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CAKLQF020000010.1__CAH1085037.1__SAMEA5780031_02141__00086
Bact-VirCAKLQF020000010.1__CAH1085037.1__SAMEA5780031_02141__00086
Identity
- Kingdom:
- phage
Quality
92.4
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 74-213
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02447.23 best | GntP_permease | 27.1 | 2.50e-06 | 97.1% | 26.6% |
CATH (18)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3h20A04 | 1.10.1240.50 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › | 0.72 | 45.0 | 5.50e-01 | 73.6% | 98.9% |
| 3zibC00 | 1.20.120.1620 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.63 | 43.0 | 5.00e-01 | 87.1% | 100.0% |
| 3ok8A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.59 | 42.0 | 3.64e-01 | 73.6% | 84.5% |
| 2z1qB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.57 | 34.0 | 3.45e-01 | 75.0% | 59.6% |
| 3nf2A00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.55 | 47.0 | 3.62e-01 | 95.0% | 51.5% |
| 6cxtB01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.55 | 40.0 | 4.40e-01 | 86.4% | 96.4% |
| 3shgA00 | 1.10.3290.10 | Mainly Alpha › Orthogonal Bundle › Fic-like fold › Fido-like domain | 0.53 | 42.0 | 3.78e-01 | 100.0% | 61.1% |
| 1nlxA00 | 1.20.120.320 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Group V grass pollen allergen | 0.52 | 35.0 | 3.94e-01 | 76.4% | 91.3% |
| 3juiA00 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.52 | 36.0 | 3.38e-01 | 100.0% | 57.5% |
| 1rx0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.52 | 34.0 | 3.30e-01 | 81.4% | 58.7% |
| 2bl2A00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.52 | 41.0 | 3.95e-01 | 82.1% | 87.8% |
| 2fulB00 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.51 | 40.0 | 3.85e-01 | 85.0% | 71.7% |
| 1io1A01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.51 | 41.0 | 3.85e-01 | 82.9% | 82.8% |
| 1r3dA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.51 | 43.0 | 3.56e-01 | 91.4% | 100.0% |
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.51 | 42.0 | 3.80e-01 | 87.1% | 86.7% |
| 7dl9B02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.51 | 41.0 | 3.63e-01 | 86.4% | 75.9% |
| 1xvpB00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.51 | 43.0 | 3.63e-01 | 93.6% | 87.4% |
| 1grlB01 | 1.10.560.10 | Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain | 0.50 | 39.0 | 3.25e-01 | 81.4% | 53.7% |
ECOD (24)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3163671 | 3355.1.1.11 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › GntP_permease | 0.88 | 79.0 | 5.47e-01 | 100.0% | 31.8% |
| 3839299 | 3355.1.1.8 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_H_antiporter | 0.84 | 73.0 | 5.05e-01 | 91.4% | 31.4% |
| 3971875 | 3355.1.1.0 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter | 0.84 | 73.0 | 4.98e-01 | 91.4% | 30.2% |
| 5074711 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.80 | 73.0 | 5.08e-01 | 99.3% | 32.6% |
| 3164464 | 3355.1.1.8 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_H_antiporter | 0.79 | 71.0 | 4.86e-01 | 99.3% | 29.6% |
| 4965432 | 3355.1.1.5 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › SCFA_trans | 0.79 | 71.0 | 4.78e-01 | 95.0% | 28.7% |
| 3591004 | 3355.1.1.8 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_H_antiporter | 0.79 | 69.0 | 4.75e-01 | 98.6% | 29.1% |
| 5064843 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.78 | 73.0 | 5.10e-01 | 100.0% | 82.4% |
| 3529438 | 3355.1.1.21 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_sulph_symp, CitMHS | 0.78 | 72.0 | 4.87e-01 | 100.0% | 29.2% |
