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CP025712.1AUO37541.1YDC107_5424__00064

Bact-Vir

CP025712.1__AUO37541.1__YDC107_5424__00064

Identity

Accession:: CP025712 ↗
Kingdom:: phage

Quality

88.1 mean pLDDT

Taxonomy

Heunggongvirae› Uroviricota› Caudoviricetes› Ravinvirus› Escherichia_phage_YDC107_1

TaxID: 2056767

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 239-398

PDB

Domain cluster: rep: MK064563__AZI75768.1__SBFV2-gp01__00001__D223-383

CATH (78)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
7clgB02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.77	60.0	6.10e-01	100.0%	82.5%
3rc3A03	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.77	63.0	6.33e-01	100.0%	85.5%
2pl3A00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.76	71.0	6.15e-01	100.0%	67.2%
3berA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.76	70.0	6.19e-01	100.0%	70.5%
3i5xA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.75	71.0	6.02e-01	100.0%	70.0%
3sxuA00	3.40.50.10110	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › DNA polymerase III subunit chi	0.75	57.0	6.01e-01	99.4%	86.3%
6vsxA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.74	57.0	5.77e-01	99.4%	80.5%
4a15A01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.74	66.0	6.25e-01	100.0%	81.5%
8ebtA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.73	64.0	6.14e-01	100.0%	81.6%
5supC01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.73	69.0	6.20e-01	100.0%	74.6%
1a1vA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.73	52.0	5.67e-01	80.6%	86.7%
2kbeA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.71	65.0	5.73e-01	100.0%	68.6%
8alzB05	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.71	66.0	6.04e-01	100.0%	77.6%
6eudA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.71	60.0	5.94e-01	100.0%	84.8%
1gkuB03	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.71	58.0	5.55e-01	99.4%	76.1%
3ic5A00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.70	40.0	4.63e-01	100.0%	77.4%
8oosG01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.70	66.0	5.94e-01	99.4%	82.8%
3mwyW03	3.40.50.10810	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Tandem AAA-ATPase domain	0.69	65.0	5.38e-01	100.0%	66.0%
3crvA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.69	65.0	5.52e-01	100.0%	82.9%
7r7jA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.69	61.0	5.78e-01	100.0%	80.6%
1z6aA01	3.40.50.10810	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Tandem AAA-ATPase domain	0.69	64.0	5.87e-01	100.0%	85.0%
1wp9A02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.67	55.0	5.71e-01	86.9%	92.6%
6qelJ01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.67	47.0	4.51e-01	100.0%	64.0%
8dgfB01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.67	47.0	4.42e-01	100.0%	60.2%
1tzbA02	3.40.50.10490	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1	0.66	40.0	4.22e-01	80.6%	66.9%
1gpjA02	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.66	46.0	4.70e-01	100.0%	74.0%
2ocaA03	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.65	61.0	5.52e-01	100.0%	82.2%
1yksA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.64	56.0	5.39e-01	92.5%	81.7%
3i0zA02	3.40.50.10490	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1	0.64	47.0	4.56e-01	100.0%	68.2%
3do8A00	3.40.50.620	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs	0.63	43.0	4.63e-01	100.0%	81.5%
3gk5A00	3.40.250.10	Alpha Beta › 3-Layer(aba) Sandwich › Oxidized Rhodanese; domain 1 › Rhodanese-like domain	0.63	34.0	4.13e-01	79.4%	82.0%
3pg5A00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.62	53.0	4.30e-01	91.3%	91.9%
4pyrA02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.62	45.0	5.05e-01	100.0%	99.2%
1pjrA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.62	58.0	5.32e-01	100.0%	83.2%
3qoyA02	3.40.50.790	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Ribosomal protein L1/L10, domain II	0.62	33.0	4.11e-01	74.4%	86.0%
2vl7A03	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.62	56.0	5.42e-01	100.0%	87.6%
3bosB01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.60	46.0	4.67e-01	80.6%	84.0%
1ozhA02	3.40.50.1220	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain	0.60	47.0	4.78e-01	100.0%	85.1%
1iz0A02	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.60	45.0	4.60e-01	100.0%	81.2%
2h6eA02	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.60	48.0	5.05e-01	100.0%	95.8%
8jx6B01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.59	53.0	4.90e-01	100.0%	76.0%
3e48A01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.59	47.0	4.49e-01	99.4%	73.2%
3menB00	3.40.800.20	Alpha Beta › 3-Layer(aba) Sandwich › Arginase; Chain A › Histone deacetylase domain	0.59	51.0	4.03e-01	95.0%	50.6%
3hl0A01	3.40.50.1970	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.59	46.0	4.71e-01	100.0%	84.3%
4dzzA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.59	50.0	4.60e-01	91.9%	79.6%
4mptA02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.58	49.0	5.10e-01	100.0%	98.0%
3lfjB00	3.40.35.10	Alpha Beta › 3-Layer(aba) Sandwich › Fructose Permease › Phosphotransferase system, sorbose subfamily IIB component	0.58	44.0	4.36e-01	78.8%	95.8%
3mbhA00	3.40.1190.20	Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase	0.58	49.0	4.06e-01	92.5%	71.3%
3fwzA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.57	42.0	4.45e-01	91.9%	86.4%
4ms4A02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.57	50.0	4.73e-01	95.6%	94.2%
5wq5A01	3.40.50.1970	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.57	46.0	4.65e-01	100.0%	86.2%
3ez2A02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.57	49.0	4.00e-01	92.5%	80.1%
3kb2A00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.57	42.0	4.16e-01	76.9%	87.7%
4gvlA01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.56	40.0	4.29e-01	91.3%	85.3%
1gvnD00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.56	43.0	3.67e-01	80.6%	72.2%
1q6zA02	3.40.50.1220	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain	0.56	44.0	4.41e-01	100.0%	81.5%
1qhxA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.56	40.0	3.93e-01	73.8%	91.0%
3oziB00	3.40.50.10140	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Toll/interleukin-1 receptor homology (TIR) domain	0.56	47.0	4.64e-01	91.3%	85.1%
5okaA00	3.20.20.80	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases	0.56	50.0	3.66e-01	100.0%	75.8%
3f2vA00	3.40.50.360	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain	0.55	47.0	4.60e-01	91.3%	85.1%
1ovmA02	3.40.50.1220	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain	0.55	43.0	4.39e-01	100.0%	84.0%
3e8sA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.55	51.0	4.54e-01	100.0%	75.9%
3uwpA02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.55	49.0	4.41e-01	100.0%	70.9%
2amjB00	3.40.50.360	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain	0.55	47.0	4.48e-01	91.9%	84.2%
3kfvA02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.54	38.0	4.05e-01	72.5%	87.2%
3looB01	3.40.1190.20	Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase	0.54	49.0	4.09e-01	100.0%	66.2%
1wcv100	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.54	48.0	4.25e-01	100.0%	65.8%
3i8oA01	3.40.50.1010	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease	0.54	38.0	4.16e-01	99.4%	89.8%
2bkaA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.54	47.0	4.22e-01	97.5%	95.2%
1in4A01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.53	41.0	4.24e-01	80.6%	87.2%
3wj7A00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.53	45.0	3.60e-01	91.9%	69.4%
3fkqA02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.53	47.0	4.20e-01	100.0%	81.4%
1o4wA00	3.40.50.1010	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease	0.52	34.0	3.76e-01	100.0%	83.2%
1vcvA00	3.20.20.70	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I	0.52	46.0	4.18e-01	100.0%	95.6%
3qvoA00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.51	43.0	4.05e-01	92.5%	93.4%
3zyzA02	3.40.50.1700	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycoside hydrolase family 3 C-terminal domain	0.50	46.0	3.88e-01	100.0%	94.0%
1zd1B00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.50	42.0	3.69e-01	91.3%	87.8%
6mfvC01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.50	37.0	3.90e-01	78.1%	98.6%

