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CAKLQF020000017.1__CAH1088286.1__SAMEA5780031_02879__00011

Bact-Vir

CAKLQF020000017.1__CAH1088286.1__SAMEA5780031_02879__00011

Identity

Kingdom:
phage

Quality

79.1 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 8-118
PDB
Domain cluster: representative
CATH (32)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1y6xA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.83 41.0 4.61e-01 92.8% 62.1%
1yvwA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.81 42.0 4.62e-01 91.9% 62.0%
2oo2A00 1.20.1270.90 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like 0.76 46.0 5.50e-01 85.6% 88.2%
2yxhA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.76 43.0 4.29e-01 95.5% 54.9%
2pmrA00 1.20.1270.90 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like 0.76 48.0 5.71e-01 83.8% 93.4%
3t46A00 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.73 46.0 5.60e-01 85.6% 94.7%
1dkxA02 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.69 44.0 5.17e-01 78.4% 90.0%
4gywA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.66 41.0 4.25e-01 91.9% 65.7%
3r2kA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.66 51.0 4.56e-01 81.1% 87.7%
6fdpA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.66 42.0 4.13e-01 92.8% 59.2%
2vyiA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.65 42.0 4.00e-01 92.8% 55.5%
2c41C01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.65 51.0 4.65e-01 83.8% 97.3%
1nzeA00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.64 58.0 5.88e-01 98.2% 97.3%
1xwmA00 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.64 49.0 3.94e-01 82.9% 42.0%
4bg5B00 1.10.3160.10 Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 0.64 58.0 4.78e-01 100.0% 72.9%
3gw4A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.64 45.0 3.69e-01 95.5% 41.7%
4bejB02 1.20.120.1240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain 0.64 55.0 4.38e-01 94.6% 73.1%
3ro3A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.62 44.0 3.87e-01 95.5% 50.3%
2a9uA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.61 41.0 3.95e-01 76.6% 61.1%
1cpqA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.61 55.0 5.23e-01 99.1% 93.8%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.60 39.0 4.66e-01 76.6% 98.6%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.59 38.0 4.18e-01 76.6% 78.5%
1fioA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 55.0 4.52e-01 100.0% 83.7%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.59 44.0 4.61e-01 99.1% 87.0%
1q0gA00 1.20.120.400 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase 0.59 53.0 5.27e-01 100.0% 97.4%
4p9fA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.57 46.0 4.24e-01 85.6% 84.0%
4jhrB00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.57 43.0 3.15e-01 93.7% 30.1%
6wfqC01 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.54 40.0 3.73e-01 78.4% 76.8%
3vkgA02 1.20.140.100 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain 0.53 44.0 4.09e-01 92.8% 83.0%
3unoE00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.53 46.0 4.07e-01 98.2% 91.6%
3tm8B00 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.52 46.0 3.40e-01 100.0% 71.0%
3nymA00 6.10.290.10 Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.52 46.0 4.45e-01 96.4% 90.3%
ECOD (32)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1000511 159.1.1.1 alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › Hypothetical protein AF_0060 › MazG 0.76 43.0 4.28e-01 95.5% 54.4%
4949146 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.74 53.0 6.01e-01 85.6% 97.6%
4390679 632.7.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.74 45.0 5.44e-01 80.2% 90.7%
4564470 632.7.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 0.74 53.0 5.62e-01 83.8% 83.0%
3316910 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.72 63.0 5.58e-01 94.6% 69.0%
5028219 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.71 48.0 5.29e-01 85.6% 85.6%
3338353 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.70 61.0 5.36e-01 93.7% 68.1%
4942288 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.70 53.0 5.59e-01 85.6% 88.0%
4380113 632.15.1.4 alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) › HSP70 0.70 51.0 5.14e-01 83.8% 76.4%
3420292 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.69 61.0 5.51e-01 96.4% 75.3%
3776957 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.67 61.0 5.71e-01 100.0% 82.2%
3431118 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.67 49.0 5.01e-01 76.6% 83.6%
4325889 109.4.1.2253 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cohesin_load, TPR_8 0.67 48.0 3.56e-01 99.1% 30.7%
4938440 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.67 54.0 5.62e-01 85.6% 95.0%
4962581 5069.1.1.5 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cyt_bd_oxida_II 0.66 60.0 5.16e-01 100.0% 67.4%
4608785 5069.1.1.5 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cyt_bd_oxida_II 0.66 60.0 5.10e-01 100.0% 65.0%
5055533 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.65 50.0 4.61e-01 100.0% 63.6%
5030837 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.63 47.0 4.52e-01 77.5% 94.4%
3354926 9001.1.1.1 alpha bundles › TMEM120/ELO/TLC › TMEM120/ELO/TLC › TMEM120/ELO/TLC › TRAM_LAG1_CLN8 0.63 45.0 4.41e-01 74.8% 81.7%
5047710 109.4.1.192 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.61 49.0 4.02e-01 100.0% 47.0%
3977955 601.4.1.1 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TarH 0.61 55.0 5.03e-01 99.1% 84.1%
