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CAKLQF020000019.1__CAH1089700.1__SAMEA5780031_03065__00031
Bact-VirCAKLQF020000019.1__CAH1089700.1__SAMEA5780031_03065__00031
Identity
- Kingdom:
- phage
Quality
92.6
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 35-123
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01219.25 best | DAGK_prokar | 90.5 | 7.40e-26 | 98.9% | 85.3% |
CATH (82)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3g80A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.87 | 55.0 | 6.06e-01 | 76.4% | 78.1% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.84 | 59.0 | 5.56e-01 | 73.0% | 64.2% |
| 2fb5A01 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.82 | 60.0 | 6.60e-01 | 76.4% | 98.6% |
| 1st6A03 | 1.20.120.810 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle | 0.81 | 72.0 | 5.25e-01 | 100.0% | 37.6% |
| 2gtsA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.81 | 56.0 | 6.01e-01 | 76.4% | 83.1% |
| 3favD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.81 | 59.0 | 6.33e-01 | 76.4% | 87.2% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.80 | 69.0 | 6.32e-01 | 97.8% | 72.4% |
| 4nqiD00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.79 | 71.0 | 5.21e-01 | 100.0% | 75.0% |
| 1qkrB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.78 | 72.0 | 5.62e-01 | 100.0% | 52.2% |
| 3wfdB00 | 1.20.210.10 | Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain | 0.78 | 70.0 | 4.41e-01 | 100.0% | 22.0% |
| 2fcwA00 | 1.20.81.10 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain | 0.78 | 66.0 | 6.28e-01 | 94.4% | 96.2% |
| 4dylA02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.77 | 57.0 | 5.65e-01 | 77.5% | 83.0% |
| 6iknD01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.77 | 66.0 | 4.64e-01 | 92.1% | 82.0% |
| 2yf4F00 | 1.10.3420.10 | Mainly Alpha › Orthogonal Bundle › putative ntp pyrophosphohydrolase like fold › putative ntp pyrophosphohydrolase like domain | 0.76 | 57.0 | 4.82e-01 | 78.7% | 78.3% |
| 3tulB00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.76 | 68.0 | 5.88e-01 | 96.6% | 87.2% |
| 4abmD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.76 | 56.0 | 5.99e-01 | 77.5% | 93.5% |
| 3sjqC00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.76 | 49.0 | 5.17e-01 | 74.2% | 73.8% |
| 4mh6A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.76 | 56.0 | 4.56e-01 | 77.5% | 43.4% |
| 1zvzA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.75 | 68.0 | 6.11e-01 | 100.0% | 71.8% |
| 2e87A01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.75 | 67.0 | 5.54e-01 | 100.0% | 63.7% |
| 2kp8A00 | 1.20.5.170 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.75 | 49.0 | 5.42e-01 | 85.4% | 83.3% |
| 1ku9A02 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.74 | 52.0 | 5.86e-01 | 74.2% | 100.0% |
| 4k0dA00 | 1.20.120.1730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.74 | 63.0 | 5.37e-01 | 100.0% | 58.0% |
| 3ck6C02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.74 | 52.0 | 4.72e-01 | 73.0% | 57.1% |
| 2b5uA02 | 1.10.287.620 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins | 0.74 | 55.0 | 4.51e-01 | 78.7% | 50.9% |
| 1wa8A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.74 | 55.0 | 5.36e-01 | 78.7% | 71.7% |
| 2qe7G01 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.74 | 53.0 | 5.18e-01 | 75.3% | 69.1% |
| 2ix5A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.73 | 64.0 | 5.34e-01 | 96.6% | 58.1% |
| 4gczA03 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.73 | 49.0 | 5.58e-01 | 73.0% | 95.4% |
| 3okqA00 | 1.20.58.1540 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain | 0.73 | 53.0 | 4.73e-01 | 76.4% | 57.6% |
| 3ehfD01 | 1.20.5.1930 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.73 | 50.0 | 5.68e-01 | 73.0% | 100.0% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.73 | 54.0 | 5.53e-01 | 78.7% | 89.4% |
