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CPXV223_protein
Euk-VirCowpox_virus
CPXV223_protein__NP_620003__Cowpox_virus__10243
Identity
- Accession:
- NP_620003 ↗
- Protein ID:
- CPXV223_protein
- Kingdom:
- euk
Quality
82.0
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Orthopoxvirus›
Cowpox_virus
TaxID: 10243
Cluster
View cluster (23 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 570-671
Domain cluster:
rep: Ankyrin_repeat_protein_-2-__YP_010377009__Monkeypox_virus__10244__D574-659
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF09372.16 best | PRANC | 49.1 | 8.10e-13 | 81.4% | 87.6% |
CATH (13)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4e4eA01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.71 | 35.0 | 4.19e-01 | 89.2% | 69.0% |
| 3qhbA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.66 | 47.0 | 3.93e-01 | 74.5% | 87.2% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.65 | 33.0 | 4.05e-01 | 93.1% | 74.6% |
| 1lkoA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.65 | 49.0 | 4.37e-01 | 80.4% | 100.0% |
| 5hyhA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.61 | 51.0 | 3.77e-01 | 93.1% | 72.5% |
| 1i6zA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.59 | 44.0 | 4.01e-01 | 79.4% | 83.7% |
| 2ijeS00 | 1.10.840.10 | Mainly Alpha › Orthogonal Bundle › Son of Sevenless (SoS) protein; Chain S, domain 2 › Ras guanine-nucleotide exchange factors catalytic domain | 0.57 | 50.0 | 3.86e-01 | 97.1% | 78.9% |
| 6fahC01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.56 | 44.0 | 4.20e-01 | 85.3% | 94.1% |
| 3khkB01 | 1.20.1260.30 | Mainly Alpha › Up-down Bundle › Ferritin › N6 adenine-specific DNA methyltransferase, N-terminal domain | 0.55 | 39.0 | 3.29e-01 | 97.1% | 46.5% |
| 4gycA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.54 | 45.0 | 3.52e-01 | 91.2% | 50.9% |
| 4iu9B01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.53 | 45.0 | 3.53e-01 | 93.1% | 90.2% |
| 2e9xA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 40.0 | 3.70e-01 | 83.3% | 79.7% |
| 2g5cB02 | 1.10.3660.10 | Mainly Alpha › Orthogonal Bundle › 6-phosphogluconate dehydrogenase C-terminal fold › 6-phosphogluconate dehydrogenase C-terminal like domain | 0.51 | 40.0 | 3.95e-01 | 85.3% | 95.5% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3934153 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.65 | 49.0 | 5.10e-01 | 79.4% | 98.9% |
| 3521423 | 5059.1.1.3 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › TPT | 0.62 | 48.0 | 3.42e-01 | 82.4% | 57.0% |
| 3271907 | 70.3.1.1 ↗ | beta barrels › beta-clip › SET domain-like › SET domain-like › SET | 0.60 | 41.0 | 2.86e-01 | 70.6% | 43.0% |
| 3583711 | 5067.1.1.3 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Patched | 0.58 | 37.0 | 3.35e-01 | 75.5% | 47.4% |
| 3859519 | 5001.1.1.43 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › V1R | 0.58 | 51.0 | 3.60e-01 | 94.1% | 79.9% |
| 4986068 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.58 | 49.0 | 3.97e-01 | 94.1% | 89.5% |
| 3201430 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.57 | 41.0 | 4.09e-01 | 75.5% | 98.2% |
| 3610921 | 604.5.1.36 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › UPF0220 | 0.56 | 42.0 | 3.85e-01 | 77.5% | 77.7% |
| 3693146 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.56 | 39.0 | 3.20e-01 | 71.6% | 72.4% |
| 4069762 | 195.1.1.1 ↗ | alpha complex topology › NusB-like › NusB-like › NusB-like › NusB | 0.55 | 42.0 | 3.64e-01 | 82.4% | 75.8% |
| 3489137 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.55 | 44.0 | 3.58e-01 | 88.2% | 86.3% |
| 3181568 | 109.4.1.681 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans_2 | 0.55 | 49.0 | 3.24e-01 | 100.0% | 92.0% |
| 4988860 | 1076.1.1.0 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related | 0.54 | 43.0 | 3.63e-01 | 85.3% | 76.0% |
| 3414371 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.52 | 42.0 | 3.44e-01 | 88.2% | 86.2% |
| 5016149 | 5045.1.1.3 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › V_ATPase_I | 0.52 | 39.0 | 2.78e-01 | 80.4% | 44.8% |
| 3304359 | 304.48.1.70 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Intron_maturas2 | 0.51 | 43.0 | 2.73e-01 | 90.2% | 30.1% |
| 4002396 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.51 | 39.0 | 3.28e-01 | 83.3% | 59.5% |
| 3697051 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.50 | 42.0 | 3.53e-01 | 94.1% | 71.1% |
D2
medium
residues 1-149
Domain cluster:
rep: Ankyrin_repeat-containing_protein__YP_009143317__Raccoonpox_virus__10256__D1-111
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00023.37 best | Ank | 18.7 | 2.40e-03 | 24.2% | 97.0% |
D3
medium
residues 150-306
Domain cluster:
rep: Ankyrin_repeat-containing_protein__YP_009143317__Raccoonpox_virus__10256__D1-111
D4
medium
residues 307-427
Domain cluster:
rep: Ankyrin_repeat-containing_protein__YP_009143317__Raccoonpox_virus__10256__D306-408
D5
medium
residues 428-569
Domain cluster:
rep: ankyrin_repeat_protein__NP_938269__Yaba_monkey_tumor_virus__38804__D426-549
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00023.37 best | Ank | 17.2 | 7.30e-03 | 23.2% | 87.9% |