←Back to structures
CAKLQH020000043.1__CAH1095666.1__SAMEA5780036_03721__00005
Bact-VirCAKLQH020000043.1__CAH1095666.1__SAMEA5780036_03721__00005
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-64
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02694.22 best | UPF0060 | 48.9 | 9.30e-13 | 84.4% | 44.9% |
CATH (62)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1zpyA00 | 6.10.140.1960 | Special › Helix non-globular › Helix Hairpins › | 0.91 | 78.0 | 6.79e-01 | 90.6% | 69.2% |
| 7zxkC01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.86 | 60.0 | 4.46e-01 | 73.4% | 100.0% |
| 2dq0A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.85 | 78.0 | 6.45e-01 | 100.0% | 65.4% |
| 3qo8A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.85 | 77.0 | 6.45e-01 | 100.0% | 64.2% |
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.85 | 66.0 | 6.30e-01 | 82.8% | 75.7% |
| 1w99A01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.84 | 74.0 | 5.28e-01 | 96.9% | 35.3% |
| 1x4tA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.83 | 63.0 | 6.64e-01 | 81.2% | 100.0% |
| 1cxzB00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.83 | 73.0 | 6.58e-01 | 96.9% | 79.1% |
| 1wdzA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.83 | 75.0 | 5.02e-01 | 100.0% | 29.0% |
| 3mq1A01 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.82 | 70.0 | 6.14e-01 | 92.2% | 70.7% |
| 1xwmA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.82 | 70.0 | 4.75e-01 | 92.2% | 28.8% |
| 1h7cA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.82 | 74.0 | 6.24e-01 | 98.4% | 70.9% |
| 2qf9A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.82 | 69.0 | 5.06e-01 | 90.6% | 39.7% |
| 1qu7A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.82 | 73.0 | 4.95e-01 | 100.0% | 32.6% |
| 1tjlA00 | 1.20.120.910 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain | 0.81 | 74.0 | 5.57e-01 | 100.0% | 45.5% |
| 8d7hD01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.81 | 61.0 | 4.42e-01 | 81.2% | 100.0% |
| 1hs7A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.80 | 66.0 | 5.77e-01 | 90.6% | 66.0% |
| 4id0A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.80 | 70.0 | 5.75e-01 | 95.3% | 54.5% |
| 1otkA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.80 | 67.0 | 4.40e-01 | 90.6% | 25.4% |
| 1lrzA03 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.79 | 63.0 | 6.45e-01 | 85.9% | 90.3% |
| 2qr4A01 | 1.20.140.70 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Oligopeptidase f, N-terminal domain | 0.79 | 71.0 | 5.24e-01 | 98.4% | 40.4% |
| 1ydxA02 | 1.10.287.1120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein | 0.79 | 71.0 | 6.33e-01 | 100.0% | 77.8% |
| 1io1A01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.78 | 70.0 | 5.11e-01 | 100.0% | 59.2% |
| 3g67A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.78 | 69.0 | 4.77e-01 | 100.0% | 31.9% |
| 2dnxA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.78 | 69.0 | 5.42e-01 | 98.4% | 50.0% |
| 3fxdB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.77 | 63.0 | 6.55e-01 | 89.1% | 96.6% |
| 3fppA03 | 6.10.140.1990 | Special › Helix non-globular › Helix Hairpins › | 0.77 | 67.0 | 6.10e-01 | 100.0% | 88.6% |
| 4mrsA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.76 | 66.0 | 4.17e-01 | 100.0% | 38.3% |
| 2pmsC00 | 6.10.140.920 | Special › Helix non-globular › Helix Hairpins › | 0.76 | 66.0 | 5.61e-01 | 100.0% | 68.8% |
| 4e6nA02 | 6.10.140.1010 | Special › Helix non-globular › Helix Hairpins › | 0.76 | 66.0 | 6.62e-01 | 96.9% | 97.0% |
| 1rq0A01 | 6.10.140.160 | Special › Helix non-globular › Helix Hairpins › | 0.76 | 66.0 | 6.11e-01 | 100.0% | 79.5% |
| 2rp4A00 | 6.10.280.60 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain | 0.76 | 55.0 | 5.32e-01 | 79.7% | 69.0% |
