←Back to structures
CAKLQF020000013.1__CAH1086929.1__SAMEA5780031_02540__00076
Bact-VirCAKLQF020000013.1__CAH1086929.1__SAMEA5780031_02540__00076
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 1-137_385-408
Domain cluster:
representative
CATH (45)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1a7eA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.78 | 49.0 | 5.68e-01 | 77.0% | 86.4% |
| 1cxzB00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.76 | 33.0 | 4.51e-01 | 84.5% | 77.9% |
| 4xpwA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.75 | 53.0 | 5.82e-01 | 79.5% | 87.8% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.75 | 53.0 | 5.79e-01 | 79.5% | 87.2% |
| 3na7A00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.73 | 34.0 | 2.96e-01 | 85.1% | 30.0% |
| 3cwzB01 | 1.20.58.900 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain | 0.73 | 47.0 | 4.92e-01 | 100.0% | 70.5% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.71 | 49.0 | 5.64e-01 | 82.0% | 100.0% |
| 3vkgA12 | 1.10.287.2610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.70 | 34.0 | 3.09e-01 | 85.1% | 34.9% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.69 | 44.0 | 4.77e-01 | 83.2% | 76.3% |
| 2l81A00 | 1.20.120.830 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain | 0.69 | 56.0 | 5.46e-01 | 85.1% | 96.6% |
| 3rfyA02 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.69 | 46.0 | 5.43e-01 | 77.6% | 100.0% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.69 | 54.0 | 5.82e-01 | 97.5% | 97.0% |
| 3iqcA00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.69 | 44.0 | 5.05e-01 | 79.5% | 87.4% |
| 1orjD00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.68 | 46.0 | 5.08e-01 | 82.6% | 87.2% |
| 2yfaB01 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.66 | 47.0 | 5.32e-01 | 78.9% | 97.5% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.66 | 31.0 | 4.09e-01 | 84.5% | 81.2% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.66 | 50.0 | 5.44e-01 | 83.2% | 96.9% |
| 7drjB01 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.65 | 54.0 | 5.23e-01 | 96.3% | 77.6% |
| 4g80T00 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.65 | 51.0 | 5.43e-01 | 95.7% | 95.0% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.64 | 50.0 | 5.52e-01 | 92.5% | 100.0% |
| 1z6oM00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.63 | 44.0 | 4.18e-01 | 71.4% | 90.1% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.63 | 48.0 | 5.23e-01 | 94.4% | 99.2% |
| 1xzpA02 | 1.20.120.430 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 | 0.61 | 51.0 | 5.07e-01 | 100.0% | 86.7% |
| 3pf0A00 | 1.20.1420.20 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › M75 peptidase, HXXE motif | 0.61 | 53.0 | 4.17e-01 | 91.9% | 97.5% |
| 1jogA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.61 | 46.0 | 4.99e-01 | 78.9% | 98.5% |
| 4hwdD00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.59 | 32.0 | 4.20e-01 | 72.7% | 95.6% |
| 4k1pE00 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.59 | 46.0 | 3.70e-01 | 83.2% | 83.1% |
| 3thxB03 | 1.10.1420.10 | Mainly Alpha › Orthogonal Bundle › MutS, DNA mismatch repair protein; Chain A, domain 3 › | 0.57 | 37.0 | 3.58e-01 | 87.6% | 56.5% |
| 4hwhE00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.56 | 31.0 | 3.99e-01 | 72.0% | 95.5% |
| 4nwpD00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.56 | 42.0 | 4.34e-01 | 94.4% | 83.2% |
| 1st6A01 | 1.20.120.810 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle | 0.55 | 50.0 | 4.29e-01 | 98.8% | 78.0% |
| 2yayA02 | 1.20.1670.10 | Mainly Alpha › Up-down Bundle › all-alpha NTP pyrophosphatase › Type II deoxyuridine triphosphatase | 0.54 | 39.0 | 4.22e-01 | 73.3% | 87.4% |
| 6o7uc01 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.54 | 41.0 | 3.95e-01 | 80.7% | 76.3% |
| 3ljbA00 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.53 | 48.0 | 4.30e-01 | 96.9% | 85.4% |
