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CAKLQF020000008.1__CAH1082041.1__SAMEA5780031_01893__00138
Bact-VirCAKLQF020000008.1__CAH1082041.1__SAMEA5780031_01893__00138
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 332-432
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05525.20 best | Branch_AA_trans | 86.0 | 3.80e-24 | 97.0% | 22.8% |
CATH (49)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2oauA01 | 1.10.287.1260 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.70 | 48.0 | 4.84e-01 | 70.3% | 75.5% |
| 3s84A02 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.65 | 58.0 | 5.04e-01 | 99.0% | 90.4% |
| 1fouA01 | 1.10.246.30 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.64 | 45.0 | 5.08e-01 | 86.1% | 100.0% |
| 3ljbA00 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.64 | 57.0 | 4.44e-01 | 100.0% | 74.9% |
| 4l6rA02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.61 | 51.0 | 3.71e-01 | 92.1% | 35.6% |
| 3lmfA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.61 | 42.0 | 4.18e-01 | 79.2% | 67.0% |
| 1otkA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.61 | 44.0 | 3.34e-01 | 75.2% | 91.0% |
| 2v0oB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.60 | 52.0 | 3.83e-01 | 95.0% | 78.6% |
| 7dluA01 | 1.10.287.1260 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.60 | 48.0 | 4.75e-01 | 88.1% | 82.9% |
| 2kbbA00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.59 | 51.0 | 4.32e-01 | 96.0% | 98.9% |
| 3o7qA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.59 | 40.0 | 3.29e-01 | 70.3% | 96.9% |
| 2bl2A00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.59 | 53.0 | 4.60e-01 | 100.0% | 76.9% |
| 3dyjA01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.59 | 50.0 | 4.30e-01 | 95.0% | 60.8% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.59 | 45.0 | 4.14e-01 | 89.1% | 61.3% |
| 1qkrB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.59 | 48.0 | 4.05e-01 | 91.1% | 56.7% |
| 3t9oB00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.59 | 47.0 | 4.51e-01 | 92.1% | 74.2% |
| 2uxwA04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.58 | 49.0 | 4.55e-01 | 93.1% | 85.4% |
| 3vkgA09 | 1.20.920.30 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › | 0.58 | 43.0 | 3.93e-01 | 90.1% | 56.2% |
| 6me6B02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.58 | 49.0 | 3.64e-01 | 96.0% | 45.7% |
| 6oi7A01 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.57 | 46.0 | 3.67e-01 | 85.1% | 69.4% |
| 3i2wA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.57 | 50.0 | 3.80e-01 | 99.0% | 85.3% |
| 4jvsA01 | 1.20.120.1700 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.57 | 46.0 | 4.31e-01 | 88.1% | 70.6% |
| 2z1qB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.56 | 45.0 | 4.09e-01 | 86.1% | 64.7% |
| 3i1aA03 | 1.20.58.840 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 43.0 | 4.17e-01 | 81.2% | 95.7% |
| 4f0uA00 | 1.10.490.20 | Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins | 0.56 | 44.0 | 3.80e-01 | 84.2% | 81.2% |
| 3frrA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.56 | 47.0 | 3.91e-01 | 95.0% | 92.5% |
| 7w5lA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.56 | 40.0 | 3.03e-01 | 75.2% | 75.6% |
| 2okuA00 | 1.20.120.470 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Acyl-CoA dehydrogenase, C-terminal domain | 0.56 | 47.0 | 4.45e-01 | 95.0% | 81.1% |
| 6cnzF00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.55 | 45.0 | 3.97e-01 | 94.1% | 58.2% |
| 3r64A01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.55 | 43.0 | 3.12e-01 | 83.2% | 42.8% |
| 3pltA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.55 | 47.0 | 3.80e-01 | 98.0% | 87.4% |
| 4akvA02 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.55 | 46.0 | 3.88e-01 | 98.0% | 94.7% |
| 2etdA00 | 1.20.1440.20 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain | 0.54 | 38.0 | 3.42e-01 | 71.3% | 86.5% |
