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CAKLQF020000029.1__CAH1093683.1__SAMEA5780031_03724__00017
Bact-VirCAKLQF020000029.1__CAH1093683.1__SAMEA5780031_03724__00017
Identity
- Kingdom:
- phage
Quality
87.9
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 51-166
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06772.17 best | LtrA | 139.5 | 2.30e-40 | 100.0% | 31.3% |
CATH (71)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2v0oB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.81 | 60.0 | 4.50e-01 | 77.6% | 75.6% |
| 4al0A00 | 1.20.120.550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain | 0.79 | 73.0 | 6.71e-01 | 100.0% | 91.8% |
| 2efkA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.77 | 53.0 | 4.04e-01 | 70.7% | 80.5% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.77 | 53.0 | 5.38e-01 | 71.6% | 81.2% |
| 1k04A02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.76 | 54.0 | 5.70e-01 | 74.1% | 97.1% |
| 3ay5A02 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.76 | 67.0 | 6.00e-01 | 98.3% | 77.6% |
| 4jioA01 | 1.20.120.560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain | 0.75 | 56.0 | 5.00e-01 | 77.6% | 91.9% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.75 | 55.0 | 5.40e-01 | 75.9% | 82.0% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.74 | 52.0 | 5.00e-01 | 72.4% | 83.1% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.74 | 52.0 | 5.01e-01 | 73.3% | 66.9% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.73 | 54.0 | 5.43e-01 | 76.7% | 81.4% |
| 3qweA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.73 | 53.0 | 4.04e-01 | 75.0% | 83.8% |
| 3pltA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.73 | 55.0 | 4.43e-01 | 78.4% | 78.0% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.73 | 51.0 | 4.98e-01 | 73.3% | 75.4% |
| 1q0gA00 | 1.20.120.400 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase | 0.73 | 51.0 | 5.13e-01 | 75.9% | 71.8% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.72 | 49.0 | 5.00e-01 | 71.6% | 70.8% |
| 3ddlA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.72 | 51.0 | 3.96e-01 | 73.3% | 65.1% |
| 2ot4A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.72 | 53.0 | 5.56e-01 | 77.6% | 92.5% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.72 | 50.0 | 5.01e-01 | 72.4% | 71.7% |
| 1wdzA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.71 | 50.0 | 3.99e-01 | 72.4% | 81.4% |
| 3zsuA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.70 | 48.0 | 4.86e-01 | 73.3% | 69.5% |
| 3s84A02 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.70 | 52.0 | 4.76e-01 | 78.4% | 84.7% |
| 4e40A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.70 | 50.0 | 3.94e-01 | 74.1% | 82.4% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.70 | 49.0 | 4.92e-01 | 71.6% | 80.2% |
| 2y44A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.70 | 51.0 | 4.40e-01 | 76.7% | 90.8% |
| 3i9wA00 | 1.20.58.920 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 50.0 | 3.76e-01 | 73.3% | 89.3% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.69 | 49.0 | 4.75e-01 | 72.4% | 75.0% |
| 2okuA00 | 1.20.120.470 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Acyl-CoA dehydrogenase, C-terminal domain | 0.69 | 62.0 | 6.13e-01 | 100.0% | 93.4% |
| 3rfyA02 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.68 | 48.0 | 5.00e-01 | 72.4% | 78.5% |
| 4p9tA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.68 | 49.0 | 4.93e-01 | 75.9% | 79.2% |
| 3ls1A00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.68 | 47.0 | 4.53e-01 | 72.4% | 62.4% |
| 4hyjA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.68 | 50.0 | 3.93e-01 | 76.7% | 94.1% |
| 1oahA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.67 | 53.0 | 4.96e-01 | 84.5% | 84.5% |
| 4wpeA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.66 | 48.0 | 3.69e-01 | 75.9% | 82.9% |
| 2q12A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.66 | 49.0 | 3.90e-01 | 77.6% | 80.6% |
