Back to structures

Cy46

Euk-Vir

Cynomolgus_cytomegalovirus

Cy46__YP_009337478__Cynomolgus_cytomegalovirus__1919083

Identity

Accession:
YP_009337478 ↗
Protein ID:
Cy46
Kingdom:
euk

Quality

79.5 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D2 medium residues 92-188_381-392_488-530
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05999.17 best Herpes_U5 45.8 6.00e-12 36.2% 9.0%
D3 medium residues 189-270_352-380
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05999.17 best Herpes_U5 76.2 3.40e-21 75.7% 17.0%
CATH (47)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2d2sA01 1.20.58.1210 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain 0.69 45.0 4.46e-01 84.7% 62.1%
3kp9A01 1.20.1440.130 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › VKOR domain 0.69 64.0 5.54e-01 100.0% 80.2%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.68 63.0 6.16e-01 100.0% 92.5%
6wv5A01 1.20.1440.130 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › VKOR domain 0.68 61.0 5.65e-01 96.4% 100.0%
4it4A02 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.67 47.0 5.11e-01 83.8% 87.9%
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.66 60.0 5.47e-01 100.0% 77.6%
1xg2B00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.65 59.0 5.35e-01 100.0% 75.5%
2e8gA01 1.20.1440.150 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.64 56.0 5.40e-01 95.5% 95.2%
1lqsL01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.63 50.0 5.28e-01 100.0% 94.0%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 50.0 4.66e-01 83.8% 75.0%
4a25B01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.62 53.0 4.70e-01 100.0% 64.6%
1mhyG01 1.20.1280.10 Mainly Alpha › Up-down Bundle › Monooxygenase › Methane monooxygenase, gamma chain, domain 1 0.62 36.0 4.43e-01 91.9% 94.1%
5ffdA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.62 53.0 4.94e-01 100.0% 75.9%
2lt3A01 1.20.58.1290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain 0.61 36.0 3.75e-01 81.1% 62.0%
2c2jA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.61 52.0 4.59e-01 100.0% 63.0%
2r8qA00 1.10.1300.10 Mainly Alpha › Orthogonal Bundle › Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b › 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain 0.61 53.0 3.74e-01 93.7% 92.2%
1bf5A01 1.20.1050.20 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain 0.60 47.0 4.10e-01 82.9% 78.6%
2qywA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.60 47.0 5.07e-01 83.8% 97.9%
3hiuD00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.60 53.0 4.75e-01 100.0% 70.4%
3bt5A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.60 54.0 4.87e-01 99.1% 76.8%
2pfdA03 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.59 53.0 4.38e-01 100.0% 68.5%
4hd1A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.59 52.0 3.90e-01 94.6% 88.2%
1i1rB00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.59 53.0 4.66e-01 100.0% 68.9%
1fntc01 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.59 46.0 3.86e-01 82.9% 59.0%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.59 47.0 4.81e-01 84.7% 90.6%
2g2dA00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.58 52.0 4.64e-01 100.0% 72.5%
3pwxA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.58 44.0 3.73e-01 83.8% 48.9%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.58 45.0 4.78e-01 82.9% 94.9%
5nl6A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 46.0 4.70e-01 84.7% 91.7%
3ez0C00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.57 49.0 3.99e-01 100.0% 50.0%
3k3oA02 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 41.0 4.65e-01 81.1% 98.8%
1f45B00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.56 48.0 4.51e-01 91.9% 76.7%
3ck6C02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.56 44.0 4.35e-01 84.7% 85.7%
1fioA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 44.0 3.71e-01 84.7% 54.2%
5c4yA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 41.0 3.85e-01 85.6% 64.7%
4l8iB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.53 42.0 4.24e-01 84.7% 94.6%
5lweA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.53 47.0 3.58e-01 99.1% 68.0%
3m9vA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.53 46.0 4.20e-01 100.0% 80.9%
3wmeA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.53 45.0 3.29e-01 93.7% 83.4%
2wdqD00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.53 39.0 4.01e-01 76.6% 92.4%
2hqcA01 1.20.1640.10 Mainly Alpha › Up-down Bundle › Multidrug efflux transporter AcrB transmembrane fold › Multidrug efflux transporter AcrB transmembrane domain 0.53 42.0 3.56e-01 89.2% 94.1%
3ctwB00 1.10.8.930 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Protein of unknown function DUF1465 0.52 46.0 4.55e-01 100.0% 91.7%
5gj7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.51 45.0 4.12e-01 100.0% 90.7%
5zbqA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.51 44.0 3.36e-01 99.1% 82.3%
3no6A00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.51 45.0 3.59e-01 100.0% 49.8%
2nrlA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.51 43.0 3.96e-01 91.9% 97.9%
3zdqA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.51 44.0 3.13e-01 94.6% 80.5%
ECOD (54)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4928363 150.1.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Ferritin 0.73 48.0 4.65e-01 100.0% 59.1%
5029785 633.22.1.1 alpha bundles › Bromodomain-like › Vitamin K epoxide reductase (VKOR) › Vitamin K epoxide reductase (VKOR) › VKOR 0.72 66.0 6.10e-01 99.1% 96.4%