| 4l8jA04 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.74 | 60.0 | 6.16e-01 | 90.6% | 100.0% |
| 4biuE01 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.74 | 64.0 | 5.63e-01 | 100.0% | 67.3% |
| 1vf7A03 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.74 | 59.0 | 6.12e-01 | 90.6% | 100.0% |
| 2ycdA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.72 | 62.0 | 5.11e-01 | 96.9% | 56.4% |
| 4h63K00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.72 | 61.0 | 5.37e-01 | 96.9% | 63.3% |
| 2rdcA00 | 1.10.287.800 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 | 0.72 | 64.0 | 4.97e-01 | 96.9% | 66.9% |
| 5jrcA00 | 1.20.58.2140 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 61.0 | 4.50e-01 | 100.0% | 35.5% |
| 3icxA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.72 | 64.0 | 6.07e-01 | 100.0% | 86.7% |
| 3a6pA00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.72 | 60.0 | 3.26e-01 | 92.2% | 6.1% |
| 3vkgA12 | 1.10.287.2610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.71 | 61.0 | 4.27e-01 | 100.0% | 31.2% |
| 1b04A03 | 1.10.287.610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.70 | 52.0 | 5.31e-01 | 81.2% | 83.9% |
| 1wpaA01 | 6.10.140.340 | Special › Helix non-globular › Helix Hairpins › | 0.70 | 60.0 | 5.30e-01 | 100.0% | 72.7% |
| 1lq7A00 | 1.20.1270.70 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle | 0.70 | 47.0 | 4.72e-01 | 79.7% | 68.7% |
| 2lqgA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.69 | 58.0 | 4.60e-01 | 100.0% | 44.9% |
| 3apzA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.69 | 56.0 | 3.59e-01 | 95.3% | 19.4% |
| 1j1jA02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.68 | 52.0 | 4.77e-01 | 87.5% | 62.4% |
| 1wkbA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.68 | 50.0 | 4.10e-01 | 79.7% | 44.6% |
| 1vw4T01 | 6.10.330.20 | Special › Helix non-globular › Monooxygenase › | 0.68 | 52.0 | 4.46e-01 | 87.5% | 50.9% |
| 4iluA02 | 1.20.58.1290 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain | 0.68 | 49.0 | 4.07e-01 | 76.6% | 73.0% |
| 1zbtA01 | 6.10.140.1950 | Special › Helix non-globular › Helix Hairpins › | 0.68 | 55.0 | 5.09e-01 | 93.8% | 71.1% |
| 2yqyA00 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.68 | 55.0 | 4.43e-01 | 90.6% | 78.6% |
| 2db7A01 | 6.10.250.980 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.67 | 51.0 | 5.54e-01 | 98.4% | 98.1% |
| 3d36B02 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.67 | 52.0 | 5.31e-01 | 92.2% | 91.8% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.67 | 56.0 | 5.60e-01 | 95.3% | 97.0% |
| 2pvqA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.67 | 54.0 | 4.71e-01 | 93.8% | 61.3% |
| 2lw1A00 | 1.10.287.380 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain | 0.65 | 54.0 | 4.98e-01 | 96.9% | 77.6% |
| 4aifA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.62 | 44.0 | 3.46e-01 | 76.6% | 35.4% |
| 4agsA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.59 | 47.0 | 3.79e-01 | 90.6% | 45.2% |
| 2mpkA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.57 | 43.0 | 4.18e-01 | 84.4% | 77.0% |
| 3dcfA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 48.0 | 3.74e-01 | 95.3% | 45.8% |
ECOD (58)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5001217 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.88 | 81.0 | 7.60e-01 | 98.4% | 94.7% |
| 5069014 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.88 | 81.0 | 6.08e-01 | 98.4% | 61.4% |
| 3485540 | 603.1.1.1 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin | 0.87 | 80.0 | 5.69e-01 | 100.0% | 38.9% |
| 3386800 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.86 | 68.0 | 7.00e-01 | 82.8% | 93.3% |
