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CAKLQF020000025.1__CAH1092183.1__SAMEA5780031_03518__00055
Bact-VirCAKLQF020000025.1__CAH1092183.1__SAMEA5780031_03518__00055
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 92-233
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03600.23 best | CitMHS | 54.4 | 1.50e-14 | 93.7% | 35.7% |
CATH (29)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5d0yA00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.67 | 51.0 | 4.93e-01 | 86.6% | 72.3% |
| 4dylA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.61 | 45.0 | 3.74e-01 | 77.5% | 81.2% |
| 6klvB00 | 1.20.810.10 | Mainly Alpha › Up-down Bundle › Cytochrome Bc1 Complex; Chain C › Cytochrome Bc1 Complex; Chain C | 0.60 | 51.0 | 3.72e-01 | 92.3% | 62.8% |
| 3ezhA00 | 1.20.120.960 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase NarX, sensor domain | 0.59 | 43.0 | 4.70e-01 | 85.2% | 93.0% |
| 3ripA02 | 1.20.120.1900 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Gamma-tubulin complex, C-terminal domain | 0.59 | 45.0 | 3.65e-01 | 81.0% | 67.0% |
| 4k0dA00 | 1.20.120.1730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.58 | 45.0 | 4.56e-01 | 81.7% | 88.1% |
| 2bl2A00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.58 | 40.0 | 3.90e-01 | 71.1% | 62.8% |
| 1n81A00 | 1.10.3030.10 | Mainly Alpha › Orthogonal Bundle › Gametocyte protein Pfg27 › Gametocyte protein Pfg27 | 0.58 | 44.0 | 4.02e-01 | 79.6% | 91.4% |
| 4o6yB00 | 1.20.120.1770 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.58 | 48.0 | 4.23e-01 | 90.1% | 87.2% |
| 4etrB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.57 | 40.0 | 4.29e-01 | 71.1% | 91.0% |
| 2gscC00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.57 | 34.0 | 3.76e-01 | 73.2% | 73.6% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.56 | 40.0 | 4.24e-01 | 73.9% | 84.4% |
| 5zw7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.56 | 39.0 | 3.83e-01 | 76.1% | 65.8% |
| 4iggB02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.56 | 42.0 | 4.54e-01 | 79.6% | 96.7% |
| 6gpxB00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.56 | 42.0 | 3.44e-01 | 78.2% | 89.0% |
| 5tgzA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.56 | 44.0 | 3.53e-01 | 84.5% | 83.9% |
| 1eq1A00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.55 | 45.0 | 4.26e-01 | 86.6% | 82.5% |
| 2azjA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.54 | 45.0 | 3.62e-01 | 89.4% | 77.9% |
| 4e40A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.54 | 39.0 | 3.25e-01 | 73.2% | 79.6% |
| 2fp1B00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.54 | 39.0 | 3.78e-01 | 76.1% | 98.2% |
| 4od4A01 | 1.10.357.140 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › UbiA prenyltransferase | 0.54 | 43.0 | 4.23e-01 | 86.6% | 92.9% |
| 3we9A00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.53 | 43.0 | 3.67e-01 | 90.1% | 74.5% |
| 1u7gA00 | 1.10.3430.10 | Mainly Alpha › Orthogonal Bundle › Ammonium transporter fold › Ammonium transporter AmtB like domains | 0.52 | 43.0 | 3.18e-01 | 90.1% | 93.7% |
| 7twaC00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.52 | 39.0 | 3.39e-01 | 78.2% | 81.0% |
| 2p61A00 | 1.20.120.490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain | 0.51 | 36.0 | 3.92e-01 | 78.2% | 89.5% |
| 6cnzF00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.51 | 37.0 | 3.60e-01 | 74.6% | 96.8% |
| 4zvaA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.51 | 36.0 | 3.58e-01 | 81.0% | 68.5% |
| 1jadA00 | 1.20.1230.10 | Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain | 0.51 | 38.0 | 3.19e-01 | 78.2% | 78.1% |
| 5ts9B00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.51 | 38.0 | 3.64e-01 | 77.5% | 96.9% |
ECOD (43)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| None | — | 0.99 | 98.0 | 6.55e-01 | 100.0% | 33.5% | |
| 4622106 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.96 | 94.0 | 6.32e-01 | 100.0% | 34.5% |
| 4031025 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.94 | 91.0 | 6.09e-01 | 100.0% | 35.5% |
