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CAKLQH020000014.1CAH1087959.1SAMEA5780036_02221__00048

Bact-Vir

CAKLQH020000014.1__CAH1087959.1__SAMEA5780036_02221__00048

Identity

Kingdom:: phage

Quality

79.8 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 62-169

PDB

Domain cluster: representative

CATH (39)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3kyeA00	3.30.450.30	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic	0.78	60.0	5.83e-01	79.6%	83.2%
1skoA00	3.30.450.30	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic	0.77	59.0	5.74e-01	80.6%	83.2%
1skoB00	3.30.450.30	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic	0.77	59.0	5.74e-01	79.6%	83.6%
4ywzB00	3.30.450.20	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain	0.74	68.0	6.13e-01	100.0%	83.6%
7ct3A01	3.30.450.30	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic	0.74	54.0	5.30e-01	75.9%	83.8%
3by8A00	3.30.450.20	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain	0.73	67.0	6.24e-01	100.0%	90.2%
1p0zA00	3.30.450.20	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain	0.73	66.0	6.19e-01	100.0%	87.0%
3cwfA00	3.30.450.20	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain	0.72	58.0	5.81e-01	93.5%	85.2%
1j3wC00	3.30.450.30	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic	0.71	59.0	5.50e-01	88.0%	81.2%
5hwtB00	3.30.450.20	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain	0.70	49.0	4.72e-01	71.3%	93.4%
7yh1A01	3.30.450.30	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic	0.70	58.0	5.69e-01	87.0%	86.0%
3b33A00	3.30.450.20	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain	0.70	51.0	5.10e-01	75.0%	100.0%
3r4kA02	3.30.450.40	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain	0.69	56.0	4.73e-01	87.0%	82.1%
3ms6A00	3.30.450.30	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic	0.69	54.0	5.92e-01	92.6%	100.0%
2xrnA02	3.30.450.40	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain	0.69	56.0	4.77e-01	88.0%	83.1%
4lrzE01	3.30.450.40	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain	0.68	55.0	4.64e-01	86.1%	68.0%
5tjjB02	3.30.450.40	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain	0.68	55.0	4.65e-01	87.0%	85.4%
5hpfA00	3.30.450.40	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain	0.68	55.0	4.69e-01	87.0%	86.9%
3lidA03	3.30.450.20	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain	0.67	48.0	5.09e-01	75.0%	99.0%
3d3oA00	3.30.450.40	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain	0.66	56.0	4.71e-01	90.7%	84.7%
5y6iA02	3.30.450.40	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain	0.65	54.0	4.72e-01	88.9%	85.7%
3oloA00	3.30.450.20	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain	0.64	53.0	5.29e-01	88.0%	99.1%
3by9B01	3.30.450.20	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain	0.64	55.0	5.20e-01	94.4%	91.6%
4kqdB00	3.30.450.20	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain	0.63	55.0	5.44e-01	94.4%	95.7%
3k3dA00	3.30.450.20	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain	0.62	55.0	5.28e-01	97.2%	98.4%
4hh2C04	3.30.450.20	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain	0.61	53.0	5.20e-01	92.6%	96.6%
7jsnA02	3.30.450.40	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain	0.61	53.0	4.32e-01	97.2%	84.5%
3lyxB00	3.30.450.20	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain	0.60	52.0	5.09e-01	95.4%	97.5%
4nkpA01	3.30.450.150	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Haem-degrading domain	0.58	46.0	4.38e-01	86.1%	86.9%
2pd8B00	3.30.450.20	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain	0.57	49.0	4.45e-01	91.7%	98.6%
3fpwA01	3.30.450.150	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Haem-degrading domain	0.57	46.0	4.37e-01	87.0%	88.0%
6kghA02	3.30.450.330	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase ›	0.56	43.0	3.87e-01	82.4%	74.7%
3caxA02	3.30.450.20	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain	0.55	47.0	4.38e-01	93.5%	87.0%
8ciwA02	2.40.110.10	Mainly Beta › Beta Barrel › Butyryl-CoA Dehydrogenase, subunit A; domain 2 › Butyryl-CoA Dehydrogenase, subunit A, domain 2	0.55	43.0	4.09e-01	86.1%	82.0%
2qkpD00	3.30.450.20	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain	0.55	49.0	4.53e-01	97.2%	94.0%
4mn5A00	3.30.450.20	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain	0.54	47.0	4.84e-01	95.4%	99.0%
2xepB02	3.40.710.10	Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily	0.54	48.0	3.63e-01	99.1%	90.2%
2nn5A00	3.30.530.20	Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain	0.53	40.0	3.51e-01	81.5%	69.0%
4meeA00	2.40.128.130	Mainly Beta › Beta Barrel › Lipocalin › Autotransporter beta-domain	0.50	41.0	2.97e-01	88.0%	99.7%