ECOD (88)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3245343	2004.1.1.29 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD	0.80	70.0	6.16e-01	100.0%	66.4%
3947000	2004.1.1.120 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ResIII	0.79	63.0	6.50e-01	100.0%	87.3%
4953117	2004.1.1.120 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ResIII	0.78	63.0	6.14e-01	100.0%	77.1%
4030842	2004.1.1.29 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD	0.76	69.0	6.49e-01	100.0%	80.5%
4997487	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.76	68.0	5.86e-01	100.0%	63.8%
4948563	2004.1.1.29 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD	0.75	65.0	5.94e-01	100.0%	70.7%
4175288	2004.1.1.364 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD+Helicase_C	0.75	71.0	4.72e-01	100.0%	31.2%
3935945	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.74	57.0	5.94e-01	87.5%	85.3%
3231316	2004.1.1.29 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD	0.74	70.0	5.52e-01	100.0%	53.1%
3229137	2004.1.1.23 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom	0.73	61.0	5.93e-01	91.3%	79.4%
4947505	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.73	69.0	5.63e-01	100.0%	66.5%
4030343	2004.1.1.23 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom	0.73	69.0	5.07e-01	100.0%	49.9%
3934285	2004.1.1.29 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD	0.73	69.0	5.96e-01	100.0%	69.8%
4928308	2004.1.1.220 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SWI2_SNF2	0.73	61.0	4.37e-01	100.0%	32.0%
4967737	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.72	66.0	4.84e-01	100.0%	39.2%
5000494	2004.1.1.29 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD	0.72	68.0	5.96e-01	100.0%	73.0%
4950211	2004.1.1.120 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ResIII	0.72	63.0	5.78e-01	100.0%	73.5%
4023184	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.71	67.0	4.50e-01	100.0%	35.9%
3614043	2004.1.1.23 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom	0.71	67.0	5.29e-01	100.0%	61.6%
5029435	2004.1.1.220 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SWI2_SNF2	0.71	63.0	5.86e-01	100.0%	76.4%
3169310	2004.1.1.428 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom, Helicase_C, HDA2-3	0.71	67.0	4.40e-01	100.0%	29.7%
5039478	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.71	61.0	4.56e-01	100.0%	38.9%
3681549	2004.1.1.23 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom	0.71	67.0	5.46e-01	100.0%	71.6%
3219689	2004.1.1.23 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom	0.71	66.0	5.75e-01	100.0%	78.3%
None	—		0.71	67.0	5.32e-01	100.0%	67.5%
4955500	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.70	66.0	4.22e-01	100.0%	23.8%
3968942	2004.1.1.23 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom	0.70	67.0	5.26e-01	100.0%	59.3%
3593302	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.70	66.0	5.09e-01	100.0%	61.8%
5001121	2004.1.1.144 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD_2	0.70	66.0	5.59e-01	100.0%	82.8%
3793853	2004.1.1.24 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom,Helicase_C	0.70	66.0	4.41e-01	100.0%	33.8%
3252815	2004.1.1.23 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom	0.70	66.0	5.41e-01	100.0%	65.8%
3620821	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.70	66.0	3.73e-01	100.0%	12.0%
4027472	2004.1.1.23 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom	0.70	66.0	5.40e-01	100.0%	66.9%
3229856	2004.1.1.23 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom	0.70	66.0	5.35e-01	100.0%	66.1%
3508222	2004.1.1.29 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD	0.70	61.0	5.41e-01	100.0%	66.2%
3936409	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.70	62.0	5.39e-01	100.0%	63.7%
4936052	2004.1.1.23 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom	0.69	65.0	5.71e-01	100.0%	76.5%
3929438	2004.1.1.23 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom	0.69	66.0	5.37e-01	100.0%	68.0%
5071742	2004.1.1.120 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ResIII	0.69	65.0	5.66e-01	100.0%	76.2%
5072107	2004.1.1.120 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ResIII	0.69	65.0	5.70e-01	100.0%	76.5%
3795974	2004.1.1.24 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom,Helicase_C	0.69	65.0	4.42e-01	100.0%	37.5%
3263816	2004.1.1.120 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ResIII	0.69	64.0	5.31e-01	100.0%	59.2%
4934401	2004.1.1.29 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD	0.69	65.0	5.47e-01	100.0%	67.8%
5035743	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.69	65.0	4.29e-01	100.0%	29.3%
3629834	2004.1.1.629 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom, Helicase_C, ResIII	0.69	65.0	4.49e-01	100.0%	40.6%
4965517	2004.1.1.144 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD_2	0.69	64.0	5.58e-01	100.0%	80.0%
3961512	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.67	63.0	5.26e-01	100.0%	63.0%
1870822	2007.1.2.13 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_6	0.67	49.0	5.48e-01	100.0%	97.6%
3262130	2004.1.1.238 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C,ResIII	0.67	63.0	4.55e-01	100.0%	38.8%
5045020	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.67	62.0	5.07e-01	100.0%	64.2%
3955660	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.67	62.0	5.19e-01	100.0%	63.0%
3989169	2003.1.1.28 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › TrkA_N	0.66	45.0	4.79e-01	100.0%	80.0%
3275509	2004.1.1.220 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SWI2_SNF2	0.65	62.0	5.26e-01	100.0%	65.7%
4460358	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.65	60.0	4.86e-01	99.4%	86.1%
3971716	2004.1.1.220 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SWI2_SNF2	0.65	60.0	5.09e-01	100.0%	74.2%
3575535	1.1.7.113 ↗	beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › AAA_11, AAA_12	0.64	61.0	4.24e-01	100.0%	43.7%
3629939	2004.1.1.473 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ResIII, AAA_11	0.64	61.0	4.77e-01	100.0%	65.5%
3801347	2004.1.1.184 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11	0.64	60.0	4.76e-01	100.0%	68.0%
3716079	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.63	58.0	4.25e-01	100.0%	38.2%
3713295	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.63	57.0	5.07e-01	96.9%	84.1%
5018200	2004.1.1.220 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SWI2_SNF2	0.63	59.0	4.05e-01	100.0%	35.9%
5031824	2004.1.1.220 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SWI2_SNF2	0.63	58.0	4.02e-01	100.0%	32.0%
5010340	2003.1.4.1 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › TPP_enzyme_M	0.62	48.0	4.63e-01	100.0%	71.4%
368898	2003.1.1.39 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Sacchrp_dh_NADP	0.61	39.0	4.41e-01	85.0%	87.0%
3279235	2003.1.4.1 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › TPP_enzyme_M	0.61	47.0	4.61e-01	100.0%	74.3%
None	—		0.61	47.0	4.58e-01	100.0%	72.8%
4968460	2004.1.1.188 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Cytidylate_kin2	0.60	43.0	4.33e-01	74.4%	86.1%
3597434	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.59	45.0	4.32e-01	80.6%	87.4%
3743971	2004.1.1.184 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11	0.59	45.0	3.30e-01	80.0%	70.0%
4125296	2003.1.4.1 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › TPP_enzyme_M	0.59	46.0	4.38e-01	100.0%	68.9%
4167912	102.1.1.6 ↗	alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › Methyltransf_5	0.59	54.0	4.95e-01	100.0%	93.3%
3974418	2003.1.4.1 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › TPP_enzyme_M	0.59	47.0	4.58e-01	100.0%	77.1%
4318504	2004.1.1.156 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_5	0.58	45.0	4.43e-01	80.6%	94.7%
3278320	2003.1.1.5 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › ADH_zinc_N	0.58	46.0	4.54e-01	100.0%	79.4%
3734230	2003.1.4.1 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › TPP_enzyme_M	0.57	44.0	4.32e-01	100.0%	73.7%
3945647	2002.1.1.12 ↗	a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_1	0.56	49.0	3.63e-01	98.1%	81.4%
3483060	2004.1.1.366 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NPHP3_N	0.54	42.0	4.08e-01	81.9%	78.9%
4995940	2003.1.1.28 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › TrkA_N	0.54	40.0	4.17e-01	91.9%	82.7%
3680789	2004.1.1.505 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11, AAA_30	0.54	49.0	3.67e-01	100.0%	65.9%
None	—		0.53	46.0	3.32e-01	95.6%	61.3%
3249477	2005.1.1.0 ↗	a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains	0.53	36.0	4.03e-01	100.0%	90.4%
4185100	2002.1.1.121 ↗	a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM,Mob_synth_C	0.52	45.0	3.62e-01	95.6%	72.1%
3586943	2004.1.1.68 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › IstB_IS21	0.52	47.0	4.33e-01	100.0%	77.6%
4969416	2002.1.1.84 ↗	a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › MtrH	0.52	46.0	4.18e-01	96.9%	98.1%
5011835	2002.1.1.446 ↗	a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › DUF3463	0.52	44.0	3.59e-01	95.0%	65.5%
5035600	2008.1.1.7 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › ERCC4	0.51	37.0	3.75e-01	75.0%	76.2%
3356077	109.4.1.1616 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_Trm732_C	0.50	43.0	3.60e-01	93.1%	75.4%
5026080	2002.1.1.120 ↗	a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM	0.50	44.0	3.69e-01	98.1%	71.0%

