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CAKLQF020000027.1__CAH1093043.1__SAMEA5780031_03638__00059

Bact-Vir

CAKLQF020000027.1__CAH1093043.1__SAMEA5780031_03638__00059

Identity

Kingdom:
phage

Quality

86.0 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 7-69
PDB
Domain cluster: representative
CATH (60)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5svlA01 1.10.287.940 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › atp-gated p2x4 ion channel 0.86 65.0 6.40e-01 81.0% 91.2%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.85 79.0 6.30e-01 100.0% 54.7%
5uh5D02 1.10.132.30 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › RNA polymerase Rpb1 funnel domain 0.84 69.0 5.20e-01 90.5% 39.9%
7dluA01 1.10.287.1260 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.82 68.0 5.72e-01 90.5% 62.9%
2x2vA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.82 68.0 6.59e-01 87.3% 91.2%
3fbzA01 1.20.58.800 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.82 60.0 5.05e-01 77.8% 48.0%
2o5iN07 1.10.132.30 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › RNA polymerase Rpb1 funnel domain 0.81 72.0 5.75e-01 95.2% 63.8%
2e9fB01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.80 56.0 4.78e-01 76.2% 47.9%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.79 71.0 5.89e-01 100.0% 58.7%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.78 58.0 4.90e-01 82.5% 49.0%
3gi7A00 1.20.1270.180 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.76 62.0 5.35e-01 92.1% 62.1%
2d2sA02 1.20.58.1220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, C-terminal helical domain 0.76 62.0 5.34e-01 90.5% 60.4%
6ynwH01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.76 67.0 6.34e-01 100.0% 83.8%
3fd0A01 3.90.1150.60 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Methioning gamme-lyase, C-terminal domain 0.75 67.0 4.72e-01 100.0% 38.9%
6qumQ00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.75 59.0 5.67e-01 87.3% 97.3%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.74 54.0 4.55e-01 76.2% 52.9%
5dn6J00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.74 59.0 5.67e-01 88.9% 77.0%
1wcrA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.73 56.0 4.69e-01 82.5% 49.5%
3b0cW00 1.10.20.10 Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A 0.73 53.0 5.09e-01 85.7% 67.1%
2yf4F00 1.10.3420.10 Mainly Alpha › Orthogonal Bundle › putative ntp pyrophosphohydrolase like fold › putative ntp pyrophosphohydrolase like domain 0.72 57.0 4.30e-01 87.3% 37.1%
6p73A02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.72 56.0 4.31e-01 84.1% 50.3%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.72 58.0 4.70e-01 87.3% 96.6%
5b1oA00 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.71 53.0 5.33e-01 87.3% 78.5%
2k0nA00 1.10.246.20 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Coactivator CBP, KIX domain 0.70 54.0 4.99e-01 92.1% 63.5%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.70 57.0 4.69e-01 90.5% 96.5%
2mpnA00 6.10.140.1340 Special › Helix non-globular › Helix Hairpins › 0.70 54.0 5.36e-01 85.7% 86.8%
2c5iT00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 52.0 4.55e-01 82.5% 53.2%
2yn7A00 1.10.3160.10 Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 0.69 61.0 4.24e-01 100.0% 80.8%
2d9dA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.69 49.0 4.38e-01 74.6% 53.9%
3qnmA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.69 50.0 4.48e-01 77.8% 54.4%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.69 61.0 5.54e-01 100.0% 77.6%
3fd9A03 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.68 51.0 4.87e-01 81.0% 68.5%
4hiaA00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.68 52.0 3.79e-01 84.1% 29.5%
1vw4T01 6.10.330.20 Special › Helix non-globular › Monooxygenase › 0.68 54.0 4.41e-01 85.7% 63.4%
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.68 48.0 4.67e-01 79.4% 66.2%
2yx8A00 1.10.150.510 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Receptor activity modifying family 0.66 53.0 4.90e-01 88.9% 69.1%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.66 51.0 4.70e-01 82.5% 70.4%