ECOD (89)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
390348	223.1.1.47 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains › HK_sensor_dom_bact	0.79	73.0	6.18e-01	100.0%	80.0%
4139591	223.2.1.32 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like › Fuz_longin_2	0.78	64.0	5.52e-01	86.1%	78.8%
5053333	223.2.1.0 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like	0.78	61.0	5.59e-01	81.5%	77.8%
4972247	223.2.1.0 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like	0.78	62.0	5.78e-01	83.3%	77.7%
5040627	223.2.1.5 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like › Robl_LC7	0.78	63.0	5.90e-01	85.2%	81.5%
5053192	223.2.1.0 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like	0.77	63.0	5.85e-01	87.0%	85.1%
2855513	223.1.1.0 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains	0.77	71.0	5.00e-01	100.0%	89.6%
5035198	223.1.1.0 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains	0.77	71.0	5.81e-01	100.0%	65.3%
4979132	223.2.1.5 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like › Robl_LC7	0.77	59.0	5.60e-01	80.6%	82.0%
3967419	223.1.1.18 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains › sCache_4	0.76	58.0	5.17e-01	100.0%	57.3%
4045675	223.1.1.81 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains › Cache_WalK	0.76	70.0	5.63e-01	100.0%	62.0%
4670966	223.1.1.81 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains › Cache_WalK	0.76	69.0	6.40e-01	99.1%	89.6%
3203822	223.2.1.0 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like	0.76	65.0	5.45e-01	90.7%	83.4%
4996848	223.2.1.0 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like	0.76	59.0	5.71e-01	81.5%	81.7%
5047768	223.2.1.0 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like	0.76	61.0	5.55e-01	84.3%	76.8%
5050348	223.2.1.5 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like › Robl_LC7	0.76	58.0	5.38e-01	80.6%	75.6%
5048237	223.2.1.5 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like › Robl_LC7	0.76	59.0	5.67e-01	82.4%	83.1%
4994595	223.2.1.5 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like › Robl_LC7	0.75	60.0	5.50e-01	83.3%	80.0%
4948154	223.2.1.0 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like	0.75	60.0	5.69e-01	83.3%	80.0%
5052689	223.2.1.5 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like › Robl_LC7	0.75	62.0	5.90e-01	87.0%	81.6%
4119134	223.1.1.35 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains › sCache_3_2	0.74	69.0	5.49e-01	100.0%	63.9%
5044707	223.2.1.5 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like › Robl_LC7	0.74	60.0	5.65e-01	84.3%	80.8%
4983266	223.2.1.5 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like › Robl_LC7	0.74	59.0	5.55e-01	84.3%	78.5%
4945992	223.2.1.0 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like	0.74	60.0	5.61e-01	85.2%	81.4%
4189433	223.1.1.81 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains › Cache_WalK	0.74	67.0	5.46e-01	100.0%	62.0%
4254287	223.1.1.35 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains › sCache_3_2	0.74	68.0	5.42e-01	100.0%	56.6%
5079401	223.2.1.0 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like	0.74	60.0	5.66e-01	87.0%	78.5%
5048561	223.2.1.0 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like	0.73	54.0	5.24e-01	76.9%	85.0%
4674295	223.1.1.43 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains › CusS	0.73	67.0	5.59e-01	100.0%	59.4%
5078870	223.2.1.5 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like › Robl_LC7	0.73	60.0	5.44e-01	86.1%	75.0%
6839	223.1.1.35 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains › sCache_3_2	0.73	67.0	6.24e-01	100.0%	90.2%
4297645	5043.1.1.19 ↗	extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like › CusS	0.73	67.0	5.64e-01	100.0%	61.1%
4541933	223.1.1.43 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains › CusS	0.73	67.0	5.85e-01	100.0%	71.9%
4943155	223.2.1.0 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like	0.73	58.0	5.59e-01	83.3%	84.2%
4948155	223.2.1.0 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like	0.73	59.0	5.51e-01	85.2%	80.0%
428274	223.2.1.5 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like › Robl_LC7	0.73	60.0	5.52e-01	87.0%	79.4%
3985763	223.1.1.35 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains › sCache_3_2	0.73	66.0	5.33e-01	100.0%	64.4%
4673949	223.1.1.0 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains	0.73	66.0	5.29e-01	100.0%	62.9%
5003862	223.2.1.0 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like	0.73	59.0	5.41e-01	86.1%	73.6%
4961203	223.2.1.5 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like › Robl_LC7	0.72	58.0	5.58e-01	85.2%	82.3%
4413356	223.1.1.18 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains › sCache_4	0.72	66.0	5.49e-01	100.0%	61.6%
198782	223.1.1.33 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains › sCache_like	0.72	58.0	5.81e-01	93.5%	85.2%
3973081	223.1.1.0 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains	0.72	66.0	5.58e-01	100.0%	64.6%
5049758	223.2.1.5 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like › Robl_LC7	0.72	58.0	5.26e-01	86.1%	73.8%
4957253	223.2.1.5 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like › Robl_LC7	0.72	58.0	5.53e-01	85.2%	82.1%
5050494	223.2.1.5 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like › Robl_LC7	0.72	58.0	5.47e-01	86.1%	80.0%
4927500	223.2.1.0 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like	0.72	60.0	5.49e-01	88.0%	80.0%
4399650	223.1.1.59 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains › ArlS_N	0.71	62.0	5.24e-01	100.0%	58.3%
3965700	223.2.1.5 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like › Robl_LC7	0.71	59.0	5.68e-01	87.0%	83.2%
5072402	223.2.1.5 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like › Robl_LC7	0.71	57.0	5.47e-01	86.1%	82.4%
4928738	223.2.1.0 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like	0.71	59.0	5.57e-01	88.9%	84.4%
5065367	223.2.1.0 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like	0.70	59.0	5.45e-01	88.9%	76.3%
4977856	223.2.1.5 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like › Robl_LC7	0.70	59.0	5.40e-01	88.0%	74.1%
4987450	223.1.1.0 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains	0.70	64.0	5.52e-01	100.0%	65.5%
4156259	223.1.1.0 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains	0.70	64.0	4.60e-01	100.0%	86.7%
5052872	223.2.1.5 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like › Robl_LC7	0.70	58.0	5.45e-01	88.0%	82.2%
3967866	223.1.1.61 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains › SMP_2	0.70	55.0	4.90e-01	100.0%	60.0%
4191473	223.1.1.59 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains › ArlS_N	0.70	60.0	5.92e-01	100.0%	87.8%
5000860	223.2.1.5 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like › Robl_LC7	0.70	59.0	5.53e-01	89.8%	82.3%
5052344	223.2.1.0 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like	0.70	60.0	5.59e-01	90.7%	80.8%
3058519	223.2.1.5 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like › Robl_LC7	0.69	58.0	5.63e-01	88.0%	84.5%
4927093	223.2.1.0 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like	0.69	56.0	5.33e-01	87.0%	84.4%
4431434	223.1.1.43 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains › CusS	0.69	62.0	5.33e-01	100.0%	64.7%
4592301	223.1.1.0 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains	0.69	55.0	5.39e-01	84.3%	97.4%
4134441	223.1.1.0 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains	0.68	60.0	5.77e-01	97.2%	88.8%
5049672	223.2.1.0 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like	0.68	54.0	5.38e-01	90.7%	81.8%
3977310	223.1.1.0 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains	0.67	53.0	5.14e-01	83.3%	80.8%
3973210	223.1.1.0 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains	0.67	56.0	5.70e-01	93.5%	91.4%
3969073	223.1.1.3 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains › GAF	0.67	56.0	4.63e-01	89.8%	65.8%
3950403	223.1.1.2 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains › PAS	0.66	58.0	5.44e-01	93.5%	99.2%
5007519	223.2.1.64 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like › PF27410	0.66	54.0	5.41e-01	86.1%	85.5%
4317800	223.1.1.0 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains	0.66	59.0	5.41e-01	100.0%	75.0%
5050158	223.2.1.0 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like	0.66	59.0	5.04e-01	97.2%	78.2%
3623755	223.2.1.16 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like › LAMTOR5	0.66	53.0	5.22e-01	86.1%	87.8%
4928123	223.2.1.0 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like	0.66	55.0	5.19e-01	89.8%	82.3%
3967308	605.1.1.0 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase	0.65	58.0	5.06e-01	100.0%	65.5%
4929561	223.2.1.62 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like › DUF6659	0.65	55.0	5.23e-01	90.7%	81.6%
3977154	223.1.1.0 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains	0.64	59.0	5.59e-01	100.0%	86.4%
3282232	223.1.1.0 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains	0.64	56.0	4.97e-01	94.4%	68.0%
3969782	223.1.1.0 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains	0.63	56.0	4.76e-01	100.0%	58.9%
3966472	223.8.1.2 ↗	a+b three layers › Profilin-like › LapD periplasmic domain › LapD periplasmic domain › CHASE8	0.63	53.0	4.56e-01	100.0%	57.6%
4010783	223.8.1.2 ↗	a+b three layers › Profilin-like › LapD periplasmic domain › LapD periplasmic domain › CHASE8	0.63	53.0	5.26e-01	100.0%	88.2%
5049764	223.2.1.0 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like	0.63	51.0	5.08e-01	88.0%	83.5%
3379279	223.1.1.0 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains	0.62	57.0	5.20e-01	100.0%	88.6%
3978824	223.8.1.2 ↗	a+b three layers › Profilin-like › LapD periplasmic domain › LapD periplasmic domain › CHASE8	0.62	52.0	4.49e-01	100.0%	57.6%
3231860	220.1.1.0 ↗	beta barrels › PH domain-like › PH domain-like › PH domain-like	0.62	43.0	4.13e-01	70.4%	78.3%
4512007	223.1.1.58 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains › 2CSK_N	0.60	52.0	4.59e-01	97.2%	64.8%
4971897	223.2.1.0 ↗	a+b three layers › Profilin-like › profilin-like › profilin-like	0.59	49.0	5.23e-01	94.4%	100.0%
3675115	331.3.1.3 ↗	a+b two layers › TBP-like › Bet v1-like › Bet v1-like › START	0.51	45.0	3.45e-01	100.0%	65.3%

D2 high residues 361-523

PDB

Domain cluster: rep: Ig7659_scaffold_8_prodigal-single.1__X__X__00240__D301-446

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02518.32 best	HATPase_c	90.4	1.40e-25	74.9%	97.3%

