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CPXV130_protein

Euk-Vir

Cowpox_virus

CPXV130_protein__NP_851588__Cowpox_virus__10243

Identity

Accession:
NP_851588 ↗
Protein ID:
CPXV130_protein
Kingdom:
euk

Quality

72.2 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 11-66
PDB
Domain cluster: representative
CATH (52)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1jadA00 1.20.1230.10 Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain 0.89 82.0 5.21e-01 100.0% 34.7%
8e9gK01 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.87 79.0 6.61e-01 100.0% 61.5%
2fupA00 1.20.58.300 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like 0.83 60.0 4.56e-01 80.4% 33.9%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.82 76.0 5.44e-01 100.0% 38.1%
2fcwA00 1.20.81.10 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain 0.81 65.0 5.24e-01 91.1% 46.2%
6ynwH01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.81 71.0 6.55e-01 100.0% 79.7%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.80 72.0 6.41e-01 100.0% 71.8%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.79 57.0 4.74e-01 78.6% 46.2%
2mpkA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.78 62.0 5.72e-01 94.6% 67.6%
1k04A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.75 64.0 5.26e-01 96.4% 79.8%
3h6pC00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.75 65.0 6.59e-01 98.2% 100.0%
3eslA01 1.20.58.2070 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 55.0 5.04e-01 89.3% 60.0%
4wzxA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.74 53.0 4.85e-01 98.2% 57.3%
3vm9A02 6.10.140.2110 Special › Helix non-globular › Helix Hairpins › 0.74 60.0 6.03e-01 92.9% 94.7%
4q5nA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.73 60.0 4.83e-01 92.9% 47.3%
1b3qA01 1.10.287.560 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Histidine kinase CheA-like, homodimeric domain 0.73 57.0 5.56e-01 91.1% 77.4%
2r9iA00 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.73 64.0 5.91e-01 98.2% 80.3%
3vkgA02 1.20.140.100 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain 0.72 64.0 4.67e-01 98.2% 39.5%
3pltA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.72 64.0 4.27e-01 100.0% 27.6%
3na7A00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.72 63.0 4.13e-01 98.2% 24.1%
4ijjB00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.71 60.0 4.61e-01 98.2% 40.8%
1a36A04 1.10.132.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.71 60.0 4.22e-01 98.2% 30.3%
1lrzA03 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 63.0 6.07e-01 98.2% 91.9%
4a17U01 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.70 60.0 5.40e-01 96.4% 68.8%
1zhcA00 6.10.280.50 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 60.0 5.50e-01 98.2% 86.8%
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 61.0 5.61e-01 98.2% 78.1%
6tkvA01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.70 58.0 5.55e-01 98.2% 85.3%
3lphC00 6.10.140.630 Special › Helix non-globular › Helix Hairpins › 0.69 55.0 5.46e-01 98.2% 84.5%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.69 59.0 5.39e-01 100.0% 76.6%
3hiuD00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.69 55.0 4.08e-01 91.1% 32.9%
1pd3A00 1.10.287.230 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.69 53.0 5.39e-01 89.3% 90.7%
2odmA00 1.10.287.750 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like 0.68 51.0 4.70e-01 91.1% 60.8%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 58.0 5.39e-01 98.2% 74.6%
2lw1A00 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.68 59.0 5.13e-01 98.2% 72.9%
3cjdA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.68 54.0 3.73e-01 85.7% 50.5%
4fppB01 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.67 58.0 5.41e-01 100.0% 84.5%
2e62A01 6.10.140.420 Special › Helix non-globular › Helix Hairpins › 0.66 51.0 5.27e-01 85.7% 92.3%
1hr5A00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.66 50.0 5.31e-01 85.7% 95.8%
2hh7A00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.65 54.0 4.84e-01 100.0% 69.4%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.65 56.0 5.18e-01 100.0% 76.0%
3ltoA02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.65 52.0 4.08e-01 94.6% 39.6%
6qs7C01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.65 53.0 4.02e-01 91.1% 37.9%
7ymiZ01 1.10.287.740 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre 0.65 53.0 5.25e-01 89.3% 86.2%
1dd3A01 1.20.5.710 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Single helix bin 0.65 46.0 4.62e-01 96.4% 75.4%
4q5qA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.63 48.0 4.06e-01 91.1% 46.7%
4e4eA01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.63 51.0 4.80e-01 98.2% 74.6%
