←Back to structures
CPXV115_protein
Euk-VirCowpox_virus
CPXV115_protein__NP_619900__Cowpox_virus__10243
Identity
- Accession:
- NP_619900 ↗
- Protein ID:
- CPXV115_protein
- Kingdom:
- euk
Quality
90.8
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Orthopoxvirus›
Cowpox_virus
TaxID: 10243
Cluster
View cluster (42 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 3-74
Domain cluster:
rep: hypothetical_protein_OLNG_00081__YP_007674723__Ostreococcus_lucimarinus_virus_OlV5__754064__D2-65
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF09266.17 best | VirDNA-topo-I_N | 101.1 | 4.20e-29 | 80.6% | 100.0% |
CATH (15)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1vccA00 | 3.30.66.10 | Alpha Beta › 2-Layer Sandwich › Viral Topoisomerase I › DNA topoisomerase I domain | 0.99 | 95.0 | 9.30e-01 | 100.0% | 93.5% |
| 2f4qA01 | 3.30.66.10 | Alpha Beta › 2-Layer Sandwich › Viral Topoisomerase I › DNA topoisomerase I domain | 0.80 | 59.0 | 5.99e-01 | 100.0% | 77.8% |
| 2a5hA03 | 6.20.120.40 | Special › Other non-globular › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › | 0.65 | 29.0 | 3.15e-01 | 93.1% | 46.8% |
| 4py5A01 | 3.30.310.10 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › TATA-Binding Protein | 0.62 | 33.0 | 3.33e-01 | 98.6% | 48.6% |
| 2pt7C01 | 3.30.450.90 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › | 0.60 | 36.0 | 3.20e-01 | 72.2% | 40.6% |
| 2xklA00 | 2.40.128.20 | Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain | 0.58 | 43.0 | 3.36e-01 | 100.0% | 37.6% |
| 2i87B02 | 3.30.470.20 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain | 0.57 | 44.0 | 3.53e-01 | 86.1% | 50.3% |
| 1yr1A00 | 3.40.50.10960 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.56 | 46.0 | 3.99e-01 | 93.1% | 78.2% |
| 4bzyA02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.56 | 38.0 | 3.32e-01 | 70.8% | 83.2% |
| 6j8yA00 | 3.70.10.10 | Alpha Beta › Box › Proliferating Cell Nuclear Antigen › | 0.56 | 48.0 | 3.39e-01 | 100.0% | 45.1% |
| 4ld1A00 | 2.60.450.20 | Mainly Beta › Sandwich › lipopolysaccharide transport protein A fold › | 0.54 | 36.0 | 2.82e-01 | 94.4% | 31.2% |
| 1fgyA00 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.53 | 41.0 | 3.45e-01 | 84.7% | 77.0% |
| 5kiqA02 | 3.10.20.890 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › | 0.53 | 35.0 | 3.52e-01 | 73.6% | 68.1% |
| 3a0oA03 | 2.70.98.70 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › | 0.53 | 41.0 | 2.79e-01 | 86.1% | 83.6% |
| 2fsjA01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.51 | 41.0 | 3.19e-01 | 93.1% | 62.8% |
ECOD (21)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 138328 | 818.1.1.1 ↗ | a+b two layers › DNA topoisomerase I domain › DNA topoisomerase I domain › DNA topoisomerase I domain › VirDNA-topo-I_N | 1.00 | 97.0 | 9.38e-01 | 100.0% | 92.3% |
| 1176176 | 818.1.1.2 ↗ | a+b two layers › DNA topoisomerase I domain › DNA topoisomerase I domain › DNA topoisomerase I domain › Top1B_N_bact | 0.80 | 59.0 | 6.20e-01 | 100.0% | 84.8% |
| 3973165 | 818.1.1.0 ↗ | a+b two layers › DNA topoisomerase I domain › DNA topoisomerase I domain › DNA topoisomerase I domain | 0.75 | 65.0 | 6.33e-01 | 100.0% | 86.3% |
| 3289062 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.63 | 37.0 | 3.50e-01 | 100.0% | 46.7% |
| 4424497 | 11.1.1.335 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › GlgB_N | 0.60 | 41.0 | 3.76e-01 | 72.2% | 69.5% |
| 3742632 | 5.1.4.16 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › CPSF_A | 0.59 | 46.0 | 3.08e-01 | 84.7% | 94.1% |
| 4946484 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.59 | 40.0 | 3.13e-01 | 70.8% | 86.7% |
| 3994170 | 5.1.4.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed | 0.58 | 44.0 | 3.21e-01 | 81.9% | 80.9% |
| 5072152 | 325.1.7.12 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › ATP-synt_ab_Xtn | 0.56 | 46.0 | 4.26e-01 | 97.2% | 72.2% |
| 5048875 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.56 | 46.0 | 3.69e-01 | 93.1% | 53.3% |
| 3193261 | 5.1.4.16 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › CPSF_A | 0.55 | 49.0 | 3.10e-01 | 100.0% | 97.0% |
| 2131399 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.55 | 45.0 | 2.83e-01 | 98.6% | 15.6% |
| 3991841 | 389.1.2.1 ↗ | few secondary structure elements › EGF-like › EGF-related › Complement control module/SCR domain › Sushi | 0.55 | 35.0 | 3.70e-01 | 98.6% | 72.3% |
| 3987186 | 321.1.1.7 ↗ | a+b two layers › Glutamine synthetase-like › Glutamine synthetase/guanido kinase › Glutamine synthetase/guanido kinase › GCS2 | 0.53 | 44.0 | 2.79e-01 | 95.8% | 36.7% |
| 3703650 | 79.1.1.0 ↗ | beta duplicates or obligate multimers › Phage tail fiber protein trimerization domain › Phage tail fiber protein trimerization domain › Phage tail fiber protein trimerization domain | 0.53 | 36.0 | 3.65e-01 | 93.1% | 69.3% |
| 4018320 | 5.1.8.3 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › putative conserved lipoprotein NT01CX_1156 › WD40 | 0.53 | 39.0 | 2.95e-01 | 93.1% | 31.1% |
| 3575278 | 5.1.5.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › WD40 | 0.52 | 44.0 | 3.46e-01 | 94.4% | 71.6% |
| 3900659 | 209.1.1.1 ↗ | a+b complex topology › C-type lectin-like › C-type lectin-like › C-type lectin-like › Lectin_C | 0.52 | 37.0 | 3.17e-01 | 91.7% | 43.1% |
| 3469876 | 2003.1.2.24 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Pyr_redox_2 | 0.52 | 43.0 | 2.76e-01 | 93.1% | 33.7% |
| 3939634 | 2.6.1.0 ↗ | beta barrels › OB-fold › Staphylococcal nuclease › Staphylococcal nuclease | 0.52 | 45.0 | 3.89e-01 | 100.0% | 87.8% |
| 3254795 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.51 | 40.0 | 3.21e-01 | 86.1% | 54.0% |
D2
high
residues 108-214
Domain cluster:
rep: S16_GE16_scaffold_10741_prodigal-single.1__X__X__00162__D901-1023
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01028.26 best | Topoisom_I | 57.5 | 1.90e-15 | 100.0% | 46.1% |
D3
high
residues 219-313
Domain cluster:
rep: DNA_topoisomerase_type_I__YP_005296281__Cotia_virus_SPAn232__930275__D223-313