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CAKLQH020000016.1__CAH1089167.1__SAMEA5780036_02438__00007
Bact-VirCAKLQH020000016.1__CAH1089167.1__SAMEA5780036_02438__00007
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 28-146
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00854.28 best | PTR2 | 41.2 | 1.40e-10 | 48.7% | 15.6% |
CATH (33)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4w6vA00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.99 | 97.0 | 6.08e-01 | 100.0% | 24.6% |
| 6gs4A00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.95 | 87.0 | 5.55e-01 | 100.0% | 24.1% |
| 4oh3A00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.89 | 85.0 | 5.36e-01 | 100.0% | 26.8% |
| 7d5qA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.87 | 77.0 | 6.52e-01 | 100.0% | 61.0% |
| 3o7qA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.85 | 75.0 | 6.29e-01 | 100.0% | 58.3% |
| 1pw4A02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.84 | 77.0 | 6.24e-01 | 100.0% | 54.7% |
| 8ex5A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.83 | 73.0 | 6.16e-01 | 100.0% | 58.6% |
| 3o7pA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.83 | 71.0 | 5.73e-01 | 100.0% | 50.0% |
| 6kkiA01 | 1.20.1720.10 | Mainly Alpha › Up-down Bundle › Multidrug resistance protein D › Multidrug resistance protein D | 0.82 | 71.0 | 4.95e-01 | 100.0% | 30.7% |
| 4qiqA00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.81 | 73.0 | 4.86e-01 | 100.0% | 26.4% |
| 4pypA00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.80 | 74.0 | 4.89e-01 | 100.0% | 26.6% |
| 4gc0A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.79 | 73.0 | 5.66e-01 | 100.0% | 55.0% |
| 4iu9B01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.78 | 71.0 | 5.67e-01 | 100.0% | 51.8% |
| 4iu9B02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.78 | 72.0 | 5.96e-01 | 100.0% | 62.6% |
| 8sbeA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.75 | 65.0 | 5.51e-01 | 100.0% | 57.1% |
| 2cfqA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.75 | 67.0 | 5.50e-01 | 100.0% | 54.7% |
| 7xpzA01 | 1.20.1720.10 | Mainly Alpha › Up-down Bundle › Multidrug resistance protein D › Multidrug resistance protein D | 0.71 | 64.0 | 4.44e-01 | 100.0% | 30.2% |
| 2cfqA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.69 | 62.0 | 5.21e-01 | 99.2% | 89.8% |
| 1wp1B01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.61 | 55.0 | 3.86e-01 | 98.3% | 68.4% |
| 4k7rA01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.61 | 54.0 | 3.88e-01 | 98.3% | 64.4% |
| 5azsC01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.61 | 54.0 | 3.85e-01 | 98.3% | 63.7% |
| 1b5lA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.58 | 51.0 | 4.68e-01 | 95.0% | 94.1% |
| 2efkA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.56 | 38.0 | 3.05e-01 | 70.6% | 80.5% |
| 1nzeA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.55 | 43.0 | 4.48e-01 | 91.6% | 88.4% |
| 3ejbH02 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.55 | 50.0 | 3.88e-01 | 100.0% | 84.4% |
| 3h36A00 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.54 | 35.0 | 4.21e-01 | 86.6% | 100.0% |
| 1cnt200 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.53 | 48.0 | 4.66e-01 | 99.2% | 90.8% |
| 2b5dX02 | 1.20.1430.10 | Mainly Alpha › Up-down Bundle › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase, middle domain | 0.53 | 41.0 | 4.17e-01 | 82.4% | 85.1% |
| 2khmA01 | 1.10.10.1350 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain | 0.52 | 36.0 | 3.78e-01 | 90.8% | 78.7% |
| 4rh7A01 | 1.20.920.20 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › | 0.52 | 43.0 | 2.99e-01 | 89.1% | 90.3% |
| 3ziuA01 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.52 | 43.0 | 3.51e-01 | 92.4% | 64.3% |
| 6tqfA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.51 | 45.0 | 3.21e-01 | 100.0% | 48.1% |
| 1ic8A01 | 1.10.260.40 | Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains | 0.51 | 29.0 | 3.25e-01 | 73.1% | 70.2% |
ECOD (99)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1566580 | 5050.1.1.71 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2, MFS_1 | 0.99 | 97.0 | 7.24e-01 | 100.0% | 48.2% |
| 2388968 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.98 | 94.0 | 7.05e-01 | 100.0% | 47.4% |
| 4243032 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.98 | 88.0 | 6.35e-01 | 93.3% | 39.6% |
| 2899908 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.97 | 90.0 | 6.91e-01 | 100.0% | 49.1% |
| 5051571 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.90 | 79.0 | 6.54e-01 | 100.0% | 56.4% |
| 5014402 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.89 | 81.0 | 6.79e-01 | 100.0% | 61.1% |
| 3511776 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.88 | 80.0 | 6.48e-01 | 100.0% | 55.6% |
| 4998387 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.86 | 76.0 | 6.30e-01 | 100.0% | 56.4% |
| 4473661 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.86 | 78.0 | 5.95e-01 | 100.0% | 45.6% |
| 3590328 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.86 | 75.0 | 6.42e-01 | 100.0% | 61.1% |
| 3987427 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.86 | 75.0 | 6.23e-01 | 100.0% | 56.4% |
| 3586957 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.86 | 77.0 | 6.32e-01 | 100.0% | 55.6% |
| 4934758 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.86 | 74.0 | 6.35e-01 | 100.0% | 60.6% |
