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CPXV198_protein

Euk-Vir

Cowpox_virus

CPXV198_protein__NP_619979__Cowpox_virus__10243

Identity

Accession:: NP_619979 ↗
Protein ID:: CPXV198_protein
Kingdom:: euk

Quality

74.9 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Pokkesviricetes› Chitovirales› Poxviridae› Orthopoxvirus› Cowpox_virus

TaxID: 10243

Cluster

View cluster (8 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 26-91

PDB

D2 high residues 460-557

PDB

Domain cluster: rep: Ankyrin_repeat_protein__YP_009408119__Eptesipox_virus__1329402__D558-647

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF09372.16 best	PRANC	84.4	8.20e-24	94.9%	97.9%

CATH (14)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3hiuD00	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.65	47.0	4.09e-01	75.5%	96.7%
3b0cW00	1.10.20.10	Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A	0.63	42.0	4.74e-01	90.8%	91.8%
3pm0A00	1.10.630.10	Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450	0.60	50.0	3.22e-01	89.8%	52.7%
2vxxA00	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.58	44.0	3.67e-01	80.6%	64.5%
4hteA02	1.20.58.1740	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.57	41.0	3.85e-01	74.5%	66.7%
4cybD00	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.57	44.0	3.64e-01	81.6%	64.9%
4btfA01	1.20.930.20	Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Adaptor protein Cbl, N-terminal domain	0.56	43.0	4.27e-01	79.6%	94.0%
3buxB01	1.20.930.20	Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Adaptor protein Cbl, N-terminal domain	0.56	41.0	3.77e-01	77.6%	88.4%
3zevB00	1.20.1070.10	Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins	0.55	43.0	3.09e-01	85.7%	78.0%
3ha4B00	1.20.58.690	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.55	41.0	3.87e-01	79.6%	65.0%
7zxkC01	1.20.1250.10	Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; ›	0.54	43.0	3.73e-01	85.7%	82.7%
1ad6A00	1.10.472.10	Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like	0.53	47.0	3.77e-01	95.9%	65.9%
1lk3A00	1.20.1250.10	Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; ›	0.53	39.0	3.46e-01	75.5%	90.4%
1aluA00	1.20.1250.10	Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; ›	0.51	38.0	3.26e-01	78.6%	87.9%

ECOD (17)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3722689	148.1.1.12 ↗	alpha arrays › Histone-like › Histone-related › Histone › Bromo_TP	0.64	40.0	3.76e-01	88.8%	50.8%
3249270	5050.1.1.0 ↗	alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter	0.61	44.0	3.39e-01	74.5%	84.0%
3738949	5051.1.1.3 ↗	alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › SSF	0.61	50.0	3.08e-01	89.8%	47.0%
3659606	3361.1.1.5 ↗	alpha bundles › C-terminal Pdr1-activating domain of J-protein Zuo1 › C-terminal Pdr1-activating domain of J-protein Zuo1 › C-terminal Pdr1-activating domain of J-protein Zuo1 › PF28983	0.60	42.0	4.00e-01	72.4%	81.7%
3337919	109.4.1.1146 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_PUB	0.59	45.0	3.48e-01	79.6%	42.4%
3204262	5051.1.1.15 ↗	alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › K_trans	0.57	47.0	3.42e-01	92.9%	85.9%
5030197	601.7.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain	0.56	40.0	3.39e-01	76.5%	98.9%
3588543	1188.1.1.1 ↗	alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter › Zip	0.55	48.0	3.52e-01	98.0%	88.5%
3725163	601.39.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Enhancer of filamentation 1 › Enhancer of filamentation 1	0.54	46.0	3.47e-01	95.9%	39.1%
4011664	192.29.1.0 ↗	alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding)	0.54	44.0	3.41e-01	95.9%	41.0%
5000127	2484.1.1.330 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF460	0.53	46.0	3.82e-01	96.9%	83.3%
4671965	589.1.2.6 ↗	alpha arrays › Triger factor/SurA peptide-binding domain-like › Triger factor/SurA peptide-binding domain-like › TF C-terminus (Pfam 05698) › SurA_N_3	0.52	46.0	3.68e-01	95.9%	84.2%
3919329	148.1.1.0 ↗	alpha arrays › Histone-like › Histone-related › Histone	0.52	38.0	3.63e-01	89.8%	64.3%
1883360	1101.1.1.1 ↗	alpha bundles › Uncharacterized protein LPG2271 › Uncharacterized protein LPG2271 › Uncharacterized protein LPG2271 › DUF5638	0.52	35.0	3.44e-01	95.9%	63.6%
5008952	5061.1.1.1 ↗	alpha complex topology › Preprotein translocase SecY subunit › Preprotein translocase SecY subunit › Preprotein translocase SecY subunit › SecY	0.52	42.0	2.73e-01	87.8%	77.5%
3389719	632.7.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain	0.51	47.0	4.44e-01	100.0%	94.8%
3277476	174.1.1.0 ↗	few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain	0.50	46.0	3.94e-01	100.0%	64.7%