| 2ch7A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.73 | 53.0 | 3.61e-01 | 76.4% | 95.5% |
| 1s35A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 51.0 | 4.89e-01 | 76.4% | 64.4% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.72 | 64.0 | 5.86e-01 | 100.0% | 79.7% |
| 6r1nA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.72 | 60.0 | 5.75e-01 | 91.0% | 98.1% |
| 3lssA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.72 | 55.0 | 5.14e-01 | 82.0% | 86.6% |
| 3g67A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.72 | 52.0 | 3.98e-01 | 77.5% | 42.3% |
| 7p3rA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.72 | 65.0 | 4.37e-01 | 100.0% | 42.2% |
| 2yfaB01 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.72 | 59.0 | 5.41e-01 | 100.0% | 68.1% |
| 2c0uA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.72 | 64.0 | 5.19e-01 | 100.0% | 59.8% |
| 2rfqC03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.71 | 63.0 | 5.09e-01 | 100.0% | 55.4% |
| 2xokP00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.71 | 52.0 | 5.62e-01 | 78.7% | 94.6% |
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.71 | 63.0 | 4.97e-01 | 100.0% | 84.0% |
| 1qsdA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 51.0 | 4.93e-01 | 76.4% | 66.7% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.70 | 46.0 | 4.71e-01 | 71.9% | 69.4% |
| 4egwA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.70 | 51.0 | 4.64e-01 | 76.4% | 58.8% |
| 2bl2A00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.70 | 61.0 | 5.09e-01 | 97.8% | 60.3% |
| 6h9xA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.70 | 58.0 | 5.55e-01 | 91.0% | 98.0% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.70 | 53.0 | 4.96e-01 | 80.9% | 66.1% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.70 | 50.0 | 4.84e-01 | 76.4% | 67.6% |
| 6qumQ00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.69 | 51.0 | 5.48e-01 | 79.8% | 93.2% |
| 2wgmA01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.69 | 51.0 | 5.36e-01 | 78.7% | 87.8% |
| 3uo2B02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.69 | 46.0 | 4.78e-01 | 70.8% | 72.6% |
| 3khkB01 | 1.20.1260.30 | Mainly Alpha › Up-down Bundle › Ferritin › N6 adenine-specific DNA methyltransferase, N-terminal domain | 0.69 | 55.0 | 4.54e-01 | 85.4% | 81.8% |
| 6p73A02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.69 | 58.0 | 4.99e-01 | 100.0% | 58.0% |
| 3axjB01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.69 | 51.0 | 4.25e-01 | 78.7% | 45.2% |
| 4jioA01 | 1.20.120.560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain | 0.69 | 60.0 | 5.02e-01 | 100.0% | 78.9% |
| 1u7lA02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.68 | 56.0 | 4.44e-01 | 89.9% | 77.0% |
| 1auwA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.68 | 61.0 | 4.54e-01 | 100.0% | 79.8% |
| 4rm7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.68 | 60.0 | 5.22e-01 | 100.0% | 65.5% |
| 1z0pA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 46.0 | 5.06e-01 | 70.8% | 91.8% |
| 1lvfB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 50.0 | 4.73e-01 | 77.5% | 70.2% |
| 6ygiB01 | 1.10.4090.10 | Mainly Alpha › Orthogonal Bundle › Hepatitis B viral capsid (hbcag) fold › Viral capsid, core domain supefamily, Hepatitis B virus | 0.67 | 57.0 | 4.86e-01 | 95.5% | 66.4% |
| 3anwA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 46.0 | 4.26e-01 | 73.0% | 55.8% |
| 1w0bA01 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.67 | 46.0 | 4.60e-01 | 74.2% | 69.6% |
| 1qv9A02 | 6.10.140.120 | Special › Helix non-globular › Helix Hairpins › | 0.66 | 60.0 | 5.76e-01 | 100.0% | 98.1% |
| 6h2dS01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.66 | 58.0 | 4.41e-01 | 100.0% | 43.0% |
| 2ot4A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.66 | 54.0 | 5.18e-01 | 100.0% | 77.6% |
