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CAKLQF020000015.1__CAH1087557.1__SAMEA5780031_02736__00057

Bact-Vir

CAKLQF020000015.1__CAH1087557.1__SAMEA5780031_02736__00057

Identity

Kingdom:
phage

Quality

88.1 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 414-527
PDB
Domain cluster: representative
CATH (25)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4hlbA00 3.30.70.2960 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.72 50.0 5.43e-01 76.3% 85.3%
1yj7D02 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.69 43.0 4.81e-01 73.7% 80.5%
6ijbA01 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.66 48.0 5.14e-01 99.1% 88.8%
3kxwA02 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.66 54.0 5.25e-01 100.0% 79.8%
2y27A02 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.66 50.0 5.25e-01 95.6% 88.3%
5uptA02 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.65 48.0 4.98e-01 99.1% 82.2%
3bioA02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.65 44.0 4.45e-01 93.9% 68.4%
7r7eA01 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.65 53.0 5.23e-01 100.0% 83.2%
6h1bA02 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.65 48.0 5.02e-01 100.0% 86.3%
2e8eA00 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.65 45.0 4.31e-01 71.1% 67.4%
1p7lA03 3.30.300.10 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › 0.64 44.0 4.53e-01 70.2% 85.8%
4gs5A02 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.63 48.0 4.97e-01 100.0% 86.7%
6he0A01 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.63 48.0 4.94e-01 95.6% 85.0%
2dyjA00 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.63 44.0 4.79e-01 97.4% 90.1%
3bypA00 3.30.70.1350 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cation efflux protein, cytoplasmic domain 0.61 40.0 4.54e-01 70.2% 91.5%
2ql8A00 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.61 45.0 4.23e-01 100.0% 62.9%
3laxA00 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.61 50.0 5.23e-01 94.7% 95.3%
4l4qA02 3.30.300.340 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › S-adenosylmethionine synthetase, N-terminal domain 0.59 47.0 4.57e-01 86.0% 84.3%
3w5xA00 3.30.70.1350 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cation efflux protein, cytoplasmic domain 0.59 39.0 4.51e-01 70.2% 96.2%
3k85A00 3.30.230.120 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.57 40.0 2.99e-01 72.8% 75.5%
2kdnA00 3.30.300.90 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › BolA-like 0.57 39.0 4.00e-01 76.3% 74.1%
4jj9C00 3.30.429.10 Alpha Beta › 2-Layer Sandwich › Macrophage Migration Inhibitory Factor › Macrophage Migration Inhibitory Factor 0.56 46.0 4.25e-01 88.6% 80.0%
1vw5A00 3.30.70.1420 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Structure from the mobile metagenome of cole harbour salt marsh: integron cassette protein hfx_cass1 0.55 47.0 4.31e-01 98.2% 70.2%
6iw6A02 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.53 42.0 4.34e-01 100.0% 89.8%
3n4pC00 3.30.420.320 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › DNA-packaging terminase, C-terminal nuclease domain 0.50 43.0 3.57e-01 96.5% 83.0%
ECOD (59)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4947673 327.5.1.0 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins 0.75 59.0 6.15e-01 97.4% 89.5%
5009414 327.5.1.3 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C_2 0.74 51.0 5.60e-01 93.0% 88.9%
4976057 327.5.1.0 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins 0.74 56.0 5.90e-01 88.6% 90.0%
5046008 327.5.1.4 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › GH3_C 0.74 66.0 6.34e-01 100.0% 85.4%
3464331 327.5.1.4 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › GH3_C 0.73 64.0 6.02e-01 94.7% 92.6%
3454551 327.5.1.4 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › GH3_C 0.73 67.0 5.95e-01 100.0% 85.0%
