | 98.0% |
| 3670595 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.53 | 40.0 | 3.96e-01 | 89.4% | 76.8% |
| 4056691 | 319.1.1.0 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones | 0.52 | 35.0 | 3.17e-01 | 88.2% | 50.0% |
| 3608102 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.52 | 39.0 | 4.14e-01 | 91.8% | 100.0% |
| 3490957 | 319.1.1.1 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 | 0.52 | 34.0 | 3.54e-01 | 72.9% | 74.7% |
| 3722420 | 2008.1.1.143 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF7924 | 0.51 | 41.0 | 3.39e-01 | 88.2% | 63.7% |
| 4026006 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.51 | 38.0 | 3.95e-01 | 83.5% | 87.5% |
| 3243813 | 11.10.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › TRAF domain-like › TRAF domain-like | 0.51 | 38.0 | 3.46e-01 | 81.2% | 84.2% |
| 3430171 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.50 | 39.0 | 2.51e-01 | 84.7% | 21.1% |
D3
medium
residues 206-360
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05235.20 best | CHAD | 56.0 | 8.30e-15 | 84.5% | 38.6% |
CATH (35)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3e0sA00 | 1.40.20.10 | Mainly Alpha › Alpha solenoid › CHAD domain › CHAD domain | 0.86 | 79.0 | 6.17e-01 | 95.5% | 56.1% |
| 1tqgA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.79 | 53.0 | 6.35e-01 | 89.0% | 100.0% |
| 3kyiA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.76 | 51.0 | 5.56e-01 | 89.0% | 82.0% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.73 | 50.0 | 5.75e-01 | 88.4% | 95.6% |
| 3zsuA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.72 | 50.0 | 5.68e-01 | 88.4% | 93.2% |
| 3thxA03 | 1.10.1420.10 | Mainly Alpha › Orthogonal Bundle › MutS, DNA mismatch repair protein; Chain A, domain 3 › | 0.71 | 60.0 | 5.20e-01 | 87.7% | 71.9% |
| 1orjD00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.71 | 50.0 | 5.52e-01 | 90.3% | 88.8% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.70 | 55.0 | 5.81e-01 | 91.0% | 92.0% |
| 2yfaB01 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.69 | 51.0 | 5.78e-01 | 87.7% | 100.0% |
| 2hz8A00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.69 | 50.0 | 5.64e-01 | 86.5% | 99.1% |
| 1m56C02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.68 | 57.0 | 5.22e-01 | 87.7% | 71.4% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.68 | 54.0 | 5.85e-01 | 92.3% | 100.0% |
| 1e3mB04 | 1.10.1420.10 | Mainly Alpha › Orthogonal Bundle › MutS, DNA mismatch repair protein; Chain A, domain 3 › | 0.65 | 53.0 | 5.41e-01 | 90.3% | 89.5% |
| 3pwxA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.65 | 52.0 | 4.87e-01 | 90.3% | 70.7% |
| 3thxB03 | 1.10.1420.10 | Mainly Alpha › Orthogonal Bundle › MutS, DNA mismatch repair protein; Chain A, domain 3 › | 0.64 | 46.0 | 4.35e-01 | 85.2% | 62.0% |
| 5u1aL00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.63 | 46.0 | 4.54e-01 | 75.5% | 99.4% |
| 1fntc01 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.62 | 53.0 | 5.01e-01 | 91.6% | 91.5% |
| 4r42A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.62 | 43.0 | 4.04e-01 | 70.3% | 89.3% |
| 1bbhA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.61 | 48.0 | 5.23e-01 | 88.4% | 97.7% |
| 8hixR01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.61 | 46.0 | 3.77e-01 | 77.4% | 84.7% |
| 4cbeA00 | 1.20.120.1640 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.60 | 51.0 | 4.63e-01 | 91.0% | 75.6% |
| 1q16C01 | 1.20.950.20 | Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C | 0.58 | 45.0 | 4.11e-01 | 83.2% | 78.0% |
| 1avoB00 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.58 | 41.0 | 4.29e-01 | 71.6% | 91.4% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.57 | 45.0 | 4.87e-01 | 88.4% | 100.0% |
| 1b68A00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.56 | 47.0 | 4.94e-01 | 89.7% | 100.0% |
| 5j1hA01 | 1.20.58.1060 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 40.0 | 3.84e-01 | 74.2% | 80.8% |
| 2ap3A00 | 1.20.120.570 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YkyA-like | 0.56 | 46.0 | 4.31e-01 | 88.4% | 85.4% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 31.0 | 3.65e-01 | 92.3% | 78.5% |