1nt2B02 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.66 52.0 5.16e-01 87.3% 80.6%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 50.0 4.31e-01 82.5% 52.0%
1t7lB01 3.20.20.210 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › 0.66 58.0 3.52e-01 96.8% 92.6%
1ku9A02 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.65 50.0 5.00e-01 81.0% 93.8%
4iw9A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.65 55.0 4.54e-01 93.7% 60.2%
3l1nA01 6.10.140.790 Special › Helix non-globular › Helix Hairpins › 0.65 49.0 5.40e-01 81.0% 100.0%
5k2xA00 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.65 52.0 3.19e-01 92.1% 88.4%
3onjA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.64 57.0 4.96e-01 100.0% 67.0%
2bdeA03 1.20.58.1160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 49.0 4.65e-01 88.9% 68.8%
2oerA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.62 49.0 3.65e-01 92.1% 61.5%
6a3kA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.60 49.0 3.93e-01 90.5% 50.4%
4ielA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.60 42.0 3.55e-01 76.2% 50.0%
3wd6A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.60 47.0 3.83e-01 87.3% 45.8%
4bpxD00 1.20.930.80 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › 0.60 47.0 3.35e-01 90.5% 51.6%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 53.0 4.14e-01 100.0% 47.7%
1yg2A02 6.10.140.190 Special › Helix non-globular › Helix Hairpins › 0.59 50.0 4.46e-01 93.7% 77.8%
1urfA00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.59 51.0 4.72e-01 98.4% 98.8%
1bhaA00 1.10.287.170 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.58 51.0 5.03e-01 95.2% 91.0%
2gsqA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.58 48.0 4.02e-01 90.5% 55.6%
4nb5B02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.58 51.0 5.13e-01 100.0% 100.0%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.58 47.0 4.45e-01 92.1% 84.4%
6t0bc01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.57 49.0 4.59e-01 100.0% 80.8%
2kw6A00 6.10.140.1300 Special › Helix non-globular › Helix Hairpins › 0.52 42.0 4.15e-01 95.2% 83.1%
ECOD (63)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4076608 109.4.1.924 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_CcmH_CycH 0.96 82.0 5.06e-01 92.1% 19.0%
3988447 5043.1.1.0 extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like 0.92 77.0 8.18e-01 87.3% 100.0%
5039692 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.90 81.0 6.96e-01 96.8% 65.3%
5066143 5041.1.1.0 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C 0.90 78.0 7.28e-01 92.1% 77.3%
3691750 376.1.1.8 few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › U-box 0.89 81.0 5.97e-01 100.0% 40.9%
None 0.89 75.0 4.75e-01 93.7% 20.4%
3720672 109.4.1.1591 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › U-box 0.88 81.0 5.11e-01 100.0% 22.1%
5043880 605.4.1.0 alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein 0.87 73.0 6.58e-01 92.1% 67.1%
4959036 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.87 78.0 6.44e-01 96.8% 61.9%
4346136 605.1.1.108 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › GrpE 0.84 71.0 7.03e-01 95.2% 87.7%
3742303 310.2.1.1 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF 0.84 78.0 5.34e-01 100.0% 33.0%
3208712 5043.1.1.9 extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like › Rrn7_cyclin_N 0.83 62.0 6.25e-01 79.4% 78.1%
4971237 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.83 75.0 6.16e-01 98.4% 58.2%
None 0.82 68.0 4.67e-01 88.9% 27.8%
5043291 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.82 64.0 5.87e-01 85.7% 65.0%
5055969 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.82 72.0 6.29e-01 98.4% 67.4%
3798302 103.4.1.0 alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein 0.82 64.0 6.22e-01 84.1% 75.7%
3988424 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.80 71.0 7.07e-01 100.0% 93.8%
4996722 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.80 69.0 6.04e-01 96.8% 66.3%
4024271 3871.1.1.1 alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN 0.80 72.0 5.57e-01 100.0% 47.4%