| 3401214 | 3755.3.1.345 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Hobbit | 0.86 | 79.0 | 5.93e-01 | 100.0% | 46.2% |
| 4387171 | 603.5.1.18 ↗ | alpha bundles › STAT-like › FlgN-like › FlgN-like › Med30 | 0.86 | 80.0 | 5.84e-01 | 100.0% | 55.5% |
| 3229095 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.86 | 78.0 | 6.66e-01 | 100.0% | 67.0% |
| 4295915 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.85 | 78.0 | 6.04e-01 | 100.0% | 51.5% |
| 4955837 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.85 | 73.0 | 6.39e-01 | 95.3% | 65.3% |
| 4962781 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.85 | 77.0 | 7.27e-01 | 100.0% | 84.0% |
| 3443484 | 616.1.1.0 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain | 0.84 | 63.0 | 6.04e-01 | 82.8% | 68.9% |
| 3462297 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.84 | 77.0 | 7.27e-01 | 100.0% | 88.0% |
| 5078048 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.84 | 73.0 | 6.98e-01 | 96.9% | 82.7% |
| 3627873 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.84 | 73.0 | 6.89e-01 | 100.0% | 80.0% |
| 3560229 | 3291.1.1.230 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › TBCA_PH | 0.84 | 76.0 | 5.80e-01 | 100.0% | 50.0% |
| 3598313 | 4207.1.2.0 ↗ | alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region | 0.84 | 76.0 | 5.81e-01 | 98.4% | 49.6% |
| 3607008 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.83 | 77.0 | 6.64e-01 | 100.0% | 69.5% |
| 5056869 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.83 | 76.0 | 5.41e-01 | 100.0% | 38.3% |
| 3273435 | 604.12.1.5 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › SUV3_C | 0.83 | 67.0 | 6.20e-01 | 93.8% | 68.8% |
| 3588172 | 10.12.1.0 ↗ | beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix | 0.83 | 67.0 | 4.97e-01 | 85.9% | 38.0% |
| 3713201 | 4323.1.1.1 ↗ | alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › V_ATPase_I | 0.83 | 77.0 | 5.74e-01 | 100.0% | 44.1% |
| 4990488 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.83 | 74.0 | 6.36e-01 | 100.0% | 66.0% |
| 4994040 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.82 | 75.0 | 6.37e-01 | 100.0% | 66.0% |
| 4959934 | 616.1.1.0 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain | 0.81 | 58.0 | 5.50e-01 | 78.1% | 64.0% |
| 3665862 | 3826.1.1.0 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) | 0.81 | 72.0 | 5.83e-01 | 100.0% | 55.0% |
| 3702706 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.81 | 73.0 | 6.78e-01 | 100.0% | 83.7% |
| 3699463 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.80 | 73.0 | 4.96e-01 | 100.0% | 31.2% |
| 4674 | 192.7.1.1 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › FemAB | 0.80 | 64.0 | 6.38e-01 | 85.9% | 89.2% |
| 4612374 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.80 | 72.0 | 6.37e-01 | 100.0% | 70.0% |
| 4176312 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.79 | 72.0 | 6.16e-01 | 100.0% | 66.0% |
| 2555592 | 5069.1.1.3 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cyt_bd_oxida_I | 0.79 | 66.0 | 6.01e-01 | 92.2% | 72.9% |
| 5076982 | 611.2.1.0 ↗ | alpha bundles › N-cbl like › N-terminal domain of cbl (N-cbl) › N-terminal domain of cbl (N-cbl) | 0.79 | 66.0 | 5.57e-01 | 92.2% | 61.9% |
| 3377936 | 3922.1.1.173 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DUF3493 | 0.79 | 71.0 | 6.47e-01 | 100.0% | 84.7% |
| 3979204 | 605.2.1.8 ↗ | alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 › Caudo_TAP | 0.79 | 70.0 | 6.64e-01 | 98.4% | 84.0% |
| 3840138 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.79 | 72.0 | 6.10e-01 | 100.0% | 68.0% |
| 5041514 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.78 | 69.0 | 5.48e-01 | 98.4% | 50.8% |
| 4420321 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.78 | 63.0 | 5.03e-01 | 87.5% | 47.2% |