| 1nfvA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.53 | 44.0 | 4.35e-01 | 88.2% | 98.8% |
| 3cqcA00 | 1.20.190.50 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › | 0.53 | 39.0 | 3.35e-01 | 100.0% | 49.4% |
| 3syvA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.52 | 40.0 | 3.48e-01 | 80.1% | 86.5% |
| 4l8iB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.52 | 33.0 | 3.92e-01 | 91.3% | 92.0% |
| 4hkaA01 | 1.20.58.480 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 45.0 | 3.69e-01 | 93.8% | 81.3% |
| 6hwjA01 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.51 | 38.0 | 3.34e-01 | 77.0% | 80.8% |
| 3l39A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.51 | 43.0 | 4.10e-01 | 95.0% | 100.0% |
| 2wauA02 | 1.20.58.830 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 36.0 | 4.16e-01 | 73.3% | 99.2% |
| 2chnB03 | 1.20.58.460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like | 0.51 | 38.0 | 3.66e-01 | 85.1% | 68.9% |
| 4p3fA00 | 1.10.3450.40 | Mainly Alpha › Orthogonal Bundle › Hyaluronidase domain-like › Signal recognition particle, SRP68 subunit, RNA-binding domain | 0.51 | 37.0 | 3.55e-01 | 93.2% | 62.7% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.50 | 35.0 | 3.88e-01 | 89.4% | 87.2% |
ECOD (55)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3273217 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.79 | 33.0 | 4.28e-01 | 84.5% | 66.3% |
| 4618995 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.74 | 33.0 | 4.13e-01 | 85.1% | 67.0% |
| 5061118 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.73 | 55.0 | 6.14e-01 | 96.9% | 100.0% |
| 3572847 | 604.1.1.162 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › DUF4716 | 0.72 | 31.0 | 3.67e-01 | 85.1% | 56.5% |
| 3609189 | 192.29.1.19 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon | 0.68 | 52.0 | 4.95e-01 | 83.2% | 67.9% |
| 4561197 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.67 | 54.0 | 4.94e-01 | 83.2% | 89.3% |
| 5011760 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.67 | 50.0 | 5.55e-01 | 93.2% | 100.0% |
| 3356672 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.66 | 50.0 | 5.49e-01 | 83.2% | 100.0% |
| 3400725 | 192.29.1.19 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon | 0.65 | 51.0 | 5.44e-01 | 83.9% | 96.3% |
| 3175135 | 601.1.1.25 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › GIT1_C | 0.65 | 55.0 | 5.68e-01 | 97.5% | 92.9% |
| 3688451 | 192.29.1.19 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon | 0.65 | 49.0 | 5.29e-01 | 83.9% | 92.0% |
| 3740238 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.65 | 55.0 | 5.53e-01 | 98.8% | 89.9% |
| 3823532 | 192.29.1.19 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon | 0.65 | 49.0 | 5.12e-01 | 83.9% | 86.9% |
| 3217606 | 192.29.1.172 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF29678 | 0.65 | 50.0 | 4.87e-01 | 83.9% | 72.8% |
| 4441047 | 601.4.1.50 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › DUF6376 | 0.65 | 47.0 | 5.28e-01 | 82.6% | 96.8% |
| 4038749 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.64 | 45.0 | 5.14e-01 | 78.9% | 100.0% |
| 3267624 | 192.29.1.19 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon | 0.64 | 50.0 | 5.36e-01 | 81.4% | 97.8% |
| 4441744 | 601.4.1.78 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › DAHL | 0.64 | 49.0 | 5.39e-01 | 96.3% | 100.0% |
| 4030678 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.64 | 52.0 | 5.42e-01 | 96.9% | 95.2% |
| 3515340 | 601.3.1.16 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Cornichon | 0.63 | 49.0 | 5.11e-01 | 83.9% | 90.3% |
| 3739021 | 192.29.1.50 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PTPLA | 0.63 | 56.0 | 5.14e-01 | 94.4% | 95.1% |
| 3594098 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.62 | 56.0 | 5.03e-01 | 96.9% | 95.9% |
