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CAKLQH020000047.1__CAH1096040.1__SAMEA5780036_03821__00015
Bact-VirCAKLQH020000047.1__CAH1096040.1__SAMEA5780036_03821__00015
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 30-110
Domain cluster:
rep: MG592548.1__AUR93056.1__NVP1182O_14__00014__D36-122
CATH (70)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5wp3B00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.83 | 66.0 | 6.07e-01 | 95.1% | 66.7% |
| 4l8iB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.82 | 65.0 | 5.77e-01 | 91.4% | 60.7% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.79 | 69.0 | 6.10e-01 | 96.3% | 66.7% |
| 2uv8A07 | 6.10.140.1410 | Special › Helix non-globular › Helix Hairpins › | 0.78 | 66.0 | 6.55e-01 | 92.6% | 92.9% |
| 2x2vA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.76 | 59.0 | 6.32e-01 | 85.2% | 98.5% |
| 2vkzA02 | 3.40.47.10 | Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase | 0.76 | 68.0 | 4.74e-01 | 100.0% | 47.7% |
| 1dn1B00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.75 | 55.0 | 3.94e-01 | 81.5% | 27.9% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.74 | 66.0 | 5.61e-01 | 100.0% | 61.7% |
| 4w4kA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.73 | 64.0 | 6.37e-01 | 100.0% | 92.7% |
| 1t72A02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.73 | 59.0 | 5.50e-01 | 98.8% | 71.4% |
| 1tjlA00 | 1.20.120.910 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain | 0.72 | 52.0 | 4.18e-01 | 76.5% | 41.4% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.71 | 58.0 | 4.90e-01 | 87.7% | 100.0% |
| 4gzrB00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.70 | 58.0 | 5.93e-01 | 100.0% | 93.5% |
| 8a1gC01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.70 | 61.0 | 4.80e-01 | 100.0% | 56.4% |
| 2gl2B00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.70 | 56.0 | 5.05e-01 | 85.2% | 67.0% |
| 3l39A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.70 | 54.0 | 4.08e-01 | 84.0% | 69.0% |
| 3qweA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.70 | 63.0 | 4.37e-01 | 100.0% | 76.5% |
| 3ofnY00 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.69 | 61.0 | 5.48e-01 | 100.0% | 74.8% |
| 2rdcA00 | 1.10.287.800 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 | 0.69 | 55.0 | 4.66e-01 | 96.3% | 52.6% |
| 3rh3A01 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.69 | 60.0 | 5.14e-01 | 98.8% | 94.0% |
| 3ok8A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.68 | 62.0 | 4.50e-01 | 100.0% | 64.8% |
| 3k29A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.68 | 62.0 | 4.90e-01 | 100.0% | 83.2% |
| 2lm9A00 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 50.0 | 4.73e-01 | 93.8% | 65.6% |
| 1zpyA00 | 6.10.140.1960 | Special › Helix non-globular › Helix Hairpins › | 0.68 | 48.0 | 4.63e-01 | 74.1% | 64.8% |
| 2oexA02 | 1.20.140.50 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › alix/aip1 like domains | 0.68 | 57.0 | 4.22e-01 | 90.1% | 83.2% |
| 3lnnB03 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.68 | 49.0 | 5.29e-01 | 81.5% | 91.0% |
| 3mq1A01 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 50.0 | 4.78e-01 | 97.5% | 67.4% |
| 4yjwA00 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.68 | 59.0 | 4.87e-01 | 100.0% | 93.5% |
| 3fppA03 | 6.10.140.1990 | Special › Helix non-globular › Helix Hairpins › | 0.68 | 60.0 | 5.83e-01 | 98.8% | 88.6% |
| 3g67A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.67 | 61.0 | 4.45e-01 | 100.0% | 37.6% |
| 3cwzB01 | 1.20.58.900 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain | 0.67 | 50.0 | 4.05e-01 | 80.2% | 42.5% |
| 4abmD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.67 | 55.0 | 5.68e-01 | 95.1% | 93.5% |
| 1vf7A03 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.67 | 46.0 | 5.27e-01 | 86.4% | 96.7% |
| 2dw4A03 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.67 | 54.0 | 5.04e-01 | 100.0% | 70.3% |
| 1b5lA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.66 | 49.0 | 4.01e-01 | 79.0% | 68.4% |
| 1i6zA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.66 | 53.0 | 4.51e-01 | 91.4% | 52.6% |
| 1uruA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.66 | 59.0 | 4.41e-01 | 100.0% | 38.8% |
| 3zdqA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.66 | 54.0 | 3.52e-01 | 87.7% | 40.8% |
| 3hr0B01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.66 | 55.0 | 5.64e-01 | 93.8% | 93.7% |
| 4q4hA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.66 | 60.0 | 3.96e-01 | 100.0% | 28.6% |
