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CAKLQF020000022.1__CAH1091234.1__SAMEA5780031_03293__00052
Bact-VirCAKLQF020000022.1__CAH1091234.1__SAMEA5780031_03293__00052
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 31-176
Domain cluster:
representative
CATH (34)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4ozjA00 | 3.30.70.120 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.68 | 37.0 | 4.30e-01 | 88.4% | 73.1% |
| 3f6gA02 | 3.30.160.340 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.67 | 31.0 | 4.45e-01 | 78.8% | 98.4% |
| 2d5wA02 | 3.90.76.10 | Alpha Beta › Alpha-Beta Complex › Dipeptide-binding Protein; domain 1 › Dipeptide-binding Protein; Domain 1 | 0.65 | 47.0 | 5.19e-01 | 83.6% | 91.5% |
| 4noiA01 | 3.30.1360.10 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit | 0.64 | 42.0 | 4.84e-01 | 75.3% | 92.2% |
| 4bbyA05 | 3.30.300.330 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › | 0.64 | 43.0 | 4.87e-01 | 74.0% | 91.7% |
| 1nxiA00 | 3.30.70.970 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RraB-like | 0.64 | 47.0 | 4.89e-01 | 97.3% | 83.3% |
| 3rkxA02 | 3.30.930.10 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 | 0.63 | 53.0 | 4.78e-01 | 91.1% | 91.5% |
| 4r6uA03 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.62 | 37.0 | 4.30e-01 | 78.8% | 83.5% |
| 4f80A02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.60 | 35.0 | 4.17e-01 | 75.3% | 87.1% |
| 2rilA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.60 | 35.0 | 4.18e-01 | 70.5% | 87.4% |
| 2ftrA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.59 | 38.0 | 4.38e-01 | 70.5% | 90.3% |
| 4jb9H01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.59 | 43.0 | 4.50e-01 | 78.8% | 83.2% |
| 1e25A00 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.59 | 36.0 | 2.89e-01 | 93.2% | 31.7% |
| 3o4oB03 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.58 | 39.0 | 4.33e-01 | 78.8% | 89.9% |
| 2x1wL02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.57 | 37.0 | 4.17e-01 | 78.1% | 88.6% |
| 6dw1A00 | 2.70.170.10 | Mainly Beta › Distorted Sandwich › Acetylcholine Binding Protein; Chain: A, › Neurotransmitter-gated ion-channel ligand-binding domain | 0.55 | 41.0 | 3.65e-01 | 77.4% | 79.0% |
| 3jafA01 | 2.70.170.10 | Mainly Beta › Distorted Sandwich › Acetylcholine Binding Protein; Chain: A, › Neurotransmitter-gated ion-channel ligand-binding domain | 0.55 | 41.0 | 3.66e-01 | 78.1% | 78.7% |
| 2bj0A00 | 2.70.170.10 | Mainly Beta › Distorted Sandwich › Acetylcholine Binding Protein; Chain: A, › Neurotransmitter-gated ion-channel ligand-binding domain | 0.55 | 42.0 | 3.72e-01 | 78.8% | 79.3% |
| 2x8kA01 | 2.40.30.200 | Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › | 0.55 | 37.0 | 4.28e-01 | 85.6% | 95.2% |
| 6d6tA01 | 2.70.170.10 | Mainly Beta › Distorted Sandwich › Acetylcholine Binding Protein; Chain: A, › Neurotransmitter-gated ion-channel ligand-binding domain | 0.55 | 40.0 | 3.60e-01 | 76.7% | 79.0% |
| 1y8oA02 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.55 | 40.0 | 3.87e-01 | 76.0% | 90.0% |
| 4gafB03 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.54 | 36.0 | 4.00e-01 | 78.1% | 87.3% |
| 2lyxA00 | 3.10.450.390 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › Protein of unknown function DUF3889 | 0.53 | 31.0 | 3.77e-01 | 92.5% | 93.1% |
| 3rpfA00 | 3.90.1170.40 | Alpha Beta › Alpha-Beta Complex › Aldehyde Oxidoreductase; domain 3 › Molybdopterin biosynthesis MoaE subunit | 0.53 | 38.0 | 3.88e-01 | 74.7% | 88.3% |