| 5082279 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.62 | 44.0 | 4.96e-01 | 97.5% | 98.3% |
| 3620358 | 192.29.1.50 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PTPLA | 0.61 | 55.0 | 4.94e-01 | 96.9% | 96.4% |
| 4565794 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.61 | 49.0 | 5.17e-01 | 84.5% | 100.0% |
| 3964598 | 192.29.1.104 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF4149 | 0.61 | 51.0 | 5.37e-01 | 98.8% | 100.0% |
| 4493088 | 601.1.2.75 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PTPLA | 0.61 | 54.0 | 4.88e-01 | 96.3% | 95.0% |
| 3926240 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.61 | 51.0 | 4.32e-01 | 90.7% | 89.6% |
| 3268551 | 5054.1.1.71 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › PTPLA | 0.61 | 53.0 | 4.82e-01 | 94.4% | 94.9% |
| 3587850 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.60 | 48.0 | 5.05e-01 | 83.9% | 99.3% |
| 5062318 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.60 | 50.0 | 4.89e-01 | 91.3% | 88.9% |
| 3236489 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.60 | 44.0 | 4.77e-01 | 98.1% | 91.9% |
| 3768341 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.59 | 47.0 | 4.31e-01 | 82.6% | 88.3% |
| 3340986 | 601.51.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-helical domain in phase 1 flagellin › alpha-helical domain in phase 1 flagellin | 0.58 | 45.0 | 4.27e-01 | 83.2% | 87.5% |
| 3474661 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.58 | 37.0 | 4.33e-01 | 70.2% | 89.6% |
| 3061928 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.57 | 50.0 | 4.80e-01 | 96.9% | 98.9% |
| 4526844 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.57 | 49.0 | 4.85e-01 | 95.0% | 94.3% |
| 3212811 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.56 | 44.0 | 4.80e-01 | 91.3% | 100.0% |
| 3943911 | 192.29.1.3 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › YliH | 0.56 | 40.0 | 4.55e-01 | 94.4% | 100.0% |
| 5009681 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.56 | 45.0 | 4.77e-01 | 92.5% | 98.6% |
| 3677692 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.55 | 46.0 | 4.78e-01 | 98.8% | 98.6% |
| 4534881 | 192.29.1.162 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DAHL | 0.55 | 48.0 | 4.56e-01 | 96.3% | 100.0% |
| 4958350 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.54 | 42.0 | 3.94e-01 | 84.5% | 64.2% |
| 3172105 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.54 | 35.0 | 4.18e-01 | 93.2% | 96.4% |
| 5020632 | 1075.5.1.8 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 | 0.54 | 41.0 | 3.75e-01 | 82.6% | 58.2% |
| 3485540 | 603.1.1.1 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin | 0.54 | 36.0 | 3.53e-01 | 91.3% | 61.7% |
| 3243709 | 603.1.1.97 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE | 0.54 | 50.0 | 4.44e-01 | 100.0% | 86.7% |
| 3908015 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.54 | 43.0 | 3.97e-01 | 98.8% | 65.6% |
| 4458494 | 3684.1.1.23 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › CA109-like | 0.52 | 45.0 | 4.40e-01 | 94.4% | 97.7% |
| 4465482 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.52 | 41.0 | 3.74e-01 | 83.9% | 65.6% |
| 4013887 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.51 | 40.0 | 4.24e-01 | 93.8% | 96.4% |
| 4022845 | 1065.1.1.1 ↗ | alpha bundles › SPX domain › SPX domain › SPX domain › SPX | 0.51 | 38.0 | 3.38e-01 | 76.4% | 62.7% |
| 4012358 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.51 | 39.0 | 4.09e-01 | 93.8% | 88.3% |
| 3699448 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.50 | 33.0 | 3.34e-01 | 84.5% | 65.5% |
| 3430175 | 601.4.1.68 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › Rx_N | 0.50 | 40.0 | 4.16e-01 | 91.9% | 95.8% |
D2
high
residues 146-263
Domain cluster:
representative
CATH (69)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1fioA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.77 | 70.0 | 5.91e-01 | 97.5% | 96.8% |