| 2y1vA04 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.54 | 36.0 | 3.39e-01 | 76.8% | 56.2% |
| 1dn1B00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 38.0 | 3.36e-01 | 73.5% | 82.4% |
| 3c1yA02 | 1.20.1260.110 | Mainly Alpha › Up-down Bundle › Ferritin › DNA integrity scanning linker region | 0.52 | 43.0 | 4.43e-01 | 99.4% | 91.2% |
| 1to9A00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.52 | 42.0 | 3.70e-01 | 84.5% | 80.0% |
| 1r0dA00 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.52 | 36.0 | 3.38e-01 | 70.3% | 56.0% |
| 2lquA01 | 1.20.1420.40 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Decorin-binding protein | 0.52 | 45.0 | 4.61e-01 | 97.4% | 95.5% |
| 2dnxA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.50 | 36.0 | 3.88e-01 | 72.9% | 94.6% |
ECOD (52)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4949044 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.82 | 52.0 | 6.06e-01 | 85.8% | 87.6% |
| 3967072 | 601.3.1.26 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › PF26379 | 0.81 | 50.0 | 4.86e-01 | 83.9% | 56.5% |
| 3967073 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.79 | 53.0 | 5.98e-01 | 89.0% | 87.5% |
| 3974600 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.77 | 51.0 | 5.60e-01 | 87.7% | 80.0% |
| 5083304 | 601.33.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD | 0.77 | 61.0 | 6.51e-01 | 81.9% | 100.0% |
| 3971690 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.77 | 53.0 | 5.86e-01 | 89.0% | 87.2% |
| 5081366 | 601.33.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain | 0.76 | 63.0 | 6.23e-01 | 87.7% | 93.9% |
| 4935669 | 601.33.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD | 0.73 | 59.0 | 6.24e-01 | 85.2% | 94.3% |
| 3974204 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.70 | 52.0 | 5.87e-01 | 90.3% | 100.0% |
| 3540099 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.68 | 58.0 | 5.49e-01 | 89.0% | 100.0% |
| 4020563 | 601.16.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › GIT1_C | 0.68 | 53.0 | 5.69e-01 | 89.0% | 96.9% |
| 4011946 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.68 | 56.0 | 5.94e-01 | 87.7% | 100.0% |
| 3217635 | 3684.1.1.30 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PF29678 | 0.68 | 57.0 | 5.56e-01 | 92.9% | 81.8% |
| 3599103 | 601.23.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_III | 0.67 | 56.0 | 4.36e-01 | 89.0% | 76.9% |
| 3786516 | 5069.1.1.4 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Ferric_reduct | 0.66 | 56.0 | 4.82e-01 | 91.6% | 77.5% |
| 2492086 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.65 | 55.0 | 5.71e-01 | 91.0% | 97.3% |
| 3565707 | 601.11.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain › Perilipin | 0.64 | 57.0 | 5.26e-01 | 92.9% | 95.3% |
| 3726914 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.64 | 54.0 | 5.64e-01 | 92.9% | 96.6% |
| 3187296 | 603.1.1.98 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE, Syntaxin_2 | 0.64 | 45.0 | 4.05e-01 | 71.6% | 95.8% |
| 3691781 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.64 | 53.0 | 4.91e-01 | 89.0% | 80.0% |
| 5079776 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.64 | 58.0 | 5.41e-01 | 96.8% | 80.5% |
| 3905731 | 601.11.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain › Perilipin | 0.63 | 55.0 | 4.86e-01 | 93.5% | 94.5% |
| 2810966 | 5069.1.1.3 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cyt_bd_oxida_I | 0.62 | 53.0 | 4.17e-01 | 91.6% | 85.0% |
| 3513656 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.62 | 52.0 | 4.83e-01 | 89.0% | 87.2% |
| 3174832 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.62 | 55.0 | 3.58e-01 | 97.4% | 69.2% |
| 3261237 | 5069.1.1.7 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 | 0.62 | 51.0 | 5.03e-01 | 87.7% | 83.6% |
| 4946155 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.62 | 54.0 | 5.17e-01 | 93.5% | 92.6% |
| 3953703 | 601.33.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD | 0.62 | 49.0 | 5.29e-01 | 89.0% | 99.2% |