| 3172047 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.85 | 76.0 | 6.10e-01 | 100.0% | 51.4% |
| 4992292 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.85 | 75.0 | 6.42e-01 | 100.0% | 61.7% |
| 4992315 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.85 | 74.0 | 6.37e-01 | 100.0% | 61.1% |
| 3269514 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.85 | 77.0 | 6.11e-01 | 100.0% | 51.1% |
| 3957618 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.85 | 77.0 | 5.50e-01 | 100.0% | 36.8% |
| 3695163 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.85 | 75.0 | 5.84e-01 | 100.0% | 46.1% |
| 5015087 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.85 | 78.0 | 6.06e-01 | 100.0% | 48.2% |
| 3284086 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.84 | 76.0 | 6.00e-01 | 100.0% | 49.8% |
| 3181920 | 5050.1.1.12 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › TRI12 | 0.84 | 76.0 | 5.56e-01 | 100.0% | 39.3% |
| 3188303 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.84 | 75.0 | 5.77e-01 | 100.0% | 45.2% |
| 3724333 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.84 | 77.0 | 6.20e-01 | 100.0% | 54.0% |
| 3388186 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.84 | 77.0 | 6.26e-01 | 100.0% | 56.4% |
| 5058288 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.84 | 72.0 | 6.20e-01 | 100.0% | 61.1% |
| 3476133 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.84 | 77.0 | 6.01e-01 | 100.0% | 49.4% |
| 4633155 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.84 | 76.0 | 6.12e-01 | 100.0% | 53.5% |
| 3691893 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.84 | 75.0 | 6.07e-01 | 100.0% | 53.0% |
| 4989825 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.84 | 75.0 | 6.27e-01 | 100.0% | 58.5% |
| 3693542 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.84 | 76.0 | 5.97e-01 | 100.0% | 50.0% |
| 4033228 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.84 | 75.0 | 5.45e-01 | 100.0% | 37.6% |
| 4137379 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.84 | 74.0 | 6.22e-01 | 100.0% | 58.9% |
| 5031979 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.83 | 75.0 | 6.32e-01 | 100.0% | 60.0% |
| 3729507 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.83 | 74.0 | 5.84e-01 | 100.0% | 49.1% |
| 3688890 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.83 | 78.0 | 6.22e-01 | 100.0% | 55.5% |
| 5069651 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.83 | 73.0 | 6.28e-01 | 100.0% | 62.2% |
| 3590809 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.83 | 74.0 | 5.87e-01 | 100.0% | 49.6% |
| 3275173 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.83 | 77.0 | 6.18e-01 | 100.0% | 54.9% |
| 3286865 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.82 | 73.0 | 6.12e-01 | 100.0% | 58.9% |
| 3592033 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.82 | 77.0 | 6.19e-01 | 100.0% | 57.2% |
| 4991729 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.82 | 77.0 | 6.14e-01 | 100.0% | 55.5% |
| 3279891 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.82 | 73.0 | 6.09e-01 | 100.0% | 57.9% |
| 3736289 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.82 | 76.0 | 5.93e-01 | 100.0% | 51.2% |
| 4018515 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.81 | 72.0 | 6.00e-01 | 100.0% | 56.5% |
| 4275945 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.81 | 74.0 | 5.84e-01 | 100.0% | 50.4% |
| 3969002 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.81 | 72.0 | 6.08e-01 | 100.0% | 59.5% |
| 3956688 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.81 | 76.0 | 6.12e-01 | 100.0% | 59.2% |
| 3781049 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.81 | 74.0 | 5.90e-01 | 100.0% | 52.0% |
| 3721346 | 5050.1.1.12 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › TRI12 | 0.81 | 60.0 | 6.00e-01 | 76.5% | 75.8% |
| 3347565 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.81 | 75.0 | 5.91e-01 | 100.0% | 52.8% |
| 3697137 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.81 | 75.0 | 5.79e-01 | 100.0% | 49.6% |
| 4961016 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.80 | 75.0 | 6.04e-01 | 100.0% | 55.4% |
| 5009990 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.80 | 72.0 | 6.05e-01 | 100.0% | 59.0% |
| 3638409 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.80 | 75.0 | 6.18e-01 | 100.0% | 59.5% |
| 3936681 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.80 | 75.0 | 5.88e-01 | 100.0% | 52.8% |
| 1700024 | 5050.1.1.8 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 | 0.80 | 74.0 | 6.27e-01 | 100.0% | 63.1% |
| 3287618 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.80 | 74.0 | 5.92e-01 | 100.0% | 82.2% |
| 3939674 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.80 | 74.0 | 5.82e-01 | 100.0% | 55.7% |
| 3574447 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.80 | 73.0 | 5.69e-01 | 100.0% | 48.8% |
| 4153328 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.80 | 70.0 | 5.85e-01 | 100.0% | 56.5% |
| 3336589 | 5050.1.1.8 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 | 0.79 | 73.0 | 5.85e-01 | 100.0% | 53.2% |
| 3238457 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.79 | 74.0 | 5.89e-01 | 100.0% | 55.4% |
| 3945908 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.79 | 72.0 | 5.92e-01 | 100.0% | 56.6% |
| 3942023 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.79 | 70.0 | 5.27e-01 | 100.0% | 40.7% |
