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CAKLQF020000022.1__CAH1091331.1__SAMEA5780031_03329__00084

Bact-Vir

CAKLQF020000022.1__CAH1091331.1__SAMEA5780031_03329__00084

Identity

Kingdom:
phage

Quality

92.0 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 5-85
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03653.19 best UPF0093 95.2 6.50e-27 98.8% 48.6%
CATH (67)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4e4eA01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.90 75.0 7.97e-01 91.4% 98.6%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.89 78.0 5.39e-01 92.6% 32.6%
1jkvA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.88 69.0 5.01e-01 81.5% 74.6%
1cxzB00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.87 72.0 7.02e-01 86.4% 81.4%
2wb7A03 1.20.120.870 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain 0.87 64.0 5.27e-01 79.0% 45.6%
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.87 73.0 7.71e-01 93.8% 100.0%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.87 65.0 6.28e-01 80.2% 70.3%
4dylA02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.87 79.0 7.43e-01 96.3% 100.0%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.87 75.0 5.04e-01 92.6% 28.0%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.86 73.0 6.57e-01 90.1% 79.4%
3m7gA02 1.10.8.1010 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.85 65.0 6.11e-01 82.7% 67.4%
1ku9A02 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.85 64.0 7.14e-01 82.7% 100.0%
4mtxD00 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.85 66.0 6.21e-01 84.0% 69.5%
1tjlA00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.85 70.0 5.66e-01 92.6% 49.0%
4egwA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.84 73.0 6.34e-01 92.6% 64.7%
3lnnB03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.84 66.0 7.14e-01 93.8% 100.0%
3a8pA02 6.10.140.680 Special › Helix non-globular › Helix Hairpins › 0.84 73.0 6.45e-01 95.1% 66.7%
2dw4A03 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.82 71.0 6.58e-01 92.6% 81.2%
2r9iA00 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.82 63.0 6.68e-01 82.7% 91.5%
3ajwA00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.82 71.0 5.95e-01 93.8% 61.2%
2rkhA02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.82 61.0 6.33e-01 79.0% 82.9%
4ijjB00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.82 66.0 5.59e-01 92.6% 53.8%
1j30A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.80 64.0 5.22e-01 84.0% 52.5%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.80 70.0 6.71e-01 92.6% 84.4%
1a36A04 1.10.132.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.80 64.0 4.94e-01 92.6% 40.0%
3g67A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.80 68.0 4.92e-01 91.4% 36.6%
1dkxA02 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.79 54.0 5.43e-01 70.4% 72.5%
6grjB01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.79 67.0 4.47e-01 93.8% 32.4%
2lm9A00 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 62.0 5.91e-01 86.4% 72.9%
1h7cA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 67.0 6.16e-01 93.8% 85.4%
5z7qA00 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.76 69.0 5.30e-01 98.8% 81.2%
1vf7A03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.76 54.0 6.09e-01 80.2% 100.0%
1qu7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.76 63.0 4.58e-01 91.4% 65.6%
1kmiZ02 1.10.287.500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.76 64.0 5.47e-01 95.1% 59.0%
3rkgA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.76 68.0 5.28e-01 96.3% 49.4%
2gl2B00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.75 66.0 5.98e-01 96.3% 86.2%
4mh6A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.75 63.0 5.07e-01 92.6% 91.8%
3k29A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.75 67.0 5.28e-01 97.5% 53.4%
4l8jA04 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.75 52.0 5.85e-01 90.1% 100.0%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.74 58.0 5.22e-01 86.4% 62.0%
2g38B00 1.20.1260.20 Mainly Alpha › Up-down Bundle › Ferritin › PPE superfamily 0.74 61.0 4.78e-01 91.4% 42.8%
4h63K00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.74 63.0 5.95e-01 95.1% 77.6%
2uv8A07 6.10.140.1410 Special › Helix non-globular › Helix Hairpins › 0.73 51.0 5.06e-01 72.8% 71.8%
