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CPXV225_protein

Euk-Vir

Cowpox_virus

CPXV225_protein__NP_620004__Cowpox_virus__10243

Identity

Accession:: NP_620004 ↗
Protein ID:: CPXV225_protein
Kingdom:: euk

Quality

80.0 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Pokkesviricetes› Chitovirales› Poxviridae› Orthopoxvirus› Cowpox_virus

TaxID: 10243

Cluster

View cluster (58 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 22-162

PDB

Domain cluster: rep: MN180249.1__QHJ75400.1__X__00002__D85-208

D2 medium residues 163-302

PDB

Domain cluster: rep: MN180249.1__QHJ75400.1__X__00002__D85-208

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00023.37 best	Ank	19.3	1.60e-03	25.7%	97.0%

D3 medium residues 303-363

PDB

Domain cluster: representative

CATH (18)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4hwdD00	1.20.58.120	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain	0.71	60.0	5.26e-01	93.4%	85.6%
3pe0A02	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.70	58.0	4.88e-01	93.4%	84.0%
7odyC01	1.10.287.1080	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like	0.69	53.0	4.58e-01	82.0%	64.1%
4hwhE00	1.20.58.120	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain	0.68	58.0	5.14e-01	95.1%	84.1%
1yo7A00	1.20.120.230	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like	0.67	54.0	4.37e-01	90.2%	71.7%
1zeeA01	1.20.58.600	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.65	56.0	4.60e-01	100.0%	94.1%
1jnrA03	1.20.58.100	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain	0.65	54.0	4.42e-01	96.7%	65.3%
1f5oA00	1.10.490.10	Mainly Alpha › Orthogonal Bundle › Globin-like › Globins	0.64	46.0	3.49e-01	77.0%	60.4%
1oxjA02	1.25.40.170	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Smaug, PHAT domain	0.62	50.0	4.32e-01	96.7%	75.2%
2z16B01	1.20.91.10	Mainly Alpha › Up-down Bundle › Influenza Virus Matrix Protein; Chain A, domain 1 › Influenza matrix M1, N-terminal subdomain 1	0.62	49.0	4.60e-01	96.7%	70.5%
1v07A00	1.10.490.10	Mainly Alpha › Orthogonal Bundle › Globin-like › Globins	0.59	50.0	4.21e-01	96.7%	95.5%
7ocsB01	1.10.1040.10	Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2	0.59	47.0	3.58e-01	95.1%	41.6%
1kpsB00	1.25.40.200	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ran-GTPase activating protein 1, C-terminal domain	0.58	47.0	3.72e-01	100.0%	70.5%
1ashA00	1.10.490.10	Mainly Alpha › Orthogonal Bundle › Globin-like › Globins	0.54	42.0	3.35e-01	91.8%	92.5%
3q9dB01	1.20.58.1050	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.54	43.0	3.96e-01	95.1%	87.6%
4iluA02	1.20.58.1290	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain	0.54	44.0	3.80e-01	100.0%	64.9%
2nrlA00	1.10.490.10	Mainly Alpha › Orthogonal Bundle › Globin-like › Globins	0.53	43.0	3.41e-01	95.1%	69.0%
1w63Q00	3.30.450.60	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase ›	0.52	36.0	2.77e-01	72.1%	69.6%

ECOD (7)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3580914	604.12.1.2 ↗	alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1	0.68	54.0	4.87e-01	86.9%	76.5%
3807085	604.3.1.1 ↗	alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG	0.65	51.0	4.73e-01	93.4%	85.9%
4027698	2008.1.1.0 ↗	a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like	0.64	56.0	3.65e-01	100.0%	27.5%
4954682	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.64	56.0	4.86e-01	100.0%	85.3%
3461370	604.3.1.0 ↗	alpha bundles › Spectrin repeat-like › BAG domain › BAG domain	0.63	50.0	4.61e-01	93.4%	85.9%
3449672	138.1.1.2 ↗	alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › Rep_fac_C	0.57	50.0	4.32e-01	96.7%	63.2%
3263033	601.1.2.0 ↗	alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608)	0.55	43.0	3.73e-01	95.1%	67.3%

D4 medium residues 364-436

PDB

Domain cluster: rep: Ankyrin_repeat_protein_-25-__YP_010377004__Monkeypox_virus__10244__D312-400

D5 medium residues 514-615

PDB

Domain cluster: rep: ankyrin-repeat_protein__YP_009408397__NY_014_poxvirus__2025360__D494-567

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF09372.16 best	PRANC	69.9	2.60e-19	93.1%	97.9%