4031804 5069.1.1.15 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_C_asm 0.60 54.0 4.94e-01 99.1% 91.7%
4937924 632.18.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › hypothetical protein PA2901 › hypothetical protein PA2901 0.60 41.0 4.79e-01 85.6% 98.8%
4952530 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.59 54.0 5.04e-01 100.0% 84.4%
5069603 601.18.1.30 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › Cytochrom_C_asm 0.59 53.0 5.12e-01 100.0% 89.6%
3903076 632.11.1.9 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like › PIG-S 0.58 50.0 4.66e-01 91.9% 92.6%
3964503 5069.1.1.15 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_C_asm 0.57 49.0 4.55e-01 99.1% 90.5%
3263613 601.1.1.97 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DNA_repr_REX1B 0.56 48.0 4.38e-01 99.1% 71.6%
3829175 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.56 44.0 4.33e-01 82.9% 84.2%
3588868 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 42.0 4.18e-01 100.0% 74.2%
2543302 5054.1.1.58 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › YVC1_C 0.54 49.0 4.25e-01 100.0% 69.4%
3704369 3712.1.1.0 a+b complex topology › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 0.53 47.0 4.27e-01 96.4% 71.7%
D2 medium residues 219-319
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF10101.15 best DUF2339 52.8 4.40e-14 98.0% 14.4%
CATH (53)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3ug9A02 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.85 63.0 4.73e-01 77.2% 45.3%
1st6A04 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.81 58.0 5.56e-01 75.2% 72.6%
4od4A02 1.20.120.1780 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › UbiA prenyltransferase 0.80 60.0 5.67e-01 78.2% 79.0%
1nzeA00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.80 60.0 5.80e-01 78.2% 71.4%
2yevA03 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.78 60.0 4.84e-01 80.2% 52.7%
6t0bc02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.78 59.0 4.69e-01 79.2% 49.7%
2v6yA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.78 54.0 6.13e-01 78.2% 96.0%
2bvlA01 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 53.0 5.69e-01 76.2% 82.6%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.77 51.0 5.90e-01 74.3% 93.2%
1a7eA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.76 53.0 5.09e-01 78.2% 62.7%
1q0gA00 1.20.120.400 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase 0.75 55.0 5.24e-01 76.2% 78.6%
4dmvA01 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 51.0 5.47e-01 78.2% 82.4%
2p61A00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.75 55.0 5.33e-01 79.2% 68.4%
3iqcA00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.75 55.0 5.23e-01 77.2% 66.4%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.74 55.0 5.38e-01 77.2% 92.5%
1h6gA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.73 53.0 5.05e-01 76.2% 69.7%
2jx0A00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.71 52.0 4.82e-01 79.2% 59.5%
2odmA00 1.10.287.750 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like 0.69 50.0 5.44e-01 76.2% 100.0%
4ecgA00 1.20.1420.20 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › M75 peptidase, HXXE motif 0.68 62.0 4.18e-01 100.0% 87.8%
4adzA00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.68 47.0 5.01e-01 71.3% 100.0%
3eabE00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.68 51.0 5.46e-01 79.2% 97.7%
2wzkA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.68 56.0 5.50e-01 91.1% 92.7%
4in3B00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.68 58.0 3.58e-01 98.0% 16.1%
2qqyA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.67 50.0 4.56e-01 79.2% 95.7%
1t72A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.67 50.0 4.79e-01 78.2% 81.2%
3e6sA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.67 49.0 4.30e-01 78.2% 86.2%
1sumB02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.67 53.0 5.08e-01 85.1% 88.1%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.67 50.0 5.06e-01 78.2% 93.9%
5jrcA00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 59.0 4.86e-01 99.0% 78.5%
2hujA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.66 49.0 4.58e-01 78.2% 76.0%
1t98A02 1.20.58.590 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain 0.65 54.0 4.63e-01 91.1% 99.4%
3cf6E03 1.20.870.10 Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 0.65 56.0 5.19e-01 100.0% 73.3%
2lsgA00 1.20.58.1280 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DNA repair protein Rev1, C-terminal domain 0.65 52.0 5.27e-01 92.1% 88.7%
5m9dA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.64 54.0 4.89e-01 97.0% 66.7%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.64 45.0 4.54e-01 75.2% 72.0%
2xzeB00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.64 47.0 4.25e-01 79.2% 56.5%
3f0cA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.64 55.0 4.96e-01 97.0% 79.9%
3lsjA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.64 46.0 4.09e-01 77.2% 59.5%
1siqA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.63 48.0 4.16e-01 81.2% 71.0%
1kqfC00 1.20.950.20 Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C 0.63 51.0 3.94e-01 86.1% 63.9%
2fbnA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.62 50.0 4.39e-01 88.1% 57.5%
1xx7A00 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.62 52.0 4.39e-01 92.1% 86.6%
1jogA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.62 49.0 4.47e-01 85.1% 84.4%
1bk6A00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.61 51.0 3.36e-01 92.1% 21.8%