| 2uuiA00 | 1.20.120.550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain | 0.65 | 56.0 | 4.58e-01 | 96.3% | 81.9% |
| 1t72A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.65 | 55.0 | 4.88e-01 | 96.3% | 65.0% |
| 1k04A02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.65 | 56.0 | 5.19e-01 | 95.1% | 76.0% |
| 1ydxA02 | 1.10.287.1120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein | 0.65 | 54.0 | 5.20e-01 | 100.0% | 81.1% |
| 1st6A04 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.65 | 51.0 | 4.48e-01 | 86.4% | 58.1% |
| 2ch7A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.65 | 58.0 | 3.89e-01 | 100.0% | 36.9% |
| 2lw1A00 | 1.10.287.380 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain | 0.64 | 49.0 | 4.87e-01 | 87.7% | 77.6% |
| 6grjB01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.64 | 57.0 | 3.84e-01 | 100.0% | 57.1% |
| 3vbbE01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.64 | 57.0 | 5.00e-01 | 98.8% | 97.5% |
| 4h63K00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.63 | 50.0 | 4.72e-01 | 93.8% | 70.4% |
| 2wbiB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.63 | 52.0 | 4.22e-01 | 97.5% | 46.8% |
| 4ysxC00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.63 | 52.0 | 4.34e-01 | 95.1% | 51.6% |
| 1rx0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.62 | 49.0 | 3.94e-01 | 84.0% | 45.2% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.62 | 48.0 | 5.19e-01 | 85.2% | 100.0% |
| 2q0oC00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.62 | 48.0 | 4.76e-01 | 90.1% | 79.1% |
| 3icxA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.62 | 52.0 | 5.39e-01 | 90.1% | 100.0% |
| 2dnxA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 49.0 | 4.20e-01 | 90.1% | 53.8% |
| 2dq0A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.62 | 55.0 | 5.02e-01 | 98.8% | 97.2% |
| 2xubA05 | 6.10.140.1450 | Special › Helix non-globular › Helix Hairpins › | 0.61 | 55.0 | 5.21e-01 | 100.0% | 95.8% |
| 1hs7A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 45.0 | 4.23e-01 | 85.2% | 64.9% |
| 1h7cA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 49.0 | 4.49e-01 | 86.4% | 79.6% |
| 4xvxA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.60 | 50.0 | 4.15e-01 | 92.6% | 92.5% |
| 3rlfF01 | 1.20.58.370 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › MalF N-terminal region-like | 0.59 | 40.0 | 3.93e-01 | 80.2% | 65.1% |
| 1uurA01 | 1.20.58.240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 | 0.59 | 49.0 | 4.42e-01 | 95.1% | 66.4% |
| 3lbxB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 47.0 | 4.29e-01 | 87.7% | 66.4% |
| 7zxkC01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.57 | 47.0 | 3.84e-01 | 90.1% | 100.0% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.57 | 47.0 | 4.12e-01 | 90.1% | 65.3% |
| 8b6jF01 | 1.10.287.20 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Ubiquinol-cytochrome C reductase hinge domain | 0.56 | 39.0 | 4.23e-01 | 80.2% | 91.0% |
| 3ihuA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.54 | 42.0 | 3.53e-01 | 82.7% | 65.5% |
| 1br0A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 44.0 | 3.95e-01 | 100.0% | 63.3% |
ECOD (93)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5063536 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.90 | 68.0 | 6.27e-01 | 84.0% | 64.0% |
| 5027916 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.88 | 67.0 | 5.96e-01 | 79.0% | 58.2% |
| 3839085 | 5058.1.1.2 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st | 0.87 | 66.0 | 6.11e-01 | 84.0% | 64.0% |
| 4965867 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.87 | 65.0 | 6.32e-01 | 84.0% | 71.1% |
| 5065662 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.86 | 62.0 | 6.72e-01 | 76.5% | 87.1% |
| 4942626 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.86 | 64.0 | 5.91e-01 | 77.8% | 63.0% |
| 5033072 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.85 | 64.0 | 5.49e-01 | 84.0% | 52.0% |
| 4949270 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.85 | 65.0 | 5.78e-01 | 86.4% | 59.1% |
| 4984270 | 4.1.1.481 ↗ | beta barrels › SH3 › SH3 › SH3 › MS_channel_1st_1 | 0.85 | 62.0 | 5.74e-01 | 81.5% | 62.0% |
| 3974187 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.84 | 62.0 | 5.98e-01 | 84.0% | 68.9% |
| 4237056 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.84 | 78.0 | 6.37e-01 | 100.0% | 59.3% |
| 5050114 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.84 | 63.0 | 6.11e-01 | 84.0% | 71.1% |
