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CAKLQF020000033.1__CAH1095391.1__SAMEA5780031_03899__00021

Bact-Vir

CAKLQF020000033.1__CAH1095391.1__SAMEA5780031_03899__00021

Identity

Kingdom:
phage

Quality

94.8 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1-77
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04172.22 best LrgB 38.4 1.30e-09 87.0% 30.8%
CATH (27)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3ckdA02 1.20.58.360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Shigella T3SS effector IpaH defines 0.71 52.0 4.33e-01 76.6% 65.3%
3d5lA03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.64 41.0 4.72e-01 84.4% 98.1%
4ixjA01 3.30.1300.80 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › 0.63 46.0 4.60e-01 76.6% 94.8%
3ousA00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.61 42.0 4.11e-01 71.4% 98.8%
3e3vA03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.61 42.0 4.60e-01 85.7% 100.0%
1u61A00 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.60 45.0 3.82e-01 79.2% 62.2%
5dn6J00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.60 39.0 4.00e-01 72.7% 68.9%
2v6yA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.60 44.0 4.46e-01 87.0% 80.0%
1j5wA02 1.20.58.180 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 0.57 41.0 4.11e-01 85.7% 75.3%
1hs7A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 43.0 4.04e-01 83.1% 72.2%
2p5tA00 1.10.8.130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.56 38.0 3.60e-01 70.1% 69.6%
2qffA00 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.56 36.0 3.66e-01 75.3% 66.2%
5mmjo00 1.10.287.10 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding 0.55 42.0 4.34e-01 83.1% 88.0%
1wkbA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.55 45.0 3.90e-01 89.6% 70.2%
2k3qA00 1.10.274.70 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, N-terminal domain 0.55 46.0 4.09e-01 97.4% 73.7%
4oe8C00 1.10.8.1170 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.55 37.0 3.62e-01 79.2% 62.1%
3vkgA02 1.20.140.100 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain 0.55 38.0 3.05e-01 71.4% 37.4%
2ptfB02 1.20.58.290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121. 0.54 35.0 3.87e-01 81.8% 87.7%
4i8qA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.54 41.0 2.81e-01 83.1% 28.1%
3a7mA01 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.54 41.0 3.69e-01 83.1% 59.1%
4wr4A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.53 40.0 3.64e-01 81.8% 63.8%
2hg2A01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.53 40.0 2.81e-01 85.7% 72.0%
1vh6A01 6.10.140.1940 Special › Helix non-globular › Helix Hairpins › 0.52 32.0 3.06e-01 71.4% 48.5%
1gt0D00 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.52 38.0 3.83e-01 79.2% 88.6%
1ez0B01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.52 41.0 2.79e-01 89.6% 71.2%
2dw4A03 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.51 39.0 3.55e-01 81.8% 72.3%
4nmyA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.50 43.0 3.25e-01 97.4% 75.1%
ECOD (14)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3743070 601.4.1.60 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TMD0_ABC 0.65 44.0 3.53e-01 71.4% 70.3%
3229748 1134.1.1.9 alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain › RSLD_CPSF6 0.63 45.0 4.37e-01 83.1% 67.1%
3943035 639.2.1.0 alpha arrays › HHA-like › Regulator of acid resistance influenced by indole (AriR) › Regulator of acid resistance influenced by indole (AriR) 0.63 47.0 5.07e-01 83.1% 93.8%
3741745 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.62 41.0 3.43e-01 77.9% 40.8%
4017461 3860.1.1.0 alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm 0.60 48.0 4.48e-01 89.6% 94.0%
3592587 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.58 40.0 3.38e-01 71.4% 44.0%
4993593 198.1.1.27 alpha arrays › Saposin-like › Saposin-like › Saposin-like › PF27234 0.58 44.0 4.41e-01 96.1% 82.5%
4384750 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.57 41.0 3.80e-01 74.0% 63.2%
3309583 604.12.1.65 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT_ATG1 0.56 45.0 4.46e-01 87.0% 86.3%
4955751 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.54 36.0 3.49e-01 70.1% 61.1%
4286656 140.1.1.11 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_1 0.52 39.0 3.55e-01 81.8% 59.1%
4960441 5076.2.1.18 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › DUF6159 0.51 42.0 3.00e-01 92.2% 78.0%
4983118 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.51 38.0 3.58e-01 80.5% 69.5%
5078792 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.50 42.0 3.73e-01 92.2% 64.5%
D2 high residues 85-221
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04172.22 best LrgB 117.9 6.30e-34 98.5% 62.6%
CATH (17)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6wk3A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.61 36.0 3.55e-01 100.0% 53.1%
3zuxA00 1.20.1530.20 Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › 0.60 46.0 3.53e-01 79.6% 79.2%
3godB02 1.20.120.920 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain 0.60 43.0 3.76e-01 73.0% 70.2%
3h36A00 1.10.10.400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain 0.60 36.0 4.34e-01 96.4% 100.0%
4bwzA00 1.20.1530.20 Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › 0.59 45.0 3.26e-01 80.3% 78.4%