| 3ma5A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.76 | 46.0 | 5.23e-01 | 91.5% | 80.0% |
| 1zeeA01 | 1.20.58.600 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 64.0 | 6.41e-01 | 89.8% | 96.6% |
| 4wnfA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.76 | 60.0 | 4.63e-01 | 93.2% | 38.8% |
| 4yvoA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.74 | 50.0 | 5.02e-01 | 93.2% | 68.1% |
| 2v6yA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.74 | 46.0 | 5.69e-01 | 80.5% | 100.0% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 55.0 | 4.82e-01 | 80.5% | 74.6% |
| 2katA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.71 | 48.0 | 4.85e-01 | 92.4% | 70.4% |
| 2d2sA01 | 1.20.58.1210 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain | 0.70 | 49.0 | 4.98e-01 | 89.8% | 72.4% |
| 2qywA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.70 | 52.0 | 5.77e-01 | 79.7% | 97.9% |
| 3kezA01 | 1.25.40.390 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.69 | 62.0 | 4.89e-01 | 96.6% | 52.8% |
| 3vtxB00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.69 | 43.0 | 3.72e-01 | 89.0% | 39.9% |
| 7nmqA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.69 | 53.0 | 3.76e-01 | 80.5% | 74.3% |
| 1tqgA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.69 | 45.0 | 4.81e-01 | 72.9% | 75.2% |
| 1zu2A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.68 | 52.0 | 4.75e-01 | 98.3% | 60.1% |
| 2c41C01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.68 | 53.0 | 4.89e-01 | 81.4% | 97.3% |
| 2nrjA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.68 | 52.0 | 3.79e-01 | 81.4% | 64.5% |
| 7qihA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.68 | 41.0 | 4.35e-01 | 87.3% | 68.3% |
| 2p58C00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.68 | 38.0 | 3.92e-01 | 92.4% | 56.2% |
| 1tjoB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.68 | 52.0 | 4.58e-01 | 81.4% | 83.4% |
| 1u89A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.67 | 47.0 | 4.47e-01 | 75.4% | 61.2% |
| 3zgzA04 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.67 | 46.0 | 4.02e-01 | 84.7% | 46.9% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.67 | 42.0 | 4.55e-01 | 72.0% | 75.0% |
| 1jgcA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.66 | 50.0 | 4.50e-01 | 78.8% | 83.7% |
| 3hiuD00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.66 | 50.0 | 4.64e-01 | 80.5% | 90.1% |
| 3r2kA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.66 | 49.0 | 4.53e-01 | 78.8% | 87.0% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.65 | 47.0 | 4.75e-01 | 78.0% | 74.2% |
| 1e2aA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.65 | 49.0 | 5.17e-01 | 78.8% | 93.1% |
| 4gmnA00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.65 | 57.0 | 3.71e-01 | 98.3% | 37.6% |
| 3myvA01 | 1.25.40.390 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.65 | 55.0 | 4.43e-01 | 94.1% | 52.3% |
| 2fjcB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.65 | 50.0 | 4.60e-01 | 82.2% | 93.6% |
| 2chpA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.65 | 50.0 | 4.63e-01 | 81.4% | 98.0% |
| 1wpaA01 | 6.10.140.340 | Special › Helix non-globular › Helix Hairpins › | 0.64 | 50.0 | 5.44e-01 | 94.9% | 94.9% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.64 | 48.0 | 4.69e-01 | 79.7% | 91.7% |
| 2vxxA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.64 | 49.0 | 4.37e-01 | 81.4% | 85.5% |
| 2gd5A00 | 6.10.140.1230 | Special › Helix non-globular › Helix Hairpins › | 0.64 | 40.0 | 3.80e-01 | 83.1% | 51.4% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.64 | 44.0 | 4.27e-01 | 70.3% | 65.6% |
| 2yinA03 | 1.20.58.740 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DOCK DHR2 domain, lobe C | 0.64 | 56.0 | 5.50e-01 | 95.8% | 98.4% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 48.0 | 5.05e-01 | 79.7% | 100.0% |