| 4ec6A00 | 3.10.450.540 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.53 | 32.0 | 3.56e-01 | 95.2% | 77.1% |
| 1av5A00 | 3.30.428.10 | Alpha Beta › 2-Layer Sandwich › HIT family, subunit A › HIT-like | 0.53 | 35.0 | 3.93e-01 | 83.6% | 87.6% |
| 5a2fA02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.53 | 36.0 | 3.95e-01 | 76.7% | 89.3% |
| 6ofsA04 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.52 | 45.0 | 4.17e-01 | 92.5% | 91.3% |
| 3klxB00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.52 | 44.0 | 4.14e-01 | 93.2% | 98.3% |
| 1sz7A00 | 3.30.1380.20 | Alpha Beta › 2-Layer Sandwich › Muramoyl-pentapeptide Carboxypeptidase; domain 2 › Trafficking protein particle complex subunit 3 | 0.51 | 35.0 | 3.44e-01 | 76.7% | 63.5% |
| 2ab5B01 | 3.10.28.10 | Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases | 0.51 | 31.0 | 3.28e-01 | 78.8% | 67.2% |
| 6iy8A01 | 3.30.1380.20 | Alpha Beta › 2-Layer Sandwich › Muramoyl-pentapeptide Carboxypeptidase; domain 2 › Trafficking protein particle complex subunit 3 | 0.51 | 36.0 | 3.33e-01 | 74.0% | 55.6% |
| 3gcfA01 | 3.90.380.10 | Alpha Beta › Alpha-Beta Complex › Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 › Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 | 0.51 | 36.0 | 2.99e-01 | 71.2% | 69.3% |
| 5ejlA02 | 2.40.10.220 | Mainly Beta › Beta Barrel › Thrombin, subunit H › predicted glycosyltransferase like domains | 0.50 | 35.0 | 3.80e-01 | 89.0% | 84.7% |
ECOD (43)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3573665 | 327.11.2.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) | 0.67 | 40.0 | 4.97e-01 | 92.5% | 96.7% |
| 4014111 | 327.11.2.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) | 0.66 | 37.0 | 4.52e-01 | 70.5% | 84.2% |
| 3413500 | 304.6.1.1 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › FAD-oxidase_C | 0.64 | 43.0 | 3.49e-01 | 74.0% | 35.4% |
| 3604508 | 304.8.1.4 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NikR_C | 0.64 | 36.0 | 4.46e-01 | 89.7% | 90.0% |
| 4954449 | 310.3.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related | 0.63 | 41.0 | 4.86e-01 | 74.7% | 96.0% |
| 4100576 | 305.1.1.0 ↗ | a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase | 0.63 | 43.0 | 4.95e-01 | 74.7% | 100.0% |
| 3992359 | 331.4.1.0 ↗ | a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 | 0.62 | 39.0 | 4.63e-01 | 73.3% | 92.0% |
| 5040945 | 304.124.1.0 ↗ | a+b two layers › Alpha-beta plaits › Phage tail protein-like › Phage tail protein-like | 0.62 | 46.0 | 4.59e-01 | 76.7% | 98.0% |
| 5931 | 327.11.2.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1 | 0.62 | 39.0 | 4.46e-01 | 95.2% | 87.5% |
| 4086765 | 242.1.1.5 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › WhiA_N | 0.61 | 35.0 | 3.98e-01 | 77.4% | 72.7% |
| 3959045 | 305.1.1.0 ↗ | a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase | 0.61 | 46.0 | 4.97e-01 | 77.4% | 100.0% |
| 1264082 | 314.1.1.6 ↗ | a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › BPL_LplA_LipB | 0.61 | 51.0 | 4.56e-01 | 91.1% | 92.0% |
| 4683313 | 242.1.1.5 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › WhiA_N | 0.61 | 36.0 | 3.91e-01 | 78.1% | 69.2% |
| 4619723 | 305.1.1.1 ↗ | a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L | 0.60 | 43.0 | 4.68e-01 | 97.9% | 89.2% |
| 4061533 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.60 | 44.0 | 4.27e-01 | 76.0% | 91.3% |
