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CAKLQH020000047.1__CAH1096024.1__SAMEA5780036_03813__00007
Bact-VirCAKLQH020000047.1__CAH1096024.1__SAMEA5780036_03813__00007
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 93-150
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF25181.2 best | Phage_Bbp19 | 30.2 | 4.60e-07 | 93.1% | 80.3% |
CATH (48)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7nc3F01 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.77 | 59.0 | 4.78e-01 | 84.5% | 51.8% |
| 6h9xA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.77 | 60.0 | 5.03e-01 | 86.2% | 76.5% |
| 3fxdC00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.74 | 58.0 | 6.15e-01 | 87.9% | 100.0% |
| 8cdaB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.70 | 58.0 | 4.23e-01 | 91.4% | 52.8% |
| 1s35A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 53.0 | 4.45e-01 | 84.5% | 49.5% |
| 1ku9A02 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.69 | 55.0 | 5.37e-01 | 89.7% | 98.4% |
| 1zoyA03 | 1.20.58.100 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain | 0.68 | 51.0 | 4.08e-01 | 86.2% | 40.2% |
| 3txsC01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.68 | 55.0 | 5.11e-01 | 91.4% | 74.7% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.68 | 56.0 | 4.78e-01 | 96.6% | 88.2% |
| 2l3lA01 | 1.20.58.1250 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain | 0.68 | 55.0 | 4.52e-01 | 91.4% | 49.1% |
| 3icxA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.67 | 58.0 | 5.37e-01 | 98.3% | 80.0% |
| 3oftA00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.67 | 50.0 | 3.03e-01 | 86.2% | 11.9% |
| 2nwlC00 | 1.10.3860.10 | Mainly Alpha › Orthogonal Bundle › Proton glutamate symport protein › Sodium:dicarboxylate symporter | 0.66 | 55.0 | 3.39e-01 | 98.3% | 35.2% |
| 4dciA00 | 6.10.140.1110 | Special › Helix non-globular › Helix Hairpins › | 0.65 | 55.0 | 4.16e-01 | 96.6% | 60.5% |
| 1b3qA01 | 1.10.287.560 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Histidine kinase CheA-like, homodimeric domain | 0.65 | 57.0 | 5.59e-01 | 98.3% | 96.8% |
| 3okqA00 | 1.20.58.1540 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain | 0.65 | 45.0 | 3.60e-01 | 74.1% | 72.8% |
| 4z5qA00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.65 | 44.0 | 2.70e-01 | 70.7% | 13.2% |
| 3fxdB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 52.0 | 5.21e-01 | 91.4% | 96.6% |
| 3hr0B01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.64 | 51.0 | 4.73e-01 | 91.4% | 100.0% |
| 2kp8A00 | 1.20.5.170 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.63 | 45.0 | 4.27e-01 | 77.6% | 81.9% |
| 4gzrC00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.63 | 49.0 | 4.90e-01 | 86.2% | 93.4% |
| 3favD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.63 | 52.0 | 4.74e-01 | 93.1% | 100.0% |
| 3lphC00 | 6.10.140.630 | Special › Helix non-globular › Helix Hairpins › | 0.63 | 51.0 | 5.14e-01 | 91.4% | 100.0% |
| 1wpaA01 | 6.10.140.340 | Special › Helix non-globular › Helix Hairpins › | 0.63 | 52.0 | 4.46e-01 | 96.6% | 100.0% |
| 1skvA00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.63 | 51.0 | 4.95e-01 | 91.4% | 92.2% |
| 1xjaB00 | 2.60.120.280 | Mainly Beta › Sandwich › Jelly Rolls › Regulatory protein AraC | 0.62 | 46.0 | 3.50e-01 | 86.2% | 31.2% |
| 1m62A00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.62 | 52.0 | 4.70e-01 | 100.0% | 70.1% |
| 3l1nA01 | 6.10.140.790 | Special › Helix non-globular › Helix Hairpins › | 0.62 | 48.0 | 4.97e-01 | 91.4% | 98.0% |