2vkzA02 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.73 51.0 3.51e-01 72.8% 23.3%
6tkvA01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.72 57.0 6.09e-01 90.1% 100.0%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.72 60.0 4.96e-01 91.4% 61.2%
3fhnA01 6.10.280.210 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain A 0.72 56.0 4.26e-01 87.7% 36.4%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.72 59.0 6.11e-01 90.1% 100.0%
4iggA01 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.71 54.0 5.76e-01 90.1% 98.5%
2xubA05 6.10.140.1450 Special › Helix non-globular › Helix Hairpins › 0.71 62.0 5.90e-01 96.3% 92.7%
3fppA03 6.10.140.1990 Special › Helix non-globular › Helix Hairpins › 0.71 59.0 5.78e-01 91.4% 100.0%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.70 59.0 5.96e-01 91.4% 93.9%
5h5mA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.70 55.0 4.74e-01 85.2% 53.8%
6fmhB01 1.10.3160.10 Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 0.70 56.0 4.31e-01 85.2% 45.3%
2bdeA03 1.20.58.1160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 55.0 5.69e-01 88.9% 92.2%
3s84A02 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.69 51.0 4.14e-01 80.2% 40.8%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 54.0 5.73e-01 90.1% 100.0%
2rdcA00 1.10.287.800 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 0.69 61.0 5.19e-01 100.0% 62.4%
4gzrB00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.68 56.0 5.77e-01 90.1% 93.5%
3zciA00 1.20.58.1660 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 60.0 4.59e-01 100.0% 54.5%
1zhcA00 6.10.280.50 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 48.0 4.95e-01 84.0% 80.3%
4h63H01 1.20.58.1710 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 52.0 5.43e-01 85.2% 100.0%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 58.0 5.01e-01 98.8% 80.5%
4gltA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.65 51.0 4.60e-01 85.2% 61.4%
2qyuA02 1.25.40.300 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Putative secreted effector protein 0.65 40.0 3.04e-01 100.0% 25.6%
3r6nB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 57.0 4.18e-01 100.0% 37.1%
5mmjn01 1.10.287.1480 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.53 45.0 4.42e-01 100.0% 96.6%
ECOD (76)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4928931 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.90 72.0 5.87e-01 85.2% 48.6%
3917888 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.90 77.0 6.71e-01 91.4% 63.5%
4041347 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.90 79.0 7.05e-01 93.8% 70.0%
5048590 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.89 79.0 7.01e-01 93.8% 70.9%
3290472 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.89 83.0 6.47e-01 100.0% 50.6%
3215342 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.89 78.0 7.38e-01 93.8% 82.1%
4247116 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.88 78.0 6.96e-01 95.1% 69.1%
3996264 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.88 79.0 6.03e-01 96.3% 45.3%
3712648 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.88 77.0 5.67e-01 92.6% 47.9%
4219465 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.88 78.0 6.91e-01 93.8% 69.1%
4016635 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.87 75.0 6.96e-01 92.6% 77.0%
3209252 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.87 77.0 5.37e-01 95.1% 33.2%
3965830 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.86 75.0 6.93e-01 100.0% 75.0%
3453933 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.86 77.0 6.89e-01 96.3% 71.8%
4937862 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.86 76.0 6.81e-01 95.1% 70.9%
3733141 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.86 74.0 6.01e-01 92.6% 53.1%
3932665 193.1.1.0 alpha bundles › CH domain-like › Calponin-homology domain-like › Calponin-homology domain-like 0.86 74.0 5.04e-01 92.6% 29.6%
3253223 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.85 67.0 5.89e-01 84.0% 58.3%
3179070 3291.1.1.1 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 0.85 76.0 6.03e-01 96.3% 51.6%
1171038 3755.3.1.148 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › CT398_CC 0.85 73.0 5.45e-01 92.6% 40.3%
1276361 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.85 74.0 6.49e-01 93.8% 65.5%
2337262 1189.1.1.1 alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › Trypan_glycop 0.84 78.0 7.27e-01 98.8% 89.7%
