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CAKLQF020000007.1__CAH1081687.1__SAMEA5780031_01640__00047
Bact-VirCAKLQF020000007.1__CAH1081687.1__SAMEA5780031_01640__00047
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-71
D2
medium
residues 72-163
Domain cluster:
representative
CATH (27)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 8e9gK01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.70 | 56.0 | 5.63e-01 | 100.0% | 87.9% |
| 2uuiA00 | 1.20.120.550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain | 0.69 | 47.0 | 3.98e-01 | 72.8% | 41.9% |
| 1x04A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.65 | 54.0 | 4.29e-01 | 93.5% | 82.0% |
| 2wl8C00 | 1.20.120.900 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pex19, mPTS binding domain | 0.64 | 46.0 | 4.41e-01 | 83.7% | 64.2% |
| 1l7vA00 | 1.10.3470.10 | Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC | 0.63 | 51.0 | 3.55e-01 | 90.2% | 70.6% |
| 2hytA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.62 | 56.0 | 4.41e-01 | 100.0% | 72.5% |
| 8sbeA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.62 | 55.0 | 4.33e-01 | 100.0% | 47.6% |
| 2efkA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.61 | 51.0 | 3.77e-01 | 93.5% | 82.4% |
| 2dq0A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.60 | 45.0 | 4.29e-01 | 79.3% | 92.5% |
| 4qgpB00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.58 | 38.0 | 3.68e-01 | 70.7% | 57.9% |
| 3rlfF01 | 1.20.58.370 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › MalF N-terminal region-like | 0.58 | 45.0 | 4.66e-01 | 98.9% | 90.7% |
| 2qr4A01 | 1.20.140.70 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Oligopeptidase f, N-terminal domain | 0.57 | 49.0 | 4.20e-01 | 97.8% | 76.9% |
| 1xwjA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.57 | 44.0 | 3.99e-01 | 85.9% | 60.0% |
| 2wbiB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.56 | 46.0 | 3.85e-01 | 89.1% | 53.8% |
| 5xdcB01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.55 | 43.0 | 4.07e-01 | 83.7% | 100.0% |
| 7ae2A01 | 1.20.120.580 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like | 0.55 | 46.0 | 4.11e-01 | 93.5% | 81.0% |
| 4nleA01 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.55 | 42.0 | 3.14e-01 | 83.7% | 34.8% |
| 2lqgA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.55 | 41.0 | 3.68e-01 | 81.5% | 54.3% |
| 2pmiB00 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.55 | 36.0 | 2.79e-01 | 76.1% | 29.1% |
| 2ix5A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.54 | 45.0 | 3.78e-01 | 90.2% | 53.5% |
| 6fndA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.54 | 38.0 | 3.10e-01 | 90.2% | 37.1% |
| 1e91A00 | 1.20.1160.11 | Mainly Alpha › Up-down Bundle › Paired amphipathic helix 2 (pah2 repeat) › Paired amphipathic helix | 0.53 | 36.0 | 3.74e-01 | 92.4% | 75.3% |
| 3p4tA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.53 | 42.0 | 3.71e-01 | 91.3% | 70.7% |
| 4dwlA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.53 | 44.0 | 4.22e-01 | 100.0% | 79.6% |
| 7zxkC01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.51 | 42.0 | 3.58e-01 | 89.1% | 86.7% |
| 1rx0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.51 | 44.0 | 3.78e-01 | 97.8% | 70.3% |
| 5iduC03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.51 | 40.0 | 3.49e-01 | 91.3% | 66.0% |
ECOD (34)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3600055 | 633.6.1.0 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like | 0.67 | 47.0 | 4.24e-01 | 71.7% | 76.0% |
| 3414399 | 5086.1.1.106 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › DUF725 | 0.67 | 46.0 | 3.82e-01 | 71.7% | 71.2% |
| 4567939 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.67 | 60.0 | 4.54e-01 | 100.0% | 75.9% |