2oezA02 1.10.3900.10 Mainly Alpha › Orthogonal Bundle › YacF-like › YacF-like 0.59 49.0 4.11e-01 87.1% 67.5%
4iw9A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.59 47.0 4.62e-01 97.0% 78.8%
2n04A00 1.10.287.110 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain 0.59 40.0 3.96e-01 93.1% 66.7%
1ihgA02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.58 51.0 4.60e-01 100.0% 73.8%
3jrqA00 3.60.40.10 Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain 0.56 47.0 3.47e-01 92.1% 46.5%
2hjmA01 1.20.120.460 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › protein pf1176 like 0.54 42.0 4.55e-01 97.0% 98.8%
5kbwB00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.54 46.0 3.96e-01 98.0% 67.8%
3i2wA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.52 41.0 3.02e-01 83.2% 78.7%
3anwB00 1.20.58.2050 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.52 42.0 3.69e-01 90.1% 57.4%
ECOD (59)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3289734 109.4.1.637 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF2339 0.91 86.0 5.87e-01 100.0% 46.9%
3968993 109.4.1.637 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF2339 0.88 82.0 5.55e-01 100.0% 30.6%
5060592 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.87 76.0 6.63e-01 93.1% 68.3%
4968943 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.85 64.0 6.90e-01 77.2% 97.6%
3253937 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.84 62.0 5.86e-01 77.2% 72.5%
3727634 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.82 55.0 6.49e-01 85.1% 98.6%
3253933 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.81 61.0 5.65e-01 78.2% 70.4%
3290056 109.3.1.160 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › EccD 0.78 72.0 5.88e-01 100.0% 63.5%
3725615 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.78 53.0 5.94e-01 89.1% 88.7%
5040127 5039.1.1.1 alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › COX3 0.78 58.0 4.21e-01 78.2% 73.6%
4683110 5039.1.1.1 alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › COX3 0.78 59.0 4.62e-01 79.2% 49.0%
3585627 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.77 61.0 4.42e-01 93.1% 31.5%
3615307 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.77 57.0 5.87e-01 77.2% 83.2%
3689475 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.77 52.0 6.10e-01 86.1% 100.0%
4139505 601.13.1.2 alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS › FliS 0.77 56.0 5.12e-01 78.2% 59.2%
3783832 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.76 58.0 5.04e-01 78.2% 60.8%
4782662 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.75 66.0 5.05e-01 96.0% 47.8%
1758799 601.16.1.1 alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase 0.75 56.0 5.01e-01 78.2% 61.9%
2492494 601.33.1.1 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD 0.72 52.0 5.36e-01 83.2% 79.8%
3535566 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.72 54.0 5.02e-01 78.2% 75.2%
4214723 109.4.1.1248 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF2753 0.72 63.0 5.81e-01 96.0% 74.6%
4994869 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.72 63.0 5.97e-01 98.0% 80.8%
4935669 601.33.1.1 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD 0.71 51.0 4.59e-01 80.2% 53.6%
3620378 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.71 53.0 4.03e-01 78.2% 46.8%
5005597 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.71 51.0 4.62e-01 75.2% 79.3%
5007869 601.33.1.0 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain 0.70 55.0 5.60e-01 83.2% 85.0%
3619724 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.70 53.0 5.33e-01 79.2% 89.0%
3611927 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.69 55.0 5.41e-01 87.1% 92.7%
4283860 109.4.1.1253 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_Atp25_C 0.69 62.0 4.48e-01 99.0% 51.9%
4026286 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.69 51.0 4.68e-01 79.2% 97.8%
3905991 109.4.1.160 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF3384 0.69 54.0 4.18e-01 99.0% 37.4%
3549652 109.26.1.1 alpha superhelices › Repetitive alpha hairpins › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nucleoporin_C 0.67 58.0 3.45e-01 96.0% 12.6%
3924530 603.2.1.0 alpha bundles › STAT-like › STAT › STAT 0.67 59.0 4.09e-01 99.0% 79.7%
3656551 109.23.1.2 alpha superhelices › Repetitive alpha hairpins › C-terminal domain in vacuolar protein sorting-associated protein 54 › C-terminal domain in vacuolar protein sorting-associated protein 54 › ZW10_C2 0.67 58.0 4.84e-01 97.0% 58.3%
4966420 5060.1.1.1 alpha bundles › V-type ATP synthase subunit C › V-type ATP synthase subunit C › V-type ATP synthase subunit C › vATP-synt_AC39 0.66 54.0 4.40e-01 89.1% 76.9%
3632510 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.66 52.0 5.27e-01 90.1% 85.0%
4368996 109.4.1.2396 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vac14_Fab1_bd, ARM_ECM29 0.66 58.0 3.49e-01 99.0% 28.1%
3375125 601.19.1.0 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein 0.65 48.0 4.06e-01 76.2% 75.8%
5065168 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.65 48.0 4.01e-01 79.2% 78.4%
5020664 1075.5.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt 0.65 48.0 3.83e-01 78.2% 74.3%
3946572 5001.1.1.15 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TMR-DISM_7TM 0.65 50.0 3.90e-01 83.2% 40.4%
3902528 192.2.1.57 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › TBCA_PH 0.65 44.0 4.41e-01 70.3% 100.0%
3363015 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.64 49.0 4.32e-01 79.2% 70.0%