| 4o6yB00 | 1.20.120.1770 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.66 | 48.0 | 3.96e-01 | 75.9% | 52.1% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.66 | 47.0 | 4.78e-01 | 73.3% | 76.3% |
| 4jvsA01 | 1.20.120.1700 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.66 | 47.0 | 4.58e-01 | 73.3% | 73.8% |
| 1xzpA02 | 1.20.120.430 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 | 0.66 | 45.0 | 4.01e-01 | 70.7% | 58.4% |
| 7xk2R01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.65 | 48.0 | 3.66e-01 | 76.7% | 38.9% |
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.64 | 47.0 | 4.08e-01 | 77.6% | 88.3% |
| 2wb7A03 | 1.20.120.870 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain | 0.64 | 56.0 | 5.32e-01 | 97.4% | 82.4% |
| 4kc9A02 | 1.20.120.1750 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.64 | 57.0 | 4.66e-01 | 100.0% | 60.2% |
| 6z74C02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.63 | 51.0 | 4.67e-01 | 100.0% | 65.4% |
| 2hz8A00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.62 | 43.0 | 4.38e-01 | 71.6% | 75.7% |
| 3kavA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.62 | 42.0 | 4.41e-01 | 71.6% | 78.4% |
| 4x28C03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.62 | 56.0 | 5.20e-01 | 100.0% | 97.9% |
| 3dytA02 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.61 | 45.0 | 3.87e-01 | 77.6% | 93.2% |
| 5af7B03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.61 | 54.0 | 5.04e-01 | 99.1% | 92.6% |
| 2x0cA01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.61 | 55.0 | 4.77e-01 | 99.1% | 86.0% |
| 2id6A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.61 | 44.0 | 3.97e-01 | 74.1% | 88.3% |
| 4od4A02 | 1.20.120.1780 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › UbiA prenyltransferase | 0.60 | 41.0 | 4.07e-01 | 73.3% | 66.4% |
| 4p9fA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.60 | 46.0 | 4.31e-01 | 95.7% | 65.3% |
| 3dyjA02 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.60 | 51.0 | 4.73e-01 | 94.0% | 90.1% |
| 3zciA00 | 1.20.58.1660 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 54.0 | 4.60e-01 | 100.0% | 92.1% |
| 2z1qB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.59 | 53.0 | 5.08e-01 | 100.0% | 99.3% |
| 2rfqC03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.59 | 53.0 | 4.63e-01 | 100.0% | 81.1% |
| 1xwmA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.58 | 51.0 | 4.10e-01 | 93.1% | 96.2% |
| 1hw1A02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.58 | 44.0 | 4.09e-01 | 97.4% | 62.3% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.58 | 51.0 | 4.69e-01 | 98.3% | 74.2% |
| 7yu4A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.57 | 46.0 | 3.52e-01 | 84.5% | 94.6% |
| 4hkrA00 | 1.20.140.140 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Calcium release-activated calcium channel protein Orai | 0.57 | 49.0 | 4.49e-01 | 100.0% | 86.1% |
| 1x8zB00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.56 | 50.0 | 4.60e-01 | 99.1% | 76.9% |
| 1aueB00 | 1.20.120.150 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › FKBP12-rapamycin binding domain | 0.56 | 42.0 | 4.69e-01 | 94.8% | 97.9% |
| 1rj1A00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.56 | 48.0 | 4.47e-01 | 95.7% | 83.1% |
| 6gy8A01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.56 | 50.0 | 3.58e-01 | 98.3% | 79.8% |
| 3frrA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.55 | 48.0 | 4.08e-01 | 100.0% | 58.6% |
| 1mijA00 | 1.10.10.500 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeo-prospero domain | 0.55 | 37.0 | 3.57e-01 | 94.8% | 58.3% |
| 3vkgA02 | 1.20.140.100 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain | 0.54 | 47.0 | 4.43e-01 | 98.3% | 93.9% |
| 5dqqA01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.54 | 37.0 | 3.61e-01 | 76.7% | 62.5% |
| 4yonA01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.50 | 44.0 | 3.64e-01 | 99.1% | 76.4% |
ECOD (76)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4980771 | 1174.1.1.2 ↗ | alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 › LtrA | 0.93 | 87.0 | 7.17e-01 | 100.0% | 60.5% |