D3 high residues 538-646

PDB

Domain cluster: rep: DGJ7_scaffold_2_2069_prodigal-single.1__X__X__00303__D2-112

CATH (88)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
6zxbA01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.88	84.0	7.80e-01	100.0%	87.7%
2qzjA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.86	81.0	7.84e-01	100.0%	91.7%
1w25A01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.86	81.0	7.37e-01	100.0%	80.9%
3jteA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.86	81.0	7.67e-01	100.0%	90.5%
3crnA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.86	81.0	7.60e-01	100.0%	86.8%
4d6yA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.86	81.0	7.78e-01	100.0%	94.2%
3i42A00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.85	80.0	7.81e-01	100.0%	94.9%
2vycA01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.85	80.0	7.30e-01	100.0%	92.1%
3gl9A00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.85	80.0	7.75e-01	100.0%	95.8%
6qrjA03	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.85	79.0	7.97e-01	100.0%	98.2%
1dcfA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.85	80.0	7.45e-01	100.0%	86.5%
3t6kA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.85	80.0	7.71e-01	100.0%	93.4%
2wb4B01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.85	80.0	5.79e-01	100.0%	41.1%
4eukA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.85	80.0	7.35e-01	100.0%	94.9%
3lufB02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.85	80.0	7.57e-01	100.0%	91.3%
3grcA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.85	79.0	7.55e-01	100.0%	92.0%
1dc7A00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.85	80.0	7.59e-01	100.0%	91.1%
3hv2A00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.85	80.0	7.32e-01	100.0%	83.1%
5u8kA01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.85	79.0	7.63e-01	100.0%	91.8%
1d5wA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.85	79.0	7.59e-01	100.0%	91.1%
6ontA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.84	79.0	7.65e-01	100.0%	93.4%
7pvaB01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.84	79.0	7.70e-01	100.0%	94.1%
2qsjB00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.84	78.0	7.49e-01	100.0%	87.7%
5dclA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.84	79.0	7.72e-01	100.0%	94.0%
4nicA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.84	79.0	7.70e-01	100.0%	94.9%
1srrC00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.84	78.0	7.57e-01	100.0%	93.4%
3kcnB00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.84	79.0	7.22e-01	100.0%	82.5%
1s8nA01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.84	79.0	7.32e-01	100.0%	84.8%
3hdvB00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.84	78.0	7.44e-01	100.0%	91.3%
2zayA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.84	78.0	7.51e-01	100.0%	92.7%
3cfyA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.84	78.0	7.35e-01	100.0%	86.9%
3ktoA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.84	78.0	7.52e-01	100.0%	94.3%
1r8jB01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.83	76.0	6.76e-01	100.0%	71.1%
3c3mA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.83	72.0	6.87e-01	90.8%	84.6%
2jk1A00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.83	78.0	7.12e-01	100.0%	81.9%
5x5jA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.83	78.0	7.60e-01	100.0%	93.2%
3a0uA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.83	77.0	7.61e-01	100.0%	95.7%
1mb3A00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.83	78.0	7.61e-01	100.0%	93.2%
3h5iA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.83	78.0	7.38e-01	100.0%	90.4%
3rqiA01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.83	77.0	7.27e-01	100.0%	88.2%
3cg4A00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.82	76.0	7.23e-01	100.0%	91.3%
5tqjA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.82	76.0	7.29e-01	100.0%	91.9%
3gt7A00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.81	76.0	7.09e-01	100.0%	86.4%
2b4aA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.81	76.0	7.45e-01	100.0%	94.0%
2rdmA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.80	75.0	7.16e-01	100.0%	91.1%
5t3yA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.80	74.0	7.05e-01	100.0%	92.0%
6xehA01	3.40.50.11230	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.79	72.0	7.24e-01	99.1%	100.0%
3llvA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.77	67.0	6.29e-01	93.6%	92.4%
2mswA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.76	70.0	6.66e-01	100.0%	88.0%
1i1qB00	3.40.50.880	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain	0.75	69.0	5.75e-01	100.0%	96.8%
2kpoA00	3.40.50.11230	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.75	62.0	6.26e-01	100.0%	88.2%
2j48A00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.75	68.0	6.67e-01	100.0%	90.8%
2q5cA01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.74	57.0	5.99e-01	100.0%	89.7%
2l82A00	3.40.50.11230	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.74	67.0	5.87e-01	100.0%	91.4%
3clkB01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.73	63.0	6.08e-01	100.0%	82.8%
4ycsA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.73	67.0	6.42e-01	100.0%	95.1%
1lssA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.73	62.0	5.79e-01	91.7%	91.7%
1efaA02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.72	67.0	6.34e-01	100.0%	88.9%
2cb0A02	3.40.50.10490	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1	0.72	66.0	5.88e-01	100.0%	78.9%
3k9cB01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.72	66.0	6.21e-01	100.0%	85.5%
2vpiA00	3.40.50.880	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain	0.71	65.0	5.41e-01	100.0%	93.0%
3nl6C02	3.40.1190.20	Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase	0.70	64.0	4.67e-01	100.0%	70.4%
2hqbA01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.70	64.0	6.03e-01	100.0%	87.0%
5c8aB02	3.40.50.280	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cobalamin-binding domain	0.70	63.0	6.33e-01	99.1%	100.0%
1c3qA00	3.40.1190.20	Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase	0.70	63.0	4.67e-01	100.0%	70.4%
3a2bA02	3.40.640.10	Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain)	0.69	63.0	4.88e-01	100.0%	58.7%
1j4aD01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.69	63.0	5.89e-01	100.0%	88.9%
3fxaA00	3.40.50.10490	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1	0.69	63.0	5.20e-01	100.0%	69.1%
2qipA00	3.40.50.1010	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease	0.69	59.0	5.16e-01	92.7%	95.0%
3re1A01	3.40.50.10090	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.69	62.0	6.01e-01	100.0%	89.3%
3hbmA01	3.40.50.11190	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.68	61.0	5.58e-01	96.3%	100.0%
1ybhA01	3.40.50.970	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains	0.68	60.0	4.96e-01	97.2%	78.5%
3etnB00	3.40.50.10490	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1	0.68	61.0	5.05e-01	100.0%	67.2%
1xdwA01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.68	61.0	5.71e-01	100.0%	91.0%
2x7jA01	3.40.50.970	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains	0.68	61.0	5.07e-01	100.0%	87.7%
5uqiA00	3.40.50.10490	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1	0.68	61.0	5.11e-01	100.0%	70.2%
4qq8A01	3.40.50.970	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains	0.67	60.0	5.12e-01	100.0%	86.8%
3knzA02	3.40.50.10490	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1	0.67	62.0	5.57e-01	100.0%	80.1%
2cb0A01	3.40.50.10490	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1	0.67	61.0	5.39e-01	100.0%	77.8%
3hwwA01	3.40.50.970	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains	0.66	60.0	4.88e-01	100.0%	85.3%
3i6sA03	3.50.30.30	Alpha Beta › 3-Layer(bba) Sandwich › Glucose Oxidase; domain 1 ›	0.66	49.0	4.69e-01	78.9%	71.5%
1gpjA02	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.65	56.0	5.04e-01	94.5%	81.8%
4kxvA02	3.40.50.970	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains	0.65	57.0	4.79e-01	100.0%	64.4%
1vj0A02	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.65	53.0	4.80e-01	89.0%	87.8%
3bchA01	3.40.50.10490	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1	0.64	57.0	4.79e-01	100.0%	59.4%
2ze3A01	3.20.20.60	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphoenolpyruvate-binding domains	0.63	55.0	4.35e-01	96.3%	97.0%
4toiA01	3.40.50.10490	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1	0.63	56.0	4.80e-01	100.0%	62.4%
4n4pD00	3.20.20.70	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I	0.61	55.0	4.04e-01	100.0%	54.9%