4937236 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.80 71.0 6.06e-01 98.4% 66.0%
3967002 3843.1.1.27 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › COX4_pro 0.79 70.0 6.28e-01 98.4% 71.8%
4333013 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.79 65.0 5.95e-01 88.9% 72.5%
3882597 4009.1.1.0 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.79 66.0 5.83e-01 92.1% 64.4%
4008053 4168.1.1.7 alpha duplicates or obligate multimers › HAMP domain › HAMP domain › HAMP domain › PF26769 0.78 60.0 4.39e-01 82.5% 32.1%
4005270 3718.1.1.15 alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT › COX4_pro 0.78 67.0 5.80e-01 95.2% 68.4%
4149728 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.78 65.0 6.04e-01 92.1% 75.0%
5040955 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.78 64.0 5.37e-01 90.5% 62.9%
4620052 2004.1.1.5 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.77 71.0 4.33e-01 100.0% 20.0%
4358519 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.77 65.0 5.55e-01 92.1% 60.0%
4309485 4229.1.1.2 alpha bundles › Indolic compounds 2,3-dioxygenase-like › Indolic compounds 2,3-dioxygenase-like › Indolic compounds 2,3-dioxygenase-like › Trp_dioxygenase 0.77 68.0 4.23e-01 100.0% 18.3%
4641055 2004.1.1.6 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran,oligo_HPY 0.77 70.0 4.21e-01 100.0% 18.7%
4998576 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.77 64.0 6.13e-01 95.2% 80.0%
3589830 5043.2.1.8 extended segments › Sensor proteins transmembrane domains › NarQ transmembrane domain › NarQ transmembrane domain › DUF5592 0.76 64.0 6.22e-01 92.1% 82.9%
3347379 3470.1.1.26 extended segments › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain › DUF543 0.76 62.0 6.19e-01 90.5% 100.0%
3735607 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.76 59.0 5.43e-01 82.5% 66.3%
3514607 3226.1.1.3 alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › HCO3_cotransp 0.75 56.0 3.58e-01 88.9% 16.5%
3928795 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.75 58.0 4.99e-01 82.5% 58.9%
3578491 7023.1.1.0 alpha bundles › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein 0.75 61.0 5.62e-01 88.9% 71.2%
5028558 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.75 66.0 5.66e-01 100.0% 63.0%
4554416 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.74 62.0 5.52e-01 93.7% 67.8%
3904347 6026.1.1.0 alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain 0.74 54.0 5.18e-01 82.5% 66.7%
3725506 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.73 57.0 4.66e-01 82.5% 48.2%
5014387 3826.1.1.100 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › DUF2304 0.73 63.0 5.68e-01 95.2% 77.6%
3953860 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.73 63.0 5.94e-01 93.7% 80.0%
3697800 3559.1.1.0 a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 0.73 57.0 4.55e-01 82.5% 46.1%
3739839 5063.1.1.0 alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK 0.72 65.0 5.39e-01 100.0% 70.9%
3289545 150.8.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE 0.71 58.0 4.09e-01 88.9% 85.3%
5017842 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.70 58.0 5.31e-01 93.7% 81.2%
5075035 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.70 53.0 3.44e-01 82.5% 18.5%
4452302 605.1.1.162 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › COX4_pro 0.69 60.0 5.23e-01 95.2% 65.3%
4942387 632.7.1.66 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › DUF2304 0.69 59.0 4.93e-01 96.8% 57.3%
3643105 6026.1.1.1 alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain › cwf21 0.68 60.0 4.53e-01 100.0% 63.2%
5043641 205.1.1.16 a+b two layers › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › Fer4_7 0.67 53.0 3.75e-01 87.3% 59.5%
3933864 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.65 59.0 4.24e-01 100.0% 68.9%
4869741 3226.1.1.3 alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › HCO3_cotransp 0.65 57.0 3.55e-01 100.0% 18.6%
3283686 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.64 49.0 4.75e-01 82.5% 75.7%
4221666 3826.1.1.0 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) 0.63 49.0 4.34e-01 87.3% 78.9%