| 4031155 | 1174.1.1.2 ↗ | alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 › LtrA | 0.92 | 87.0 | 7.25e-01 | 100.0% | 62.2% |
| 3723424 | 1174.1.1.2 ↗ | alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 › LtrA | 0.92 | 86.0 | 6.85e-01 | 100.0% | 55.1% |
| 4078984 | 1174.1.1.2 ↗ | alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 › LtrA | 0.91 | 85.0 | 7.17e-01 | 100.0% | 64.0% |
| 3728941 | 1174.1.1.2 ↗ | alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 › LtrA | 0.90 | 85.0 | 7.08e-01 | 100.0% | 65.4% |
| 3289384 | 1174.1.1.2 ↗ | alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 › LtrA | 0.90 | 85.0 | 7.24e-01 | 100.0% | 67.1% |
| 3282728 | 1174.1.1.2 ↗ | alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 › LtrA | 0.89 | 85.0 | 7.14e-01 | 100.0% | 65.0% |
| 5076786 | 1174.1.1.1 ↗ | alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 › TMEM175 | 0.86 | 81.0 | 6.69e-01 | 100.0% | 65.6% |
| 3170937 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.82 | 61.0 | 4.52e-01 | 76.7% | 82.5% |
| 3846684 | 1174.1.1.1 ↗ | alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 › TMEM175 | 0.80 | 74.0 | 5.80e-01 | 100.0% | 55.7% |
| 3365580 | 601.1.2.3 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › GCIP_C | 0.76 | 68.0 | 5.85e-01 | 97.4% | 75.8% |
| 3715011 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.75 | 53.0 | 4.35e-01 | 71.6% | 97.4% |
| 4999359 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.75 | 54.0 | 5.98e-01 | 74.1% | 96.7% |
| 4927171 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.75 | 51.0 | 5.74e-01 | 70.7% | 97.8% |
| 3836689 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.73 | 53.0 | 4.85e-01 | 75.0% | 65.3% |
| None | — | 0.73 | 64.0 | 5.74e-01 | 98.3% | 77.0% | |
| 3272619 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.72 | 51.0 | 5.11e-01 | 73.3% | 80.8% |
| 4045134 | 601.4.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › 4HB_MCP_1 | 0.72 | 52.0 | 5.07e-01 | 75.9% | 73.8% |
| 4102845 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.72 | 51.0 | 5.06e-01 | 73.3% | 70.8% |
| 3608743 | 1189.1.1.0 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor | 0.72 | 53.0 | 4.05e-01 | 77.6% | 81.1% |
| 2885637 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.71 | 64.0 | 4.89e-01 | 100.0% | 45.1% |
| 3273377 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.70 | 49.0 | 3.99e-01 | 71.6% | 72.1% |
| 3336494 | 611.7.1.2 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › MCAfunc | 0.70 | 63.0 | 5.81e-01 | 99.1% | 77.3% |
| 5038395 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.69 | 48.0 | 4.33e-01 | 70.7% | 59.4% |
| 3389454 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.69 | 49.0 | 4.92e-01 | 74.1% | 74.2% |
| 4212526 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.69 | 48.0 | 4.82e-01 | 72.4% | 99.2% |
| 3970945 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.69 | 47.0 | 4.80e-01 | 70.7% | 75.7% |
| 3315232 | 611.7.1.8 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › RPW8 | 0.69 | 62.0 | 5.81e-01 | 100.0% | 81.4% |
| 3666924 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.69 | 61.0 | 6.15e-01 | 100.0% | 98.3% |
| 4235156 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.69 | 47.0 | 4.71e-01 | 70.7% | 99.2% |
| 3605421 | 1189.1.1.6 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › ISG65-75 | 0.68 | 50.0 | 3.68e-01 | 76.7% | 85.9% |
| 3477777 | 4177.1.1.12 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FAM92 | 0.68 | 49.0 | 3.94e-01 | 75.9% | 78.3% |
| 5040635 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.68 | 47.0 | 4.78e-01 | 71.6% | 73.0% |
| 3192204 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.68 | 59.0 | 5.61e-01 | 97.4% | 100.0% |
| 3685745 | 611.7.1.0 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain | 0.67 | 56.0 | 5.74e-01 | 98.3% | 95.5% |
| 3378402 | 611.7.1.0 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain | 0.67 | 61.0 | 5.82e-01 | 100.0% | 87.4% |