| 5ts9B00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.54 | 43.0 | 3.81e-01 | 91.1% | 55.9% |
| 1w9rA00 | 1.20.58.440 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › choline binding protein A | 0.54 | 46.0 | 4.44e-01 | 96.0% | 83.2% |
| 3ggyA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.54 | 47.0 | 3.93e-01 | 99.0% | 89.2% |
| 7tj9A01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.54 | 37.0 | 3.66e-01 | 85.1% | 67.0% |
| 2rfqC03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.53 | 45.0 | 3.79e-01 | 93.1% | 62.3% |
| 3dytA02 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.53 | 43.0 | 3.66e-01 | 94.1% | 94.2% |
| 4nqiD00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.53 | 47.0 | 3.62e-01 | 99.0% | 82.3% |
| 3hl1B01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.53 | 45.0 | 3.62e-01 | 97.0% | 95.4% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.53 | 42.0 | 4.18e-01 | 88.1% | 85.2% |
| 2y51A01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.53 | 40.0 | 2.90e-01 | 81.2% | 54.9% |
| 1gqeA01 | 1.20.58.410 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor | 0.53 | 40.0 | 3.87e-01 | 81.2% | 97.3% |
| 6jpaE00 | 1.20.140.150 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.52 | 43.0 | 3.70e-01 | 91.1% | 68.0% |
| 2d1lA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.52 | 44.0 | 3.45e-01 | 99.0% | 83.5% |
| 4jz6A01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.52 | 40.0 | 3.05e-01 | 84.2% | 36.8% |
| 2v5cA03 | 1.20.58.460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like | 0.50 | 42.0 | 3.89e-01 | 91.1% | 71.5% |
| 5kf6A01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.50 | 38.0 | 2.86e-01 | 80.2% | 40.4% |
ECOD (37)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3972253 | 5051.1.1.0 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like | 0.98 | 94.0 | 5.88e-01 | 98.0% | 23.3% |
| 4131767 | 5051.1.1.17 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Branch_AA_trans | 0.97 | 93.0 | 5.83e-01 | 99.0% | 23.0% |
| 3164177 | 5051.1.1.17 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Branch_AA_trans | 0.94 | 90.0 | 5.67e-01 | 100.0% | 23.7% |
| 3590283 | 5051.1.1.17 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Branch_AA_trans | 0.93 | 89.0 | 5.54e-01 | 100.0% | 24.0% |
| 4568028 | 5051.1.1.17 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Branch_AA_trans | 0.89 | 82.0 | 5.20e-01 | 97.0% | 23.0% |
| 4059292 | 5051.1.1.17 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Branch_AA_trans | 0.88 | 82.0 | 5.22e-01 | 100.0% | 23.9% |
| 3838379 | 601.53.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Flagellin glycosyltransferase Maf helical bundle domain › Flagellin glycosyltransferase Maf helical bundle domain | 0.67 | 51.0 | 4.96e-01 | 92.1% | 73.6% |
| 4991391 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.62 | 51.0 | 5.15e-01 | 91.1% | 89.0% |
| 3804319 | 102.1.1.172 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › PF31137 | 0.62 | 45.0 | 4.56e-01 | 88.1% | 77.0% |
| 5054069 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.60 | 51.0 | 4.65e-01 | 96.0% | 72.1% |
| 3855166 | 4177.1.1.12 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FAM92 | 0.59 | 48.0 | 3.63e-01 | 92.1% | 67.0% |
| 4239731 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.59 | 43.0 | 4.10e-01 | 77.2% | 71.7% |
| 4597483 | 5058.1.1.1 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1,MS_channel_1st | 0.58 | 48.0 | 4.59e-01 | 92.1% | 75.0% |
| 3802996 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.58 | 48.0 | 4.09e-01 | 92.1% | 59.4% |
| 5070526 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.58 | 44.0 | 4.33e-01 | 80.2% | 75.0% |
| 4953098 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.58 | 42.0 | 4.22e-01 | 83.2% | 76.0% |
| 3451722 | 3930.1.1.0 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase | 0.58 | 49.0 | 4.62e-01 | 93.1% | 80.0% |