4947690 327.5.1.4 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › GH3_C 0.73 67.0 6.26e-01 100.0% 85.7%
5078419 327.5.1.4 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › GH3_C 0.72 66.0 6.12e-01 100.0% 89.0%
4960310 7584.1.1.1 a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › AMP-binding 0.72 60.0 3.98e-01 94.7% 22.9%
3525526 327.5.1.4 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › GH3_C 0.72 66.0 6.05e-01 100.0% 86.2%
4947725 327.5.1.0 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins 0.72 59.0 5.92e-01 97.4% 87.0%
4233591 327.4.1.1 a+b two layers › Alpha-lytic protease prodomain-like › YhbC-like, N-terminal domain › YhbC-like, N-terminal domain › RimP_N 0.72 49.0 5.59e-01 70.2% 94.1%
4979235 327.5.1.0 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins 0.71 65.0 6.19e-01 100.0% 88.1%
3824716 327.5.1.4 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › GH3_C 0.71 64.0 5.80e-01 100.0% 82.6%
3668191 323.1.1.0 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.71 65.0 4.11e-01 100.0% 22.3%
4120617 327.4.1.1 a+b two layers › Alpha-lytic protease prodomain-like › YhbC-like, N-terminal domain › YhbC-like, N-terminal domain › RimP_N 0.71 49.0 4.95e-01 75.4% 70.4%
3673430 327.5.1.4 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › GH3_C 0.71 64.0 5.73e-01 100.0% 76.9%
4082604 327.4.1.1 a+b two layers › Alpha-lytic protease prodomain-like › YhbC-like, N-terminal domain › YhbC-like, N-terminal domain › RimP_N 0.71 48.0 5.39e-01 70.2% 91.8%
3383561 327.5.1.4 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › GH3_C 0.70 63.0 5.57e-01 100.0% 78.8%
862039 327.5.1.4 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › GH3_C 0.68 61.0 5.67e-01 100.0% 82.1%
4218496 327.5.1.0 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins 0.68 58.0 5.96e-01 94.7% 96.4%
3861384 327.2.1.1 a+b two layers › Alpha-lytic protease prodomain-like › BolA-like › BolA-like › BolA 0.66 41.0 4.77e-01 70.2% 88.7%
5014112 327.7.1.0 a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like 0.66 45.0 4.87e-01 70.2% 85.3%
4579088 327.4.1.1 a+b two layers › Alpha-lytic protease prodomain-like › YhbC-like, N-terminal domain › YhbC-like, N-terminal domain › RimP_N 0.66 47.0 5.16e-01 73.7% 93.3%
3285521 327.5.1.6 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-dom_DIP2-like 0.65 53.0 5.21e-01 100.0% 83.3%
4208404 327.10.1.2 a+b two layers › Alpha-lytic protease prodomain-like › Ribosome-binding factor A (RbfA)-related › Ribosome-binding factor A (RbfA)-related › RBFA 0.64 46.0 4.52e-01 73.7% 77.5%
5039752 327.7.1.1 a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer 0.64 44.0 4.92e-01 86.8% 91.1%
4163850 327.4.1.1 a+b two layers › Alpha-lytic protease prodomain-like › YhbC-like, N-terminal domain › YhbC-like, N-terminal domain › RimP_N 0.63 45.0 5.11e-01 73.7% 97.6%
3970968 327.5.1.2 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C 0.63 49.0 5.02e-01 100.0% 86.4%
3917573 327.5.1.2 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C 0.63 48.0 4.89e-01 100.0% 82.7%
3947813 316.1.1.46 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › SseB_C 0.63 48.0 5.06e-01 91.2% 92.0%
5012775 327.7.1.0 a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like 0.63 43.0 4.78e-01 70.2% 90.9%
4447981 327.17.1.2 a+b two layers › Alpha-lytic protease prodomain-like › S-adenosylmethionine synthetase › S-adenosylmethionine synthetase › AdoMet_Synthase 0.63 47.0 4.73e-01 78.9% 91.3%
3970458 327.2.1.1 a+b two layers › Alpha-lytic protease prodomain-like › BolA-like › BolA-like › BolA 0.62 39.0 4.64e-01 73.7% 96.0%
5022655 327.11.1.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Prokaryotic type KH domain (KH-domain type II) 0.62 45.0 4.39e-01 76.3% 96.1%
4975327 327.7.1.1 a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer 0.62 42.0 4.83e-01 70.2% 96.5%