| 3698208 | 611.7.1.0 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain | 0.67 | 60.0 | 5.66e-01 | 100.0% | 95.7% |
| 3351501 | 611.7.1.2 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › MCAfunc | 0.67 | 60.0 | 5.62e-01 | 100.0% | 80.0% |
| 54292 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.67 | 48.0 | 4.82e-01 | 73.3% | 77.4% |
| 3824153 | 611.7.1.11 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › DUF7032 | 0.67 | 60.0 | 5.80e-01 | 100.0% | 92.3% |
| 3363306 | 611.7.1.16 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › PUB2_N | 0.66 | 60.0 | 5.51e-01 | 100.0% | 77.3% |
| 2841860 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.66 | 48.0 | 4.53e-01 | 75.9% | 67.1% |
| 3689007 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.66 | 58.0 | 5.01e-01 | 99.1% | 81.1% |
| 3240929 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.65 | 48.0 | 3.91e-01 | 76.7% | 85.1% |
| 3729299 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.65 | 46.0 | 4.21e-01 | 73.3% | 68.4% |
| 3432194 | 611.8.1.9 ↗ | alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › PGG | 0.65 | 57.0 | 5.28e-01 | 100.0% | 92.3% |
| 3205106 | 192.29.1.151 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PEX11 | 0.65 | 46.0 | 3.46e-01 | 72.4% | 39.4% |
| 3199926 | 611.2.1.0 ↗ | alpha bundles › N-cbl like › N-terminal domain of cbl (N-cbl) › N-terminal domain of cbl (N-cbl) | 0.64 | 54.0 | 5.28e-01 | 91.4% | 95.2% |
| 3370990 | 611.7.1.0 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain | 0.64 | 58.0 | 5.44e-01 | 100.0% | 85.0% |
| 1503807 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.64 | 45.0 | 4.56e-01 | 72.4% | 75.7% |
| 3726746 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.64 | 56.0 | 5.23e-01 | 97.4% | 94.5% |
| 3766437 | 601.16.1.20 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › Insc_C | 0.62 | 44.0 | 4.46e-01 | 75.0% | 74.8% |
| 3535566 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.61 | 44.0 | 4.32e-01 | 76.7% | 68.8% |
| 3612403 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.60 | 55.0 | 5.09e-01 | 99.1% | 90.3% |
| 3320579 | 601.18.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › PsbQ | 0.60 | 54.0 | 4.97e-01 | 100.0% | 87.8% |
| 3315877 | 5059.1.1.8 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Mg_trans_NIPA | 0.60 | 42.0 | 3.90e-01 | 74.1% | 56.8% |
| 3620560 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.59 | 46.0 | 4.28e-01 | 82.8% | 66.0% |
| 3453619 | 601.4.1.12 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › DNA_repr_REX1B | 0.59 | 43.0 | 3.95e-01 | 75.9% | 64.5% |
| 3410594 | 4177.1.1.6 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3_WASP_bdg | 0.59 | 44.0 | 3.67e-01 | 77.6% | 88.3% |
| 4095698 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.56 | 41.0 | 4.15e-01 | 75.9% | 97.4% |
| 3975940 | 601.4.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TorS_sensor_domain | 0.56 | 50.0 | 4.65e-01 | 99.1% | 92.0% |
| 4944333 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.56 | 50.0 | 4.88e-01 | 98.3% | 97.6% |
| 3826941 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.56 | 50.0 | 4.37e-01 | 100.0% | 80.4% |
| 5065387 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.55 | 48.0 | 4.84e-01 | 99.1% | 95.6% |
| 3478235 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.54 | 48.0 | 4.68e-01 | 98.3% | 95.3% |
| 4943286 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.54 | 47.0 | 4.36e-01 | 95.7% | 75.0% |
| 3309205 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.54 | 48.0 | 4.51e-01 | 100.0% | 88.3% |
| 3371270 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.54 | 48.0 | 4.57e-01 | 100.0% | 91.4% |
| 3242888 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.53 | 48.0 | 4.57e-01 | 100.0% | 87.4% |
| 4983897 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.53 | 44.0 | 3.99e-01 | 91.4% | 69.4% |
| 3164482 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.53 | 46.0 | 3.93e-01 | 100.0% | 95.1% |
