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CAKLQF020000022.1__CAH1091143.1__SAMEA5780031_03263__00022
Bact-VirCAKLQF020000022.1__CAH1091143.1__SAMEA5780031_03263__00022
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 2-98
Domain cluster:
representative
CATH (34)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3n5lA03 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.82 | 46.0 | 5.93e-01 | 77.3% | 94.7% |
| 4rm7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.75 | 55.0 | 4.83e-01 | 76.3% | 92.1% |
| 6gy8A01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.72 | 57.0 | 3.90e-01 | 84.5% | 74.4% |
| 1y1uA01 | 1.20.1050.20 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain | 0.68 | 50.0 | 3.96e-01 | 77.3% | 100.0% |
| 1vx7301 | 1.10.287.310 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.66 | 44.0 | 4.97e-01 | 75.3% | 87.8% |
| 2e9xA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 48.0 | 4.35e-01 | 75.3% | 64.8% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 44.0 | 4.29e-01 | 83.5% | 61.7% |
| 3ns4A00 | 1.10.357.110 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Vacuolar protein sorting-associated protein 53, C-terminus | 0.66 | 53.0 | 4.14e-01 | 86.6% | 78.0% |
| 2rp4A00 | 6.10.280.60 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain | 0.66 | 45.0 | 5.19e-01 | 82.5% | 97.2% |
| 1qgtB00 | 1.10.4090.10 | Mainly Alpha › Orthogonal Bundle › Hepatitis B viral capsid (hbcag) fold › Viral capsid, core domain supefamily, Hepatitis B virus | 0.65 | 49.0 | 4.26e-01 | 79.4% | 76.9% |
| 1hciA04 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 46.0 | 4.43e-01 | 75.3% | 78.9% |
| 1dtoA01 | 1.10.287.30 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 | 0.64 | 49.0 | 4.88e-01 | 80.4% | 85.3% |
| 3rq9A00 | 1.10.287.2500 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.64 | 39.0 | 4.31e-01 | 78.4% | 75.6% |
| 7sf8A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.64 | 46.0 | 3.49e-01 | 75.3% | 41.1% |
| 4a25B01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.64 | 47.0 | 4.06e-01 | 79.4% | 74.5% |
| 1vctA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.64 | 46.0 | 4.46e-01 | 75.3% | 78.9% |
| 1dd5A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.64 | 46.0 | 4.47e-01 | 76.3% | 87.2% |
| 4mhlA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.64 | 54.0 | 4.56e-01 | 91.8% | 93.8% |
| 1lvfB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 44.0 | 4.32e-01 | 74.2% | 91.3% |
| 6vq6G02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.62 | 46.0 | 3.67e-01 | 77.3% | 57.1% |
| 1vw4T01 | 6.10.330.20 | Special › Helix non-globular › Monooxygenase › | 0.61 | 43.0 | 4.14e-01 | 75.3% | 63.4% |
| 1sumB02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.60 | 43.0 | 4.10e-01 | 75.3% | 71.2% |
| 3rklA00 | 6.10.140.1640 | Special › Helix non-globular › Helix Hairpins › | 0.60 | 43.0 | 4.66e-01 | 76.3% | 88.7% |
| 2js5A00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.60 | 39.0 | 4.42e-01 | 80.4% | 90.1% |
| 1wa8A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.59 | 46.0 | 4.63e-01 | 83.5% | 80.8% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.59 | 44.0 | 4.67e-01 | 79.4% | 89.4% |
| 1jalA03 | 1.10.150.300 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Obg-related GTPase Ych/YyaF, coiled-coil domain | 0.59 | 42.0 | 4.49e-01 | 74.2% | 95.1% |
| 2nmlA00 | 3.30.2260.10 | Alpha Beta › 2-Layer Sandwich › ERH-like fold › Enhancer of rudimentary | 0.57 | 43.0 | 4.31e-01 | 100.0% | 77.0% |
