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CPXV060_protein

Euk-Vir

Cowpox_virus

CPXV060_protein__NP_619847__Cowpox_virus__10243

Identity

Accession:
NP_619847 ↗
Protein ID:
CPXV060_protein
Kingdom:
euk

Quality

71.0 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1-66
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03337.20 best Pox_F12L 43.4 2.00e-11 93.9% 9.7%
D2 high residues 82-195
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03337.20 best Pox_F12L 170.1 9.10e-50 100.0% 17.5%
D3 medium residues 196-217_389-421
PDB
Domain cluster: representative
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1e6vA02 3.30.70.470 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 45.0 3.16e-01 76.4% 54.9%
3v5nB02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.62 44.0 3.00e-01 74.5% 88.0%
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3738672 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.62 45.0 3.82e-01 76.4% 68.9%
D4 medium residues 218-320
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03337.20 best Pox_F12L 147.5 6.40e-43 100.0% 15.7%
CATH (22)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2py5A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.71 65.0 5.28e-01 98.1% 63.0%
2dulA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.64 43.0 3.01e-01 99.0% 22.7%
3khyA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.62 56.0 4.53e-01 100.0% 91.2%
5ddtA00 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.61 43.0 3.37e-01 99.0% 33.2%
3vpzA02 3.40.367.20 Alpha Beta › 3-Layer(aba) Sandwich › Hexokinase; domain 1 › 0.60 54.0 4.34e-01 100.0% 86.5%
8in8C01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.56 50.0 3.76e-01 100.0% 43.5%
2hb5A00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.56 49.0 4.42e-01 100.0% 72.7%
4wp6A00 3.80.10.10 Alpha Beta › Alpha-Beta Horseshoe › Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) › Ribonuclease Inhibitor 0.56 37.0 3.33e-01 98.1% 46.4%
1sazA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.55 50.0 4.03e-01 100.0% 78.7%
1asuA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.55 46.0 4.03e-01 100.0% 59.3%
4i6kA00 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.54 41.0 3.03e-01 98.1% 30.7%
3f2kB00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.54 42.0 3.59e-01 100.0% 48.1%
2a1fC00 3.40.1160.10 Alpha Beta › 3-Layer(aba) Sandwich › Carbamate kinase › Acetylglutamate kinase-like 0.54 48.0 3.70e-01 99.0% 53.2%
4v1xA02 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.53 43.0 3.00e-01 98.1% 25.8%
3g5jA00 3.40.250.10 Alpha Beta › 3-Layer(aba) Sandwich › Oxidized Rhodanese; domain 1 › Rhodanese-like domain 0.53 48.0 4.42e-01 100.0% 81.5%
2nlyA00 3.20.20.370 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycoside hydrolase/deacetylase 0.52 44.0 3.54e-01 100.0% 45.4%
4m9rB00 3.40.50.1460 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.52 45.0 3.63e-01 100.0% 53.4%
3ed4C01 3.40.720.10 Alpha Beta › 3-Layer(aba) Sandwich › Alkaline Phosphatase, subunit A › Alkaline Phosphatase, subunit A 0.51 44.0 3.10e-01 100.0% 71.9%
2p62A01 3.40.50.10620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › PH0156-like domains 0.51 45.0 4.07e-01 100.0% 90.5%
2ac4A02 3.40.50.1400 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.51 45.0 4.10e-01 100.0% 83.1%
6ia6A01 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.51 43.0 3.27e-01 96.1% 45.7%
3uueA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.51 45.0 3.30e-01 99.0% 38.4%
ECOD (54)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5035328 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.73 67.0 5.06e-01 100.0% 53.2%
4290521 2484.1.1.91 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Exu_RNase_H_like 0.72 67.0 4.88e-01 100.0% 52.5%
3515806 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.71 56.0 5.12e-01 100.0% 63.7%
3937660 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.68 57.0 4.22e-01 99.0% 35.1%
3936953 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.68 58.0 4.12e-01 98.1% 31.8%
3922908 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.66 55.0 4.25e-01 97.1% 40.4%
4255201 2484.1.1.7 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Ribosomal_S11 0.64 53.0 5.24e-01 98.1% 84.5%
4425543 2484.1.1.38 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › eRF1_2 0.63 54.0 5.03e-01 100.0% 76.0%
3628252 2484.1.1.50 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Dimer_Tnp_hAT 0.61 43.0 2.96e-01 98.1% 20.5%
3487266 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.61 55.0 4.25e-01 100.0% 46.7%
3485158 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.60 55.0 4.25e-01 100.0% 46.7%
4968312 2484.1.1.66 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_3 0.60 55.0 4.31e-01 100.0% 57.0%