| 3769992 | 5001.1.1.9 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › TAS2R | 0.52 | 45.0 | 3.42e-01 | 98.3% | 53.1% |
| 5082279 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.52 | 47.0 | 4.67e-01 | 100.0% | 94.2% |
| 3967319 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.52 | 46.0 | 4.55e-01 | 98.3% | 97.6% |
| 3284088 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.52 | 46.0 | 4.43e-01 | 98.3% | 92.3% |
| 3286802 | 601.4.1.58 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › PF27150 | 0.51 | 44.0 | 4.17e-01 | 95.7% | 79.3% |
D2
high
residues 248-409
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06772.17 best | LtrA | 75.1 | 9.00e-21 | 96.3% | 38.6% |
CATH (40)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1r0dA00 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.70 | 58.0 | 5.46e-01 | 87.7% | 81.9% |
| 5gj7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.69 | 51.0 | 5.26e-01 | 75.9% | 90.1% |
| 2ix5A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.69 | 51.0 | 5.23e-01 | 76.5% | 85.2% |
| 1rx0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.68 | 51.0 | 5.22e-01 | 77.2% | 86.5% |
| 5zw7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.68 | 51.0 | 5.23e-01 | 76.5% | 85.5% |
| 2wbiB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.68 | 50.0 | 5.14e-01 | 77.2% | 85.4% |
| 1ivhA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.67 | 50.0 | 5.30e-01 | 75.9% | 91.5% |
| 5iduC03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.67 | 50.0 | 5.05e-01 | 76.5% | 81.8% |
| 4xvxA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.66 | 48.0 | 5.03e-01 | 74.1% | 83.7% |
| 3p4tA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.66 | 49.0 | 5.13e-01 | 77.2% | 89.3% |
| 2jifA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.66 | 49.0 | 5.08e-01 | 77.2% | 85.7% |
| 1egdA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.66 | 49.0 | 5.26e-01 | 77.2% | 92.2% |
| 4doyA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.66 | 50.0 | 4.84e-01 | 79.0% | 94.0% |
| 1dkxA02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.66 | 33.0 | 4.46e-01 | 88.9% | 95.0% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.66 | 45.0 | 4.71e-01 | 77.8% | 74.8% |
| 2jbrA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.65 | 49.0 | 4.76e-01 | 78.4% | 82.2% |
| 2pg0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.65 | 49.0 | 5.08e-01 | 77.2% | 88.6% |
| 8cdaB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.65 | 48.0 | 4.88e-01 | 75.9% | 89.3% |
| 2or0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.65 | 51.0 | 4.85e-01 | 81.5% | 92.5% |
| 1r2jA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.65 | 48.0 | 5.11e-01 | 77.2% | 86.8% |
| 3owaB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.64 | 47.0 | 4.78e-01 | 75.3% | 82.2% |
| 2uxwA01 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.63 | 50.0 | 4.83e-01 | 84.0% | 79.0% |
| 1x8zB00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.63 | 45.0 | 4.76e-01 | 77.8% | 81.6% |
| 2rfqC03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.63 | 48.0 | 4.75e-01 | 80.9% | 91.4% |
| 4od4A02 | 1.20.120.1780 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › UbiA prenyltransferase | 0.62 | 44.0 | 5.05e-01 | 78.4% | 99.2% |
| 2e87A01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.62 | 44.0 | 4.46e-01 | 72.2% | 95.0% |
| 1qoyA00 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.61 | 47.0 | 3.89e-01 | 82.1% | 89.8% |
| 8h8jC01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.59 | 50.0 | 4.26e-01 | 92.6% | 72.3% |
| 4alyB00 | 1.10.3160.10 | Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 | 0.59 | 41.0 | 3.96e-01 | 71.0% | 64.2% |
| 3ljbA00 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.58 | 44.0 | 4.04e-01 | 80.2% | 82.6% |
| 3zciA00 | 1.20.58.1660 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 40.0 | 3.82e-01 | 70.4% | 92.7% |
| 7eq1R01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.57 | 47.0 | 3.87e-01 | 87.0% | 71.4% |
