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CAKLQF020000009.1__CAH1083374.1__SAMEA5780031_01962__00057

Bact-Vir

CAKLQF020000009.1__CAH1083374.1__SAMEA5780031_01962__00057

Identity

Kingdom:
phage

Quality

94.1 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 36-157
PDB
Domain cluster: representative
CATH (63)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2o36A01 1.20.1050.40 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Endopeptidase. Chain P; domain 1 0.88 80.0 7.90e-01 95.9% 95.3%
4ka7A01 1.10.1370.40 Mainly Alpha › Orthogonal Bundle › Neurolysin; domain 3 › 0.86 78.0 5.21e-01 95.9% 28.8%
3kkbA00 1.20.120.880 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase (KinB), sensor domain 0.74 48.0 4.83e-01 79.5% 64.3%
3ay5A01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.72 52.0 5.07e-01 78.7% 68.4%
2m6bA00 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.70 49.0 4.62e-01 78.7% 58.7%
2c5iT00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 52.0 5.72e-01 79.5% 100.0%
1uurA01 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.70 53.0 5.51e-01 79.5% 98.2%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 53.0 5.39e-01 81.1% 95.8%
3vkgB03 1.20.58.1120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dynein motor heavy chain, linker domain, subdomain 4 0.69 50.0 4.58e-01 77.0% 58.3%
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.68 53.0 5.15e-01 82.8% 82.2%
1o5hA00 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.68 52.0 4.40e-01 82.0% 49.0%
4aifA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.67 45.0 4.22e-01 100.0% 57.6%
2o8pA00 1.20.190.20 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain 0.66 53.0 4.41e-01 86.9% 54.3%
3axjB01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.66 53.0 4.90e-01 96.7% 67.7%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.66 46.0 4.73e-01 78.7% 75.2%
3dyjA02 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.66 47.0 4.43e-01 79.5% 60.3%
1hs7A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 48.0 5.29e-01 81.1% 96.9%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 46.0 5.13e-01 73.0% 98.9%
6xxvC00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.65 49.0 5.13e-01 79.5% 100.0%
3tp3A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.65 55.0 5.20e-01 91.8% 96.6%
2pybA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.65 45.0 4.22e-01 72.1% 90.7%
2zcxA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.64 53.0 4.46e-01 89.3% 77.1%
2fonA04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.63 38.0 3.82e-01 74.6% 56.6%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.63 41.0 4.64e-01 86.1% 87.1%
3rx6A00 1.20.58.1090 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phage polarity suppression protein monomer 0.63 46.0 4.04e-01 77.0% 88.8%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.62 45.0 4.40e-01 77.9% 69.2%
3behB01 1.20.120.540 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels 0.62 43.0 4.41e-01 96.7% 74.4%
5zw7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.61 43.0 3.97e-01 74.6% 57.2%
3hiuD00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.61 48.0 4.46e-01 82.8% 94.1%
5c4yA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.61 51.0 4.91e-01 89.3% 99.3%
3ajmB02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.61 43.0 4.18e-01 77.0% 66.2%
3lsjA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.61 52.0 4.84e-01 92.6% 94.8%
3q5dA02 1.20.58.420 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP 0.61 43.0 4.69e-01 76.2% 90.7%
1gqiA03 3.90.1330.10 Alpha Beta › Alpha-Beta Complex › Alpha-d-glucuronidase, C-terminal Domain › Alpha-glucuronidase, C-terminal domain 0.61 54.0 4.39e-01 100.0% 86.1%
3fhnA04 1.20.58.670 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D 0.60 49.0 4.80e-01 93.4% 81.7%
3dyjA01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.60 49.0 4.45e-01 94.3% 64.5%
5iduC03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.60 42.0 3.83e-01 75.4% 54.7%
1st6A01 1.20.120.810 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle 0.59 43.0 3.39e-01 75.4% 38.4%
1sj7C00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.58 47.0 4.32e-01 94.3% 65.1%