| 3385846 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.91 | 88.0 | 5.93e-01 | 100.0% | 31.9% |
| 4979062 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.80 | 75.0 | 5.23e-01 | 100.0% | 43.8% |
| 4944772 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.80 | 74.0 | 5.16e-01 | 100.0% | 45.0% |
| 3904424 | 3355.1.1.21 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_sulph_symp, CitMHS | 0.77 | 70.0 | 4.74e-01 | 98.6% | 37.3% |
| 5007958 | 3355.1.1.4 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › DctM | 0.75 | 70.0 | 4.79e-01 | 100.0% | 52.7% |
| 4600825 | 3355.1.1.4 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › DctM | 0.75 | 70.0 | 4.91e-01 | 100.0% | 43.8% |
| 4217961 | 3355.1.1.4 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › DctM | 0.74 | 68.0 | 4.72e-01 | 100.0% | 41.3% |
| 3941743 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.73 | 68.0 | 4.79e-01 | 100.0% | 35.4% |
| 3798724 | 1075.1.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane | 0.65 | 52.0 | 4.30e-01 | 85.9% | 71.2% |
| 3592441 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.64 | 49.0 | 4.76e-01 | 80.3% | 90.6% |
| 3171073 | 145.1.1.3 ↗ | alpha arrays › F-box domain › F-box domain › F-box domain › F-box-like | 0.63 | 35.0 | 3.85e-01 | 78.9% | 64.3% |
| 3974692 | 1026.1.1.0 ↗ | alpha bundles › Rev protein › Rev protein › Rev protein | 0.63 | 46.0 | 4.47e-01 | 76.1% | 100.0% |
| 3961587 | 191.1.1.1 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_1 | 0.63 | 50.0 | 5.02e-01 | 84.5% | 100.0% |
| 3235811 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.61 | 44.0 | 4.17e-01 | 76.1% | 80.6% |
| 3969049 | 601.4.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › 4HB_MCP_1 | 0.59 | 46.0 | 4.39e-01 | 82.4% | 79.4% |
| 3673192 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.59 | 49.0 | 4.64e-01 | 90.1% | 93.5% |
| 1406524 | 601.4.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › NIT | 0.57 | 48.0 | 4.57e-01 | 90.8% | 94.6% |
| 2464258 | 3620.1.1.1 ↗ | alpha bundles › Factor H-binding protein BbCRASP-1 › Factor H-binding protein BbCRASP-1 › Factor H-binding protein BbCRASP-1 › PFam54_60 | 0.56 | 47.0 | 4.12e-01 | 89.4% | 83.3% |
| 3287705 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.56 | 44.0 | 3.78e-01 | 83.8% | 71.3% |
| 3909550 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.56 | 36.0 | 3.63e-01 | 73.2% | 63.4% |
| 3317710 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.55 | 41.0 | 4.10e-01 | 78.2% | 83.3% |
| 4023330 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.55 | 42.0 | 3.99e-01 | 81.7% | 80.0% |
| 3935953 | 3615.1.1.0 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain | 0.55 | 37.0 | 3.80e-01 | 73.9% | 71.1% |
| 3399701 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.55 | 37.0 | 3.82e-01 | 75.4% | 70.0% |
| 3412240 | 174.1.1.33 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Erg28 | 0.54 | 36.0 | 3.76e-01 | 76.1% | 73.1% |
| 3686877 | 5069.1.1.7 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 | 0.54 | 42.0 | 3.72e-01 | 83.1% | 67.4% |
| 3227690 | 5050.1.1.8 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 | 0.54 | 47.0 | 4.00e-01 | 95.8% | 73.2% |
| 3917126 | 174.1.1.33 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Erg28 | 0.54 | 36.0 | 3.61e-01 | 76.8% | 64.7% |
| 3936049 | 5069.1.1.7 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 | 0.54 | 43.0 | 3.72e-01 | 89.4% | 73.5% |
| 3796800 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.53 | 35.0 | 3.70e-01 | 77.5% | 73.1% |
| 3640095 | 3615.1.1.0 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain | 0.53 | 32.0 | 3.44e-01 | 73.9% | 68.0% |
| 4055 | 164.1.1.1 ↗ | alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › CM_2 | 0.52 | 39.0 | 3.73e-01 | 77.5% | 96.4% |
| 5071165 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.52 | 39.0 | 3.89e-01 | 78.2% | 76.7% |
| 3527434 | 6006.1.1.6 ↗ | extended segments › Voltage gated calcium channel IQ domain › Voltage gated calcium channel IQ domain › Voltage gated calcium channel IQ domain › PF27661 | 0.52 | 42.0 | 4.07e-01 | 90.1% | 77.4% |