3767618 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.64 50.0 4.64e-01 87.1% 67.2%
3711833 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.64 51.0 4.33e-01 86.1% 52.7%
4030302 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.63 51.0 4.63e-01 87.1% 64.4%
3786622 109.4.1.682 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RasGEF_N 0.63 55.0 4.22e-01 98.0% 61.3%
4976398 622.1.1.0 alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain 0.63 56.0 5.57e-01 99.0% 99.0%
3661770 109.4.1.409 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Arm,IBB,Arm_3 0.63 52.0 3.29e-01 91.1% 17.6%
3760097 109.4.1.2917 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_12, TPR_14, TPR_16, TPR_19 0.62 57.0 4.41e-01 100.0% 54.0%
4644903 109.4.1.3269 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_10, TPR_16, TPR_19 0.62 56.0 4.30e-01 100.0% 50.4%
3505450 109.4.1.276 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › EDC4_C 0.61 53.0 4.84e-01 96.0% 88.9%
3544884 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.61 49.0 4.30e-01 87.1% 61.3%
3199952 5000.4.1.0 alpha arrays › Toxins' membrane translocation domains › delta-Endotoxin (insectocide), N-terminal domain › delta-Endotoxin (insectocide), N-terminal domain 0.59 49.0 3.98e-01 89.1% 73.7%
4527514 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 52.0 3.84e-01 100.0% 44.9%
4027216 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.57 48.0 4.74e-01 92.1% 96.2%
3220596 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.54 41.0 4.01e-01 82.2% 93.0%
3290433 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.54 40.0 4.17e-01 78.2% 87.8%
4027747 4982.1.1.0 alpha arrays › KaiA/RbsU domain-like › KaiA/RbsU domain › KaiA/RbsU domain 0.54 45.0 4.37e-01 100.0% 100.0%
D3 medium residues 492-621
PDB
Domain cluster: representative
CATH (57)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1fioA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 64.0 5.54e-01 86.2% 93.2%
2fbnA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.76 54.0 5.08e-01 100.0% 61.4%
2uubT00 1.20.58.110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 0.76 46.0 5.22e-01 72.3% 79.8%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.74 51.0 5.88e-01 71.5% 97.8%
2gs4A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.74 52.0 4.84e-01 71.5% 98.7%
2yevA03 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.73 52.0 4.59e-01 73.1% 62.0%
6t0bc02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.72 51.0 4.49e-01 73.1% 58.6%
4it4A02 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.71 47.0 5.43e-01 76.2% 94.5%
3c1yA02 1.20.1260.110 Mainly Alpha › Up-down Bundle › Ferritin › DNA integrity scanning linker region 0.71 56.0 5.41e-01 84.6% 73.6%
6adqG01 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.69 49.0 4.43e-01 73.1% 64.0%
2fupA00 1.20.58.300 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like 0.69 51.0 5.17e-01 76.2% 94.5%
1dlcA01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.69 62.0 5.17e-01 100.0% 70.3%
3u8vA00 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.68 38.0 4.70e-01 81.5% 86.7%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.68 48.0 4.89e-01 73.1% 79.7%
4agsB04 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.67 55.0 5.48e-01 100.0% 85.7%
4k0dA00 1.20.120.1730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.67 48.0 4.65e-01 73.8% 69.2%
2xs1A01 1.25.40.280 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › alix/aip1 like domains 0.66 59.0 4.28e-01 96.9% 78.7%
6ljaA01 1.50.10.100 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase 0.66 60.0 4.31e-01 98.5% 37.2%
1h6gA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.66 46.0 4.72e-01 71.5% 84.7%
4y6cA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.64 47.0 4.03e-01 100.0% 46.7%
2rkkA01 1.25.40.270 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 0.64 50.0 4.71e-01 81.5% 92.9%
3o2tA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.64 58.0 4.43e-01 100.0% 46.7%
2jx0A00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.64 47.0 4.69e-01 75.4% 74.8%
7fhyB01 1.50.10.100 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase 0.63 57.0 4.40e-01 100.0% 63.2%
4aifA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.63 46.0 4.53e-01 100.0% 70.1%
3bqoA00 1.25.40.210 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Telomere repeat-binding factor, dimerisation domain 0.62 43.0 3.74e-01 79.2% 46.0%
1orjD00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.61 42.0 4.34e-01 72.3% 72.8%
3lewA01 1.25.40.390 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.61 54.0 4.10e-01 100.0% 75.5%
1ya0A01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.59 55.0 4.64e-01 100.0% 62.6%
1zvzA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.59 41.0 4.21e-01 70.8% 80.6%
3zc0D00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 54.0 4.79e-01 100.0% 82.4%
4o6mA02 1.20.120.1760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain 0.59 51.0 4.46e-01 94.6% 83.1%
3zheC01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.58 53.0 4.69e-01 98.5% 90.2%
2hr2A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.58 50.0 4.71e-01 100.0% 76.3%
3dadA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.58 53.0 3.94e-01 100.0% 44.8%
6xpdA01 1.20.1510.10 Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain 0.58 46.0 4.04e-01 86.2% 68.8%
3qnkC00 1.25.40.390 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.57 51.0 3.46e-01 100.0% 34.2%