| 3eabE00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.62 | 51.0 | 4.56e-01 | 94.8% | 77.9% |
| 1u7lA02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.62 | 53.0 | 3.80e-01 | 100.0% | 96.2% |
| 4ivfA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.62 | 50.0 | 4.06e-01 | 91.4% | 45.7% |
| 1ij5A01 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 49.0 | 4.52e-01 | 91.4% | 68.4% |
| 6r1nA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.61 | 48.0 | 4.10e-01 | 93.1% | 51.5% |
| 3ay5A01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.61 | 51.0 | 4.06e-01 | 100.0% | 48.1% |
| 4w4kA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.61 | 49.0 | 4.43e-01 | 91.4% | 65.9% |
| 7jv7B01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.60 | 52.0 | 3.93e-01 | 100.0% | 93.2% |
| 3h6pC00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.60 | 42.0 | 4.31e-01 | 75.9% | 100.0% |
| 1wleA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.60 | 48.0 | 4.04e-01 | 96.6% | 55.3% |
| 2rkhA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.59 | 48.0 | 4.50e-01 | 96.6% | 85.5% |
| 2i7uA00 | 6.10.250.1010 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.59 | 46.0 | 4.59e-01 | 91.4% | 83.9% |
| 3m1cB01 | 3.30.390.170 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › | 0.59 | 50.0 | 4.10e-01 | 96.6% | 54.1% |
| 2lpeA01 | 6.10.140.1120 | Special › Helix non-globular › Helix Hairpins › | 0.59 | 50.0 | 4.60e-01 | 100.0% | 94.9% |
| 2fb5A01 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.58 | 49.0 | 4.61e-01 | 98.3% | 87.5% |
| 2eqyA01 | 1.10.150.60 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › ARID DNA-binding domain | 0.58 | 44.0 | 3.70e-01 | 87.9% | 71.4% |
| 2b5dX01 | 3.20.110.10 | Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain | 0.58 | 48.0 | 2.93e-01 | 96.6% | 20.3% |
| 3fd9A03 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.57 | 47.0 | 4.48e-01 | 98.3% | 82.2% |
| 3v5uA01 | 6.10.280.80 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region | 0.57 | 46.0 | 4.38e-01 | 100.0% | 75.0% |
| 1x42A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.50 | 43.0 | 3.87e-01 | 98.3% | 81.9% |
ECOD (41)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4136151 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.73 | 56.0 | 4.73e-01 | 84.5% | 53.0% |
| 4819006 | 2004.1.1.5 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran | 0.71 | 59.0 | 3.75e-01 | 93.1% | 19.4% |
| 3382610 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.70 | 55.0 | 3.50e-01 | 84.5% | 42.2% |
| 3927738 | 632.8.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 | 0.70 | 54.0 | 4.66e-01 | 86.2% | 85.3% |
| 4043979 | 3812.1.1.4 ↗ | alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE › GrpE | 0.69 | 54.0 | 5.41e-01 | 91.4% | 86.7% |
| 4174058 | 3922.1.1.154 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › GrpE | 0.69 | 54.0 | 4.48e-01 | 91.4% | 47.3% |
| 4493879 | 4992.1.1.23 ↗ | extended segments › RelB-like › RelB-like › RelB-like › Seryl_tRNA_N | 0.69 | 52.0 | 4.35e-01 | 86.2% | 81.8% |
| 4177674 | 4992.1.1.23 ↗ | extended segments › RelB-like › RelB-like › RelB-like › Seryl_tRNA_N | 0.68 | 51.0 | 4.26e-01 | 84.5% | 70.9% |
| 3516452 | 378.1.1.0 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases | 0.68 | 55.0 | 3.68e-01 | 89.7% | 29.1% |
| 3934599 | 603.2.1.0 ↗ | alpha bundles › STAT-like › STAT › STAT | 0.68 | 58.0 | 4.87e-01 | 100.0% | 65.7% |
| 4090297 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.67 | 51.0 | 4.32e-01 | 86.2% | 88.6% |
| 5057549 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.67 | 51.0 | 4.11e-01 | 84.5% | 45.8% |