| 3975852 | 192.8.1.466 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › Caudo_TAP | 0.78 | 65.0 | 6.53e-01 | 92.2% | 90.8% |
| 162404 | 603.1.1.6 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin_2 | 0.78 | 69.0 | 5.42e-01 | 98.4% | 50.0% |
| 3592587 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.77 | 67.0 | 5.36e-01 | 96.9% | 77.6% |
| 1760269 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.77 | 67.0 | 5.50e-01 | 96.9% | 54.3% |
| 4009505 | 7079.1.1.1 ↗ | a+b complex topology › Phage tail fiber assembly protein › Phage tail fiber assembly protein › Phage tail fiber assembly protein › Caudo_TAP | 0.77 | 66.0 | 6.40e-01 | 93.8% | 85.7% |
| 4007897 | 3809.1.1.2 ↗ | alpha bundles › Uncharacterized protein CV0426 › Uncharacterized protein CV0426 › Uncharacterized protein CV0426 › Caudo_TAP | 0.77 | 66.0 | 6.40e-01 | 93.8% | 85.7% |
| 5040665 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.77 | 69.0 | 3.96e-01 | 100.0% | 11.8% |
| 4010637 | 3809.1.1.2 ↗ | alpha bundles › Uncharacterized protein CV0426 › Uncharacterized protein CV0426 › Uncharacterized protein CV0426 › Caudo_TAP | 0.77 | 63.0 | 6.18e-01 | 90.6% | 82.9% |
| 3545387 | 3602.1.1.0 ↗ | alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain | 0.77 | 68.0 | 5.60e-01 | 96.9% | 68.2% |
| 3609435 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.77 | 66.0 | 5.95e-01 | 98.4% | 87.8% |
| 3613914 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.76 | 68.0 | 6.46e-01 | 98.4% | 88.0% |
| 3526587 | 109.4.1.839 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Maestro_HEAT | 0.75 | 65.0 | 4.09e-01 | 100.0% | 19.7% |
| 5006188 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.75 | 58.0 | 6.00e-01 | 84.4% | 95.0% |
| 3700115 | 192.8.1.310 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › Enkurin | 0.75 | 64.0 | 5.30e-01 | 96.9% | 54.5% |
| 3599454 | 3922.1.1.132 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Enkurin | 0.74 | 64.0 | 5.28e-01 | 96.9% | 54.5% |
| 4030233 | 603.1.1.6 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin_2 | 0.73 | 63.0 | 4.51e-01 | 98.4% | 64.6% |
| 4947824 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.73 | 63.0 | 5.38e-01 | 98.4% | 60.0% |
| 3880637 | 3755.3.1.465 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A | 0.73 | 62.0 | 4.93e-01 | 100.0% | 60.7% |
| 3736652 | 192.29.1.102 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Fung_rhodopsin | 0.70 | 59.0 | 5.54e-01 | 95.3% | 81.2% |
| 3775580 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.69 | 55.0 | 5.33e-01 | 90.6% | 85.3% |
| 4542879 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.68 | 57.0 | 4.49e-01 | 96.9% | 44.1% |
D2
medium
residues 65-120
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02694.22 best | UPF0060 | 59.6 | 4.50e-16 | 94.6% | 46.7% |
CATH (44)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3lxzB02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.76 | 67.0 | 4.98e-01 | 100.0% | 39.9% |
| 3r2qA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.76 | 67.0 | 5.32e-01 | 100.0% | 54.0% |
| 4fvmA06 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.76 | 59.0 | 6.24e-01 | 83.9% | 100.0% |
| 4id0A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.76 | 65.0 | 5.27e-01 | 100.0% | 51.8% |
| 1p49A02 | 1.10.287.550 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.75 | 64.0 | 6.29e-01 | 94.6% | 89.8% |
| 4iloA00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.74 | 66.0 | 4.29e-01 | 100.0% | 25.4% |
| 5z7qA00 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.74 | 64.0 | 4.54e-01 | 100.0% | 50.0% |
| 2c2aA01 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.74 | 64.0 | 5.48e-01 | 100.0% | 61.1% |
| 1vq8V00 | 1.10.287.310 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.74 | 61.0 | 5.88e-01 | 96.4% | 81.5% |