D2 high residues 413-546_602-643

PDB

Domain cluster: representative

CATH (87)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
7pliF02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.78	64.0	6.86e-01	92.0%	99.3%
2p6nA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.77	63.0	6.63e-01	92.6%	94.4%
1oywA02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.76	54.0	6.13e-01	73.9%	96.2%
2hyiC02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.75	64.0	6.59e-01	95.5%	94.0%
1hv8A02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.75	61.0	6.57e-01	92.0%	99.3%
6b4kB02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.74	63.0	6.45e-01	94.3%	92.4%
6x50A03	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.74	61.0	5.77e-01	91.5%	72.4%
4w7sA02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.74	64.0	6.29e-01	93.2%	86.0%
6yhrA02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.74	65.0	6.11e-01	92.6%	97.6%
1gkuB03	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.74	59.0	5.86e-01	93.2%	80.6%
2yjtD00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.74	64.0	6.51e-01	96.6%	94.1%
3i5xA02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.74	68.0	5.91e-01	100.0%	66.9%
1c4oA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.73	51.0	5.47e-01	93.8%	81.7%
7a8rA02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.73	64.0	6.12e-01	92.6%	97.5%
1c4oA03	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.72	60.0	6.06e-01	89.8%	87.4%
6fwrA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.71	61.0	5.86e-01	90.9%	97.5%
6jimB01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.71	53.0	5.83e-01	95.5%	95.1%
6bogA05	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.71	60.0	5.64e-01	89.2%	96.7%
1rifA02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.70	59.0	5.71e-01	93.2%	80.2%
2ocaA03	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.70	63.0	5.99e-01	96.6%	99.0%
1a1vA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.70	50.0	5.59e-01	75.0%	94.1%
6jytA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.70	58.0	5.95e-01	90.9%	91.0%
8oosG01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.69	61.0	5.73e-01	93.2%	88.0%
4q48A01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.69	62.0	5.92e-01	96.0%	84.0%
2eyqA04	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.69	56.0	5.00e-01	90.3%	61.0%
7nadx02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.69	64.0	5.75e-01	100.0%	92.8%
1wp9A02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.69	55.0	5.92e-01	85.2%	98.0%
1z5zB01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.69	53.0	5.67e-01	88.1%	91.6%
1gm5A04	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.68	58.0	5.56e-01	98.3%	78.9%
3mwyW04	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.68	62.0	5.32e-01	96.6%	92.9%
2xgjB01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.68	57.0	5.43e-01	96.6%	76.7%
3v4rA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.66	60.0	5.34e-01	96.6%	87.8%
3mwyW03	3.40.50.10810	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Tandem AAA-ATPase domain	0.66	60.0	5.23e-01	98.9%	73.9%
2vl7A01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.65	54.0	5.53e-01	96.0%	89.5%
1m6nA03	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.65	58.0	5.86e-01	96.0%	96.0%
4idhA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.62	56.0	5.29e-01	98.9%	81.2%
6z6fA01	3.40.800.20	Alpha Beta › 3-Layer(aba) Sandwich › Arginase; Chain A › Histone deacetylase domain	0.62	52.0	4.08e-01	89.2%	55.4%
1tzbA02	3.40.50.10490	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1	0.62	40.0	4.44e-01	97.2%	81.3%
3axsA01	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.61	54.0	4.47e-01	97.2%	83.9%
2c9oA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.61	44.0	4.21e-01	73.3%	82.5%
4rhiA00	3.40.800.10	Alpha Beta › 3-Layer(aba) Sandwich › Arginase; Chain A › Ureohydrolase domain	0.61	52.0	4.26e-01	90.9%	87.7%
2hf9B00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.60	49.0	4.69e-01	86.9%	85.6%
4qdiA02	3.40.1190.10	Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain	0.60	50.0	4.57e-01	88.6%	80.8%
3eyeA00	3.40.35.10	Alpha Beta › 3-Layer(aba) Sandwich › Fructose Permease › Phosphotransferase system, sorbose subfamily IIB component	0.60	46.0	4.91e-01	93.8%	93.5%
2ejbA00	3.40.50.1950	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavin prenyltransferase-like	0.59	48.0	4.86e-01	94.9%	85.8%
2ekdA00	3.40.50.11570	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Protein of unknown function DUF257	0.59	52.0	5.04e-01	96.0%	84.7%
3zl8A02	3.40.1190.10	Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain	0.59	49.0	4.55e-01	88.6%	91.6%
2l82A00	3.40.50.11230	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.59	45.0	4.65e-01	95.5%	85.2%
3tw8A02	3.40.50.11500	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › DENN domain, C-terminal lobe	0.59	44.0	4.55e-01	97.2%	81.7%
3vkgA05	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.59	42.0	4.51e-01	73.3%	99.3%
8jx6B01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.59	53.0	5.06e-01	98.9%	85.5%
4hi0E00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.58	47.0	4.61e-01	86.9%	94.4%
5fhgA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.58	50.0	4.88e-01	97.2%	83.9%
3duwA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.58	50.0	4.70e-01	94.9%	78.1%
1d2gA02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.57	49.0	4.81e-01	92.0%	92.0%
3hl0A01	3.40.50.1970	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.57	45.0	4.71e-01	98.3%	91.8%
1h1lD03	3.40.50.1980	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain	0.56	35.0	3.93e-01	87.5%	80.5%
5wq5A01	3.40.50.1970	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.56	45.0	4.75e-01	98.3%	94.3%
4qysA02	3.40.50.1100	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.56	34.0	4.22e-01	92.6%	100.0%
2b8tA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.56	41.0	4.55e-01	93.2%	97.8%
4toiA01	3.40.50.10490	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1	0.55	38.0	3.87e-01	97.7%	69.7%
3i0zA02	3.40.50.10490	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1	0.55	43.0	4.32e-01	97.2%	81.2%
1dwoA00	3.40.50.1820	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain	0.55	46.0	4.08e-01	90.9%	95.0%
3cgbA02	3.50.50.60	Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain	0.55	36.0	3.93e-01	81.2%	79.2%
3qvmB00	3.40.50.1820	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain	0.55	45.0	3.93e-01	89.8%	87.1%
3vkgA07	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.55	39.0	3.09e-01	74.4%	88.4%
4uhcA00	3.40.50.1820	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain	0.54	45.0	3.93e-01	89.8%	86.0%
1j1iA00	3.40.50.1820	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain	0.54	45.0	4.01e-01	89.8%	89.5%
3qxcA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.54	47.0	4.41e-01	96.0%	92.9%
7otsB01	3.40.50.1820	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain	0.54	45.0	3.91e-01	89.8%	87.2%
5hfjC00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.54	45.0	4.34e-01	90.3%	100.0%
2aznA00	3.40.430.10	Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A	0.54	47.0	4.41e-01	96.0%	93.6%
2ocgA00	3.40.50.1820	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain	0.54	45.0	4.01e-01	90.3%	88.2%
3v48A00	3.40.50.1820	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain	0.54	44.0	3.91e-01	89.8%	89.9%
3c5vA00	3.40.50.1820	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain	0.53	44.0	3.81e-01	90.3%	82.0%
1u2eA00	3.40.50.1820	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain	0.53	44.0	3.82e-01	89.8%	86.7%
2xtmA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.53	44.0	4.20e-01	88.1%	85.0%
1i1nA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.53	42.0	3.89e-01	89.2%	65.2%
4oxiA01	3.40.50.12780	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain	0.53	46.0	3.53e-01	94.9%	44.7%
1sqsA00	3.40.50.360	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain	0.53	44.0	4.02e-01	88.1%	73.2%
3odpA02	3.40.50.10490	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1	0.53	42.0	4.19e-01	97.2%	80.2%
3e0xA00	3.40.50.1820	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain	0.52	44.0	4.03e-01	91.5%	93.5%
2vatL00	3.40.50.1820	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain	0.52	43.0	3.51e-01	88.1%	85.0%
3tejA00	3.40.50.1820	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain	0.52	43.0	3.61e-01	89.8%	68.4%
4wfsA01	3.20.20.70	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I	0.52	45.0	4.23e-01	95.5%	99.5%
5jd6A00	3.40.50.1820	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain	0.51	42.0	3.99e-01	89.8%	88.6%
1rrmA01	3.40.50.1970	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.51	46.0	4.57e-01	98.3%	95.1%