3796544 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.84 72.0 5.00e-01 92.6% 30.8%
3331738 633.4.1.0 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor 0.84 67.0 6.05e-01 84.0% 64.8%
3627942 3755.4.1.1 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PI3K_P85_iSH2 0.83 79.0 5.93e-01 100.0% 83.4%
5041194 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.83 75.0 5.95e-01 97.5% 56.1%
3487846 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.83 73.0 5.94e-01 96.3% 53.1%
3788609 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.83 74.0 6.63e-01 100.0% 70.9%
5063166 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.83 72.0 6.54e-01 96.3% 71.4%
3763454 5086.1.1.87 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING 0.83 71.0 6.16e-01 91.4% 62.5%
3935140 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.83 76.0 5.73e-01 98.8% 83.9%
4586824 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.83 72.0 5.09e-01 93.8% 34.3%
3964187 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.82 69.0 6.98e-01 90.1% 100.0%
3484694 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.82 75.0 4.89e-01 100.0% 55.2%
3902100 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.82 70.0 6.91e-01 92.6% 100.0%
3550436 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.82 72.0 6.60e-01 96.3% 74.0%
3477777 4177.1.1.12 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FAM92 0.81 71.0 4.99e-01 93.8% 33.6%
3795373 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.81 70.0 4.89e-01 92.6% 32.1%
3556027 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.81 69.0 6.82e-01 92.6% 100.0%
3987659 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.81 71.0 5.12e-01 96.3% 35.8%
3855461 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.81 69.0 6.80e-01 92.6% 100.0%
5073085 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.81 72.0 5.66e-01 97.5% 49.4%
3359919 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.81 73.0 6.64e-01 100.0% 82.4%
3934585 3755.3.1.465 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A 0.81 72.0 5.76e-01 96.3% 61.3%
3671258 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.80 69.0 5.84e-01 92.6% 57.7%
4950969 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.80 67.0 4.09e-01 95.1% 15.5%
3520611 3291.1.1.1 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 0.80 71.0 5.36e-01 96.3% 44.3%
3470739 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.80 70.0 5.11e-01 96.3% 36.3%
3170506 4177.1.1.14 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_2 0.79 68.0 4.79e-01 93.8% 32.5%
4957467 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.79 59.0 3.94e-01 92.6% 21.7%
3613914 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.78 64.0 6.62e-01 88.9% 100.0%
3266812 3291.1.1.211 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › EMC3_TMCO1 0.78 71.0 5.53e-01 96.3% 81.9%
3279027 150.8.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE › PPE 0.78 66.0 5.11e-01 92.6% 49.1%
3995294 1065.1.1.0 alpha bundles › SPX domain › SPX domain › SPX domain 0.78 65.0 5.61e-01 91.4% 68.0%
3907547 4177.1.1.10 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › GMIP-like_FCH 0.77 65.0 4.38e-01 92.6% 26.0%
3498716 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.77 69.0 6.19e-01 97.5% 74.5%
3712573 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.75 65.0 5.45e-01 96.3% 82.1%
3170937 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.75 63.0 4.33e-01 92.6% 27.3%
3530949 3291.1.1.231 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PF27745 0.75 69.0 5.52e-01 100.0% 90.0%
3947823 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.75 62.0 5.48e-01 91.4% 74.2%
5053066 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.75 68.0 4.84e-01 100.0% 41.3%
4210642 3755.1.1.12 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › CheZ 0.75 64.0 5.52e-01 96.3% 61.5%
4992864 4323.1.1.0 alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C 0.75 65.0 5.21e-01 97.5% 51.2%
3958131 611.4.1.0 alpha bundles › N-cbl like › PG0775 C-terminal domain-like › PG0775 C-terminal domain-like 0.74 62.0 5.24e-01 91.4% 55.6%
3584613 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.74 64.0 4.36e-01 97.5% 67.3%
3282043 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.73 62.0 6.12e-01 91.4% 91.8%
