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Cy218

Euk-Vir

Cynomolgus_cytomegalovirus

Cy218__YP_009337610__Cynomolgus_cytomegalovirus__1919083

Identity

Accession:
YP_009337610 ↗
Protein ID:
Cy218
Kingdom:
euk

Quality

79.6 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 15-153_270-294
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF00001.27 best 7tm_1 57.7 1.80e-15 76.2% 48.1%
PF10320.16 7TM_GPCR_Srsx 32.4 9.30e-08 71.3% 33.9%
D2 medium residues 154-269
PDB
Domain cluster: representative
CATH (50)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4xt1A00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.80 73.0 5.31e-01 100.0% 38.5%
1s35A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 46.0 4.95e-01 71.6% 68.3%
1cunA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 48.0 5.11e-01 70.7% 71.6%
4cgkA01 6.10.250.3150 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.76 62.0 5.02e-01 87.1% 87.9%
5unhA02 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.75 69.0 5.18e-01 100.0% 44.4%
7xk2R01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.74 68.0 5.18e-01 100.0% 44.5%
5lweA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.74 67.0 5.01e-01 97.4% 62.5%
6h9xA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.74 48.0 5.13e-01 70.7% 75.5%
3okqA00 1.20.58.1540 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain 0.73 52.0 5.11e-01 73.3% 76.8%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.72 47.0 5.59e-01 80.2% 100.0%
2b5uA02 1.10.287.620 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins 0.72 50.0 4.44e-01 70.7% 50.9%
2fb5A01 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.71 44.0 5.37e-01 79.3% 100.0%
3i9wA00 1.20.58.920 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 59.0 4.49e-01 89.7% 41.1%
8a1gC01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.71 58.0 5.02e-01 88.8% 82.9%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.71 39.0 4.47e-01 75.9% 72.9%
1t98A02 1.20.58.590 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain 0.70 51.0 4.60e-01 76.7% 67.5%
1uurA01 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.70 48.0 4.94e-01 70.7% 74.5%
7xv3R01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.69 64.0 4.80e-01 100.0% 46.1%
1vcsA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.68 45.0 4.73e-01 83.6% 75.5%
2i7uA00 6.10.250.1010 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.68 37.0 4.79e-01 75.9% 100.0%
2fcwA00 1.20.81.10 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain 0.68 47.0 4.91e-01 72.4% 78.3%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.67 46.0 4.97e-01 79.3% 82.8%
3hr0B01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.67 43.0 5.02e-01 73.3% 94.9%
4cqiA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 45.0 4.72e-01 70.7% 79.4%
2ch7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.65 45.0 3.36e-01 72.4% 94.5%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.65 47.0 4.82e-01 79.3% 79.1%
2x0cA01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.63 54.0 4.73e-01 94.8% 63.5%
2b3tB01 6.10.140.1980 Special › Helix non-globular › Helix Hairpins › 0.62 33.0 4.14e-01 79.3% 89.2%
5k3hB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.62 45.0 4.35e-01 81.9% 66.2%
4ijjB00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.61 52.0 5.08e-01 99.1% 83.1%
4wjg400 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.60 52.0 4.06e-01 96.6% 73.6%
3nftA00 1.20.1710.10 Mainly Alpha › Up-down Bundle › IpaD-like › IpaD-like 0.60 51.0 3.96e-01 94.0% 82.8%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.60 41.0 4.65e-01 75.0% 100.0%
3r6nA02 1.20.58.1060 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 50.0 4.60e-01 93.1% 82.6%
2c0uA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.59 47.0 4.17e-01 99.1% 58.6%
1gqeA01 1.20.58.410 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor 0.59 50.0 5.10e-01 98.3% 95.6%
1egdA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.58 43.0 4.01e-01 87.9% 62.4%
2v5cA03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.58 48.0 4.70e-01 94.0% 80.8%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.58 41.0 4.06e-01 88.8% 69.7%
2l10A00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.56 46.0 4.16e-01 87.9% 91.1%
1avoB00 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.56 47.0 4.46e-01 92.2% 79.3%
3tufA00 1.10.287.4300 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Stage III sporulation protein AH-like 0.56 45.0 4.52e-01 83.6% 93.9%
3nyjA00 1.20.120.770 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Amyloid precursor protein, E2 domain 0.56 45.0 3.92e-01 87.9% 77.9%
1c17M00 1.20.120.220 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ATP synthase, F0 complex, subunit A 0.56 42.0 3.99e-01 81.0% 99.3%
3u9jA00 1.20.120.520 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like 0.56 44.0 4.00e-01 84.5% 100.0%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.54 38.0 3.98e-01 75.0% 80.7%
2wb7A03 1.20.120.870 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain 0.53 46.0 4.37e-01 95.7% 91.9%
2ihr101 1.20.58.410 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor 0.53 41.0 4.28e-01 90.5% 93.4%
