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CAKLQF020000014.1__CAH1087084.1__SAMEA5780031_02582__00003

Bact-Vir

CAKLQF020000014.1__CAH1087084.1__SAMEA5780031_02582__00003

Identity

Kingdom:
phage

Quality

86.4 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 5-221
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF13643.12 best DUF4145 45.2 1.10e-11 44.2% 93.2%
CATH (11)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2q00B00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.78 44.0 5.89e-01 95.4% 100.0%
4nqfA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.72 44.0 5.35e-01 96.8% 90.3%
4p9fA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.68 31.0 3.76e-01 97.7% 63.9%
7ae2A01 1.20.120.580 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like 0.67 42.0 5.26e-01 94.5% 99.3%
1ylmA00 1.20.120.580 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like 0.67 43.0 5.21e-01 92.6% 97.2%
1z23A00 1.20.120.830 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain 0.60 38.0 4.35e-01 97.2% 84.7%
3l0iA01 1.20.120.1520 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.55 42.0 4.66e-01 94.9% 97.2%
1hw1A02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.55 31.0 3.69e-01 84.8% 79.5%
3o6xA02 1.20.120.1560 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.52 30.0 3.61e-01 85.7% 82.4%
1bf5A01 1.20.1050.20 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain 0.52 28.0 3.24e-01 74.7% 69.6%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.50 32.0 3.56e-01 76.5% 79.2%
ECOD (33)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3988609 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.90 64.0 7.44e-01 97.7% 97.5%
5084064 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.86 46.0 6.30e-01 97.7% 96.7%
4996239 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.85 48.0 5.99e-01 94.9% 86.4%
5031744 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.85 46.0 6.18e-01 95.9% 94.4%
3602540 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.85 47.0 6.05e-01 94.5% 89.6%
5031827 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.84 47.0 6.03e-01 95.9% 90.4%
4950656 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.84 47.0 6.06e-01 95.9% 92.3%
4340320 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.83 45.0 6.03e-01 94.5% 93.6%
5050149 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.83 48.0 6.23e-01 95.9% 95.4%
4183373 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.83 46.0 6.10e-01 94.0% 95.2%
5041344 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.83 45.0 5.91e-01 94.5% 91.4%
4948130 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.82 47.0 6.02e-01 96.8% 91.9%
4969920 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.82 46.0 5.91e-01 94.0% 92.3%
4970321 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.81 47.0 6.11e-01 96.3% 96.2%
5035117 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.81 47.0 5.74e-01 97.2% 86.1%
5077650 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.81 47.0 6.06e-01 95.9% 95.4%
4938272 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.81 45.0 5.88e-01 93.1% 94.4%
5054502 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.81 38.0 5.69e-01 87.1% 100.0%
4937573 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.81 43.0 5.46e-01 95.4% 84.4%
5028077 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.80 39.0 5.55e-01 87.6% 94.5%
5079372 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.79 44.0 5.97e-01 94.9% 100.0%
5052086 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.78 44.0 5.72e-01 95.9% 93.8%
4932808 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.77 39.0 5.41e-01 86.6% 93.9%
4993305 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.77 44.0 5.75e-01 92.6% 95.4%
5051989 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.77 46.0 5.85e-01 95.9% 96.3%
4969330 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.76 44.0 5.68e-01 94.9% 96.1%
4928443 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.76 43.0 5.48e-01 94.5% 93.0%
5031415 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.74 45.0 5.58e-01 94.5% 93.5%
5064674 601.7.1.1 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like 0.74 42.0 5.60e-01 93.5% 100.0%