2epkX03 1.20.120.670 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › N-acetyl-b-d-glucoasminidase 0.57 51.0 4.27e-01 100.0% 67.4%
4od4A02 1.20.120.1780 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › UbiA prenyltransferase 0.56 46.0 4.78e-01 85.4% 98.3%
5b00A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.56 47.0 3.70e-01 97.7% 44.4%
3k66A01 1.20.120.770 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Amyloid precursor protein, E2 domain 0.56 48.0 4.12e-01 94.6% 96.7%
3syvA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.56 39.0 3.10e-01 71.5% 84.9%
8hk0B03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.55 43.0 4.25e-01 83.1% 91.3%
3lwjA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 45.0 3.99e-01 90.8% 76.7%
1r2jA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.54 42.0 4.14e-01 83.1% 88.2%
2xq9A02 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.54 42.0 4.40e-01 82.3% 97.5%
2d2sA02 1.20.58.1220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, C-terminal helical domain 0.53 39.0 4.32e-01 83.8% 100.0%
2hsbA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.53 42.0 4.26e-01 82.3% 98.4%
4epzA00 1.25.40.810 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › UpxZ 0.53 48.0 4.55e-01 100.0% 94.8%
2b1eA02 1.20.1310.30 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › 0.53 46.0 4.41e-01 97.7% 98.7%
3lsjA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.53 40.0 3.87e-01 81.5% 71.9%
7powA01 1.20.120.1760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain 0.52 47.0 4.07e-01 97.7% 72.2%
3nxcA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 44.0 4.05e-01 93.8% 80.8%
4fymF00 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.52 48.0 4.07e-01 100.0% 65.1%
3mnlB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 43.0 3.92e-01 91.5% 76.9%
3u66A00 1.25.40.590 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type IV / VI secretion system, DotU 0.52 46.0 4.22e-01 97.7% 75.6%
1h6gA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.51 41.0 4.25e-01 85.4% 99.2%
ECOD (59)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3560836 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.81 59.0 5.13e-01 80.8% 50.8%
3602790 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.79 66.0 5.61e-01 87.7% 82.0%
3756667 109.25.1.0 alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A 0.79 58.0 5.24e-01 81.5% 57.6%
3713307 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.78 61.0 5.73e-01 81.5% 99.4%
3325610 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.78 55.0 5.96e-01 83.8% 86.4%
3517330 603.2.1.1 alpha bundles › STAT-like › STAT › STAT › STAT_alpha 0.77 54.0 4.60e-01 72.3% 99.5%
4935725 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.73 54.0 5.35e-01 76.2% 75.6%
3684753 109.4.1.681 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans_2 0.71 65.0 4.49e-01 100.0% 32.2%
3294806 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.70 64.0 4.82e-01 100.0% 68.8%
3424090 109.4.1.362 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1,TPR_8 0.70 50.0 4.42e-01 100.0% 50.5%
3669088 109.4.1.1740 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF30991 0.69 63.0 4.89e-01 97.7% 69.6%
3810594 109.4.1.190 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_6 0.69 50.0 4.55e-01 100.0% 56.5%
3314513 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.69 46.0 4.29e-01 70.0% 54.0%
5047254 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.68 55.0 4.61e-01 100.0% 49.8%
3730238 3924.1.1.1 alpha complex topology › Sterol uptake control protein 2 › Sterol uptake control protein 2 › Sterol uptake control protein 2 › Fungal_trans_2 0.68 64.0 4.45e-01 100.0% 43.3%
3691598 109.4.1.681 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans_2 0.68 64.0 4.38e-01 100.0% 76.6%
3720782 109.4.1.681 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans_2 0.68 63.0 4.34e-01 99.2% 74.8%
3607638 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 56.0 4.15e-01 88.5% 43.4%
3967307 601.33.1.1 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD 0.67 46.0 4.69e-01 70.8% 76.9%
3728168 109.4.1.681 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans_2 0.67 63.0 4.46e-01 100.0% 89.3%
4355508 109.4.1.5 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1 0.67 53.0 4.76e-01 98.5% 60.0%
3715494 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.66 54.0 4.67e-01 100.0% 55.6%
3196427 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.66 60.0 4.23e-01 98.5% 75.3%
1030741 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.66 47.0 4.56e-01 73.8% 68.3%
3401856 601.34.1.1 alpha bundles › Four-helical up-and-down bundle › F-actin binding domain of Abl › F-actin binding domain of Abl › F_actin_bind 0.66 45.0 4.84e-01 77.7% 82.7%
3179847 109.4.1.681 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans_2 0.65 61.0 4.15e-01 100.0% 74.5%
4029809 109.4.1.292 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › eIF3a_PCI_TPR-like 0.65 57.0 3.94e-01 100.0% 29.0%
3609309 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.65 59.0 4.91e-01 100.0% 60.0%
4927814 109.10.1.1 alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.65 53.0 4.49e-01 86.2% 72.6%
5038395 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.65 46.0 4.40e-01 73.8% 62.6%
5057964 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.65 58.0 5.22e-01 96.2% 87.4%
4356223 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.64 46.0 4.59e-01 73.8% 83.0%
3938222 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 57.0 4.62e-01 98.5% 95.3%
3806204 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 55.0 4.75e-01 100.0% 59.5%