ECOD (95)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3602638	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.77	60.0	4.49e-01	94.9%	35.2%
None	—		0.76	62.0	5.79e-01	89.2%	69.8%
3708070	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.75	69.0	5.75e-01	97.2%	91.6%
4543907	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.75	70.0	6.07e-01	100.0%	74.6%
5078829	2004.1.1.233 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Cas3-like_C_2	0.75	63.0	4.67e-01	89.2%	38.6%
3595401	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.75	63.0	5.43e-01	88.1%	84.6%
3742109	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.74	66.0	5.80e-01	93.8%	78.8%
3983441	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.74	58.0	6.13e-01	80.1%	95.5%
4392500	2004.1.1.233 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Cas3-like_C_2	0.74	63.0	5.89e-01	88.6%	83.8%
5021425	2004.1.1.233 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Cas3-like_C_2	0.74	63.0	4.14e-01	89.2%	26.0%
3995120	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.74	64.0	6.00e-01	97.2%	76.7%
3618647	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.74	62.0	6.31e-01	92.6%	91.2%
3429073	2004.1.1.24 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom,Helicase_C	0.74	64.0	4.56e-01	91.5%	47.2%
5008480	2004.1.1.233 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Cas3-like_C_2	0.73	62.0	6.24e-01	89.2%	92.8%
5060857	2004.1.1.194 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C_2	0.73	65.0	5.98e-01	93.8%	92.7%
5071557	2004.1.1.233 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Cas3-like_C_2	0.73	59.0	5.72e-01	84.1%	83.9%
3876764	2004.1.1.428 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom, Helicase_C, HDA2-3	0.73	66.0	4.34e-01	96.0%	42.8%
3875625	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.73	61.0	3.59e-01	88.1%	20.3%
3738437	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.73	61.0	4.87e-01	88.1%	73.0%
4521587	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.73	61.0	6.14e-01	88.6%	96.1%
5049295	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.73	61.0	5.30e-01	88.1%	88.1%
3724988	2004.1.1.184 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11	0.73	66.0	5.07e-01	96.0%	71.6%
3672903	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.72	66.0	5.41e-01	96.0%	87.3%
5038482	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.72	64.0	5.56e-01	93.8%	78.8%
3271554	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.72	61.0	5.27e-01	88.1%	86.9%
5022287	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.72	58.0	5.76e-01	85.8%	81.1%
5022253	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.72	60.0	5.58e-01	88.1%	71.2%
4015807	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.72	61.0	5.08e-01	88.1%	88.1%
3446823	2004.1.1.24 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom,Helicase_C	0.72	65.0	4.45e-01	96.0%	45.2%
4020971	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.72	67.0	5.97e-01	100.0%	78.8%
4146438	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.72	67.0	5.93e-01	100.0%	88.0%
3601579	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.72	65.0	5.42e-01	96.6%	98.0%
3588100	2004.1.1.194 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C_2	0.72	65.0	5.87e-01	95.5%	88.3%
4948238	2004.1.1.194 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C_2	0.72	65.0	5.90e-01	95.5%	92.0%
3692064	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.72	66.0	5.11e-01	98.3%	95.9%
3690329	2004.1.1.473 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ResIII, AAA_11	0.72	66.0	5.13e-01	98.3%	85.2%
3719162	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.72	67.0	5.77e-01	100.0%	90.9%
3729087	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.72	64.0	4.82e-01	93.8%	93.8%
3214489	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.72	63.0	6.11e-01	93.2%	91.8%
4037650	161.1.1.0 ↗	alpha complex topology › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA	0.72	59.0	3.81e-01	85.8%	25.2%
3640604	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.71	60.0	4.99e-01	88.1%	90.1%
3926091	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.71	67.0	6.44e-01	100.0%	90.3%
4223268	2004.1.1.24 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom,Helicase_C	0.71	60.0	5.02e-01	87.5%	87.0%
5037094	2004.1.1.194 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C_2	0.71	64.0	5.87e-01	95.5%	91.6%
2533813	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.71	59.0	5.53e-01	89.2%	72.2%
4949753	2004.1.1.194 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C_2	0.71	64.0	5.91e-01	95.5%	93.6%
3612447	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.71	66.0	5.07e-01	100.0%	89.1%
5034481	2004.1.1.194 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C_2	0.71	63.0	5.84e-01	93.8%	90.9%
3628105	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.71	60.0	4.82e-01	88.1%	86.9%
4972194	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.71	58.0	5.78e-01	88.1%	83.3%
4324010	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.71	66.0	5.79e-01	100.0%	70.6%
5069051	2004.1.1.194 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C_2	0.71	63.0	5.91e-01	93.8%	95.7%
4943982	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.71	64.0	6.29e-01	98.9%	90.3%
3471510	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.71	66.0	5.76e-01	100.0%	90.2%
4452094	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.71	60.0	6.02e-01	88.6%	96.6%
4943169	2004.1.1.184 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11	0.70	64.0	5.32e-01	96.6%	62.4%
3668729	2004.1.1.23 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom	0.70	64.0	5.34e-01	97.2%	72.2%
2755522	2004.1.1.31 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C,RapA_C	0.70	60.0	5.11e-01	89.2%	75.6%
3665216	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.70	59.0	4.92e-01	88.1%	90.1%
3797023	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.70	65.0	5.76e-01	100.0%	86.0%
3841485	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.70	64.0	5.07e-01	96.6%	91.6%
3934492	2004.1.1.24 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom,Helicase_C	0.70	64.0	4.27e-01	96.0%	46.3%
3882016	2004.1.1.698 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom, Helicase_C, ResIII, HDA2-3	0.70	63.0	4.12e-01	96.0%	46.5%
3427634	2004.1.1.23 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom	0.70	63.0	5.62e-01	96.6%	78.8%
3653891	2004.1.1.428 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom, Helicase_C, HDA2-3	0.70	63.0	4.30e-01	95.5%	46.5%
3429152	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.70	63.0	6.10e-01	100.0%	86.5%
3415391	2004.1.1.364 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD+Helicase_C	0.69	64.0	4.43e-01	100.0%	31.4%
3640083	2004.1.1.185 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11,AAA_12	0.69	64.0	5.04e-01	98.9%	71.4%
3743424	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.69	64.0	6.12e-01	100.0%	86.3%
3335090	2004.1.1.23 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom	0.69	63.0	5.61e-01	96.6%	82.5%
3627919	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.69	64.0	4.11e-01	99.4%	55.7%
4003022	2004.1.1.428 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom, Helicase_C, HDA2-3	0.69	63.0	4.38e-01	99.4%	74.9%
3273397	2004.1.1.629 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom, Helicase_C, ResIII	0.69	64.0	4.25e-01	99.4%	70.8%
3467752	2004.1.1.23 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom	0.69	62.0	5.25e-01	96.6%	85.7%
4077893	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.68	63.0	4.43e-01	98.9%	53.8%
4941322	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.68	57.0	4.68e-01	87.5%	89.8%
3315112	2004.1.1.364 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD+Helicase_C	0.68	63.0	4.61e-01	98.9%	64.0%
None	—		0.68	63.0	4.03e-01	99.4%	35.2%
3928290	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.68	56.0	5.10e-01	85.8%	96.4%
3821734	2004.1.1.364 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD+Helicase_C	0.68	63.0	4.51e-01	98.9%	59.4%
3496639	2004.1.1.24 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom,Helicase_C	0.68	63.0	4.28e-01	99.4%	76.3%
5045020	2004.1.1.30 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C	0.68	63.0	5.33e-01	100.0%	98.2%
3179008	2004.1.1.23 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom	0.67	62.0	4.95e-01	98.9%	71.8%
4018832	2004.1.1.29 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD	0.67	61.0	5.59e-01	98.3%	88.7%
3940856	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.67	52.0	5.73e-01	81.8%	100.0%
4381437	2004.1.1.159 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mur_ligase_M	0.62	51.0	4.97e-01	85.8%	87.4%
4953866	2004.1.1.159 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mur_ligase_M	0.61	51.0	4.73e-01	87.5%	90.7%
5023089	2004.1.1.159 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mur_ligase_M	0.61	51.0	4.96e-01	88.6%	94.2%
4971131	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.60	54.0	3.87e-01	97.2%	50.8%
3839226	2004.1.1.159 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mur_ligase_M	0.58	48.0	4.46e-01	88.6%	89.8%
None	—		0.57	52.0	4.80e-01	100.0%	80.0%
4979416	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.54	48.0	3.54e-01	98.3%	49.9%
169081	7579.1.1.6 ↗	a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1	0.52	44.0	4.03e-01	91.5%	93.5%
5056796	7501.1.1.2 ↗	a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C	0.51	44.0	4.26e-01	94.3%	94.0%
3802403	2004.5.1.3 ↗	a/b three-layered sandwiches › P-loop domains-like › Differentially expressed in normal cells and neoplasia (DENN) domain › Differentially expressed in normal cells and neoplasia (DENN) domain › DENN	0.50	43.0	3.78e-01	97.7%	62.4%