| 3972904 | 310.3.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related | 0.59 | 38.0 | 4.39e-01 | 74.0% | 93.0% |
| 4393617 | 330.6.1.1 ↗ | a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer | 0.59 | 37.0 | 3.86e-01 | 92.5% | 68.5% |
| 5028136 | 242.1.1.7 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 | 0.59 | 35.0 | 3.84e-01 | 78.1% | 72.2% |
| None | — | 0.58 | 39.0 | 3.03e-01 | 75.3% | 32.1% | |
| 4403450 | 305.1.1.1 ↗ | a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L | 0.57 | 43.0 | 4.67e-01 | 78.8% | 95.0% |
| 4990439 | 304.116.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in release factor › Ferredoxin-like domain in release factor | 0.57 | 35.0 | 4.11e-01 | 91.1% | 89.0% |
| 3606930 | 310.3.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related | 0.57 | 40.0 | 4.54e-01 | 74.0% | 98.2% |
| 5047798 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.56 | 41.0 | 4.09e-01 | 76.0% | 95.5% |
| 3842698 | 2007.9.1.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain | 0.56 | 37.0 | 2.99e-01 | 75.3% | 32.1% |
| 2389463 | 873.1.1.5 ↗ | a+b complex topology › H-NOX domain › H-NOX domain › H-NOX domain › HNOB | 0.56 | 36.0 | 3.34e-01 | 72.6% | 50.3% |
| 3968643 | 241.1.1.8 ↗ | a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › DUF2170 | 0.55 | 46.0 | 4.80e-01 | 92.5% | 97.8% |
| 3723425 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.54 | 46.0 | 3.56e-01 | 91.8% | 53.5% |
| 3861272 | 304.47.1.5 ↗ | a+b two layers › Alpha-beta plaits › SEA domain › SEA domain › PF29544 | 0.54 | 36.0 | 4.08e-01 | 71.2% | 90.0% |
| 4021762 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.53 | 45.0 | 2.98e-01 | 92.5% | 27.4% |
| 3636645 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.53 | 45.0 | 3.55e-01 | 92.5% | 55.9% |
| 3702874 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.53 | 38.0 | 3.94e-01 | 75.3% | 85.7% |
| 3197890 | 304.61.1.2 ↗ | a+b two layers › Alpha-beta plaits › Aldoxime dehydratase › Aldoxime dehydratase › Monooxy_af470-like | 0.52 | 39.0 | 3.42e-01 | 76.7% | 71.6% |
| 4975726 | 873.1.1.1 ↗ | a+b complex topology › H-NOX domain › H-NOX domain › H-NOX domain › V4R | 0.52 | 37.0 | 3.44e-01 | 74.7% | 57.8% |
| 4943901 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.52 | 35.0 | 3.92e-01 | 76.7% | 87.0% |
| 4948955 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.52 | 29.0 | 2.86e-01 | 86.3% | 47.1% |
| 4201044 | 304.109.1.10 ↗ | a+b two layers › Alpha-beta plaits › Ribosomal proteins S24e, L23 and L15e › Ribosomal proteins S24e, L23 and L15e › PF27137 | 0.52 | 37.0 | 4.03e-01 | 76.7% | 88.3% |
| 3435849 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.52 | 27.0 | 3.44e-01 | 84.9% | 84.1% |
| 3943477 | 310.3.1.9 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related › P2_Phage_GpR | 0.52 | 39.0 | 4.11e-01 | 78.1% | 100.0% |
| 3794217 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.51 | 44.0 | 2.97e-01 | 91.8% | 25.5% |
| 3239062 | 312.1.1.2 ↗ | a+b three layers › HIT-like › HIT-related › HIT-related › HIT | 0.51 | 35.0 | 3.65e-01 | 83.6% | 76.2% |
| 4184227 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.51 | 41.0 | 4.00e-01 | 85.6% | 84.2% |
| 4949372 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.50 | 39.0 | 3.94e-01 | 82.9% | 83.3% |
| 5083099 | 873.1.1.1 ↗ | a+b complex topology › H-NOX domain › H-NOX domain › H-NOX domain › V4R | 0.50 | 35.0 | 3.41e-01 | 72.6% | 63.7% |