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CAKLQF020000015.1__CAH1087430.1__SAMEA5780031_02682__00003

Bact-Vir

CAKLQF020000015.1__CAH1087430.1__SAMEA5780031_02682__00003

Identity

Kingdom:
phage

Quality

92.4 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 43-267
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF00753.34 best Lactamase_B 51.5 1.80e-13 79.1% 80.1%
PF12706.14 Lactamase_B_2 29.8 6.10e-07 59.1% 70.0%
CATH (42)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1m2xA00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.86 74.0 7.59e-01 89.3% 92.7%
2qdsA00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.84 74.0 7.43e-01 89.8% 94.6%
1a7tA00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.84 76.0 7.64e-01 99.6% 92.5%
1vmeB01 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.84 74.0 7.07e-01 90.7% 95.2%
3pg4A00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.83 72.0 7.19e-01 89.3% 91.3%
1dxkA00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.83 75.0 7.61e-01 99.6% 95.5%
1ko2A00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.82 76.0 7.60e-01 100.0% 93.9%
6v54A00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.82 70.0 7.27e-01 90.7% 93.9%
2zo4A01 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.82 69.0 6.62e-01 87.1% 92.5%
2p18A00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.82 72.0 6.52e-01 90.2% 88.3%
2q9uB01 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.82 70.0 6.83e-01 89.3% 95.1%
1wuoA00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.82 71.0 7.19e-01 90.7% 91.8%
4ad9A01 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.82 72.0 7.53e-01 92.4% 100.0%
1xm8A00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.81 68.0 6.46e-01 85.8% 83.9%
2xf4A00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.80 67.0 6.95e-01 85.8% 95.2%
6t5kC00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.80 73.0 7.40e-01 96.9% 95.5%
6u10A00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.80 71.0 6.58e-01 91.6% 87.0%
2cfuA01 3.60.15.30 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Metallo-beta-lactamase domain 0.79 76.0 6.37e-01 100.0% 84.6%
1k07A00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.79 70.0 6.58e-01 91.1% 90.8%
2zwrB00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.79 66.0 6.86e-01 85.8% 92.8%
6dq2A00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.79 69.0 6.60e-01 91.1% 90.3%
6n36A00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.79 70.0 6.54e-01 91.6% 89.8%
3adrB00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.79 66.0 6.25e-01 85.8% 82.4%
5wcmA00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.78 69.0 6.55e-01 92.4% 91.3%
2q0iA00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.77 74.0 6.57e-01 100.0% 78.0%
1ztcA00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.75 63.0 6.56e-01 86.2% 99.0%
3r2uB01 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.74 65.0 6.21e-01 98.2% 81.0%
4awyB00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.74 71.0 6.59e-01 100.0% 92.6%
6j4nC01 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.74 61.0 5.22e-01 85.8% 78.6%
3zwfA00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.71 58.0 5.54e-01 84.4% 96.5%
1y44A00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.71 59.0 5.51e-01 85.3% 93.7%
7t28A01 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.71 58.0 5.74e-01 84.0% 98.3%
1zkpC00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.71 59.0 5.74e-01 86.2% 93.9%
3md7A00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.65 61.0 5.66e-01 98.2% 95.2%
2p4zA00 3.60.15.10 Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 0.61 57.0 5.26e-01 98.2% 93.8%
5ybwA02 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.59 28.0 4.02e-01 77.8% 100.0%
4wesB04 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.56 27.0 3.80e-01 74.7% 100.0%
2zj3A02 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.54 31.0 3.65e-01 89.8% 81.1%
6p3xB01 3.40.140.10 Alpha Beta › 3-Layer(aba) Sandwich › Cytidine Deaminase; domain 2 › Cytidine Deaminase, domain 2 0.53 33.0 3.62e-01 74.7% 76.3%
4evqA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 33.0 3.82e-01 81.3% 86.7%
4q6bA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 31.0 3.87e-01 73.8% 97.0%
3r4vA01 3.40.50.1440 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Tubulin/FtsZ, GTPase domain 0.52 39.0 3.61e-01 78.2% 92.8%
ECOD (87)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4167076 247.1.1.0 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase 0.90 77.0 6.97e-01 90.7% 67.9%
4531960 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.89 75.0 6.86e-01 89.8% 69.1%
5013541 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.87 76.0 7.69e-01 90.2% 97.8%