4mo7A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 48.0 4.56e-01 89.3% 95.8%
5h5mA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.57 41.0 4.08e-01 78.7% 70.0%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.57 46.0 4.60e-01 94.3% 83.6%
7wujE01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.57 44.0 3.45e-01 82.0% 68.3%
2ycdA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.57 41.0 4.25e-01 77.0% 80.3%
4cqiA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 46.0 4.93e-01 91.8% 100.0%
4hyjA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.56 48.0 3.87e-01 98.4% 48.3%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.56 46.0 4.54e-01 97.5% 82.1%
6dewA01 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.56 44.0 3.88e-01 86.9% 82.1%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.55 39.0 3.99e-01 97.5% 74.6%
7q37A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.55 45.0 3.75e-01 100.0% 50.5%
3fseB02 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.54 44.0 4.21e-01 88.5% 97.9%
3c07B00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 46.0 3.91e-01 96.7% 88.3%
2lqgA00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.53 42.0 4.09e-01 84.4% 79.7%
4etrB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.53 45.0 4.56e-01 91.8% 97.5%
2l81A00 1.20.120.830 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain 0.53 47.0 4.17e-01 98.4% 75.6%
2np9A01 1.20.58.1300 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 43.0 4.22e-01 93.4% 80.6%
2wbiB03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.53 38.0 3.56e-01 77.0% 58.9%
2xgjA03 1.10.3380.30 Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › 0.53 38.0 3.15e-01 74.6% 74.9%
3rm5B02 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.52 43.0 3.57e-01 91.0% 71.9%
7akwA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.51 46.0 3.78e-01 98.4% 76.1%
4mudC00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.51 43.0 3.60e-01 92.6% 91.4%
4uiqB00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.50 35.0 3.32e-01 73.0% 87.6%
1dowA00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.50 41.0 3.54e-01 98.4% 54.1%
ECOD (71)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3270147 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.90 86.0 5.19e-01 100.0% 20.4%
3720939 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.90 85.0 5.12e-01 100.0% 17.7%
3740339 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.89 85.0 5.06e-01 100.0% 17.6%
5048086 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.89 84.0 5.14e-01 100.0% 20.0%
3848694 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.89 84.0 5.09e-01 100.0% 19.4%
3253011 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.89 84.0 5.06e-01 100.0% 19.0%
3493166 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.88 84.0 5.09e-01 100.0% 18.4%
3427723 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.88 84.0 5.04e-01 100.0% 19.0%
3963564 2498.1.1.8 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3,TOP_N 0.88 83.0 5.02e-01 100.0% 18.5%
3174734 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.88 83.0 5.02e-01 100.0% 18.7%
3290903 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.87 83.0 5.06e-01 100.0% 19.2%
4447987 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.87 82.0 4.90e-01 100.0% 18.1%
4030659 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.87 82.0 4.95e-01 100.0% 17.6%
4159906 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.87 82.0 4.93e-01 100.0% 17.6%
1101920 2498.1.1.8 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3,TOP_N 0.87 82.0 4.94e-01 100.0% 18.0%
3561231 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.86 82.0 4.94e-01 100.0% 19.3%
4366840 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.86 81.0 4.83e-01 100.0% 18.2%
3471599 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.84 80.0 4.80e-01 100.0% 18.6%
3234435 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.84 80.0 4.88e-01 100.0% 18.8%
3424566 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.73 50.0 5.81e-01 98.4% 100.0%
3197870 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.71 55.0 5.30e-01 80.3% 84.4%
3577937 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.71 54.0 5.52e-01 79.5% 87.0%