5081028 327.7.1.1 a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer 0.62 40.0 4.38e-01 72.8% 81.1%
5051422 327.7.1.0 a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like 0.62 42.0 4.69e-01 86.8% 88.9%
5081027 327.7.1.1 a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer 0.62 40.0 4.69e-01 70.2% 93.8%
4626207 327.2.1.1 a+b two layers › Alpha-lytic protease prodomain-like › BolA-like › BolA-like › BolA 0.61 39.0 4.52e-01 100.0% 91.3%
3202023 327.5.1.0 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins 0.61 49.0 4.65e-01 100.0% 73.3%
3387384 327.7.1.1 a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer 0.61 43.0 4.75e-01 79.8% 94.4%
3987655 327.7.1.1 a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer 0.61 40.0 4.49e-01 71.1% 85.6%
3577257 327.2.1.1 a+b two layers › Alpha-lytic protease prodomain-like › BolA-like › BolA-like › BolA 0.61 41.0 4.32e-01 73.7% 78.0%
4033371 327.7.1.1 a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer 0.60 43.0 4.68e-01 100.0% 90.5%
4949378 327.7.1.1 a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer 0.60 40.0 4.34e-01 72.8% 82.1%
3171583 327.7.1.0 a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like 0.60 44.0 4.53e-01 76.3% 85.7%
5037185 327.7.1.1 a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer 0.59 40.0 4.49e-01 100.0% 91.8%
3925211 327.11.1.4 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Prokaryotic type KH domain (KH-domain type II) › MRP-S24 0.59 42.0 4.00e-01 85.1% 60.7%
4032064 327.7.1.0 a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like 0.59 40.0 4.35e-01 70.2% 85.3%
3176440 327.7.1.0 a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like 0.58 43.0 4.50e-01 100.0% 85.7%
4986386 316.1.1.2 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 0.56 48.0 4.53e-01 97.4% 95.2%
3730197 327.7.1.1 a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer 0.56 38.0 4.26e-01 70.2% 91.1%
3838474 2008.1.1.78 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RE_endonuc 0.55 38.0 3.32e-01 100.0% 46.3%
5029779 316.1.1.0 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase 0.54 45.0 4.50e-01 91.2% 85.8%
4028488 224.1.1.0 a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like 0.53 41.0 3.83e-01 82.5% 83.6%
5016879 316.1.1.27 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › Polbeta 0.53 44.0 4.34e-01 92.1% 86.7%
4988165 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.51 45.0 3.89e-01 96.5% 80.6%
5079507 316.1.1.2 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 0.50 44.0 4.16e-01 100.0% 85.7%
D2 medium residues 1-28_93-123
PDB
Domain cluster: representative
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4k7cA01 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.82 46.0 2.70e-01 100.0% 8.4%
7kfuC02 1.20.120.920 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain 0.72 44.0 2.87e-01 100.0% 15.9%
5dcaA11 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.61 40.0 3.24e-01 89.8% 38.1%
7pi0S01 1.10.3460.10 Mainly Alpha › Orthogonal Bundle › Chlorophyll a-b binding protein › Chlorophyll a/b binding protein domain 0.60 44.0 3.00e-01 86.4% 24.5%
1zkkB00 2.170.270.10 Mainly Beta › Beta Complex › Beta-clip-like › SET domain 0.58 41.0 2.93e-01 72.9% 99.4%
1p65A00 6.10.140.90 Special › Helix non-globular › Helix Hairpins › 0.57 33.0 3.36e-01 86.4% 59.6%
3cw9A01 3.40.50.980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.57 41.0 2.86e-01 74.6% 90.2%
2bddA00 3.90.470.20 Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › 4'-phosphopantetheinyl transferase domain 0.57 43.0 3.26e-01 96.6% 37.0%
2i4lA01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.56 48.0 2.97e-01 94.9% 91.8%
4p79A00 1.20.140.150 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.55 46.0 3.22e-01 100.0% 29.8%
5e1wA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 44.0 3.27e-01 94.9% 63.7%