| 3339772 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.58 | 48.0 | 4.29e-01 | 90.1% | 77.1% |
| 4161641 | 611.4.1.2 ↗ | alpha bundles › N-cbl like › PG0775 C-terminal domain-like › PG0775 C-terminal domain-like › Acyl-CoA_dh_C | 0.57 | 49.0 | 4.49e-01 | 96.0% | 94.0% |
| 4963259 | 3843.1.1.41 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › PF29293 | 0.57 | 45.0 | 4.78e-01 | 96.0% | 100.0% |
| 3978828 | 164.1.1.1 ↗ | alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › CM_2 | 0.56 | 45.0 | 3.92e-01 | 93.1% | 55.2% |
| 5012158 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.56 | 46.0 | 4.79e-01 | 92.1% | 95.8% |
| 3616476 | 4177.1.1.6 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3_WASP_bdg | 0.56 | 45.0 | 3.61e-01 | 90.1% | 80.5% |
| 5020613 | 1075.5.1.2 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ | 0.55 | 46.0 | 3.45e-01 | 92.1% | 89.0% |
| 3736699 | 605.4.1.4 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › DUF202 | 0.55 | 48.0 | 4.52e-01 | 99.0% | 84.8% |
| 3725890 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.55 | 45.0 | 4.23e-01 | 91.1% | 86.4% |
| 3216129 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.54 | 45.0 | 4.23e-01 | 91.1% | 75.2% |
| 3921427 | 180.1.1.7 ↗ | alpha bundles › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › PAP2_C | 0.54 | 44.0 | 3.39e-01 | 88.1% | 58.9% |
| 4017168 | 150.1.1.114 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › PF30036 | 0.54 | 42.0 | 3.71e-01 | 86.1% | 63.6% |
| 1487359 | 611.11.1.1 ↗ | alpha bundles › N-cbl like › Plasmodium host cell traversal protein SPECT1 › Plasmodium host cell traversal protein SPECT1 › SPECT1 | 0.53 | 47.0 | 3.97e-01 | 100.0% | 84.7% |
| 5049850 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.53 | 46.0 | 3.61e-01 | 100.0% | 88.7% |
| 5010597 | 5058.1.1.99 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › DUF373 | 0.53 | 45.0 | 4.17e-01 | 100.0% | 76.4% |
| 3828510 | 3291.1.1.3 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Ist1 | 0.52 | 45.0 | 3.76e-01 | 99.0% | 96.2% |
| 3440585 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.51 | 42.0 | 3.71e-01 | 88.1% | 80.0% |
| 5021415 | 3579.1.1.33 ↗ | extended segments › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › PsiE | 0.51 | 42.0 | 4.01e-01 | 93.1% | 76.0% |
| 4999379 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.50 | 41.0 | 3.56e-01 | 86.1% | 70.7% |
| 3177832 | 174.1.1.62 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › PF27705 | 0.50 | 42.0 | 3.66e-01 | 95.0% | 58.7% |
D2
medium
residues 1-121_173-252
Domain cluster:
representative
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05525.20 best | Branch_AA_trans | 142.9 | 2.10e-41 | 59.2% | 26.3% |
| PF05525.20 | Branch_AA_trans | 80.6 | 1.70e-22 | 42.3% | 17.9% |
CATH (15)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7b00A01 | 1.20.1740.10 | Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I | 0.73 | 66.0 | 5.03e-01 | 96.0% | 55.2% |
| 6nplA01 | 1.20.1740.10 | Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I | 0.72 | 65.0 | 4.87e-01 | 96.0% | 64.9% |
| 2zy9A03 | 1.10.357.20 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › SLC41 divalent cation transporters, integral membrane domain | 0.67 | 38.0 | 4.03e-01 | 99.5% | 61.5% |
| 2xq2A01 | 1.20.1730.10 | Mainly Alpha › Up-down Bundle › Sodium/glucose cotransporter › Sodium/glucose cotransporter | 0.67 | 61.0 | 4.46e-01 | 98.5% | 48.0% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.66 | 34.0 | 4.61e-01 | 94.0% | 93.6% |
| 4gkfA00 | 1.10.520.30 | Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › AF1862-like domain | 0.56 | 40.0 | 4.60e-01 | 94.5% | 99.3% |
| 5dvwA00 | 1.20.120.1160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.55 | 23.0 | 2.81e-01 | 81.6% | 55.3% |
| 3ezhA00 | 1.20.120.960 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase NarX, sensor domain | 0.53 | 30.0 | 3.98e-01 | 86.6% | 100.0% |