| 1c17M00 | 1.20.120.220 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ATP synthase, F0 complex, subunit A | 0.56 | 41.0 | 4.35e-01 | 75.3% | 95.8% |
| 7rkxR01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.56 | 46.0 | 4.02e-01 | 92.0% | 96.6% |
| 4ehsA00 | 1.10.860.10 | Mainly Alpha › Orthogonal Bundle › DNAb Helicase; Chain A › DNAb Helicase; Chain A | 0.53 | 37.0 | 4.16e-01 | 95.1% | 92.7% |
| 1oohA00 | 1.10.238.20 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain | 0.53 | 34.0 | 3.81e-01 | 98.1% | 83.3% |
| 3axjB01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.52 | 36.0 | 3.69e-01 | 70.4% | 87.7% |
| 1xwmA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.52 | 42.0 | 3.90e-01 | 87.0% | 89.2% |
| 8h4pA01 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.52 | 40.0 | 3.32e-01 | 81.5% | 77.8% |
| 7sf8A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.50 | 46.0 | 4.05e-01 | 100.0% | 69.3% |
ECOD (63)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3631036 | 5069.1.1.38 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Frag1 | 0.70 | 60.0 | 5.85e-01 | 92.6% | 95.6% |
| 3254587 | 1174.1.1.7 ↗ | alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 › Frag1 | 0.69 | 59.0 | 5.29e-01 | 90.7% | 76.8% |
| 3285823 | 633.6.1.0 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like | 0.69 | 51.0 | 5.41e-01 | 77.2% | 90.3% |
| 3476314 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.69 | 51.0 | 5.56e-01 | 77.8% | 94.8% |
| 3911777 | 633.10.1.15 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › Transmemb_17 | 0.68 | 51.0 | 5.48e-01 | 77.8% | 91.9% |
| 3486843 | 5069.1.1.38 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Frag1 | 0.68 | 58.0 | 5.21e-01 | 92.0% | 79.6% |
| 5071165 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.67 | 50.0 | 5.25e-01 | 77.8% | 90.7% |
| 3271008 | 5001.1.1.8 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HlyIII | 0.67 | 57.0 | 5.07e-01 | 93.2% | 64.8% |
| 3995562 | 602.2.1.0 ↗ | alpha arrays › L-aspartase middle domain-like › RNA-binding protein She2p › RNA-binding protein She2p | 0.67 | 57.0 | 4.96e-01 | 92.0% | 72.2% |
| 3363364 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.66 | 46.0 | 5.00e-01 | 70.4% | 94.1% |
| 3318287 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.66 | 49.0 | 4.80e-01 | 77.2% | 71.7% |
| 2879019 | 633.6.1.4 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_2 | 0.66 | 51.0 | 5.15e-01 | 80.9% | 88.8% |
| 3803172 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.66 | 46.0 | 4.63e-01 | 77.2% | 71.2% |
| 4958843 | 3543.1.1.13 ↗ | alpha complex topology › Acid-activated urea channel › Acid-activated urea channel › Acid-activated urea channel › DUF308 | 0.66 | 54.0 | 5.25e-01 | 91.4% | 78.9% |
| 4943269 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.65 | 55.0 | 4.85e-01 | 91.4% | 69.6% |
| 3802836 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.65 | 48.0 | 4.74e-01 | 77.2% | 73.1% |
| 3967249 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.65 | 53.0 | 5.07e-01 | 92.0% | 75.3% |
| 3641736 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.64 | 46.0 | 4.65e-01 | 79.0% | 71.5% |
| 3486497 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.64 | 47.0 | 5.19e-01 | 75.9% | 100.0% |
| 3401839 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.64 | 47.0 | 5.13e-01 | 77.2% | 91.9% |
| 3348350 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.64 | 48.0 | 4.79e-01 | 77.8% | 76.5% |
| 3181902 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.64 | 54.0 | 5.43e-01 | 90.1% | 91.5% |
| 4434583 | 5001.1.1.8 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HlyIII | 0.64 | 55.0 | 4.94e-01 | 92.6% | 91.5% |
| 3679054 | 601.1.1.40 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › PGG | 0.64 | 46.0 | 4.94e-01 | 74.7% | 97.9% |
| 3346434 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.64 | 48.0 | 4.87e-01 | 79.0% | 79.4% |
| 3322168 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.64 | 47.0 | 4.67e-01 | 77.8% | 72.4% |
| 3326634 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.62 | 47.0 | 4.65e-01 | 78.4% | 77.1% |