ECOD (100)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3737792	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.88	83.0	7.46e-01	100.0%	83.3%
5018336	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.87	83.0	7.64e-01	100.0%	84.4%
3739788	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.87	83.0	7.31e-01	100.0%	80.5%
5041202	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.87	83.0	8.02e-01	100.0%	95.8%
3301278	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.87	82.0	7.27e-01	100.0%	77.3%
3638719	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.87	82.0	6.92e-01	100.0%	70.6%
3978922	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.87	82.0	7.55e-01	100.0%	85.9%
3741496	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.87	81.0	7.39e-01	100.0%	86.4%
3985284	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.86	81.0	7.62e-01	100.0%	85.4%
165425	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.86	81.0	7.84e-01	100.0%	91.7%
3270813	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.86	81.0	7.11e-01	100.0%	77.9%
3972790	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.86	81.0	7.38e-01	100.0%	80.0%
3512787	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.86	81.0	7.46e-01	100.0%	83.0%
4215872	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.86	81.0	7.46e-01	100.0%	83.0%
3979512	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.86	81.0	7.45e-01	100.0%	83.0%
3270222	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.86	81.0	7.11e-01	100.0%	79.1%
4291338	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.86	81.0	7.35e-01	100.0%	80.7%
3783556	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.86	81.0	6.99e-01	100.0%	76.2%
4253774	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.86	81.0	7.45e-01	100.0%	83.7%
3838886	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.86	81.0	7.55e-01	100.0%	85.4%
4011509	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.86	81.0	6.98e-01	100.0%	78.1%
3599558	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.86	77.0	7.18e-01	100.0%	79.2%
4973021	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.86	80.0	7.21e-01	100.0%	77.9%
4514723	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.85	81.0	7.53e-01	100.0%	86.2%
3728000	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.85	80.0	6.94e-01	100.0%	75.6%
3688246	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.85	80.0	7.30e-01	100.0%	90.6%
3972263	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.85	80.0	7.30e-01	100.0%	83.6%
4225156	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.85	80.0	7.22e-01	100.0%	77.1%
3325480	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.85	80.0	7.02e-01	100.0%	91.0%
3942701	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.85	80.0	7.59e-01	100.0%	89.6%
3386858	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.85	80.0	7.46e-01	100.0%	87.7%
3174413	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.85	80.0	6.61e-01	100.0%	77.8%
3434103	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.85	79.0	7.68e-01	100.0%	95.8%
3981116	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.85	79.0	6.98e-01	100.0%	82.4%
4439830	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.85	80.0	7.70e-01	100.0%	93.3%
3970835	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.85	80.0	7.25e-01	100.0%	83.6%
3264060	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.85	80.0	7.26e-01	100.0%	80.7%
3176483	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.85	80.0	7.36e-01	100.0%	83.0%
3967374	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.85	79.0	6.85e-01	100.0%	72.5%
3254183	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.85	79.0	7.22e-01	100.0%	84.3%
3980630	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.84	79.0	7.42e-01	100.0%	85.4%
4571924	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.84	79.0	6.98e-01	100.0%	82.0%
3464788	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.84	79.0	6.66e-01	100.0%	65.9%
1788971	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.84	79.0	7.72e-01	100.0%	94.0%
3988213	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.84	79.0	7.06e-01	100.0%	76.6%
3268153	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.84	78.0	6.87e-01	100.0%	76.1%
4257953	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.84	79.0	7.15e-01	100.0%	79.3%
4534691	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.84	79.0	7.25e-01	100.0%	87.4%
3258501	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.84	78.0	7.03e-01	100.0%	74.5%
3736804	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.84	79.0	6.82e-01	100.0%	70.0%
4945082	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.84	78.0	7.61e-01	100.0%	97.5%
3267749	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.84	79.0	6.89e-01	100.0%	72.3%
2476521	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.84	78.0	7.30e-01	100.0%	86.3%
3270719	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.83	78.0	6.85e-01	100.0%	76.1%
4927072	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.83	78.0	7.29e-01	100.0%	90.8%
3253433	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.83	78.0	7.19e-01	100.0%	85.9%
4110991	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.83	78.0	7.39e-01	100.0%	88.8%
4980005	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.83	78.0	7.64e-01	100.0%	95.7%
4147569	2007.1.3.16 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › KaiA_N	0.83	78.0	7.06e-01	100.0%	78.6%
3972859	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.83	77.0	7.25e-01	100.0%	84.6%
3968601	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.83	77.0	7.22e-01	100.0%	85.4%
3941477	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.83	77.0	7.25e-01	100.0%	86.2%
4179893	2007.1.3.16 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › KaiA_N	0.82	77.0	6.75e-01	100.0%	73.5%
3966779	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.82	77.0	7.25e-01	100.0%	84.5%
4094395	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.82	77.0	6.99e-01	100.0%	81.4%
3968493	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.82	76.0	7.26e-01	100.0%	87.2%
1893734	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.82	76.0	7.29e-01	100.0%	91.9%
3741468	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.81	75.0	7.31e-01	100.0%	95.0%
10043	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.81	76.0	7.45e-01	100.0%	94.0%
4945241	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.81	76.0	7.20e-01	100.0%	87.2%
3838052	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.81	76.0	7.20e-01	100.0%	88.8%
3279637	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.81	75.0	6.91e-01	100.0%	80.0%
5057081	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.81	75.0	6.84e-01	100.0%	87.1%
4930497	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.81	75.0	7.16e-01	100.0%	92.0%
4127803	2007.1.3.16 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › KaiA_N	0.81	75.0	7.03e-01	100.0%	87.7%
3806357	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.80	75.0	6.81e-01	100.0%	80.0%
3965997	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.80	73.0	7.01e-01	100.0%	90.4%
3255681	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.79	74.0	7.08e-01	100.0%	90.4%
4642945	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.79	72.0	6.77e-01	100.0%	86.9%
3702876	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.77	70.0	6.63e-01	100.0%	92.3%
4400567	2007.1.1.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Class I glutamine amidotransferase-like › GATase	0.76	70.0	5.66e-01	100.0%	93.0%
1497956	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.76	70.0	6.66e-01	100.0%	88.0%
4771626	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.75	62.0	6.26e-01	100.0%	88.2%
3915189	2004.1.1.512 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › URGCP	0.75	68.0	4.93e-01	100.0%	57.6%
4322603	2007.6.1.4 ↗	a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › SIS	0.75	68.0	5.74e-01	100.0%	73.2%
3953826	323.1.1.3 ↗	a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding	0.74	63.0	5.23e-01	94.5%	53.5%
4547621	2007.6.1.4 ↗	a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › SIS	0.73	67.0	5.66e-01	100.0%	71.4%
3964538	2007.6.1.4 ↗	a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › SIS	0.71	65.0	5.22e-01	100.0%	61.0%
3948396	2007.6.1.4 ↗	a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › SIS	0.71	65.0	5.40e-01	100.0%	69.7%
3361648	7574.1.1.0 ↗	a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding)	0.71	55.0	4.43e-01	82.6%	82.4%
2391064	323.1.1.3 ↗	a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding	0.71	58.0	4.91e-01	97.2%	54.3%
3608927	2007.6.1.4 ↗	a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › SIS	0.70	64.0	4.33e-01	100.0%	33.2%
4464684	2007.1.2.5 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Bmp	0.70	63.0	4.49e-01	100.0%	78.4%
3289835	2007.1.2.5 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Bmp	0.69	62.0	4.43e-01	100.0%	79.1%
3954449	7574.1.1.7 ↗	a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_N	0.69	62.0	5.27e-01	100.0%	87.2%
3955326	7574.1.1.7 ↗	a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_N	0.67	60.0	5.13e-01	100.0%	91.1%
3838552	2006.1.3.12 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › DUF3226	0.65	59.0	5.10e-01	100.0%	100.0%
3642000	7512.1.1.0 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase	0.64	57.0	4.38e-01	100.0%	61.6%
4444459	2003.1.1.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains	0.64	54.0	4.11e-01	94.5%	49.4%
5073176	2003.1.1.37 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › 2-Hacid_dh_C	0.63	52.0	4.26e-01	91.7%	70.0%

D4 high residues 664-789

PDB

Domain cluster: rep: DGJ7_scaffold_2_2069_prodigal-single.1__X__X__00303__D2-112

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00072.31 best	Response_reg	86.5	1.90e-24	97.6%	99.1%