| 7p3rA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.63 | 47.0 | 3.48e-01 | 79.7% | 80.6% |
| 2qqyA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.63 | 48.0 | 4.63e-01 | 82.2% | 98.6% |
| 1zs3A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.63 | 48.0 | 4.31e-01 | 82.2% | 88.9% |
| 3iq1B00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.62 | 48.0 | 4.35e-01 | 82.2% | 91.8% |
| 1nzeA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.61 | 41.0 | 4.22e-01 | 74.6% | 71.4% |
| 2jbwA01 | 1.20.1440.110 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase | 0.61 | 43.0 | 4.53e-01 | 82.2% | 82.5% |
| 1io1A01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.61 | 46.0 | 4.11e-01 | 79.7% | 64.5% |
| 4cmyA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.61 | 46.0 | 4.19e-01 | 80.5% | 83.4% |
| 1s3qG00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.61 | 46.0 | 4.19e-01 | 80.5% | 84.0% |
| 3fseB02 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.61 | 46.0 | 4.36e-01 | 80.5% | 96.5% |
| 3unoE00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.61 | 45.0 | 4.00e-01 | 77.1% | 80.2% |
| 2gs4A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.61 | 46.0 | 4.22e-01 | 80.5% | 94.9% |
| 4jhrB00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.61 | 54.0 | 4.00e-01 | 95.8% | 42.9% |
| 3ggyA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.61 | 44.0 | 3.81e-01 | 86.4% | 48.4% |
| 1l8nA03 | 3.90.1330.10 | Alpha Beta › Alpha-Beta Complex › Alpha-d-glucuronidase, C-terminal Domain › Alpha-glucuronidase, C-terminal domain | 0.60 | 49.0 | 4.11e-01 | 88.1% | 90.2% |
| 2a9uA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.60 | 42.0 | 4.18e-01 | 81.4% | 69.0% |
| 1nfvA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.59 | 46.0 | 4.09e-01 | 82.2% | 81.7% |
| 6w08A01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.59 | 45.0 | 3.23e-01 | 80.5% | 70.5% |
| 3ro3A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.57 | 51.0 | 4.58e-01 | 95.8% | 73.0% |
| 2hjmA01 | 1.20.120.460 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › protein pf1176 like | 0.57 | 36.0 | 4.08e-01 | 80.5% | 86.0% |
| 2wdqD00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.57 | 44.0 | 4.65e-01 | 81.4% | 93.3% |
| 3t9jA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.57 | 42.0 | 3.97e-01 | 78.0% | 97.9% |
| 3n71A03 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.57 | 50.0 | 4.17e-01 | 98.3% | 71.8% |
| 7zo9A01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.54 | 46.0 | 3.43e-01 | 93.2% | 93.6% |
| 3zsuA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.53 | 46.0 | 4.69e-01 | 95.8% | 97.5% |
| 1iqpA03 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.53 | 33.0 | 3.66e-01 | 86.4% | 78.7% |
| 2z1qB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.51 | 38.0 | 3.64e-01 | 77.1% | 69.9% |
| 4od4A01 | 1.10.357.140 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › UbiA prenyltransferase | 0.51 | 46.0 | 4.21e-01 | 97.5% | 80.8% |
| 1bgfA00 | 1.10.532.10 | Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain | 0.51 | 40.0 | 3.96e-01 | 87.3% | 77.4% |
| 2wb7A03 | 1.20.120.870 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain | 0.50 | 44.0 | 4.26e-01 | 96.6% | 86.8% |
ECOD (60)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4881789 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.86 | 61.0 | 7.05e-01 | 94.9% | 98.9% |
| 3176648 | 603.1.1.6 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin_2 | 0.81 | 71.0 | 5.84e-01 | 93.2% | 100.0% |
| 4873681 | 109.3.1.211 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › ANAPC5 | 0.79 | 57.0 | 5.36e-01 | 94.9% | 61.5% |
| 3917600 | 604.1.1.6 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_4 | 0.79 | 61.0 | 6.10e-01 | 80.5% | 83.3% |
| 1760269 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.77 | 59.0 | 5.98e-01 | 79.7% | 92.2% |