| 4996200 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.78 | 72.0 | 4.96e-01 | 100.0% | 75.2% |
| 5009976 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.78 | 72.0 | 5.14e-01 | 100.0% | 35.9% |
| 3278891 | 3355.1.1.5 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › SCFA_trans | 0.76 | 71.0 | 4.84e-01 | 100.0% | 32.7% |
| 5029408 | 7064.1.1.1 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 | 0.62 | 44.0 | 4.35e-01 | 72.9% | 76.0% |
| 3994018 | 3286.1.1.1 ↗ | alpha complex topology › Glypican insertion domain › Glypican insertion domain › Glypican insertion domain › Glypican | 0.61 | 50.0 | 4.27e-01 | 87.1% | 73.8% |
| 3789188 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.60 | 44.0 | 3.56e-01 | 74.3% | 69.0% |
| 3875955 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.60 | 40.0 | 3.62e-01 | 70.7% | 49.7% |
| 3924369 | 5001.1.1.27 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Sre | 0.59 | 47.0 | 3.71e-01 | 84.3% | 85.3% |
| 3712041 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 46.0 | 3.57e-01 | 87.1% | 58.4% |
| 3959788 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.54 | 37.0 | 3.82e-01 | 84.3% | 73.3% |
| 3497215 | 109.26.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains | 0.53 | 41.0 | 3.52e-01 | 84.3% | 75.7% |
| 3451749 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.52 | 37.0 | 3.39e-01 | 73.6% | 82.0% |
| 3686419 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.52 | 40.0 | 3.91e-01 | 80.0% | 89.3% |
| 3739447 | 109.46.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Helical domain in TOPLESS related protein 2 (TPR2) › Helical domain in TOPLESS related protein 2 (TPR2) › CTLH | 0.51 | 39.0 | 3.96e-01 | 82.1% | 94.3% |
| 3502614 | 3881.1.1.1 ↗ | alpha bundles › CNOT9 binding domain CN9BD (DUF3819) › CNOT9 binding domain CN9BD (DUF3819) › CNOT9 binding domain CN9BD (DUF3819) › DUF3819 | 0.51 | 43.0 | 3.57e-01 | 90.7% | 76.2% |
D2
medium
residues 1-61
Domain cluster:
representative
CATH (22)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6m36O01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.69 | 50.0 | 4.38e-01 | 78.7% | 74.0% |
| 2iw3A02 | 1.20.1390.20 | Mainly Alpha › Up-down Bundle › PWI domain › | 0.67 | 52.0 | 4.57e-01 | 91.8% | 56.7% |
| 1l0oA00 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.67 | 49.0 | 3.83e-01 | 80.3% | 74.5% |
| 4dhiB02 | 1.20.1300.20 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Peptidase C65 Otubain, subdomain 2 | 0.67 | 49.0 | 3.72e-01 | 78.7% | 43.4% |
| 3ci0K02 | 1.10.40.60 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › EpsJ-like | 0.66 | 50.0 | 4.10e-01 | 86.9% | 44.2% |
| 3ibyD02 | 1.10.287.1770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.65 | 49.0 | 4.39e-01 | 80.3% | 89.3% |
| 2l35A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.64 | 43.0 | 4.31e-01 | 70.5% | 71.4% |
| 1a52A00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.64 | 55.0 | 3.73e-01 | 100.0% | 86.6% |
| 3triA02 | 1.10.3730.10 | Mainly Alpha › Orthogonal Bundle › ProC C-terminal domain-like fold › ProC C-terminal domain-like | 0.63 | 50.0 | 4.22e-01 | 98.4% | 51.5% |
| 2ddmB00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.62 | 51.0 | 3.38e-01 | 95.1% | 90.8% |
| 6cnzF00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.60 | 44.0 | 3.34e-01 | 80.3% | 80.4% |
| 4s1hA00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.60 | 52.0 | 3.36e-01 | 100.0% | 83.6% |
| 5ts9B00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.59 | 43.0 | 3.25e-01 | 80.3% | 79.5% |