6ketA01 3.20.20.30 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Luciferase-like domain 0.53 35.0 2.12e-01 88.1% 11.6%
2zdiC00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.53 49.0 3.57e-01 100.0% 50.7%
6juvB01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 35.0 3.25e-01 94.9% 56.0%
2nyxB01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 41.0 3.27e-01 96.6% 74.6%
3broD00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 40.0 3.23e-01 93.2% 75.4%
6qpqB00 1.10.10.580 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Structural maintenance of chromosome 1. Chain E 0.51 34.0 3.03e-01 98.3% 50.6%
2zdiB00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.51 47.0 3.79e-01 100.0% 57.5%
ECOD (38)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3423775 601.16.1.8 alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › DUF1218 0.76 48.0 3.45e-01 100.0% 25.2%
5010374 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.67 41.0 3.52e-01 100.0% 38.9%
3879800 601.3.1.8 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › IQUB 0.67 36.0 2.69e-01 98.3% 22.9%
4375528 3681.1.1.0 a+b complex topology › Helical hairpin insertion in E. coli DNA-directed RNA polymerase beta subunit › Helical hairpin insertion in E. coli DNA-directed RNA polymerase beta subunit › Helical hairpin insertion in E. coli DNA-directed RNA polymerase beta subunit 0.61 44.0 3.60e-01 100.0% 42.9%
3244833 3914.1.1.2 alpha bundles › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › Anoctamin,Anoct_dimer 0.59 51.0 2.88e-01 100.0% 51.0%
3785619 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.58 46.0 3.66e-01 100.0% 44.3%
4649222 101.1.2.15 alpha arrays › HTH › HTH › winged helix domain › MarR 0.57 47.0 3.67e-01 91.5% 70.8%
3933114 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.57 46.0 2.88e-01 89.8% 82.1%
4002132 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.57 50.0 3.13e-01 98.3% 92.6%
3970671 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.57 45.0 4.14e-01 100.0% 66.7%
3714022 304.24.1.3 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › EFG_III 0.56 27.0 2.71e-01 84.7% 35.0%
3592627 601.23.1.0 alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III 0.56 41.0 2.67e-01 98.3% 18.1%
4880604 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.56 40.0 3.04e-01 98.3% 32.4%
3941255 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.55 51.0 3.18e-01 100.0% 76.9%
3519143 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.55 47.0 3.01e-01 96.6% 77.7%
3451364 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.55 25.0 2.48e-01 89.8% 33.8%
3928370 5001.1.1.69 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srd 0.55 50.0 3.15e-01 100.0% 76.8%
3611700 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.55 45.0 2.87e-01 91.5% 88.0%
3933689 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.54 48.0 2.99e-01 96.6% 87.7%
3734132 3542.1.1.3 alpha arrays › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Peptidase_A22B 0.53 46.0 2.93e-01 100.0% 71.1%
3865234 7581.1.1.22 a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like › Thiolase_N, ketoacyl-synt 0.53 38.0 2.43e-01 100.0% 16.1%
4025072 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.53 50.0 3.88e-01 100.0% 56.5%
3939311 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.53 45.0 3.68e-01 100.0% 50.9%
5060418 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.52 49.0 3.78e-01 100.0% 52.5%
3771989 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.52 48.0 3.60e-01 100.0% 68.9%
5000789 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.52 49.0 3.91e-01 100.0% 62.9%
3229643 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.52 47.0 3.70e-01 100.0% 50.8%
4033043 616.1.1.41 alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › Terminase_4 0.52 44.0 3.82e-01 100.0% 61.1%
