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CPXV128_protein

Euk-Vir

Cowpox_virus

CPXV128_protein__NP_619912__Cowpox_virus__10243

Identity

Accession:
NP_619912 ↗
Protein ID:
CPXV128_protein
Kingdom:
euk

Quality

84.6 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Pokkesviricetes› Chitovirales› Poxviridae› Orthopoxvirus› Cowpox_virus

TaxID: 10243

Cluster

View cluster (106 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 568-630
PDB
Domain cluster: rep: nucleoside_triphosphatase_I__YP_009329721__BeAn_58058_virus__67082__D316-368
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF08469.16 best NPHI_C 87.1 1.70e-24 100.0% 41.9%
D2 medium residues 109-182
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00176.30 best SNF2-rel_dom 36.9 3.20e-09 100.0% 22.2%
CATH (32)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1o5zA02 3.90.190.20 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain 0.69 50.0 4.11e-01 100.0% 41.6%
5dnyA02 3.30.160.600 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.67 46.0 4.99e-01 100.0% 91.4%
2x5oA03 3.90.190.20 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain 0.61 43.0 3.59e-01 100.0% 40.7%
3ef6A02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.60 40.0 3.49e-01 100.0% 42.5%
8alzB05 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.59 50.0 3.77e-01 100.0% 55.6%
2b3tA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.59 39.0 2.95e-01 91.9% 26.0%
2zw9B01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.58 45.0 2.91e-01 91.9% 18.2%
3pukA01 3.40.50.2060 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Sec1/Munc18 (SM) protein, domain 1 0.58 40.0 3.38e-01 87.8% 41.9%
2r9zA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.58 42.0 3.67e-01 100.0% 49.2%
4beqA02 3.20.20.10 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase 0.56 48.0 3.53e-01 100.0% 48.4%
7w6bA01 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.56 47.0 3.29e-01 100.0% 62.4%
3milB00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.55 48.0 3.41e-01 100.0% 68.1%
3p94A00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.55 47.0 3.52e-01 100.0% 66.2%
7mi0A01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.55 41.0 3.23e-01 100.0% 33.9%
1p91B00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 38.0 2.70e-01 93.2% 21.3%
1dljA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 38.0 3.42e-01 85.1% 50.9%
2qkbA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.54 45.0 3.76e-01 100.0% 78.3%
3l7iA02 3.40.50.12580 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › CDP-glycerol glycerophosphotransferase, C-terminal domain 0.54 48.0 3.62e-01 100.0% 69.4%
3r89A00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.54 47.0 3.22e-01 100.0% 27.0%
3rssA01 3.40.50.10260 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › YjeF N-terminal domain 0.53 46.0 3.40e-01 100.0% 37.0%
3f9tA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.53 45.0 3.20e-01 100.0% 44.4%
3n8hA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.53 46.0 3.55e-01 98.6% 83.0%
4gicA01 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.53 47.0 3.79e-01 100.0% 84.0%
2hhgA00 3.40.250.10 Alpha Beta › 3-Layer(aba) Sandwich › Oxidized Rhodanese; domain 1 › Rhodanese-like domain 0.52 39.0 3.31e-01 100.0% 46.2%
4rkrD02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 38.0 3.18e-01 87.8% 41.7%
7a8rA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 41.0 3.17e-01 93.2% 82.4%
6qv4A04 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 43.0 3.32e-01 100.0% 63.5%
6cv6D00 3.40.50.9100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Dehydroquinase, class II 0.52 45.0 3.66e-01 100.0% 85.4%
1kwgA02 3.40.50.880 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain 0.52 44.0 3.31e-01 100.0% 84.0%
6b4kB02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 44.0 3.46e-01 100.0% 48.8%
6i1dA02 3.40.50.10890 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.50 42.0 3.28e-01 100.0% 43.9%
7r7jA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.50 42.0 3.24e-01 100.0% 38.7%
ECOD (25)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4801462 2004.1.1.23 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom 0.91 87.0 5.90e-01 100.0% 32.5%
3177789 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.60 51.0 4.01e-01 100.0% 71.8%
4133184 323.1.1.3 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.59 42.0 3.38e-01 100.0% 36.1%
4965650 7592.1.1.0 ↗ a/b three-layered sandwiches › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains 0.59 50.0 4.14e-01 100.0% 52.1%
3782029 2003.1.4.5 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › SIR2 0.58 51.0 3.46e-01 100.0% 39.3%
3940020 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.58 48.0 4.11e-01 97.3% 82.3%
3479894 7585.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins 0.57 41.0 3.43e-01 90.5% 43.1%
3439529 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.57 47.0 3.80e-01 100.0% 74.5%
4999435 2007.1.1.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Class I glutamine amidotransferase-like 0.56 47.0 3.55e-01 100.0% 81.4%
3599830 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.55 48.0 3.38e-01 100.0% 61.2%
4535809 7573.1.1.1 ↗ a/b three-layered sandwiches › PRTase-like › PRTase-like › PRTase-like › Pribosyltran 0.55 37.0 2.94e-01 91.9% 31.2%
4556621 7541.1.1.1 ↗ a/b three-layered sandwiches › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › MoCF_biosynth 0.54 47.0 3.71e-01 100.0% 47.9%
3788549 2007.2.3.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II 0.54 46.0 3.47e-01 100.0% 42.9%
4585333 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.54 47.0 4.23e-01 100.0% 78.1%
4489917 7512.1.1.46 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_11 0.54 44.0 3.36e-01 100.0% 37.3%
3601226 2004.1.1.24 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom,Helicase_C 0.54 47.0 2.77e-01 100.0% 26.7%
4021650 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.53 39.0 3.07e-01 78.4% 75.8%
4414072 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.53 46.0 3.55e-01 100.0% 46.9%
1174411 2005.1.1.0 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.52 44.0 3.46e-01 98.6% 45.7%
5013586 2006.1.4.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › PIN 0.52 43.0 3.65e-01 100.0% 55.9%
3603635 2007.13.1.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Rossmann-like domains in magnesium chelatase catalytic subunit › Rossmann-like domains in magnesium chelatase catalytic subunit › CobN-Mg_chel 0.52 45.0 3.25e-01 100.0% 40.9%
4603400 7512.1.1.46 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_11 0.52 43.0 3.17e-01 100.0% 32.6%
5064692 2004.1.1.210 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ERCC3_RAD25_C 0.52 44.0 3.41e-01 100.0% 54.1%
3592413 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.52 43.0 3.38e-01 100.0% 48.1%
3176793 2007.2.5.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Rhodanese/Cell cycle control phosphatase › Rhodanese 0.50 43.0 3.61e-01 100.0% 75.0%
D3 medium residues 213-235_521-564
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF08469.16 best NPHI_C 65.0 1.10e-17 74.6% 29.7%
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3241590 327.11.2.1 ↗ a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1 0.52 36.0 3.37e-01 73.1% 95.3%
D4 medium residues 236-267_363-509
PDB
Domain cluster: rep: IMGVR_UViG_3300026211_000011-3300026211-Ga0208132_10019531__D46-252
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF00271.38 best Helicase_C 48.2 1.60e-12 72.1% 90.0%
PF08469.16 NPHI_C 35.1 1.80e-08 15.1% 18.2%