| 6n6qD00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.52 | 42.0 | 3.32e-01 | 85.1% | 75.7% |
| 6wbvA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.52 | 44.0 | 3.44e-01 | 89.6% | 88.3% |
| 2zopA00 | 1.10.520.30 | Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › AF1862-like domain | 0.52 | 29.0 | 3.84e-01 | 92.5% | 99.1% |
| 2jx0A00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.51 | 32.0 | 3.88e-01 | 87.6% | 94.7% |
| 7dl9A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.51 | 39.0 | 3.97e-01 | 96.5% | 80.9% |
| 4iu9B02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.51 | 42.0 | 4.27e-01 | 99.5% | 88.2% |
| 2onkC00 | 1.10.3720.10 | Mainly Alpha › Orthogonal Bundle › MetI-like fold › MetI-like | 0.50 | 40.0 | 3.69e-01 | 82.6% | 68.3% |
ECOD (46)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4131767 | 5051.1.1.17 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Branch_AA_trans | 0.99 | 97.0 | 7.18e-01 | 100.0% | 57.9% |
| 3972253 | 5051.1.1.0 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like | 0.98 | 94.0 | 7.01e-01 | 97.5% | 58.1% |
| 4033621 | 5051.1.1.17 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Branch_AA_trans | 0.97 | 89.0 | 6.62e-01 | 93.0% | 56.2% |
| 4059292 | 5051.1.1.17 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Branch_AA_trans | 0.97 | 93.0 | 6.86e-01 | 98.0% | 57.7% |
| 3164177 | 5051.1.1.17 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Branch_AA_trans | 0.96 | 91.0 | 6.73e-01 | 96.5% | 57.4% |
| 4031783 | 5051.1.1.17 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Branch_AA_trans | 0.95 | 91.0 | 6.73e-01 | 98.0% | 56.9% |
| 4568028 | 5051.1.1.17 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Branch_AA_trans | 0.94 | 90.0 | 6.73e-01 | 98.0% | 58.4% |
| 4389073 | 5051.1.1.17 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Branch_AA_trans | 0.94 | 91.0 | 6.78e-01 | 98.5% | 57.2% |
| 5078049 | 5051.1.1.2 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › AA_permease | 0.76 | 72.0 | 5.51e-01 | 99.5% | 57.9% |
| 3783708 | 5051.1.1.6 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Aa_trans | 0.75 | 71.0 | 5.57e-01 | 99.0% | 63.4% |
| 4446544 | 1079.1.1.8 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › LysE | 0.73 | 58.0 | 5.98e-01 | 98.0% | 86.4% |
| 5013624 | 5051.1.1.12 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Trp_Tyr_perm | 0.72 | 68.0 | 5.60e-01 | 100.0% | 68.2% |
| 3996496 | 5051.1.1.6 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Aa_trans | 0.72 | 67.0 | 5.51e-01 | 98.5% | 63.2% |
| 3943261 | 5050.1.1.53 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MarC | 0.70 | 61.0 | 5.95e-01 | 97.5% | 84.7% |
| 3694901 | 3921.1.1.3 ↗ | alpha complex topology › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › GDT1 | 0.69 | 50.0 | 5.33e-01 | 98.5% | 83.3% |
| 4942452 | 5050.1.1.53 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MarC | 0.68 | 55.0 | 5.47e-01 | 98.0% | 82.0% |
| 3964144 | 1079.1.1.9 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Cad | 0.67 | 54.0 | 5.37e-01 | 97.5% | 80.9% |
| 5064419 | 5051.1.1.9 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Transp_cyt_pur | 0.67 | 61.0 | 4.83e-01 | 99.0% | 57.1% |
| 5046582 | 3921.1.1.3 ↗ | alpha complex topology › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › GDT1 | 0.67 | 51.0 | 5.34e-01 | 98.5% | 85.4% |
| 3942162 | 1079.1.1.8 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › LysE | 0.67 | 53.0 | 5.44e-01 | 96.5% | 86.8% |
| 4982608 | 1079.1.1.0 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA | 0.66 | 59.0 | 5.77e-01 | 99.5% | 88.4% |
| 4169514 | 5050.1.1.54 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Mntp | 0.66 | 50.0 | 5.26e-01 | 98.5% | 85.4% |
| 4561356 | 1079.1.1.14 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › MarC | 0.66 | 57.0 | 5.60e-01 | 98.0% | 86.2% |