5076133 101.1.2.55 alpha arrays › HTH › HTH › winged helix domain › SMC_ScpB 0.52 35.0 3.15e-01 94.9% 52.5%
3538408 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.52 47.0 3.97e-01 100.0% 67.4%
3630462 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.51 48.0 3.53e-01 100.0% 56.4%
3783976 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.51 48.0 4.08e-01 100.0% 87.8%
3321176 5051.1.1.6 alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Aa_trans 0.51 47.0 2.74e-01 98.3% 30.2%
3931606 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.51 46.0 3.69e-01 100.0% 55.7%
4463557 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.51 47.0 3.94e-01 100.0% 68.4%
4410759 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.50 46.0 3.63e-01 100.0% 54.8%
3790375 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.50 46.0 3.53e-01 100.0% 48.0%
4971296 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.50 29.0 2.59e-01 89.8% 43.8%
D3 medium residues 29-60_74-92
PDB
Domain cluster: representative
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3r9bA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.59 41.0 2.45e-01 72.5% 43.2%
D4 medium residues 61-73_337-403
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF23571.2 best GH3_M 57.3 1.80e-15 88.8% 93.3%
CATH (20)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4rt0A00 2.40.10.220 Mainly Beta › Beta Barrel › Thrombin, subunit H › predicted glycosyltransferase like domains 0.63 47.0 4.28e-01 81.2% 75.2%
2fhqA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.61 46.0 3.98e-01 83.7% 90.4%
2hq9B00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.61 47.0 4.03e-01 86.3% 95.6%
2i02A00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.60 46.0 3.91e-01 83.7% 88.6%
3r5lA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.59 44.0 3.95e-01 80.0% 93.1%
2iabA01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.59 45.0 3.80e-01 83.7% 86.7%
2oaiA00 3.30.465.10 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 › 0.58 37.0 3.74e-01 87.5% 63.7%
4umwA02 2.70.150.10 Mainly Beta › Distorted Sandwich › Calcium-transporting ATPase, cytoplasmic transduction domain A › Calcium-transporting ATPase, cytoplasmic transduction domain A 0.58 39.0 3.81e-01 70.0% 100.0%
3ci0J02 2.10.70.20 Mainly Beta › Ribbon › Complement Module; domain 1 › gspk-gspi-gspj complex like domains 0.58 36.0 4.14e-01 82.5% 98.0%
2hc8A00 2.70.150.10 Mainly Beta › Distorted Sandwich › Calcium-transporting ATPase, cytoplasmic transduction domain A › Calcium-transporting ATPase, cytoplasmic transduction domain A 0.57 41.0 3.64e-01 75.0% 81.4%
7ui8A01 2.60.40.3930 Mainly Beta › Sandwich › Immunoglobulin-like › 0.56 39.0 3.67e-01 73.8% 91.2%
4zgnB00 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.56 40.0 3.70e-01 75.0% 80.6%
1wdiA02 2.40.10.240 Mainly Beta › Beta Barrel › Thrombin, subunit H › QueA-like 0.56 42.0 4.34e-01 81.2% 91.8%
2m89A00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.53 34.0 2.92e-01 96.2% 38.8%
4dixA01 2.60.40.2700 Mainly Beta › Sandwich › Immunoglobulin-like › 0.53 37.0 3.62e-01 82.5% 66.7%
4mjdA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.53 35.0 3.20e-01 83.7% 48.7%
2rsxA00 3.10.450.420 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.52 34.0 2.73e-01 81.2% 33.3%
1dc1A01 3.40.91.10 Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › 0.51 39.0 2.87e-01 83.7% 33.3%
4u13A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.50 36.0 3.31e-01 76.2% 66.1%
1vwxM01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.50 34.0 3.39e-01 70.0% 95.3%
ECOD (16)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3668191 323.1.1.0 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.94 91.0 5.25e-01 100.0% 65.3%