| 4659016 | 5050.1.1.10 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_2 | 0.79 | 74.0 | 5.75e-01 | 100.0% | 49.8% |
| 4394631 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.79 | 70.0 | 5.26e-01 | 100.0% | 40.7% |
| 3727454 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.79 | 69.0 | 5.46e-01 | 100.0% | 48.3% |
| 3532431 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.79 | 74.0 | 5.99e-01 | 100.0% | 86.2% |
| 5053012 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.79 | 74.0 | 5.98e-01 | 100.0% | 87.6% |
| 3476998 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.79 | 70.0 | 5.64e-01 | 100.0% | 51.1% |
| 3972403 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.79 | 69.0 | 5.78e-01 | 100.0% | 56.5% |
| 3191418 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.79 | 73.0 | 5.64e-01 | 99.2% | 75.7% |
| 3164002 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.79 | 72.0 | 5.88e-01 | 100.0% | 87.9% |
| 3650966 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.78 | 72.0 | 5.74e-01 | 100.0% | 56.5% |
| 4352176 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.78 | 72.0 | 5.47e-01 | 100.0% | 47.8% |
| 3977977 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.78 | 69.0 | 5.72e-01 | 98.3% | 55.6% |
| 5009963 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.78 | 68.0 | 5.69e-01 | 100.0% | 56.3% |
| 5011444 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.78 | 69.0 | 5.72e-01 | 100.0% | 56.5% |
| 3573715 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.78 | 72.0 | 5.79e-01 | 100.0% | 59.1% |
| 3165295 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.78 | 71.0 | 5.81e-01 | 100.0% | 58.6% |
| 3925169 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.77 | 59.0 | 5.50e-01 | 88.2% | 64.0% |
| 3969784 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.77 | 71.0 | 5.85e-01 | 100.0% | 87.3% |
| 4584566 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.77 | 71.0 | 5.50e-01 | 100.0% | 75.1% |
| 4488931 | 5050.1.1.41 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_Mycoplasma | 0.76 | 70.0 | 5.63e-01 | 100.0% | 55.6% |
| 3174963 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.76 | 70.0 | 5.45e-01 | 100.0% | 74.0% |
| 3541710 | 5050.1.1.10 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_2 | 0.76 | 70.0 | 5.30e-01 | 100.0% | 45.1% |
| 3834014 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.76 | 71.0 | 5.74e-01 | 100.0% | 78.1% |
| 4281450 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.76 | 67.0 | 5.42e-01 | 100.0% | 51.1% |
| 3598668 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.76 | 69.0 | 5.64e-01 | 100.0% | 55.4% |
| 3938126 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.76 | 69.0 | 5.56e-01 | 100.0% | 53.2% |
| 3988302 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.75 | 68.0 | 5.91e-01 | 100.0% | 65.0% |
| 5009429 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.75 | 68.0 | 5.53e-01 | 100.0% | 53.4% |
| 3390980 | 5050.1.1.5 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Folate_carrier | 0.75 | 66.0 | 4.50e-01 | 100.0% | 27.1% |
| 3948187 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.75 | 69.0 | 5.27e-01 | 100.0% | 70.0% |
| 3890785 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.74 | 69.0 | 5.60e-01 | 100.0% | 77.7% |
| 5026270 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.74 | 68.0 | 5.69e-01 | 100.0% | 91.0% |
| 3967980 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.74 | 67.0 | 5.52e-01 | 100.0% | 87.4% |
| 3240227 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.73 | 68.0 | 5.43e-01 | 100.0% | 77.7% |
D2
medium
residues 147-222
Domain cluster:
representative
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF07690.22 best | MFS_1 | 42.4 | 6.10e-11 | 100.0% | 21.0% |
| PF00854.28 | PTR2 | 66.7 | 2.70e-18 | 85.5% | 13.8% |
D3
medium
residues 255-312_431-465_492-503
Domain cluster:
representative
CATH (43)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4m0mA03 | 1.20.1270.430 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.78 | 37.0 | 4.20e-01 | 72.4% | 59.5% |
| 3owaB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.76 | 49.0 | 4.25e-01 | 88.6% | 43.9% |
| 1yvwA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.75 | 38.0 | 4.02e-01 | 86.7% | 54.3% |
| 4d2dA00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.74 | 66.0 | 4.25e-01 | 97.1% | 91.1% |
| 4gc0A02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.71 | 57.0 | 4.49e-01 | 87.6% | 85.8% |
| 8ex5A02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.71 | 59.0 | 4.57e-01 | 88.6% | 96.8% |
| 1vcsA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.70 | 42.0 | 4.31e-01 | 86.7% | 61.8% |
| 1pw4A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.69 | 56.0 | 4.50e-01 | 88.6% | 94.7% |
| 2ot4A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.69 | 43.0 | 4.30e-01 | 85.7% | 60.7% |
| 4gc0A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.69 | 56.0 | 4.28e-01 | 88.6% | 59.8% |
| 1qdbA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.69 | 40.0 | 3.62e-01 | 87.6% | 42.0% |
| 4h33A00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.68 | 56.0 | 5.92e-01 | 86.7% | 100.0% |
| 1oahA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.68 | 40.0 | 3.64e-01 | 86.7% | 42.3% |
| 3l0iA01 | 1.20.120.1520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.68 | 46.0 | 3.86e-01 | 84.8% | 41.5% |
| 1j5wA02 | 1.20.58.180 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 | 0.68 | 37.0 | 4.24e-01 | 83.8% | 71.4% |