CATH (95)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
6qrjA03	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.96	81.0	8.77e-01	100.0%	100.0%
1oxkB00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.96	90.0	8.96e-01	100.0%	94.5%
3m6mD00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.93	83.0	8.63e-01	100.0%	98.3%
1ab5A00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.93	84.0	8.46e-01	100.0%	93.6%
1w25A01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.93	83.0	7.94e-01	100.0%	82.3%
1mb3A00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.93	79.0	8.20e-01	100.0%	94.0%
3gl9A00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.93	83.0	8.51e-01	100.0%	96.7%
2qzjA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.93	80.0	8.25e-01	100.0%	93.4%
3hzhA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.93	83.0	8.13e-01	100.0%	87.3%
6ontA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.93	81.0	8.29e-01	100.0%	94.2%
3t6kA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.92	82.0	8.40e-01	100.0%	95.1%
2wb4B01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.92	82.0	6.09e-01	100.0%	42.2%
6zxbA01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.92	82.0	8.09e-01	100.0%	89.2%
2pl1A00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.91	80.0	8.20e-01	100.0%	95.0%
7lzaA01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.91	80.0	8.26e-01	100.0%	96.6%
1dcfA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.91	82.0	8.07e-01	100.0%	88.0%
3cfyA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.91	80.0	7.90e-01	100.0%	87.7%
4d6yA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.91	81.0	8.31e-01	100.0%	95.9%
3a0uA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.91	78.0	8.20e-01	100.0%	97.4%
3jteA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.91	81.0	8.12e-01	100.0%	92.1%
3crnA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.91	79.0	7.90e-01	100.0%	88.4%
3c3mA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.91	73.0	7.44e-01	90.5%	84.6%
4nicA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.91	78.0	8.15e-01	100.0%	96.6%
1p2fA01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.90	77.0	7.93e-01	100.0%	93.3%
3lufB02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.90	81.0	8.15e-01	100.0%	92.9%
5lnmA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.90	87.0	8.09e-01	100.0%	87.3%
7pvaB01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.90	79.0	8.11e-01	100.0%	95.8%
2zayA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.90	80.0	8.10e-01	100.0%	94.3%
2jb9B00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.90	80.0	8.16e-01	100.0%	95.1%
1d5wA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.90	78.0	7.92e-01	100.0%	92.7%
3eodA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.89	73.0	7.67e-01	100.0%	93.0%
3hdvB00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.89	79.0	7.94e-01	100.0%	92.1%
3eulB00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.89	78.0	7.95e-01	100.0%	93.5%
3grcA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.89	79.0	8.01e-01	100.0%	93.6%
2v0nA02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.89	77.0	7.27e-01	100.0%	78.1%
4gvpA01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.89	78.0	6.45e-01	100.0%	56.3%
2qxyA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.89	76.0	7.86e-01	100.0%	95.0%
3h5iA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.88	78.0	7.89e-01	100.0%	92.0%
3breB01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.88	79.0	7.50e-01	100.0%	81.8%
5tqjA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.88	77.0	7.81e-01	100.0%	92.7%
3gt7A00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.88	78.0	7.69e-01	100.0%	87.9%
4q7eA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.88	76.0	7.69e-01	100.0%	91.2%
3hdgA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.88	76.0	7.74e-01	100.0%	91.9%
4eukA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.88	85.0	8.28e-01	100.0%	96.3%
3lteD00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.88	77.0	7.80e-01	100.0%	93.5%
3hv2A00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.88	77.0	7.48e-01	100.0%	84.6%
3ilhA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.88	83.0	8.20e-01	100.0%	94.7%
5u8kA01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.87	76.0	7.74e-01	100.0%	93.4%
1srrC00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.87	75.0	7.72e-01	100.0%	94.2%
2gkgA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.87	77.0	7.82e-01	100.0%	95.1%
3rqiA01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.87	76.0	7.58e-01	100.0%	90.6%
2qr3A00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.87	75.0	7.69e-01	100.0%	94.2%
3b2nA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.86	76.0	7.82e-01	100.0%	96.7%
3cnbA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.86	77.0	7.79e-01	100.0%	95.2%
2hqoA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.86	73.0	7.56e-01	100.0%	94.1%
2b4aA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.86	72.0	7.53e-01	100.0%	94.8%
2rdmA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.86	74.0	7.53e-01	100.0%	91.9%
6qrjA02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.86	70.0	7.32e-01	100.0%	92.2%
3cg4A00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.85	76.0	7.61e-01	100.0%	92.1%
4xltA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.85	79.0	7.89e-01	100.0%	96.1%
3ktoA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.85	75.0	7.65e-01	100.0%	95.1%
1r8jB01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.85	71.0	6.63e-01	100.0%	73.2%
4dadA01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.85	75.0	7.54e-01	100.0%	91.4%
5o8zB01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.84	75.0	7.20e-01	100.0%	84.4%
1a04A01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.83	76.0	7.69e-01	100.0%	97.6%
4zylB00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.83	78.0	7.46e-01	100.0%	91.7%
2qvgA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.83	77.0	7.72e-01	100.0%	96.9%
3lufB01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.82	73.0	7.47e-01	100.0%	97.5%
4ldaB00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.82	71.0	7.17e-01	100.0%	91.3%
2j48A00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.82	68.0	7.01e-01	100.0%	92.4%
1k68A00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.82	77.0	7.41e-01	100.0%	92.1%
3hebA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.81	77.0	7.35e-01	100.0%	95.1%
3luaA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.81	73.0	7.34e-01	100.0%	95.2%
4wxmB00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.81	71.0	7.07e-01	100.0%	89.9%
1z0sA01	3.40.50.10330	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Probable inorganic polyphosphate/atp-NAD kinase; domain 1	0.81	59.0	5.95e-01	100.0%	75.8%
3khtA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.81	74.0	7.32e-01	100.0%	93.2%
2mswA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.80	68.0	6.84e-01	100.0%	89.6%
5t3yA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.80	69.0	6.98e-01	100.0%	92.8%
1k66A00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.80	75.0	7.03e-01	100.0%	88.6%
4myrC00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.79	70.0	7.09e-01	100.0%	95.2%
3snkA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.78	68.0	6.98e-01	100.0%	96.6%
6xehA01	3.40.50.11230	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.78	65.0	6.84e-01	98.4%	100.0%
4ml3D00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.77	73.0	7.19e-01	100.0%	95.4%
2kpoA00	3.40.50.11230	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.74	56.0	5.97e-01	100.0%	90.0%
1eucB03	3.40.50.261	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Succinyl-CoA synthetase domains	0.70	65.0	6.16e-01	100.0%	87.7%
2l82A00	3.40.50.11230	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.68	61.0	5.65e-01	100.0%	97.5%
3qqwC01	3.20.20.60	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphoenolpyruvate-binding domains	0.68	54.0	4.23e-01	84.9%	91.6%
4b8wB01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.66	60.0	5.10e-01	100.0%	84.3%
3kzpA00	3.20.20.450	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › EAL domain	0.63	49.0	4.00e-01	81.7%	90.9%
3tovA02	3.40.50.2000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B;	0.62	57.0	4.99e-01	100.0%	85.4%
4ilkA02	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.61	51.0	4.98e-01	88.1%	89.6%
3k13A00	3.20.20.20	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Dihydropteroate synthase-like	0.61	49.0	3.80e-01	87.3%	81.8%
1exbA00	3.20.20.100	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › NADP-dependent oxidoreductase domain	0.59	53.0	3.93e-01	98.4%	81.9%
3e8mA00	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.59	53.0	4.91e-01	99.2%	90.9%
3bleA00	3.20.20.70	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I	0.58	53.0	3.99e-01	100.0%	71.7%