3194153 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.73 60.0 5.70e-01 88.9% 76.8%
3717860 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.72 50.0 4.83e-01 71.6% 64.4%
3971026 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.71 59.0 5.12e-01 92.6% 66.4%
4016645 5086.1.1.176 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › DUF202 0.70 58.0 5.15e-01 90.1% 66.1%
4984270 4.1.1.481 beta barrels › SH3 › SH3 › SH3 › MS_channel_1st_1 0.69 50.0 4.68e-01 76.5% 70.0%
3592317 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.68 59.0 4.17e-01 100.0% 49.5%
3186617 2004.1.1.30 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.67 57.0 3.85e-01 96.3% 83.6%
3712635 5069.1.3.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.67 51.0 4.89e-01 82.7% 70.5%
4595288 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.63 52.0 4.41e-01 92.6% 55.0%
4949270 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.61 45.0 4.06e-01 81.5% 57.3%
D2 medium residues 86-150
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03653.19 best UPF0093 65.7 8.10e-18 100.0% 42.5%
CATH (56)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2gd5A00 6.10.140.1230 Special › Helix non-globular › Helix Hairpins › 0.84 77.0 5.88e-01 100.0% 79.6%
2rd0B00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.83 75.0 5.74e-01 98.5% 48.2%
2q1kA00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.83 63.0 6.94e-01 95.4% 100.0%
2xubA05 6.10.140.1450 Special › Helix non-globular › Helix Hairpins › 0.82 72.0 6.24e-01 95.4% 94.8%
4hwdD00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.82 68.0 6.06e-01 92.3% 65.6%
6r1nA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.81 73.0 6.20e-01 98.5% 68.0%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.81 68.0 5.64e-01 98.5% 54.2%
1evsA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.81 75.0 5.44e-01 100.0% 60.7%
3na7A00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.81 72.0 4.81e-01 98.5% 30.0%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.80 70.0 6.49e-01 96.9% 81.5%
5y06A01 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.79 71.0 4.80e-01 98.5% 29.3%
3dyjA02 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.79 67.0 5.11e-01 95.4% 41.1%
2o57A01 1.10.287.840 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Mycolic acid cyclopropane synthase domain like 0.79 60.0 5.07e-01 96.9% 50.5%
1b3qA01 1.10.287.560 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Histidine kinase CheA-like, homodimeric domain 0.78 61.0 6.26e-01 95.4% 90.3%
2fb5A01 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.77 67.0 6.55e-01 98.5% 98.6%
2bdeA03 1.20.58.1160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 67.0 6.34e-01 96.9% 85.7%
4cqiA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 66.0 5.63e-01 96.9% 77.6%
1yg2A02 6.10.140.190 Special › Helix non-globular › Helix Hairpins › 0.77 65.0 5.82e-01 93.8% 82.2%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.77 65.0 5.65e-01 95.4% 69.6%
1u7lA02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.77 68.0 4.88e-01 98.5% 50.3%
4lwsA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.76 66.0 5.78e-01 98.5% 68.0%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.76 70.0 5.27e-01 100.0% 58.5%
4h63H01 1.20.58.1710 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 64.0 6.26e-01 95.4% 84.7%
3t98B00 6.10.140.1350 Special › Helix non-globular › Helix Hairpins › 0.76 64.0 5.89e-01 95.4% 76.7%
1a36A04 1.10.132.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.76 64.0 4.74e-01 96.9% 38.3%
1fntc01 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.75 63.0 4.58e-01 95.4% 44.1%
3r84B00 6.10.280.160 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 0.75 60.0 5.62e-01 87.7% 97.5%
2ke4A00 6.10.140.470 Special › Helix non-globular › Helix Hairpins › 0.75 64.0 5.63e-01 96.9% 86.7%
4biuE01 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.75 64.0 5.64e-01 98.5% 67.3%
1grjA01 1.10.287.180 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain 0.74 62.0 6.02e-01 93.8% 94.6%
1i4dA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.74 64.0 4.67e-01 100.0% 78.7%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.74 61.0 5.50e-01 92.3% 70.3%
6v9zA02 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.74 64.0 4.06e-01 98.5% 21.2%
4xpwA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.74 61.0 4.96e-01 95.4% 48.1%