3924148 2484.1.1.9 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve 0.60 46.0 3.99e-01 100.0% 51.5%
4423612 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.60 55.0 4.39e-01 100.0% 72.0%
3741346 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.60 54.0 4.30e-01 98.1% 51.5%
3860029 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.60 55.0 4.20e-01 100.0% 46.7%
3925663 2484.1.1.9 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve 0.60 46.0 3.90e-01 100.0% 48.6%
3786043 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.60 55.0 4.22e-01 100.0% 66.1%
3780327 2484.1.1.168 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › EloA-BP1 0.60 54.0 4.25e-01 100.0% 72.1%
None 0.60 54.0 4.25e-01 100.0% 72.1%
3924869 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.60 46.0 3.87e-01 98.1% 49.4%
3571354 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.59 54.0 4.17e-01 100.0% 46.7%
4278305 2484.1.1.40 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvX 0.59 49.0 4.45e-01 98.1% 66.7%
3916593 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.59 54.0 4.18e-01 100.0% 65.9%
3219941 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.59 54.0 4.23e-01 100.0% 67.1%
3493529 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.59 54.0 4.14e-01 100.0% 72.4%
3937782 2484.1.1.9 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve 0.59 45.0 3.90e-01 100.0% 51.5%
5036730 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.59 53.0 5.04e-01 100.0% 97.5%
3997241 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.59 53.0 4.85e-01 98.1% 77.4%
3238194 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.59 54.0 4.16e-01 100.0% 69.9%
3935131 2484.1.1.9 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve 0.59 45.0 3.91e-01 100.0% 51.5%
4150748 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.58 46.0 3.96e-01 100.0% 53.8%
3172729 2484.1.1.13 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T 0.58 52.0 4.16e-01 99.0% 52.2%
4017507 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.58 51.0 4.35e-01 100.0% 72.6%
3939670 2484.1.1.9 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve 0.58 46.0 3.88e-01 100.0% 50.9%
3939024 2484.1.1.9 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve 0.57 47.0 3.68e-01 100.0% 41.4%
3939083 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.57 44.0 3.77e-01 100.0% 50.0%
3937850 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.57 45.0 3.85e-01 100.0% 51.8%
3551612 2004.1.1.100 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NTPase_1 0.56 49.0 4.06e-01 98.1% 59.5%
4161288 2484.1.1.174 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › UvrC_RNaseH 0.56 44.0 4.05e-01 96.1% 64.4%
4531223 2484.1.1.55 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › UvrC_RNaseH_dom 0.56 49.0 4.00e-01 97.1% 56.9%
4162179 2484.1.1.25 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvC 0.56 50.0 4.34e-01 98.1% 64.5%
3605420 2484.1.1.26 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Piwi 0.56 50.0 3.80e-01 100.0% 76.4%
3930504 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.56 44.0 3.80e-01 100.0% 53.3%
3733618 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.55 49.0 4.02e-01 100.0% 88.7%
3588043 2010.1.1.0 a/b three-layered sandwiches › EDD domain › EDD domain › EDD domain 0.55 43.0 4.10e-01 98.1% 70.4%
4631411 2484.1.1.25 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvC 0.55 49.0 4.26e-01 100.0% 64.6%
3405383 2005.1.1.36 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › SLC12 0.55 50.0 3.91e-01 100.0% 91.6%
3584031 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.54 41.0 4.11e-01 100.0% 78.2%
4986643 2484.1.1.148 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_5 0.54 47.0 3.32e-01 99.0% 34.8%
4436233 207.11.1.1 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Urease accessory protein ureH › Urease accessory protein ureH › UreD 0.52 44.0 3.32e-01 96.1% 57.8%
164102 2003.6.1.1 a/b three-layered sandwiches › Rossmann-like › Ribokinase-like › Ribokinase-like › PfkB 0.52 46.0 3.27e-01 99.0% 51.9%
3976338 2004.1.1.308 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_21 0.50 44.0 3.08e-01 100.0% 67.8%
3261120 2003.1.4.5 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › SIR2 0.50 43.0 3.26e-01 100.0% 70.5%
D5 medium residues 321-388
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03337.20 best Pox_F12L 72.1 4.30e-20 100.0% 10.5%
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3666591 2484.1.1.36 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_2 0.79 70.0 4.73e-01 100.0% 28.0%
3316523 2484.1.1.36 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_2 0.76 68.0 4.62e-01 100.0% 28.6%
D6 medium residues 434-539
PDB