| 1w0bA01 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.68 | 41.0 | 4.41e-01 | 83.8% | 69.6% |
| 1z5zA02 | 1.20.120.850 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SWI2/SNF2 ATPases, N-terminal domain | 0.67 | 39.0 | 4.46e-01 | 89.5% | 77.6% |
| 3l1nA02 | 1.20.1280.140 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.67 | 41.0 | 4.41e-01 | 86.7% | 72.4% |
| 3w0lD02 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.67 | 55.0 | 3.82e-01 | 88.6% | 62.9% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.66 | 44.0 | 4.75e-01 | 87.6% | 83.5% |
| 7zh0A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.66 | 57.0 | 3.83e-01 | 95.2% | 89.7% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.65 | 51.0 | 4.95e-01 | 81.9% | 99.1% |
| 1t72A02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.64 | 41.0 | 4.27e-01 | 87.6% | 69.4% |
| 4dxwA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.62 | 49.0 | 4.82e-01 | 82.9% | 85.7% |
| 3o7pA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.62 | 50.0 | 4.04e-01 | 88.6% | 56.0% |
| 3kavA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.62 | 46.0 | 4.72e-01 | 78.1% | 100.0% |
| 2uxwA04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.62 | 40.0 | 3.71e-01 | 87.6% | 51.5% |
| 1qv9A02 | 6.10.140.120 | Special › Helix non-globular › Helix Hairpins › | 0.59 | 39.0 | 3.97e-01 | 87.6% | 68.0% |
| 3pwxA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.57 | 48.0 | 3.92e-01 | 88.6% | 86.4% |
| 1a7mA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.57 | 50.0 | 4.21e-01 | 98.1% | 77.8% |
| 2mgxA00 | 1.20.940.10 | Mainly Alpha › Up-down Bundle › RNA Binding Protein, Prp18; Chain A › Functional domain of the splicing factor Prp18 | 0.56 | 44.0 | 4.18e-01 | 85.7% | 72.5% |
| 1nu7D01 | 1.20.120.750 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Staphylcoagulase, helix bundle domain 1 | 0.56 | 37.0 | 3.43e-01 | 87.6% | 51.9% |
| 1bbnA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.55 | 46.0 | 4.27e-01 | 89.5% | 82.7% |
| 2aniA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.54 | 50.0 | 3.50e-01 | 100.0% | 53.6% |
| 6zhiB02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.54 | 35.0 | 3.92e-01 | 72.4% | 84.3% |
| 4ap2B01 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.53 | 43.0 | 3.97e-01 | 86.7% | 79.9% |
| 3cxbA03 | 1.10.1740.30 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Secreted effector protein SifA helical domain | 0.53 | 39.0 | 4.40e-01 | 100.0% | 100.0% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.52 | 42.0 | 4.30e-01 | 83.8% | 96.0% |
| 5azpB01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.52 | 44.0 | 3.05e-01 | 93.3% | 59.3% |
| 1yq3C02 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.52 | 38.0 | 3.81e-01 | 88.6% | 75.9% |
| 2l3lA01 | 1.20.58.1250 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain | 0.52 | 39.0 | 3.89e-01 | 97.1% | 77.4% |
| 2fsfB04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.50 | 46.0 | 3.65e-01 | 100.0% | 90.1% |
| 3ddeB00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.50 | 42.0 | 3.36e-01 | 95.2% | 67.1% |
ECOD (72)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3699502 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.78 | 45.0 | 4.27e-01 | 85.7% | 48.0% |
| 3241024 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.78 | 53.0 | 4.06e-01 | 70.5% | 91.7% |
| 3968650 | 633.6.1.0 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like | 0.77 | 46.0 | 4.66e-01 | 88.6% | 60.0% |
| 4542067 | 1101.1.1.5 ↗ | alpha bundles › Uncharacterized protein LPG2271 › Uncharacterized protein LPG2271 › Uncharacterized protein LPG2271 › PF27081 | 0.74 | 56.0 | 5.61e-01 | 78.1% | 81.0% |
| 3793322 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.73 | 61.0 | 4.67e-01 | 88.6% | 87.8% |
| 3600129 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.73 | 61.0 | 4.77e-01 | 88.6% | 59.0% |
| 3700663 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.73 | 45.0 | 4.64e-01 | 84.8% | 65.0% |
| 1868087 | 622.1.1.2 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › HsbA | 0.73 | 41.0 | 4.49e-01 | 83.8% | 67.4% |
| 3793666 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.73 | 60.0 | 4.75e-01 | 88.6% | 61.9% |
| 4995211 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.72 | 60.0 | 4.79e-01 | 88.6% | 60.5% |
| 3998516 | 5050.1.1.6 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › OATP | 0.72 | 59.0 | 4.64e-01 | 88.6% | 62.8% |
| 3413205 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.71 | 58.0 | 4.67e-01 | 88.6% | 64.9% |
| 3989360 | 6155.1.1.0 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter | 0.70 | 38.0 | 4.00e-01 | 88.6% | 57.9% |
| 3759091 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.70 | 58.0 | 4.53e-01 | 88.6% | 53.6% |
| 3976445 | 5050.1.1.10 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_2 | 0.70 | 57.0 | 4.44e-01 | 88.6% | 58.3% |
| 3500239 | 604.1.1.194 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › MENTAL | 0.70 | 45.0 | 4.61e-01 | 86.7% | 68.0% |
| 3371141 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.70 | 43.0 | 4.30e-01 | 84.8% | 59.1% |
| 4351650 | 5050.1.1.23 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › CLN3 | 0.69 | 56.0 | 4.42e-01 | 87.6% | 78.2% |
| 3442863 | 633.4.1.0 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor | 0.69 | 57.0 | 4.85e-01 | 88.6% | 76.5% |
| 3879763 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.69 | 52.0 | 3.80e-01 | 79.0% | 83.8% |
