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CAKLQH020000009.1__CAH1084288.1__SAMEA5780036_01752__00113
Bact-VirCAKLQH020000009.1__CAH1084288.1__SAMEA5780036_01752__00113
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 1-174
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF09335.17 best | VTT_dom | 82.6 | 4.60e-23 | 73.0% | 99.2% |
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.61 | 29.0 | 3.46e-01 | 76.4% | 64.7% |
| 5wp3B00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.58 | 32.0 | 4.09e-01 | 77.0% | 90.2% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.55 | 37.0 | 4.15e-01 | 76.4% | 88.0% |
| 2oerA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 45.0 | 4.49e-01 | 92.0% | 82.7% |
| 1gu9C00 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.55 | 32.0 | 3.31e-01 | 88.5% | 57.7% |
| 3ubcA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.54 | 30.0 | 3.46e-01 | 86.8% | 71.0% |
| 1hbgA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.54 | 34.0 | 3.64e-01 | 86.8% | 72.1% |
| 2wzkA02 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.54 | 38.0 | 4.40e-01 | 74.7% | 99.2% |
| 4mndA02 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.54 | 45.0 | 4.36e-01 | 88.5% | 91.1% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.54 | 31.0 | 3.51e-01 | 74.7% | 73.1% |
| 1f1mA00 | 1.20.120.240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 | 0.53 | 32.0 | 3.32e-01 | 74.7% | 63.6% |
| 3cllA00 | 1.20.1080.10 | Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. | 0.52 | 44.0 | 3.95e-01 | 89.1% | 98.3% |
ECOD (52)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4171353 | 3291.1.1.212 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › VTT_dom | 0.89 | 78.0 | 7.38e-01 | 91.4% | 78.5% |
| 3165509 | 3470.1.1.41 ↗ | extended segments › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain › VTT_dom | 0.86 | 76.0 | 7.82e-01 | 90.8% | 96.4% |
| 5038416 | 604.39.1.12 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › VTT_dom | 0.84 | 66.0 | 6.72e-01 | 86.8% | 82.9% |
| 3947566 | 604.39.1.12 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › VTT_dom | 0.82 | 64.0 | 7.12e-01 | 87.4% | 100.0% |
| 3546908 | 604.39.1.12 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › VTT_dom | 0.81 | 72.0 | 6.68e-01 | 97.7% | 75.8% |
| 4947293 | 604.39.1.0 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters | 0.80 | 62.0 | 6.83e-01 | 86.8% | 100.0% |
| 5053081 | 604.39.1.12 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › VTT_dom | 0.78 | 69.0 | 6.47e-01 | 97.7% | 77.6% |
| 4373354 | 604.39.1.12 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › VTT_dom | 0.78 | 61.0 | 5.82e-01 | 86.8% | 70.0% |
| 3349933 | 109.4.1.1172 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › VTT_dom | 0.78 | 61.0 | 6.71e-01 | 85.6% | 100.0% |
| 3526446 | 604.39.1.12 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › VTT_dom | 0.76 | 61.0 | 6.65e-01 | 87.9% | 99.3% |
| 3251662 | 604.39.1.12 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › VTT_dom | 0.76 | 65.0 | 6.25e-01 | 93.1% | 80.5% |
| 3861774 | 604.39.1.12 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › VTT_dom | 0.74 | 67.0 | 5.95e-01 | 97.7% | 69.2% |
| 3651564 | 604.39.1.12 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › VTT_dom | 0.74 | 67.0 | 6.11e-01 | 97.7% | 75.0% |
| 3219117 | 604.39.1.12 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › VTT_dom | 0.72 | 65.0 | 6.28e-01 | 97.7% | 85.1% |
| 3500376 | 604.39.1.12 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › VTT_dom | 0.71 | 65.0 | 5.95e-01 | 97.7% | 75.9% |
| 3382170 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.70 | 38.0 | 4.00e-01 | 80.5% | 57.5% |
| 2440128 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.69 | 41.0 | 3.74e-01 | 76.4% | 45.3% |
| 5064159 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.68 | 41.0 | 3.75e-01 | 78.2% | 46.8% |