| 3826788 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.62 | 47.0 | 4.62e-01 | 78.4% | 76.9% |
| 5045751 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.61 | 50.0 | 4.25e-01 | 85.8% | 78.5% |
| 3725136 | 601.1.1.77 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DUF3176 | 0.61 | 44.0 | 4.25e-01 | 73.5% | 87.2% |
| 3487524 | 133.1.1.1 ↗ | alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF | 0.61 | 45.0 | 4.26e-01 | 76.5% | 75.9% |
| 3741788 | 633.21.1.10 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › MARVEL | 0.61 | 44.0 | 4.56e-01 | 75.9% | 95.5% |
| 3534658 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.60 | 45.0 | 4.56e-01 | 77.2% | 87.5% |
| 4117026 | 5069.1.1.56 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › PF27518 | 0.60 | 43.0 | 3.87e-01 | 72.8% | 59.6% |
| 5010859 | 1075.1.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain | 0.60 | 37.0 | 3.39e-01 | 100.0% | 45.7% |
| 3930691 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.60 | 51.0 | 4.22e-01 | 93.2% | 65.3% |
| 3548233 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.60 | 44.0 | 4.47e-01 | 77.2% | 91.5% |
| 3598975 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.60 | 45.0 | 4.49e-01 | 78.4% | 74.7% |
| 3225511 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.60 | 46.0 | 4.63e-01 | 80.2% | 96.2% |
| 3743351 | 611.9.1.6 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Ran-binding | 0.59 | 42.0 | 4.29e-01 | 71.0% | 82.6% |
| 3762118 | 633.21.1.23 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 | 0.59 | 44.0 | 4.41e-01 | 77.2% | 89.1% |
| 4020503 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.58 | 52.0 | 3.94e-01 | 96.3% | 92.4% |
| 3934932 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.58 | 42.0 | 4.52e-01 | 75.3% | 95.0% |
| 3899721 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.58 | 43.0 | 4.31e-01 | 77.2% | 85.5% |
| 3869365 | 633.23.1.22 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL | 0.57 | 42.0 | 4.39e-01 | 75.9% | 98.7% |
| 5023678 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.57 | 47.0 | 4.46e-01 | 87.7% | 95.3% |
| 3901994 | 633.23.1.22 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL | 0.57 | 41.0 | 4.43e-01 | 73.5% | 100.0% |
| 4958277 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.56 | 39.0 | 3.71e-01 | 71.0% | 65.1% |
| 4099449 | 141.1.1.3 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA | 0.56 | 51.0 | 4.37e-01 | 99.4% | 87.8% |
| 3523336 | 174.1.1.12 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › BCLP | 0.55 | 42.0 | 4.18e-01 | 79.6% | 80.0% |
| 4299710 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.55 | 41.0 | 4.00e-01 | 77.2% | 74.4% |
| 4542751 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.55 | 41.0 | 4.16e-01 | 78.4% | 85.0% |
| 3929423 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.54 | 46.0 | 3.82e-01 | 93.2% | 88.5% |
| 4973300 | 1075.5.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt | 0.54 | 40.0 | 3.76e-01 | 78.4% | 94.3% |
| 3213238 | 5054.1.1.61 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › ELO | 0.54 | 42.0 | 3.73e-01 | 83.3% | 82.1% |
| 5081835 | 1075.5.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt | 0.53 | 38.0 | 3.60e-01 | 74.1% | 61.0% |
| 3163855 | 5069.1.1.56 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › PF27518 | 0.53 | 39.0 | 3.52e-01 | 88.9% | 53.6% |
| 5009372 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 46.0 | 4.18e-01 | 93.8% | 72.6% |
| 4032683 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.52 | 42.0 | 3.90e-01 | 87.7% | 90.2% |
| 4929461 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.52 | 38.0 | 3.60e-01 | 75.3% | 96.9% |
| 4297941 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.51 | 44.0 | 3.94e-01 | 95.1% | 72.1% |
| 4997681 | 1075.5.1.8 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 | 0.51 | 37.0 | 3.51e-01 | 73.5% | 63.1% |
| 3989529 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.50 | 45.0 | 3.98e-01 | 100.0% | 95.0% |