4522608 3812.1.1.15 alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE › COX4_pro 0.62 53.0 4.74e-01 96.8% 66.7%
4384067 632.7.1.37 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › LETM1_RBD 0.62 52.0 4.37e-01 95.2% 60.0%
4106620 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.60 53.0 5.03e-01 100.0% 93.3%
3772265 150.1.1.100 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › TMD0_ABC 0.60 50.0 3.86e-01 100.0% 79.4%
4459223 605.1.1.162 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › COX4_pro 0.54 47.0 4.20e-01 98.4% 71.0%
D2 high residues 85-226
PDB
Domain cluster: representative
CATH (39)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2d2sA01 1.20.58.1210 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain 0.78 49.0 5.41e-01 95.8% 77.6%
4cqiA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 37.0 4.24e-01 98.6% 66.4%
2i0mA02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.67 41.0 4.68e-01 82.4% 84.2%
1orsC00 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.66 39.0 4.04e-01 82.4% 60.6%
2odvA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 43.0 4.78e-01 81.0% 83.0%
2hz8A00 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.66 39.0 4.25e-01 82.4% 70.4%
3vkgA02 1.20.140.100 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain 0.66 34.0 3.43e-01 77.5% 47.6%
2fupA00 1.20.58.300 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like 0.66 47.0 4.99e-01 80.3% 83.5%
2qupA00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.65 37.0 4.00e-01 82.4% 64.7%
3nowA02 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.65 37.0 2.65e-01 100.0% 18.5%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.65 38.0 4.15e-01 81.0% 69.2%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.64 38.0 3.94e-01 81.0% 62.3%
2fbnA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.63 40.0 3.98e-01 97.9% 59.5%
4epzA00 1.25.40.810 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › UpxZ 0.63 37.0 3.59e-01 100.0% 51.3%
2wzkA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.63 40.0 4.47e-01 96.5% 81.8%
1h6gA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.63 36.0 3.88e-01 81.0% 64.5%
3eupB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.62 44.0 3.92e-01 71.8% 87.5%
1w99A01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.61 51.0 4.76e-01 100.0% 72.8%
3nnrA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.59 49.0 4.36e-01 88.0% 87.6%
1st6A04 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.59 35.0 3.83e-01 81.0% 70.1%
1e91A00 1.20.1160.11 Mainly Alpha › Up-down Bundle › Paired amphipathic helix 2 (pah2 repeat) › Paired amphipathic helix 0.59 29.0 3.57e-01 95.1% 74.1%
4hyjA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.59 54.0 4.55e-01 100.0% 83.5%
6h2dS01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.58 46.0 3.91e-01 82.4% 73.5%
3anwB00 1.20.58.2050 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 40.0 3.86e-01 85.2% 61.7%
1jogA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.58 38.0 3.94e-01 92.3% 69.6%
3mvpA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.57 40.0 3.96e-01 71.1% 100.0%
6nplA01 1.20.1740.10 Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I 0.57 46.0 3.19e-01 84.5% 67.0%
2xpzA04 1.25.40.320 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal domain 0.56 33.0 3.17e-01 99.3% 47.9%
6fhpD00 1.10.390.10 Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2 0.56 25.0 3.50e-01 88.0% 90.3%
7wujE01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.55 45.0 3.75e-01 88.0% 79.0%
2e87A01 1.20.120.1190 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.55 39.0 3.77e-01 80.3% 65.0%
3mfnB00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.55 35.0 3.72e-01 79.6% 72.2%
2pm6A00 1.25.40.1030 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.54 39.0 2.93e-01 100.0% 30.7%
2a2fX02 1.20.58.670 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D 0.53 37.0 3.85e-01 95.8% 77.5%
8iprA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.53 45.0 3.60e-01 96.5% 92.9%
7f16R01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.51 43.0 3.48e-01 90.8% 80.1%
