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CPXV211_protein
Euk-VirCowpox_virus
CPXV211_protein__NP_619992__Cowpox_virus__10243
Identity
- Accession:
- NP_619992 ↗
- Protein ID:
- CPXV211_protein
- Kingdom:
- euk
Quality
84.8
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Orthopoxvirus›
Cowpox_virus
TaxID: 10243
Cluster
View cluster (58 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-126
Domain cluster:
rep: Ankyrin__YP_009143502__Raccoonpox_virus__10256__D1-135
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00023.37 best | Ank | 21.4 | 3.40e-04 | 27.8% | 93.9% |
D2
medium
residues 127-301
Domain cluster:
rep: MN180249.1__QHJ75400.1__X__00002__D85-208
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF13637.13 best | Ank_4 | 23.8 | 6.10e-05 | 25.1% | 76.0% |
D3
medium
residues 302-444
Domain cluster:
rep: hypothetical_protein_VARVgp187__NP_042231__Variola_virus__10255__D321-452
Pfam (3)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF12796.14 best | Ank_2 | 27.4 | 5.60e-06 | 66.4% | 77.8% |
| PF00023.37 | Ank | 25.3 | 1.90e-05 | 23.1% | 93.9% |
| PF13606.13 | Ank_3 | 27.6 | 3.10e-06 | 21.0% | 96.8% |
D4
medium
residues 445-520
Domain cluster:
representative
CATH (21)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1wrdA00 | 1.20.58.160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 48.0 | 4.43e-01 | 77.6% | 81.6% |
| 3ph0C00 | 1.25.40.1040 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.62 | 41.0 | 4.72e-01 | 77.6% | 98.1% |
| 4rngC00 | 1.20.1280.290 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.58 | 44.0 | 4.32e-01 | 82.9% | 89.2% |
| 4dmvA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 43.0 | 4.21e-01 | 81.6% | 77.6% |
| 2p06B00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.57 | 48.0 | 4.67e-01 | 97.4% | 96.6% |
| 2x6hA01 | 1.25.40.70 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Phosphatidylinositol 3-kinase, accessory domain (PIK) | 0.57 | 41.0 | 3.13e-01 | 77.6% | 35.5% |
| 2qgmA03 | 1.20.1440.30 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Biosynthetic Protein domain | 0.56 | 43.0 | 3.82e-01 | 84.2% | 71.6% |
| 1nf1A02 | 1.10.506.10 | Mainly Alpha › Orthogonal Bundle › GTPase Activation - p120GAP; domain 1 › GTPase Activation - p120gap; domain 1 | 0.56 | 41.0 | 3.18e-01 | 77.6% | 66.1% |
| 2gs4A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.54 | 47.0 | 3.80e-01 | 100.0% | 94.9% |
| 2o57A01 | 1.10.287.840 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Mycolic acid cyclopropane synthase domain like | 0.54 | 45.0 | 4.16e-01 | 100.0% | 94.3% |
| 2rbdA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.53 | 46.0 | 3.76e-01 | 98.7% | 94.7% |
| 2chpA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.53 | 47.0 | 3.81e-01 | 100.0% | 98.0% |
| 3e6sA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.53 | 46.0 | 3.71e-01 | 100.0% | 88.1% |
| 2kfdA00 | 1.10.10.440 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › FF domain | 0.53 | 37.0 | 3.94e-01 | 80.3% | 86.2% |
| 1bgcA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.52 | 45.0 | 3.63e-01 | 98.7% | 79.7% |
| 3ihuA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.52 | 40.0 | 3.32e-01 | 82.9% | 61.2% |
| 1nfvA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.52 | 45.0 | 3.54e-01 | 100.0% | 81.1% |
| 2l6jA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.52 | 39.0 | 3.51e-01 | 82.9% | 79.3% |
| 4mk3A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.51 | 36.0 | 3.26e-01 | 76.3% | 57.4% |
| 2kiwA01 | 1.10.150.130 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain | 0.51 | 43.0 | 4.13e-01 | 96.1% | 82.6% |
| 4mhlA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.50 | 43.0 | 3.48e-01 | 100.0% | 77.6% |
ECOD (17)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3912101 | 604.6.1.1 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT | 0.70 | 49.0 | 4.51e-01 | 73.7% | 78.0% |
| 4999760 | 109.4.1.207 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_2 | 0.69 | 48.0 | 3.79e-01 | 73.7% | 51.0% |
| 3924442 | 604.6.1.1 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT | 0.69 | 48.0 | 4.25e-01 | 73.7% | 70.9% |
| 3593236 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.64 | 45.0 | 4.02e-01 | 73.7% | 70.0% |
| 3601623 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.62 | 46.0 | 4.35e-01 | 77.6% | 80.0% |
| 5039404 | 604.2.1.0 ↗ | alpha bundles › Spectrin repeat-like › Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain › Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain | 0.62 | 46.0 | 4.67e-01 | 78.9% | 90.7% |
| 4963427 | 604.2.1.0 ↗ | alpha bundles › Spectrin repeat-like › Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain › Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain | 0.62 | 47.0 | 4.38e-01 | 81.6% | 74.7% |
| 3710520 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.60 | 45.0 | 3.69e-01 | 81.6% | 95.3% |
| 3603265 | 2004.1.1.712 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF87, HerA_C, TrwB_AAD_bind | 0.58 | 45.0 | 2.93e-01 | 100.0% | 17.1% |
| 3682397 | 604.12.1.65 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT_ATG1 | 0.58 | 41.0 | 3.84e-01 | 76.3% | 73.5% |
| 3187918 | 3324.1.1.0 ↗ | extended segments › Helical arch in Ski2-like helicases › Helical arch in Ski2-like helicases › Helical arch in Ski2-like helicases | 0.57 | 45.0 | 3.98e-01 | 88.2% | 86.1% |
| 5008490 | 159.1.1.1 ↗ | alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › Hypothetical protein AF_0060 › MazG | 0.56 | 43.0 | 4.14e-01 | 85.5% | 89.8% |
| 5077884 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.55 | 41.0 | 4.10e-01 | 81.6% | 96.2% |
| 3881724 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.54 | 40.0 | 3.52e-01 | 78.9% | 85.2% |
| 3715769 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.53 | 44.0 | 3.14e-01 | 96.1% | 60.4% |
| 3412589 | 603.1.1.136 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › HB_ELP1 | 0.51 | 44.0 | 3.31e-01 | 94.7% | 91.1% |
| 3396169 | 633.12.1.3 ↗ | alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › PIEZO | 0.50 | 37.0 | 3.11e-01 | 80.3% | 48.6% |
D5
medium
residues 521-574
Domain cluster:
rep: HSPV194__ABH08307__Horsepox_virus__397342__D518-574
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF09372.16 best | PRANC | 38.0 | 2.50e-09 | 90.7% | 48.4% |