4997415 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.64 54.0 5.31e-01 94.6% 84.3%
3632206 109.4.1.465 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SPO22 0.63 56.0 4.32e-01 99.2% 42.3%
4008098 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.63 41.0 4.31e-01 70.8% 71.7%
3824447 109.4.1.843 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › EFR3_ARM 0.63 57.0 3.79e-01 98.5% 42.6%
3275304 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.62 42.0 4.29e-01 73.1% 70.4%
3715189 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.62 55.0 4.10e-01 95.4% 41.9%
3693285 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 55.0 4.49e-01 100.0% 78.0%
3693071 109.4.1.356 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.61 55.0 3.70e-01 100.0% 37.8%
3589078 191.1.1.63 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_N 0.61 50.0 4.50e-01 90.0% 75.8%
3253937 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.61 44.0 4.54e-01 74.6% 86.7%
3717421 109.4.1.198 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_12 0.61 53.0 3.81e-01 94.6% 51.4%
3617532 109.4.1.235 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SRP68 0.60 53.0 4.26e-01 96.9% 55.7%
3387211 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.59 53.0 4.42e-01 96.9% 72.4%
4409486 5069.1.1.15 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_C_asm 0.59 55.0 4.33e-01 100.0% 54.2%
3316583 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 52.0 5.07e-01 100.0% 85.5%
3341387 109.4.1.5 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1 0.59 53.0 4.93e-01 100.0% 78.1%
3740863 5069.1.1.4 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Ferric_reduct 0.59 49.0 4.19e-01 91.5% 69.8%
3306356 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 52.0 4.82e-01 100.0% 75.8%
3513656 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.58 54.0 4.67e-01 100.0% 91.3%
3741751 109.4.1.602 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Dor1 0.58 48.0 4.04e-01 91.5% 58.8%
3247352 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.58 44.0 4.47e-01 79.2% 83.2%
3180873 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.58 50.0 4.78e-01 95.4% 98.7%
3805810 109.4.1.1425 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exo84_C, PF27696 0.57 51.0 3.40e-01 100.0% 26.0%
3693382 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.57 50.0 4.69e-01 95.4% 95.6%
3174456 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.56 43.0 3.30e-01 82.3% 75.0%
D4 medium residues 622-675
PDB
Domain cluster: representative
D5 medium residues 676-804
PDB
Domain cluster: representative
CATH (24)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2z0qA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.66 54.0 4.72e-01 87.6% 73.1%
3purA03 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 48.0 5.13e-01 74.4% 100.0%
4dlqA02 1.25.40.610 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.66 47.0 5.29e-01 82.2% 100.0%
2dfkC01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.63 54.0 4.53e-01 90.7% 80.7%
4it4A02 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.63 41.0 4.76e-01 70.5% 93.4%
2e9fB01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.62 32.0 3.62e-01 89.1% 63.5%
7p3rA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.62 43.0 3.21e-01 70.5% 88.0%
5cwkA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.61 47.0 4.32e-01 100.0% 61.9%
4gouA03 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.60 46.0 4.02e-01 80.6% 76.6%
3nxcA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.59 49.0 4.44e-01 89.1% 85.9%
4dvyP01 1.10.357.130 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.58 43.0 3.80e-01 77.5% 88.8%
3mpxA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.57 51.0 4.38e-01 97.7% 87.4%
1cnt200 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.57 36.0 3.65e-01 79.1% 62.3%
1vdyA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.57 50.0 4.94e-01 98.4% 92.9%
3u3iA02 1.20.58.1110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 42.0 4.55e-01 92.2% 96.3%
1oe8A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.55 45.0 4.61e-01 92.2% 91.1%
2oexA02 1.20.140.50 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › alix/aip1 like domains 0.55 32.0 2.77e-01 86.0% 36.5%
6dewA01 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 44.0 3.93e-01 88.4% 82.1%
3cqcA00 1.20.190.50 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 0.54 48.0 3.94e-01 100.0% 67.2%
3lsjA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.53 40.0 3.79e-01 79.1% 73.9%
3o60A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 43.0 3.85e-01 89.1% 76.9%
3keyA01 1.10.10.1080 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Stn1, N-terminal wHTH domain 0.51 34.0 3.95e-01 93.0% 97.7%
1cpcB00 1.10.490.20 Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins 0.51 38.0 3.54e-01 79.1% 59.9%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 37.0 4.11e-01 89.9% 95.1%
ECOD (19)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5035107 3922.1.1.358 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › PF26119 0.64 35.0 3.75e-01 86.0% 60.5%
3465154 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 45.0 3.33e-01 95.3% 27.2%
3395986 109.4.1.480 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TMEM214 0.60 54.0 4.22e-01 96.9% 46.3%
3631315 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 46.0 4.40e-01 93.8% 68.4%
3685185 192.17.1.10 alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like › eIF-3c_N 0.59 47.0 4.85e-01 94.6% 90.8%