| 1ij5A01 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 40.0 | 3.72e-01 | 70.5% | 75.0% |
| 2c4eA00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.58 | 43.0 | 2.75e-01 | 78.7% | 95.0% |
| 2abqA00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.57 | 47.0 | 3.05e-01 | 96.7% | 70.5% |
| 1xdxA01 | 3.30.1140.40 | Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › Tctex-1 | 0.56 | 47.0 | 4.05e-01 | 96.7% | 65.0% |
| 4rocA01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.55 | 43.0 | 3.78e-01 | 93.4% | 56.3% |
| 5k29A00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.53 | 44.0 | 3.88e-01 | 98.4% | 73.2% |
| 5vc2A02 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.52 | 41.0 | 3.29e-01 | 93.4% | 81.6% |
| 1dcnA03 | 1.10.40.30 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) | 0.52 | 38.0 | 3.69e-01 | 95.1% | 70.8% |
| 1l5jA03 | 3.40.1060.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aconitase; Domain 2 › Aconitase, Domain 2 | 0.50 | 39.0 | 2.89e-01 | 86.9% | 45.1% |
ECOD (5)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4519766 | 633.6.1.2 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX | 0.72 | 49.0 | 3.32e-01 | 70.5% | 20.5% |
| 4223484 | 225.1.1.6 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_2 | 0.71 | 52.0 | 3.92e-01 | 78.7% | 71.3% |
| 4351255 | 191.1.1.91 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › PF29842 | 0.68 | 51.0 | 4.50e-01 | 80.3% | 84.4% |
| 4145393 | 3579.1.1.6 ↗ | extended segments › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › MbhD+MbhE | 0.53 | 46.0 | 3.36e-01 | 100.0% | 90.0% |
| 4968943 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.53 | 42.0 | 3.95e-01 | 98.4% | 92.9% |
D3
medium
residues 235-334
Domain cluster:
representative
CATH (20)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4ysxC00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.62 | 45.0 | 3.93e-01 | 77.0% | 51.0% |
| 4mycA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.62 | 54.0 | 3.84e-01 | 100.0% | 50.3% |
| 16vpA00 | 1.10.1290.10 | Mainly Alpha › Orthogonal Bundle › Conserved core of transcriptional regulatory protein vp16 › Alpha trans-inducing (Alpha-TIF) | 0.58 | 47.0 | 3.33e-01 | 89.0% | 58.8% |
| 1yhlA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.57 | 49.0 | 3.45e-01 | 100.0% | 80.4% |
| 2i0mA02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.56 | 34.0 | 3.46e-01 | 77.0% | 60.4% |
| 3udcA01 | 1.10.287.1260 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.56 | 45.0 | 4.39e-01 | 90.0% | 77.4% |
| 2gtaA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.56 | 39.0 | 4.00e-01 | 91.0% | 75.3% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.56 | 40.0 | 3.84e-01 | 75.0% | 99.1% |
| 4nqiD00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.55 | 40.0 | 3.15e-01 | 77.0% | 55.6% |
| 1x04A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.55 | 40.0 | 3.26e-01 | 78.0% | 67.5% |
| 1jadA00 | 1.20.1230.10 | Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain | 0.54 | 47.0 | 3.59e-01 | 97.0% | 83.5% |
| 4an8A02 | 1.10.132.100 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.53 | 41.0 | 3.84e-01 | 92.0% | 66.4% |
| 3pwxA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.53 | 39.0 | 3.22e-01 | 78.0% | 79.9% |
| 1jwnA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.53 | 38.0 | 3.37e-01 | 75.0% | 52.4% |
| 4nswB01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.52 | 39.0 | 2.99e-01 | 82.0% | 64.8% |
| 2wyhB04 | 1.20.1270.50 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain | 0.51 | 34.0 | 3.43e-01 | 78.0% | 66.3% |