| 3974430 | 601.4.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › 4HB_MCP_1 | 0.61 | 51.0 | 5.32e-01 | 92.3% | 97.9% |
| 3752923 | 601.4.1.42 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TMEM138 | 0.61 | 52.0 | 5.20e-01 | 90.3% | 92.3% |
| 3277363 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.61 | 50.0 | 5.27e-01 | 91.0% | 100.0% |
| 3573786 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.61 | 52.0 | 4.73e-01 | 90.3% | 71.5% |
| 4430792 | 192.29.1.52 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Anthrone_oxy | 0.60 | 50.0 | 4.92e-01 | 89.7% | 95.1% |
| 3939708 | 601.24.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 0.60 | 41.0 | 4.73e-01 | 89.7% | 97.3% |
| 5005248 | 601.1.1.16 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › SpoIIM | 0.59 | 44.0 | 4.45e-01 | 78.1% | 85.8% |
| 3471757 | 192.29.1.140 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Frag1 | 0.58 | 48.0 | 4.93e-01 | 87.7% | 100.0% |
| 4974984 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.58 | 45.0 | 4.09e-01 | 81.9% | 94.1% |
| 4028540 | 3543.1.1.3 ↗ | alpha complex topology › Acid-activated urea channel › Acid-activated urea channel › Acid-activated urea channel › YrhK | 0.58 | 51.0 | 4.78e-01 | 94.2% | 98.9% |
| 3681194 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.56 | 41.0 | 4.44e-01 | 75.5% | 100.0% |
| 4000663 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.56 | 48.0 | 3.76e-01 | 91.6% | 75.0% |
| 3178176 | 3745.1.1.1 ↗ | alpha bundles › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Na_Ca_ex | 0.55 | 47.0 | 3.41e-01 | 92.3% | 81.8% |
| 3929335 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.54 | 44.0 | 3.81e-01 | 85.8% | 68.3% |
| 3473688 | 3567.1.1.82 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › Frag1 | 0.54 | 48.0 | 4.22e-01 | 97.4% | 74.9% |
| 3688960 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.54 | 44.0 | 4.00e-01 | 86.5% | 72.7% |
| 3247271 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.53 | 44.0 | 3.63e-01 | 89.7% | 58.9% |
| 3254587 | 1174.1.1.7 ↗ | alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 › Frag1 | 0.53 | 46.0 | 4.09e-01 | 94.8% | 73.2% |
| 4029302 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.53 | 47.0 | 4.43e-01 | 99.4% | 93.2% |
| 3438770 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.51 | 42.0 | 4.12e-01 | 87.7% | 83.6% |
| 5045646 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.51 | 41.0 | 4.23e-01 | 85.2% | 98.6% |
| 3454885 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.51 | 37.0 | 3.91e-01 | 75.5% | 93.3% |
| 3322979 | 5058.1.1.38 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MSL2_3 | 0.51 | 38.0 | 3.69e-01 | 78.7% | 84.6% |
| 3444933 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.50 | 38.0 | 3.95e-01 | 80.6% | 91.7% |
D4
medium
residues 361-487
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05235.20 best | CHAD | 63.5 | 4.10e-17 | 67.7% | 36.8% |
CATH (64)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3e0sA00 | 1.40.20.10 | Mainly Alpha › Alpha solenoid › CHAD domain › CHAD domain | 0.88 | 84.0 | 6.15e-01 | 100.0% | 44.3% |
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.80 | 61.0 | 5.27e-01 | 78.7% | 87.8% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.75 | 47.0 | 4.92e-01 | 88.2% | 69.0% |
| 6lw5A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.73 | 63.0 | 4.77e-01 | 94.5% | 83.4% |
| 1nzeA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.72 | 57.0 | 6.05e-01 | 100.0% | 94.6% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.72 | 50.0 | 5.00e-01 | 100.0% | 69.5% |
| 6ko5A02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.71 | 60.0 | 4.60e-01 | 91.3% | 84.9% |
| 2yevA03 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.69 | 63.0 | 5.54e-01 | 98.4% | 75.0% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.69 | 60.0 | 5.92e-01 | 100.0% | 86.1% |
| 3ajmB02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.69 | 56.0 | 5.53e-01 | 100.0% | 82.0% |
| 3tulB00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.69 | 51.0 | 5.06e-01 | 77.2% | 91.0% |
