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CAKLQF020000009.1__CAH1083285.1__SAMEA5780031_01917__00012

Bact-Vir

CAKLQF020000009.1__CAH1083285.1__SAMEA5780031_01917__00012

Identity

Kingdom:
phage

Quality

89.1 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 56-117_233-324
PDB
CATH (11)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4exrA01 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.68 33.0 4.49e-01 88.3% 88.9%
4exrA02 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.66 31.0 4.42e-01 88.3% 95.8%
3u1wA02 3.10.450.360 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.65 30.0 4.33e-01 79.2% 98.5%
2rqlA00 3.30.160.100 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Ribosome hibernation promotion factor-like 0.56 32.0 3.86e-01 93.5% 87.4%
2bbuA00 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.56 27.0 2.79e-01 96.8% 42.9%
4g2sA00 2.60.200.20 Mainly Beta › Sandwich › Tumour Suppressor Smad4 › 0.55 31.0 3.61e-01 89.6% 78.3%
4bhrA00 3.30.1300.70 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › 0.53 29.0 3.74e-01 92.9% 98.8%
6grrA02 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.52 32.0 3.86e-01 91.6% 94.1%
3kstA00 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.51 41.0 3.36e-01 85.7% 71.5%
1e8oA00 3.30.720.10 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › Signal recognition particle alu RNA binding heterodimer, srp9/1 0.51 24.0 3.39e-01 81.2% 93.2%
4akrA02 3.90.1150.210 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › F-actin capping protein, beta subunit 0.50 32.0 3.32e-01 91.6% 66.7%
ECOD (9)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3988729 4097.1.1.0 a+b two layers › Lp2179-like › Lp2179-like › Lp2179-like 0.64 26.0 3.33e-01 76.6% 61.1%
3964304 884.1.1.1 a+b two layers › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain › CobW_C 0.64 24.0 3.09e-01 77.9% 55.7%
3590768 884.1.1.1 a+b two layers › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain › CobW_C 0.63 25.0 3.20e-01 78.6% 58.9%
3972879 330.2.1.1 a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) › Ribosomal_S30AE 0.58 33.0 3.93e-01 93.5% 83.0%
4033429 243.3.1.3 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › PepSY 0.58 30.0 3.96e-01 73.4% 93.8%
4464688 884.1.1.1 a+b two layers › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain › CobW_C 0.57 23.0 2.97e-01 80.5% 61.7%
3820070 5.1.2.62 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 5-bladed › FBA_1 0.54 35.0 3.14e-01 92.2% 44.4%
3841986 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.51 37.0 3.02e-01 75.3% 51.7%
3259927 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.51 40.0 3.25e-01 84.4% 59.7%
D2 medium residues 1-51_121-162
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF03929.22 best PepSY_TM 31.7 2.10e-07 49.5% 13.2%
PF03929.22 PepSY_TM 42.2 1.30e-10 49.5% 13.2%
CATH (51)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3a98A02 1.20.1270.350 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Dedicator of cytokinesis N-terminal subdomain 0.67 40.0 4.16e-01 79.6% 63.2%
1zoyD00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.65 40.0 3.91e-01 100.0% 55.9%
3fppA03 6.10.140.1990 Special › Helix non-globular › Helix Hairpins › 0.64 46.0 4.76e-01 90.3% 79.5%
3rguB00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.63 40.0 4.20e-01 80.6% 69.0%
4fjvA02 1.20.1300.20 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Peptidase C65 Otubain, subdomain 2 0.63 40.0 3.51e-01 90.3% 41.0%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 42.0 4.41e-01 89.2% 77.8%
1x04A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.62 46.0 3.63e-01 86.0% 37.0%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.62 47.0 4.56e-01 90.3% 71.0%
1u00A02 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.62 38.0 3.85e-01 81.7% 59.4%
1urfA00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.62 41.0 4.34e-01 89.2% 77.8%
4e6nA02 6.10.140.1010 Special › Helix non-globular › Helix Hairpins › 0.62 42.0 4.88e-01 91.4% 100.0%
3lnnB03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.62 41.0 4.63e-01 80.6% 94.0%
1sg2A00 3.30.910.20 Alpha Beta › 2-Layer Sandwich › Protein Binding, DinI Protein; Chain A › Skp domain 0.61 44.0 3.85e-01 84.9% 49.6%
5ha6B00 1.10.287.210 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.61 46.0 4.85e-01 93.5% 94.9%
1wp7A00 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.61 39.0 4.64e-01 76.3% 95.3%
1wncB00 1.20.5.300 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.61 44.0 4.67e-01 89.2% 88.9%
3qo8A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.60 47.0 4.49e-01 91.4% 72.6%
4iggA01 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.60 39.0 4.53e-01 78.5% 92.5%
3o6xA02 1.20.120.1560 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.60 47.0 4.09e-01 86.0% 66.9%
4iggB02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.59 40.0 3.66e-01 79.6% 52.9%
1skvA00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.59 39.0 4.55e-01 76.3% 98.4%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.59 47.0 4.48e-01 90.3% 72.3%