ECOD (100)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3971966	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.98	90.0	8.65e-01	100.0%	85.0%
3192551	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.98	91.0	6.56e-01	100.0%	40.7%
3270813	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.97	92.0	8.40e-01	100.0%	79.2%
3254183	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.97	90.0	8.58e-01	100.0%	85.7%
4019112	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.97	87.0	8.30e-01	100.0%	82.9%
3251565	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.96	89.0	8.70e-01	100.0%	88.9%
3184621	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.96	89.0	8.70e-01	100.0%	88.9%
3741496	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.96	91.0	8.73e-01	100.0%	87.9%
3784364	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.96	90.0	7.42e-01	100.0%	60.5%
3737792	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.96	90.0	8.53e-01	100.0%	84.7%
3304411	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.96	87.0	8.16e-01	100.0%	79.7%
4552753	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.96	86.0	8.50e-01	100.0%	89.2%
3782506	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.95	93.0	8.74e-01	100.0%	86.9%
3972263	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.95	87.0	8.38e-01	100.0%	85.0%
3739788	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.95	90.0	8.35e-01	100.0%	81.9%
3984609	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.95	85.0	7.91e-01	100.0%	77.3%
3322262	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.95	92.0	8.34e-01	100.0%	90.6%
3970835	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.95	87.0	8.32e-01	100.0%	85.0%
3264062	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.95	89.0	8.83e-01	100.0%	93.8%
3257809	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.95	90.0	8.52e-01	100.0%	85.5%
4996850	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.94	87.0	8.79e-01	100.0%	96.0%
5062924	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.94	83.0	7.40e-01	100.0%	69.1%
3728000	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.94	89.0	8.08e-01	100.0%	76.9%
3688246	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.94	89.0	8.60e-01	98.4%	90.6%
4448569	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.94	82.0	8.31e-01	100.0%	91.2%
3270222	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.94	89.0	8.19e-01	100.0%	80.4%
5020415	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.94	83.0	8.08e-01	100.0%	85.2%
3973233	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.94	86.0	8.49e-01	100.0%	91.5%
5020414	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.93	83.0	8.58e-01	100.0%	96.7%
3978922	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.93	85.0	8.25e-01	100.0%	87.4%
3966963	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.93	83.0	8.53e-01	100.0%	96.7%
3970523	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.93	83.0	8.50e-01	100.0%	96.7%
3330118	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.93	81.0	8.05e-01	100.0%	87.7%
3783556	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.93	89.0	8.08e-01	100.0%	78.1%
3663935	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.93	86.0	8.51e-01	100.0%	93.0%
4474529	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.93	83.0	8.26e-01	100.0%	90.0%
5018153	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.93	82.0	7.57e-01	100.0%	74.8%
None	—		0.93	83.0	7.34e-01	100.0%	68.8%
4130633	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.93	83.0	7.18e-01	100.0%	65.0%
3972637	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.92	82.0	8.16e-01	100.0%	89.2%
None	—		0.92	83.0	7.74e-01	100.0%	78.5%
3434103	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.92	82.0	8.45e-01	100.0%	96.7%
3694142	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.92	89.0	8.17e-01	100.0%	91.0%
3838332	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.92	83.0	8.00e-01	100.0%	84.3%
3721185	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.92	89.0	8.56e-01	100.0%	90.0%
3732190	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.92	87.0	8.34e-01	100.0%	88.6%
3683813	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.92	89.0	8.16e-01	100.0%	94.8%
5052869	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.92	83.0	8.40e-01	100.0%	95.9%
4927745	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.91	85.0	8.60e-01	100.0%	97.6%
3691104	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.91	86.0	8.43e-01	100.0%	91.9%
3325480	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.91	89.0	8.12e-01	100.0%	92.3%
3838886	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.91	79.0	7.83e-01	100.0%	86.9%
149841	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.91	82.0	8.09e-01	100.0%	90.0%
3832372	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.91	88.0	8.18e-01	100.0%	87.3%
4269582	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.91	81.0	8.01e-01	100.0%	89.2%
3388140	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.91	78.0	7.74e-01	100.0%	86.2%
4939118	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.91	79.0	8.18e-01	100.0%	95.0%
3973061	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.91	81.0	7.99e-01	100.0%	89.2%
3966620	304.48.1.0 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like	0.91	82.0	5.79e-01	100.0%	36.0%
3272960	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.91	88.0	8.34e-01	100.0%	88.9%
3734723	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.91	88.0	8.17e-01	100.0%	84.7%
4443047	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.91	80.0	8.01e-01	100.0%	89.9%
5049630	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.91	82.0	7.72e-01	100.0%	81.4%
140201	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.91	77.0	8.01e-01	100.0%	94.9%
4336279	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.91	80.0	7.59e-01	100.0%	80.0%
385830	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.90	81.0	7.85e-01	100.0%	85.4%
4046390	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.90	80.0	7.82e-01	100.0%	85.9%
3802816	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.90	79.0	7.45e-01	100.0%	78.6%
3968444	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.90	81.0	7.94e-01	100.0%	87.4%
3181115	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.90	86.0	7.84e-01	100.0%	81.2%
4247760	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.90	81.0	7.78e-01	100.0%	84.3%
3460763	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.89	80.0	7.67e-01	100.0%	83.6%
3973985	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.89	85.0	8.18e-01	100.0%	89.3%
10041	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.89	78.0	7.18e-01	100.0%	74.5%
4623576	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.89	85.0	8.19e-01	100.0%	90.6%
4238346	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.89	80.0	7.36e-01	100.0%	76.1%
5019016	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.89	78.0	8.05e-01	100.0%	96.7%
138404	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.89	82.0	8.29e-01	98.4%	97.6%
3424210	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.89	85.0	8.06e-01	100.0%	89.7%
234921	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.88	85.0	8.28e-01	100.0%	96.3%
3386257	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.88	84.0	7.95e-01	100.0%	86.9%
136089	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.88	83.0	8.22e-01	100.0%	95.5%
4950558	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.88	80.0	7.64e-01	100.0%	85.0%
3973957	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.87	80.0	7.84e-01	100.0%	89.6%
4213665	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.87	71.0	6.87e-01	100.0%	76.4%
3380668	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.87	83.0	7.77e-01	100.0%	91.3%
4980713	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.85	81.0	7.86e-01	99.2%	99.3%
1095677	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.85	76.0	7.37e-01	100.0%	86.1%
3834428	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.85	81.0	6.94e-01	100.0%	73.5%
3662749	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.84	59.0	6.75e-01	100.0%	95.8%
3377324	2007.1.3.33 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Receiver_CRE1	0.83	79.0	7.27e-01	100.0%	81.9%
4980667	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.83	79.0	7.35e-01	100.0%	83.3%
4984338	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.83	76.0	7.45e-01	100.0%	89.6%
1697439	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.83	78.0	7.46e-01	100.0%	91.7%
165361	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.83	77.0	7.69e-01	100.0%	96.1%
134932	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.81	77.0	7.40e-01	100.0%	96.4%
10035	2007.1.3.1 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg	0.80	75.0	7.03e-01	100.0%	88.6%
4330223	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.79	74.0	7.16e-01	100.0%	97.1%
3366498	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.76	71.0	6.60e-01	100.0%	82.6%
4957763	2007.3.1.6 ↗	a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains › Ligase_CoA_2	0.66	60.0	5.50e-01	100.0%	90.2%

D5 high residues 817-929

PDB

Domain cluster: rep: S2_012_000_R2_scaffold_0_prodigal-single.1__X__X__01100__D210-307

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01627.29 best	Hpt	52.0	9.10e-14	83.2%	86.9%

CATH (44)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3iqtA01	1.20.120.160	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain	0.92	82.0	8.18e-01	100.0%	91.2%
1i5nB00	1.20.120.160	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain	0.89	75.0	7.29e-01	88.5%	82.3%
7c1iA01	1.20.120.160	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain	0.89	73.0	7.74e-01	97.3%	97.0%
3kyiA00	1.20.120.160	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain	0.87	72.0	6.90e-01	86.7%	82.8%
1tqgA00	1.20.120.160	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain	0.87	71.0	7.39e-01	85.8%	100.0%
4xpwA00	1.20.120.50	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like	0.85	66.0	6.23e-01	80.5%	89.3%
1c02A00	1.20.120.160	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain	0.84	79.0	6.85e-01	100.0%	91.0%
3agtA00	1.20.120.50	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like	0.83	64.0	6.02e-01	80.5%	88.0%
1sr2A00	1.20.120.160	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain	0.83	64.0	6.40e-01	95.6%	78.4%
2a0bA00	1.20.120.160	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain	0.82	73.0	7.20e-01	100.0%	89.8%
1wn0A00	1.20.120.160	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain	0.80	76.0	7.20e-01	100.0%	91.6%
2yfaB01	1.20.1440.210	Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) ›	0.80	65.0	6.43e-01	85.8%	100.0%
1sziA02	1.20.120.340	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS	0.77	65.0	6.13e-01	91.2%	94.2%
1nzeA00	1.20.120.290	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle	0.76	68.0	6.83e-01	92.9%	96.4%
3fajA00	1.20.120.950	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein DUF5062	0.75	59.0	6.19e-01	83.2%	100.0%
3dzaA01	1.20.120.1940	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YfdX protein domain	0.73	55.0	5.43e-01	77.9%	88.0%
7p3rA01	1.20.1170.10	Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; ›	0.72	63.0	4.51e-01	94.7%	98.8%
1b68A00	1.20.120.20	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein	0.72	58.0	5.47e-01	86.7%	95.7%
3zsuA00	1.20.120.290	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle	0.72	65.0	6.39e-01	96.5%	96.6%
2hsbA00	1.20.120.330	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2	0.72	58.0	5.57e-01	85.8%	96.8%
1xg2B00	1.20.140.40	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein	0.71	51.0	4.58e-01	74.3%	64.2%
3dyjA02	1.20.1420.10	Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain	0.71	63.0	5.74e-01	98.2%	85.4%
4fx5A03	1.20.120.1690	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) ›	0.70	54.0	5.76e-01	89.4%	92.0%
4i1mB01	1.20.120.1700	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) ›	0.70	56.0	5.34e-01	85.0%	92.2%
2pmsC00	6.10.140.920	Special › Helix non-globular › Helix Hairpins ›	0.70	42.0	4.27e-01	91.2%	61.5%
3iqcA00	1.20.120.340	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS	0.69	62.0	6.08e-01	100.0%	90.8%
4cbeA00	1.20.120.1640	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) ›	0.67	53.0	4.38e-01	85.8%	100.0%
3c18A02	1.20.120.330	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2	0.67	55.0	5.46e-01	90.3%	96.6%
1orjD00	1.20.120.340	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS	0.67	60.0	5.86e-01	100.0%	97.6%
4ciuA02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.65	46.0	3.79e-01	72.6%	84.4%
5dn6J00	1.20.20.10	Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C	0.65	37.0	4.41e-01	90.3%	85.1%
1t72A01	1.20.58.220	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2	0.62	42.0	4.21e-01	100.0%	66.7%
1cnt200	1.20.1250.10	Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; ›	0.62	53.0	5.03e-01	91.2%	93.1%
1vctA01	1.20.58.220	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2	0.62	44.0	4.50e-01	74.3%	97.2%
4mh6A00	1.10.287.1700	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.61	41.0	3.63e-01	91.2%	49.1%
1kt1A03	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.60	45.0	4.04e-01	78.8%	60.8%
1e7pC00	1.20.1300.10	Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit	0.60	48.0	3.80e-01	89.4%	73.6%
1sumB01	1.20.58.220	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2	0.58	40.0	4.14e-01	70.8%	94.4%
6gpxB00	1.20.1070.10	Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins	0.58	51.0	3.99e-01	100.0%	80.6%
3cskA02	3.30.540.30	Alpha Beta › 2-Layer Sandwich › Fructose-1,6-Bisphosphatase; Chain A, domain 1 ›	0.55	44.0	3.96e-01	86.7%	69.1%
3l8rA00	1.20.58.80	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit	0.55	40.0	4.23e-01	77.9%	100.0%
5jrcA00	1.20.58.2140	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.54	43.0	3.68e-01	85.8%	55.9%
6xj1A01	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.54	37.0	2.86e-01	91.2%	32.2%
1yw0A00	1.20.58.480	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.50	42.0	3.33e-01	92.0%	79.0%