| 2v0oB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.69 | 58.0 | 4.47e-01 | 89.8% | 76.0% |
| 1qgtB00 | 1.10.4090.10 | Mainly Alpha › Orthogonal Bundle › Hepatitis B viral capsid (hbcag) fold › Viral capsid, core domain supefamily, Hepatitis B virus | 0.68 | 47.0 | 4.58e-01 | 78.7% | 62.9% |
| 2pmsC00 | 6.10.140.920 | Special › Helix non-globular › Helix Hairpins › | 0.68 | 51.0 | 5.47e-01 | 78.0% | 96.3% |
| 2x0cA01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.68 | 57.0 | 5.14e-01 | 91.3% | 82.0% |
| 3ieeA02 | 1.20.58.820 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Uncharacterised protein PF12889, C-terminal DUF3829 | 0.67 | 52.0 | 5.65e-01 | 96.9% | 100.0% |
| 2l10A00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.67 | 56.0 | 5.22e-01 | 100.0% | 72.2% |
| 2l6hA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.67 | 57.0 | 5.38e-01 | 100.0% | 76.6% |
| 3ggyA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.67 | 46.0 | 4.04e-01 | 70.1% | 76.3% |
| 7metA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.66 | 45.0 | 3.36e-01 | 97.6% | 28.5% |
| 4yjwA00 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.66 | 59.0 | 5.57e-01 | 99.2% | 93.5% |
| 1st6A04 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.65 | 55.0 | 5.70e-01 | 99.2% | 97.4% |
| 2e87A01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.65 | 58.0 | 5.39e-01 | 97.6% | 99.4% |
| 2ap3A00 | 1.20.120.570 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YkyA-like | 0.65 | 59.0 | 5.10e-01 | 98.4% | 84.9% |
| 1qv9A02 | 6.10.140.120 | Special › Helix non-globular › Helix Hairpins › | 0.65 | 43.0 | 4.74e-01 | 78.7% | 83.5% |
| 3ddlA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.65 | 53.0 | 4.28e-01 | 89.0% | 82.5% |
| 3rguB00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.64 | 42.0 | 4.82e-01 | 78.7% | 95.4% |
| 8hk0C01 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.64 | 48.0 | 4.55e-01 | 78.7% | 66.0% |
| 4k0dA00 | 1.20.120.1730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.64 | 56.0 | 5.39e-01 | 100.0% | 84.6% |
| 4iggB02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.64 | 54.0 | 5.53e-01 | 95.3% | 94.2% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.63 | 55.0 | 5.50e-01 | 100.0% | 94.5% |
| 7q37A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.63 | 52.0 | 4.40e-01 | 89.0% | 85.5% |
| 1b68A00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.63 | 54.0 | 5.28e-01 | 92.1% | 100.0% |
| 1oahA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.63 | 44.0 | 4.26e-01 | 81.1% | 64.1% |
| 6xj1A01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.63 | 45.0 | 3.70e-01 | 75.6% | 83.3% |
| 1jmwA00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.62 | 56.0 | 5.38e-01 | 100.0% | 88.4% |
| 6h2dS01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.62 | 53.0 | 4.43e-01 | 94.5% | 85.2% |
| 3qo8A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.62 | 48.0 | 5.28e-01 | 81.9% | 100.0% |
| 2d4uB00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.61 | 56.0 | 5.22e-01 | 100.0% | 84.5% |
| 3lssA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.61 | 48.0 | 5.05e-01 | 81.9% | 100.0% |
| 4fzsA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.60 | 49.0 | 4.19e-01 | 88.2% | 86.6% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.60 | 44.0 | 4.61e-01 | 79.5% | 83.9% |
| 3frrA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.60 | 42.0 | 3.74e-01 | 72.4% | 55.4% |
| 3o6xA02 | 1.20.120.1560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.59 | 44.0 | 4.22e-01 | 78.0% | 75.7% |
| 4k7rA01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.59 | 50.0 | 3.67e-01 | 93.7% | 93.7% |
| 6vq6G02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.58 | 53.0 | 4.67e-01 | 100.0% | 83.2% |
| 2dq0A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.58 | 46.0 | 4.91e-01 | 96.1% | 100.0% |
| 1t72A02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.58 | 42.0 | 4.74e-01 | 86.6% | 99.0% |
| 4q4hB01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.58 | 45.0 | 3.30e-01 | 81.9% | 95.5% |