4583096 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.85 75.0 7.42e-01 90.2% 88.0%
5048511 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.85 73.0 7.39e-01 88.4% 93.8%
4946931 247.1.1.0 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase 0.85 73.0 7.01e-01 88.0% 93.2%
5049876 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.85 74.0 7.19e-01 89.8% 92.6%
4978518 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.85 74.0 7.37e-01 90.2% 94.8%
5065327 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.84 76.0 6.73e-01 92.4% 78.3%
424209 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.84 73.0 7.33e-01 89.8% 93.9%
5008621 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.84 69.0 7.32e-01 98.7% 94.5%
4977109 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.84 71.0 7.24e-01 87.1% 96.4%
4990171 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.84 72.0 6.50e-01 88.9% 76.6%
5072010 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.84 72.0 6.20e-01 88.0% 77.8%
3955441 247.1.1.24 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B+Lactamase_B_2 0.83 74.0 7.08e-01 92.4% 94.9%
3988451 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.83 70.0 7.22e-01 86.2% 96.7%
4993443 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.83 71.0 7.18e-01 88.0% 94.1%
3709411 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.82 72.0 6.08e-01 90.7% 81.3%
4962825 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.82 71.0 7.27e-01 88.9% 93.0%
166678 247.1.1.15 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › HAGH_C 0.82 72.0 6.52e-01 90.2% 88.3%
5043109 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.81 69.0 7.07e-01 88.0% 91.4%
5010017 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.81 68.0 6.92e-01 86.2% 95.5%
5053488 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.81 75.0 6.76e-01 96.0% 77.6%
4944220 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.81 71.0 6.44e-01 91.1% 86.2%
4945132 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.81 67.0 7.05e-01 85.8% 97.6%
4981939 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.80 67.0 6.42e-01 86.2% 79.6%
5026347 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.80 68.0 7.19e-01 86.7% 100.0%
2531407 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.80 74.0 6.73e-01 96.0% 90.9%
4223372 247.1.1.5 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B,HAGH_C 0.80 68.0 6.44e-01 86.2% 83.9%
4955241 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.80 70.0 7.23e-01 89.8% 97.1%
4930600 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.80 66.0 6.92e-01 84.4% 95.6%
2527260 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.80 71.0 6.58e-01 91.6% 87.0%
2770859 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.79 70.0 6.55e-01 91.1% 86.1%
3965918 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.79 66.0 6.98e-01 86.2% 96.6%
3699020 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.79 71.0 6.39e-01 94.2% 89.0%
2499514 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.79 69.0 6.41e-01 91.1% 85.8%
3839913 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.79 65.0 6.92e-01 85.3% 96.0%
3641983 247.1.1.0 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase 0.78 68.0 6.01e-01 89.3% 72.1%
4986849 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.78 70.0 6.72e-01 92.4% 86.8%
4998818 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.78 75.0 6.39e-01 99.1% 71.6%
4119933 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.77 66.0 6.26e-01 88.4% 78.8%
5083484 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.75 72.0 6.87e-01 100.0% 96.1%
3364518 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.75 69.0 6.12e-01 98.7% 70.0%
4982215 247.1.1.11 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2 0.75 62.0 5.93e-01 85.8% 90.2%
4089853 247.1.1.31 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_4, Anti-Pycsar_Apyc1 0.73 59.0 5.26e-01 84.4% 95.5%
4382195 247.1.1.31 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_4, Anti-Pycsar_Apyc1 0.73 59.0 5.22e-01 84.4% 95.9%
3427768 101.1.2.160 alpha arrays › HTH › HTH › winged helix domain › BLACT_WH 0.73 68.0 5.94e-01 98.2% 68.6%
None 0.73 59.0 5.29e-01 84.4% 97.4%
4976682 247.1.1.0 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase 0.73 60.0 4.61e-01 86.2% 89.5%
5069926 247.1.1.11 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2 0.73 60.0 5.39e-01 86.2% 94.1%
3509040 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.72 62.0 5.85e-01 89.8% 79.6%
4350189 247.1.1.29 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2, Anti-Pycsar_Apyc1 0.72 60.0 5.25e-01 85.8% 91.3%
4170217 247.1.1.33 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B, Lactamase_B_2, Anti-Pycsar_Apyc1 0.72 60.0 5.28e-01 85.8% 94.6%
