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CD47-like_protein
Euk-VirDeerpox_virus_W-848-83
CD47-like_protein__YP_227513__Deerpox_virus_W-848-83__305674
Identity
- Accession:
- YP_227513 ↗
- Protein ID:
- CD47-like_protein
- Kingdom:
- euk
Quality
74.7
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Cervidpoxvirus›
Deerpox_virus_W-848-83
TaxID: 305674
Cluster
View cluster (15 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 29-117
D2
medium
residues 122-211_267-279
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04549.20 best | CD47 | 74.8 | 1.20e-20 | 90.3% | 58.5% |
CATH (41)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2okuA00 | 1.20.120.470 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Acyl-CoA dehydrogenase, C-terminal domain | 0.78 | 66.0 | 6.25e-01 | 99.0% | 76.2% |
| 2p7vA00 | 1.20.120.1370 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Regulator of RNA polymerase sigma(70) subunit, domain 4 | 0.76 | 70.0 | 6.09e-01 | 100.0% | 74.8% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.74 | 66.0 | 6.03e-01 | 100.0% | 74.6% |
| 4abmD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.74 | 49.0 | 5.60e-01 | 70.9% | 90.9% |
| 3layF00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.73 | 48.0 | 5.46e-01 | 71.8% | 88.5% |
| 4dylA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.73 | 67.0 | 4.96e-01 | 100.0% | 85.6% |
| 3na7A00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.73 | 48.0 | 3.58e-01 | 70.9% | 29.1% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.72 | 55.0 | 5.42e-01 | 80.6% | 91.8% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.72 | 48.0 | 4.41e-01 | 99.0% | 53.4% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.72 | 60.0 | 5.81e-01 | 92.2% | 95.8% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.71 | 47.0 | 4.75e-01 | 70.9% | 67.6% |
| 3rguB00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.71 | 56.0 | 5.95e-01 | 99.0% | 100.0% |
| 2m6uA00 | 1.20.81.20 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › | 0.71 | 53.0 | 5.89e-01 | 85.4% | 100.0% |
| 3qweA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.70 | 64.0 | 4.72e-01 | 100.0% | 84.2% |
| 2dq0A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.70 | 49.0 | 4.90e-01 | 72.8% | 97.2% |
| 3qo8A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.70 | 49.0 | 4.90e-01 | 72.8% | 98.1% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.69 | 45.0 | 5.33e-01 | 70.9% | 100.0% |
| 4wpeA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.69 | 56.0 | 4.03e-01 | 86.4% | 75.6% |
| 3cazB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.69 | 61.0 | 4.85e-01 | 99.0% | 89.5% |
| 3vkgA12 | 1.10.287.2610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.69 | 47.0 | 3.67e-01 | 70.9% | 34.0% |
| 2q0oC00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.69 | 45.0 | 4.85e-01 | 70.9% | 79.1% |
| 2oduA02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 45.0 | 4.53e-01 | 70.9% | 65.7% |
| 1zbtA01 | 6.10.140.1950 | Special › Helix non-globular › Helix Hairpins › | 0.67 | 48.0 | 5.30e-01 | 81.6% | 92.8% |
| 3fppA03 | 6.10.140.1990 | Special › Helix non-globular › Helix Hairpins › | 0.67 | 46.0 | 4.97e-01 | 70.9% | 100.0% |
| 2ficB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.67 | 60.0 | 4.82e-01 | 100.0% | 90.0% |
| 3pwxA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.67 | 58.0 | 4.80e-01 | 100.0% | 53.8% |
| 2d1lA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.66 | 53.0 | 4.05e-01 | 87.4% | 78.7% |
| 2ap3A00 | 1.20.120.570 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YkyA-like | 0.66 | 53.0 | 4.35e-01 | 87.4% | 78.6% |
| 2efkA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.66 | 59.0 | 4.41e-01 | 100.0% | 88.9% |
| 3uarA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.66 | 43.0 | 4.33e-01 | 70.9% | 64.5% |
| 1u7lA02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.64 | 52.0 | 4.22e-01 | 85.4% | 83.6% |