| 5048853 | 1079.1.1.8 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › LysE | 0.64 | 55.0 | 5.34e-01 | 98.0% | 83.1% |
| 4104623 | 1079.1.1.8 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › LysE | 0.64 | 54.0 | 5.47e-01 | 97.0% | 89.5% |
| 3278851 | 3538.1.1.4 ↗ | extended segments › MerF › MerF › MerF › LysE | 0.64 | 53.0 | 5.31e-01 | 96.5% | 84.6% |
| 5070330 | 1079.1.1.0 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA | 0.64 | 57.0 | 5.49e-01 | 97.0% | 84.8% |
| 5018995 | 1079.1.1.5 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › DsbD_2 | 0.64 | 57.0 | 5.51e-01 | 97.5% | 86.4% |
| 3285229 | 1079.1.1.8 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › LysE | 0.63 | 48.0 | 5.02e-01 | 88.6% | 84.9% |
| 3667987 | 1079.1.1.0 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA | 0.63 | 50.0 | 5.07e-01 | 98.5% | 83.0% |
| 4465482 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.63 | 37.0 | 3.63e-01 | 97.5% | 53.0% |
| 5003109 | 1079.1.1.1 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › DsbD | 0.62 | 56.0 | 5.42e-01 | 98.0% | 85.8% |
| 4958586 | 1079.1.1.5 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › DsbD_2 | 0.61 | 55.0 | 5.29e-01 | 99.0% | 85.3% |
| 4950461 | 1079.1.1.5 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › DsbD_2 | 0.61 | 51.0 | 5.11e-01 | 99.0% | 86.7% |
| 3387961 | 1079.1.1.1 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › DsbD | 0.60 | 52.0 | 4.72e-01 | 97.5% | 69.8% |
| 3955855 | 1079.1.1.0 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA | 0.60 | 53.0 | 5.08e-01 | 98.5% | 82.6% |
| 4989287 | 1079.1.1.0 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA | 0.60 | 52.0 | 5.07e-01 | 96.0% | 85.5% |
| 3204822 | 5050.1.1.49 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › NicO | 0.59 | 55.0 | 4.62e-01 | 100.0% | 68.1% |
| 5061899 | 1079.1.1.1 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › DsbD | 0.59 | 54.0 | 5.21e-01 | 98.5% | 86.7% |
| 4981050 | 1079.1.1.5 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › DsbD_2 | 0.59 | 55.0 | 5.22e-01 | 99.0% | 87.7% |
| 4958052 | 1079.1.1.5 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › DsbD_2 | 0.57 | 50.0 | 4.90e-01 | 98.0% | 86.4% |
| 3950284 | 1079.1.1.7 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › SfLAP | 0.57 | 50.0 | 5.20e-01 | 95.5% | 100.0% |
| 4016768 | 180.1.1.1 ↗ | alpha bundles › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › PAP2 | 0.51 | 38.0 | 3.13e-01 | 76.1% | 70.5% |
| 4517020 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.51 | 23.0 | 1.86e-01 | 82.6% | 19.5% |
| 3637309 | 4323.1.1.0 ↗ | alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C | 0.51 | 35.0 | 3.67e-01 | 76.1% | 75.3% |
| 4009921 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.50 | 42.0 | 3.83e-01 | 100.0% | 66.4% |
D3
medium
residues 122-172_253-331
Domain cluster:
representative
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05525.20 best | Branch_AA_trans | 81.2 | 1.10e-22 | 63.8% | 18.6% |
| PF05525.20 | Branch_AA_trans | 42.4 | 6.70e-11 | 42.3% | 11.9% |
CATH (49)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2bdeA03 | 1.20.58.1160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 36.0 | 4.57e-01 | 70.0% | 83.1% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.69 | 31.0 | 3.30e-01 | 70.0% | 46.0% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.68 | 39.0 | 4.60e-01 | 85.4% | 84.7% |
| 7sgrA02 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.65 | 42.0 | 3.12e-01 | 72.3% | 27.1% |
| 3anwB00 | 1.20.58.2050 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 35.0 | 3.24e-01 | 73.8% | 41.4% |
| 4rngC00 | 1.20.1280.290 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.64 | 35.0 | 4.24e-01 | 75.4% | 81.9% |
| 5figA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.64 | 32.0 | 3.56e-01 | 82.3% | 59.0% |
