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CPXV036_protein

Euk-Vir

Cowpox_virus

CPXV036_protein__NP_619825__Cowpox_virus__10243

Identity

Accession:
NP_619825 ↗
Protein ID:
CPXV036_protein
Kingdom:
euk

Quality

72.5 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Pokkesviricetes› Chitovirales› Poxviridae› Orthopoxvirus› Cowpox_virus

TaxID: 10243

Cluster

View cluster (20 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 26-91
PDB
Domain cluster: representative
CATH (23)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4n1kD00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.85 78.0 6.88e-01 100.0% 77.7%
2mpcA00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.85 78.0 6.97e-01 100.0% 81.1%
2dbgA00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.79 71.0 6.13e-01 100.0% 66.0%
1dgnA00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.72 62.0 5.70e-01 100.0% 85.4%
4ikmA02 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.67 58.0 5.23e-01 100.0% 75.3%
7fsfA02 3.30.56.80 Alpha Beta › 2-Layer Sandwich › Phenylalanyl-tRNA Synthetase; Chain B, domain 1 › 0.61 46.0 4.61e-01 95.5% 79.7%
1bjfA02 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.59 49.0 4.56e-01 97.0% 98.9%
6e1kA01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.57 42.0 3.66e-01 81.8% 61.6%
5zzjA02 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.57 42.0 2.75e-01 78.8% 38.5%
4ol8B03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.57 49.0 4.50e-01 100.0% 95.6%
1vfiA00 1.10.246.100 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Vanadium-binding protein 2 0.57 34.0 3.12e-01 77.3% 41.1%
3c7jA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.57 41.0 3.35e-01 81.8% 82.9%
7ml0M01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.56 39.0 3.65e-01 98.5% 58.5%
1aepA00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.56 46.0 3.70e-01 100.0% 94.1%
8sbeA02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.55 41.0 2.98e-01 80.3% 71.7%
6wfqC01 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.55 39.0 3.17e-01 78.8% 82.4%
2i88A00 1.10.490.30 Mainly Alpha › Orthogonal Bundle › Globin-like › Colicin 0.54 46.0 3.50e-01 100.0% 64.0%
2nscA01 3.30.70.1050 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Trigger factor ribosome-binding domain 0.54 38.0 3.64e-01 89.4% 62.8%
4bkxA01 4.10.1240.50 Few Secondary Structures › Irregular › Hormone receptor fold › 0.54 45.0 3.79e-01 100.0% 54.9%
5f64A02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 37.0 3.58e-01 80.3% 65.3%
1ztdA00 1.10.1520.20 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III 0.53 42.0 3.61e-01 98.5% 81.6%
1dcnA03 1.10.40.30 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) 0.51 38.0 3.77e-01 83.3% 90.3%
2ig3A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.51 38.0 3.23e-01 84.8% 65.4%
ECOD (25)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3877650 110.1.1.4 ↗ alpha arrays › DEATH domain › DEATH domain › DEATH domain › PYRIN 0.87 80.0 7.03e-01 100.0% 71.6%
154849 110.1.1.4 ↗ alpha arrays › DEATH domain › DEATH domain › DEATH domain › PYRIN 0.84 77.0 6.70e-01 100.0% 70.1%
3907048 110.1.1.0 ↗ alpha arrays › DEATH domain › DEATH domain › DEATH domain 0.84 76.0 7.10e-01 100.0% 85.0%
4059857 110.1.1.4 ↗ alpha arrays › DEATH domain › DEATH domain › DEATH domain › PYRIN 0.83 76.0 6.44e-01 100.0% 64.8%
3535889 110.1.1.4 ↗ alpha arrays › DEATH domain › DEATH domain › DEATH domain › PYRIN 0.79 69.0 6.23e-01 97.0% 75.6%
4045754 110.1.1.18 ↗ alpha arrays › DEATH domain › DEATH domain › DEATH domain › Death_Lrrd1 0.71 62.0 5.35e-01 100.0% 73.3%
3724166 130.1.1.0 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif 0.66 53.0 5.34e-01 97.0% 89.2%
3754438 108.1.1.0 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand 0.66 52.0 4.30e-01 89.4% 52.8%
3399447 110.1.1.0 ↗ alpha arrays › DEATH domain › DEATH domain › DEATH domain 0.66 56.0 5.44e-01 100.0% 94.7%
4929546 6049.1.1.0 ↗ alpha bundles › PH0832-like › PH0832-like › PH0832-like 0.66 48.0 4.72e-01 78.8% 98.6%
3277330 210.1.2.0 ↗ a+b four layers › Ntn/PP2C › Ntn › Penicillin acylase, catalytic domain 0.65 52.0 5.17e-01 100.0% 84.3%
3882948 110.1.1.2 ↗ alpha arrays › DEATH domain › DEATH domain › DEATH domain › CARD 0.65 54.0 5.11e-01 100.0% 85.9%
3734131 130.1.1.1 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › SAP 0.64 52.0 5.28e-01 97.0% 96.9%
3368018 130.1.1.0 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif 0.63 49.0 4.89e-01 100.0% 85.7%
3191285 130.1.1.16 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › Ish1 0.62 54.0 5.37e-01 100.0% 100.0%
3838265 152.1.2.1 ↗ alpha arrays › RPB6/omega subunit-like › RPB6/omega subunit-like › RNA polymerase omega subunit › RNA_pol_Rpb6 0.58 45.0 4.53e-01 100.0% 84.1%
4129021 2006.1.1.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase 0.56 48.0 3.36e-01 97.0% 27.8%
4142511 2.9.1.1 ↗ beta barrels › OB-fold › RNB domain-like › RNB domain-like › RNB 0.56 48.0 3.00e-01 100.0% 32.2%
4015590 108.1.1.0 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand 0.55 42.0 3.91e-01 86.4% 94.4%
3590150 601.7.1.20 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › Abi_C 0.54 40.0 3.29e-01 81.8% 80.7%
4949396 606.1.1.0 ↗ alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain 0.54 39.0 3.60e-01 78.8% 60.0%
5020814 3290.1.1.0 ↗ alpha complex topology › Cytosolic helical domain in ferrous iron transport protein B › Cytosolic helical domain in ferrous iron transport protein B › Cytosolic helical domain in ferrous iron transport protein B 0.53 39.0 3.63e-01 81.8% 63.3%
3941309 109.8.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Arp2/3 complex 16 KDa subunit ARPC5 › Arp2/3 complex 16 KDa subunit ARPC5 › P16-Arc 0.53 39.0 3.02e-01 78.8% 52.7%
4934893 4271.1.1.3 ↗ alpha complex topology › PriB N-terminal domain-like › PriB N-terminal domain-like › PriB N-terminal domain-like › DNA_primase_lrg_N 0.53 39.0 2.81e-01 81.8% 40.5%
4004317 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.50 33.0 3.15e-01 84.8% 56.2%
D2 high residues 111-230
PDB
Domain cluster: rep: Bcl-2-like_protein__YP_010377017__Monkeypox_virus__10244__D94-213
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF06227.18 best Poxv_Bcl-2-like 70.9 1.50e-19 94.2% 83.3%