| 3nvoB02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.65 | 47.0 | 4.35e-01 | 76.4% | 61.2% |
| 1m6nA04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.65 | 56.0 | 4.91e-01 | 97.8% | 66.7% |
| 3vr4B04 | 1.10.1140.10 | Mainly Alpha › Orthogonal Bundle › Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain; Chain D, domain3 › Bovine Mitochondrial F1-atpase; Atp Synthase Beta Chain; Chain D, domain 3 | 0.65 | 46.0 | 3.96e-01 | 100.0% | 45.0% |
| 1nktA04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.64 | 55.0 | 4.47e-01 | 97.8% | 96.0% |
| 3v5uA01 | 6.10.280.80 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region | 0.64 | 46.0 | 4.99e-01 | 76.4% | 92.1% |
| 4ciuA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.63 | 54.0 | 4.34e-01 | 98.9% | 83.3% |
| 6t4hA03 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.63 | 55.0 | 4.48e-01 | 98.9% | 99.4% |
| 4o6yB00 | 1.20.120.1770 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.63 | 55.0 | 4.24e-01 | 100.0% | 81.0% |
| 7zo9A01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.62 | 55.0 | 3.82e-01 | 100.0% | 41.9% |
| 5yixA00 | 1.10.601.10 | Mainly Alpha › Orthogonal Bundle › RNA Polymerase Primary Sigma Factor › RNA Polymerase Primary Sigma Factor | 0.61 | 52.0 | 3.65e-01 | 100.0% | 84.9% |
| 2fp1B00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.57 | 51.0 | 4.16e-01 | 100.0% | 90.2% |
| 1zylA03 | 1.20.1270.170 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.56 | 49.0 | 4.70e-01 | 97.8% | 84.5% |
| 2gbbB00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.55 | 48.0 | 4.06e-01 | 98.9% | 91.0% |
ECOD (86)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1790834 | 3086.1.1.1 ↗ | alpha bundles › Diacylglycerol kinase (DAGK) › Diacylglycerol kinase (DAGK) › Diacylglycerol kinase (DAGK) › DAGK_prokar | 0.92 | 81.0 | 8.40e-01 | 93.3% | 97.6% |
| 4475459 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.85 | 79.0 | 6.69e-01 | 100.0% | 68.6% |
| 3770066 | 3291.1.1.169 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › KIF21A_4th | 0.83 | 62.0 | 4.69e-01 | 77.5% | 35.9% |
| 3775753 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.83 | 61.0 | 3.55e-01 | 77.5% | 9.9% |
| 3839497 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.82 | 57.0 | 5.82e-01 | 76.4% | 75.3% |
| 3270560 | 4177.1.1.4 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › IMD | 0.81 | 74.0 | 5.29e-01 | 100.0% | 71.0% |
| 3599773 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.80 | 59.0 | 4.55e-01 | 77.5% | 37.4% |
| 4562953 | 2004.1.1.43 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SRP54 | 0.80 | 60.0 | 4.10e-01 | 78.7% | 24.9% |
| 3700663 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.79 | 69.0 | 6.68e-01 | 98.9% | 85.0% |
| 5074351 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.78 | 73.0 | 6.65e-01 | 100.0% | 78.8% |
| 3489411 | 601.1.2.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin | 0.78 | 71.0 | 5.76e-01 | 100.0% | 60.0% |
| 3805445 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.78 | 71.0 | 5.62e-01 | 100.0% | 53.1% |
| 3510367 | 603.1.1.99 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 | 0.78 | 57.0 | 4.69e-01 | 76.4% | 43.9% |
| 3886622 | 192.29.1.57 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Ninjurin | 0.78 | 70.0 | 6.09e-01 | 100.0% | 71.9% |
| 3823040 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.78 | 70.0 | 5.65e-01 | 100.0% | 57.6% |
| 3655688 | 3755.3.1.303 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A_4th | 0.78 | 57.0 | 4.54e-01 | 77.5% | 88.6% |
| 3833042 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.78 | 70.0 | 5.63e-01 | 100.0% | 54.1% |
| 3546060 | 4177.1.1.10 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › GMIP-like_FCH | 0.77 | 68.0 | 4.75e-01 | 100.0% | 76.3% |