3696908 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.70 63.0 4.66e-01 100.0% 78.7%
3254975 603.2.1.2 alpha bundles › STAT-like › STAT › STAT › Dict-STAT-coil 0.69 53.0 5.50e-01 81.1% 88.7%
3516162 603.1.1.23 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Sec20 0.69 59.0 5.28e-01 93.4% 78.2%
3616967 603.1.1.97 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE 0.68 60.0 4.74e-01 96.7% 74.5%
3902495 603.1.1.23 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Sec20 0.68 59.0 4.89e-01 95.9% 70.9%
3971025 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.68 50.0 4.99e-01 78.7% 75.2%
3936807 603.1.1.1 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin 0.67 60.0 5.14e-01 96.7% 96.3%
3725031 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.67 59.0 5.42e-01 96.7% 75.6%
3892002 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.67 58.0 5.41e-01 95.9% 98.1%
3809724 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.66 50.0 4.85e-01 80.3% 77.1%
3870615 633.23.1.34 alpha bundles › Bromodomain-like › Claudin › Claudin › CD20 0.66 46.0 4.64e-01 93.4% 71.2%
3237761 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.64 48.0 5.17e-01 78.7% 97.0%
1447953 109.4.1.149 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › COG5_N,COG5_C 0.64 57.0 4.37e-01 99.2% 52.3%
3795 603.2.1.2 alpha bundles › STAT-like › STAT › STAT › Dict-STAT-coil 0.64 56.0 5.67e-01 95.1% 98.3%
3584034 3911.1.1.0 extended segments › Exosome complex protein LRP1 › Exosome complex protein LRP1 › Exosome complex protein LRP1 0.64 38.0 3.80e-01 76.2% 56.8%
3690563 150.1.1.81 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › SOG2 0.63 44.0 4.29e-01 72.1% 74.1%
3179258 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 56.0 4.58e-01 100.0% 83.9%
3668980 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.62 43.0 4.17e-01 70.5% 68.1%
3269429 603.2.1.2 alpha bundles › STAT-like › STAT › STAT › Dict-STAT-coil 0.62 53.0 5.47e-01 95.1% 98.3%
4372621 191.1.1.50 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › SlmA-like_C 0.62 53.0 4.97e-01 92.6% 96.0%
3980115 5069.1.1.15 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_C_asm 0.62 46.0 4.38e-01 77.9% 70.6%
3887645 633.21.1.10 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › MARVEL 0.61 43.0 4.25e-01 72.1% 67.7%
3758651 633.23.1.34 alpha bundles › Bromodomain-like › Claudin › Claudin › CD20 0.61 47.0 4.06e-01 80.3% 76.3%
4618995 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.61 46.0 4.97e-01 79.5% 98.0%
3907407 109.4.1.20 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RYDR_ITPR 0.61 53.0 3.20e-01 95.9% 87.5%
3342169 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 54.0 4.33e-01 98.4% 54.6%
3828 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.60 46.0 4.76e-01 99.2% 87.5%
4947205 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 53.0 4.56e-01 100.0% 99.5%
5005724 3755.3.1.637 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 0.60 41.0 3.36e-01 71.3% 38.3%
3416752 3890.1.1.0 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins 0.59 43.0 3.52e-01 80.3% 40.4%
3797265 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.59 43.0 4.27e-01 75.4% 73.6%
5077923 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.59 53.0 4.66e-01 100.0% 88.6%
3172094 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.59 50.0 4.70e-01 93.4% 87.3%
3206884 109.10.1.1 alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.58 52.0 4.24e-01 100.0% 74.5%
4019691 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.58 44.0 4.28e-01 81.1% 70.7%
4998508 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 53.0 4.58e-01 100.0% 66.3%
3253936 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.58 46.0 4.47e-01 98.4% 77.0%
3655748 601.1.2.118 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › CASP_dom 0.57 43.0 4.07e-01 78.7% 66.2%
3967098 191.1.1.0 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.57 48.0 4.41e-01 91.0% 91.6%
4651060 633.22.1.0 alpha bundles › Bromodomain-like › Vitamin K epoxide reductase (VKOR) › Vitamin K epoxide reductase (VKOR) 0.57 49.0 4.39e-01 92.6% 78.2%
3688917 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.56 43.0 4.28e-01 82.8% 80.0%
3243897 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.55 47.0 4.56e-01 97.5% 82.1%