2etnB01 1.10.287.180 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain 0.73 63.0 6.03e-01 100.0% 92.1%
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 59.0 5.79e-01 93.8% 98.6%
1ucuA01 6.10.280.190 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 60.0 5.98e-01 95.4% 100.0%
2qe7G01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.72 61.0 5.46e-01 98.5% 71.1%
1ku9A02 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.72 59.0 5.99e-01 93.8% 100.0%
4gczA03 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.72 58.0 5.82e-01 92.3% 95.4%
2fcwA00 1.20.81.10 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain 0.70 59.0 5.12e-01 98.5% 64.2%
4dylA02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.70 58.0 5.28e-01 96.9% 71.3%
1j30A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.69 58.0 4.61e-01 96.9% 45.4%
4b6xA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 58.0 5.80e-01 98.5% 92.8%
2bduA02 1.10.150.340 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Pyrimidine 5'-nucleotidase (UMPH-1), N-terminal domain 0.69 51.0 4.89e-01 83.1% 68.9%
6xm1A02 3.90.830.10 Alpha Beta › Alpha-Beta Complex › Syntaxin Binding Protein 1; Chain A, domain 2 › Sec1/Munc18 (SM) protein, domain 3a 0.68 55.0 4.65e-01 95.4% 52.2%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.68 59.0 5.49e-01 100.0% 85.9%
2wdqD00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.67 55.0 4.71e-01 92.3% 62.9%
4lunU00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.66 56.0 3.59e-01 95.4% 21.5%
3purA03 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 51.0 4.43e-01 92.3% 57.3%
1kfdA02 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.60 51.0 4.96e-01 96.9% 90.1%
6qumQ00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.60 51.0 4.92e-01 98.5% 89.2%
3o39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.56 47.0 4.22e-01 98.5% 69.8%
1jeyB03 1.10.1600.10 Mainly Alpha › Orthogonal Bundle › Ku70; Chain: A; domain 4 › 0.52 39.0 3.49e-01 93.8% 53.9%
2au5A00 1.20.120.590 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › EF2947-like 0.52 44.0 3.61e-01 100.0% 91.5%
6bz0D01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.51 44.0 3.07e-01 98.5% 47.8%
ECOD (62)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3838108 192.29.1.123 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › UPF0093 0.99 94.0 6.89e-01 98.5% 45.5%
3385460 5069.1.1.74 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › UPF0093 0.94 88.0 6.45e-01 98.5% 43.3%
4217297 192.29.1.123 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › UPF0093 0.91 86.0 6.37e-01 100.0% 44.8%
3220596 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.84 75.0 6.17e-01 98.5% 59.1%
3692897 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.83 74.0 7.08e-01 96.9% 90.7%
3994518 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.83 76.0 5.24e-01 100.0% 74.0%
3711734 3755.3.1.297 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF9 0.83 73.0 5.34e-01 96.9% 64.8%
3283457 150.5.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 0.82 74.0 6.33e-01 98.5% 80.0%
4943532 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.82 72.0 7.01e-01 95.4% 97.1%
3617899 192.29.1.181 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › TMEM120A-B 0.82 69.0 6.31e-01 92.3% 97.6%
3593287 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.82 72.0 5.69e-01 96.9% 53.8%
3752758 3755.3.1.467 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DRC7_C 0.81 73.0 5.54e-01 100.0% 53.0%
3906810 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.81 71.0 5.44e-01 95.4% 63.6%
4303085 3755.3.1.467 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DRC7_C 0.81 73.0 5.92e-01 100.0% 65.8%
3892960 3291.1.1.86 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PL48 0.81 73.0 5.65e-01 100.0% 90.7%
3608116 5086.1.1.177 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › KIF9 0.81 71.0 5.44e-01 96.9% 65.5%
3573035 109.4.1.3370 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PL48 0.81 73.0 5.68e-01 100.0% 94.8%
4572974 3922.1.1.79 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › SAP130_C 0.81 73.0 5.95e-01 98.5% 58.3%
3393794 3922.1.1.211 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DRC7_C 0.81 71.0 5.58e-01 98.5% 56.3%
3576448 3291.1.1.180 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › TMEM120A-B 0.81 68.0 5.97e-01 92.3% 69.5%