3207001 633.23.1.22 alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.70 65.0 5.99e-01 100.0% 85.7%
3194196 633.23.1.22 alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.70 65.0 5.96e-01 100.0% 82.9%
4652595 633.23.1.22 alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.69 65.0 5.72e-01 100.0% 90.3%
3744370 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.69 64.0 5.88e-01 100.0% 88.6%
3417891 633.21.1.18 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CASP_dom 0.68 63.0 5.61e-01 100.0% 96.1%
4025329 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.68 63.0 5.86e-01 100.0% 88.1%
3994022 633.21.1.23 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 0.68 63.0 5.78e-01 100.0% 85.0%
3348350 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.68 62.0 5.33e-01 100.0% 75.9%
3232632 633.10.1.15 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › Transmemb_17 0.67 63.0 5.94e-01 100.0% 98.5%
3383516 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.67 61.0 5.81e-01 100.0% 86.2%
3835373 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.66 61.0 5.46e-01 100.0% 76.0%
3830809 633.4.1.0 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor 0.66 60.0 5.91e-01 100.0% 95.0%
3918623 174.1.1.43 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 0.66 61.0 5.53e-01 100.0% 77.9%
3212117 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.66 61.0 5.33e-01 100.0% 89.4%
3803172 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.66 61.0 5.34e-01 100.0% 75.6%
3795935 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.66 60.0 5.19e-01 100.0% 92.4%
3802170 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.66 59.0 5.37e-01 99.1% 76.0%
3617743 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.66 60.0 5.51e-01 100.0% 92.4%
3408573 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.66 60.0 5.59e-01 100.0% 84.8%
3721623 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.66 59.0 5.38e-01 100.0% 83.3%
3836689 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.65 59.0 5.37e-01 100.0% 74.0%
3941250 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.64 51.0 5.12e-01 82.9% 91.8%
1434745 192.4.1.1 alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Ribosomal_L29 0.64 40.0 4.79e-01 96.4% 97.2%
4972007 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.63 55.0 5.14e-01 100.0% 75.7%
3931312 601.1.2.6 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_IBS2B 0.62 46.0 4.56e-01 83.8% 73.3%
3761396 109.4.1.1893 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ICE1_C 0.62 43.0 3.02e-01 82.0% 22.5%
3223368 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.61 55.0 4.95e-01 100.0% 77.4%
3919843 604.1.1.124 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_6 0.61 48.0 4.60e-01 83.8% 88.5%
3228159 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.61 48.0 4.33e-01 83.8% 67.3%
3176244 633.15.1.3 alpha bundles › Bromodomain-like › alpha-ketoacid dehydrogenase kinase-N › alpha-ketoacid dehydrogenase kinase-N › SOG2 0.61 54.0 4.88e-01 100.0% 75.5%
3936737 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.60 54.0 4.35e-01 100.0% 95.0%
3486748 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.60 47.0 4.88e-01 83.8% 95.2%
3764093 6171.1.1.1 alpha bundles › C-terminal helical domain in Jumonji domain-containing histone demethylases › C-terminal helical domain in Jumonji domain-containing histone demethylases › C-terminal helical domain in Jumonji domain-containing histone demethylases › JHD 0.60 43.0 4.62e-01 78.4% 86.3%
3569625 604.12.1.4 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › ATG1-like_MIT1 0.60 47.0 4.34e-01 84.7% 81.4%
3519581 604.12.1.4 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › ATG1-like_MIT1 0.60 47.0 4.43e-01 83.8% 83.7%
3498827 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.59 46.0 4.66e-01 82.0% 96.4%
3615244 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.59 47.0 4.13e-01 82.9% 64.4%
4021392 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.59 51.0 3.63e-01 92.8% 52.8%
3956517 5069.1.3.3 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › Fumarate_red_D 0.59 40.0 3.97e-01 70.3% 95.0%
4100527 604.8.1.2 alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo › Mitofilin 0.58 46.0 4.48e-01 84.7% 84.0%
2396196 601.1.2.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin 0.58 44.0 4.20e-01 84.7% 67.4%
3185802 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.58 51.0 4.86e-01 100.0% 91.9%
3218642 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.57 45.0 4.50e-01 84.7% 89.6%
3250233 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.57 51.0 4.28e-01 98.2% 65.4%
3313293 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.56 51.0 4.25e-01 100.0% 62.6%
4261753 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 51.0 4.32e-01 100.0% 96.8%
3831677 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.55 49.0 3.82e-01 95.5% 70.4%
3264889 1128.1.1.1 alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR 0.55 36.0 3.97e-01 78.4% 84.7%
5026085 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.53 42.0 4.30e-01 85.6% 100.0%
3240880 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.52 43.0 3.11e-01 91.9% 83.1%
3440913 4006.1.1.0 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain 0.52 39.0 3.70e-01 80.2% 83.0%
4989575 2004.1.1.29 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.51 39.0 2.42e-01 100.0% 13.9%
D4 medium residues 289-351
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05999.17 best Herpes_U5 76.7 2.60e-21 100.0% 13.3%