5014336 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.55 48.0 4.54e-01 98.4% 80.7%
4310587 109.4.1.317 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Med5 0.55 44.0 3.95e-01 93.4% 60.6%
3259417 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.54 48.0 4.12e-01 100.0% 77.5%
3235200 5001.1.1.31 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › GPR180-TMEM145_TM 0.52 46.0 3.65e-01 97.5% 47.1%
4186985 605.1.1.191 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › NtrY_N 0.51 44.0 4.41e-01 94.3% 92.8%
3272618 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.50 43.0 4.00e-01 96.7% 74.2%
3873670 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.50 37.0 3.34e-01 82.0% 55.3%
D2 high residues 358-525_638-648
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01432.27 best Peptidase_M3 136.2 3.00e-39 89.4% 35.9%
CATH (16)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1i1iP02 3.40.390.10 Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › Collagenase (Catalytic Domain) 0.97 76.0 8.28e-01 78.8% 100.0%
4ka7A01 1.10.1370.40 Mainly Alpha › Orthogonal Bundle › Neurolysin; domain 3 › 0.94 91.0 6.62e-01 100.0% 59.1%
1y79101 1.10.1370.40 Mainly Alpha › Orthogonal Bundle › Neurolysin; domain 3 › 0.93 91.0 6.65e-01 100.0% 57.6%
2hc5A01 3.30.160.170 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › FlaG-like 0.67 28.0 3.73e-01 80.4% 69.4%
4akrA02 3.90.1150.210 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › F-actin capping protein, beta subunit 0.55 40.0 4.32e-01 95.5% 89.8%
2l8oA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.55 39.0 4.32e-01 93.9% 90.3%
1z94B00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.54 39.0 4.27e-01 91.1% 92.3%
4hrvA00 3.40.50.10610 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ABC-type transport auxiliary lipoprotein component 0.53 34.0 3.75e-01 93.3% 79.9%
1vw4502 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.53 28.0 3.80e-01 84.9% 100.0%
3ly7A01 3.40.50.11830 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.52 38.0 4.01e-01 89.4% 82.6%
2n3gA00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.52 23.0 3.42e-01 75.4% 100.0%
3tfzB00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.51 41.0 4.29e-01 92.2% 92.7%
1fwxA01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.51 40.0 3.01e-01 82.7% 58.2%
2ymsC00 2.40.10.480 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.51 22.0 3.24e-01 70.9% 93.3%
1oi0A00 3.40.140.10 Alpha Beta › 3-Layer(aba) Sandwich › Cytidine Deaminase; domain 2 › Cytidine Deaminase, domain 2 0.50 29.0 3.59e-01 81.0% 92.6%
1ilyA00 3.30.420.100 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.50 23.0 3.07e-01 77.7% 81.1%
ECOD (53)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3270147 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.96 94.0 6.02e-01 100.0% 45.8%
3720939 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.95 93.0 5.91e-01 100.0% 49.2%
3848694 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.95 93.0 5.95e-01 100.0% 44.3%
3591993 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.95 92.0 5.90e-01 100.0% 45.4%
3174734 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.94 92.0 5.90e-01 100.0% 45.9%
3471599 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.94 92.0 5.82e-01 100.0% 46.1%
3427723 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.94 92.0 5.89e-01 100.0% 44.1%
5048086 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.94 92.0 5.96e-01 100.0% 46.5%
3383377 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.94 92.0 5.88e-01 100.0% 44.6%
3561231 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.94 92.0 5.89e-01 100.0% 45.1%
3740339 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.94 91.0 5.79e-01 100.0% 45.3%
3597577 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.94 91.0 5.87e-01 100.0% 45.2%
3665695 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.94 91.0 6.42e-01 100.0% 68.4%
3253011 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.93 91.0 5.82e-01 100.0% 48.9%
3290903 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.93 91.0 5.93e-01 100.0% 45.0%
3282736 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.93 91.0 5.84e-01 100.0% 44.9%
