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CAKLQF020000015.1__CAH1087457.1__SAMEA5780031_02695__00016

Bact-Vir

CAKLQF020000015.1__CAH1087457.1__SAMEA5780031_02695__00016

Identity

Kingdom:
phage

Quality

92.6 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 305-426
PDB
Domain cluster: representative
CATH (24)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5oklA01 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.63 39.0 4.28e-01 77.0% 75.2%
4mndA02 1.20.120.1760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain 0.62 44.0 3.82e-01 73.0% 49.2%
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 37.0 3.44e-01 76.2% 46.1%
1xioA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.59 49.0 4.06e-01 89.3% 84.3%
1o5hA00 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.57 39.0 3.34e-01 82.8% 42.0%
1xl3C00 1.20.1280.80 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.57 40.0 4.45e-01 77.0% 96.7%
7zh0A01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.56 46.0 3.24e-01 88.5% 78.0%
4bemJ00 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.56 40.0 3.57e-01 75.4% 55.2%
2zopA00 1.10.520.30 Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › AF1862-like domain 0.55 38.0 3.99e-01 86.1% 77.7%
3tuiA00 1.10.3720.10 Mainly Alpha › Orthogonal Bundle › MetI-like fold › MetI-like 0.55 49.0 4.07e-01 98.4% 81.9%
6xpdA01 1.20.1510.10 Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain 0.55 48.0 4.16e-01 100.0% 93.6%
2o36A01 1.20.1050.40 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Endopeptidase. Chain P; domain 1 0.54 37.0 3.73e-01 72.1% 81.2%
2wglA00 1.10.4190.10 Mainly Alpha › Orthogonal Bundle › Urease accessory protein UreF › Urease accessory protein UreF 0.53 45.0 3.71e-01 89.3% 53.6%
2pihA00 1.20.1500.10 Mainly Alpha › Up-down Bundle › YheA-like fold › YheA/YmcA-like 0.52 33.0 3.33e-01 94.3% 61.8%
2id6A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 45.0 4.18e-01 95.9% 84.4%
3vnxA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.52 41.0 3.58e-01 86.1% 84.6%
1rtwB00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.52 43.0 3.64e-01 90.2% 87.0%
1vi0A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 46.0 4.40e-01 100.0% 89.7%
2l7nA00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.51 44.0 4.05e-01 98.4% 74.4%
3vprA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.51 45.0 4.32e-01 99.2% 86.9%
5u1aL00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.51 42.0 3.90e-01 91.8% 98.8%
1pw4A01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.50 41.0 3.47e-01 88.5% 62.2%
1ic8A01 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.50 28.0 3.12e-01 100.0% 67.0%
8gy0A01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.50 43.0 3.39e-01 96.7% 56.6%
ECOD (33)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3988675 3355.1.1.29 alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS, MatC_N 0.96 93.0 6.02e-01 100.0% 28.3%
4582471 3355.1.1.11 alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › GntP_permease 0.87 80.0 5.25e-01 100.0% 26.9%
5083192 3355.1.1.11 alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › GntP_permease 0.86 81.0 5.67e-01 100.0% 36.1%
5067334 3355.1.1.2 alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS 0.85 80.0 5.45e-01 100.0% 31.9%
5078663 3355.1.1.8 alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_H_antiporter 0.81 76.0 5.05e-01 100.0% 28.9%
4230575 3355.1.1.16 alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › DcuC 0.78 73.0 4.79e-01 100.0% 91.8%
None 0.75 69.0 4.60e-01 100.0% 27.0%
3788506 6155.1.1.2 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.57 45.0 4.21e-01 84.4% 85.3%
4407611 3896.1.2.1 alpha duplicates or obligate multimers › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-archaeol synthase › CarS-like 0.57 46.0 4.10e-01 88.5% 81.7%
4177736 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.56 42.0 3.51e-01 77.9% 85.7%
3516872 4006.1.1.4 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › TraG_N 0.56 42.0 3.59e-01 77.9% 55.0%
3954266 1075.3.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 0.56 46.0 3.43e-01 88.5% 50.0%
3261141 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 48.0 3.90e-01 90.2% 56.4%
4977979 1075.1.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.56 49.0 4.01e-01 98.4% 77.9%
3243805 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.56 50.0 4.04e-01 100.0% 93.8%
3598319 1075.1.2.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain 0.55 42.0 3.59e-01 80.3% 89.2%
3974771 1075.1.2.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain 0.55 39.0 3.30e-01 100.0% 42.9%
5040617 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.55 42.0 3.56e-01 80.3% 91.3%
3268174 5050.1.1.4 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nucleoside_tran 0.54 43.0 3.52e-01 84.4% 80.9%
4966166 5038.2.1.12 alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like › TrbL_3 0.54 48.0 4.13e-01 100.0% 91.5%
4242856 5050.1.1.14 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › ATG22 0.53 44.0 3.32e-01 87.7% 61.1%