3swhA01 1.10.357.50 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.51 44.0 4.19e-01 99.3% 80.6%
2h7oA01 1.20.120.1330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Rac1-binding domain, N-terminal GTPase binding subdomain 0.50 37.0 3.94e-01 97.9% 88.6%
5h5mA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.50 33.0 3.50e-01 79.6% 73.1%
ECOD (36)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3174200 109.4.1.356 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.76 49.0 3.60e-01 97.9% 26.3%
3714307 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.72 50.0 4.79e-01 100.0% 61.9%
3365690 109.4.1.927 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_LIN 0.72 45.0 3.77e-01 84.5% 36.7%
3282266 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.71 40.0 4.57e-01 82.4% 74.3%
3167993 603.1.1.97 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE 0.70 65.0 5.59e-01 100.0% 77.3%
3578418 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.70 48.0 4.98e-01 83.8% 73.3%
3728184 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.70 51.0 4.28e-01 100.0% 45.5%
5056942 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.69 45.0 3.95e-01 83.1% 44.9%
3496810 5069.1.1.41 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Rost 0.67 46.0 3.96e-01 84.5% 44.9%
3382799 109.4.1.330 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BIG2_C 0.65 55.0 4.37e-01 100.0% 46.1%
3249439 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.65 44.0 4.27e-01 83.1% 61.9%
3252200 603.1.1.6 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin_2 0.64 59.0 5.70e-01 100.0% 91.3%
3693144 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 50.0 4.67e-01 95.8% 65.6%
3623280 603.1.1.110 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF26585 0.64 60.0 5.33e-01 100.0% 83.6%
4020876 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 50.0 4.43e-01 97.2% 61.0%
3368223 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.60 55.0 4.79e-01 100.0% 76.3%
3768531 109.4.1.1705 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF26106 0.59 46.0 4.10e-01 97.9% 57.6%
3934805 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 47.0 4.27e-01 97.2% 63.6%
4025012 633.7.1.0 alpha bundles › Bromodomain-like › Bacillus cereus metalloprotein-like › Bacillus cereus metalloprotein-like 0.57 42.0 3.98e-01 100.0% 63.4%
3261521 109.4.1.167 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Rif1_N 0.57 52.0 3.87e-01 99.3% 42.6%
3929364 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.56 43.0 4.57e-01 94.4% 89.6%
3872311 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.55 38.0 3.51e-01 78.9% 54.1%
3969975 3758.2.1.0 alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB 0.55 43.0 3.74e-01 82.4% 82.8%
3495508 109.6.1.0 alpha superhelices › Repetitive alpha hairpins › Ras GEF › Ras GEF 0.55 49.0 3.35e-01 97.9% 28.2%
3386017 3758.2.1.1 alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB 0.55 43.0 3.75e-01 82.4% 78.9%
3175638 5051.1.1.2 alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › AA_permease 0.55 44.0 3.03e-01 84.5% 59.2%
5014336 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.53 37.0 3.69e-01 78.2% 68.3%
5010860 1075.1.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.52 34.0 2.95e-01 78.9% 40.9%
3682653 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 47.0 3.06e-01 100.0% 43.4%
3742628 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.52 38.0 3.73e-01 74.6% 89.6%
3176505 109.4.1.1307 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps52_CC, Vps52_C 0.52 48.0 3.34e-01 100.0% 35.5%
3588738 150.5.1.83 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › DUF3899 0.51 36.0 4.01e-01 78.9% 92.7%
4962491 109.3.1.490 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › PF26790 0.51 43.0 3.96e-01 100.0% 69.7%
3996346 601.1.1.3 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › PDC10_C 0.51 40.0 3.94e-01 100.0% 78.0%
3939091 601.3.1.18 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Las1 0.51 38.0 3.73e-01 92.3% 70.6%
3560403 5048.1.1.1 alpha complex topology › Aquaporin-like › Aquaporin-like › Aquaporin-like › MIP 0.51 46.0 3.77e-01 100.0% 77.3%