4331327 247.1.1.29 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2, Anti-Pycsar_Apyc1 0.72 60.0 5.35e-01 86.2% 93.1%
4434849 247.1.1.24 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B+Lactamase_B_2 0.72 60.0 5.35e-01 86.2% 93.4%
4995525 247.1.1.30 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Anti-Pycsar_Apyc1 0.72 60.0 5.28e-01 86.2% 90.5%
3781318 247.1.1.7 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › PDEase_II 0.72 60.0 4.96e-01 86.2% 97.1%
4946355 247.1.1.0 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase 0.72 59.0 5.29e-01 86.2% 92.9%
4941343 247.1.1.11 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2 0.72 59.0 5.39e-01 86.2% 95.2%
4252853 247.1.1.29 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2, Anti-Pycsar_Apyc1 0.71 59.0 5.33e-01 85.8% 95.0%
5012764 247.1.1.30 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Anti-Pycsar_Apyc1 0.71 59.0 5.27e-01 86.2% 92.9%
5050510 247.1.1.30 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Anti-Pycsar_Apyc1 0.71 59.0 5.13e-01 85.8% 95.7%
5078955 247.1.1.11 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2 0.71 59.0 5.71e-01 85.8% 93.5%
5024426 247.1.1.11 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2 0.71 59.0 5.63e-01 86.2% 86.6%
4429651 247.1.1.29 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2, Anti-Pycsar_Apyc1 0.69 58.0 5.32e-01 86.2% 95.7%
4053783 247.1.1.33 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B, Lactamase_B_2, Anti-Pycsar_Apyc1 0.69 57.0 5.23e-01 86.2% 95.2%
4107278 247.1.1.0 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase 0.69 57.0 5.40e-01 85.8% 96.5%
3442876 247.1.1.11 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2 0.67 62.0 5.61e-01 97.3% 91.5%
5048021 247.1.1.11 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2 0.67 62.0 6.07e-01 97.8% 99.6%
4993687 247.1.1.11 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2 0.66 58.0 5.72e-01 92.4% 94.2%
3438266 247.1.1.11 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2 0.65 60.0 5.66e-01 97.3% 95.2%
4070827 247.1.1.12 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_3 0.65 54.0 5.35e-01 85.8% 91.9%
4665964 247.1.1.0 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase 0.65 54.0 5.35e-01 85.8% 91.9%
4265111 247.1.1.11 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2 0.65 54.0 5.39e-01 85.8% 93.0%
412628 247.1.1.11 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2 0.65 60.0 5.64e-01 98.2% 95.2%
5036303 247.1.1.11 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2 0.64 59.0 5.35e-01 98.2% 95.3%
4029956 247.1.1.16 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_6 0.64 59.0 5.27e-01 97.3% 94.7%
4999677 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.63 57.0 5.28e-01 97.3% 93.7%
5071241 247.1.1.11 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2 0.62 58.0 5.52e-01 98.7% 94.9%
167333 247.1.1.24 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B+Lactamase_B_2 0.61 56.0 5.28e-01 97.3% 95.9%
5043594 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.61 54.0 5.45e-01 97.8% 91.7%
4936643 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.61 56.0 5.13e-01 97.3% 99.3%
4989119 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.61 56.0 5.24e-01 98.2% 93.8%
5022432 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.61 49.0 5.18e-01 97.8% 92.6%
3603058 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.60 56.0 5.40e-01 98.7% 96.1%
5016814 247.1.1.11 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2 0.60 56.0 5.29e-01 97.3% 95.4%
5011868 246.2.1.1 a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos 0.53 43.0 4.40e-01 85.8% 90.9%
D2 high residues 272-352
PDB
Domain cluster: representative
CATH (27)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7dg2C01 1.10.10.1200 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › MAGE homology domain, winged helix WH1 motif 0.64 44.0 4.61e-01 98.8% 77.3%
3s64A00 1.10.225.10 Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like 0.64 47.0 4.75e-01 98.8% 79.0%
2c5zA00 1.10.1740.100 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Set2, Rpb1 interacting domain 0.63 43.0 4.17e-01 71.6% 63.4%
8gf5C01 3.30.70.470 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 53.0 4.46e-01 97.5% 84.5%
1u84A00 1.10.340.20 Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › Apc36109-like domain 0.60 44.0 4.48e-01 100.0% 80.2%
1aorA03 1.10.599.10 Mainly Alpha › Orthogonal Bundle › Aldehyde Ferredoxin Oxidoreductase Protein, subunit A; domain 3 › Aldehyde Ferredoxin Oxidoreductase Protein, subunit A, domain 3 0.60 47.0 3.56e-01 86.4% 72.0%
4n81A01 3.30.540.10 Alpha Beta › 2-Layer Sandwich › Fructose-1,6-Bisphosphatase; Chain A, domain 1 › Fructose-1,6-Bisphosphatase, subunit A, domain 1 0.58 50.0 4.34e-01 100.0% 86.0%