| 3320297 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.68 | 41.0 | 3.70e-01 | 78.2% | 43.8% |
| 3726677 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.67 | 41.0 | 3.73e-01 | 78.2% | 45.2% |
| 5063887 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.67 | 40.0 | 3.69e-01 | 77.0% | 45.9% |
| 3326403 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.67 | 41.0 | 3.67e-01 | 78.7% | 43.8% |
| 5058662 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.66 | 40.0 | 3.69e-01 | 77.0% | 46.8% |
| 3598304 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.65 | 40.0 | 3.73e-01 | 78.2% | 48.4% |
| 5040597 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.64 | 38.0 | 3.68e-01 | 78.2% | 51.6% |
| 3419853 | 192.29.1.19 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon | 0.64 | 34.0 | 3.73e-01 | 73.6% | 60.7% |
| 3612901 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.63 | 40.0 | 3.64e-01 | 78.2% | 46.8% |
| 3839827 | 1075.5.1.2 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ | 0.62 | 38.0 | 3.49e-01 | 78.2% | 46.1% |
| 3971975 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.61 | 38.0 | 3.47e-01 | 77.6% | 48.0% |
| 3164066 | 1075.5.1.2 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ | 0.59 | 39.0 | 3.28e-01 | 78.7% | 39.0% |
| 3976030 | 1075.5.1.2 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ | 0.59 | 37.0 | 3.36e-01 | 77.6% | 45.1% |
| 4522145 | 5050.1.1.54 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Mntp | 0.59 | 43.0 | 4.27e-01 | 74.1% | 75.6% |
| 3590115 | 1075.1.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_3 | 0.59 | 48.0 | 4.21e-01 | 86.8% | 62.7% |
| 4988860 | 1076.1.1.0 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related | 0.58 | 47.0 | 4.69e-01 | 94.3% | 85.1% |
| 4528918 | 1079.1.1.13 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Mntp | 0.58 | 42.0 | 4.20e-01 | 74.1% | 76.6% |
| 3267624 | 192.29.1.19 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon | 0.56 | 35.0 | 3.88e-01 | 75.9% | 77.0% |
| 5004675 | 5050.1.1.53 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MarC | 0.56 | 41.0 | 3.98e-01 | 75.3% | 78.0% |
| 3989510 | 1075.1.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_3 | 0.56 | 47.0 | 4.09e-01 | 87.4% | 62.7% |
| 5057964 | 3883.1.1.1 ↗ | alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf | 0.56 | 47.0 | 4.73e-01 | 89.7% | 94.9% |
| 4031515 | 1075.1.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_3 | 0.55 | 46.0 | 3.96e-01 | 87.9% | 64.4% |
| 4990026 | 1075.5.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt | 0.54 | 39.0 | 3.74e-01 | 74.1% | 76.0% |
| 3317565 | 3831.1.1.0 ↗ | alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 | 0.53 | 25.0 | 3.07e-01 | 100.0% | 67.0% |
| 3279812 | 1075.1.2.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain | 0.53 | 42.0 | 4.58e-01 | 86.8% | 100.0% |
| 4275097 | 601.19.1.34 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › DUF5453 | 0.53 | 36.0 | 3.72e-01 | 78.2% | 73.1% |
| 3237985 | 150.1.1.24 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Prominin | 0.53 | 33.0 | 2.97e-01 | 78.7% | 42.0% |
| 5016583 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.52 | 39.0 | 3.67e-01 | 75.9% | 76.7% |
| 4029964 | 3871.1.1.1 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN | 0.52 | 33.0 | 3.47e-01 | 81.6% | 70.3% |
| 5002537 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.52 | 38.0 | 3.50e-01 | 75.9% | 70.4% |
| 5020781 | 1075.1.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_3 | 0.51 | 42.0 | 3.77e-01 | 88.5% | 99.2% |
| 4967541 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.51 | 37.0 | 3.64e-01 | 75.3% | 79.5% |
| 3173226 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.51 | 39.0 | 3.54e-01 | 79.3% | 73.5% |
| 5009376 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.50 | 40.0 | 4.28e-01 | 86.8% | 100.0% |