5032549 601.7.1.1 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like 0.74 44.0 5.60e-01 94.9% 98.5%
4950924 601.7.1.1 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like 0.70 44.0 5.38e-01 94.5% 95.2%
5078378 601.7.1.1 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like 0.64 40.0 4.75e-01 93.5% 92.4%
4567743 601.14.1.0 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin 0.57 37.0 4.04e-01 92.2% 78.3%
D2 high residues 230-356
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF13588.13 best HSDR_N_2 27.7 3.30e-06 85.8% 85.5%
PF04313.21 HSDR_N 33.4 5.80e-08 67.7% 39.5%
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3h1tA01 3.90.1570.30 Alpha Beta › Alpha-Beta Complex › tt1808, chain A › 0.84 81.0 7.88e-01 100.0% 95.6%
2w00A01 3.90.1570.50 Alpha Beta › Alpha-Beta Complex › tt1808, chain A › 0.69 64.0 5.73e-01 100.0% 84.2%
3l0aA00 3.90.320.10 Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › 0.68 56.0 4.31e-01 85.8% 58.6%
3ijmA00 3.90.1570.20 Alpha Beta › Alpha-Beta Complex › tt1808, chain A › 0.66 58.0 5.60e-01 95.3% 82.9%
3ot2A00 3.90.1570.10 Alpha Beta › Alpha-Beta Complex › tt1808, chain A › tt1808, chain A 0.66 58.0 5.18e-01 95.3% 77.7%
3n2qA02 3.30.300.190 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › 0.61 42.0 4.44e-01 70.9% 98.3%
5yrzB00 3.30.920.30 Alpha Beta › 2-Layer Sandwich › Metal Transport, Frataxin; Chain A › Hypothetical protein. 0.58 29.0 3.80e-01 89.8% 96.6%
2ot9A01 3.10.640.10 Alpha Beta › Roll › Restriction endonuclease-like alpha-beta roll fold › Restriction endonuclease-like alpha-beta roll domain 0.57 43.0 3.84e-01 89.8% 56.2%
3lyhA00 3.40.50.1400 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.56 41.0 4.21e-01 89.8% 80.0%
5aykA04 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.56 33.0 3.66e-01 97.6% 72.5%
2g9iA01 3.30.1330.100 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › CofE-like 0.56 45.0 4.43e-01 86.6% 96.4%
1s3aA00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.56 34.0 3.92e-01 99.2% 88.2%
1r26A00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.54 34.0 3.61e-01 100.0% 70.8%
2bfdB02 3.40.50.920 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.53 44.0 4.44e-01 95.3% 89.6%
4j07A00 3.40.50.960 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Lumazine/riboflavin synthase 0.53 47.0 4.47e-01 100.0% 84.9%
7xjrA01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.52 41.0 3.19e-01 83.5% 83.0%
2ymuA02 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.52 43.0 3.38e-01 90.6% 93.1%
2y27A02 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.52 36.0 3.97e-01 77.2% 88.3%
2nzxA02 3.40.50.11650 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycosyl transferase family 10, N-terminal domain 0.51 37.0 3.88e-01 99.2% 82.1%
3ihkA00 3.40.50.10240 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin pyrophosphokinase, catalytic domain 0.51 42.0 3.60e-01 89.0% 96.6%
1xqbA02 3.30.2310.10 Alpha Beta › 2-Layer Sandwich › YaeB-like fold › YaeB-like 0.50 23.0 2.83e-01 77.2% 67.1%
ECOD (56)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3988610 2008.1.1.15 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › HSDR_N 0.96 92.0 9.11e-01 100.0% 95.4%
4950210 2008.1.1.15 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › HSDR_N 0.92 90.0 8.36e-01 100.0% 94.7%
5018558 2008.1.1.162 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF30170 0.89 85.0 8.35e-01 98.4% 100.0%
4643516 2008.1.1.15 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › HSDR_N 0.86 83.0 7.63e-01 100.0% 85.8%
3988984 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.86 83.0 7.53e-01 100.0% 81.9%
4137732 2008.1.1.100 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › HSDR_N_2 0.85 82.0 7.67e-01 100.0% 90.0%
3386283 2008.1.1.100 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › HSDR_N_2 0.81 74.0 5.94e-01 95.3% 73.3%
4943352 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.77 61.0 4.61e-01 82.7% 65.4%
5022884 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.76 65.0 6.86e-01 94.5% 100.0%
3182836 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.76 71.0 6.33e-01 99.2% 92.4%