ECOD (66)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4620533	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.94	82.0	7.87e-01	100.0%	81.6%
3971953	601.3.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain	0.92	81.0	7.80e-01	100.0%	82.4%
136505	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.92	82.0	7.91e-01	100.0%	84.6%
3947493	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.92	81.0	8.30e-01	100.0%	94.5%
3256631	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.91	79.0	7.79e-01	100.0%	85.8%
3982476	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.90	80.0	7.81e-01	100.0%	86.7%
4469856	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.90	75.0	7.24e-01	86.7%	84.8%
5007109	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.90	73.0	6.97e-01	85.0%	78.5%
3386367	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.89	76.0	7.11e-01	89.4%	80.7%
5013248	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.89	73.0	7.07e-01	85.8%	88.0%
54463	601.3.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain	0.89	75.0	7.29e-01	88.5%	82.3%
2697024	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.88	77.0	7.67e-01	100.0%	89.6%
3973571	601.3.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain	0.88	77.0	7.67e-01	100.0%	89.6%
4464661	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.88	75.0	7.03e-01	89.4%	79.3%
5020418	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.88	75.0	6.90e-01	89.4%	77.9%
4446522	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.88	75.0	6.95e-01	90.3%	78.6%
4340169	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.88	77.0	7.50e-01	100.0%	85.4%
3943886	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.87	76.0	7.62e-01	100.0%	90.4%
138117	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.87	72.0	6.90e-01	86.7%	82.8%
5040017	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.86	77.0	7.86e-01	100.0%	96.4%
3974194	601.3.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain	0.86	71.0	6.64e-01	86.7%	77.8%
3740639	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.85	80.0	7.30e-01	100.0%	84.1%
4009218	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.85	69.0	7.02e-01	100.0%	87.2%
4949044	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.85	66.0	6.68e-01	81.4%	87.6%
3973977	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.85	79.0	7.66e-01	100.0%	89.6%
1147365	601.14.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin	0.85	66.0	6.17e-01	80.5%	87.3%
3971675	601.3.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain	0.85	76.0	7.19e-01	98.2%	81.5%
3971690	601.3.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain	0.84	81.0	7.76e-01	100.0%	90.4%
4556629	601.18.1.26 ↗	alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › PF30890	0.84	60.0	6.68e-01	84.1%	92.2%
3974600	601.3.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain	0.83	77.0	7.34e-01	97.3%	84.6%
4387475	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.83	73.0	7.05e-01	100.0%	84.0%
3796225	192.29.1.0 ↗	alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding)	0.83	72.0	6.92e-01	91.2%	96.8%
2758046	3684.1.1.0 ↗	alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like	0.83	66.0	6.40e-01	84.1%	100.0%
3967556	601.3.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain	0.83	65.0	6.89e-01	82.3%	97.0%
4502437	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.83	68.0	6.71e-01	86.7%	85.8%
3971921	601.3.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain	0.83	74.0	7.45e-01	100.0%	93.9%
3967034	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.83	75.0	7.46e-01	100.0%	93.9%
143387	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.83	69.0	6.97e-01	88.5%	94.7%
4927006	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.82	68.0	6.79e-01	86.7%	90.4%
3968542	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.82	72.0	7.21e-01	100.0%	91.3%
2392079	109.3.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat	0.82	73.0	5.43e-01	93.8%	47.1%
4995268	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.82	67.0	6.42e-01	85.8%	75.4%
3969575	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.82	72.0	6.70e-01	92.0%	80.7%
2833103	601.3.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain	0.82	69.0	7.17e-01	88.5%	100.0%
3369650	601.3.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain	0.82	78.0	6.95e-01	100.0%	79.3%
3967074	601.3.1.15 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › PF27543	0.81	67.0	6.56e-01	85.8%	86.7%
4886833	601.48.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › vWA2 C-terminal domain › vWA2 C-terminal domain › ArnB_C	0.81	61.0	6.57e-01	82.3%	91.8%
3974602	601.3.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain	0.81	75.0	6.90e-01	98.2%	80.7%
3311111	601.3.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain	0.80	76.0	6.92e-01	100.0%	83.2%
4881515	3684.1.1.0 ↗	alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like	0.80	69.0	6.66e-01	91.2%	90.5%
3346328	601.3.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain	0.79	74.0	6.75e-01	100.0%	84.1%
5020411	601.4.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains	0.77	65.0	5.86e-01	89.4%	84.0%
3611706	601.3.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain	0.77	58.0	5.56e-01	89.4%	68.5%
3970726	601.3.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain	0.77	67.0	6.21e-01	98.2%	75.0%
3967073	601.3.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain	0.77	64.0	6.32e-01	89.4%	87.5%
3972132	601.33.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain	0.76	63.0	5.82e-01	89.4%	80.0%
3974601	601.3.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain	0.76	68.0	6.89e-01	96.5%	98.2%
4927880	601.16.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase	0.73	64.0	6.41e-01	93.8%	100.0%
3373349	601.18.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › PsbQ	0.72	63.0	6.10e-01	92.9%	87.2%
4988730	601.3.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt	0.72	59.0	5.71e-01	88.5%	79.2%
150632	601.18.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › PsbQ	0.72	65.0	6.39e-01	96.5%	96.6%
3267227	3711.1.1.60 ↗	alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › bZIP_2	0.62	52.0	3.83e-01	92.0%	74.8%
3628737	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.57	38.0	2.98e-01	91.2%	32.3%
3374717	109.4.1.2596 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2, NatA_aux_su, PF31234	0.57	41.0	3.19e-01	73.5%	36.3%
3956543	3352.1.1.14 ↗	alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › Arabinose_trans	0.54	46.0	3.12e-01	96.5%	60.0%
3553581	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.51	44.0	3.41e-01	93.8%	54.6%

D6 medium residues 5-61

PDB

Domain cluster: representative

D7 medium residues 170-237

PDB

Domain cluster: representative

CATH (3)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4cq4B00	6.10.340.10	Special › Helix non-globular › hypothetical protein mp506/mpn330, domain 1 ›	0.75	65.0	5.68e-01	97.1%	66.7%
3lnrA00	1.20.120.1530	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) ›	0.73	65.0	4.90e-01	100.0%	74.4%
1oj6A00	1.10.490.10	Mainly Alpha › Orthogonal Bundle › Globin-like › Globins	0.55	38.0	2.95e-01	70.6%	52.4%

ECOD (3)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3244833	3914.1.1.2 ↗	alpha bundles › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › Anoctamin,Anoct_dimer	0.70	56.0	3.21e-01	88.2%	16.6%
3286525	4168.1.1.1 ↗	alpha duplicates or obligate multimers › HAMP domain › HAMP domain › HAMP domain › HAMP	0.64	47.0	4.52e-01	80.9%	85.0%
3996794	109.25.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A	0.60	40.0	3.64e-01	70.6%	77.9%