2ddhA01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.58 43.0 3.83e-01 92.6% 54.2%
4iu9B02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.57 49.0 3.79e-01 100.0% 79.8%
2o5iN07 1.10.132.30 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › RNA polymerase Rpb1 funnel domain 0.57 50.0 4.45e-01 97.5% 95.7%
2c42A03 3.40.920.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 0.56 38.0 2.93e-01 100.0% 27.8%
3ztaA00 1.10.490.130 Mainly Alpha › Orthogonal Bundle › Globin-like › 0.55 43.0 3.63e-01 85.2% 79.9%
3o60A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 44.0 3.42e-01 95.1% 39.0%
1gcvA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.54 46.0 3.94e-01 98.8% 93.6%
2ig3A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.54 43.0 3.74e-01 87.7% 85.8%
1lkvX02 1.10.220.30 Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Flagellar motor switch protein FliG, alpha-alpha superhelical domain 0.54 37.0 3.24e-01 71.6% 87.9%
3c7mA00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.54 37.0 2.81e-01 71.6% 42.1%
5gj7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.54 42.0 3.41e-01 84.0% 72.2%
1h99A02 1.10.1790.10 Mainly Alpha › Orthogonal Bundle › PTS-regulatory domain, PRD › PRD domain 0.53 46.0 4.29e-01 98.8% 93.4%
1ldjA01 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.53 43.0 3.77e-01 88.9% 93.6%
1a00B00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.53 44.0 3.67e-01 93.8% 86.3%
3m9vA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.52 40.0 3.23e-01 82.7% 69.4%
2b1eA02 1.20.1310.30 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › 0.52 41.0 3.51e-01 96.3% 49.7%
1li5A02 1.20.120.640 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.51 39.0 3.84e-01 96.3% 75.9%
3lcnB00 1.10.340.40 Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › Nuclear abundant poly(A) RNA-bind protein 2, N-terminal domain 0.51 37.0 3.61e-01 100.0% 68.0%
2wy4A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.51 43.0 3.72e-01 100.0% 92.1%
2c0kB00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.51 43.0 3.63e-01 100.0% 94.6%
ECOD (22)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3725613 101.1.6.0 alpha arrays › HTH › HTH › TrpR 0.72 58.0 5.31e-01 86.4% 65.7%
3615624 101.11.1.0 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 0.64 57.0 5.25e-01 100.0% 91.4%
5053783 5082.1.1.0 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like 0.61 43.0 3.52e-01 72.8% 40.7%
4100017 210.1.3.3 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_4 0.61 43.0 3.06e-01 81.5% 22.2%
3666876 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.60 48.0 4.18e-01 87.7% 73.1%
3739207 5069.1.3.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.60 52.0 4.95e-01 97.5% 93.7%
4967801 3921.1.1.1 alpha complex topology › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › Rnf-Nqr 0.60 52.0 4.08e-01 100.0% 57.8%
5054557 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.59 51.0 5.00e-01 98.8% 94.4%
3505448 106.1.1.10 alpha arrays › Globin-like › Globin-like › Globin-like › BCD_RFX 0.59 48.0 3.95e-01 90.1% 76.7%
5043629 601.7.1.34 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › DUF4129 0.58 34.0 3.37e-01 70.4% 53.6%
5052279 632.1.1.2 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › BE_C 0.57 41.0 3.62e-01 75.3% 77.5%
3735029 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.56 51.0 4.32e-01 100.0% 86.9%
3510536 138.1.1.5 alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA_pol3_gamma3 0.56 39.0 3.47e-01 72.8% 60.0%
3518177 106.1.1.1 alpha arrays › Globin-like › Globin-like › Globin-like › Globin 0.55 45.0 3.64e-01 95.1% 90.9%
3822 604.4.1.1 alpha bundles › Spectrin repeat-like › Alpha-hemoglobin stabilizing protein AHSP › Alpha-hemoglobin stabilizing protein AHSP › AHSP 0.54 46.0 4.48e-01 98.8% 87.8%
4977883 6058.1.1.0 alpha arrays › C-terminal alpha domain in Alpha-Glycerophosphate Oxidase › C-terminal alpha domain in Alpha-Glycerophosphate Oxidase › C-terminal alpha domain in Alpha-Glycerophosphate Oxidase 0.54 43.0 3.56e-01 98.8% 50.0%
3242453 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.52 41.0 3.12e-01 87.7% 79.5%
3249527 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.52 41.0 3.46e-01 84.0% 89.6%
3386846 5067.1.1.1 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ACR_tran 0.52 38.0 2.87e-01 77.8% 41.4%
3682123 5050.1.1.2 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 0.51 42.0 3.21e-01 91.4% 98.0%
3969675 532.2.1.1 alpha arrays › Type III secretion system domain-like › Type III secretion system domains › Type III secretion system domains › HrpJ 0.51 39.0 3.60e-01 85.2% 82.7%
5044572 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.50 42.0 3.92e-01 93.8% 87.6%