3454550 4011.1.1.3 beta barrels › beta-barrel domain in acetyl-CoA synthetase-like proteins › beta-barrel domain in acetyl-CoA synthetase-like proteins › beta-barrel domain in acetyl-CoA synthetase-like proteins › GH3_M 0.93 73.0 6.84e-01 81.2% 91.6%
3824595 4011.1.1.3 beta barrels › beta-barrel domain in acetyl-CoA synthetase-like proteins › beta-barrel domain in acetyl-CoA synthetase-like proteins › beta-barrel domain in acetyl-CoA synthetase-like proteins › GH3_M 0.93 74.0 6.93e-01 82.5% 70.5%
3323771 4011.1.1.0 beta barrels › beta-barrel domain in acetyl-CoA synthetase-like proteins › beta-barrel domain in acetyl-CoA synthetase-like proteins › beta-barrel domain in acetyl-CoA synthetase-like proteins 0.93 75.0 6.08e-01 83.7% 56.3%
3434421 327.5.1.11 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › GH3_M 0.91 74.0 6.17e-01 83.7% 54.4%
3835087 4011.1.1.3 beta barrels › beta-barrel domain in acetyl-CoA synthetase-like proteins › beta-barrel domain in acetyl-CoA synthetase-like proteins › beta-barrel domain in acetyl-CoA synthetase-like proteins › GH3_M 0.91 71.0 6.94e-01 80.0% 94.1%
3914047 4011.1.1.3 beta barrels › beta-barrel domain in acetyl-CoA synthetase-like proteins › beta-barrel domain in acetyl-CoA synthetase-like proteins › beta-barrel domain in acetyl-CoA synthetase-like proteins › GH3_M 0.90 73.0 7.57e-01 83.7% 92.0%
5075764 4011.1.1.0 beta barrels › beta-barrel domain in acetyl-CoA synthetase-like proteins › beta-barrel domain in acetyl-CoA synthetase-like proteins › beta-barrel domain in acetyl-CoA synthetase-like proteins 0.89 61.0 6.35e-01 83.7% 76.0%
5046007 4011.1.1.3 beta barrels › beta-barrel domain in acetyl-CoA synthetase-like proteins › beta-barrel domain in acetyl-CoA synthetase-like proteins › beta-barrel domain in acetyl-CoA synthetase-like proteins › GH3_M 0.84 66.0 7.01e-01 81.2% 92.9%
4947689 4011.1.1.9 beta barrels › beta-barrel domain in acetyl-CoA synthetase-like proteins › beta-barrel domain in acetyl-CoA synthetase-like proteins › beta-barrel domain in acetyl-CoA synthetase-like proteins › GH3_C 0.82 65.0 6.89e-01 82.5% 94.3%
3966494 1.1.5.25 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › PilZ 0.66 50.0 4.52e-01 82.5% 73.6%
5029770 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.61 30.0 2.75e-01 88.7% 34.3%
3590113 10.13.1.1 beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase 0.59 40.0 3.74e-01 71.2% 91.0%
5012403 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.54 39.0 3.18e-01 78.8% 76.4%
2642957 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.51 34.0 3.44e-01 70.0% 75.3%
3328489 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.50 35.0 3.77e-01 82.5% 82.9%
D5 medium residues 189-276
PDB
Domain cluster: representative
CATH (7)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4nt1A00 1.10.3520.10 Mainly Alpha › Orthogonal Bundle › Glycolipid transfer protein, GLTP › Glycolipid transfer protein 0.59 44.0 3.49e-01 80.7% 91.0%
1vw4L01 3.90.1030.10 Alpha Beta › Alpha-Beta Complex › 50s Ribosomal Protein L17; Chain: A, › Ribosomal protein L17 0.58 50.0 4.41e-01 97.7% 84.4%
3r2qA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.52 34.0 3.19e-01 79.5% 53.1%
2iu1A00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.51 44.0 3.57e-01 98.9% 64.6%
3ay8A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.51 39.0 3.39e-01 83.0% 82.4%
3d8bB02 1.10.8.60 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.51 27.0 2.82e-01 76.1% 54.9%
2capA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.50 43.0 3.33e-01 100.0% 95.0%
ECOD (3)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3255561 601.7.1.4 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › Ribonuc_2-5A 0.60 43.0 3.72e-01 87.5% 49.6%
3479516 109.4.1.263 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › UVSSA_N 0.51 44.0 3.33e-01 96.6% 79.1%
3248107 176.1.1.0 alpha arrays › Annexin › Annexin › Annexin 0.51 38.0 4.16e-01 92.0% 100.0%