1y1uA01 1.20.1050.20 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain 0.59 52.0 4.13e-01 100.0% 87.2%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.59 40.0 4.11e-01 86.0% 74.7%
3hr0B01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.58 43.0 4.62e-01 83.9% 92.4%
1rq0A01 6.10.140.160 Special › Helix non-globular › Helix Hairpins › 0.58 40.0 4.15e-01 79.6% 79.5%
4cgkA01 6.10.250.3150 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.58 48.0 3.76e-01 93.5% 72.4%
6q45G01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.58 47.0 4.12e-01 90.3% 80.1%
2p0tA02 1.10.60.30 Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › PSPTO4464-like domains 0.58 29.0 3.31e-01 71.0% 62.5%
3rrkA02 1.20.1460.20 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › 0.58 51.0 4.31e-01 97.8% 60.0%
3vkgA12 1.10.287.2610 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.57 46.0 3.57e-01 89.2% 38.1%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.57 41.0 4.34e-01 89.2% 90.9%
8ek4A01 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.57 44.0 3.95e-01 83.9% 59.4%
2v0xA01 1.10.287.3160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.56 45.0 3.74e-01 90.3% 48.2%
6zhiB02 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.56 35.0 3.66e-01 98.9% 67.5%
2dw4A03 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.56 46.0 4.54e-01 89.2% 96.0%
4dylA02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.56 48.0 4.85e-01 97.8% 95.7%
2gl2B00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.55 47.0 4.52e-01 96.8% 89.9%
4nsmA00 6.10.250.2770 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.55 40.0 4.44e-01 77.4% 100.0%
3h3mA00 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.55 35.0 3.57e-01 83.9% 65.2%
3a7mA01 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.55 35.0 3.40e-01 78.5% 55.5%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.54 43.0 3.76e-01 90.3% 55.1%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.54 37.0 3.98e-01 90.3% 88.0%
1h7cA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 47.0 4.58e-01 98.9% 98.1%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.53 43.0 4.35e-01 90.3% 91.1%
2xokP00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.53 38.0 4.09e-01 88.2% 94.6%
3vprA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.53 39.0 3.40e-01 87.1% 49.7%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.53 43.0 4.03e-01 89.2% 89.7%
3teqB00 1.10.287.3550 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.53 45.0 4.47e-01 97.8% 96.0%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.51 42.0 4.11e-01 88.2% 95.0%
3iqcA00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.50 42.0 3.92e-01 91.4% 92.4%
ECOD (39)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3618142 3939.1.1.0 alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain 0.71 41.0 4.12e-01 79.6% 56.8%
3973899 5086.1.1.92 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE 0.69 48.0 4.16e-01 84.9% 46.9%
3518039 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.67 54.0 5.17e-01 94.6% 76.2%
3961148 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.64 51.0 4.69e-01 84.9% 92.5%
3175421 3922.1.1.312 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › PF30554 0.61 47.0 4.07e-01 81.7% 86.4%
4096686 632.7.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.60 37.0 3.92e-01 93.5% 68.2%
3494616 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.60 45.0 4.67e-01 80.6% 85.9%
4259224 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.60 47.0 3.97e-01 90.3% 50.3%
4774272 192.1.1.1 alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › MCPsignal 0.60 44.0 4.32e-01 90.3% 72.3%
3609437 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.59 49.0 4.37e-01 93.5% 63.0%
5049284 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.59 49.0 4.57e-01 93.5% 90.0%
3943069 3291.1.1.136 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PF27688 0.59 46.0 4.12e-01 86.0% 71.1%
3704105 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.58 49.0 4.15e-01 93.5% 70.6%
3574626 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.58 46.0 4.07e-01 87.1% 61.4%
3468090 5086.1.1.87 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING 0.58 45.0 4.23e-01 86.0% 67.8%
3182497 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.57 50.0 3.28e-01 98.9% 34.2%
3740547 5086.1.1.87 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING 0.56 42.0 3.99e-01 86.0% 67.3%
3229124 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.56 48.0 4.13e-01 92.5% 94.5%
5060432 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.56 47.0 4.25e-01 93.5% 76.2%
3978264 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.56 42.0 3.64e-01 83.9% 50.7%
4983461 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.55 47.0 4.40e-01 97.8% 89.2%
3386594 3291.1.1.197 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › MCPsignal 0.55 44.0 4.33e-01 90.3% 84.8%