| 5azpB01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.57 | 44.0 | 3.20e-01 | 81.1% | 95.7% |
| 1st6A03 | 1.20.120.810 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle | 0.57 | 51.0 | 4.23e-01 | 100.0% | 54.6% |
| 4mt0A01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.57 | 50.0 | 3.69e-01 | 100.0% | 91.0% |
| 1h6gA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.57 | 48.0 | 4.92e-01 | 92.1% | 100.0% |
| 5j1hA01 | 1.20.58.1060 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 47.0 | 4.21e-01 | 91.3% | 82.4% |
| 2d1lA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.56 | 43.0 | 3.43e-01 | 79.5% | 78.7% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 49.0 | 4.27e-01 | 96.1% | 85.4% |
| 1u7lA02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.56 | 50.0 | 4.44e-01 | 99.2% | 88.5% |
| 6gyhA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.55 | 48.0 | 4.00e-01 | 99.2% | 53.3% |
| 4mt4A00 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.54 | 47.0 | 3.28e-01 | 98.4% | 87.9% |
| 5azsC01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.54 | 47.0 | 3.47e-01 | 98.4% | 90.5% |
| 3ck6C02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.54 | 42.0 | 4.34e-01 | 86.6% | 89.1% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.54 | 42.0 | 4.57e-01 | 89.0% | 99.1% |
| 3s84A02 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.53 | 40.0 | 3.72e-01 | 76.4% | 82.2% |
| 1yc9A01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.53 | 44.0 | 3.29e-01 | 90.6% | 95.1% |
ECOD (59)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2492497 | 601.33.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD | 0.90 | 85.0 | 8.00e-01 | 100.0% | 96.6% |
| 4401479 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.85 | 62.0 | 6.95e-01 | 74.8% | 100.0% |
| 5081365 | 601.33.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain | 0.83 | 78.0 | 7.41e-01 | 100.0% | 96.6% |
| 5002024 | 601.33.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD | 0.83 | 78.0 | 6.90e-01 | 100.0% | 79.4% |
| 3684830 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.81 | 61.0 | 6.84e-01 | 77.2% | 100.0% |
| 3953704 | 601.33.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD | 0.79 | 73.0 | 6.93e-01 | 100.0% | 92.0% |
| 3285252 | 601.33.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD | 0.78 | 72.0 | 6.71e-01 | 100.0% | 92.9% |
| 3957736 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.77 | 58.0 | 6.45e-01 | 82.7% | 98.0% |
| 3513671 | 601.33.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain | 0.77 | 55.0 | 6.15e-01 | 100.0% | 94.9% |
| 3962505 | 601.33.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD | 0.77 | 71.0 | 5.62e-01 | 100.0% | 55.2% |
| 4435642 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.75 | 53.0 | 5.85e-01 | 71.7% | 100.0% |
| 3953703 | 601.33.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD | 0.75 | 68.0 | 6.74e-01 | 100.0% | 97.7% |
| 3175356 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.75 | 63.0 | 5.67e-01 | 90.6% | 97.7% |
| 3229637 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.75 | 61.0 | 4.40e-01 | 86.6% | 81.2% |
| 3979143 | 601.33.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD | 0.74 | 58.0 | 5.69e-01 | 100.0% | 76.3% |
| 3442053 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.74 | 68.0 | 5.82e-01 | 100.0% | 99.5% |
| 4488596 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.74 | 55.0 | 5.75e-01 | 77.2% | 93.0% |
| 3769618 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.74 | 64.0 | 4.70e-01 | 93.7% | 75.7% |
| 4274219 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.73 | 54.0 | 5.60e-01 | 77.2% | 89.2% |
| 3441289 | 3684.1.1.19 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › DUF1110 | 0.73 | 66.0 | 5.97e-01 | 100.0% | 98.9% |
| 3236387 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.72 | 58.0 | 4.54e-01 | 84.3% | 87.7% |
| 4048446 | 148.1.3.26 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_9 | 0.72 | 54.0 | 4.44e-01 | 78.7% | 87.8% |