| 3400366 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.51 | 36.0 | 3.67e-01 | 77.5% | 72.9% |
| 3270906 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.51 | 46.0 | 3.23e-01 | 100.0% | 73.7% |
| 3625011 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.50 | 36.0 | 3.54e-01 | 77.5% | 67.7% |
| 3525698 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.50 | 34.0 | 3.55e-01 | 74.6% | 72.6% |
| 3934423 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.50 | 46.0 | 3.46e-01 | 100.0% | 82.3% |
| 3594969 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.50 | 43.0 | 3.90e-01 | 93.7% | 69.2% |
D2
high
residues 316-436
Domain cluster:
representative
CATH (14)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4mndA02 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.63 | 44.0 | 3.81e-01 | 72.7% | 51.8% |
| 6lumG01 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.59 | 42.0 | 4.34e-01 | 72.7% | 91.1% |
| 1t33A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.59 | 49.0 | 4.53e-01 | 90.9% | 88.0% |
| 4wpcA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.58 | 41.0 | 3.15e-01 | 71.9% | 71.4% |
| 3sqiA01 | 1.10.150.540 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › | 0.56 | 39.0 | 4.17e-01 | 70.2% | 88.9% |
| 1cpcA00 | 1.10.490.20 | Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins | 0.55 | 37.0 | 3.36e-01 | 71.9% | 51.2% |
| 4iu9B02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.54 | 43.0 | 3.69e-01 | 86.0% | 60.6% |
| 3r3uA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.54 | 46.0 | 3.50e-01 | 95.9% | 93.8% |
| 1a41A02 | 1.20.120.380 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Type 1-topoisomerase catalytic fragment, domain 2 | 0.54 | 38.0 | 4.24e-01 | 86.0% | 95.7% |
| 1n81A00 | 1.10.3030.10 | Mainly Alpha › Orthogonal Bundle › Gametocyte protein Pfg27 › Gametocyte protein Pfg27 | 0.53 | 42.0 | 3.71e-01 | 86.0% | 87.1% |
| 3r6nB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 37.0 | 3.09e-01 | 71.9% | 73.2% |
| 6xpdA01 | 1.20.1510.10 | Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain | 0.52 | 44.0 | 3.85e-01 | 97.5% | 93.1% |
| 7dswA01 | 1.20.1530.20 | Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › | 0.51 | 45.0 | 3.17e-01 | 100.0% | 58.5% |
| 8sbeA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.50 | 43.0 | 3.70e-01 | 94.2% | 68.9% |
ECOD (30)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| None | — | 1.00 | 98.0 | 6.33e-01 | 100.0% | 28.1% | |
| 4622106 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.99 | 96.0 | 6.23e-01 | 100.0% | 27.8% |
| 4031025 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.96 | 92.0 | 5.93e-01 | 99.2% | 27.2% |
| 3385846 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.92 | 88.0 | 5.71e-01 | 100.0% | 27.4% |
| 5077964 | 3355.1.1.41 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › DUF401 | 0.82 | 71.0 | 4.88e-01 | 100.0% | 30.0% |
| 4582471 | 3355.1.1.11 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › GntP_permease | 0.81 | 75.0 | 5.03e-01 | 100.0% | 28.5% |
| 3591004 | 3355.1.1.8 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_H_antiporter | 0.81 | 75.0 | 4.96e-01 | 100.0% | 26.9% |
| 4949155 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.79 | 73.0 | 5.08e-01 | 100.0% | 89.5% |
| 4140252 | 3355.1.1.8 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_H_antiporter | 0.79 | 72.0 | 4.89e-01 | 100.0% | 29.4% |
| 3944432 | 3355.1.1.0 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter | 0.76 | 69.0 | 4.62e-01 | 100.0% | 27.9% |
| 5016672 | 3355.1.1.8 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › Na_H_antiporter | 0.74 | 68.0 | 4.67e-01 | 100.0% | 33.8% |
| 5083410 | 3355.1.1.0 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter | 0.73 | 66.0 | 4.63e-01 | 100.0% | 67.4% |
| 3382566 | 5069.1.1.4 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Ferric_reduct | 0.63 | 40.0 | 3.27e-01 | 93.4% | 34.5% |