3719904 148.1.3.13 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_9 0.55 44.0 2.97e-01 91.4% 21.9%
3681508 3922.1.1.194 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › SPX 0.55 47.0 4.66e-01 97.8% 95.0%
3880637 3755.3.1.465 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A 0.55 46.0 4.06e-01 93.5% 64.3%
3733140 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.55 43.0 3.73e-01 87.1% 86.5%
3615972 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.55 45.0 3.64e-01 90.3% 47.0%
5079633 7094.1.1.4 alpha bundles › Paddle domain of mitochondrial dynamin › Paddle domain of mitochondrial dynamin › Paddle domain of mitochondrial dynamin › PF27273 0.55 41.0 4.24e-01 90.3% 85.9%
4974533 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.55 49.0 4.33e-01 100.0% 71.1%
3928004 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.54 35.0 3.55e-01 98.9% 66.7%
3804036 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.54 45.0 4.24e-01 94.6% 89.6%
3782183 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.53 46.0 2.98e-01 97.8% 19.6%
3743940 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.53 47.0 3.93e-01 97.8% 86.3%
4938271 605.6.1.0 alpha duplicates or obligate multimers › ROP-like › HP1531-like › HP1531-like 0.53 43.0 4.38e-01 90.3% 92.2%
3935140 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.53 45.0 3.70e-01 97.8% 85.0%
3628940 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.53 45.0 4.33e-01 97.8% 95.5%
3390311 604.7.1.0 alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A 0.53 45.0 4.34e-01 97.8% 95.5%
4116038 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.52 43.0 3.72e-01 93.5% 58.7%
3837413 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.52 46.0 3.91e-01 96.8% 98.7%
D3 medium residues 163-232_325-366
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03929.22 best PepSY_TM 41.9 1.60e-10 63.4% 14.9%
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1skvA00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.74 41.0 5.34e-01 89.3% 95.3%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.72 39.0 4.04e-01 89.3% 57.0%
8anqA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.71 37.0 2.91e-01 88.4% 25.9%
1h6gA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.69 39.0 3.87e-01 88.4% 52.1%
3vkgA12 1.10.287.2610 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 39.0 3.14e-01 89.3% 29.8%
3vkgA02 1.20.140.100 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain 0.66 39.0 3.58e-01 84.8% 44.2%
3lnnB03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.66 39.0 4.94e-01 88.4% 100.0%
2gl2B00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.65 42.0 4.26e-01 90.2% 66.1%
1u5pA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 37.0 3.83e-01 89.3% 58.3%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.64 39.0 4.38e-01 94.6% 78.8%
1a7eA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.63 34.0 3.36e-01 100.0% 49.2%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.61 44.0 4.61e-01 95.5% 81.4%
6gy8A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.55 42.0 2.99e-01 79.5% 96.4%
4xpwA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.54 36.0 3.49e-01 95.5% 59.5%
2etdA00 1.20.1440.20 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain 0.54 45.0 4.16e-01 89.3% 81.6%
2q00B00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.53 42.0 4.06e-01 97.3% 76.2%
2l6hA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.52 36.0 3.26e-01 70.5% 87.0%
1x04A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.52 39.0 3.27e-01 80.4% 50.0%
1wtyA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.51 36.0 3.59e-01 93.8% 70.7%
3o10C00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.51 39.0 3.67e-01 100.0% 67.6%
3zc0D00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.50 42.0 3.48e-01 95.5% 52.9%
ECOD (17)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3971188 5001.1.1.248 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › PepSY_TM 0.76 71.0 6.37e-01 100.0% 78.0%
3565133 3755.3.1.44 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › JMY 0.70 40.0 3.90e-01 89.3% 51.7%
2698234 192.24.1.1 alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain › RPC3_helical 0.70 48.0 4.94e-01 89.3% 73.1%
3421089 3291.1.1.99 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › UPF0114 0.62 42.0 3.67e-01 89.3% 48.1%
3595675 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.62 38.0 3.00e-01 89.3% 30.2%
3251434 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.61 38.0 3.26e-01 89.3% 39.4%
3297061 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.61 39.0 3.91e-01 91.1% 62.6%
4338603 601.14.1.1 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.57 33.0 3.23e-01 86.6% 49.6%
3634705 601.1.2.50 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › GIT1_C 0.53 38.0 3.61e-01 96.4% 60.7%
3261777 4177.1.1.8 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3 0.53 39.0 3.18e-01 78.6% 56.9%
3673192 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.51 38.0 3.25e-01 99.1% 50.0%