D3 high residues 788-908

PDB

Domain cluster: rep: EU399241.1__ABY90404.1__HAPgp36__00036__D1029-1180

CATH (44)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5hvqC01	3.90.1150.220	Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 ›	0.69	44.0	5.14e-01	81.8%	95.0%
2cpmA00	3.30.1370.50	Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › R3H-like domain	0.65	34.0	3.81e-01	82.6%	64.9%
2dchX01	3.10.28.10	Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases	0.63	37.0	4.17e-01	90.9%	75.3%
1ef0B02	3.10.28.10	Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases	0.62	37.0	3.20e-01	86.0%	38.3%
1ug8A00	3.30.1370.50	Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › R3H-like domain	0.61	35.0	4.11e-01	82.6%	79.3%
4hqeA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.61	37.0	3.95e-01	86.0%	68.6%
3rrkA03	3.30.70.2750	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.60	28.0	3.41e-01	72.7%	67.6%
1dq3A04	3.10.28.10	Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases	0.60	38.0	3.93e-01	92.6%	67.5%
4p55B00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.59	45.0	4.90e-01	86.0%	100.0%
2yweA03	3.30.70.870	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3	0.59	29.0	3.39e-01	71.9%	65.9%
2p4wA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.59	38.0	4.07e-01	93.4%	75.7%
1m0sA02	3.30.70.260	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain	0.59	27.0	3.49e-01	72.7%	73.6%
3l7wA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.59	38.0	4.06e-01	87.6%	74.3%
3l9fA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.58	37.0	4.20e-01	85.1%	85.4%
1o51A00	3.30.70.120	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.58	31.0	3.56e-01	75.2%	68.5%
2jzxA02	3.30.1370.10	Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1	0.58	29.0	3.50e-01	73.6%	70.9%
2qbyB03	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.58	36.0	4.00e-01	85.1%	81.3%
1j4wA01	3.30.1370.10	Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1	0.57	29.0	3.50e-01	71.1%	74.3%
5dymA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.57	37.0	4.10e-01	88.4%	82.3%
2l48A00	3.30.70.2030	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.57	29.0	3.39e-01	90.1%	68.2%
2dqlA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.57	37.0	3.85e-01	85.1%	69.6%
2dgrA01	3.30.1370.10	Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1	0.56	27.0	3.43e-01	71.1%	77.6%
1khmA00	3.30.1370.10	Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1	0.56	29.0	3.27e-01	71.9%	62.9%
6kf9G01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.56	35.0	4.11e-01	87.6%	93.9%
2axyA00	3.30.1370.10	Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1	0.56	27.0	3.34e-01	73.6%	73.6%
2anrA02	3.30.1370.10	Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1	0.55	27.0	3.29e-01	72.7%	70.7%
5w2fA01	3.30.780.10	Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain	0.55	30.0	3.42e-01	74.4%	70.9%
2dt9A02	3.30.70.260	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain	0.55	27.0	3.31e-01	70.2%	72.2%
6abqB00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.54	37.0	3.89e-01	89.3%	80.2%
2f1fA02	3.30.70.1150	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2	0.53	30.0	3.53e-01	74.4%	83.3%
3im8A02	3.30.70.250	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding	0.53	27.0	3.30e-01	71.9%	78.1%
4esbA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.53	38.0	4.04e-01	95.0%	87.4%
7xc2A02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.52	36.0	3.86e-01	92.6%	82.1%
1fpqA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.52	36.0	3.61e-01	87.6%	67.4%
2ctjA00	3.30.1370.10	Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1	0.52	27.0	2.94e-01	71.1%	57.9%
1bm9A00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.52	38.0	3.83e-01	95.0%	77.5%
1kyzA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.52	32.0	3.46e-01	83.5%	71.8%
1sfxB00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.51	34.0	3.64e-01	95.0%	78.8%
3r0aA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.51	38.0	3.84e-01	96.7%	79.2%
2zihC00	1.10.3630.10	Mainly Alpha › Orthogonal Bundle › yeast vps74-n-term truncation variant fold › yeast vps74-n-term truncation variant domain like	0.51	43.0	3.37e-01	94.2%	63.1%
1b24A01	3.10.28.10	Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases	0.51	34.0	3.80e-01	86.0%	88.4%
2p92A00	3.30.70.1490	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp	0.51	29.0	3.15e-01	77.7%	67.4%
3zxoA00	3.30.565.10	Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain	0.50	37.0	3.70e-01	93.4%	74.4%
2cpxA01	3.30.70.330	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain	0.50	26.0	3.03e-01	71.9%	70.9%

ECOD (54)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3679905	320.1.1.1 ↗	a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H	0.65	38.0	3.91e-01	86.8%	59.1%
5025840	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.65	42.0	4.59e-01	83.5%	78.0%
3602264	242.1.1.7 ↗	a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3	0.65	39.0	4.54e-01	88.4%	84.7%
4992480	242.1.1.0 ↗	a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases	0.64	38.0	4.37e-01	88.4%	78.9%
5050784	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.61	40.0	4.42e-01	90.9%	87.8%
4997255	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.60	40.0	4.35e-01	88.4%	81.0%
5017942	101.1.2.14 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_5	0.59	36.0	3.94e-01	90.9%	73.0%
4487383	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.59	40.0	4.19e-01	86.0%	76.4%
5023773	101.1.2.31 ↗	alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha	0.59	43.0	3.82e-01	95.9%	52.6%
4978090	101.1.2.48 ↗	alpha arrays › HTH › HTH › winged helix domain › PadR	0.59	39.0	3.23e-01	88.4%	37.7%
3877940	327.11.2.0 ↗	a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I)	0.58	29.0	3.61e-01	71.1%	78.6%
4961841	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.58	40.0	3.91e-01	88.4%	65.4%
4963469	242.1.1.0 ↗	a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases	0.57	38.0	4.04e-01	89.3%	78.1%
5001284	101.1.2.48 ↗	alpha arrays › HTH › HTH › winged helix domain › PadR	0.57	38.0	3.52e-01	88.4%	51.2%
3797522	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.57	38.0	4.09e-01	84.3%	81.0%
164542	101.1.2.48 ↗	alpha arrays › HTH › HTH › winged helix domain › PadR	0.57	37.0	3.85e-01	85.1%	69.6%
4976773	101.1.2.275 ↗	alpha arrays › HTH › HTH › winged helix domain › DUF1495	0.57	37.0	3.85e-01	90.9%	71.8%
4401786	101.1.2.31 ↗	alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha	0.56	40.0	4.26e-01	96.7%	85.7%
3739592	327.11.2.1 ↗	a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1	0.56	28.0	3.35e-01	73.6%	72.0%
3400190	101.1.2.24 ↗	alpha arrays › HTH › HTH › winged helix domain › MAGE	0.55	42.0	4.14e-01	91.7%	75.4%
3587894	101.1.2.49 ↗	alpha arrays › HTH › HTH › winged helix domain › PadR,Vir_act_alpha_C	0.55	37.0	3.27e-01	88.4%	46.3%
4585912	101.1.2.603 ↗	alpha arrays › HTH › HTH › winged helix domain › RNA_pol_Rpc82, HTH_9	0.55	39.0	2.79e-01	93.4%	23.5%
5035685	101.1.2.48 ↗	alpha arrays › HTH › HTH › winged helix domain › PadR	0.54	38.0	3.79e-01	88.4%	68.5%
4941287	101.1.2.31 ↗	alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha	0.54	36.0	3.96e-01	93.4%	88.9%
4966185	101.1.2.26 ↗	alpha arrays › HTH › HTH › winged helix domain › HxlR	0.54	34.0	3.79e-01	88.4%	80.0%
4966215	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.54	35.0	3.17e-01	88.4%	46.1%
4314672	101.1.2.101 ↗	alpha arrays › HTH › HTH › winged helix domain › Cdc6_C	0.54	36.0	3.80e-01	87.6%	77.1%
5058727	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.54	38.0	3.57e-01	89.3%	60.0%
3213701	327.11.2.1 ↗	a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1	0.54	27.0	3.08e-01	71.1%	61.1%
5070883	101.1.2.31 ↗	alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha	0.53	37.0	4.09e-01	93.4%	95.6%
4926994	101.1.2.150 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_45	0.53	38.0	4.10e-01	100.0%	88.5%
3468397	101.1.2.386 ↗	alpha arrays › HTH › HTH › winged helix domain › WH_DRP	0.53	42.0	4.22e-01	90.1%	85.8%
4014683	101.1.2.24 ↗	alpha arrays › HTH › HTH › winged helix domain › MAGE	0.52	40.0	3.93e-01	95.9%	75.4%
5041543	101.1.2.135 ↗	alpha arrays › HTH › HTH › winged helix domain › MarR_2	0.52	37.0	3.59e-01	93.4%	63.6%
5054122	101.1.2.31 ↗	alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha	0.52	36.0	3.34e-01	94.2%	53.1%
3633871	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.52	38.0	3.25e-01	89.3%	44.0%
3798603	327.11.2.0 ↗	a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I)	0.52	27.0	3.05e-01	74.4%	62.9%
5016748	101.1.2.30 ↗	alpha arrays › HTH › HTH › winged helix domain › TrmB	0.52	37.0	3.71e-01	93.4%	73.3%
5070663	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.52	35.0	3.42e-01	88.4%	60.0%
4981949	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.52	34.0	3.96e-01	88.4%	100.0%
5025451	101.1.2.143 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_34	0.52	37.0	3.88e-01	94.2%	81.8%
3782190	101.1.2.65 ↗	alpha arrays › HTH › HTH › winged helix domain › Rad21_Rec8	0.52	39.0	4.06e-01	86.0%	86.0%
5069274	101.1.2.135 ↗	alpha arrays › HTH › HTH › winged helix domain › MarR_2	0.51	37.0	3.78e-01	93.4%	78.3%
5033035	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.51	36.0	3.72e-01	91.7%	75.4%
4974447	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.51	36.0	3.67e-01	94.2%	73.3%
4959456	101.1.2.48 ↗	alpha arrays › HTH › HTH › winged helix domain › PadR	0.51	35.0	3.22e-01	93.4%	50.6%
3451526	101.1.2.528 ↗	alpha arrays › HTH › HTH › winged helix domain › PF31130	0.51	41.0	4.34e-01	89.3%	100.0%
5029277	101.1.2.31 ↗	alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha	0.51	37.0	3.95e-01	93.4%	88.6%
3926827	101.1.2.394 ↗	alpha arrays › HTH › HTH › winged helix domain › eWH_GTF3C1	0.51	44.0	2.95e-01	100.0%	48.9%
5055444	101.1.2.31 ↗	alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha	0.51	35.0	3.72e-01	96.7%	84.0%
4134403	109.4.1.613 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Asp_Glu_race_2	0.51	46.0	3.17e-01	98.3%	42.5%
5001098	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.51	33.0	3.73e-01	91.7%	90.0%
4985036	101.1.2.31 ↗	alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha	0.50	35.0	3.18e-01	93.4%	50.6%
2391543	101.1.2.48 ↗	alpha arrays › HTH › HTH › winged helix domain › PadR	0.50	36.0	3.13e-01	95.9%	46.2%