3633871 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.59 51.0 4.41e-01 96.1% 90.0%
3248733 109.4.1.335 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SEN1_N 0.59 52.0 3.36e-01 100.0% 32.6%
3731168 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.59 41.0 4.46e-01 71.3% 87.6%
3511166 206.1.1.44 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › DUF1679 0.59 50.0 3.63e-01 94.6% 60.3%
3586818 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 46.0 3.14e-01 91.5% 24.6%
3528480 150.1.1.56 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › DGKD_4H 0.54 40.0 4.21e-01 79.1% 89.2%
3809829 109.4.1.480 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TMEM214 0.53 47.0 3.27e-01 100.0% 46.9%
3251662 604.39.1.12 alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › VTT_dom 0.53 44.0 3.85e-01 90.7% 76.4%
4201685 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.53 40.0 4.14e-01 79.1% 85.8%
2572867 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.53 35.0 3.78e-01 86.8% 78.4%
3718234 109.4.1.449 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2,TPR_8 0.53 35.0 2.50e-01 100.0% 19.3%
3623581 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.53 45.0 3.80e-01 93.8% 86.4%
5001408 4995.1.1.0 alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like 0.51 37.0 4.10e-01 79.8% 97.0%
3518143 109.4.1.209 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Katanin_con80 0.50 46.0 3.92e-01 100.0% 70.7%
D6 medium residues 805-921
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF10101.15 best DUF2339 89.3 4.10e-25 100.0% 16.2%
CATH (40)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2x0cA01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.79 55.0 4.70e-01 70.9% 58.4%
2rpaA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.76 48.0 5.81e-01 89.7% 97.4%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.76 53.0 5.33e-01 70.9% 71.6%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.75 52.0 5.13e-01 70.1% 70.5%
1vctA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.75 52.0 5.43e-01 71.8% 83.5%
1konA01 1.10.10.200 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Integrase, N-terminal zinc-binding domain 0.73 38.0 4.92e-01 73.5% 88.2%
2v6yA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.72 45.0 5.50e-01 70.9% 98.7%
2kbbA00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.71 49.0 4.31e-01 70.9% 51.7%
1wcrA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.71 50.0 5.26e-01 70.9% 95.1%
2xl4A00 1.20.120.1420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › LntA helical domain 0.70 49.0 4.51e-01 70.9% 67.3%
2gs4A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.69 50.0 4.52e-01 74.4% 90.5%
3o7pA01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.69 49.0 3.91e-01 71.8% 57.8%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.68 41.0 4.57e-01 84.6% 75.3%
4etrB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.68 47.0 4.68e-01 70.9% 97.5%
1sziA02 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.67 46.0 4.42e-01 70.9% 68.6%
2qupA00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.66 46.0 4.62e-01 70.9% 72.3%
1bgfA00 1.10.532.10 Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain 0.66 46.0 4.53e-01 73.5% 67.7%
1kt1A03 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.66 46.0 4.17e-01 87.2% 53.2%
4xpwA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.65 48.0 4.63e-01 76.9% 68.7%
3agtA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.65 47.0 4.50e-01 75.2% 65.4%
3zc0D00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 55.0 4.67e-01 91.5% 76.5%
2c41C01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.64 47.0 4.35e-01 76.1% 93.3%
2oerA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.64 48.0 4.24e-01 81.2% 68.2%
1tqgA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.64 44.0 4.60e-01 70.1% 83.8%
5jrcA00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 54.0 4.60e-01 91.5% 76.3%
4u72A01 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 51.0 4.18e-01 87.2% 97.3%
2v5cA03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.63 49.0 4.76e-01 88.0% 73.1%
2wzkA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.63 46.0 4.74e-01 75.2% 94.5%
4i17A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.63 47.0 3.79e-01 78.6% 46.4%
3f4mA00 1.20.1440.160 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like 0.62 44.0 4.09e-01 76.9% 56.5%
1zb1A00 1.25.40.280 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › alix/aip1 like domains 0.61 50.0 3.53e-01 88.0% 43.1%
3fhnA03 1.10.357.100 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Dsl1p vesicle tethering complex, Tip20p subunit, domain C 0.60 54.0 4.73e-01 100.0% 71.8%
3bqoA00 1.25.40.210 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Telomere repeat-binding factor, dimerisation domain 0.60 44.0 3.72e-01 87.2% 45.0%
2yevA03 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.60 45.0 3.89e-01 79.5% 59.8%
1yw0A00 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 48.0 3.79e-01 88.9% 81.9%
6fdpA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.58 34.0 3.43e-01 83.8% 55.8%
4fxdA04 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.56 45.0 4.12e-01 86.3% 100.0%
1to9A00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.56 41.0 3.26e-01 82.9% 39.1%
3bniB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 42.0 3.68e-01 84.6% 67.8%
6i57A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.50 38.0 3.73e-01 80.3% 80.0%