| 3932388 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.69 | 56.0 | 4.41e-01 | 88.6% | 90.9% |
| 3593035 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.68 | 56.0 | 4.26e-01 | 88.6% | 55.2% |
| 3972434 | 604.5.1.33 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › FUSC | 0.68 | 56.0 | 4.92e-01 | 88.6% | 70.8% |
| 3693483 | 5050.1.1.8 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 | 0.68 | 56.0 | 4.25e-01 | 88.6% | 58.0% |
| 3609115 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.68 | 56.0 | 4.48e-01 | 88.6% | 95.6% |
| 3312910 | 603.1.1.111 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › TBCC_N | 0.68 | 40.0 | 4.31e-01 | 84.8% | 67.8% |
| 3989863 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.68 | 54.0 | 4.49e-01 | 86.7% | 67.9% |
| 3187021 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.68 | 55.0 | 4.27e-01 | 88.6% | 56.2% |
| 3497911 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.67 | 52.0 | 4.79e-01 | 82.9% | 100.0% |
| 3743791 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.67 | 54.0 | 3.61e-01 | 88.6% | 28.7% |
| 3253260 | 5069.1.3.4 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › CybS | 0.66 | 41.0 | 4.11e-01 | 83.8% | 59.6% |
| 5014265 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.66 | 36.0 | 3.96e-01 | 81.9% | 64.7% |
| 3394275 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.65 | 53.0 | 4.18e-01 | 87.6% | 90.0% |
| 3796920 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.64 | 52.0 | 4.17e-01 | 88.6% | 87.9% |
| 3338353 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.64 | 52.0 | 4.53e-01 | 88.6% | 81.2% |
| 3600308 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.64 | 50.0 | 3.87e-01 | 84.8% | 55.4% |
| 3928795 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.64 | 37.0 | 3.93e-01 | 84.8% | 63.2% |
| 3980942 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.63 | 39.0 | 3.98e-01 | 87.6% | 63.0% |
| 5042408 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.63 | 43.0 | 4.26e-01 | 86.7% | 66.4% |
| 4937262 | 1188.1.1.1 ↗ | alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter › Zip | 0.63 | 51.0 | 3.82e-01 | 85.7% | 78.8% |
| 3250875 | 5059.1.1.16 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › SLC35F | 0.62 | 55.0 | 3.69e-01 | 93.3% | 59.7% |
| 4995305 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.62 | 40.0 | 4.21e-01 | 86.7% | 71.6% |
| 3609099 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.62 | 38.0 | 4.10e-01 | 87.6% | 71.1% |
| 1563531 | 633.6.1.6 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACAD9-ACADV_C | 0.62 | 40.0 | 3.63e-01 | 87.6% | 48.2% |
| 3727838 | 5050.1.1.10 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_2 | 0.62 | 46.0 | 3.50e-01 | 78.1% | 91.9% |
| 3232632 | 633.10.1.15 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › Transmemb_17 | 0.62 | 50.0 | 4.67e-01 | 87.6% | 97.7% |
| 3206970 | 3327.1.1.1 ↗ | alpha bundles › HET-S N-terminal domain › HET-S N-terminal domain › HET-S N-terminal domain › HeLo | 0.61 | 55.0 | 4.40e-01 | 99.0% | 90.5% |
| 3411860 | 633.6.1.6 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACAD9-ACADV_C | 0.61 | 39.0 | 3.51e-01 | 87.6% | 45.3% |
| 4972372 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.60 | 48.0 | 3.93e-01 | 88.6% | 63.8% |
| 3266809 | 5054.1.1.2 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans | 0.60 | 50.0 | 3.16e-01 | 91.4% | 53.1% |
| 3452617 | 5059.1.1.24 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › PUNUT | 0.60 | 52.0 | 3.70e-01 | 97.1% | 70.7% |
| 4474376 | 7014.1.1.1 ↗ | alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA | 0.60 | 43.0 | 4.02e-01 | 75.2% | 68.9% |
| 4973584 | 604.3.1.51 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › 8xMP | 0.59 | 47.0 | 5.10e-01 | 93.3% | 100.0% |
| 3241203 | 544.1.1.0 ↗ | alpha bundles › Functional domain of the splicing factor Prp18 › Functional domain of the splicing factor Prp18 › Functional domain of the splicing factor Prp18 | 0.58 | 46.0 | 4.43e-01 | 85.7% | 77.5% |
| 3802402 | 633.22.1.0 ↗ | alpha bundles › Bromodomain-like › Vitamin K epoxide reductase (VKOR) › Vitamin K epoxide reductase (VKOR) | 0.58 | 46.0 | 4.08e-01 | 85.7% | 75.5% |
| 3607681 | 633.10.1.15 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › Transmemb_17 | 0.58 | 42.0 | 3.96e-01 | 77.1% | 100.0% |
| 3726235 | 5069.1.1.7 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 | 0.58 | 46.0 | 3.71e-01 | 87.6% | 98.2% |
| 3433766 | 5050.1.1.28 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › BT1 | 0.58 | 46.0 | 3.62e-01 | 85.7% | 58.2% |
| 3216171 | 5001.1.1.25 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Sru | 0.58 | 48.0 | 3.35e-01 | 88.6% | 60.6% |
| 4026608 | 5050.1.1.28 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › BT1 | 0.58 | 45.0 | 3.75e-01 | 87.6% | 99.0% |
| 3240702 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.57 | 48.0 | 3.73e-01 | 100.0% | 42.4% |
| 5056276 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.56 | 49.0 | 4.26e-01 | 95.2% | 100.0% |
| 3718272 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.55 | 34.0 | 3.48e-01 | 85.7% | 61.9% |
| 5049261 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.55 | 41.0 | 3.53e-01 | 81.9% | 49.7% |
| 4023477 | 601.1.2.72 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › SesA | 0.55 | 42.0 | 3.69e-01 | 81.9% | 84.4% |
| 4989411 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.54 | 47.0 | 3.73e-01 | 100.0% | 46.5% |