3176627 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.53 43.0 3.60e-01 90.2% 63.6%
3176246 5050.1.1.14 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › ATG22 0.53 46.0 3.53e-01 92.6% 60.4%
3184203 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.53 44.0 3.79e-01 92.6% 69.3%
5001269 1075.3.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold 0.52 47.0 3.98e-01 100.0% 83.4%
3282027 1075.3.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 0.52 47.0 3.87e-01 100.0% 70.5%
5014001 177.1.1.1 alpha bundles › Phospholipase C/P1 nuclease › Phospholipase C/P1 nuclease › Phospholipase C/P1 nuclease › Zn_dep_PLPC 0.52 42.0 3.39e-01 87.7% 83.7%
4505260 376.1.1.0 few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box 0.52 37.0 3.28e-01 77.0% 49.7%
3213370 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 42.0 3.48e-01 89.3% 56.4%
4951081 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 42.0 3.63e-01 89.3% 63.1%
3251840 601.1.3.6 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 › Talin_IBS2B 0.51 44.0 4.13e-01 100.0% 78.8%
3392606 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.50 41.0 3.40e-01 89.3% 56.9%
3829426 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.50 40.0 3.37e-01 88.5% 58.2%
D2 medium residues 18-50_281-304
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF07158.18 best MatC_N 25.3 2.00e-05 98.2% 32.9%
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ot4A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.70 57.0 4.80e-01 96.5% 76.6%
3if8B02 1.20.58.730 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 55.0 4.68e-01 98.2% 57.0%
3hruB01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.64 46.0 3.59e-01 93.0% 35.2%
2wyhB04 1.20.1270.50 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain 0.63 52.0 4.42e-01 96.5% 81.2%
1qv9A02 6.10.140.120 Special › Helix non-globular › Helix Hairpins › 0.62 51.0 4.34e-01 96.5% 86.4%
4hwhE00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.61 53.0 4.56e-01 96.5% 89.8%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.59 50.0 4.26e-01 98.2% 90.8%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.58 51.0 4.51e-01 100.0% 89.4%
3t57A02 1.20.1180.10 Mainly Alpha › Up-down Bundle › Udp N-acetylglucosamine O-acyltransferase; Domain 2 › Udp N-acetylglucosamine O-acyltransferase, C-terminal domain 0.56 41.0 3.78e-01 78.9% 68.0%
5kbwB00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.55 43.0 3.08e-01 86.0% 35.7%
1ku9A02 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.53 37.0 3.56e-01 71.9% 100.0%
1l3pA00 1.20.120.320 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Group V grass pollen allergen 0.53 43.0 3.77e-01 100.0% 73.5%
3kavA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.53 42.0 3.68e-01 98.2% 72.5%
6z01B03 1.10.132.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.52 42.0 3.18e-01 94.7% 51.9%
4ielA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.52 43.0 3.49e-01 96.5% 70.7%
1vi0A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.51 39.0 3.05e-01 87.7% 77.2%
2vs0A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.51 38.0 3.37e-01 78.9% 90.2%
2hfiA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.50 42.0 3.37e-01 96.5% 61.0%
ECOD (14)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3590199 5060.2.1.1 alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › T2SSF 0.71 43.0 3.18e-01 77.2% 25.2%
4451107 304.8.1.53 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › GlnD_5th 0.61 49.0 3.54e-01 94.7% 30.0%
4178094 103.1.1.6 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › RuvA_C 0.60 48.0 4.93e-01 94.7% 92.7%
3838803 4168.1.1.0 alpha duplicates or obligate multimers › HAMP domain › HAMP domain › HAMP domain 0.59 51.0 4.91e-01 98.2% 87.7%
3846608 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.57 49.0 3.05e-01 96.5% 80.9%
3951251 305.1.1.7 a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › GDH_ACT2 0.56 44.0 3.27e-01 94.7% 30.6%
3984031 101.1.2.264 alpha arrays › HTH › HTH › winged helix domain › HTH_46 0.55 36.0 3.37e-01 80.7% 50.7%
4001581 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.54 41.0 2.98e-01 84.2% 29.1%
3898566 192.5.1.14 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1_TOCA 0.53 38.0 2.82e-01 75.4% 60.7%
3204414 1.1.17.0 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 0.53 39.0 2.44e-01 80.7% 87.7%
3652961 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.52 42.0 3.02e-01 96.5% 47.8%
3677077 7579.1.1.5 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Peptidase_S10 0.52 43.0 2.60e-01 100.0% 18.4%
3640877 101.1.2.627 alpha arrays › HTH › HTH › winged helix domain › Ovate 0.52 39.0 4.00e-01 80.7% 89.1%
4977823 1076.1.1.1 alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Rce1-like 0.50 41.0 2.72e-01 89.5% 57.4%
D3 medium residues 51-95_206-280
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF07158.18 best MatC_N 29.3 1.10e-06 39.2% 29.5%