| 2wdqA03 | 1.20.58.100 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain | 0.64 | 38.0 | 3.97e-01 | 84.6% | 64.1% |
| 1gqeA01 | 1.20.58.410 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor | 0.63 | 45.0 | 4.76e-01 | 83.1% | 84.1% |
| 3i9yA00 | 1.20.58.920 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 45.0 | 3.69e-01 | 73.8% | 66.4% |
| 2q12A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.62 | 47.0 | 3.75e-01 | 78.5% | 63.6% |
| 4fzsA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.61 | 47.0 | 4.01e-01 | 81.5% | 81.3% |
| 2qvaA01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.60 | 34.0 | 3.46e-01 | 70.0% | 53.5% |
| 3u4qA02 | 1.10.274.50 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › | 0.60 | 40.0 | 3.79e-01 | 85.4% | 57.3% |
| 1x04A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.60 | 45.0 | 3.91e-01 | 78.5% | 72.0% |
| 1uruA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.60 | 46.0 | 3.90e-01 | 80.0% | 72.7% |
| 5zw7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.60 | 42.0 | 4.04e-01 | 72.3% | 94.7% |
| 1t72A02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.59 | 38.0 | 4.35e-01 | 76.9% | 86.7% |
| 2ficB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.59 | 45.0 | 3.88e-01 | 80.0% | 74.6% |
| 1sumB02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.58 | 38.0 | 3.99e-01 | 77.7% | 72.9% |
| 3gi7A00 | 1.20.1270.180 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.58 | 35.0 | 3.86e-01 | 100.0% | 74.8% |
| 4lwsA00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.58 | 40.0 | 4.53e-01 | 73.1% | 93.0% |
| 2vs0A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.57 | 36.0 | 4.41e-01 | 70.0% | 100.0% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.57 | 41.0 | 4.35e-01 | 89.2% | 86.4% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.57 | 42.0 | 4.71e-01 | 76.9% | 98.0% |
| 3zdqA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.56 | 38.0 | 2.82e-01 | 71.5% | 27.0% |
| 7p3rA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.56 | 43.0 | 3.24e-01 | 81.5% | 86.2% |
| 6xkyA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.56 | 39.0 | 3.47e-01 | 72.3% | 94.1% |
| 2rd0B00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.56 | 38.0 | 3.76e-01 | 70.0% | 90.6% |
| 6h2dS01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.56 | 42.0 | 3.53e-01 | 79.2% | 73.5% |
| 2xheA03 | 3.90.830.10 | Alpha Beta › Alpha-Beta Complex › Syntaxin Binding Protein 1; Chain A, domain 2 › Sec1/Munc18 (SM) protein, domain 3a | 0.55 | 38.0 | 3.96e-01 | 70.0% | 95.9% |
| 4ioeA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.55 | 35.0 | 4.19e-01 | 70.0% | 96.6% |
| 3na7A00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.55 | 38.0 | 3.13e-01 | 73.8% | 39.2% |
| 2d1lA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.54 | 43.0 | 3.46e-01 | 83.8% | 72.3% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 40.0 | 3.64e-01 | 76.9% | 67.6% |
| 1wdzA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.54 | 44.0 | 3.61e-01 | 86.2% | 77.9% |
| 6vddA02 | 1.20.1060.10 | Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 | 0.54 | 42.0 | 4.48e-01 | 85.4% | 96.5% |
| 1kmiZ02 | 1.10.287.500 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.53 | 37.0 | 3.70e-01 | 72.3% | 69.4% |
| 6xj1A01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.53 | 40.0 | 3.27e-01 | 80.0% | 77.1% |
| 1zk8B02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 41.0 | 4.08e-01 | 99.2% | 80.3% |
| 1l8dA00 | 1.10.287.510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.52 | 37.0 | 4.12e-01 | 73.8% | 92.2% |
| 3qnmA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.52 | 29.0 | 3.33e-01 | 85.4% | 75.6% |
| 2yhsA01 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.52 | 33.0 | 3.76e-01 | 95.4% | 84.5% |
| 2zw3A00 | 1.20.1440.80 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Gap junction channel protein cysteine-rich domain | 0.51 | 41.0 | 3.61e-01 | 86.9% | 59.7% |