4536530 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.76 59.0 4.68e-01 81.1% 71.0%
3248549 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.75 70.0 6.04e-01 99.2% 79.5%
3386658 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.74 56.0 4.96e-01 78.7% 80.0%
4932253 2008.1.1.100 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › HSDR_N_2 0.73 67.0 6.42e-01 98.4% 97.2%
3255906 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.73 66.0 6.23e-01 97.6% 95.3%
4941120 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.71 66.0 5.95e-01 100.0% 86.5%
4950447 2008.1.1.87 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › YhcG_C 0.70 60.0 5.58e-01 90.6% 84.4%
4950791 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.69 56.0 5.00e-01 85.0% 75.4%
3279385 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.69 57.0 5.20e-01 89.0% 82.8%
5014788 2008.1.1.108 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF234 0.67 55.0 5.79e-01 90.6% 97.4%
5053352 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.67 61.0 5.63e-01 99.2% 98.1%
5018195 2008.1.1.87 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › YhcG_C 0.67 57.0 5.42e-01 90.6% 86.2%
4010728 2008.1.1.87 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › YhcG_C 0.66 55.0 5.43e-01 89.8% 88.9%
4960251 2008.1.1.16 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Mrr_cat 0.65 60.0 5.90e-01 99.2% 96.2%
4964370 2008.1.1.230 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF7527 0.65 55.0 4.50e-01 91.3% 97.9%
3838862 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.65 59.0 5.51e-01 96.9% 89.0%
5076295 2008.1.1.107 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › NERD 0.64 59.0 5.80e-01 100.0% 99.3%
4032115 2008.1.1.102 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF1829 0.63 55.0 5.65e-01 94.5% 100.0%
4009644 2008.1.1.160 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF27151 0.63 52.0 4.74e-01 89.8% 80.9%
2876025 5104.1.1.1 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 0.63 45.0 4.55e-01 74.0% 97.6%
4271425 2008.1.1.81 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF2726 0.63 56.0 5.19e-01 100.0% 76.2%
4352326 2008.1.1.81 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF2726 0.62 54.0 5.54e-01 96.9% 98.3%
5066103 5104.1.1.1 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 0.62 44.0 4.52e-01 74.0% 100.0%
5028573 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.62 52.0 5.04e-01 89.0% 95.0%
3964887 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.62 53.0 5.19e-01 92.9% 100.0%
4931728 2008.1.1.212 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF27326 0.61 53.0 4.84e-01 96.1% 91.2%
5030819 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.59 52.0 5.16e-01 96.9% 98.5%
5014287 327.11.1.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Prokaryotic type KH domain (KH-domain type II) 0.58 40.0 4.66e-01 78.7% 100.0%
5032419 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.57 50.0 4.32e-01 97.6% 88.3%
5083491 327.7.1.1 a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer 0.57 37.0 4.42e-01 74.0% 98.8%
4594294 327.7.1.1 a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer 0.57 37.0 4.21e-01 73.2% 88.4%
3412307 7585.1.1.0 a/b three-layered sandwiches › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins 0.56 49.0 4.61e-01 96.9% 100.0%
3408206 2007.1.2.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.55 48.0 4.44e-01 94.5% 100.0%
5038704 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.55 49.0 4.39e-01 100.0% 79.4%
3591987 2003.1.5.24 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Met_10 0.55 39.0 2.90e-01 74.8% 44.3%
3088276 2485.1.1.19 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › L51_S25_CI-B8 0.53 32.0 3.58e-01 100.0% 76.5%
3283842 2002.1.1.55 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_25 0.53 43.0 3.73e-01 88.2% 98.0%
3940255 2007.1.2.4 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ANF_receptor 0.53 46.0 3.95e-01 100.0% 92.7%
4013321 2485.1.1.19 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › L51_S25_CI-B8 0.52 30.0 3.44e-01 98.4% 75.5%
3243708 2008.1.1.27 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RAI1 0.52 41.0 3.09e-01 85.8% 41.2%