| 5011074 | 1111.1.1.8 ↗ | alpha complex topology › Trimeric intracellular cation (TRIC) channel › Trimeric intracellular cation (TRIC) channel › Trimeric intracellular cation (TRIC) channel › DUF2070 | 0.62 | 52.0 | 4.74e-01 | 94.2% | 83.9% |
| 4656331 | 611.1.1.0 ↗ | alpha bundles › N-cbl like › Transferrin receptor ectodomain, C-terminal domain › Transferrin receptor ectodomain, C-terminal domain | 0.60 | 42.0 | 3.82e-01 | 71.9% | 95.6% |
| 4405286 | 604.39.1.12 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › VTT_dom | 0.59 | 49.0 | 4.19e-01 | 92.6% | 60.0% |
| 5016694 | 7064.1.1.1 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 | 0.59 | 45.0 | 4.25e-01 | 82.6% | 69.3% |
| 3939145 | 5001.1.1.32 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Solute_trans_a | 0.58 | 46.0 | 3.54e-01 | 87.6% | 67.3% |
| 3192242 | 604.39.1.0 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters | 0.57 | 50.0 | 4.42e-01 | 95.0% | 82.9% |
| 4147943 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.56 | 45.0 | 4.30e-01 | 87.6% | 97.2% |
| 3287431 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.54 | 38.0 | 3.23e-01 | 72.7% | 83.9% |
| 4445149 | 174.1.1.21 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF2417 | 0.53 | 38.0 | 3.25e-01 | 72.7% | 46.2% |
| 3353167 | 3343.1.1.2 ↗ | alpha complex topology › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › GCP_C_terminal,GCP_N_terminal | 0.53 | 41.0 | 2.65e-01 | 84.3% | 19.7% |
| 4019175 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.52 | 37.0 | 3.06e-01 | 72.7% | 79.1% |
| 3250022 | 5045.1.1.1 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A | 0.51 | 44.0 | 3.61e-01 | 98.3% | 87.3% |
| 4945388 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.51 | 40.0 | 3.42e-01 | 82.6% | 92.0% |
| 3391684 | 3883.1.1.11 ↗ | alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf, PF29417 | 0.51 | 44.0 | 3.46e-01 | 95.9% | 65.9% |
| 2322275 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.51 | 42.0 | 3.93e-01 | 91.7% | 77.4% |
| 4055968 | 1075.5.1.8 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 | 0.50 | 40.0 | 3.42e-01 | 86.0% | 72.5% |
| 3275929 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.50 | 36.0 | 3.52e-01 | 73.6% | 76.2% |
D3
medium
residues 1-57
Domain cluster:
representative
CATH (10)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1ufhA00 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.76 | 56.0 | 4.06e-01 | 80.7% | 29.0% |
| 3h36A00 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.74 | 55.0 | 4.97e-01 | 80.7% | 62.8% |
| 3c24A02 | 1.10.3640.10 | Mainly Alpha › Orthogonal Bundle › putative oxidoreductase fold › Semialdehyde dehydrogenase-like, C-terminal | 0.73 | 54.0 | 4.50e-01 | 94.7% | 46.0% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.72 | 54.0 | 4.71e-01 | 91.2% | 54.1% |
| 1cf7B00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.69 | 55.0 | 4.93e-01 | 89.5% | 72.0% |
| 3qxzA02 | 1.10.12.10 | Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 | 0.67 | 49.0 | 4.92e-01 | 86.0% | 78.3% |
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.66 | 45.0 | 4.12e-01 | 70.2% | 59.5% |
| 1uxtA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.63 | 45.0 | 2.96e-01 | 78.9% | 36.3% |
| 4bpxD00 | 1.20.930.80 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › | 0.56 | 46.0 | 3.21e-01 | 94.7% | 77.5% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 45.0 | 3.79e-01 | 100.0% | 86.0% |
ECOD (5)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3923696 | 198.1.1.0 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like | 0.81 | 59.0 | 5.01e-01 | 78.9% | 48.9% |
| 4216505 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.76 | 61.0 | 3.90e-01 | 87.7% | 19.2% |
| 3552352 | 198.1.1.0 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like | 0.72 | 53.0 | 4.67e-01 | 78.9% | 54.1% |
| 4027517 | 109.3.1.165 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank, Ank_2, Ank_3, Ank_4, Ank_5 | 0.68 | 60.0 | 3.66e-01 | 100.0% | 30.4% |
| 5032368 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.55 | 48.0 | 4.62e-01 | 100.0% | 90.8% |