| 3c07B00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 39.0 | 3.34e-01 | 80.8% | 65.4% |
| 3vkgA12 | 1.10.287.2610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.51 | 37.0 | 3.14e-01 | 75.4% | 92.1% |
| 7aalA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.51 | 39.0 | 3.08e-01 | 80.0% | 73.3% |
| 3k29A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.51 | 35.0 | 3.32e-01 | 71.5% | 80.7% |
| 4bwcA02 | 1.10.439.20 | Mainly Alpha › Orthogonal Bundle › Penicillin Amidohydrolase; domain 1 › Phospholipase B-like, domain 2 | 0.51 | 36.0 | 3.78e-01 | 80.0% | 80.3% |
ECOD (59)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4131767 | 5051.1.1.17 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Branch_AA_trans | 0.97 | 94.0 | 6.21e-01 | 100.0% | 48.3% |
| 4389073 | 5051.1.1.17 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Branch_AA_trans | 0.93 | 90.0 | 5.99e-01 | 100.0% | 48.2% |
| 4033621 | 5051.1.1.17 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Branch_AA_trans | 0.90 | 87.0 | 5.80e-01 | 100.0% | 49.2% |
| 5013624 | 5051.1.1.12 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Trp_Tyr_perm | 0.85 | 81.0 | 5.74e-01 | 100.0% | 56.0% |
| 3165861 | 5051.1.1.1 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › SNF | 0.82 | 76.0 | 5.12e-01 | 100.0% | 47.6% |
| 3947843 | 5051.1.1.2 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › AA_permease | 0.80 | 75.0 | 5.08e-01 | 100.0% | 50.9% |
| 4008271 | 5051.1.1.2 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › AA_permease | 0.80 | 75.0 | 5.09e-01 | 100.0% | 52.1% |
| 5054652 | 5051.1.1.0 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like | 0.76 | 70.0 | 5.03e-01 | 100.0% | 52.3% |
| 4182984 | 6155.1.1.0 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter | 0.67 | 45.0 | 4.85e-01 | 86.9% | 80.9% |
| 3505596 | 1075.4.1.9 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_tran+ABC_membrane | 0.66 | 40.0 | 2.75e-01 | 72.3% | 18.3% |
| 3638435 | 1073.1.1.14 ↗ | alpha arrays › Mitochondrial calcium uniporter (MCU) › Mitochondrial calcium uniporter (MCU) › Mitochondrial calcium uniporter (MCU) › LMBR1 | 0.65 | 45.0 | 4.80e-01 | 70.8% | 88.6% |
| 3923560 | 3755.3.1.464 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Dcst2 | 0.63 | 43.0 | 4.13e-01 | 73.1% | 62.1% |
| 3795373 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.62 | 49.0 | 3.95e-01 | 83.1% | 74.6% |
| 3305910 | 604.3.1.37 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › DUF2921 | 0.60 | 42.0 | 4.51e-01 | 75.4% | 82.6% |
| 3635376 | 3755.3.1.298 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › ING | 0.60 | 41.0 | 4.12e-01 | 72.3% | 68.1% |
| 3937673 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.59 | 49.0 | 3.61e-01 | 86.9% | 69.1% |
| 3299091 | 3567.1.1.126 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › PF29520 | 0.59 | 49.0 | 4.85e-01 | 87.7% | 87.4% |
| 341832 | 4177.1.1.8 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3 | 0.59 | 47.0 | 3.67e-01 | 83.1% | 61.9% |
| 3927148 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.58 | 40.0 | 3.38e-01 | 71.5% | 77.7% |
| 4339446 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.57 | 42.0 | 3.20e-01 | 75.4% | 63.0% |
| 4681331 | 3921.1.1.0 ↗ | alpha complex topology › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D | 0.57 | 53.0 | 4.73e-01 | 100.0% | 92.8% |
| 5023516 | 3922.1.1.269 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Rad50_zn_hook | 0.56 | 41.0 | 3.36e-01 | 75.4% | 70.6% |
| 4935333 | 3755.3.1.637 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 | 0.56 | 40.0 | 3.80e-01 | 72.3% | 62.0% |
| 5081955 | 3834.1.1.25 ↗ | alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain › DUF7121 | 0.56 | 40.0 | 3.10e-01 | 72.3% | 93.0% |
| 4944758 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.56 | 41.0 | 3.00e-01 | 75.4% | 87.9% |