2rasA01 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.57 35.0 3.18e-01 99.3% 42.9%
4w8kA02 1.20.120.920 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain 0.57 39.0 3.47e-01 70.8% 67.7%
2o38A01 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.56 24.0 3.31e-01 91.2% 80.0%
2wzkA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.54 34.0 3.78e-01 76.6% 78.2%
4kwaB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 41.0 3.67e-01 78.1% 85.9%
1zklA00 1.10.1300.10 Mainly Alpha › Orthogonal Bundle › Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b › 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain 0.54 40.0 3.09e-01 78.1% 81.7%
4qndA00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.53 30.0 3.53e-01 99.3% 78.4%
3fnbA01 1.20.1440.110 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase 0.53 38.0 4.09e-01 80.3% 87.7%
3pasA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.53 38.0 3.44e-01 73.0% 86.8%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.52 33.0 3.67e-01 88.3% 81.1%
2np5D00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 33.0 3.20e-01 93.4% 53.8%
3ppbA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.51 37.0 3.40e-01 75.9% 82.4%
ECOD (34)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3944373 101.35.1.20 alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › LrgB 0.95 92.0 7.50e-01 100.0% 61.3%
3313984 3236.2.1.9 alpha complex topology › Cation-proton antiporter › Sodium-dependent citrate symporter › Sodium-dependent citrate symporter › LrgB 0.94 92.0 6.16e-01 100.0% 33.6%
3326984 3236.1.1.8 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › LrgB 0.94 91.0 6.21e-01 100.0% 35.3%
3833821 3236.1.1.8 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › LrgB 0.94 91.0 6.91e-01 100.0% 51.1%
3192498 3236.2.1.9 alpha complex topology › Cation-proton antiporter › Sodium-dependent citrate symporter › Sodium-dependent citrate symporter › LrgB 0.91 87.0 6.00e-01 100.0% 35.5%
3789219 3236.2.1.9 alpha complex topology › Cation-proton antiporter › Sodium-dependent citrate symporter › Sodium-dependent citrate symporter › LrgB 0.90 86.0 6.02e-01 100.0% 36.9%
4247906 3236.1.1.12 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Cons_hypoth698 0.89 85.0 6.18e-01 100.0% 44.8%
3283067 3236.1.1.12 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Cons_hypoth698 0.87 83.0 6.23e-01 100.0% 48.7%
4153765 3236.1.1.12 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Cons_hypoth698 0.87 83.0 6.00e-01 100.0% 42.6%
4286776 3236.1.1.12 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Cons_hypoth698 0.86 81.0 5.99e-01 100.0% 45.5%
4044418 3236.1.1.12 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Cons_hypoth698 0.85 80.0 5.86e-01 100.0% 44.5%
3194748 3236.1.1.8 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › LrgB 0.82 78.0 5.23e-01 100.0% 31.0%
3839141 3236.2.1.7 alpha complex topology › Cation-proton antiporter › Sodium-dependent citrate symporter › Sodium-dependent citrate symporter › Glt_symporter 0.82 77.0 5.36e-01 100.0% 76.9%
3967733 3236.2.1.7 alpha complex topology › Cation-proton antiporter › Sodium-dependent citrate symporter › Sodium-dependent citrate symporter › Glt_symporter 0.82 75.0 5.29e-01 98.5% 77.7%
4643781 3236.1.1.16 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Asp-Al_Ex 0.81 76.0 5.40e-01 100.0% 76.5%
4141634 3236.2.1.8 alpha complex topology › Cation-proton antiporter › Sodium-dependent citrate symporter › Sodium-dependent citrate symporter › Asp-Al_Ex 0.81 75.0 5.46e-01 100.0% 76.3%
3941415 3236.1.1.18 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › AbrB 0.80 75.0 5.97e-01 100.0% 100.0%
4361189 610.4.1.1 alpha arrays › ERP29 C domain-like › YqeY domain › YqeY domain › YqeY 0.64 39.0 3.70e-01 99.3% 48.8%
3581139 131.1.1.1 alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › PDEase_I 0.63 43.0 3.74e-01 96.4% 47.0%
3388437 3236.1.1.3 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Mem_trans 0.63 49.0 3.78e-01 81.0% 82.2%
4099056 3236.1.1.3 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Mem_trans 0.61 46.0 3.53e-01 78.8% 80.0%
3193583 4207.1.1.0 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) 0.60 32.0 3.23e-01 100.0% 50.7%
4963036 3236.1.1.3 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Mem_trans 0.59 45.0 3.45e-01 81.0% 80.9%
3949330 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.57 42.0 3.52e-01 75.2% 90.5%
4949710 3236.1.1.1 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.57 46.0 3.27e-01 84.7% 77.0%
3209386 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 50.0 3.23e-01 98.5% 21.3%
3564899 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.54 40.0 3.49e-01 77.4% 93.3%
3563914 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.54 42.0 3.55e-01 80.3% 89.5%
5020945 3236.1.1.1 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.54 41.0 3.01e-01 81.0% 75.2%
5063507 3236.1.1.1 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.53 41.0 3.05e-01 81.8% 77.9%
3172285 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 39.0 3.16e-01 80.3% 71.9%
3609292 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.51 39.0 3.37e-01 81.0% 91.4%
3969344 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.51 38.0 3.43e-01 78.8% 95.3%
4009467 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 40.0 3.54e-01 85.4% 89.5%