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CAKLQF020000008.1__CAH1081864.1__SAMEA5780031_01767__00012

Bact-Vir

CAKLQF020000008.1__CAH1081864.1__SAMEA5780031_01767__00012

Identity

Kingdom:
phage

Quality

95.9 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 39-183
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01872.23 best RibD_C 58.1 1.60e-15 100.0% 80.7%
CATH (43)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3jtwA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.89 77.0 7.13e-01 100.0% 73.9%
3ky8A01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.86 75.0 7.02e-01 100.0% 75.9%
1cz3B00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.84 70.0 6.66e-01 100.0% 75.0%
5eccA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.82 64.0 6.25e-01 100.0% 75.2%
1ao8A00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.77 64.0 6.19e-01 100.0% 77.8%
6pf8A01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.75 67.0 6.20e-01 100.0% 76.7%
2g6vA02 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.74 70.0 5.96e-01 100.0% 78.4%
3k2hA01 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.73 66.0 6.02e-01 100.0% 74.3%
1j3jB00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.71 67.0 5.79e-01 100.0% 69.0%
1bozA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.70 65.0 5.96e-01 100.0% 77.4%
4ha7B00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.65 60.0 5.33e-01 100.0% 73.2%
7jt8I02 3.90.190.20 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain 0.64 45.0 4.53e-01 71.7% 82.6%
7bmfA01 3.90.1640.30 Alpha Beta › Alpha-Beta Complex › inorganic pyrophosphatase (n-terminal core) › 0.59 42.0 3.87e-01 94.5% 56.2%
1ti2A03 3.40.228.10 Alpha Beta › 3-Layer(aba) Sandwich › Dimethylsulfoxide Reductase; domain 2 › Dimethylsulfoxide Reductase, domain 2 0.59 49.0 3.93e-01 89.0% 81.2%
2jhpA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.59 54.0 4.30e-01 100.0% 84.1%
6hxqA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.59 46.0 4.85e-01 93.1% 93.0%
1jr2A02 3.40.50.10090 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.58 46.0 4.68e-01 83.4% 87.1%
3rhzA02 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.56 42.0 4.09e-01 93.1% 72.0%
2frxB01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 50.0 4.00e-01 100.0% 61.4%
3vywA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 49.0 4.24e-01 100.0% 74.5%
2vxbA02 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.55 28.0 3.47e-01 75.9% 81.5%
1yc5A01 3.40.50.1220 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain 0.55 44.0 4.39e-01 94.5% 83.3%
3ucxA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 49.0 4.07e-01 99.3% 96.5%
2dtxA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 49.0 4.08e-01 99.3% 93.3%
2ffeA01 3.40.50.10680 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › CofD-like domains 0.54 46.0 4.01e-01 92.4% 88.2%
1nf8A00 3.40.50.850 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Isochorismatase-like 0.54 46.0 4.12e-01 93.1% 83.6%
2ggsA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 47.0 4.21e-01 96.6% 95.6%
3un1C00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.53 46.0 3.96e-01 95.9% 95.3%
1cxsA02 3.40.228.10 Alpha Beta › 3-Layer(aba) Sandwich › Dimethylsulfoxide Reductase; domain 2 › Dimethylsulfoxide Reductase, domain 2 0.53 46.0 3.84e-01 94.5% 82.9%
3hbmA01 3.40.50.11190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.52 45.0 4.66e-01 95.2% 98.6%
3brsA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 41.0 4.26e-01 100.0% 91.0%
3fj1A01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.52 36.0 3.36e-01 91.7% 53.4%
2ymmB01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.52 46.0 4.52e-01 97.2% 94.2%
7og5F01 3.40.50.1010 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease 0.52 36.0 3.57e-01 71.0% 94.1%
3gqvA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 47.0 4.28e-01 99.3% 82.6%
3ry7A00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.51 45.0 3.59e-01 97.2% 90.4%
2i9uA02 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.51 46.0 3.64e-01 100.0% 96.4%
7ef6A01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.51 41.0 4.02e-01 86.2% 89.3%
5t5dA00 3.40.35.10 Alpha Beta › 3-Layer(aba) Sandwich › Fructose Permease › Phosphotransferase system, sorbose subfamily IIB component 0.51 45.0 4.46e-01 96.6% 96.0%
5tx7A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 46.0 4.20e-01 99.3% 92.1%
5l4lA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 43.0 3.54e-01 94.5% 92.4%
6p2iA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.50 45.0 4.21e-01 98.6% 91.1%
1u7zC00 3.40.50.10300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › CoaB-like 0.50 43.0 3.81e-01 95.2% 84.9%
ECOD (49)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5073892 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.95 92.0 8.24e-01 100.0% 76.3%
3277763 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.94 88.0 7.91e-01 100.0% 75.1%
3282759 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.93 88.0 7.97e-01 100.0% 77.0%