| 3389567 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.76 | 57.0 | 4.84e-01 | 78.8% | 74.7% |
| 3771613 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.75 | 58.0 | 4.97e-01 | 80.5% | 57.2% |
| 3552989 | 604.8.1.1 ↗ | alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo › Smac_DIABLO | 0.75 | 58.0 | 4.92e-01 | 80.5% | 71.2% |
| 4881792 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.75 | 64.0 | 5.95e-01 | 91.5% | 75.9% |
| 5073155 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.73 | 54.0 | 3.90e-01 | 88.1% | 28.1% |
| 3466941 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.73 | 56.0 | 4.57e-01 | 80.5% | 60.6% |
| 3975940 | 601.4.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TorS_sensor_domain | 0.73 | 49.0 | 4.52e-01 | 80.5% | 54.0% |
| 3442863 | 633.4.1.0 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor | 0.73 | 50.0 | 4.45e-01 | 80.5% | 49.4% |
| 3465383 | 109.4.1.1130 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_BSK1_C | 0.72 | 46.0 | 4.07e-01 | 94.1% | 45.5% |
| 4944462 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.72 | 47.0 | 4.68e-01 | 88.1% | 64.2% |
| 2392079 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.72 | 53.0 | 4.07e-01 | 77.1% | 39.9% |
| 3315458 | 109.4.1.198 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_12 | 0.72 | 52.0 | 4.29e-01 | 95.8% | 42.4% |
| 3740593 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.71 | 64.0 | 5.46e-01 | 96.6% | 67.6% |
| 4023646 | 174.1.1.88 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF7641 | 0.71 | 49.0 | 4.87e-01 | 75.4% | 67.2% |
| 3912535 | 603.2.1.1 ↗ | alpha bundles › STAT-like › STAT › STAT › STAT_alpha | 0.71 | 64.0 | 5.35e-01 | 97.5% | 85.1% |
| 5020412 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.70 | 46.0 | 4.90e-01 | 74.6% | 75.2% |
| 3662289 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.70 | 62.0 | 3.91e-01 | 98.3% | 28.0% |
| 4258378 | 3758.1.1.0 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins | 0.69 | 53.0 | 4.06e-01 | 81.4% | 74.4% |
| 3425427 | 4121.1.1.6 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › DUF155 | 0.69 | 53.0 | 4.13e-01 | 81.4% | 43.5% |
| 3358939 | 604.3.1.11 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › DUF155 | 0.69 | 53.0 | 4.10e-01 | 81.4% | 44.6% |
| 1719259 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.69 | 64.0 | 5.20e-01 | 99.2% | 68.6% |
| 5076274 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.69 | 52.0 | 4.58e-01 | 95.8% | 54.7% |
| 3736606 | 3924.1.1.0 ↗ | alpha complex topology › Sterol uptake control protein 2 › Sterol uptake control protein 2 › Sterol uptake control protein 2 | 0.68 | 60.0 | 5.13e-01 | 94.1% | 67.0% |
| 3865100 | 109.4.1.368 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SHNi-TPR | 0.67 | 57.0 | 4.26e-01 | 92.4% | 38.0% |
| 3491432 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.67 | 50.0 | 4.47e-01 | 81.4% | 55.8% |
| 3898996 | 109.4.1.219 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TINF2_N | 0.67 | 50.0 | 4.22e-01 | 91.5% | 46.5% |
| 4021431 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.65 | 47.0 | 4.48e-01 | 76.3% | 70.0% |
| 3871945 | 1147.1.1.6 ↗ | alpha bundles › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › MARVEL | 0.64 | 48.0 | 4.43e-01 | 78.8% | 61.3% |
| 3194235 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.64 | 47.0 | 5.12e-01 | 96.6% | 94.7% |
| 3705859 | 109.4.1.1315 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_7, TPR_8, TPR_10, TPR_12 | 0.64 | 57.0 | 4.58e-01 | 98.3% | 51.1% |
| 3696316 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.64 | 55.0 | 5.10e-01 | 93.2% | 78.0% |
| 4014490 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.64 | 45.0 | 3.54e-01 | 90.7% | 32.8% |
| 3640303 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.63 | 55.0 | 4.99e-01 | 95.8% | 86.9% |