| 4405928 | 5086.1.1.196 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_YknX | 0.76 | 56.0 | 6.12e-01 | 76.4% | 97.1% |
| None | — | 0.76 | 54.0 | 4.09e-01 | 76.4% | 32.5% | |
| 3273065 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.76 | 56.0 | 3.61e-01 | 77.5% | 23.2% |
| 3838243 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.76 | 69.0 | 5.94e-01 | 100.0% | 85.2% |
| 3678718 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.75 | 68.0 | 6.44e-01 | 100.0% | 94.3% |
| 4297833 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.75 | 55.0 | 5.56e-01 | 77.5% | 77.8% |
| 4541080 | 3755.1.1.11 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › She9_MDM33 | 0.75 | 55.0 | 4.73e-01 | 77.5% | 57.9% |
| 3746433 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.75 | 67.0 | 4.71e-01 | 100.0% | 63.9% |
| 3565534 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.75 | 66.0 | 4.80e-01 | 97.8% | 81.2% |
| 3944950 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.74 | 50.0 | 5.64e-01 | 76.4% | 93.8% |
| 3210394 | 129.1.1.0 ↗ | alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.74 | 54.0 | 4.75e-01 | 76.4% | 52.3% |
| 3741801 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.74 | 55.0 | 4.87e-01 | 77.5% | 61.6% |
| 5018993 | 601.30.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N | 0.74 | 61.0 | 5.40e-01 | 100.0% | 63.2% |
| 4561291 | 632.22.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA | 0.74 | 65.0 | 6.24e-01 | 100.0% | 87.6% |
| 3183024 | 3755.3.1.46 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › She9_MDM33 | 0.73 | 54.0 | 4.63e-01 | 77.5% | 57.9% |
| 3181110 | 5086.1.1.110 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HisKA | 0.73 | 54.0 | 5.32e-01 | 78.7% | 98.9% |
| 4977416 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.73 | 53.0 | 3.90e-01 | 77.5% | 30.5% |
| 4479045 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.73 | 53.0 | 3.99e-01 | 77.5% | 35.5% |
| 3953329 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.73 | 65.0 | 5.07e-01 | 100.0% | 77.9% |
| 3318812 | 192.8.1.248 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › KIF21A_4th | 0.72 | 53.0 | 4.48e-01 | 77.5% | 51.3% |
| 4039014 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.72 | 59.0 | 5.51e-01 | 87.6% | 92.7% |
| 4259085 | 3755.4.1.66 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › MCPsignal | 0.72 | 52.0 | 3.60e-01 | 75.3% | 23.8% |
| 3935462 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.72 | 52.0 | 4.17e-01 | 75.3% | 42.9% |
| 3636681 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.72 | 64.0 | 4.41e-01 | 100.0% | 66.5% |
| 3337008 | 192.2.1.60 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › KIF21A_4th | 0.72 | 53.0 | 4.53e-01 | 77.5% | 55.0% |
| 3927738 | 632.8.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 | 0.71 | 60.0 | 5.91e-01 | 94.4% | 95.8% |
| 3666876 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.71 | 60.0 | 5.24e-01 | 89.9% | 66.9% |
| 3493358 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.71 | 52.0 | 5.24e-01 | 77.5% | 77.8% |
| 3423387 | 611.9.1.0 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain | 0.71 | 59.0 | 5.50e-01 | 98.9% | 73.6% |
| 3578418 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.71 | 51.0 | 4.49e-01 | 76.4% | 50.4% |
| 4023330 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.71 | 63.0 | 5.07e-01 | 100.0% | 57.1% |
| 3924662 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.70 | 49.0 | 4.80e-01 | 76.4% | 67.4% |
| 5057328 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.70 | 54.0 | 3.48e-01 | 83.1% | 39.1% |
| 4177204 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.70 | 51.0 | 3.84e-01 | 77.5% | 37.3% |
| 3595103 | 3860.1.1.0 ↗ | alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm | 0.70 | 50.0 | 4.42e-01 | 76.4% | 51.9% |
| 4214525 | 632.22.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA | 0.70 | 61.0 | 5.94e-01 | 100.0% | 92.0% |