| 1f45B00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.55 | 45.0 | 4.11e-01 | 90.7% | 92.5% |
| 2b3tB01 | 6.10.140.1980 | Special › Helix non-globular › Helix Hairpins › | 0.55 | 35.0 | 4.05e-01 | 89.7% | 96.9% |
| 2yyiA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.54 | 47.0 | 3.71e-01 | 97.9% | 87.2% |
| 8sbeA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.53 | 40.0 | 3.17e-01 | 79.4% | 88.8% |
| 2d2sA02 | 1.20.58.1220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, C-terminal helical domain | 0.53 | 42.0 | 4.18e-01 | 85.6% | 87.1% |
| 4finB01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.52 | 38.0 | 2.82e-01 | 78.4% | 39.3% |
ECOD (23)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3839497 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.78 | 50.0 | 5.33e-01 | 80.4% | 74.1% |
| 3941435 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.74 | 54.0 | 4.68e-01 | 77.3% | 94.0% |
| 3740490 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.73 | 51.0 | 3.84e-01 | 72.2% | 79.6% |
| 3805159 | 4099.1.1.11 ↗ | a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › Med14 | 0.73 | 47.0 | 4.66e-01 | 83.5% | 63.0% |
| 4615849 | 7013.1.1.1 ↗ | alpha bundles › Ribosome assembly factor Efg1-like › Ribosome assembly factor Efg1-like › Ribosome assembly factor Efg1-like › Efg1 | 0.73 | 55.0 | 4.39e-01 | 79.4% | 42.2% |
| 3237264 | 3755.4.1.82 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Snf7 | 0.72 | 51.0 | 4.58e-01 | 72.2% | 93.1% |
| 3736689 | 4207.1.2.1 ↗ | alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region › Med7 | 0.72 | 45.0 | 4.22e-01 | 76.3% | 53.0% |
| 988025 | 616.1.1.5 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › T6SS_Tsi2-like | 0.71 | 44.0 | 4.99e-01 | 78.4% | 80.3% |
| 3250598 | 633.6.1.2 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX | 0.70 | 55.0 | 4.53e-01 | 82.5% | 68.0% |
| 3631657 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.69 | 51.0 | 3.40e-01 | 81.4% | 22.4% |
| 4975039 | 1174.1.1.1 ↗ | alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 › TMEM175 | 0.68 | 57.0 | 4.48e-01 | 92.8% | 81.5% |
| 3872946 | 601.19.1.55 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › PF28139 | 0.68 | 52.0 | 3.43e-01 | 82.5% | 78.6% |
| 4024396 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.67 | 49.0 | 4.45e-01 | 77.3% | 97.8% |
| 2600 | 101.1.2.14 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_5 | 0.66 | 51.0 | 4.39e-01 | 81.4% | 58.9% |
| 3687766 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.66 | 54.0 | 4.08e-01 | 87.6% | 88.4% |
| 4396574 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.65 | 51.0 | 4.24e-01 | 82.5% | 83.5% |
| 3876829 | 3939.1.1.0 ↗ | alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain | 0.64 | 47.0 | 4.68e-01 | 80.4% | 74.0% |
| 4660205 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.62 | 48.0 | 4.30e-01 | 82.5% | 76.3% |
| 3250208 | 4207.1.2.1 ↗ | alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region › Med7 | 0.60 | 42.0 | 3.87e-01 | 77.3% | 53.8% |
| 3743538 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.58 | 42.0 | 4.31e-01 | 75.3% | 86.0% |
| 3595984 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.57 | 51.0 | 3.32e-01 | 100.0% | 82.0% |
| 3386010 | 2004.1.1.430 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran, ABC_tran_Xtn | 0.51 | 44.0 | 2.76e-01 | 95.9% | 47.0% |
| 3417475 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.51 | 43.0 | 2.93e-01 | 99.0% | 75.9% |