| 6yz2A01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.73 | 66.0 | 5.08e-01 | 100.0% | 56.7% |
| 4w4kA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.73 | 62.0 | 5.48e-01 | 94.6% | 97.6% |
| 4gltA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.73 | 63.0 | 5.08e-01 | 100.0% | 86.8% |
| 4fxdA04 | 3.90.1600.10 | Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain | 0.73 | 63.0 | 4.65e-01 | 100.0% | 62.1% |
| 3hwcA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.72 | 58.0 | 4.01e-01 | 94.6% | 32.9% |
| 3cbuA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.71 | 61.0 | 4.68e-01 | 100.0% | 45.5% |
| 3qavA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.70 | 61.0 | 4.58e-01 | 100.0% | 67.9% |
| 3ousA00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.70 | 60.0 | 5.40e-01 | 100.0% | 96.3% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.70 | 58.0 | 5.06e-01 | 92.9% | 91.8% |
| 3okqA00 | 1.20.58.1540 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain | 0.70 | 56.0 | 4.50e-01 | 94.6% | 46.4% |
| 2yf4F00 | 1.10.3420.10 | Mainly Alpha › Orthogonal Bundle › putative ntp pyrophosphohydrolase like fold › putative ntp pyrophosphohydrolase like domain | 0.70 | 56.0 | 4.26e-01 | 92.9% | 39.2% |
| 3icxA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.69 | 60.0 | 5.49e-01 | 100.0% | 97.3% |
| 1e52A00 | 4.10.860.10 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain | 0.69 | 53.0 | 5.31e-01 | 94.6% | 85.7% |
| 1z5zA02 | 1.20.120.850 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SWI2/SNF2 ATPases, N-terminal domain | 0.69 | 52.0 | 4.66e-01 | 85.7% | 59.2% |
| 3l1nA01 | 6.10.140.790 | Special › Helix non-globular › Helix Hairpins › | 0.68 | 54.0 | 5.53e-01 | 92.9% | 98.0% |
| 2y1vA04 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.68 | 59.0 | 4.13e-01 | 100.0% | 35.7% |
| 2yevA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.68 | 54.0 | 5.02e-01 | 100.0% | 67.6% |
| 2wvxA04 | 1.20.1610.10 | Mainly Alpha › Up-down Bundle › Glycosyl hydrolase family fold › alpha-1,2-mannosidases domains | 0.68 | 58.0 | 4.16e-01 | 100.0% | 62.4% |
| 1gnlA01 | 1.20.1270.20 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.67 | 56.0 | 4.24e-01 | 96.4% | 71.9% |
| 3ayhA00 | 1.20.1250.40 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › RNA Polymerase II, Rpb4 subunit | 0.67 | 55.0 | 4.31e-01 | 98.2% | 88.8% |
| 5fhiA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.67 | 55.0 | 4.27e-01 | 100.0% | 71.9% |
| 3u3iA02 | 1.20.58.1110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 54.0 | 4.44e-01 | 92.9% | 51.9% |
| 2zueA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.66 | 56.0 | 4.46e-01 | 98.2% | 46.2% |
| 1rv2D04 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.65 | 53.0 | 5.03e-01 | 94.6% | 90.0% |
| 2kp8A00 | 1.20.5.170 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.64 | 55.0 | 5.15e-01 | 100.0% | 80.6% |
| 3txsC01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.64 | 50.0 | 4.69e-01 | 92.9% | 70.7% |
| 1a0aA00 | 4.10.280.10 | Few Secondary Structures › Irregular › MYOD Basic-Helix-Loop-Helix Domain, subunit B › Helix-loop-helix DNA-binding domain | 0.63 | 38.0 | 3.65e-01 | 76.8% | 50.8% |
| 2lpeA01 | 6.10.140.1120 | Special › Helix non-globular › Helix Hairpins › | 0.63 | 54.0 | 4.94e-01 | 100.0% | 82.1% |
| 2k9pA00 | 1.10.287.920 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Pheromone alpha factor receptor. | 0.63 | 49.0 | 4.47e-01 | 89.3% | 66.3% |
| 6ne6A01 | 1.10.400.10 | Mainly Alpha › Orthogonal Bundle › GI Alpha 1, domain 2-like › GI Alpha 1, domain 2-like | 0.62 | 49.0 | 4.02e-01 | 91.1% | 46.5% |
| 1u00A02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.60 | 49.0 | 4.21e-01 | 94.6% | 63.5% |