4946897 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.80 69.0 4.96e-01 98.5% 35.3%
3939816 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.80 69.0 5.56e-01 93.8% 62.5%
3861615 150.1.1.190 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › SAP130_C 0.80 73.0 6.21e-01 98.5% 68.0%
3484074 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.80 71.0 5.50e-01 98.5% 52.1%
2325068 3755.3.1.148 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › CT398_CC 0.79 71.0 5.04e-01 98.5% 35.6%
5040661 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.78 68.0 6.63e-01 98.5% 87.1%
3936581 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.78 69.0 4.89e-01 98.5% 41.1%
3595002 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.78 68.0 5.93e-01 98.5% 72.0%
3599499 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.78 69.0 5.23e-01 98.5% 44.7%
3716432 1075.4.1.2 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane_2 0.77 67.0 4.14e-01 95.4% 25.1%
3725506 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.77 65.0 5.49e-01 95.4% 68.2%
2337262 1189.1.1.1 alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › Trypan_glycop 0.76 66.0 5.77e-01 96.9% 71.1%
5050356 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.76 65.0 6.34e-01 95.4% 98.6%
4001635 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.76 66.0 5.24e-01 100.0% 100.0%
3646439 192.8.1.263 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › DUF7615 0.75 68.0 6.18e-01 100.0% 91.8%
3216366 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.75 64.0 4.80e-01 98.5% 40.6%
4684 192.15.1.2 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Mod_r 0.75 63.0 6.31e-01 93.8% 96.9%
3794663 604.3.1.27 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › EMC4 0.74 63.0 5.44e-01 98.5% 61.0%
1549356 601.14.1.1 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.74 61.0 4.96e-01 95.4% 48.1%
3449357 150.1.1.110 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › DUF7358 0.74 64.0 4.77e-01 100.0% 44.1%
3389152 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.72 61.0 4.89e-01 95.4% 47.7%
4001943 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.71 62.0 5.09e-01 98.5% 54.2%
4775818 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.71 60.0 4.34e-01 96.9% 39.5%
3924838 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.71 59.0 4.11e-01 98.5% 27.9%
4142346 5086.1.1.87 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING 0.71 59.0 5.09e-01 96.9% 74.5%
4680153 7015.1.1.1 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › DHHC 0.71 61.0 4.81e-01 98.5% 48.6%
3997950 5069.1.3.56 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › GOST_TM 0.70 57.0 5.19e-01 95.4% 66.7%
3494783 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.70 60.0 4.74e-01 98.5% 81.4%
4805104 601.19.1.1 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Apolipoprotein 0.70 59.0 5.56e-01 98.5% 83.1%
3385950 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.70 59.0 5.86e-01 98.5% 90.0%
5079216 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.70 60.0 4.68e-01 100.0% 88.0%
5040119 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.69 56.0 5.81e-01 92.3% 100.0%
3452856 3755.4.1.17 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Rx_N 0.69 58.0 4.70e-01 98.5% 54.8%
4982132 5069.1.3.135 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DUF5985 0.69 55.0 5.01e-01 93.8% 64.9%
2323907 212.1.1.24 a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Morc6_S5 0.68 59.0 4.12e-01 100.0% 59.0%
5077354 2004.5.1.0 a/b three-layered sandwiches › P-loop domains-like › Differentially expressed in normal cells and neoplasia (DENN) domain › Differentially expressed in normal cells and neoplasia (DENN) domain 0.67 50.0 3.27e-01 80.0% 22.2%
3899274 109.4.1.108 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CTNNBL 0.66 54.0 3.23e-01 95.4% 12.4%
3903963 192.29.1.225 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › TRC8_N 0.65 56.0 5.49e-01 98.5% 94.3%
3929028 5054.1.1.8 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.63 52.0 3.36e-01 100.0% 28.6%
5026085 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.62 53.0 4.56e-01 98.5% 73.1%
4200274 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.62 50.0 4.36e-01 92.3% 65.7%
3283686 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.61 48.0 4.79e-01 93.8% 87.1%