| 5043090 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.84 | 63.0 | 6.39e-01 | 84.0% | 80.0% |
| 3717860 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.83 | 75.0 | 7.22e-01 | 100.0% | 87.8% |
| 4928060 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.83 | 62.0 | 5.54e-01 | 82.7% | 57.8% |
| 4588350 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.83 | 76.0 | 6.14e-01 | 100.0% | 54.0% |
| 3957435 | 5058.1.1.2 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st | 0.82 | 69.0 | 6.03e-01 | 98.8% | 60.8% |
| 4002301 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.82 | 75.0 | 4.65e-01 | 100.0% | 49.7% |
| 5036646 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.82 | 64.0 | 6.22e-01 | 87.7% | 74.4% |
| 3285146 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.80 | 69.0 | 6.98e-01 | 92.6% | 93.8% |
| 3398929 | 5041.1.1.32 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › TMEM141 | 0.80 | 69.0 | 6.66e-01 | 98.8% | 84.4% |
| 4928541 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.80 | 73.0 | 6.03e-01 | 100.0% | 63.8% |
| 4216519 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.77 | 62.0 | 4.26e-01 | 90.1% | 26.4% |
| 4238120 | 195.1.1.1 ↗ | alpha complex topology › NusB-like › NusB-like › NusB-like › NusB | 0.76 | 54.0 | 3.93e-01 | 74.1% | 28.8% |
| 3313165 | 3559.1.1.34 ↗ | a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Oleosin | 0.75 | 64.0 | 5.60e-01 | 100.0% | 61.6% |
| 4564044 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.75 | 59.0 | 4.13e-01 | 90.1% | 26.5% |
| 3958129 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.75 | 68.0 | 6.68e-01 | 100.0% | 94.1% |
| 3484528 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.74 | 66.0 | 4.32e-01 | 98.8% | 65.7% |
| 3712635 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.74 | 60.0 | 5.75e-01 | 92.6% | 76.8% |
| 3914665 | 604.5.1.10 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › HRG | 0.73 | 61.0 | 4.98e-01 | 88.9% | 50.0% |
| 3309382 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.73 | 65.0 | 4.33e-01 | 100.0% | 71.6% |
| 4951992 | 5041.1.1.55 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › DUF1622 | 0.73 | 57.0 | 5.35e-01 | 90.1% | 68.0% |
| 3601962 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.73 | 66.0 | 4.32e-01 | 100.0% | 46.4% |
| 3596860 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.72 | 65.0 | 4.62e-01 | 100.0% | 70.4% |
| 3957973 | 150.5.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 | 0.72 | 65.0 | 6.11e-01 | 100.0% | 82.8% |
| 3616343 | 601.1.1.97 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DNA_repr_REX1B | 0.72 | 54.0 | 4.52e-01 | 82.7% | 47.4% |
| 3346986 | 3711.1.1.4 ↗ | alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › DOG1 | 0.72 | 65.0 | 4.81e-01 | 100.0% | 51.2% |
| 4940500 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.72 | 58.0 | 5.14e-01 | 87.7% | 62.6% |
| 3973899 | 5086.1.1.92 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE | 0.70 | 64.0 | 5.25e-01 | 100.0% | 76.6% |
| 3726923 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.70 | 63.0 | 5.34e-01 | 100.0% | 60.8% |
| 3402390 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.70 | 59.0 | 4.96e-01 | 91.4% | 88.9% |
| 4821107 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.70 | 59.0 | 3.90e-01 | 95.1% | 23.1% |
| 4942625 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.70 | 56.0 | 5.69e-01 | 87.7% | 90.0% |
| 3685313 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.70 | 62.0 | 4.95e-01 | 97.5% | 51.3% |
| 3962942 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.69 | 61.0 | 4.99e-01 | 100.0% | 52.7% |
| 3972622 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.69 | 62.0 | 5.74e-01 | 100.0% | 79.0% |
| 3164951 | 5094.1.1.1 ↗ | a+b duplicates or obligate multimers › OmpH-like › OmpH-like › OmpH-like › OmpH | 0.69 | 63.0 | 4.92e-01 | 100.0% | 68.8% |
| 3705838 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.69 | 57.0 | 4.13e-01 | 100.0% | 32.2% |
| 3816459 | 3684.1.1.10 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › DUF677 | 0.69 | 63.0 | 4.70e-01 | 100.0% | 94.9% |
| 3628600 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.69 | 56.0 | 4.50e-01 | 95.1% | 46.7% |
| 4250162 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.69 | 63.0 | 5.27e-01 | 100.0% | 61.5% |
| 3589462 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.69 | 58.0 | 4.30e-01 | 90.1% | 48.2% |
| 3968183 | 3758.2.1.1 ↗ | alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB | 0.68 | 61.0 | 4.92e-01 | 100.0% | 55.1% |