| 3996264 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.56 | 39.0 | 3.61e-01 | 72.3% | 54.7% |
| 3547040 | 376.1.3.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger | 0.56 | 39.0 | 3.58e-01 | 72.3% | 90.0% |
| 4021653 | 1075.4.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold | 0.55 | 41.0 | 3.10e-01 | 76.9% | 74.0% |
| 3235287 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.55 | 39.0 | 3.05e-01 | 73.1% | 34.6% |
| 3365701 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.55 | 38.0 | 4.11e-01 | 72.3% | 82.7% |
| 5029397 | 1079.1.1.7 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › SfLAP | 0.55 | 50.0 | 4.22e-01 | 100.0% | 61.4% |
| 3273941 | 4177.1.1.8 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3 | 0.55 | 45.0 | 3.71e-01 | 86.9% | 75.7% |
| 4958586 | 1079.1.1.5 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › DsbD_2 | 0.55 | 50.0 | 4.15e-01 | 100.0% | 60.4% |
| 3611077 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.55 | 41.0 | 3.69e-01 | 80.0% | 88.1% |
| 3600956 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.54 | 42.0 | 3.69e-01 | 80.8% | 80.0% |
| 3239816 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.54 | 38.0 | 3.29e-01 | 72.3% | 46.5% |
| 3215082 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.54 | 36.0 | 3.59e-01 | 71.5% | 65.2% |
| 4295915 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.54 | 38.0 | 3.81e-01 | 73.1% | 71.5% |
| 3204822 | 5050.1.1.49 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › NicO | 0.54 | 48.0 | 3.61e-01 | 100.0% | 46.6% |
| 3610234 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.53 | 37.0 | 4.00e-01 | 76.2% | 84.5% |
| 4021337 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.53 | 44.0 | 3.51e-01 | 87.7% | 78.8% |
| 3948661 | 3860.1.1.167 ↗ | alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm › MscS_porin | 0.53 | 41.0 | 2.95e-01 | 82.3% | 40.0% |
| 4121246 | 4177.2.1.4 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain › ATG17_like | 0.53 | 41.0 | 3.20e-01 | 81.5% | 65.3% |
| 4424383 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.53 | 37.0 | 3.38e-01 | 71.5% | 56.6% |
| 3763454 | 5086.1.1.87 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING | 0.53 | 37.0 | 3.89e-01 | 71.5% | 77.5% |
| 5051910 | 1075.3.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 | 0.53 | 47.0 | 3.49e-01 | 99.2% | 57.7% |
| 3369676 | 603.2.1.13 ↗ | alpha bundles › STAT-like › STAT › STAT › NET2A_C | 0.53 | 39.0 | 3.51e-01 | 76.9% | 80.6% |
| 4025973 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.53 | 38.0 | 2.90e-01 | 74.6% | 91.4% |
| 4418753 | 3755.3.1.363 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › T1-F | 0.52 | 43.0 | 3.34e-01 | 87.7% | 97.5% |
| 3393646 | 102.1.3.0 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › PAP/OAS1 substrate-binding domain | 0.52 | 32.0 | 3.36e-01 | 93.1% | 65.0% |
| 3984201 | 192.2.1.73 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › MscS_porin | 0.52 | 41.0 | 2.79e-01 | 83.1% | 72.7% |
| 3498458 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.51 | 37.0 | 3.40e-01 | 72.3% | 78.8% |
| 3921243 | 2004.1.1.433 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23 | 0.51 | 37.0 | 2.32e-01 | 73.8% | 15.1% |
| 3496300 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.51 | 40.0 | 3.75e-01 | 84.6% | 67.3% |
| 3593427 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.51 | 38.0 | 3.56e-01 | 76.2% | 71.6% |
| 4163282 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.51 | 39.0 | 3.49e-01 | 80.8% | 63.8% |
| 3930842 | 4177.1.1.10 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › GMIP-like_FCH | 0.51 | 40.0 | 3.07e-01 | 83.8% | 72.5% |
| 5013116 | 2004.1.1.5 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran | 0.50 | 38.0 | 2.48e-01 | 77.7% | 50.8% |
| 3682214 | 109.4.1.1414 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_TTI1_C | 0.50 | 44.0 | 3.07e-01 | 96.2% | 43.0% |