| 2e9xA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 46.0 | 3.79e-01 | 100.0% | 65.6% |
| 5lnkA00 | 1.20.58.1610 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 | 0.56 | 44.0 | 3.68e-01 | 94.6% | 53.0% |
| 2e62A01 | 6.10.140.420 | Special › Helix non-globular › Helix Hairpins › | 0.55 | 41.0 | 4.28e-01 | 82.1% | 86.5% |
| 1jt6A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.50 | 43.0 | 3.26e-01 | 96.4% | 85.4% |
ECOD (54)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3941722 | 5059.1.1.18 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › UPF0060 | 1.00 | 84.0 | 6.42e-01 | 87.5% | 44.5% |
| 4269155 | 5059.1.1.18 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › UPF0060 | 0.96 | 83.0 | 6.63e-01 | 91.1% | 51.0% |
| 4515233 | 5059.1.1.18 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › UPF0060 | 0.94 | 83.0 | 6.40e-01 | 92.9% | 47.3% |
| 4957468 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.89 | 72.0 | 5.64e-01 | 89.3% | 44.5% |
| 4078998 | 5059.1.1.2 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Multi_Drug_Res | 0.87 | 74.0 | 5.90e-01 | 92.9% | 49.5% |
| 4947726 | 5059.1.1.0 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter | 0.86 | 74.0 | 6.28e-01 | 94.6% | 58.9% |
| 3339474 | 5059.1.1.8 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Mg_trans_NIPA | 0.86 | 73.0 | 5.53e-01 | 100.0% | 41.6% |
| 3451334 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.85 | 67.0 | 6.07e-01 | 87.5% | 64.0% |
| 5052505 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.84 | 69.0 | 5.98e-01 | 92.9% | 58.8% |
| 4379654 | 633.13.1.1 ↗ | alpha bundles › Bromodomain-like › DsbB-like › DsbB-like › DsbB | 0.83 | 71.0 | 5.02e-01 | 94.6% | 34.5% |
| 3573978 | 5059.1.1.11 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › TMEM144 | 0.82 | 67.0 | 4.89e-01 | 91.1% | 37.3% |
| 5016588 | 5059.1.1.0 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter | 0.81 | 61.0 | 4.58e-01 | 82.1% | 34.1% |
| 3929097 | 4163.1.1.0 ↗ | alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like | 0.81 | 69.0 | 5.21e-01 | 94.6% | 42.3% |
| 5051879 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.79 | 67.0 | 6.10e-01 | 94.6% | 78.7% |
| 4962504 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.79 | 67.0 | 6.07e-01 | 94.6% | 78.7% |
| 3229947 | 5001.1.1.84 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srz | 0.79 | 68.0 | 4.27e-01 | 100.0% | 68.4% |
| 3502362 | 601.54.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › low CO2-inducible protein LCI1 › low CO2-inducible protein LCI1 › MTABC_N | 0.77 | 64.0 | 4.44e-01 | 92.9% | 29.7% |
| 5040175 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.76 | 63.0 | 5.03e-01 | 94.6% | 51.3% |
| 5050359 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.76 | 66.0 | 6.20e-01 | 100.0% | 91.4% |
| 5049840 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.75 | 61.0 | 5.60e-01 | 94.6% | 68.0% |
| 3684478 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.75 | 64.0 | 5.98e-01 | 100.0% | 78.6% |
| 5044800 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.75 | 61.0 | 5.44e-01 | 94.6% | 63.7% |
| 3925082 | 5059.1.1.5 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › UAA | 0.75 | 66.0 | 4.21e-01 | 100.0% | 21.1% |
| 3857880 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.74 | 63.0 | 4.77e-01 | 100.0% | 60.0% |
| 5050356 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.74 | 62.0 | 5.81e-01 | 94.6% | 84.3% |
| 3476880 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.74 | 60.0 | 4.18e-01 | 92.9% | 28.5% |
| 5041271 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.74 | 65.0 | 5.93e-01 | 100.0% | 84.0% |