| 2jqqA00 | 1.20.58.1240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 37.0 | 3.23e-01 | 76.0% | 76.0% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.51 | 36.0 | 3.36e-01 | 75.0% | 78.6% |
| 4mh6A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.51 | 37.0 | 3.21e-01 | 77.0% | 47.8% |
| 2rdcA00 | 1.10.287.800 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 | 0.50 | 43.0 | 3.89e-01 | 93.0% | 78.2% |
ECOD (31)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4958930 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.67 | 49.0 | 4.48e-01 | 76.0% | 86.9% |
| 4664704 | 3755.3.1.299 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF445 | 0.65 | 48.0 | 3.72e-01 | 76.0% | 37.1% |
| 4508775 | 5063.1.1.0 ↗ | alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK | 0.65 | 48.0 | 4.90e-01 | 76.0% | 82.1% |
| 4989989 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.65 | 47.0 | 4.93e-01 | 90.0% | 84.4% |
| 4995732 | 604.32.1.0 ↗ | alpha bundles › Spectrin repeat-like › Recombination protein uvsY › Recombination protein uvsY | 0.61 | 43.0 | 3.83e-01 | 78.0% | 51.4% |
| 3713451 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.61 | 43.0 | 3.91e-01 | 71.0% | 54.6% |
| 3174080 | 6169.1.1.0 ↗ | extended segments › Transmembrane segment of lysosome-associated membrane glycoprotein 2 › Transmembrane segment of lysosome-associated membrane glycoprotein 2 › Transmembrane segment of lysosome-associated membrane glycoprotein 2 | 0.61 | 45.0 | 4.71e-01 | 77.0% | 86.7% |
| 5048512 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.60 | 44.0 | 4.54e-01 | 78.0% | 81.1% |
| 3955855 | 1079.1.1.0 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA | 0.60 | 44.0 | 3.39e-01 | 77.0% | 66.5% |
| 3528691 | 601.19.1.20 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Fy-3 | 0.60 | 41.0 | 3.89e-01 | 77.0% | 57.6% |
| 3957435 | 5058.1.1.2 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st | 0.59 | 49.0 | 4.69e-01 | 93.0% | 84.2% |
| 4938119 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.58 | 46.0 | 4.65e-01 | 94.0% | 88.0% |
| 3398929 | 5041.1.1.32 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › TMEM141 | 0.57 | 41.0 | 4.33e-01 | 77.0% | 84.4% |
| 3576249 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.55 | 42.0 | 3.97e-01 | 94.0% | 67.2% |
| 3600869 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.54 | 40.0 | 3.87e-01 | 78.0% | 68.7% |
| 3990182 | 3922.1.1.226 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Fy-3 | 0.54 | 40.0 | 3.84e-01 | 78.0% | 86.1% |
| 3785344 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.54 | 39.0 | 3.76e-01 | 78.0% | 66.7% |
| 3695212 | 601.19.1.18 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Mmc1_C | 0.53 | 47.0 | 3.37e-01 | 98.0% | 33.7% |
| 4972169 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.53 | 38.0 | 3.67e-01 | 77.0% | 95.0% |
| 4547657 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.53 | 43.0 | 3.31e-01 | 90.0% | 68.4% |
| 4880296 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.53 | 33.0 | 3.51e-01 | 76.0% | 71.3% |
| 3968997 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.52 | 37.0 | 3.40e-01 | 73.0% | 83.1% |
| 3967398 | 3755.1.1.1 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › YscO | 0.52 | 38.0 | 3.36e-01 | 77.0% | 51.3% |
| 3962942 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.52 | 35.0 | 3.13e-01 | 74.0% | 46.0% |
| 3521098 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.51 | 40.0 | 3.47e-01 | 84.0% | 99.4% |
| 3968781 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.51 | 37.0 | 3.36e-01 | 77.0% | 95.9% |