D4
medium
residues 58-91_234-315
Domain cluster:
representative
CATH (34)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3o6xA02 | 1.20.120.1560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.69 | 48.0 | 4.46e-01 | 72.4% | 85.8% |
| 1r0dA00 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.65 | 45.0 | 3.80e-01 | 71.6% | 63.2% |
| 1dkxA02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.64 | 43.0 | 4.97e-01 | 75.0% | 100.0% |
| 2ot4A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.62 | 44.0 | 4.56e-01 | 72.4% | 92.5% |
| 3g9gA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.62 | 38.0 | 2.90e-01 | 95.7% | 28.0% |
| 3djbA01 | 1.10.472.50 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › HD-domain/PDEase-like | 0.61 | 43.0 | 4.66e-01 | 75.0% | 88.5% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.60 | 37.0 | 3.88e-01 | 99.1% | 67.9% |
| 7dswA01 | 1.20.1530.20 | Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › | 0.58 | 51.0 | 3.54e-01 | 98.3% | 64.9% |
| 4rflA02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.57 | 44.0 | 3.80e-01 | 85.3% | 78.9% |
| 8sbeA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.57 | 41.0 | 3.51e-01 | 75.0% | 92.5% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.56 | 45.0 | 4.15e-01 | 88.8% | 86.9% |
| 2k3nA00 | 1.10.274.60 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain | 0.55 | 40.0 | 3.65e-01 | 75.9% | 63.1% |
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.55 | 36.0 | 3.82e-01 | 94.8% | 72.9% |
| 7kypB01 | 1.10.3470.10 | Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC | 0.55 | 47.0 | 3.60e-01 | 94.8% | 84.5% |
| 4zvaA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.54 | 44.0 | 4.14e-01 | 91.4% | 76.5% |
| 4gnkE00 | 1.20.1230.10 | Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain | 0.54 | 37.0 | 2.95e-01 | 99.1% | 34.9% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.53 | 39.0 | 3.90e-01 | 75.9% | 88.3% |
| 7uzqK01 | 1.10.3430.10 | Mainly Alpha › Orthogonal Bundle › Ammonium transporter fold › Ammonium transporter AmtB like domains | 0.53 | 41.0 | 2.99e-01 | 83.6% | 48.1% |
| 6v9zA02 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.53 | 38.0 | 2.82e-01 | 75.0% | 77.5% |
| 4ioeA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.53 | 35.0 | 3.96e-01 | 100.0% | 90.8% |
| 3ihuA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.52 | 43.0 | 4.12e-01 | 90.5% | 99.3% |
| 2gscC00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.52 | 37.0 | 3.82e-01 | 73.3% | 82.7% |
| 4gc0A02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.52 | 40.0 | 3.31e-01 | 83.6% | 69.5% |
| 3pltA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.52 | 35.0 | 2.90e-01 | 100.0% | 37.4% |
| 1b04A03 | 1.10.287.610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.52 | 26.0 | 3.37e-01 | 78.4% | 88.7% |
| 7w5gA01 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.51 | 38.0 | 2.77e-01 | 79.3% | 76.1% |
| 3cr3A00 | 1.25.40.340 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › DhaL domain | 0.51 | 40.0 | 3.46e-01 | 85.3% | 100.0% |
| 2ic6A00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 31.0 | 3.86e-01 | 94.8% | 100.0% |
| 1tjoB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.51 | 38.0 | 3.36e-01 | 77.6% | 60.0% |
| 1quuA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 35.0 | 3.44e-01 | 70.7% | 84.9% |
| 3wmeA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.51 | 38.0 | 2.86e-01 | 80.2% | 50.8% |
| 2ycdA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.51 | 35.0 | 3.49e-01 | 85.3% | 68.4% |
| 1h7cA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 34.0 | 3.60e-01 | 100.0% | 77.7% |
| 7aalA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.50 | 34.0 | 2.65e-01 | 100.0% | 29.7% |
ECOD (38)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4622106 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.99 | 97.0 | 6.19e-01 | 100.0% | 61.1% |
| 3385846 | 3355.1.1.2 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › CitMHS | 0.97 | 94.0 | 5.99e-01 | 100.0% | 57.3% |