| 1urfA00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.64 | 45.0 | 4.98e-01 | 73.8% | 92.6% |
| 6gy8A01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.62 | 55.0 | 3.85e-01 | 99.0% | 61.4% |
| 1kxpD02 | 1.10.246.10 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.59 | 47.0 | 5.04e-01 | 96.1% | 100.0% |
| 4dxwA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.59 | 41.0 | 4.05e-01 | 72.8% | 95.5% |
| 1w9rA00 | 1.20.58.440 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › choline binding protein A | 0.59 | 47.0 | 4.51e-01 | 87.4% | 83.2% |
| 1j5wA02 | 1.20.58.180 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 | 0.58 | 42.0 | 4.87e-01 | 100.0% | 100.0% |
| 3a06B03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.58 | 33.0 | 3.49e-01 | 76.7% | 62.5% |
| 2hydA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.56 | 49.0 | 3.48e-01 | 97.1% | 53.3% |
| 1io1A01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.55 | 49.0 | 4.18e-01 | 100.0% | 79.3% |
| 4u7iA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.51 | 43.0 | 4.52e-01 | 100.0% | 98.9% |
ECOD (52)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5018554 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.77 | 63.0 | 6.47e-01 | 87.4% | 100.0% |
| 4988447 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.76 | 70.0 | 6.76e-01 | 100.0% | 99.1% |
| 3339561 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.75 | 49.0 | 5.06e-01 | 70.9% | 69.0% |
| 3213527 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.73 | 67.0 | 4.81e-01 | 100.0% | 82.8% |
| 5005097 | 3710.1.1.0 ↗ | alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain | 0.72 | 53.0 | 4.85e-01 | 76.7% | 97.7% |
| 3880637 | 3755.3.1.465 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A | 0.72 | 48.0 | 4.27e-01 | 70.9% | 50.0% |
| 3579647 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.71 | 53.0 | 4.66e-01 | 77.7% | 100.0% |
| 3315764 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.71 | 64.0 | 4.50e-01 | 100.0% | 55.0% |
| 3576467 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.71 | 64.0 | 4.56e-01 | 100.0% | 78.0% |
| 3486831 | 220.1.1.22 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › FERM_C | 0.71 | 48.0 | 3.59e-01 | 70.9% | 29.4% |
| 4324117 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.71 | 49.0 | 3.28e-01 | 70.9% | 21.4% |
| 5006401 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.71 | 49.0 | 4.31e-01 | 70.9% | 89.0% |
| 3919688 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.70 | 64.0 | 4.85e-01 | 100.0% | 76.7% |
| 4022306 | 3939.1.1.0 ↗ | alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain | 0.70 | 49.0 | 4.25e-01 | 70.9% | 72.0% |
| 4017411 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.70 | 61.0 | 5.41e-01 | 96.1% | 76.0% |
| 3236352 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.70 | 63.0 | 5.14e-01 | 98.1% | 96.2% |
| 3620978 | 2003.1.2.18 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain | 0.70 | 48.0 | 3.29e-01 | 70.9% | 22.5% |
| 3867942 | 3755.3.1.303 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A_4th | 0.70 | 48.0 | 3.62e-01 | 70.9% | 39.1% |
| 3213281 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.69 | 62.0 | 4.59e-01 | 100.0% | 85.9% |
| 3739176 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.69 | 47.0 | 3.01e-01 | 70.9% | 15.4% |
| 3229891 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.69 | 53.0 | 4.86e-01 | 82.5% | 83.0% |
| 3386973 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.68 | 47.0 | 5.04e-01 | 70.9% | 94.4% |
| 3595868 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.68 | 47.0 | 3.37e-01 | 70.9% | 45.6% |
| 3794996 | 192.12.1.0 ↗ | alpha bundles › Long alpha-hairpin › Transcriptional repressor TraM › Transcriptional repressor TraM | 0.68 | 49.0 | 4.31e-01 | 74.8% | 100.0% |
| 3963427 | 5086.1.1.93 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_EMRA | 0.68 | 47.0 | 4.18e-01 | 70.9% | 64.8% |