ECOD (51)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4998672 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.79 54.0 6.14e-01 70.9% 90.0%
3675860 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.77 54.0 4.56e-01 70.9% 55.7%
4885878 601.1.1.2 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › CHASE3 0.76 54.0 4.91e-01 71.8% 58.0%
3317291 601.1.1.63 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Glyco_hydro81C 0.76 58.0 5.32e-01 99.1% 62.0%
3991191 601.1.2.6 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_IBS2B 0.76 53.0 4.86e-01 71.8% 60.0%
3511483 601.1.3.6 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 › Talin_IBS2B 0.76 52.0 4.75e-01 70.9% 58.1%
3938596 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.75 53.0 4.85e-01 71.8% 60.7%
5013248 601.3.1.1 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt 0.75 52.0 5.07e-01 70.1% 70.4%
3226477 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.74 52.0 4.00e-01 72.6% 41.6%
3186889 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.73 47.0 5.19e-01 74.4% 80.0%
3968139 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.73 50.0 4.09e-01 70.1% 49.5%
165995 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.72 45.0 5.50e-01 70.9% 98.7%
3255106 109.4.1.1137 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CNOT10_TPR 0.72 60.0 4.54e-01 94.9% 39.0%
3272556 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.71 45.0 3.79e-01 70.9% 38.5%
5072449 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.71 46.0 5.13e-01 70.9% 84.4%
3809724 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.71 52.0 4.89e-01 76.1% 72.9%
3847975 604.12.1.9 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › ATG1-like_MIT2 0.71 46.0 5.08e-01 80.3% 82.1%
3813462 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.71 53.0 5.03e-01 94.0% 67.4%
3971908 601.13.1.0 alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS 0.69 57.0 5.58e-01 94.0% 81.6%
3387281 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.69 48.0 3.96e-01 70.9% 57.1%
3741894 109.4.1.1890 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2, TPR_8, TPR_16, TPR_19 0.69 43.0 3.55e-01 84.6% 36.1%
3783474 604.12.1.71 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › TMD_POM152 0.68 47.0 4.75e-01 70.1% 84.3%
2157267 109.4.1.204 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_EZ 0.68 52.0 5.26e-01 94.0% 81.0%
4025945 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 54.0 5.24e-01 94.9% 76.9%
4003320 109.4.1.37 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BRO1 0.66 52.0 3.97e-01 88.0% 36.3%
4062828 5069.1.1.4 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Ferric_reduct 0.65 58.0 4.87e-01 99.1% 91.7%
4335888 129.1.1.5 alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › Ferric_reduct 0.65 58.0 4.90e-01 99.1% 94.4%
4947089 109.10.1.1 alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.65 55.0 4.61e-01 91.5% 73.8%
5036565 109.10.1.1 alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.65 55.0 4.69e-01 91.5% 77.8%
5023839 109.10.1.1 alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.64 54.0 4.53e-01 91.5% 72.0%
5065621 109.10.1.1 alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.64 54.0 4.41e-01 91.5% 67.0%
3868214 109.4.1.1302 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF30363 0.64 55.0 4.92e-01 92.3% 82.5%
4294164 129.1.1.5 alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › Ferric_reduct 0.63 57.0 4.75e-01 99.1% 72.2%
54353 4266.1.1.0 alpha bundles › Hyaluronidase domain-like › Hyaluronidase post-catalytic domain-like › Hyaluronidase post-catalytic domain-like 0.63 49.0 4.76e-01 88.0% 73.6%
3437714 6155.1.1.0 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter 0.63 56.0 5.46e-01 100.0% 87.7%
3904792 109.4.1.2788 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2, TPR_6, PF30363, PF30475 0.62 55.0 3.41e-01 96.6% 39.8%
2060764 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.61 55.0 5.35e-01 97.4% 89.1%
3407816 3832.1.1.1 alpha bundles › Tumor necrosis factor alpha-induced protein 8-like protein 2 › Tumor necrosis factor alpha-induced protein 8-like protein 2 › Tumor necrosis factor alpha-induced protein 8-like protein 2 › DUF758 0.61 44.0 3.96e-01 76.9% 53.4%
3325608 109.4.1.1851 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_ESP1 0.60 52.0 4.53e-01 98.3% 62.3%
4485824 129.1.1.5 alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › Ferric_reduct 0.60 53.0 4.40e-01 99.1% 90.0%
3245201 6155.1.1.1 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv 0.60 50.0 4.74e-01 99.1% 77.1%
4025193 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 50.0 3.96e-01 89.7% 62.8%
4979147 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.59 48.0 4.01e-01 88.9% 89.0%
3275032 6155.1.1.1 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv 0.59 50.0 4.87e-01 98.3% 84.6%
4369332 5039.1.1.1 alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › COX3 0.59 45.0 3.80e-01 78.6% 70.2%
3619000 601.1.3.6 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 › Talin_IBS2B 0.58 54.0 4.88e-01 100.0% 85.2%
5018763 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 49.0 4.24e-01 95.7% 71.1%
3784830 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 46.0 3.91e-01 92.3% 70.3%
5023247 5079.1.1.1 alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE 0.54 38.0 3.43e-01 74.4% 51.8%
4960168 3877.1.1.0 alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC 0.52 43.0 3.86e-01 88.9% 93.9%
4226755 2004.1.1.782 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23, AAA_29, SbcC_Walker_B 0.52 47.0 3.14e-01 100.0% 82.2%