| 3594672 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.68 | 62.0 | 4.37e-01 | 100.0% | 53.5% |
| 3719904 | 148.1.3.13 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_9 | 0.68 | 56.0 | 3.64e-01 | 100.0% | 19.7% |
| 3935140 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.68 | 60.0 | 4.57e-01 | 100.0% | 43.3% |
| 3699787 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.68 | 60.0 | 4.29e-01 | 100.0% | 40.0% |
| 4642325 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.68 | 61.0 | 5.20e-01 | 100.0% | 82.3% |
| 3596280 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.67 | 58.0 | 4.17e-01 | 96.3% | 57.9% |
| 4444553 | 7516.1.1.2 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 | 0.67 | 58.0 | 3.81e-01 | 100.0% | 23.4% |
| 3184584 | 603.1.1.100 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27017 | 0.67 | 62.0 | 5.16e-01 | 100.0% | 60.0% |
| 3967398 | 3755.1.1.1 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › YscO | 0.67 | 61.0 | 4.94e-01 | 100.0% | 54.7% |
| 3386973 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.66 | 59.0 | 5.69e-01 | 100.0% | 87.8% |
| 3184140 | 5086.1.1.87 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING | 0.66 | 59.0 | 5.25e-01 | 100.0% | 84.3% |
| 3971026 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.65 | 57.0 | 5.03e-01 | 100.0% | 84.8% |
| 3373648 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.65 | 55.0 | 4.50e-01 | 91.4% | 84.1% |
| 5065235 | 101.1.2.738 ↗ | alpha arrays › HTH › HTH › winged helix domain › Vir_act_alpha_C | 0.65 | 57.0 | 4.38e-01 | 98.8% | 42.7% |
| 3504301 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.65 | 52.0 | 4.71e-01 | 100.0% | 63.6% |
| 3699463 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.65 | 59.0 | 4.29e-01 | 100.0% | 40.0% |
| 3875112 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.64 | 59.0 | 3.84e-01 | 100.0% | 27.6% |
| 3692474 | 5059.1.1.0 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter | 0.64 | 56.0 | 4.58e-01 | 95.1% | 55.9% |
| 3608194 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.64 | 57.0 | 4.25e-01 | 100.0% | 66.3% |
| 3711883 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.64 | 58.0 | 4.21e-01 | 98.8% | 81.9% |
| 4145392 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.64 | 52.0 | 3.81e-01 | 91.4% | 32.6% |
| 3485540 | 603.1.1.1 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin | 0.64 | 55.0 | 4.20e-01 | 91.4% | 43.4% |
| 5005097 | 3710.1.1.0 ↗ | alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain | 0.64 | 58.0 | 4.89e-01 | 100.0% | 91.7% |
| 3593643 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.64 | 57.0 | 4.27e-01 | 98.8% | 87.7% |
| 3513364 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.64 | 52.0 | 4.29e-01 | 90.1% | 83.3% |
| 3493417 | 4163.1.1.1 ↗ | alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5 | 0.63 | 57.0 | 4.55e-01 | 100.0% | 50.6% |
| 2886939 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.63 | 57.0 | 3.78e-01 | 100.0% | 28.4% |
| 4564236 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.62 | 56.0 | 4.29e-01 | 100.0% | 46.7% |
| 3297770 | 622.4.1.26 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › HisKA | 0.62 | 48.0 | 4.74e-01 | 85.2% | 80.0% |
| 3284805 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.62 | 50.0 | 4.28e-01 | 90.1% | 91.9% |
| 3282706 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.61 | 51.0 | 4.44e-01 | 95.1% | 98.5% |
| 3992828 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.61 | 52.0 | 3.88e-01 | 98.8% | 48.4% |
| 4273807 | 314.1.1.0 ↗ | a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases | 0.61 | 54.0 | 3.39e-01 | 98.8% | 78.6% |
| 4499889 | 192.24.1.1 ↗ | alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain › RPC3_helical | 0.60 | 50.0 | 4.76e-01 | 100.0% | 76.3% |
| 3972236 | 3755.3.1.42 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › CheZ | 0.60 | 54.0 | 4.18e-01 | 100.0% | 45.6% |
| 3909017 | 192.5.1.1 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1 | 0.60 | 53.0 | 5.16e-01 | 100.0% | 87.8% |
| 4076285 | 3755.1.1.12 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › CheZ | 0.60 | 53.0 | 4.46e-01 | 100.0% | 58.6% |
| 5052557 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.60 | 54.0 | 4.08e-01 | 100.0% | 58.5% |
| 5009131 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.59 | 53.0 | 4.21e-01 | 100.0% | 49.7% |
| 3609435 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.59 | 47.0 | 4.58e-01 | 88.9% | 82.2% |