D4 medium residues 7-179

PDB

Domain cluster: representative

CATH (5)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1t5oA01	1.20.120.420	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1	0.61	34.0	3.73e-01	79.8%	64.5%
2r5sA02	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.59	32.0	4.19e-01	79.8%	100.0%
4f5cA04	1.25.50.20	Mainly Alpha › Alpha Horseshoe › Zincin-like fold ›	0.58	37.0	3.04e-01	100.0%	33.4%
3dmyA01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.53	24.0	2.64e-01	87.9%	46.9%
4yvoA00	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.51	33.0	3.87e-01	90.8%	94.1%

ECOD (3)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3278268	601.1.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin	0.56	39.0	3.95e-01	83.8%	69.7%
3504185	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.54	34.0	3.83e-01	87.9%	82.3%
3475614	186.2.1.1 ↗	alpha arrays › lambda integrase-N-like › VEFS domain › VEFS domain › VEFS-Box	0.52	37.0	4.18e-01	94.8%	95.4%

D5 medium residues 644-705

PDB

Domain cluster: representative

CATH (12)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4hteA03	1.10.167.30	Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 ›	0.69	37.0	3.36e-01	100.0%	40.0%
1lp1A00	1.20.5.420	Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C	0.67	35.0	3.68e-01	96.8%	56.4%
3e3vA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.64	34.0	3.67e-01	100.0%	58.5%
2p0tA02	1.10.60.30	Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › PSPTO4464-like domains	0.60	47.0	4.47e-01	85.5%	72.2%
4hojA02	1.20.1050.10	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.56	44.0	3.70e-01	83.9%	62.1%
2oblA02	1.20.1270.330	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 ›	0.56	46.0	4.43e-01	98.4%	98.6%
1vt0M05	6.10.280.90	Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.54	36.0	3.40e-01	80.6%	56.8%
2qf9A01	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.53	41.0	3.09e-01	100.0%	33.3%
1jr8A00	1.20.120.310	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ERV/ALR sulfhydryl oxidase domain	0.53	46.0	3.91e-01	100.0%	78.1%
1oqcA00	1.20.120.310	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ERV/ALR sulfhydryl oxidase domain	0.51	45.0	3.70e-01	100.0%	67.0%
3gwlA00	1.20.120.310	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ERV/ALR sulfhydryl oxidase domain	0.50	43.0	3.69e-01	100.0%	77.4%
1sz9C00	1.25.40.90	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat ›	0.50	39.0	3.03e-01	85.5%	65.7%

ECOD (8)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4031266	632.2.1.1 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains › GA	0.76	39.0	4.23e-01	100.0%	59.3%
1503071	632.2.1.1 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains › GA	0.72	37.0	3.94e-01	100.0%	55.4%
2100256	1070.1.1.1 ↗	alpha complex topology › CRISPR-associated endonuclease first helical domain › CRISPR-associated endonuclease Cpf1 first helical domain › CRISPR-associated endonuclease Cpf1 first helical domain › REC1	0.55	47.0	3.26e-01	100.0%	95.9%
3476012	109.4.1.1469 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Death_MADD	0.55	46.0	3.10e-01	91.9%	29.1%
4946202	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.54	43.0	3.93e-01	85.5%	70.0%
3711919	3187.1.1.0 ↗	alpha bundles › Microtubule-Binding Domain of Flagellar Dynein › Microtubule-Binding Domain of Flagellar Dynein › Microtubule-Binding Domain of Flagellar Dynein	0.53	45.0	3.34e-01	100.0%	41.7%
4573266	5069.1.3.61 ↗	alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › ResB	0.52	43.0	3.36e-01	100.0%	40.7%
3697681	4156.1.1.0 ↗	alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like	0.51	35.0	2.59e-01	100.0%	25.6%