5039133 316.1.1.2 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 0.52 37.0 4.03e-01 74.8% 90.5%
4933321 316.1.1.2 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 0.51 38.0 3.60e-01 76.4% 78.7%
4994516 316.1.1.2 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 0.51 38.0 3.58e-01 77.2% 81.3%
5072488 316.1.1.2 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 0.50 37.0 4.02e-01 76.4% 94.2%
4042155 7520.1.1.1 a/b three-layered sandwiches › CinA-like › CinA-like › CinA-like › CinA 0.50 41.0 3.87e-01 88.2% 99.4%
3705514 212.1.1.4 a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › GHMP_kinases_N,GalKase_gal_bdg 0.50 41.0 3.42e-01 89.8% 85.4%
D3 high residues 381-558
PDB
Pfam (4)
AccessionNameScoreE-valueQ covHMM cov
PF18766.8 best SWI2_SNF2 71.1 1.50e-19 100.0% 80.5%
PF00270.36 DEAD 43.5 4.20e-11 86.0% 91.6%
PF04851.22 ResIII 119.0 2.80e-34 83.7% 93.3%
PF13245.13 AAA_19 25.2 2.30e-05 77.0% 68.7%
D4 high residues 564-585_622-773
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00271.38 best Helicase_C 27.4 4.60e-06 71.3% 86.4%
D5 medium residues 586-597_609-621_873-972
PDB
Domain cluster: representative
CATH (4)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5dqqA01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.66 48.0 4.85e-01 76.0% 94.5%
4ebjA02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.64 45.0 4.44e-01 70.4% 84.6%
1nzeA00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.62 47.0 4.90e-01 79.2% 97.3%
1q0gA00 1.20.120.400 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase 0.62 48.0 4.95e-01 81.6% 94.0%
ECOD (5)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3638493 601.16.1.0 alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase 0.76 54.0 4.95e-01 73.6% 85.6%
3246381 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.70 29.0 2.84e-01 70.4% 35.7%
3186741 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.62 45.0 3.66e-01 75.2% 68.1%
4946108 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.53 40.0 3.52e-01 80.0% 64.8%
3882568 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.51 39.0 3.32e-01 80.0% 60.5%
D6 medium residues 775-872
PDB
Domain cluster: representative
CATH (29)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1orjD00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.76 63.0 5.81e-01 88.8% 78.4%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.74 60.0 5.72e-01 88.8% 100.0%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.74 61.0 5.58e-01 89.8% 91.5%
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.72 60.0 5.67e-01 89.8% 93.3%
4adnA01 1.20.1280.250 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.72 54.0 5.81e-01 89.8% 91.8%
2lqgA00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.71 50.0 4.45e-01 72.4% 76.8%
3behB01 1.20.120.540 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels 0.69 57.0 5.40e-01 89.8% 88.9%
7ae2A01 1.20.120.580 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like 0.68 56.0 5.01e-01 88.8% 92.7%
1wrdA00 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 48.0 4.87e-01 73.5% 80.6%
1zzpA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.68 55.0 5.32e-01 87.8% 97.2%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.68 55.0 4.97e-01 88.8% 92.5%
2xzmO02 1.10.287.10 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding 0.67 45.0 5.15e-01 85.7% 98.6%
3kyiA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.67 56.0 5.07e-01 89.8% 79.7%
3ezhA00 1.20.120.960 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase NarX, sensor domain 0.67 55.0 5.23e-01 89.8% 89.5%
2p61A00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.65 52.0 4.98e-01 87.8% 87.7%
2au5A00 1.20.120.590 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › EF2947-like 0.62 54.0 4.99e-01 96.9% 93.8%
4od4A01 1.10.357.140 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › UbiA prenyltransferase 0.60 51.0 4.38e-01 92.9% 85.9%
2nn4A00 1.10.287.760 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YqgQ-like 0.60 33.0 3.90e-01 72.4% 80.6%
1zu2A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.59 44.0 3.77e-01 78.6% 77.2%
3pjaJ01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.59 42.0 3.81e-01 73.5% 59.5%
