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D5_family_helicase-primase

Euk-Vir

Acanthamoeba_polyphaga_moumouvirus

D5_family_helicase-primase__YP_007354213__Acanthamoeba_polyphaga_moumouvirus__1269028

Identity

Accession:
YP_007354213 ↗
Protein ID:
D5_family_helicase-primase
Kingdom:
euk

Quality

54.9 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 24-80
PDB
Domain cluster: representative
CATH (28)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1vw4L02 1.10.246.170 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.69 58.0 5.17e-01 100.0% 88.2%
1dk5A04 1.10.220.10 Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Annexin 0.64 56.0 5.24e-01 100.0% 98.6%
5m9dA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.63 56.0 4.23e-01 100.0% 85.5%
3ebbA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.58 48.0 3.20e-01 98.2% 29.2%
3e3vA03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.58 41.0 4.16e-01 77.2% 94.6%
4dloB02 1.25.40.610 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.57 48.0 3.91e-01 98.2% 70.9%
1x4pA00 1.10.10.790 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Surp module 0.57 40.0 3.85e-01 75.4% 84.8%
3tl4X02 1.10.10.2420 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.56 39.0 3.73e-01 75.4% 83.3%
2ptfB02 1.20.58.290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121. 0.56 47.0 4.70e-01 93.0% 100.0%
1ym3A00 3.40.1050.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-carbonic Anhydrase; Chain A › Carbonic anhydrase 0.56 48.0 3.36e-01 98.2% 60.1%
3k3oA02 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 48.0 4.28e-01 98.2% 88.1%
1hu3A00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.55 47.0 3.30e-01 100.0% 56.4%
2guzA00 1.10.287.110 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain 0.55 40.0 3.80e-01 80.7% 88.7%
1x4oA00 1.10.10.790 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Surp module 0.54 38.0 3.58e-01 78.9% 76.9%
8e9gE01 1.10.10.1590 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › NADH-quinone oxidoreductase subunit E 0.54 39.0 3.81e-01 78.9% 84.1%
3w0lD02 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.54 46.0 2.90e-01 100.0% 26.6%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.53 46.0 4.02e-01 96.5% 82.4%
2p6nA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 45.0 3.34e-01 100.0% 64.4%
4hwhE00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.52 44.0 3.88e-01 98.2% 84.1%
1fc6A01 3.30.750.44 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › 0.52 45.0 3.82e-01 100.0% 72.4%
2rcnA03 1.10.40.50 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Probable gtpase engc; domain 3 0.52 42.0 4.13e-01 91.2% 91.9%
6xm1A02 3.90.830.10 Alpha Beta › Alpha-Beta Complex › Syntaxin Binding Protein 1; Chain A, domain 2 › Sec1/Munc18 (SM) protein, domain 3a 0.52 38.0 3.16e-01 82.5% 61.1%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.51 44.0 4.07e-01 98.2% 93.2%
3mzkB03 1.20.58.940 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 40.0 3.85e-01 100.0% 75.7%
1vbgA04 1.10.189.10 Mainly Alpha › Orthogonal Bundle › Pyruvate Phosphate di-kinase; domain 2 › Pyruvate Phosphate Dikinase, domain 2 0.51 42.0 4.10e-01 94.7% 100.0%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.50 43.0 3.86e-01 100.0% 84.7%
1xdxA01 3.30.1140.40 Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › Tctex-1 0.50 40.0 3.46e-01 93.0% 96.0%
4yj6A00 3.90.1300.10 Alpha Beta › Alpha-Beta Complex › Amidase signature (AS) enzymes › Amidase signature (AS) domain 0.50 36.0 2.20e-01 82.5% 48.4%
ECOD (17)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3816589 109.4.1.1280 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_long 0.73 63.0 3.79e-01 100.0% 17.2%
3670388 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.63 44.0 3.37e-01 73.7% 47.4%
3761824 101.1.1.21 alpha arrays › HTH › HTH › Three-helical HTH › HTH_Tnp_Tc5 0.60 48.0 4.49e-01 87.7% 82.9%
5002559 2.21.1.0 beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) 0.60 45.0 3.25e-01 80.7% 37.0%
4508795 7000.1.1.0 alpha arrays › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS 0.60 42.0 3.74e-01 73.7% 96.2%
3933315 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.58 48.0 4.13e-01 100.0% 74.0%
3764093 6171.1.1.1 alpha bundles › C-terminal helical domain in Jumonji domain-containing histone demethylases › C-terminal helical domain in Jumonji domain-containing histone demethylases › C-terminal helical domain in Jumonji domain-containing histone demethylases › JHD 0.56 49.0 4.15e-01 98.2% 78.9%
4358621 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.55 42.0 3.86e-01 86.0% 69.6%
4289855 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.55 45.0 4.39e-01 93.0% 92.3%
2124338 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.55 43.0 3.91e-01 89.5% 65.4%
4009660 604.1.1.21 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › DUF2645 0.54 41.0 3.37e-01 82.5% 87.5%
4992790 601.2.1.0 alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes 0.54 48.0 4.06e-01 100.0% 66.3%
3719058 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.54 44.0 3.93e-01 93.0% 76.5%
3341807 604.3.1.1 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG 0.53 45.0 3.71e-01 98.2% 70.0%
1145756 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.52 45.0 3.61e-01 100.0% 59.0%
3199446 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.52 42.0 3.62e-01 96.5% 59.0%
3364093 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.51 39.0 3.80e-01 89.5% 80.0%
D2 medium residues 115-193
PDB