CATH (17)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1nu7D02 1.20.120.760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Staphylcoagulase, helix bundle, domain 2 0.60 41.0 4.10e-01 100.0% 66.4%
4gzrB00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.60 33.0 3.95e-01 81.7% 81.8%
1lrzA03 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 32.0 4.13e-01 82.5% 98.4%
2uxwA04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.58 45.0 4.37e-01 97.5% 74.6%
7q37A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.56 49.0 4.03e-01 94.2% 75.7%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 32.0 3.93e-01 81.7% 94.4%
1egdA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.55 44.0 4.18e-01 98.3% 73.0%
2pg0A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.54 42.0 3.99e-01 98.3% 68.5%
1u8vB03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.53 46.0 3.83e-01 95.0% 66.7%
2o6yA02 1.20.200.10 Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) 0.53 46.0 3.45e-01 98.3% 85.6%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 34.0 3.37e-01 88.3% 62.5%
4irlB02 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.51 28.0 3.07e-01 99.2% 63.4%
3owaA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.51 46.0 4.13e-01 100.0% 90.1%
2pfmA02 1.20.200.10 Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) 0.51 42.0 3.42e-01 95.0% 88.7%
2rbdA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.50 38.0 3.54e-01 79.2% 86.7%
3caxA01 1.20.120.520 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like 0.50 43.0 3.57e-01 93.3% 61.3%
4akgA14 1.20.1280.160 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.50 33.0 3.45e-01 88.3% 72.5%
ECOD (20)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3988675 3355.1.1.29 alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS, MatC_N 0.97 94.0 6.11e-01 100.0% 53.3%
4983663 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.62 41.0 4.70e-01 95.0% 95.2%
3824153 611.7.1.11 alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › DUF7032 0.59 42.0 4.15e-01 96.7% 68.5%
5024439 633.6.1.1 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.57 43.0 4.11e-01 98.3% 66.9%
3943221 633.6.1.1 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.57 45.0 4.17e-01 98.3% 67.3%
3968650 633.6.1.0 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like 0.56 39.0 4.07e-01 95.0% 81.0%
5011014 633.6.1.1 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.55 47.0 4.41e-01 98.3% 76.6%
3588945 162.1.1.0 alpha bundles › PTS-regulatory domain, PRD › PTS-regulatory domain, PRD › PTS-regulatory domain, PRD 0.55 29.0 3.02e-01 92.5% 51.3%
4937687 601.1.1.155 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DUF456 0.54 38.0 4.10e-01 90.8% 87.9%
4946808 5081.1.1.1 alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid 0.54 34.0 2.96e-01 94.2% 37.9%
3960732 633.6.1.1 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.53 45.0 4.23e-01 98.3% 73.3%
4990287 4323.1.1.0 alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C 0.53 36.0 3.68e-01 73.3% 72.2%
4941191 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.53 40.0 4.23e-01 96.7% 88.2%
5030226 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.52 37.0 2.80e-01 72.5% 89.4%
5028028 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.52 43.0 4.13e-01 95.0% 79.3%
3802240 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.51 38.0 4.09e-01 97.5% 94.0%
4955333 3355.1.1.41 alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › DUF401 0.51 38.0 2.70e-01 78.3% 25.4%
3689935 633.6.1.1 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.51 41.0 3.52e-01 98.3% 54.2%
4947851 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.51 39.0 3.67e-01 97.5% 66.0%
3716257 1189.1.1.0 alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor 0.50 43.0 4.13e-01 91.7% 87.4%
D4 medium residues 96-205
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF07158.18 best MatC_N 31.2 3.10e-07 47.3% 34.9%
CATH (30)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.70 48.0 4.80e-01 93.6% 68.4%
3b4qA00 1.10.1200.100 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › conserved protein domain from corynebacterium diphtheriae 0.66 35.0 3.92e-01 77.3% 64.4%
1w9rA00 1.20.58.440 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › choline binding protein A 0.65 52.0 5.06e-01 88.2% 78.2%
1qv9A02 6.10.140.120 Special › Helix non-globular › Helix Hairpins › 0.64 46.0 4.77e-01 97.3% 80.6%
3qo8A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.63 46.0 4.67e-01 74.5% 93.4%
1qdbA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.63 43.0 3.96e-01 95.5% 53.8%
6r1nA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.63 46.0 4.75e-01 75.5% 96.1%
1i4dA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.63 51.0 4.35e-01 90.0% 88.8%
2gs4A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.63 47.0 4.14e-01 83.6% 54.4%
4iu9B02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.62 55.0 4.54e-01 98.2% 78.8%
2kbbA00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.61 52.0 4.42e-01 90.9% 90.8%