1cpyA02 1.10.287.410 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.62 47.0 4.45e-01 96.4% 68.1%
1kfdA02 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.62 52.0 4.87e-01 98.2% 80.3%
1ku9A02 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.61 53.0 5.10e-01 96.4% 84.4%
4hb1A00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.61 44.0 4.91e-01 83.9% 97.7%
1hlvA02 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.60 45.0 4.41e-01 87.5% 75.0%
3iqtA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.59 48.0 3.98e-01 98.2% 91.2%
ECOD (41)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3976071 3826.1.1.0 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) 0.92 85.0 7.09e-01 100.0% 65.6%
2471294 310.2.1.1 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF 0.91 84.0 5.53e-01 100.0% 27.5%
3626992 632.8.1.2 alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › Alpha-2-MRAP_C 0.84 68.0 5.46e-01 91.1% 46.7%
223985 3600.1.1.1 alpha bundles › uncharacterized protein SYNW0670 › uncharacterized protein SYNW0670 › uncharacterized protein SYNW0670 › YlqD 0.82 76.0 5.46e-01 100.0% 38.4%
3971727 5043.2.1.0 extended segments › Sensor proteins transmembrane domains › NarQ transmembrane domain › NarQ transmembrane domain 0.79 59.0 6.02e-01 98.2% 81.8%
4946791 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.78 69.0 6.29e-01 100.0% 74.7%
4961508 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.76 67.0 6.10e-01 98.2% 80.0%
4012407 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.76 63.0 6.19e-01 98.2% 86.7%
3855461 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.76 63.0 5.45e-01 91.1% 67.1%
2323907 212.1.1.24 a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Morc6_S5 0.75 62.0 4.09e-01 91.1% 25.1%
3731062 3826.1.1.0 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) 0.74 66.0 5.74e-01 100.0% 70.6%
3614494 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.74 62.0 4.06e-01 100.0% 21.2%
1203190 192.3.1.1 alpha bundles › Long alpha-hairpin › Fe,Mn superoxide dismutase (SOD), N-terminal domain › Fe,Mn superoxide dismutase (SOD), N-terminal domain › Sod_Fe_N 0.74 61.0 5.15e-01 96.4% 54.8%
3902100 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.74 64.0 5.52e-01 98.2% 62.4%
4964878 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.73 64.0 5.89e-01 100.0% 75.7%
5048188 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.73 65.0 4.63e-01 98.2% 37.5%
3556027 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.73 63.0 5.44e-01 98.2% 62.4%
3174647 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.73 65.0 6.02e-01 98.2% 85.7%
3240117 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.73 63.0 5.42e-01 98.2% 74.4%
3487862 212.1.1.0 a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like 0.72 62.0 4.04e-01 98.2% 22.1%
3491418 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.72 62.0 5.64e-01 98.2% 70.7%
4613072 101.1.2.721 alpha arrays › HTH › HTH › winged helix domain › MarR_2, PF27113 0.72 63.0 4.50e-01 98.2% 35.2%
3684015 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.72 62.0 5.16e-01 98.2% 60.0%
4010395 622.4.1.26 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › HisKA 0.71 61.0 5.64e-01 92.9% 78.6%
3973158 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.71 64.0 5.64e-01 98.2% 72.5%
3982421 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.71 64.0 5.75e-01 98.2% 77.3%
3694629 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.71 63.0 5.58e-01 98.2% 72.5%
3258925 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.71 60.0 5.60e-01 98.2% 75.7%
3596490 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.70 64.0 5.39e-01 100.0% 66.7%
3401938 3602.1.1.14 alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › DUF733 0.70 60.0 5.42e-01 98.2% 70.7%
4942789 4323.1.1.0 alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C 0.70 63.0 4.66e-01 100.0% 66.4%
3315495 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.70 60.0 5.20e-01 98.2% 62.4%
3253483 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.70 61.0 5.69e-01 98.2% 81.4%
4129936 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.70 59.0 5.00e-01 96.4% 60.0%
3973453 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.68 60.0 5.32e-01 100.0% 75.0%
5002089 2004.1.1.144 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD_2 0.67 55.0 3.45e-01 96.4% 16.2%
3214887 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.67 54.0 5.47e-01 98.2% 92.7%
3413114 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.67 54.0 5.15e-01 91.1% 75.4%
3345952 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.66 59.0 5.10e-01 100.0% 68.2%
4784166 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.65 56.0 5.25e-01 98.2% 80.0%
3344575 9.26.1.0 beta barrels › Lipocalins/Streptavidin 0.61 54.0 3.76e-01 100.0% 28.7%