| 3387995 | 3758.2.1.1 ↗ | alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB | 0.54 | 42.0 | 3.45e-01 | 83.8% | 94.0% |
| 3393875 | 101.1.1.427 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › NT_N | 0.53 | 38.0 | 4.00e-01 | 77.1% | 83.2% |
| 3593724 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.53 | 45.0 | 4.27e-01 | 92.4% | 85.6% |
| 4237660 | 1008.1.1.0 ↗ | alpha bundles › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain | 0.53 | 42.0 | 4.06e-01 | 97.1% | 75.0% |
| 3626530 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.53 | 42.0 | 4.39e-01 | 92.4% | 93.7% |
| 3689003 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.52 | 45.0 | 3.50e-01 | 95.2% | 44.8% |
D4
medium
residues 313-430_466-491
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00854.28 best | PTR2 | 68.4 | 7.80e-19 | 97.2% | 33.4% |
CATH (44)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4d2dA00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.91 | 88.0 | 5.88e-01 | 100.0% | 35.4% |
| 4oh3A00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.90 | 86.0 | 5.67e-01 | 100.0% | 38.3% |
| 4w6vA00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.90 | 88.0 | 5.78e-01 | 100.0% | 35.4% |
| 4uvmA00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.88 | 85.0 | 5.55e-01 | 100.0% | 36.6% |
| 6gs4A00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.86 | 82.0 | 5.53e-01 | 100.0% | 38.9% |
| 4q65A00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.80 | 77.0 | 5.24e-01 | 100.0% | 36.6% |
| 4gc0A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.75 | 69.0 | 5.71e-01 | 100.0% | 77.5% |
| 4pypA00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.74 | 69.0 | 4.77e-01 | 100.0% | 36.2% |
| 7dl9B02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.74 | 69.0 | 6.10e-01 | 100.0% | 86.2% |
| 8sbeA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.73 | 68.0 | 6.17e-01 | 100.0% | 89.8% |
| 2cfqA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.73 | 68.0 | 5.93e-01 | 100.0% | 75.9% |
| 8ex5A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.71 | 67.0 | 6.02e-01 | 100.0% | 83.2% |
| 8ex5A02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.71 | 65.0 | 5.62e-01 | 100.0% | 82.0% |
| 6kkiA01 | 1.20.1720.10 | Mainly Alpha › Up-down Bundle › Multidrug resistance protein D › Multidrug resistance protein D | 0.71 | 66.0 | 4.82e-01 | 100.0% | 42.4% |
| 7d5qA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.71 | 66.0 | 6.06e-01 | 100.0% | 90.7% |
| 4tpjA00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.70 | 66.0 | 4.55e-01 | 100.0% | 37.3% |
| 1rj1A00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.70 | 40.0 | 4.03e-01 | 78.5% | 56.1% |
| 8sbeA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.69 | 64.0 | 5.76e-01 | 100.0% | 80.6% |
| 4gc0A02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.68 | 63.0 | 5.40e-01 | 100.0% | 73.5% |
| 7dl9A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.68 | 63.0 | 5.70e-01 | 100.0% | 82.0% |
| 1pw4A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.66 | 61.0 | 5.36e-01 | 100.0% | 77.5% |
| 3o7qA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.66 | 61.0 | 5.50e-01 | 100.0% | 81.2% |
| 6rv2A00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.64 | 45.0 | 3.74e-01 | 72.2% | 68.5% |
| 3hhcC00 | 1.20.1250.60 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interferon lambda | 0.63 | 39.0 | 3.90e-01 | 99.3% | 58.9% |
| 1oq4A00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.61 | 46.0 | 3.47e-01 | 77.8% | 80.6% |
| 1j5wA02 | 1.20.58.180 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 | 0.60 | 32.0 | 4.27e-01 | 96.5% | 96.1% |
| 3ug9A02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.59 | 42.0 | 3.55e-01 | 72.9% | 98.7% |
| 1wp1B01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.59 | 46.0 | 3.37e-01 | 81.9% | 65.7% |
| 1n1fA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.57 | 36.0 | 3.57e-01 | 100.0% | 57.5% |
| 3dyjA01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.56 | 47.0 | 4.55e-01 | 90.3% | 100.0% |
| 4mt4A00 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.56 | 44.0 | 3.07e-01 | 81.9% | 57.0% |
| 2okuA00 | 1.20.120.470 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Acyl-CoA dehydrogenase, C-terminal domain | 0.56 | 34.0 | 3.75e-01 | 75.7% | 73.0% |
| 2incA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.55 | 46.0 | 3.18e-01 | 89.6% | 95.3% |
| 1h0oA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.54 | 43.0 | 3.45e-01 | 91.0% | 42.7% |
| 3ay5A01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.54 | 44.0 | 4.61e-01 | 86.8% | 98.5% |
| 1td6A01 | 1.20.1480.10 | Mainly Alpha › Up-down Bundle › hypothetical protein mp506/mpn330, domain 1 › hypothetical protein mp506/mpn330, domain 1 | 0.53 | 35.0 | 4.12e-01 | 81.9% | 94.1% |
| 4jioA01 | 1.20.120.560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain | 0.53 | 40.0 | 3.85e-01 | 77.8% | 88.2% |
| 3l6aA01 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.53 | 32.0 | 2.92e-01 | 72.2% | 44.2% |
| 7qoaA01 | 1.10.4160.10 | Mainly Alpha › Orthogonal Bundle › Hydantoin permease › Hydantoin permease | 0.52 | 46.0 | 3.39e-01 | 96.5% | 75.1% |
| 2b2hA00 | 1.10.3430.10 | Mainly Alpha › Orthogonal Bundle › Ammonium transporter fold › Ammonium transporter AmtB like domains | 0.51 | 46.0 | 3.42e-01 | 100.0% | 79.3% |
| 2f2bA00 | 1.20.1080.10 | Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. | 0.51 | 42.0 | 3.53e-01 | 88.2% | 64.5% |