3279668 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.92 87.0 7.83e-01 100.0% 76.2%
3278932 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.92 88.0 7.93e-01 100.0% 77.2%
3286316 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.91 86.0 7.80e-01 100.0% 76.8%
5058063 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.89 76.0 7.07e-01 100.0% 73.6%
136641 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.89 77.0 7.13e-01 100.0% 73.9%
3590464 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.88 75.0 7.05e-01 100.0% 74.6%
3974710 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.88 75.0 6.95e-01 100.0% 73.1%
3010946 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.86 76.0 7.01e-01 100.0% 75.6%
160146 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.84 73.0 6.76e-01 100.0% 74.0%
4123104 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.84 71.0 6.74e-01 100.0% 77.6%
3282327 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.84 71.0 6.36e-01 100.0% 66.2%
5030442 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.83 72.0 6.75e-01 100.0% 77.1%
3278543 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.82 77.0 6.95e-01 100.0% 79.5%
3284365 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.81 77.0 6.89e-01 100.0% 77.2%
4279950 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.79 66.0 6.27e-01 100.0% 75.8%
235716 7501.1.1.2 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C 0.74 70.0 6.08e-01 100.0% 79.8%
185430 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.73 66.0 6.05e-01 100.0% 74.7%
3232633 7501.1.1.1 a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › DHFR_1 0.71 67.0 6.15e-01 100.0% 80.0%
4367125 2003.1.8.4 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › MurCD/PglD N-terminal domain-like › MurD-like_N 0.65 39.0 4.84e-01 75.9% 100.0%
3287625 2003.1.1.32 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › CoA_binding 0.62 45.0 4.56e-01 92.4% 76.4%
3163704 7523.1.1.30 a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › SBP_bac_11 0.60 34.0 3.80e-01 80.7% 68.7%
1521280 7523.1.1.30 a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › SBP_bac_11 0.60 35.0 4.39e-01 80.0% 98.8%
4995806 7555.1.1.0 a/b three-layered sandwiches › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related › Alpha-2,3/8-sialyltransferase CstII-related 0.60 52.0 4.51e-01 93.8% 87.3%
3394200 7523.1.1.0 a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II 0.58 34.0 3.93e-01 76.6% 79.0%
185903 2003.1.5.43 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Orbi_VP4 0.58 53.0 4.77e-01 99.3% 93.4%
None 0.58 48.0 3.95e-01 90.3% 66.5%
3415022 7512.1.1.83 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDPGT, EryCIII-like_C 0.57 43.0 3.00e-01 90.3% 24.9%
3496182 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.57 50.0 3.84e-01 96.6% 86.6%
3604334 7518.1.1.1 a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C 0.57 45.0 4.59e-01 84.8% 86.4%
4940244 2003.4.1.0 a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes 0.56 45.0 4.41e-01 86.2% 94.4%
3402033 7512.1.1.1 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDPGT 0.55 49.0 4.09e-01 97.2% 94.1%
3226175 2003.1.1.11 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › 3Beta_HSD 0.55 49.0 3.53e-01 97.2% 81.4%
4411449 2003.2.1.1 a/b three-layered sandwiches › Rossmann-like › Formate dehydrogenase/DMSO reductase, domains 2 and 3 › Formate dehydrogenase/DMSO reductase, domains 2 and 3 › Molybdopterin 0.55 43.0 4.50e-01 82.8% 91.9%
153143 2003.1.5.49 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_30 0.55 50.0 3.94e-01 100.0% 57.8%
3394489 7512.1.1.0 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.55 49.0 4.09e-01 97.9% 96.0%
4601394 2003.2.1.0 a/b three-layered sandwiches › Rossmann-like › Formate dehydrogenase/DMSO reductase, domains 2 and 3 › Formate dehydrogenase/DMSO reductase, domains 2 and 3 0.54 42.0 3.93e-01 82.8% 93.3%
4974864 7512.1.1.32 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_trans_1_4 0.53 44.0 4.14e-01 88.3% 85.0%
3712297 2003.1.1.3 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short 0.53 47.0 4.03e-01 97.2% 99.6%
2881682 2003.2.1.0 a/b three-layered sandwiches › Rossmann-like › Formate dehydrogenase/DMSO reductase, domains 2 and 3 › Formate dehydrogenase/DMSO reductase, domains 2 and 3 0.53 43.0 3.84e-01 85.5% 85.9%
4339836 2006.1.4.17 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › DUF188 0.53 39.0 3.92e-01 83.4% 75.9%
4990295 2003.1.1.65 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_7 0.52 40.0 4.14e-01 100.0% 85.7%
3722335 2003.1.1.37 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › 2-Hacid_dh_C 0.52 47.0 4.25e-01 99.3% 91.8%
3942834 2003.1.1.37 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › 2-Hacid_dh_C 0.51 46.0 4.29e-01 99.3% 92.4%
4947870 2003.1.1.51 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › DFP 0.51 45.0 4.04e-01 97.9% 86.8%
2068260 2003.1.1.37 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › 2-Hacid_dh_C 0.51 46.0 4.01e-01 100.0% 75.6%
3603289 2003.1.5.15 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › FtsJ 0.50 45.0 4.30e-01 100.0% 83.3%