D6 medium residues 737-787

PDB

Domain cluster: representative

CATH (73)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4llgM00	3.10.20.510	Alpha Beta › Roll › Ubiquitin-like (UB roll) › RNA polymerase inhibitor	0.77	64.0	6.47e-01	94.1%	100.0%
6b9tF02	2.60.120.10	Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls	0.72	51.0	4.02e-01	92.2%	35.8%
4u7cB04	3.30.1490.100	Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › DNA polymerase, Y-family, little finger domain	0.72	62.0	4.89e-01	100.0%	59.6%
6l4cA01	2.60.120.10	Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls	0.71	52.0	3.55e-01	100.0%	22.3%
3bnkA00	2.30.110.10	Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A	0.70	61.0	4.18e-01	100.0%	84.4%
2jxtA01	3.10.20.10	Alpha Beta › Roll › Ubiquitin-like (UB roll) ›	0.70	56.0	5.08e-01	96.1%	75.0%
1unnC00	3.30.1490.100	Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › DNA polymerase, Y-family, little finger domain	0.70	58.0	4.61e-01	98.0%	49.5%
2eddA01	2.60.40.10	Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins	0.69	54.0	4.31e-01	100.0%	41.1%
4lejA01	2.60.120.10	Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls	0.69	51.0	3.51e-01	100.0%	23.0%
3mfiA04	3.30.1490.100	Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › DNA polymerase, Y-family, little finger domain	0.69	58.0	4.55e-01	100.0%	58.0%
2xnjA01	2.40.30.10	Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors	0.68	56.0	4.50e-01	94.1%	69.2%
6mv2A02	2.40.30.10	Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors	0.68	55.0	4.42e-01	92.2%	68.6%
4ybnB00	2.30.110.10	Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A	0.68	60.0	3.97e-01	100.0%	90.7%
4emeC02	2.30.250.10	Mainly Beta › Roll › Aminopeptidase i, Domain 2 › Aminopeptidase i, Domain 2	0.68	55.0	4.17e-01	96.1%	74.1%
3u5wA00	2.30.110.10	Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A	0.68	55.0	4.16e-01	92.2%	42.1%
3zoqC00	6.20.250.30	Special › Other non-globular › Double Stranded RNA Binding Domain ›	0.67	55.0	5.44e-01	100.0%	90.6%
1mw7A02	3.30.70.980	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › YebC, transcriptional regulation domain	0.67	50.0	4.32e-01	84.3%	54.0%
1cauA00	2.60.120.10	Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls	0.67	51.0	3.48e-01	100.0%	23.2%
2a2jA00	2.30.110.10	Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A	0.67	59.0	3.92e-01	100.0%	29.1%
2v5yA04	2.60.40.10	Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins	0.67	57.0	4.65e-01	100.0%	51.0%
2eixA01	2.40.30.10	Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors	0.66	54.0	4.31e-01	92.2%	58.5%
3ec6A00	2.30.110.10	Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A	0.66	56.0	4.25e-01	98.0%	45.3%
4h3wA02	2.60.120.1260	Mainly Beta › Sandwich › Jelly Rolls ›	0.65	55.0	4.03e-01	100.0%	40.8%
5cadA01	2.60.120.10	Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls	0.65	48.0	3.28e-01	100.0%	21.2%
2bnmA02	2.60.120.10	Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls	0.65	48.0	3.67e-01	92.2%	34.2%
1ywhC03	2.10.60.10	Mainly Beta › Ribbon › CD59 › CD59	0.65	55.0	4.65e-01	98.0%	58.0%
4ll1C02	2.60.40.640	Mainly Beta › Sandwich › Immunoglobulin-like ›	0.65	58.0	4.19e-01	100.0%	52.1%
1qysA00	3.30.1710.10	Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein	0.65	52.0	4.40e-01	94.1%	57.6%
3db0B00	2.30.110.10	Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A	0.65	55.0	4.20e-01	98.0%	45.2%
1ln0A00	3.40.1440.10	Alpha Beta › 3-Layer(aba) Sandwich › GIY-YIG endonuclease › GIY-YIG endonuclease	0.64	52.0	4.45e-01	98.0%	75.0%
2jvfA00	3.30.1710.10	Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein	0.64	51.0	4.28e-01	92.2%	57.4%
1xf1A05	2.60.40.10	Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins	0.64	54.0	4.39e-01	98.0%	66.3%
1ca1A02	2.60.60.20	Mainly Beta › Sandwich › Lipoxygenase-1 › PLAT/LH2 domain	0.63	53.0	4.15e-01	100.0%	51.7%
4yo1A01	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.63	50.0	4.27e-01	92.2%	56.2%
4kyzA00	3.30.70.600	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10	0.62	51.0	3.70e-01	100.0%	89.8%
2llzA01	3.30.70.2360	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.62	48.0	4.07e-01	88.2%	91.1%
2hq9B00	2.30.110.10	Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A	0.62	53.0	3.97e-01	100.0%	40.1%
7y8sB01	2.60.40.10	Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins	0.62	49.0	4.25e-01	100.0%	55.2%
2rftA02	3.90.209.20	Alpha Beta › Alpha-Beta Complex › Hemagglutinin (Ha1 Chain); Chain: A; domain 1 › Haemagglutinin, alpha/beta domain, HA1 chain	0.62	52.0	3.39e-01	98.0%	38.9%
4ccjA01	2.60.120.650	Mainly Beta › Sandwich › Jelly Rolls › Cupin	0.61	45.0	2.93e-01	82.4%	33.7%
1w99A02	2.60.120.260	Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like	0.60	52.0	3.56e-01	100.0%	38.2%
4ekjA01	2.60.40.1500	Mainly Beta › Sandwich › Immunoglobulin-like › Glycosyl hydrolase domain; family 39	0.60	48.0	3.49e-01	92.2%	51.3%
1nh8A03	3.30.70.120	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.59	46.0	4.35e-01	92.2%	100.0%
5of3A00	3.90.920.10	Alpha Beta › Alpha-Beta Complex › DNA primase, PRIM domain › DNA primase, PRIM domain	0.59	46.0	2.98e-01	100.0%	19.4%
2xskA00	2.60.40.2420	Mainly Beta › Sandwich › Immunoglobulin-like ›	0.59	50.0	4.16e-01	100.0%	61.1%
4n0rA01	2.60.40.10	Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins	0.59	47.0	4.08e-01	92.2%	56.5%
1xreA02	3.55.40.20	Alpha Beta › 3-Layer(bab) Sandwich › minor pseudopilin epsh fold › Iron/manganese superoxide dismutase, C-terminal domain	0.58	49.0	3.90e-01	100.0%	44.6%
5h4eA01	2.60.110.10	Mainly Beta › Sandwich › Thaumatin › Thaumatin	0.58	48.0	3.18e-01	98.0%	48.1%
6z9cA01	2.60.40.1470	Mainly Beta › Sandwich › Immunoglobulin-like › ApaG domain	0.58	49.0	3.81e-01	100.0%	51.6%
1d0nA06	3.40.20.10	Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin	0.58	41.0	3.21e-01	92.2%	30.7%
5cvmA00	3.90.70.10	Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases	0.58	51.0	3.14e-01	100.0%	61.0%
6kwzA00	3.40.20.10	Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin	0.57	49.0	4.01e-01	98.0%	75.5%
4d0qA00	2.60.120.260	Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like	0.57	48.0	3.50e-01	100.0%	52.2%
7neaA01	3.30.470.10	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › Aminotransferase class 4, branched-chain amino acid transferase, N-terminal domain	0.57	39.0	3.12e-01	76.5%	82.6%
1xdnA02	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.56	50.0	3.52e-01	100.0%	71.0%
3ddcB00	3.10.20.90	Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1	0.56	46.0	3.61e-01	100.0%	65.4%
5exvC00	3.40.1570.10	Alpha Beta › 3-Layer(aba) Sandwich › Heme iron utilization protein-like fold › HemS/ChuS/ChuX like domains	0.56	48.0	3.42e-01	100.0%	56.4%
5ygbA01	2.40.50.90	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) ›	0.56	37.0	2.91e-01	70.6%	45.1%
6dgiA02	3.30.470.20	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain	0.56	48.0	3.53e-01	100.0%	59.0%
2pjyC00	2.10.60.10	Mainly Beta › Ribbon › CD59 › CD59	0.56	48.0	4.15e-01	96.1%	67.1%
3au4A02	3.10.20.90	Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1	0.56	46.0	3.80e-01	92.2%	71.3%
2irmA00	3.60.40.10	Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain	0.56	47.0	2.90e-01	100.0%	91.2%
3d0jA00	2.60.120.10	Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls	0.56	44.0	3.29e-01	90.2%	44.2%
1g13A00	2.70.220.10	Mainly Beta › Distorted Sandwich › Ganglioside M2 Activator Protein; Chain: A, › Ganglioside GM2 activator	0.55	46.0	3.35e-01	100.0%	61.1%
2kvkA00	3.40.20.10	Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin	0.55	43.0	3.24e-01	92.2%	33.3%
4harA00	3.10.50.50	Alpha Beta › Roll › Chitinase A; domain 3 › Rubella virus capsid protein	0.54	44.0	3.59e-01	92.2%	94.9%
6l4lA01	3.10.310.10	Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1	0.54	43.0	3.35e-01	90.2%	100.0%
7pupA01	3.30.470.20	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain	0.54	46.0	3.07e-01	100.0%	61.9%
6kbyA00	3.40.710.10	Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily	0.53	37.0	2.35e-01	78.4%	72.9%
1r0uA00	2.40.128.20	Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain	0.53	44.0	3.35e-01	100.0%	90.1%
7bjkA02	3.55.40.20	Alpha Beta › 3-Layer(bab) Sandwich › minor pseudopilin epsh fold › Iron/manganese superoxide dismutase, C-terminal domain	0.53	41.0	3.38e-01	100.0%	43.4%
3webA00	2.60.40.770	Mainly Beta › Sandwich › Immunoglobulin-like ›	0.52	42.0	3.26e-01	98.0%	51.5%
3e0jB00	3.90.1030.20	Alpha Beta › Alpha-Beta Complex › 50s Ribosomal Protein L17; Chain: A, › DNA polymerase delta, p66 (Cdc27) subunit, wHTH domain	0.52	42.0	3.20e-01	98.0%	51.0%