| 3289119 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.68 | 45.0 | 3.01e-01 | 70.9% | 18.2% |
| 4036645 | 5086.1.1.92 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE | 0.68 | 46.0 | 3.65e-01 | 70.9% | 36.4% |
| 5026394 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.67 | 61.0 | 5.93e-01 | 100.0% | 95.7% |
| 4006721 | 325.1.7.50 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › PF25876 | 0.67 | 45.0 | 4.91e-01 | 70.9% | 83.5% |
| 3789363 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.67 | 48.0 | 3.14e-01 | 75.7% | 66.1% |
| 4966374 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.66 | 46.0 | 3.80e-01 | 70.9% | 42.9% |
| 3178828 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.66 | 46.0 | 3.21e-01 | 71.8% | 22.8% |
| 3488978 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.66 | 59.0 | 4.28e-01 | 100.0% | 80.3% |
| 3235839 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.66 | 45.0 | 3.78e-01 | 70.9% | 74.3% |
| 3538954 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.66 | 45.0 | 3.26e-01 | 70.9% | 91.4% |
| 3189247 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.65 | 58.0 | 4.49e-01 | 100.0% | 90.6% |
| 3205388 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.65 | 45.0 | 3.41e-01 | 70.9% | 31.1% |
| 4059733 | 4177.1.1.66 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › ATG17_like | 0.64 | 54.0 | 4.30e-01 | 95.1% | 88.6% |
| 3715891 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.64 | 44.0 | 3.77e-01 | 70.9% | 97.0% |
| 4286404 | 3755.1.1.14 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › T3SSipB | 0.64 | 50.0 | 4.10e-01 | 82.5% | 82.2% |
| 3920037 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.63 | 57.0 | 3.82e-01 | 100.0% | 51.7% |
| 4987684 | 3755.1.1.0 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related | 0.63 | 43.0 | 4.05e-01 | 70.9% | 93.8% |
| 3988973 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.62 | 50.0 | 4.76e-01 | 87.4% | 80.0% |
| 3923557 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.62 | 43.0 | 3.40e-01 | 70.9% | 36.5% |
| 5037413 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.61 | 54.0 | 4.60e-01 | 96.1% | 76.4% |
| 3964578 | 5094.1.1.1 ↗ | a+b duplicates or obligate multimers › OmpH-like › OmpH-like › OmpH-like › OmpH | 0.61 | 46.0 | 4.12e-01 | 78.6% | 67.1% |
| 3795763 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.58 | 50.0 | 3.18e-01 | 92.2% | 63.9% |
| 4961507 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.55 | 50.0 | 3.36e-01 | 100.0% | 65.2% |
| 4001189 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.53 | 48.0 | 3.10e-01 | 99.0% | 53.8% |
| 4305317 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.52 | 49.0 | 2.87e-01 | 100.0% | 52.7% |
| 3869913 | 2004.1.1.442 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21 | 0.51 | 46.0 | 3.03e-01 | 100.0% | 32.2% |
| 4015065 | 1075.4.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold | 0.50 | 45.0 | 3.18e-01 | 100.0% | 87.8% |
D3
medium
residues 212-266
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04549.20 best | CD47 | 47.3 | 3.70e-12 | 100.0% | 35.4% |
CATH (46)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4ioeA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.89 | 77.0 | 6.52e-01 | 94.5% | 73.6% |
| 2v6yA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.84 | 64.0 | 5.75e-01 | 81.8% | 64.0% |
| 2yqyA00 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.84 | 76.0 | 5.72e-01 | 100.0% | 80.2% |
| 3fxdB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.83 | 67.0 | 6.61e-01 | 89.1% | 87.9% |
| 2x0cA01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.82 | 71.0 | 4.91e-01 | 96.4% | 75.8% |
| 1lrzA03 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.79 | 65.0 | 6.25e-01 | 90.9% | 80.6% |
| 1d2mA03 | 6.10.140.240 | Special › Helix non-globular › Helix Hairpins › | 0.79 | 63.0 | 5.94e-01 | 87.3% | 72.7% |