6lumD01 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.61 47.0 4.56e-01 82.7% 84.0%
2zcxA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.60 50.0 4.13e-01 92.7% 60.0%
2v0xA01 1.10.287.3160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.59 48.0 4.13e-01 85.5% 72.0%
6cnzF00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.59 49.0 4.34e-01 89.1% 96.2%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 41.0 4.11e-01 70.9% 70.9%
2optA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.59 50.0 4.61e-01 94.5% 87.5%
1e7pC00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.58 48.0 3.70e-01 90.9% 44.1%
2fp1B00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.58 50.0 4.41e-01 96.4% 95.7%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.57 43.0 4.27e-01 78.2% 92.0%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.57 49.0 4.98e-01 98.2% 96.3%
2f2cA02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.56 35.0 3.63e-01 85.5% 66.0%
4yjwA00 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.56 48.0 4.38e-01 99.1% 84.3%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.55 45.0 4.40e-01 95.5% 79.7%
4xt1A00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.55 46.0 3.50e-01 94.5% 78.7%
1siqA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.55 42.0 3.74e-01 93.6% 57.4%
3hugA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 37.0 4.18e-01 70.0% 97.5%
2l6hA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.54 47.0 4.28e-01 100.0% 81.8%
2okuA00 1.20.120.470 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Acyl-CoA dehydrogenase, C-terminal domain 0.52 45.0 4.43e-01 96.4% 91.8%
3lsjA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 43.0 3.89e-01 91.8% 83.0%
ECOD (31)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3988675 3355.1.1.29 alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS, MatC_N 0.95 93.0 5.88e-01 100.0% 25.7%
5072196 633.4.1.0 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor 0.69 44.0 4.57e-01 87.3% 70.0%
3273576 5001.1.1.31 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › GPR180-TMEM145_TM 0.66 56.0 4.27e-01 91.8% 63.5%
3715371 1076.1.1.1 alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Rce1-like 0.64 56.0 4.28e-01 98.2% 90.6%
3972755 601.1.2.99 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › DAGK_prokar 0.63 49.0 4.78e-01 85.5% 75.4%
5008568 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.63 44.0 3.57e-01 72.7% 67.9%
3573589 632.22.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA 0.62 47.0 4.90e-01 93.6% 86.0%
3931278 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.61 48.0 4.85e-01 97.3% 86.1%
4031685 5079.1.1.1 alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE 0.60 49.0 4.17e-01 90.0% 67.4%
3727064 5069.1.3.6 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › MCP1_TM 0.59 49.0 3.77e-01 90.9% 52.3%
4934608 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.59 51.0 4.75e-01 96.4% 87.9%
4025314 7064.1.1.1 alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 0.59 49.0 4.48e-01 94.5% 71.6%
4187499 1075.3.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 0.58 51.0 3.93e-01 99.1% 49.8%
4588403 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.58 45.0 4.14e-01 95.5% 62.7%
3960303 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.57 50.0 4.02e-01 94.5% 67.6%
3506288 4177.1.1.6 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3_WASP_bdg 0.57 50.0 4.02e-01 95.5% 81.3%
3784753 602.2.1.0 alpha arrays › L-aspartase middle domain-like › RNA-binding protein She2p › RNA-binding protein She2p 0.57 51.0 4.09e-01 98.2% 74.5%
3480514 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.56 44.0 4.01e-01 82.7% 93.1%
4994869 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 40.0 3.96e-01 88.2% 68.3%
5026394 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.56 45.0 4.50e-01 95.5% 83.5%
4960728 3236.1.1.1 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.56 45.0 3.04e-01 88.2% 70.6%
3725584 109.3.1.179 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › DUF7708 0.55 48.0 3.70e-01 97.3% 58.1%
4274219 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.54 46.0 4.45e-01 91.8% 83.3%
3177741 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.54 45.0 4.71e-01 93.6% 98.0%
4596937 605.1.1.247 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › PCRF 0.53 44.0 4.65e-01 93.6% 99.0%
4054880 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.53 44.0 4.58e-01 92.7% 94.3%
3789184 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.53 42.0 4.03e-01 89.1% 72.3%
3397539 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 47.0 3.63e-01 97.3% 74.6%
4022168 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.53 43.0 3.16e-01 88.2% 59.7%
4236152 1175.1.1.1 alpha complex topology › Apolipoprotein N-acyltransferase transmembrane domain › Apolipoprotein N-acyltransferase transmembrane domain › Apolipoprotein N-acyltransferase transmembrane domain › LNT_N 0.52 44.0 3.48e-01 92.7% 80.4%
None 0.52 46.0 3.08e-01 98.2% 85.1%