ECOD (80)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4964337	3115.5.1.1 ↗	a+b two layers › GP2-like › phenylacetate-CoA oxygenase subunit PaaB › phenylacetate-CoA oxygenase subunit PaaB › PaaB	0.78	64.0	6.25e-01	90.2%	90.9%
4013514	3115.1.1.0 ↗	a+b two layers › GP2-like › RplX-like › RplX-like	0.77	65.0	5.19e-01	96.1%	58.1%
5000510	3115.1.1.1 ↗	a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A	0.77	66.0	5.84e-01	98.0%	96.0%
3216210	3115.1.1.0 ↗	a+b two layers › GP2-like › RplX-like › RplX-like	0.76	60.0	6.12e-01	90.2%	100.0%
4939739	3115.1.1.1 ↗	a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A	0.76	64.0	6.20e-01	100.0%	96.6%
5080205	3115.1.1.0 ↗	a+b two layers › GP2-like › RplX-like › RplX-like	0.76	65.0	6.54e-01	98.0%	100.0%
4004704	3115.6.1.2 ↗	a+b two layers › GP2-like › Bacterial RNA polymerase subunit epsilon › Bacterial RNA polymerase subunit epsilon › PF28597	0.75	60.0	6.31e-01	90.2%	100.0%
4995671	3115.1.1.12 ↗	a+b two layers › GP2-like › RplX-like › RplX-like › PF30567	0.75	63.0	6.42e-01	98.0%	100.0%
4160542	3115.1.1.1 ↗	a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A	0.75	61.0	5.91e-01	94.1%	96.6%
3969006	3115.6.1.2 ↗	a+b two layers › GP2-like › Bacterial RNA polymerase subunit epsilon › Bacterial RNA polymerase subunit epsilon › PF28597	0.75	60.0	6.27e-01	90.2%	100.0%
3968122	3115.6.1.2 ↗	a+b two layers › GP2-like › Bacterial RNA polymerase subunit epsilon › Bacterial RNA polymerase subunit epsilon › PF28597	0.75	59.0	6.20e-01	90.2%	100.0%
4007508	3115.6.1.2 ↗	a+b two layers › GP2-like › Bacterial RNA polymerase subunit epsilon › Bacterial RNA polymerase subunit epsilon › PF28597	0.74	61.0	6.20e-01	96.1%	94.0%
5067865	3115.1.1.0 ↗	a+b two layers › GP2-like › RplX-like › RplX-like	0.73	61.0	5.56e-01	96.1%	87.1%
5081134	3986.2.1.0 ↗	a+b two layers › GTP-binding protein lepA C-terminal domain-like › Antitoxin Dmd › Antitoxin Dmd	0.73	59.0	5.65e-01	90.2%	83.3%
4995672	3115.1.1.0 ↗	a+b two layers › GP2-like › RplX-like › RplX-like	0.73	59.0	5.98e-01	98.0%	96.0%
4951473	3115.1.1.1 ↗	a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A	0.73	62.0	5.90e-01	100.0%	96.8%
4967222	3115.1.1.1 ↗	a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A	0.73	60.0	5.82e-01	100.0%	96.7%
3975705	3115.6.1.0 ↗	a+b two layers › GP2-like › Bacterial RNA polymerase subunit epsilon › Bacterial RNA polymerase subunit epsilon	0.72	59.0	5.99e-01	96.1%	94.0%
146929	3115.3.1.1 ↗	a+b two layers › GP2-like › P56 › P56 › UDG-inhib_P56	0.72	59.0	5.79e-01	98.0%	85.7%
4463006	3115.2.1.0 ↗	a+b two layers › GP2-like › GP2 › GP2	0.72	56.0	5.82e-01	86.3%	100.0%
3867707	11.1.1.2 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › fn3	0.72	63.0	4.86e-01	100.0%	46.1%
5065436	3115.1.1.0 ↗	a+b two layers › GP2-like › RplX-like › RplX-like	0.71	60.0	5.67e-01	98.0%	95.3%
4969863	3115.1.1.1 ↗	a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A	0.71	58.0	5.27e-01	98.0%	80.0%
3264847	2492.1.1.36 ↗	a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like › ODR4-like	0.70	56.0	3.75e-01	90.2%	22.9%
3414064	379.1.1.0 ↗	few secondary structure elements › Kazal-type serine protease inhibitors-like › Kazal-type serine protease inhibitors › Kazal-type serine protease inhibitors	0.70	53.0	5.19e-01	92.2%	78.2%
4016088	821.1.1.3 ↗	a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › T5orf172	0.69	57.0	4.63e-01	100.0%	46.7%
4959407	304.163.1.3 ↗	a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain › PF31118	0.69	57.0	5.80e-01	98.0%	94.0%
4394754	304.5.1.7 ↗	a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › DUF2179	0.68	58.0	4.88e-01	98.0%	81.1%
5747	4007.1.1.1 ↗	a+b two layers › a+b domain in YebC-like proteins › a+b domain in YebC-like proteins › a+b domain in YebC-like proteins › Transcrip_reg	0.68	51.0	5.08e-01	86.3%	88.9%
3594101	301.1.1.0 ↗	a+b three layers › Bacillus chorismate mutase-like › L30e-like › L30e-like	0.67	59.0	4.21e-01	100.0%	34.8%
3480696	382.1.1.0 ↗	few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like	0.67	56.0	4.74e-01	98.0%	56.5%
4009311	4187.2.1.0 ↗	a+b two layers › NosL/MerB-like › DUF2233 › DUF2233	0.67	51.0	4.87e-01	90.2%	72.3%
3959600	304.5.1.0 ↗	a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like	0.67	54.0	4.85e-01	94.1%	97.3%
3942988	4187.2.1.1 ↗	a+b two layers › NosL/MerB-like › DUF2233 › DUF2233 › NAGPA	0.66	51.0	4.81e-01	88.2%	70.8%
3396683	382.1.1.0 ↗	few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like	0.66	54.0	4.82e-01	98.0%	67.1%
3285401	3986.2.1.0 ↗	a+b two layers › GTP-binding protein lepA C-terminal domain-like › Antitoxin Dmd › Antitoxin Dmd	0.66	56.0	4.98e-01	98.0%	69.3%
5000686	862.1.1.1 ↗	a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › DNA_primase_S	0.66	56.0	3.55e-01	100.0%	48.1%
5010216	304.4.1.0 ↗	a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel	0.66	54.0	4.96e-01	96.1%	92.9%
4105022	304.5.1.7 ↗	a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › DUF2179	0.65	54.0	4.58e-01	98.0%	84.4%
3405824	1.1.7.7 ↗	beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › FAD_binding_6	0.65	54.0	4.26e-01	100.0%	62.5%
3390562	382.1.1.0 ↗	few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like	0.64	53.0	4.85e-01	96.1%	71.4%
3755511	11.1.5.12 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › STAT_bind	0.64	56.0	4.44e-01	100.0%	67.6%
5075402	210.1.3.3 ↗	a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_4	0.64	53.0	3.40e-01	100.0%	18.2%
4654074	304.5.1.0 ↗	a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like	0.64	55.0	4.58e-01	98.0%	78.9%
3415271	382.1.1.0 ↗	few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like	0.63	48.0	4.33e-01	90.2%	62.5%
3432908	5.1.3.118 ↗	beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_3	0.63	55.0	3.30e-01	96.1%	98.8%
3067246	3115.3.1.1 ↗	a+b two layers › GP2-like › P56 › P56 › UDG-inhib_P56	0.63	51.0	5.02e-01	100.0%	89.3%
4946875	862.1.1.1 ↗	a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › DNA_primase_S	0.62	52.0	3.36e-01	100.0%	23.8%
4867320	221.1.1.66 ↗	a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › PIK3CG_ABD	0.62	49.0	4.06e-01	92.2%	89.2%
3802249	109.4.1.1291 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, DYW_deaminase, E_motif	0.62	49.0	2.80e-01	88.2%	17.2%
4955225	210.1.3.3 ↗	a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_4	0.62	51.0	3.37e-01	100.0%	39.6%
3525173	72.1.1.1 ↗	beta sandwiches › gamma-Crystallin-like › gamma-Crystallin-like › gamma-Crystallin-like › Crystall	0.62	48.0	4.22e-01	100.0%	55.3%
3320430	10.32.1.0 ↗	beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like	0.61	51.0	3.94e-01	100.0%	50.8%
3494105	221.1.1.64 ↗	a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › Formin_GBD_N	0.61	48.0	4.31e-01	94.1%	82.5%
3958897	4187.2.1.0 ↗	a+b two layers › NosL/MerB-like › DUF2233 › DUF2233	0.61	51.0	4.01e-01	100.0%	69.2%
3672250	207.1.1.116 ↗	beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_FBXL15	0.61	46.0	3.30e-01	92.2%	25.3%
3405565	221.1.1.6 ↗	a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › RA	0.61	50.0	4.19e-01	98.0%	51.6%
3929801	221.1.1.6 ↗	a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › RA	0.61	49.0	4.07e-01	92.2%	85.3%
3829568	109.4.1.1383 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, DYW_deaminase, Eplus_motif, E_motif	0.61	47.0	2.68e-01	88.2%	15.4%
3781274	210.2.1.1 ↗	a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C	0.60	53.0	3.15e-01	100.0%	48.7%
3834151	109.4.1.3495 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, DYW_deaminase, PPR_long, E_motif, TPR_24	0.60	46.0	2.66e-01	86.3%	17.4%
2006900	302.4.1.0 ↗	a+b two layers › Reverse ferredoxin › a+b domain in Acetophenone carboxylase (Apc) alpha subunit › a+b domain in Acetophenone carboxylase (Apc) alpha subunit	0.60	49.0	4.08e-01	100.0%	54.8%
3551231	221.1.1.87 ↗	a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › FERM_N_2	0.59	49.0	3.98e-01	98.0%	61.9%
3400735	379.1.1.3 ↗	few secondary structure elements › Kazal-type serine protease inhibitors-like › Kazal-type serine protease inhibitors › Kazal-type serine protease inhibitors › Kazal_2	0.59	42.0	4.21e-01	98.0%	76.4%
5011866	210.1.3.3 ↗	a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_4	0.59	48.0	3.24e-01	100.0%	41.3%
3218957	221.1.1.6 ↗	a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › RA	0.58	48.0	3.83e-01	98.0%	58.3%
3704468	221.1.1.0 ↗	a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like	0.58	47.0	3.76e-01	98.0%	42.7%
3825377	109.4.1.1291 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, DYW_deaminase, E_motif	0.58	44.0	2.51e-01	86.3%	13.7%
3434515	109.4.1.2925 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, DYW_deaminase, PPR_long, E_motif	0.58	45.0	2.54e-01	88.2%	13.6%
3920384	221.1.1.6 ↗	a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › RA	0.58	48.0	3.61e-01	98.0%	68.3%
3378740	109.4.1.1291 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, DYW_deaminase, E_motif	0.57	45.0	2.45e-01	88.2%	10.1%
3488019	221.1.1.6 ↗	a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › RA	0.57	46.0	3.51e-01	100.0%	63.9%
3622256	219.1.1.3 ↗	a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH	0.56	49.0	3.47e-01	98.0%	36.1%
3771226	382.1.1.3 ↗	few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like › Activin_recp	0.55	46.0	3.90e-01	98.0%	57.8%
3548439	11.1.1.41 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Arrestin_C	0.55	48.0	3.40e-01	98.0%	49.7%
4879916	382.1.1.3 ↗	few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like › Activin_recp	0.55	45.0	4.06e-01	98.0%	70.1%
3929515	382.1.1.21 ↗	few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like › PF28966	0.54	46.0	3.65e-01	98.0%	63.8%
3599827	11.1.1.0 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like	0.53	44.0	3.27e-01	100.0%	46.5%
4030283	247.1.1.11 ↗	a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2	0.53	41.0	2.44e-01	92.2%	57.6%
3366506	10.2.1.0 ↗	beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins)	0.52	44.0	3.13e-01	100.0%	65.1%