3262123 331.1.1.12 a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like › DUF155 0.51 41.0 3.43e-01 89.3% 87.6%
54352 133.2.1.0 alpha bundles › DH domain-like › Methenyltetrahydrofolate cyclohydrolase-like › Methenyltetrahydrofolate cyclohydrolase-like 0.51 47.0 3.84e-01 100.0% 80.8%
5057329 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.51 43.0 3.91e-01 89.3% 83.4%
4002015 4177.1.1.3 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Arfaptin 0.51 37.0 3.02e-01 77.7% 56.0%
4321938 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.50 41.0 3.57e-01 89.3% 58.2%
3225163 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.50 41.0 3.93e-01 98.2% 75.4%
D4 medium residues 367-507
PDB
Domain cluster: representative
CATH (40)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.70 41.0 5.10e-01 100.0% 92.2%
8e9gK01 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 40.0 4.89e-01 77.3% 92.3%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.63 37.0 4.14e-01 73.8% 72.6%
3dbyL00 1.20.1260.120 Mainly Alpha › Up-down Bundle › Ferritin › Protein of unknown function DUF2935 0.62 48.0 3.91e-01 86.5% 43.5%
3g67A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.62 39.0 3.36e-01 100.0% 41.3%
3r2kA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.62 49.0 4.77e-01 96.5% 76.6%
7dl9B02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.61 50.0 4.40e-01 85.8% 92.1%
3i9wA00 1.20.58.920 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 40.0 3.21e-01 74.5% 34.1%
1b5lA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.60 40.0 3.93e-01 80.9% 61.8%
3rkoG00 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.60 38.0 4.33e-01 73.0% 88.0%
1yuzB01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.60 44.0 4.52e-01 92.2% 79.7%
1tjlA00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.60 43.0 4.27e-01 84.4% 71.0%
1otkA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.60 50.0 4.15e-01 94.3% 52.0%
3iq1B00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.59 46.0 4.43e-01 90.1% 72.3%
3qhbA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.59 49.0 4.51e-01 87.9% 74.3%
5ffdA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.59 44.0 4.52e-01 90.1% 81.8%
7w5gA01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.58 43.0 3.17e-01 75.9% 58.0%
3hiuD00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.58 49.0 4.81e-01 91.5% 84.2%
5zw7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.58 49.0 4.80e-01 90.8% 95.4%
3kmiA00 1.20.120.940 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Putative aromatic acid exporter, C-terminal domain 0.57 41.0 3.84e-01 73.0% 93.6%
2i0mA02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.57 38.0 4.36e-01 78.7% 92.1%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.57 39.0 4.40e-01 83.7% 90.7%
8hk0B03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.57 49.0 4.94e-01 92.2% 96.4%
1t98A02 1.20.58.590 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain 0.55 47.0 4.50e-01 90.8% 100.0%
3zc0D00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 42.0 3.82e-01 78.7% 69.5%
1j30A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.55 40.0 4.09e-01 75.2% 90.1%
1r2jA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.55 46.0 4.59e-01 90.1% 91.7%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.54 43.0 4.61e-01 90.1% 100.0%
1t72A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.54 39.0 4.23e-01 79.4% 88.9%
1qkrB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.54 44.0 4.08e-01 92.2% 68.3%
3ddeB00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.54 46.0 3.91e-01 92.9% 57.6%
6dlzA01 1.20.140.150 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.54 45.0 4.13e-01 89.4% 96.7%
5k3hB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.53 43.0 4.40e-01 85.1% 95.5%
7p3rA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.53 44.0 3.33e-01 87.2% 85.8%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.53 39.0 4.20e-01 82.3% 95.6%
2qf9A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.52 43.0 4.23e-01 89.4% 83.3%
1u89A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.52 45.0 4.53e-01 97.9% 95.7%
1jm6B02 1.20.140.20 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain 0.51 40.0 3.95e-01 90.1% 77.1%
1kpgD00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 37.0 2.93e-01 73.8% 93.3%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.50 37.0 3.52e-01 77.3% 76.3%
ECOD (57)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3973604 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.94 82.0 6.02e-01 90.1% 40.0%
3228799 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.71 63.0 5.69e-01 97.2% 76.4%
3388176 5059.1.1.2 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Multi_Drug_Res 0.70 46.0 5.10e-01 75.9% 84.5%
3934353 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.69 63.0 5.06e-01 100.0% 58.9%
3737954 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.67 41.0 4.03e-01 84.4% 56.7%
4874447 5059.1.1.2 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Multi_Drug_Res 0.67 45.0 5.17e-01 75.9% 92.2%