| 4982694 | 3843.1.1.35 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › DUF1634 | 0.65 | 59.0 | 5.79e-01 | 100.0% | 100.0% |
| 3945031 | 5086.1.1.86 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_YBHG | 0.65 | 45.0 | 4.03e-01 | 71.7% | 80.0% |
| 3675343 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.64 | 58.0 | 4.92e-01 | 100.0% | 64.0% |
| 3928006 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.64 | 53.0 | 3.84e-01 | 93.5% | 37.5% |
| 4586824 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.63 | 51.0 | 3.85e-01 | 89.1% | 76.1% |
| 3213000 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.60 | 48.0 | 3.72e-01 | 88.0% | 73.0% |
| 4501827 | 3843.1.1.1 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q2 | 0.60 | 52.0 | 5.07e-01 | 100.0% | 91.4% |
| 3927756 | 3817.1.1.1 ↗ | alpha bundles › Peroxisomal biogenesis factor 19 › Peroxisomal biogenesis factor 19 › Peroxisomal biogenesis factor 19 › Pex19 | 0.60 | 45.0 | 4.15e-01 | 83.7% | 61.7% |
| 3928106 | 632.7.1.25 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › PF27508 | 0.59 | 44.0 | 4.10e-01 | 82.6% | 61.7% |
| 3653618 | 5069.1.3.69 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › ETR1_N | 0.59 | 48.0 | 4.76e-01 | 91.3% | 87.4% |
| 3791831 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.59 | 47.0 | 3.64e-01 | 89.1% | 73.6% |
| 5005612 | 604.39.1.9 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › Vut_1 | 0.59 | 51.0 | 3.88e-01 | 98.9% | 51.3% |
| 3846684 | 1174.1.1.1 ↗ | alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 › TMEM175 | 0.58 | 51.0 | 3.89e-01 | 100.0% | 77.4% |
| 4467968 | 605.4.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein | 0.58 | 44.0 | 4.08e-01 | 87.0% | 62.5% |
| 4192664 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.58 | 46.0 | 3.29e-01 | 91.3% | 26.5% |
| 3989648 | 1203.1.2.17 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ABC_membrane | 0.58 | 45.0 | 3.52e-01 | 83.7% | 64.0% |
| 3924462 | 632.1.1.11 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › HYOU1_C | 0.58 | 44.0 | 4.03e-01 | 82.6% | 61.7% |
| 4111212 | 622.4.1.30 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › ETR1_N | 0.58 | 46.0 | 4.56e-01 | 91.3% | 82.0% |
| 3377749 | 3843.1.1.15 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › ETR1_N | 0.57 | 46.0 | 4.51e-01 | 91.3% | 82.0% |
| 3993967 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.56 | 46.0 | 4.10e-01 | 92.4% | 90.4% |
| 3215718 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.55 | 43.0 | 4.54e-01 | 88.0% | 100.0% |
| 3313517 | 7013.1.1.1 ↗ | alpha bundles › Ribosome assembly factor Efg1-like › Ribosome assembly factor Efg1-like › Ribosome assembly factor Efg1-like › Efg1 | 0.54 | 44.0 | 3.77e-01 | 88.0% | 60.0% |
| 3746208 | 601.18.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › Got1 | 0.54 | 46.0 | 3.99e-01 | 100.0% | 61.0% |
| 3973497 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 40.0 | 3.06e-01 | 83.7% | 60.4% |
| 3833252 | 4106.1.1.0 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack | 0.53 | 43.0 | 3.77e-01 | 90.2% | 74.5% |
| 4250108 | 5069.1.3.1 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › Sdh_cyt | 0.52 | 41.0 | 3.79e-01 | 89.1% | 73.6% |
| 3820263 | 7016.1.1.0 ↗ | extended segments › Palmitoyltransferase DHHC C-terminal domain › Palmitoyltransferase DHHC C-terminal domain › Palmitoyltransferase DHHC C-terminal domain | 0.52 | 44.0 | 3.88e-01 | 97.8% | 81.4% |
| 3612403 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.51 | 44.0 | 3.86e-01 | 97.8% | 73.1% |
| 3743177 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.51 | 43.0 | 3.77e-01 | 94.6% | 68.3% |
| 3171135 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.51 | 44.0 | 3.53e-01 | 98.9% | 55.3% |
| 3240691 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.50 | 43.0 | 3.88e-01 | 97.8% | 71.9% |