| 4956012 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.51 | 35.0 | 3.46e-01 | 74.0% | 66.7% |
| 3597345 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.51 | 37.0 | 3.57e-01 | 76.0% | 78.3% |
| 3815117 | 1065.1.1.0 ↗ | alpha bundles › SPX domain › SPX domain › SPX domain | 0.50 | 38.0 | 3.75e-01 | 81.0% | 85.5% |
| 3967393 | 601.4.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › 4HB_MCP_1 | 0.50 | 37.0 | 3.00e-01 | 78.0% | 93.5% |
| 5063047 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.50 | 36.0 | 3.65e-01 | 75.0% | 75.0% |
D4
medium
residues 335-473
Domain cluster:
representative
CATH (19)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2yx8A00 | 1.10.150.510 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Receptor activity modifying family | 0.70 | 29.0 | 3.83e-01 | 74.1% | 67.9% |
| 7cj3A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.61 | 48.0 | 3.93e-01 | 82.7% | 53.9% |
| 3c2bA01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.60 | 24.0 | 3.85e-01 | 71.2% | 100.0% |
| 2oi8A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 49.0 | 4.36e-01 | 95.0% | 87.2% |
| 1mqsA04 | 1.25.40.60 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.56 | 36.0 | 4.05e-01 | 76.3% | 86.4% |
| 2ibdA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 47.0 | 4.69e-01 | 95.7% | 93.2% |
| 4bejB02 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.54 | 41.0 | 3.56e-01 | 81.3% | 90.6% |
| 6gpxB00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.54 | 42.0 | 3.45e-01 | 83.5% | 82.9% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.53 | 42.0 | 4.32e-01 | 84.2% | 96.9% |
| 3dd7C00 | 1.20.120.1870 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Fic/DOC protein, Fido domain | 0.53 | 39.0 | 4.13e-01 | 98.6% | 86.9% |
| 7zcvA02 | 1.25.40.400 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.53 | 36.0 | 3.20e-01 | 95.0% | 45.2% |
| 2nq2A00 | 1.10.3470.10 | Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC | 0.52 | 41.0 | 3.23e-01 | 84.2% | 66.2% |
| 3mvuA00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.52 | 39.0 | 3.34e-01 | 77.7% | 86.6% |
| 2bl2A00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.52 | 39.0 | 3.79e-01 | 79.1% | 91.0% |
| 2fp1B00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.51 | 39.0 | 3.69e-01 | 79.9% | 95.7% |
| 1kplA00 | 1.10.3080.10 | Mainly Alpha › Orthogonal Bundle › Clc chloride channel › Clc chloride channel | 0.51 | 44.0 | 3.18e-01 | 96.4% | 87.7% |
| 3ckdA02 | 1.20.58.360 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Shigella T3SS effector IpaH defines | 0.51 | 34.0 | 3.55e-01 | 93.5% | 75.0% |
| 6gy8A01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.50 | 39.0 | 3.02e-01 | 82.7% | 79.8% |
| 3fmsA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.50 | 39.0 | 3.90e-01 | 80.6% | 93.6% |
ECOD (6)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3163671 | 3355.1.1.11 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › GntP_permease | 0.80 | 73.0 | 5.06e-01 | 96.4% | 32.3% |
| 5007958 | 3355.1.1.4 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › DctM | 0.72 | 66.0 | 4.53e-01 | 100.0% | 29.7% |
| 5074130 | 1075.1.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain | 0.59 | 54.0 | 4.42e-01 | 100.0% | 87.1% |
| 4430792 | 192.29.1.52 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Anthrone_oxy | 0.55 | 43.0 | 4.08e-01 | 82.7% | 100.0% |
| 3438493 | 632.15.1.5 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) › Rx_N | 0.53 | 37.0 | 3.66e-01 | 74.8% | 67.6% |
| 4028572 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.52 | 36.0 | 3.16e-01 | 70.5% | 69.5% |