| 3kp9A01 | 1.20.1440.130 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › VKOR domain | 0.51 | 36.0 | 3.55e-01 | 74.3% | 92.0% |
| 1b5lA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.50 | 39.0 | 3.88e-01 | 81.2% | 88.8% |
| 1xwjA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.50 | 39.0 | 4.08e-01 | 79.9% | 88.5% |
ECOD (99)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3946372 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.99 | 97.0 | 6.31e-01 | 100.0% | 35.8% |
| 3948865 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.92 | 89.0 | 7.07e-01 | 100.0% | 73.1% |
| 4551070 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.92 | 89.0 | 7.01e-01 | 100.0% | 71.5% |
| 3964798 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.91 | 89.0 | 7.26e-01 | 100.0% | 73.2% |
| 3674375 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.90 | 86.0 | 5.52e-01 | 100.0% | 35.1% |
| 3457656 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.90 | 86.0 | 5.49e-01 | 100.0% | 36.2% |
| 3750490 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.89 | 86.0 | 5.68e-01 | 100.0% | 35.2% |
| 3413390 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.89 | 86.0 | 6.69e-01 | 100.0% | 65.8% |
| 2137980 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.89 | 85.0 | 6.70e-01 | 100.0% | 69.5% |
| 3509472 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.88 | 85.0 | 5.66e-01 | 100.0% | 36.8% |
| 3385026 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.88 | 84.0 | 5.82e-01 | 99.3% | 50.5% |
| 3241816 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.87 | 84.0 | 6.65e-01 | 100.0% | 65.8% |
| 3430628 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.86 | 82.0 | 6.20e-01 | 100.0% | 64.9% |
| 2162322 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.85 | 82.0 | 6.53e-01 | 100.0% | 61.7% |
| 3588630 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.77 | 73.0 | 6.38e-01 | 100.0% | 81.0% |
| 3391667 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.77 | 72.0 | 6.09e-01 | 100.0% | 76.4% |
| 3413601 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.76 | 71.0 | 5.97e-01 | 100.0% | 73.2% |
| 3480939 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.76 | 71.0 | 6.10e-01 | 100.0% | 77.7% |
| 3483196 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.76 | 71.0 | 6.10e-01 | 100.0% | 77.7% |
| 3518309 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.76 | 71.0 | 6.19e-01 | 100.0% | 81.4% |
| 3982121 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.75 | 52.0 | 4.90e-01 | 81.9% | 58.3% |
| 3232185 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.75 | 70.0 | 6.05e-01 | 100.0% | 79.5% |
| 3283512 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.75 | 70.0 | 6.05e-01 | 100.0% | 80.5% |
| 4207846 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.75 | 70.0 | 6.04e-01 | 100.0% | 79.1% |
| 4014823 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.75 | 69.0 | 6.02e-01 | 100.0% | 83.7% |
| 3991181 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.75 | 69.0 | 5.84e-01 | 100.0% | 72.8% |
| 3417107 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.75 | 70.0 | 6.03e-01 | 100.0% | 80.0% |
| 3729771 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.75 | 71.0 | 5.47e-01 | 100.0% | 58.6% |
| 3736631 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.75 | 69.0 | 5.78e-01 | 100.0% | 73.3% |
| 4971427 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.74 | 69.0 | 6.34e-01 | 100.0% | 89.1% |
| 3782009 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.74 | 69.0 | 5.97e-01 | 100.0% | 81.4% |
| 3238595 | 5050.1.1.4 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nucleoside_tran | 0.74 | 68.0 | 5.81e-01 | 100.0% | 77.8% |
| 3694605 | 5050.1.1.55 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr, MFS_1 | 0.74 | 69.0 | 4.98e-01 | 100.0% | 46.1% |
| 3174370 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.74 | 68.0 | 5.83e-01 | 100.0% | 79.1% |
| 3634997 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.74 | 69.0 | 5.53e-01 | 100.0% | 75.8% |
| 4944663 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.74 | 69.0 | 6.24e-01 | 98.6% | 89.2% |
| 3191002 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.73 | 68.0 | 5.67e-01 | 100.0% | 77.9% |
| 3278042 | 5050.1.1.60 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_3 | 0.73 | 69.0 | 6.09e-01 | 100.0% | 80.5% |
| 3874538 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.73 | 67.0 | 5.80e-01 | 100.0% | 76.2% |
| 4960606 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.73 | 69.0 | 6.02e-01 | 100.0% | 78.0% |
| 3185062 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.73 | 67.0 | 5.72e-01 | 100.0% | 82.5% |
| 3189902 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.73 | 67.0 | 5.81e-01 | 100.0% | 85.0% |
| 3684737 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.73 | 67.0 | 5.66e-01 | 100.0% | 77.9% |
| 3722487 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.73 | 67.0 | 5.70e-01 | 100.0% | 81.7% |
| 3194749 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.73 | 67.0 | 5.65e-01 | 100.0% | 74.9% |
| 3910336 | 5050.1.1.4 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nucleoside_tran | 0.73 | 67.0 | 5.52e-01 | 100.0% | 73.7% |
| 5026269 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.73 | 68.0 | 5.72e-01 | 100.0% | 78.3% |
| 3506187 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.73 | 67.0 | 5.92e-01 | 100.0% | 83.4% |