| 3695151 | 3722.1.1.5 ↗ | alpha bundles › Protein regulator of cytokinesis 1 (PRC1) rod domain › Protein regulator of cytokinesis 1 (PRC1) rod domain › Protein regulator of cytokinesis 1 (PRC1) rod domain › AIP3 | 0.74 | 60.0 | 3.95e-01 | 94.6% | 22.7% |
| 5002748 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.74 | 64.0 | 5.85e-01 | 100.0% | 85.3% |
| 3674753 | 192.1.1.23 ↗ | alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › DUF3493 | 0.74 | 66.0 | 6.11e-01 | 100.0% | 90.0% |
| 3965569 | 150.1.1.183 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Transposase_20 | 0.74 | 65.0 | 4.53e-01 | 100.0% | 44.4% |
| 3731867 | 3758.1.1.34 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins › AIP3 | 0.73 | 60.0 | 3.85e-01 | 94.6% | 20.0% |
| 4119921 | 1128.1.1.23 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › Ycf66_N | 0.73 | 60.0 | 5.07e-01 | 92.9% | 54.3% |
| 3236284 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.73 | 63.0 | 5.65e-01 | 100.0% | 76.2% |
| 4929436 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.72 | 58.0 | 5.24e-01 | 94.6% | 63.7% |
| 3737907 | 192.29.1.153 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › AIP3 | 0.72 | 58.0 | 4.14e-01 | 94.6% | 31.4% |
| 2323907 | 212.1.1.24 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Morc6_S5 | 0.71 | 59.0 | 3.86e-01 | 94.6% | 22.5% |
| 4031537 | 159.1.2.0 ↗ | alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related | 0.71 | 58.0 | 4.93e-01 | 94.6% | 56.0% |
| 3603032 | 622.1.1.0 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain | 0.71 | 56.0 | 4.90e-01 | 89.3% | 57.6% |
| 4854384 | 5039.1.1.1 ↗ | alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › COX3 | 0.70 | 60.0 | 5.05e-01 | 100.0% | 55.4% |
| 4024514 | 5059.1.1.8 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Mg_trans_NIPA | 0.70 | 57.0 | 4.54e-01 | 94.6% | 44.3% |
| 3373714 | 3755.4.1.17 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Rx_N | 0.70 | 56.0 | 4.33e-01 | 94.6% | 44.3% |
| 3922358 | 3560.1.1.1 ↗ | a+b complex topology › Mediator of RNA polymerase II transcription subunit 8 › Mediator of RNA polymerase II transcription subunit 8 › Mediator of RNA polymerase II transcription subunit 8 › Med8 | 0.70 | 59.0 | 4.28e-01 | 100.0% | 35.3% |
| 4055322 | 3560.1.1.1 ↗ | a+b complex topology › Mediator of RNA polymerase II transcription subunit 8 › Mediator of RNA polymerase II transcription subunit 8 › Mediator of RNA polymerase II transcription subunit 8 › Med8 | 0.70 | 60.0 | 4.21e-01 | 100.0% | 32.4% |
| 3926271 | 174.1.1.56 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › TMD0_ABC | 0.69 | 60.0 | 4.13e-01 | 100.0% | 74.4% |
| 4142346 | 5086.1.1.87 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING | 0.69 | 59.0 | 4.82e-01 | 100.0% | 53.6% |
| 5001606 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.67 | 58.0 | 4.37e-01 | 100.0% | 39.3% |
| 3491418 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.66 | 55.0 | 5.14e-01 | 100.0% | 82.7% |
| 4982292 | 5045.1.1.0 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A | 0.65 | 57.0 | 3.83e-01 | 100.0% | 24.9% |
| 5050578 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.65 | 55.0 | 4.98e-01 | 98.2% | 93.8% |
| 4437398 | 160.1.1.1 ↗ | alpha superhelices › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase › ATP-synt_ab_C | 0.64 | 48.0 | 3.64e-01 | 80.4% | 34.8% |
| 4436455 | 7022.1.1.1 ↗ | alpha bundles › central core domain of D-alanyl transfer protein › central core domain of D-alanyl transfer protein › central core domain of D-alanyl transfer protein › MBOAT | 0.63 | 52.0 | 3.20e-01 | 100.0% | 14.5% |
| 3241767 | 109.4.1.343 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RAB3GAP2_C | 0.62 | 50.0 | 3.00e-01 | 92.9% | 25.5% |
| 4946512 | 7516.1.1.2 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 | 0.62 | 47.0 | 3.04e-01 | 92.9% | 87.3% |