| 1b3qA01 | 1.10.287.560 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Histidine kinase CheA-like, homodimeric domain | 0.79 | 66.0 | 6.39e-01 | 92.7% | 87.1% |
| 3gnlB02 | 1.10.287.1890 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.79 | 65.0 | 6.05e-01 | 94.5% | 73.5% |
| 1zpyA00 | 6.10.140.1960 | Special › Helix non-globular › Helix Hairpins › | 0.78 | 65.0 | 5.57e-01 | 94.5% | 62.6% |
| 3pe0A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.78 | 64.0 | 5.28e-01 | 92.7% | 53.5% |
| 2hh7A00 | 1.20.58.1000 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer | 0.78 | 64.0 | 5.63e-01 | 100.0% | 61.2% |
| 3lbxB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.78 | 66.0 | 5.30e-01 | 94.5% | 55.1% |
| 2q1kA00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.78 | 60.0 | 6.13e-01 | 92.7% | 90.4% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.78 | 65.0 | 6.20e-01 | 96.4% | 88.1% |
| 3fb2A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.78 | 65.0 | 5.33e-01 | 96.4% | 52.4% |
| 1j30A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.77 | 64.0 | 4.83e-01 | 96.4% | 41.8% |
| 6ynwH01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.77 | 65.0 | 5.92e-01 | 96.4% | 95.9% |
| 2rpaA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.76 | 60.0 | 5.39e-01 | 87.3% | 63.6% |
| 2ewfA02 | 1.20.1270.310 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.76 | 60.0 | 5.24e-01 | 85.5% | 58.0% |
| 3l9fA02 | 6.10.140.1570 | Special › Helix non-globular › Helix Hairpins › | 0.75 | 61.0 | 5.48e-01 | 94.5% | 70.4% |
| 1s35A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.75 | 61.0 | 4.97e-01 | 94.5% | 50.9% |
| 4l8jA04 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.74 | 63.0 | 6.16e-01 | 94.5% | 93.2% |
| 4dciA00 | 6.10.140.1110 | Special › Helix non-globular › Helix Hairpins › | 0.74 | 63.0 | 4.64e-01 | 96.4% | 36.7% |
| 2xubA05 | 6.10.140.1450 | Special › Helix non-globular › Helix Hairpins › | 0.74 | 59.0 | 5.03e-01 | 92.7% | 89.6% |
| 1vf7A03 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.74 | 62.0 | 6.05e-01 | 94.5% | 90.0% |
| 2rp4A00 | 6.10.280.60 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain | 0.74 | 55.0 | 5.15e-01 | 87.3% | 64.8% |
| 1ni3A03 | 1.10.150.300 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Obg-related GTPase Ych/YyaF, coiled-coil domain | 0.73 | 61.0 | 5.27e-01 | 96.4% | 73.6% |
| 4gzrB00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.73 | 60.0 | 5.47e-01 | 94.5% | 71.4% |
| 4id0A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.72 | 64.0 | 5.07e-01 | 100.0% | 52.7% |
| 4e6nA02 | 6.10.140.1010 | Special › Helix non-globular › Helix Hairpins › | 0.72 | 61.0 | 5.78e-01 | 98.2% | 97.0% |
| 7ymiZ01 | 1.10.287.740 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre | 0.71 | 57.0 | 5.66e-01 | 92.7% | 96.6% |
| 3lssA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.71 | 59.0 | 4.81e-01 | 98.2% | 82.1% |
| 2wzkA01 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.70 | 58.0 | 4.50e-01 | 94.5% | 57.5% |
| 6z01B03 | 1.10.132.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.70 | 55.0 | 4.06e-01 | 89.1% | 34.4% |
| 5b1aC01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.69 | 56.0 | 5.32e-01 | 98.2% | 76.5% |
| 2jdiG01 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.69 | 51.0 | 4.97e-01 | 81.8% | 73.8% |
| 2btqB03 | 1.10.287.600 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.67 | 47.0 | 4.78e-01 | 74.5% | 100.0% |
| 4h63K00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.66 | 53.0 | 4.55e-01 | 96.4% | 55.1% |
| 8igrI01 | 2.40.270.10 | Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 | 0.66 | 52.0 | 3.71e-01 | 89.1% | 77.3% |
| 2lw1A00 | 1.10.287.380 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain | 0.66 | 55.0 | 4.85e-01 | 96.4% | 74.1% |
| 5mmjb02 | 1.10.287.610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.65 | 47.0 | 4.83e-01 | 76.4% | 90.4% |