| 4182426 | 192.6.1.2 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain › ATPD_C_fung | 0.67 | 49.0 | 5.18e-01 | 91.4% | 97.9% |
| 3663959 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.66 | 53.0 | 4.18e-01 | 91.4% | 67.7% |
| 5012794 | 4333.1.1.0 ↗ | a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain | 0.66 | 50.0 | 3.11e-01 | 84.5% | 15.2% |
| 5017743 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.66 | 48.0 | 4.35e-01 | 81.0% | 82.4% |
| 3181110 | 5086.1.1.110 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HisKA | 0.66 | 52.0 | 4.54e-01 | 91.4% | 89.5% |
| 4474737 | 3711.1.1.44 ↗ | alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › Med11 | 0.65 | 49.0 | 4.34e-01 | 84.5% | 78.9% |
| 3167298 | 3711.1.1.0 ↗ | alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein | 0.65 | 54.0 | 4.49e-01 | 93.1% | 97.1% |
| 3349325 | 5086.1.1.135 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › DUF7615 | 0.65 | 52.0 | 4.76e-01 | 91.4% | 75.0% |
| 4596937 | 605.1.1.247 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › PCRF | 0.64 | 48.0 | 4.13e-01 | 84.5% | 52.0% |
| 3394753 | 192.5.1.12 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › PH_19 | 0.64 | 52.0 | 4.94e-01 | 93.1% | 92.9% |
| 1106555 | 3812.1.1.1 ↗ | alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE › T3SS_needle_E | 0.64 | 54.0 | 5.22e-01 | 96.6% | 86.4% |
| 3629047 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.64 | 48.0 | 4.10e-01 | 84.5% | 54.0% |
| 3810801 | 632.22.1.139 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › KIF21A_4th | 0.63 | 51.0 | 3.88e-01 | 96.6% | 36.0% |
| 3264360 | 4995.1.1.0 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like | 0.63 | 54.0 | 3.98e-01 | 100.0% | 50.3% |
| 3855328 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.63 | 49.0 | 4.32e-01 | 91.4% | 58.9% |
| 3971315 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.63 | 48.0 | 4.14e-01 | 89.7% | 50.5% |
| 4579811 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.62 | 47.0 | 4.02e-01 | 86.2% | 86.7% |
| 4878766 | 1075.4.1.9 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_tran+ABC_membrane | 0.62 | 51.0 | 4.13e-01 | 98.3% | 47.2% |
| 3218879 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.62 | 48.0 | 4.84e-01 | 93.1% | 88.3% |
| 3754639 | 150.5.1.106 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › LIN9_C | 0.62 | 49.0 | 4.44e-01 | 93.1% | 82.4% |
| 3477418 | 4992.1.1.12 ↗ | extended segments › RelB-like › RelB-like › RelB-like › LIN9_C | 0.62 | 51.0 | 4.42e-01 | 96.6% | 67.4% |
| 3256598 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.62 | 49.0 | 4.30e-01 | 93.1% | 62.1% |
| 4054880 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.61 | 47.0 | 4.04e-01 | 89.7% | 50.5% |
| 4943813 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.61 | 47.0 | 3.76e-01 | 87.9% | 40.8% |
| 4039320 | 192.1.1.2 ↗ | alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › GreA_GreB_N | 0.60 | 50.0 | 4.63e-01 | 100.0% | 87.5% |
| 3840952 | 601.19.1.39 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › LIN9_C | 0.60 | 46.0 | 4.34e-01 | 89.7% | 98.7% |
| 2485668 | 7025.1.1.2 ↗ | alpha bundles › LIN9-LIN52 heterodimer › LIN9-LIN52 heterodimer › LIN9-LIN52 heterodimer › LIN9_C | 0.60 | 47.0 | 4.30e-01 | 93.1% | 75.0% |
| 4937093 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.57 | 47.0 | 3.84e-01 | 98.3% | 68.3% |
| 223738 | 3602.1.1.1 ↗ | alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › SAM_KSR1_N | 0.56 | 43.0 | 4.18e-01 | 91.4% | 81.4% |
D2
medium
residues 14-87
Domain cluster:
representative