| 4016004 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.71 | 63.0 | 5.60e-01 | 96.9% | 73.3% |
| 3684255 | 601.1.2.74 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Rx_N | 0.71 | 53.0 | 5.17e-01 | 78.7% | 75.0% |
| 3466941 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.70 | 63.0 | 5.29e-01 | 97.6% | 85.9% |
| 3454282 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.70 | 63.0 | 5.63e-01 | 97.6% | 97.1% |
| 4077176 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.70 | 48.0 | 5.60e-01 | 85.8% | 98.9% |
| 5009681 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.70 | 62.0 | 6.08e-01 | 99.2% | 98.6% |
| 3398787 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.69 | 52.0 | 4.84e-01 | 78.7% | 71.2% |
| 4124285 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.69 | 59.0 | 5.67e-01 | 99.2% | 82.1% |
| 3654904 | 3755.4.1.17 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Rx_N | 0.68 | 52.0 | 5.07e-01 | 80.3% | 75.7% |
| 2324029 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.68 | 58.0 | 5.90e-01 | 100.0% | 95.1% |
| 2492086 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.67 | 62.0 | 5.92e-01 | 100.0% | 89.8% |
| 4567743 | 601.14.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin | 0.66 | 60.0 | 5.34e-01 | 100.0% | 70.0% |
| 5052771 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.66 | 55.0 | 5.72e-01 | 100.0% | 98.3% |
| None | — | 0.66 | 58.0 | 4.34e-01 | 97.6% | 79.7% | |
| 3387116 | 601.14.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin | 0.65 | 55.0 | 5.39e-01 | 99.2% | 85.2% |
| 5028018 | 5045.1.1.0 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A | 0.64 | 52.0 | 4.03e-01 | 88.2% | 86.7% |
| 3685679 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.64 | 50.0 | 4.73e-01 | 82.7% | 96.1% |
| 3216332 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.64 | 57.0 | 5.75e-01 | 100.0% | 99.2% |
| 3573786 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.63 | 57.0 | 4.88e-01 | 100.0% | 68.0% |
| 4959549 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.62 | 55.0 | 4.87e-01 | 100.0% | 66.5% |
| 4013887 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.62 | 55.0 | 5.40e-01 | 98.4% | 95.7% |
| 3762118 | 633.21.1.23 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 | 0.62 | 47.0 | 4.31e-01 | 78.7% | 67.9% |
| 3576633 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.62 | 51.0 | 4.05e-01 | 89.8% | 78.1% |
| 4987042 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.62 | 54.0 | 5.36e-01 | 100.0% | 89.6% |
| 3551634 | 1075.4.1.9 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_tran+ABC_membrane | 0.60 | 49.0 | 2.91e-01 | 86.6% | 63.7% |
| 3253936 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.60 | 51.0 | 5.08e-01 | 100.0% | 88.1% |
| 3724303 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.60 | 53.0 | 5.16e-01 | 99.2% | 98.6% |
| 3288367 | 150.8.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE › PPE | 0.60 | 48.0 | 4.40e-01 | 85.8% | 97.1% |
| 1758799 | 601.16.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase | 0.60 | 53.0 | 5.23e-01 | 100.0% | 92.1% |
| 3924319 | 5001.1.1.106 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Str | 0.60 | 54.0 | 4.14e-01 | 100.0% | 86.8% |
| 3224746 | 601.1.2.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin | 0.60 | 53.0 | 5.33e-01 | 96.9% | 100.0% |
| 3313420 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.59 | 50.0 | 4.92e-01 | 92.9% | 92.1% |
| 3598986 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.58 | 51.0 | 4.63e-01 | 96.9% | 85.9% |
| 3290567 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.57 | 42.0 | 4.54e-01 | 81.1% | 94.3% |
| 3971458 | 5085.1.1.0 ↗ | a+b duplicates or obligate multimers › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.56 | 49.0 | 3.47e-01 | 99.2% | 91.3% |
| 3949218 | 5085.1.1.1 ↗ | a+b duplicates or obligate multimers › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › OEP | 0.52 | 43.0 | 2.97e-01 | 89.0% | 67.2% |
| 3534202 | 3602.1.1.16 ↗ | alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › SHCBP_N | 0.52 | 39.0 | 4.26e-01 | 85.0% | 100.0% |