| 3583324 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.70 | 44.0 | 3.95e-01 | 100.0% | 46.5% |
| 5082667 | 633.6.1.1 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 | 0.65 | 50.0 | 4.73e-01 | 79.3% | 83.0% |
| 4365553 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.63 | 43.0 | 4.80e-01 | 72.4% | 90.0% |
| 4380113 | 632.15.1.4 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) › HSP70 | 0.62 | 44.0 | 4.54e-01 | 73.3% | 80.9% |
| 5035275 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.62 | 43.0 | 4.55e-01 | 72.4% | 92.4% |
| 4318044 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.62 | 42.0 | 4.63e-01 | 70.7% | 90.0% |
| 4564470 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.62 | 44.0 | 4.67e-01 | 73.3% | 89.0% |
| 4469387 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.61 | 43.0 | 4.28e-01 | 72.4% | 70.8% |
| 4972007 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.61 | 46.0 | 4.30e-01 | 79.3% | 82.9% |
| 2833540 | 628.1.1.1 ↗ | alpha bundles › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › FCD | 0.60 | 45.0 | 4.12e-01 | 77.6% | 91.2% |
| 3449442 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.58 | 41.0 | 4.25e-01 | 72.4% | 95.2% |
| 3972329 | 633.5.1.0 ↗ | alpha bundles › Bromodomain-like › LemA-like › LemA-like | 0.57 | 44.0 | 3.98e-01 | 82.8% | 63.0% |
| 4024699 | 3871.1.1.1 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN | 0.57 | 39.0 | 3.65e-01 | 70.7% | 95.9% |
| 3309382 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.56 | 41.0 | 3.05e-01 | 76.7% | 69.4% |
| 4980098 | 3834.1.1.0 ↗ | alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain | 0.56 | 34.0 | 2.61e-01 | 81.0% | 26.4% |
| 3932987 | 4177.1.1.10 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › GMIP-like_FCH | 0.56 | 38.0 | 2.96e-01 | 70.7% | 80.4% |
| 4565029 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.55 | 42.0 | 3.54e-01 | 81.9% | 81.9% |
| 3495915 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.55 | 36.0 | 2.82e-01 | 99.1% | 30.0% |
| 3264196 | 5067.1.1.13 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ALMT | 0.54 | 47.0 | 4.24e-01 | 96.6% | 68.5% |
| 3934670 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.54 | 46.0 | 4.04e-01 | 93.1% | 78.3% |
| 3973071 | 633.6.1.0 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like | 0.54 | 42.0 | 3.85e-01 | 81.9% | 80.0% |
| 3401364 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.54 | 48.0 | 4.63e-01 | 98.3% | 96.2% |
| 4977940 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.53 | 40.0 | 3.46e-01 | 81.9% | 88.0% |
| 4024597 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.53 | 42.0 | 3.87e-01 | 84.5% | 82.7% |
| 3894393 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.53 | 45.0 | 4.16e-01 | 94.8% | 92.7% |
| 3596926 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.53 | 42.0 | 3.30e-01 | 87.1% | 86.0% |
| 4973347 | 515.1.1.4 ↗ | alpha arrays › Transcription factor STAT-4 N-domain › Transcription factor STAT-4 N-domain › Transcription factor STAT-4 N-domain › EMC3_TMCO1 | 0.53 | 32.0 | 2.85e-01 | 95.7% | 40.6% |
| 3335074 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.52 | 38.0 | 3.75e-01 | 78.4% | 99.2% |
| 3950765 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.52 | 35.0 | 2.51e-01 | 100.0% | 22.9% |
| 5023920 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.52 | 40.0 | 3.79e-01 | 83.6% | 91.0% |
| 3392594 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.52 | 35.0 | 3.66e-01 | 98.3% | 72.7% |
| 3484031 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.52 | 36.0 | 3.47e-01 | 72.4% | 80.7% |
| 4556484 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.51 | 35.0 | 3.49e-01 | 94.8% | 66.4% |
| 3576467 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.51 | 35.0 | 2.61e-01 | 100.0% | 26.6% |
| 3755118 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.51 | 35.0 | 3.51e-01 | 99.1% | 69.6% |
| 3790837 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.50 | 35.0 | 3.39e-01 | 73.3% | 77.0% |