| 3726328 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.72 | 67.0 | 5.82e-01 | 100.0% | 79.5% |
| 3516576 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.72 | 67.0 | 5.84e-01 | 100.0% | 76.5% |
| 3227782 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.72 | 67.0 | 5.87e-01 | 100.0% | 75.2% |
| 5059306 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.72 | 67.0 | 5.92e-01 | 100.0% | 87.2% |
| 3723018 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.72 | 66.0 | 5.46e-01 | 100.0% | 71.4% |
| 4558305 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.72 | 66.0 | 5.61e-01 | 100.0% | 80.4% |
| 3248007 | 5050.1.1.4 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nucleoside_tran | 0.72 | 66.0 | 5.63e-01 | 100.0% | 76.1% |
| 3726453 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.72 | 65.0 | 5.56e-01 | 100.0% | 78.3% |
| 4156258 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.72 | 67.0 | 5.92e-01 | 100.0% | 84.5% |
| 5058287 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.72 | 67.0 | 6.08e-01 | 100.0% | 83.2% |
| 3741168 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.71 | 65.0 | 5.58e-01 | 100.0% | 80.4% |
| 4019453 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.71 | 66.0 | 5.43e-01 | 100.0% | 72.4% |
| 3312575 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.71 | 65.0 | 5.75e-01 | 100.0% | 78.6% |
| 3190748 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.71 | 65.0 | 5.49e-01 | 100.0% | 76.7% |
| 3220384 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.71 | 67.0 | 5.75e-01 | 100.0% | 72.1% |
| 3782291 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.71 | 65.0 | 5.46e-01 | 100.0% | 75.7% |
| 4555192 | 1079.1.1.5 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › DsbD_2 | 0.71 | 65.0 | 5.76e-01 | 97.9% | 89.5% |
| 4885751 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.71 | 65.0 | 5.68e-01 | 100.0% | 86.0% |
| 4573228 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.71 | 67.0 | 5.85e-01 | 100.0% | 76.6% |
| 4002385 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.71 | 60.0 | 5.59e-01 | 89.6% | 86.9% |
| 4146989 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.71 | 65.0 | 5.33e-01 | 100.0% | 68.8% |
| 3268174 | 5050.1.1.4 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nucleoside_tran | 0.71 | 65.0 | 5.59e-01 | 100.0% | 75.1% |
| 4960856 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.71 | 66.0 | 5.99e-01 | 100.0% | 83.7% |
| 3701105 | 5050.1.1.15 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nodulin-like | 0.71 | 65.0 | 5.03e-01 | 100.0% | 54.3% |
| 4207231 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.71 | 64.0 | 5.46e-01 | 100.0% | 81.6% |
| 3692241 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.70 | 64.0 | 5.53e-01 | 100.0% | 82.2% |
| 3693214 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.70 | 65.0 | 5.46e-01 | 100.0% | 76.6% |
| 4944038 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.70 | 66.0 | 5.93e-01 | 100.0% | 83.7% |
| 3182763 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.70 | 64.0 | 4.32e-01 | 100.0% | 34.4% |
| 3834000 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.70 | 65.0 | 5.79e-01 | 100.0% | 82.5% |
| 3429331 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.70 | 65.0 | 5.68e-01 | 100.0% | 75.2% |
| 3484948 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.70 | 64.0 | 5.56e-01 | 100.0% | 72.7% |
| 3176545 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.70 | 65.0 | 5.82e-01 | 100.0% | 80.5% |
| 4352176 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.70 | 65.0 | 5.19e-01 | 100.0% | 68.5% |
| 3662602 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.69 | 64.0 | 5.45e-01 | 100.0% | 71.3% |
| 3743461 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.69 | 63.0 | 5.41e-01 | 100.0% | 80.0% |
| 3282854 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.69 | 63.0 | 5.55e-01 | 100.0% | 76.2% |
| 3616712 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.69 | 63.0 | 5.36e-01 | 100.0% | 76.1% |
| 3616807 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.68 | 63.0 | 5.39e-01 | 100.0% | 71.1% |
| 3282784 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.68 | 63.0 | 5.60e-01 | 100.0% | 81.5% |
| 3922666 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.68 | 63.0 | 5.50e-01 | 100.0% | 75.7% |
| 3398782 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.68 | 63.0 | 5.53e-01 | 100.0% | 78.0% |
| 3782959 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.67 | 62.0 | 5.44e-01 | 100.0% | 86.2% |
| 3670870 | 5050.1.1.8 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 | 0.66 | 58.0 | 5.45e-01 | 93.1% | 78.2% |
| 4992292 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.66 | 59.0 | 5.53e-01 | 98.6% | 89.4% |
| 3733862 | 5050.1.1.12 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › TRI12 | 0.65 | 59.0 | 5.05e-01 | 100.0% | 70.0% |
| 3790985 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.64 | 58.0 | 5.05e-01 | 98.6% | 72.7% |
| 3264612 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.62 | 56.0 | 5.24e-01 | 100.0% | 85.6% |
| 3186879 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.56 | 40.0 | 3.68e-01 | 72.2% | 81.7% |
| 3638405 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.55 | 39.0 | 3.77e-01 | 100.0% | 64.2% |
| 3165999 | 3291.1.1.213 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › MscS_porin | 0.52 | 39.0 | 3.50e-01 | 78.5% | 88.1% |