2lquA01 1.20.1420.40 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Decorin-binding protein 0.53 42.0 3.88e-01 87.1% 90.9%
4ysxC00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.52 42.0 3.91e-01 94.8% 68.0%
ECOD (48)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3240501 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.81 51.0 4.80e-01 70.7% 52.9%
3867833 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.80 74.0 5.39e-01 100.0% 40.7%
3883423 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.79 73.0 5.22e-01 100.0% 37.4%
3902178 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.79 73.0 5.20e-01 100.0% 37.2%
3770671 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.77 72.0 5.02e-01 100.0% 35.9%
3519344 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.77 72.0 5.06e-01 100.0% 62.1%
4855949 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.76 70.0 6.10e-01 100.0% 68.4%
3872789 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.75 69.0 5.01e-01 100.0% 39.3%
4165790 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.75 68.0 5.32e-01 100.0% 93.1%
4413541 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.74 68.0 4.94e-01 100.0% 89.2%
3848908 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.73 67.0 4.78e-01 100.0% 38.2%
3217273 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.73 66.0 4.71e-01 100.0% 64.7%
5012794 4333.1.1.0 a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain 0.72 54.0 3.73e-01 78.4% 25.1%
4879104 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.72 66.0 5.75e-01 100.0% 67.1%
3655688 3755.3.1.303 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A_4th 0.71 50.0 4.37e-01 72.4% 94.3%
3224284 603.3.1.0 alpha bundles › STAT-like › CAPPD, an extracellular domain of amyloid beta A4 protein › CAPPD, an extracellular domain of amyloid beta A4 protein 0.71 60.0 5.24e-01 91.4% 69.1%
3845925 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.71 47.0 4.66e-01 73.3% 63.2%
3941435 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.70 57.0 5.30e-01 89.7% 72.0%
3350514 3922.1.1.145 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › KIF21A_4th 0.69 51.0 4.56e-01 75.9% 58.7%
3616967 603.1.1.97 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE 0.69 54.0 4.19e-01 82.8% 75.3%
3962893 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.69 48.0 5.22e-01 71.6% 97.9%
4608200 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.69 49.0 4.78e-01 75.0% 67.2%
4975039 1174.1.1.1 alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 › TMEM175 0.69 57.0 4.69e-01 88.8% 80.5%
3638080 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.68 50.0 4.60e-01 85.3% 58.7%
3958913 150.8.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE 0.68 57.0 4.90e-01 90.5% 80.6%
3899412 5069.1.3.67 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › 7tm_1 0.68 61.0 5.97e-01 98.3% 92.0%
4038268 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.68 58.0 5.86e-01 94.0% 91.3%
3318812 192.8.1.248 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › KIF21A_4th 0.68 50.0 4.56e-01 76.7% 66.0%
4957605 5076.2.1.13 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › DUF7847 0.68 48.0 3.83e-01 84.5% 38.2%
3994884 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.66 59.0 4.34e-01 99.1% 58.7%
3449357 150.1.1.110 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › DUF7358 0.65 50.0 4.43e-01 81.9% 60.6%
3485540 603.1.1.1 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin 0.65 49.0 4.29e-01 79.3% 56.0%
3337008 192.2.1.60 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › KIF21A_4th 0.64 50.0 4.71e-01 81.9% 77.9%
3237264 3755.4.1.82 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Snf7 0.64 49.0 4.73e-01 81.0% 94.6%
3298709 605.1.1.141 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Rx_N 0.64 53.0 5.25e-01 97.4% 85.6%
3443866 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.64 55.0 5.22e-01 95.7% 80.0%
3394756 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.64 56.0 4.15e-01 97.4% 44.0%
3819233 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.63 51.0 5.17e-01 94.8% 87.0%
3306743 192.29.1.101 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Rx_N 0.63 52.0 4.99e-01 97.4% 78.5%
4200274 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.62 51.0 5.34e-01 94.0% 98.1%
3479160 192.10.1.0 alpha bundles › Long alpha-hairpin › DnaK suppressor protein DksA, alpha-hairpin domain › DnaK suppressor protein DksA, alpha-hairpin domain 0.61 54.0 5.21e-01 100.0% 84.4%
3511712 5069.1.3.66 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › 7TM_GPCR_Srw 0.61 50.0 4.80e-01 89.7% 80.0%
4095116 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.60 51.0 5.21e-01 98.3% 93.9%
3598146 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.60 44.0 4.66e-01 89.7% 90.0%
3514684 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.56 40.0 4.10e-01 76.7% 76.5%
3608199 1189.1.1.0 alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor 0.55 47.0 4.16e-01 99.1% 83.2%
3594129 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.55 48.0 4.01e-01 100.0% 87.4%
4126623 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.52 46.0 2.96e-01 100.0% 56.6%