2y1vA04 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.59 43.0 3.54e-01 77.6% 49.7%
3zgzA04 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.58 47.0 3.87e-01 86.7% 56.5%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.58 41.0 3.96e-01 74.5% 85.5%
2qw6D00 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.57 43.0 4.48e-01 89.8% 90.7%
4iluA02 1.20.58.1290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain 0.56 43.0 4.13e-01 79.6% 87.4%
2np9A01 1.20.58.1300 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 43.0 3.93e-01 85.7% 85.1%
3ubkB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.53 37.0 3.49e-01 72.4% 56.8%
2pvqA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.52 43.0 4.22e-01 89.8% 91.5%
3ihvA03 1.25.40.900 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.50 40.0 3.63e-01 87.8% 77.7%
ECOD (20)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5010954 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.75 61.0 5.87e-01 87.8% 95.5%
3741700 109.40.1.2 alpha superhelices › Repetitive alpha hairpins › DNA polymerase alpha-binding protein Ctf4 C-terminal domain › DNA polymerase alpha-binding protein Ctf4 C-terminal domain › Ctf4_C 0.72 50.0 4.73e-01 71.4% 74.8%
3483038 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.69 51.0 4.68e-01 76.5% 68.8%
3332149 192.4.1.0 alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) 0.68 44.0 4.83e-01 80.6% 80.0%
3497347 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.68 56.0 5.22e-01 89.8% 88.0%
3593997 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.68 56.0 5.09e-01 89.8% 74.6%
3236850 601.55.1.0 alpha bundles › Four-helical up-and-down bundle › anti-complement domain of BBK32 › anti-complement domain of BBK32 0.67 53.0 5.24e-01 85.7% 89.5%
3444721 603.1.1.6 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin_2 0.66 48.0 3.80e-01 74.5% 48.7%
4034504 601.4.1.47 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › MspA_staph 0.65 54.0 5.28e-01 90.8% 99.0%
3723563 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.60 41.0 3.13e-01 99.0% 31.6%
3586442 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.60 42.0 4.10e-01 73.5% 73.6%
3266510 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.58 42.0 3.67e-01 74.5% 77.2%
3946272 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.55 40.0 3.35e-01 83.7% 44.2%
3667215 109.1.1.37 alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_N_2 0.54 43.0 3.43e-01 87.8% 53.5%
3254198 603.5.1.0 alpha bundles › STAT-like › FlgN-like › FlgN-like 0.53 44.0 3.61e-01 90.8% 67.0%
3429485 2485.1.1.0 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like 0.53 41.0 3.21e-01 83.7% 53.6%
3889202 109.1.1.6 alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_C_2 0.52 40.0 3.61e-01 82.7% 80.6%
3279499 109.4.1.1792 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF5682 0.52 39.0 3.18e-01 82.7% 72.0%
3299719 109.1.1.0 alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C 0.51 40.0 3.69e-01 83.7% 78.4%
4868274 188.1.1.1 alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep 0.50 39.0 3.26e-01 86.7% 92.0%
D7 medium residues 992-1146
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF08463.16 best EcoEI_R_C 78.5 8.50e-22 97.4% 96.9%
CATH (4)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3fnbA01 1.20.1440.110 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase 0.59 33.0 3.84e-01 90.3% 74.6%
2gz4A00 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.57 36.0 3.35e-01 78.7% 48.0%
2xi9A03 1.10.150.480 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.55 34.0 4.00e-01 91.6% 92.1%
3rlfG01 1.10.3720.10 Mainly Alpha › Orthogonal Bundle › MetI-like fold › MetI-like 0.51 33.0 2.81e-01 91.0% 36.6%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5018561 101.1.1.381 alpha arrays › HTH › HTH › Three-helical HTH › EcoEI_R_C 0.72 40.0 5.25e-01 85.8% 100.0%
3605549 108.1.1.0 alpha arrays › EF-hand › EF-hand-related › EF-hand 0.61 33.0 3.92e-01 79.4% 78.0%
4029967 633.1.1.0 alpha bundles › Bromodomain-like › Bromodomain › Bromodomain 0.58 38.0 4.31e-01 75.5% 87.8%
4943090 5045.1.1.3 alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › V_ATPase_I 0.55 38.0 3.06e-01 72.3% 46.9%