| 2rkhA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.64 | 51.0 | 4.73e-01 | 94.5% | 71.1% |
| 4fvmA06 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.63 | 47.0 | 4.83e-01 | 90.9% | 100.0% |
| 1n1cA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.63 | 47.0 | 4.30e-01 | 87.3% | 58.5% |
| 4hb1A00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.62 | 44.0 | 4.66e-01 | 81.8% | 100.0% |
ECOD (27)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4028334 | 2004.1.1.505 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11, AAA_30 | 0.93 | 86.0 | 5.18e-01 | 100.0% | 18.7% |
| 3706396 | 630.1.1.0 ↗ | a+b complex topology › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain | 0.90 | 79.0 | 5.43e-01 | 94.5% | 31.8% |
| 5016327 | 605.1.1.2 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › H-kinase_dim | 0.85 | 72.0 | 6.61e-01 | 92.7% | 77.1% |
| 4152566 | 4274.1.1.1 ↗ | extended segments › Transmembrane helices in MalF N-terminal region › Transmembrane helices in MalF N-terminal region › Transmembrane helices in MalF N-terminal region › MalF_N_TM | 0.85 | 69.0 | 6.95e-01 | 89.1% | 89.1% |
| 3249654 | 604.5.1.32 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › TMEM120A-B | 0.83 | 71.0 | 6.23e-01 | 94.5% | 67.5% |
| 4329615 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.82 | 70.0 | 6.47e-01 | 94.5% | 77.1% |
| 3253483 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.82 | 69.0 | 6.42e-01 | 94.5% | 82.9% |
| 4115372 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.81 | 72.0 | 5.70e-01 | 100.0% | 76.4% |
| 3174647 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.80 | 68.0 | 6.28e-01 | 94.5% | 82.9% |
| 4667192 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.79 | 69.0 | 5.81e-01 | 100.0% | 75.8% |
| 3290879 | 3922.1.1.155 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DUF4349 | 0.79 | 66.0 | 6.15e-01 | 94.5% | 80.0% |
| 4674 | 192.7.1.1 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › FemAB | 0.79 | 65.0 | 6.20e-01 | 92.7% | 80.0% |
| 4446039 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.79 | 66.0 | 6.12e-01 | 94.5% | 78.6% |
| 3201381 | 192.8.1.139 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › Fung_rhodopsin | 0.78 | 64.0 | 5.83e-01 | 94.5% | 68.0% |
| 3225484 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.78 | 62.0 | 5.77e-01 | 87.3% | 71.4% |
| 3977054 | 4274.1.1.1 ↗ | extended segments › Transmembrane helices in MalF N-terminal region › Transmembrane helices in MalF N-terminal region › Transmembrane helices in MalF N-terminal region › MalF_N_TM | 0.77 | 63.0 | 6.31e-01 | 92.7% | 98.2% |
| 3480097 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.77 | 60.0 | 5.60e-01 | 87.3% | 71.4% |
| 3377936 | 3922.1.1.173 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DUF3493 | 0.76 | 64.0 | 5.57e-01 | 94.5% | 65.9% |
| 3588172 | 10.12.1.0 ↗ | beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix | 0.76 | 65.0 | 4.79e-01 | 100.0% | 63.3% |
| 1566346 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.75 | 63.0 | 5.86e-01 | 98.2% | 78.9% |
| 3191420 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.75 | 61.0 | 5.89e-01 | 94.5% | 83.1% |
| 3980428 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.75 | 63.0 | 5.72e-01 | 96.4% | 74.7% |
| 3717860 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.75 | 63.0 | 5.42e-01 | 96.4% | 64.4% |
| 3520738 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.73 | 60.0 | 4.43e-01 | 94.5% | 36.1% |
| 5031927 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.72 | 60.0 | 5.34e-01 | 100.0% | 77.6% |
| 3657123 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.71 | 56.0 | 4.84e-01 | 94.5% | 87.4% |
| 3468069 | 6055.1.1.0 ↗ | extended segments › Preprotein translocase subunit YajC › Preprotein translocase subunit YajC › Preprotein translocase subunit YajC | 0.59 | 45.0 | 4.68e-01 | 92.7% | 100.0% |