| 3537779 | 192.29.1.19 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon | 0.63 | 48.0 | 4.31e-01 | 78.8% | 81.2% |
| 3929825 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.63 | 45.0 | 4.48e-01 | 76.3% | 71.7% |
| 3517687 | 601.1.2.4 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_R4 | 0.63 | 48.0 | 4.60e-01 | 83.1% | 68.6% |
| 3259335 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.63 | 45.0 | 3.61e-01 | 75.4% | 54.8% |
| 5075988 | 150.1.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Ferritin | 0.62 | 48.0 | 4.37e-01 | 81.4% | 96.9% |
| 3485310 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.62 | 43.0 | 4.08e-01 | 76.3% | 60.0% |
| 4944402 | 150.1.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Ferritin | 0.62 | 48.0 | 4.34e-01 | 83.1% | 92.1% |
| 3543912 | 109.4.1.1352 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › EFR3_ARM, EFR3 | 0.61 | 55.0 | 4.45e-01 | 98.3% | 63.6% |
| 3881492 | 109.4.1.411 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TTC3_DZIP3_dom | 0.61 | 44.0 | 3.28e-01 | 95.8% | 28.4% |
| 3260766 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 45.0 | 4.25e-01 | 95.8% | 65.0% |
| 3743087 | 109.4.1.1307 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps52_CC, Vps52_C | 0.60 | 51.0 | 3.69e-01 | 98.3% | 45.4% |
| 3737813 | 7087.1.1.1 ↗ | alpha bundles › Emopamil binding protein (EBP) transmembrane domain › Emopamil binding protein (EBP) transmembrane domain › Emopamil binding protein (EBP) transmembrane domain › EBP | 0.58 | 42.0 | 3.88e-01 | 78.0% | 58.1% |
| 3579643 | 109.7.1.6 ↗ | alpha superhelices › Repetitive alpha hairpins › Cytochrome c oxidase subunit E › Cytochrome c oxidase subunit E › TRAPPC9-Trs120 | 0.58 | 49.0 | 5.03e-01 | 97.5% | 95.7% |
| 4068006 | 3755.3.1.295 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › WWC1 | 0.57 | 51.0 | 4.66e-01 | 97.5% | 83.9% |
| 4977008 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 48.0 | 4.05e-01 | 97.5% | 55.0% |
| 4023130 | 109.4.1.356 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans | 0.55 | 50.0 | 4.04e-01 | 100.0% | 88.0% |
| 5057379 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.55 | 47.0 | 4.67e-01 | 91.5% | 94.2% |
| 3499614 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 47.0 | 3.44e-01 | 98.3% | 39.4% |
| 3657047 | 174.1.1.57 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › ABCC10_N | 0.54 | 47.0 | 4.11e-01 | 94.1% | 85.7% |
| 3356479 | 192.29.1.48 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Chloroplast_duf | 0.53 | 47.0 | 3.48e-01 | 99.2% | 96.2% |
| 3829175 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.52 | 36.0 | 3.58e-01 | 70.3% | 76.7% |
| 3713451 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.50 | 43.0 | 4.19e-01 | 91.5% | 92.3% |
D3
medium
residues 308-384_409-460
Domain cluster:
representative
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4e6nA02 | 6.10.140.1010 | Special › Helix non-globular › Helix Hairpins › | 0.72 | 22.0 | 3.17e-01 | 88.4% | 56.1% |
| 2pmrA00 | 1.20.1270.90 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like | 0.70 | 22.0 | 2.90e-01 | 76.7% | 47.4% |
| 5jazA03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.58 | 27.0 | 3.25e-01 | 80.6% | 64.8% |
| 4nooB00 | 1.10.8.1160 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.58 | 39.0 | 4.57e-01 | 88.4% | 94.7% |
| 3crmA02 | 1.10.287.890 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Crystal structure of tRNA isopentenylpyrophosphate transferase (bh2366) domain | 0.52 | 29.0 | 3.62e-01 | 80.6% | 85.7% |
ECOD (2)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4275437 | 5063.1.1.12 ↗ | alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › ApoO | 0.68 | 23.0 | 3.34e-01 | 74.4% | 63.3% |
| 3590136 | 162.1.1.1 ↗ | alpha bundles › PTS-regulatory domain, PRD › PTS-regulatory domain, PRD › PTS-regulatory domain, PRD › PRD | 0.51 | 25.0 | 2.68e-01 | 82.9% | 52.7% |