| 3656660 | 5001.1.1.32 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Solute_trans_a | 0.70 | 62.0 | 4.45e-01 | 100.0% | 34.3% |
| 4549103 | 3755.4.1.54 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PF30340 | 0.70 | 51.0 | 3.34e-01 | 77.5% | 18.2% |
| 3536637 | 633.23.1.22 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL | 0.69 | 60.0 | 5.13e-01 | 100.0% | 59.4% |
| 3404906 | 4044.1.1.0 ↗ | alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins | 0.69 | 58.0 | 5.68e-01 | 100.0% | 84.0% |
| 3810801 | 632.22.1.139 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › KIF21A_4th | 0.69 | 51.0 | 4.30e-01 | 77.5% | 55.3% |
| 3958889 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.69 | 49.0 | 4.02e-01 | 75.3% | 39.4% |
| 3942983 | 101.1.4.8 ↗ | alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like › Phage_CP76 | 0.69 | 45.0 | 3.78e-01 | 71.9% | 39.3% |
| 3535762 | 3187.1.1.2 ↗ | alpha bundles › Microtubule-Binding Domain of Flagellar Dynein › Microtubule-Binding Domain of Flagellar Dynein › Microtubule-Binding Domain of Flagellar Dynein › DUF4795 | 0.69 | 60.0 | 4.75e-01 | 100.0% | 59.5% |
| 3222373 | 605.4.1.18 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › PF29357 | 0.69 | 55.0 | 5.66e-01 | 100.0% | 92.9% |
| 3500905 | 604.13.1.1 ↗ | alpha bundles › Spectrin repeat-like › USP8 N-terminal domain-like › USP8 N-terminal domain-like › USP8_dimer | 0.68 | 48.0 | 4.28e-01 | 73.0% | 87.2% |
| 3807188 | 3562.1.1.11 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › PGG | 0.68 | 60.0 | 5.09e-01 | 100.0% | 70.0% |
| 3516673 | 601.33.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › PPP1R21_helical | 0.68 | 60.0 | 4.95e-01 | 100.0% | 58.8% |
| 3250231 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.68 | 60.0 | 4.59e-01 | 100.0% | 69.8% |
| 3855328 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.68 | 59.0 | 5.80e-01 | 96.6% | 90.5% |
| 4129922 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.67 | 56.0 | 5.45e-01 | 91.0% | 93.0% |
| 3954540 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.67 | 49.0 | 4.61e-01 | 77.5% | 65.5% |
| 3852486 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.67 | 59.0 | 4.99e-01 | 100.0% | 58.7% |
| 3326073 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.66 | 47.0 | 4.41e-01 | 74.2% | 60.9% |
| 4501553 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.66 | 58.0 | 5.25e-01 | 100.0% | 95.2% |
| 3672770 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.66 | 56.0 | 5.57e-01 | 98.9% | 89.5% |
| 3471023 | 164.1.1.15 ↗ | alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › PPPI_inhib | 0.66 | 50.0 | 4.12e-01 | 80.9% | 45.6% |
| 3997336 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.66 | 58.0 | 5.23e-01 | 100.0% | 71.2% |
| 3971315 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.65 | 58.0 | 5.50e-01 | 98.9% | 100.0% |
| 4652719 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.65 | 47.0 | 4.62e-01 | 77.5% | 71.6% |
| 3780286 | 244.1.1.6 ↗ | a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C › Amino_oxidase | 0.65 | 47.0 | 2.93e-01 | 78.7% | 12.9% |
| 4051951 | 605.2.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 | 0.63 | 45.0 | 4.57e-01 | 76.4% | 78.9% |
| 3460324 | 3291.1.1.51 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PGG | 0.63 | 55.0 | 4.78e-01 | 100.0% | 64.3% |
| 4011174 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.62 | 45.0 | 4.33e-01 | 78.7% | 97.1% |
| 4949599 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.61 | 54.0 | 4.67e-01 | 100.0% | 65.5% |
| 4561607 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.61 | 53.0 | 4.84e-01 | 98.9% | 90.8% |
| 3258502 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.60 | 51.0 | 4.02e-01 | 100.0% | 79.0% |
| 4946656 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.55 | 47.0 | 4.27e-01 | 95.5% | 80.8% |