3836944 3615.1.1.54 alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › DUF3611 0.67 58.0 5.90e-01 93.6% 100.0%
3593555 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.65 45.0 4.04e-01 78.7% 51.6%
3938965 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.65 58.0 4.82e-01 97.2% 64.5%
3336589 5050.1.1.8 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 0.63 52.0 4.44e-01 85.8% 83.2%
5013764 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.63 50.0 4.46e-01 87.2% 59.5%
4987192 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.62 40.0 4.24e-01 75.9% 72.6%
3778293 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.62 57.0 3.96e-01 100.0% 72.5%
3935978 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.61 51.0 4.96e-01 90.1% 90.6%
5025402 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.61 52.0 4.33e-01 90.1% 83.4%
3581716 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.60 51.0 5.26e-01 90.8% 100.0%
3978228 603.1.1.122 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › IgaA 0.60 54.0 5.37e-01 100.0% 94.0%
3612403 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.60 52.0 5.20e-01 95.7% 91.7%
4586428 5059.1.1.2 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Multi_Drug_Res 0.60 43.0 4.74e-01 85.8% 95.5%
3764108 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.59 54.0 3.78e-01 99.3% 71.1%
3968183 3758.2.1.1 alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB 0.58 42.0 4.10e-01 75.9% 89.2%
3163928 1075.5.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt 0.58 42.0 3.78e-01 81.6% 54.4%
4369161 3615.1.1.0 alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain 0.58 51.0 5.21e-01 98.6% 98.6%
3944727 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.58 51.0 3.67e-01 100.0% 99.3%
4944333 633.10.1.0 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.57 46.0 4.88e-01 85.1% 96.0%
4337202 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.57 51.0 3.63e-01 97.2% 54.7%
3787888 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.57 50.0 3.46e-01 96.5% 96.9%
3311689 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.57 47.0 4.81e-01 90.8% 94.3%
3693645 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.57 47.0 4.66e-01 89.4% 85.3%
5051930 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.57 46.0 4.02e-01 85.1% 93.8%
4033205 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.56 43.0 3.94e-01 80.9% 86.8%
3714759 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.56 41.0 3.85e-01 75.9% 89.1%
4995444 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.56 46.0 4.14e-01 87.2% 94.9%
3592140 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.56 46.0 4.77e-01 87.9% 93.3%
4420971 109.25.1.1 alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A › GAIN 0.56 42.0 4.49e-01 81.6% 88.8%
3701816 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.56 42.0 4.57e-01 78.7% 95.0%
3655293 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.56 43.0 3.74e-01 84.4% 55.1%
3190870 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 44.0 3.48e-01 84.4% 65.1%
3715773 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.55 47.0 4.63e-01 90.8% 92.0%
3513983 109.25.1.1 alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A › GAIN 0.55 42.0 4.42e-01 83.7% 88.8%
3976441 633.10.1.0 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.55 44.0 4.66e-01 91.5% 97.6%
3232264 109.25.1.1 alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A › GAIN 0.55 41.0 4.38e-01 81.6% 88.8%
3576991 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.55 44.0 4.26e-01 98.6% 75.2%
3622326 109.25.1.1 alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A › GAIN 0.55 41.0 4.27e-01 83.0% 83.0%
4161991 604.12.1.4 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › ATG1-like_MIT1 0.54 42.0 4.06e-01 78.7% 81.3%
3523264 633.23.1.22 alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.54 43.0 4.47e-01 85.8% 100.0%
3864123 633.21.1.10 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › MARVEL 0.54 43.0 4.44e-01 85.8% 100.0%
3949246 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.53 36.0 3.47e-01 71.6% 58.8%
3880919 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.53 45.0 4.45e-01 90.1% 89.2%
2060764 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.53 44.0 4.61e-01 100.0% 98.4%
3224283 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.53 43.0 3.98e-01 90.1% 87.9%
3773479 633.21.1.23 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 0.52 43.0 4.53e-01 90.1% 95.4%
3879044 174.1.1.43 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 0.52 42.0 4.41e-01 83.0% 95.2%
4943557 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.52 43.0 4.51e-01 100.0% 100.0%
3901124 174.1.1.12 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › BCLP 0.52 42.0 4.21e-01 89.4% 94.7%
3742628 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.51 39.0 3.83e-01 80.1% 82.5%
4407105 1075.5.1.2 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ 0.50 39.0 3.23e-01 82.3% 73.8%