D3 medium residues 128-276

PDB

Domain cluster: rep: MN180249.1__QHJ75400.1__X__00002__D85-208

Pfam (4)

Accession	Name	Score	E-value	Q cov	HMM cov
PF12796.14 best	Ank_2	54.3	2.40e-14	61.7%	91.1%
PF00023.37	Ank	18.0	3.90e-03	26.9%	97.0%
PF00023.37	Ank	35.1	1.50e-08	22.1%	100.0%
PF13606.13	Ank_3	17.4	7.00e-03	20.1%	100.0%

D4 medium residues 277-335

PDB

Domain cluster: representative

CATH (11)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2vkpB00	3.30.710.10	Alpha Beta › 2-Layer Sandwich › Potassium Channel Kv1.1; Chain A › Potassium Channel Kv1.1; Chain A	0.63	46.0	3.89e-01	94.9%	44.0%
4eacC01	3.20.20.150	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Divalent-metal-dependent TIM barrel enzymes	0.61	51.0	3.43e-01	100.0%	63.1%
2vpkA00	3.30.710.10	Alpha Beta › 2-Layer Sandwich › Potassium Channel Kv1.1; Chain A › Potassium Channel Kv1.1; Chain A	0.61	44.0	3.68e-01	91.5%	41.7%
3t5vA00	1.25.40.990	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat ›	0.59	46.0	3.03e-01	89.8%	27.8%
1texA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.58	47.0	3.21e-01	94.9%	73.6%
4h0eA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.57	41.0	3.98e-01	81.4%	85.7%
3mopA00	1.10.533.10	Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas	0.56	38.0	3.23e-01	71.2%	86.7%
3eetA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.55	42.0	4.11e-01	86.4%	87.7%
1t98A01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.53	39.0	3.47e-01	79.7%	79.3%
4ixjA02	3.30.1690.20	Alpha Beta › 2-Layer Sandwich › TcpA-like pilin ›	0.53	36.0	2.79e-01	72.9%	79.6%
1xzpA02	1.20.120.430	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2	0.53	40.0	2.99e-01	84.7%	51.8%

ECOD (12)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3452544	109.3.1.8 ↗	alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_2	0.75	66.0	4.69e-01	100.0%	35.0%
4993561	316.1.1.0 ↗	a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase	0.67	52.0	3.78e-01	88.1%	40.6%
3302202	3745.1.1.1 ↗	alpha bundles › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Na_Ca_ex	0.61	50.0	3.17e-01	94.9%	70.6%
3482935	226.1.1.0 ↗	a+b two layers › POZ domain › POZ domain › POZ domain	0.61	42.0	3.74e-01	86.4%	48.9%
3233112	226.1.1.1 ↗	a+b two layers › POZ domain › POZ domain › POZ domain › BTB	0.59	47.0	3.71e-01	94.9%	40.0%
3701873	191.1.1.0 ↗	alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain	0.57	41.0	3.42e-01	76.3%	70.0%
3277999	5059.1.1.1 ↗	alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA	0.56	43.0	2.93e-01	93.2%	62.1%
3961674	101.1.2.6 ↗	alpha arrays › HTH › HTH › winged helix domain › GntR	0.54	43.0	4.01e-01	89.8%	88.0%
4655422	601.25.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain › MnmE_helical	0.54	40.0	2.99e-01	83.1%	54.1%
3717954	108.1.1.0 ↗	alpha arrays › EF-hand › EF-hand-related › EF-hand	0.52	41.0	3.68e-01	91.5%	87.8%
3811330	2003.1.2.24 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Pyr_redox_2	0.51	43.0	2.71e-01	100.0%	22.2%
5058742	2004.1.1.42 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE	0.50	40.0	2.41e-01	100.0%	29.6%

D5 medium residues 336-444

PDB

Domain cluster: rep: ankyrin_repeat_protein__NP_938269__Yaba_monkey_tumor_virus__38804__D426-549