3202957 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.93 91.0 5.70e-01 100.0% 44.9%
157490 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.93 91.0 5.82e-01 100.0% 44.6%
4447987 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.93 90.0 5.72e-01 100.0% 46.7%
3234435 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.93 91.0 5.86e-01 100.0% 47.6%
3493166 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.93 91.0 5.83e-01 100.0% 48.1%
4366840 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.93 90.0 5.65e-01 100.0% 43.2%
3963564 2498.1.1.8 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3,TOP_N 0.93 90.0 5.81e-01 100.0% 44.7%
4159906 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.93 90.0 5.72e-01 100.0% 45.0%
4584629 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.93 90.0 5.74e-01 100.0% 44.6%
3713254 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.92 90.0 5.86e-01 100.0% 55.4%
3592559 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.92 90.0 5.85e-01 100.0% 55.0%
4104252 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.92 89.0 5.63e-01 100.0% 45.8%
3403594 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.92 89.0 5.76e-01 100.0% 45.1%
3924357 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.92 89.0 5.85e-01 100.0% 50.2%
4260116 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.92 89.0 5.60e-01 100.0% 44.4%
4030659 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.90 88.0 5.62e-01 100.0% 45.2%
3519013 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.90 87.0 5.76e-01 100.0% 48.9%
3243200 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.89 86.0 5.54e-01 100.0% 43.8%
3490984 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.82 78.0 5.03e-01 100.0% 46.9%
4030348 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.78 75.0 4.93e-01 100.0% 49.8%
3995928 2498.1.1.6 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 0.74 70.0 4.64e-01 100.0% 44.0%
3970048 4292.2.1.0 a+b two layers › FlaG-like › MAGUK binding stalk (MBS) domain › MAGUK binding stalk (MBS) domain 0.65 28.0 4.17e-01 92.2% 92.3%
3396124 708.1.2.0 beta complex topology › ETN0001 domain-like › ETN0001 domain-like › Mss4-like 0.63 24.0 3.25e-01 92.7% 64.2%
4936581 331.10.2.0 a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › Bacterial S-adenosylmethionine decarboxylase 0.60 29.0 3.98e-01 78.8% 94.1%
3910034 708.1.2.9 beta complex topology › ETN0001 domain-like › ETN0001 domain-like › Mss4-like › YPEH2ZP 0.58 27.0 3.27e-01 92.2% 63.3%
3592743 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.58 28.0 3.94e-01 90.5% 100.0%
4057405 7503.1.1.3 a/b three-layered sandwiches › TolB, N-terminal domain › TolB, N-terminal domain › TolB, N-terminal domain › TolB_N 0.56 35.0 3.91e-01 93.9% 80.7%
3544618 4292.2.1.0 a+b two layers › FlaG-like › MAGUK binding stalk (MBS) domain › MAGUK binding stalk (MBS) domain 0.55 27.0 3.74e-01 93.9% 96.5%
4965137 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.54 40.0 4.50e-01 90.5% 100.0%
3743072 3435.1.1.2 a+b two layers › Recombination-associated protein rdgC › Recombination-associated protein rdgC › Recombination-associated protein rdgC › CENP-N 0.53 31.0 3.42e-01 92.2% 69.0%
4266613 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.53 26.0 3.62e-01 99.4% 97.6%
4623130 7503.1.1.18 a/b three-layered sandwiches › TolB, N-terminal domain › TolB, N-terminal domain › TolB, N-terminal domain › PF30449 0.53 34.0 3.84e-01 79.3% 85.2%
4970159 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.53 25.0 3.32e-01 77.1% 83.2%
4078209 7503.1.1.3 a/b three-layered sandwiches › TolB, N-terminal domain › TolB, N-terminal domain › TolB, N-terminal domain › TolB_N 0.52 33.0 3.64e-01 74.9% 77.9%
4401641 7503.1.1.3 a/b three-layered sandwiches › TolB, N-terminal domain › TolB, N-terminal domain › TolB, N-terminal domain › TolB_N 0.51 25.0 3.13e-01 79.9% 76.2%
3288021 2008.6.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Acetyl-CoA carboxylase AC4 and AC5 domains › Acetyl-CoA carboxylase AC4 and AC5 domains 0.51 40.0 4.03e-01 82.7% 95.0%
4113597 7503.1.1.3 a/b three-layered sandwiches › TolB, N-terminal domain › TolB, N-terminal domain › TolB, N-terminal domain › TolB_N 0.50 25.0 3.22e-01 79.3% 84.2%