D8 medium residues 238-360

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00512.32 best	HisKA	80.4	1.10e-22	54.5%	100.0%

CATH (20)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2gl2B00	1.10.287.1700	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.83	61.0	6.44e-01	75.6%	93.6%
4mh6A00	1.10.287.1700	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.81	65.0	5.90e-01	83.7%	73.0%
2ch7A00	1.10.287.950	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein	0.77	68.0	5.03e-01	95.9%	84.5%
4ke2A00	6.10.140.1860	Special › Helix non-globular › Helix Hairpins ›	0.76	64.0	5.47e-01	91.1%	69.4%
1qu7A00	1.10.287.950	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein	0.75	64.0	5.19e-01	91.9%	57.3%
3g67A00	1.10.287.950	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein	0.74	63.0	5.17e-01	94.3%	52.1%
2q12A00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.73	60.0	4.77e-01	87.8%	44.2%
2rd0B00	1.10.287.1490	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.73	57.0	5.53e-01	84.6%	73.4%
1u7lA02	1.20.1460.10	Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2	0.72	52.0	4.55e-01	74.8%	84.2%
2efkA01	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.72	60.0	4.68e-01	91.1%	42.4%
3vkgA12	1.10.287.2610	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.70	61.0	5.12e-01	95.9%	79.1%
4wpeA00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.70	61.0	4.72e-01	96.7%	42.9%
3na7A00	1.10.287.1490	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.68	61.0	4.85e-01	96.7%	49.8%
3vkgB06	1.20.920.20	Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A ›	0.68	60.0	4.75e-01	95.9%	83.3%
1t98A02	1.20.58.590	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain	0.68	47.0	4.31e-01	71.5%	72.4%
6vq6G02	1.20.1460.10	Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2	0.64	48.0	4.16e-01	76.4%	83.2%
2b5uA02	1.10.287.620	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins	0.64	50.0	4.57e-01	82.9%	70.2%
3pwxA01	1.20.1330.10	Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain	0.62	51.0	4.48e-01	90.2%	59.8%
3u0cA00	1.20.120.330	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2	0.61	52.0	4.89e-01	95.1%	77.5%
5y06A01	1.10.287.1490	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.58	50.0	4.16e-01	95.9%	54.1%

ECOD (64)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3339561	605.1.1.1 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA	0.91	65.0	7.23e-01	73.2%	89.0%
3971224	223.1.1.0 ↗	a+b three layers › Profilin-like › sensor domains › sensor domains	0.86	63.0	5.03e-01	76.4%	41.3%
3718629	3755.2.1.0 ↗	alpha bundles › YscO-like › Flagellar FliJ protein › Flagellar FliJ protein	0.84	75.0	5.75e-01	94.3%	65.4%
3257797	605.1.1.1 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA	0.83	77.0	6.05e-01	98.4%	91.9%
4001189	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.82	64.0	4.21e-01	81.3%	36.5%
5005097	3710.1.1.0 ↗	alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain	0.81	61.0	5.98e-01	78.0%	72.9%
3302413	605.1.1.1 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA	0.81	73.0	7.30e-01	97.6%	96.0%
3976215	105.2.1.0 ↗	alpha duplicates or obligate multimers › HLH-like › Dimerization domain in LRIM1/APL1C › Dimerization domain in LRIM1/APL1C	0.80	62.0	5.71e-01	81.3%	63.9%
4345467	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.80	61.0	4.02e-01	78.9%	28.3%
3829344	3922.1.1.295 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DUF7653	0.79	56.0	4.62e-01	72.4%	42.4%
3731612	2004.1.1.567 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_23	0.79	70.0	4.26e-01	95.9%	17.3%
4549103	3755.4.1.54 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PF30340	0.79	65.0	4.52e-01	87.0%	79.2%
3488978	4177.1.1.0 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like	0.79	71.0	5.32e-01	96.7%	41.0%
3488631	4177.1.1.0 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like	0.79	69.0	5.22e-01	94.3%	41.8%
3563649	148.1.3.254 ↗	alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › KIF21A_4th	0.78	54.0	3.76e-01	71.5%	23.9%
3875112	3291.1.1.0 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related	0.78	66.0	4.71e-01	89.4%	66.5%
3711643	3939.1.1.0 ↗	alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain	0.78	69.0	5.33e-01	95.9%	44.5%
3294656	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.77	68.0	4.80e-01	95.9%	86.6%
3385717	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.77	64.0	5.77e-01	92.7%	65.3%
3967398	3755.1.1.1 ↗	alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › YscO	0.76	56.0	5.26e-01	77.2%	62.7%
4219808	192.1.1.0 ↗	alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain	0.76	67.0	4.74e-01	94.3%	41.4%
3189020	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.76	56.0	3.58e-01	75.6%	57.0%
3704105	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.76	62.0	5.69e-01	95.9%	67.5%
3968781	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.75	63.0	5.94e-01	88.6%	75.2%
3785314	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.75	66.0	5.21e-01	95.1%	60.0%
3213281	4177.1.1.1 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH	0.75	67.0	5.10e-01	96.7%	43.7%
3678791	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.74	61.0	5.05e-01	94.3%	51.0%
3908810	4177.1.1.1 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH	0.74	65.0	4.86e-01	94.3%	40.0%
3172328	4177.1.1.97 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › PF30147	0.74	54.0	4.18e-01	78.0%	35.8%
5007101	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.74	64.0	4.57e-01	94.3%	54.2%
5032566	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.73	59.0	3.97e-01	84.6%	61.1%
3576467	4177.1.1.1 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH	0.73	65.0	4.82e-01	96.7%	39.0%
3169381	874.1.1.0 ↗	a+b duplicates or obligate multimers › Smc hinge domain › Smc hinge domain › Smc hinge domain	0.72	58.0	4.89e-01	85.4%	82.4%
3704884	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.72	62.0	5.11e-01	95.1%	64.9%
3691415	2004.1.1.748 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_15, AAA_23, SbcC_Walker_B	0.72	57.0	3.66e-01	83.7%	24.8%
3935064	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.72	63.0	4.74e-01	95.9%	72.9%
3702347	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.71	57.0	5.03e-01	84.6%	78.9%
3213527	4177.1.1.1 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH	0.71	62.0	4.76e-01	96.7%	42.8%
4321938	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.70	62.0	5.62e-01	96.7%	78.2%
3620978	2003.1.2.18 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain	0.70	59.0	4.33e-01	90.2%	37.2%
4994917	3834.1.1.25 ↗	alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain › DUF7121	0.70	61.0	4.88e-01	95.9%	58.8%
3611166	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.70	61.0	5.20e-01	95.9%	75.5%
3210422	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.70	56.0	3.71e-01	86.2%	66.7%
3949412	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.70	58.0	5.08e-01	95.9%	60.0%
4045132	192.8.1.0 ↗	alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain	0.69	48.0	5.04e-01	74.0%	80.0%
3251434	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.69	56.0	4.88e-01	86.2%	60.6%
3456370	192.2.1.0 ↗	alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin	0.69	59.0	5.52e-01	95.1%	75.5%
3779599	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.68	62.0	4.15e-01	100.0%	51.7%
3579748	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.68	56.0	5.11e-01	91.9%	65.9%
5042955	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.68	50.0	3.21e-01	77.2%	16.2%
4210642	3755.1.1.12 ↗	alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › CheZ	0.67	48.0	4.72e-01	73.2%	78.5%
4955963	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.67	57.0	4.91e-01	95.1%	64.0%
3920552	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.66	54.0	4.58e-01	90.2%	87.6%
5010596	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.65	56.0	4.65e-01	95.1%	53.2%
3506760	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.64	45.0	4.45e-01	71.5%	86.9%
5047075	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.64	56.0	4.10e-01	95.9%	56.2%
4985493	3834.1.1.0 ↗	alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain	0.64	47.0	3.70e-01	75.6%	59.2%
4392204	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.64	55.0	4.62e-01	95.9%	53.6%
3520603	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.64	53.0	3.39e-01	90.2%	72.2%
3712647	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.64	52.0	3.88e-01	88.6%	39.4%
5056871	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.63	54.0	4.09e-01	95.1%	40.3%
3496957	2003.1.2.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain	0.63	55.0	3.55e-01	95.9%	39.8%
4086306	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.63	51.0	4.28e-01	90.2%	49.3%
5072280	4177.1.1.0 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like	0.61	54.0	4.49e-01	95.9%	76.3%